CN110506879A - A kind of solid beverage and its preparation method for alleviating visual fatigue - Google Patents
A kind of solid beverage and its preparation method for alleviating visual fatigue Download PDFInfo
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- CN110506879A CN110506879A CN201910727572.2A CN201910727572A CN110506879A CN 110506879 A CN110506879 A CN 110506879A CN 201910727572 A CN201910727572 A CN 201910727572A CN 110506879 A CN110506879 A CN 110506879A
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- CN
- China
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- powder
- solid beverage
- lutein
- visual fatigue
- zeaxanthin
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- 239000003814 drug Substances 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000013505 freshwater Substances 0.000 description 1
- 235000012055 fruits and vegetables Nutrition 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000002189 macula lutea Anatomy 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000000845 maltitol Substances 0.000 description 1
- 235000010449 maltitol Nutrition 0.000 description 1
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 1
- 229940035436 maltitol Drugs 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 235000019533 nutritive sweetener Nutrition 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- 229920002414 procyanidin Polymers 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000002207 retinal effect Effects 0.000 description 1
- 108010021975 retinal isomerase Proteins 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000004855 vascular circulation Effects 0.000 description 1
- 230000004382 visual function Effects 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000008210 xanthophylls Nutrition 0.000 description 1
- 208000005494 xerophthalmia Diseases 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 239000001052 yellow pigment Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Botany (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a kind of solid beverages and preparation method thereof for alleviating visual fatigue, wherein alleviates the solid beverage of visual fatigue, it includes, 0.01~0.2 part of lutein, 1~2 part of blueberry powder, 3~5 parts of D-sorbite, 1~3 part of inulin, 0.5~2 part of vegetables and fruits ferment powder, 0.5~2 part of grape juice powder, 0.01~0.05 part of zeaxanthin, 0~0.1 part of haematococcus pluvialis, 0~0.3 part of beta carotene.Product of the present invention has natural fruit flavor as a kind of solid beverage for alleviating asthenopia, ingredient cleaning, and each mutual compatibility of functional component reaches efficient eyeshield, alleviates the purpose of eye strain.Product of the present invention is safe and effective, and having no toxic side effect directly to eat, and can also reconstitute into flavour beverage full of nutrition.
Description
Technical field
The invention belongs to technical field of beverage, and in particular to a kind of solid beverage for alleviating visual fatigue and its preparation side
Method.
Background technique
With the extensive use of the electronic products such as mobile phone, computer, people are increasingly longer in face of the time of electronic curtain.It grinds
Study carefully show nearly 70% adult feel in routine use electronic product eyes discomfort, occur eye strain, hypopsia,
The visual fatigues symptom such as dry eyes, eye-blurred, retinal damage.The main reason for causing visual fatigue is excess eye-using and electrical screen
Damage of the high energy blue light that curtain issues to macula retinae area.Contain a large amount of high energy blue light in the light such as mobile phone, computer, LED
(440 nanometers of wavelength), go directly retina, is gathered in macular area, therefore photochemical damage also occurs mainly in macular area.Macular area view
Nethike embrane is the most sensitive position of visual function, and the polyunsaturated fatty acid with high concentration, the oxidative damage caused by blue light is especially
It is sensitive.
For these problems, the existing eyeshield therapeutic equipments for alleviating symptom, also there is the eyeshield of traditional Chinese medicine ingredients currently on the market
The health food of nourishing the liver, but it is all extremely limited to the reparation of the damage of eye and improvement result for blue light, and there are human body suctions
Receive the problems such as utilization rate is low, label is unclean.Chinese patent 201711422498.0 discloses a kind of blueberry lutein ester piece,
Distinguishing feature is that blueberry and lutein ester compatibility are complementary to one another nutrition, alleviates visual fatigue, but studies have reported that, with serum
Lutein monomer value is reference, and the relative bioavailability of measurement lutein ester in vivo is 18.55%, is added in such invention
The lutein ester added can not effectively be absorbed by human body, and utilization rate is too low.Chinese patent 201310058405.6 discloses one kind
Xanthophyll chewable tablet Lutein powder, by xylitol, vitamin C, maltitol, maltodextrin, soluble dietary fiber, orange
Chewable tablets is made in the ingredients such as essence, Aspartame, magnesium stearate, but the auxiliary materials such as filler are more in product, and effect is poor, product
Formula not enough cleaning.
Summary of the invention
The purpose of this section is to summarize some aspects of the embodiment of the present invention and briefly introduce some preferable implementations
Example.It may do a little simplified or be omitted to avoid our department is made in this section and the description of the application and the title of the invention
Point, the purpose of abstract of description and denomination of invention it is fuzzy, and this simplification or omit and cannot be used for limiting the scope of the invention.
In view of it is above-mentioned/or a kind of existing solid beverage and preparation method thereof for alleviating visual fatigue there are the problem of, propose
The present invention.
Therefore, the one of purpose of the present invention is to overcome the deficiencies of the prior art and provide a kind of solid for alleviating visual fatigue
Beverage and preparation method thereof.
In order to solve the above technical problems, according to an aspect of the present invention, the present invention provides the following technical scheme that a kind of
Alleviate the solid beverage of visual fatigue, including, lutein, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice powder, jade
Cream-coloured matter, haematococcus pluvialis and beta carotene；Wherein, in terms of mass fraction, the lutein is 0.01~0.2 part, described
Blueberry powder is 1~2 part, and the D-sorbite is 3~5 parts, and the inulin is 1~3 part, and the vegetables and fruits ferment powder is 0.5~2
Part, the grape juice powder is 0.5~2 part, and the zeaxanthin is 0.01~0.05 part, and the haematococcus pluvialis is 0~0.1
Part, the beta carotene is 0~0.3 part.
As the solid beverage a kind of preferred embodiment of the present invention for alleviating visual fatigue, in which: the lutein is 0.2
Part, the blueberry powder is 2 parts, and the D-sorbite is 5 parts, and the inulin is 3 parts, and the vegetables and fruits ferment powder is 2 parts, the Portugal
Grape juice powder is 2 parts, and the zeaxanthin is 0.05 part, and the haematococcus pluvialis is 0.1 part, and the beta carotene is 0.3 part.
As the solid beverage a kind of preferred embodiment of the present invention for alleviating visual fatigue, in which: in the haematococcus pluvialis
Content astaxanthin is 6%~9%.
As the solid beverage a kind of preferred embodiment of the present invention for alleviating visual fatigue, in which: the lutein, maize
Matter is both from marigold flower.
As the solid beverage a kind of preferred embodiment of the present invention for alleviating visual fatigue, in which: the vegetables and fruits ferment powder is
Fresh water fruits and vegetables are made after everfermentation, pretreatment, freeze-drying, ultraviolet-sterilization.
As the solid beverage a kind of preferred embodiment of the present invention for alleviating visual fatigue, in which: the Fruit powder, being will be new
After freeze-drying, preprocessed, quick-frozen, vacuum drying, ultraviolet sterilization process are process fresh fruit.
Another object of the present invention is to provide a kind of preparation method of solid beverage for alleviating visual fatigue.
In order to solve the above technical problems, according to an aspect of the present invention, the present invention provides the following technical scheme that a kind of
Alleviate the production method of the solid beverage of visual fatigue, including, pretreatment: by lutein, blueberry powder, D-sorbite, inulin, vegetables and fruits
Ferment powder, grape juice powder, zeaxanthin, haematococcus pluvialis, beta carotene sieve with 100 mesh sieve respectively, spare；Solid beverage is matched
System: by the lutein of pretreatment sieving, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice powder, zeaxanthin, rain
Raw haematococcus, beta carotene are uniformly mixed according to a certain percentage to get the solid beverage；Product packing: by above-mentioned mixing
Uniform solid beverage is packaged processing.
A kind of preferred embodiment of production method as the solid beverage of the present invention for alleviating visual fatigue, in which: described
Solid beverage is prepared, and in terms of mass fraction, the lutein is 0.01~0.2 part, and the blueberry powder is 1~2 part, the sorb
Sugar alcohol is 3~5 parts, and the inulin is 1~3 part, and the vegetables and fruits ferment powder is 0.5~2 part, and the grape juice powder is 0.5~2
Part, the zeaxanthin is 0.01~0.05 part, and the haematococcus pluvialis is 0~0.1 part, and the beta carotene is 0~0.3
Part.
A kind of preferred embodiment of production method as the solid beverage of the present invention for alleviating visual fatigue, in which: described
Product packing refers to and solid beverage is encapsulated into resistance oxygen, in the inner bag that blocks water point, be protected from light.
Beneficial effects of the present invention:
(1) present invention is by lutein and zeaxanthin scientific matching, the two can common high concentration, selectivity be deposited on Huang
Macular area, common filtering high energy blue light, prevention retina are injured by blue light.Meanwhile it is green by anthocyanidin in ingredient and shrimp
Free radical is quenched as high-quality antioxidant in element, protects macular area photoreceptor cell Membrane fatty acid from oxidative damage.Naturally
Beta carotene maintains vision as natural vitamin A source abundant.Lutein, zeaxanthin, anthocyanidin, astaxanthin and β-
Eye strain is alleviated in five kinds of mutual compatibilities of functional component of carrotene, efficient eyeshield, improves eyesight.
(2) present invention by other antioxidants of compatibility and hinder oxygen be protected from light manner of packing improvement lutein stability it is poor,
Easy to oxidize, the chance labile defect of light, keeps it stable in formula, to improve its effective rate of utilization.Meanwhile passing through addition
Prebiotics and other natural fruit powders, the good fluidity of composition, preferably performance composition alleviate visual fatigue, pre- myopic-preventing function
Effect.
(3) product of the present invention has natural fruit flavor as a kind of solid beverage for alleviating asthenopia, ingredient cleaning,
It due to the good instant capacity of ingredient and flavor, can directly eat, flavour beverage full of nutrition can also be reconstituted into.
(4) compatibility of the present invention is reasonable, safely and effectively, has no toxic side effect.For the race of bowing commonly using mobile phone, long-time
All may be used in face of the busy student of the office clan of computer, the children for loving to play game machine, homework, long-time motorist and the middle-aged and the old
To alleviate eye strain problem by this patent product, eye health is protected, there is vast market prospect.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, below with reference to specification embodiment
Specific embodiments of the present invention will be described in detail.
In the following description, numerous specific details are set forth in order to facilitate a full understanding of the present invention, but the present invention can be with
Implemented using other than the one described here other way, those skilled in the art can be without prejudice to intension of the present invention
In the case of do similar popularization, therefore the present invention is not limited by the specific embodiments disclosed below.
Secondly, " one embodiment " or " embodiment " referred to herein, which refers to, may be included at least one realization side of the invention
A particular feature, structure, or characteristic in formula." in one embodiment " that different places occur in the present specification not refers both to
The same embodiment, nor the individual or selective embodiment mutually exclusive with other embodiments.
Raw material lutein, blueberry powder (anthocyanidin content 25%), D-sorbite, inulin, vegetables and fruits ferment powder, Portugal in the present invention
Grape juice powder, zeaxanthin, haematococcus pluvialis (content astaxanthin is 6%~9%), beta carotene are commercially available.
Embodiment 1
Pretreatment: by lutein, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice powder, zeaxanthin, rain
Raw haematococcus, beta carotene sieve with 100 mesh sieve respectively, spare；
Solid beverage is prepared: in terms of mass fraction, take 5 parts of pretreated D-sorbite, 3 parts of inulin, and vegetables and fruits powder ferment 2
Part, 2 parts of grape fruit powder, 2 parts of the blueberry powder of anthocyanidin content 25%, 0.2 part of lutein, 0.05 part of zeaxanthin, haematococcus pluvialis
It 0.1 part, 0.3 part of beta carotene, is uniformly mixed.
Product packing: solid beverage is encapsulated into resistance oxygen, in the inner bag that blocks water point, be protected from light.
Embodiment 2
Pretreatment: by lutein, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice powder, zeaxanthin, rain
Raw haematococcus, beta carotene sieve with 100 mesh sieve respectively, spare；
Solid beverage is prepared: in terms of mass fraction, take 0.2 part of pretreated lutein, 1.5 parts of blueberry powder, and sorbose
5 parts of alcohol, 3 parts of inulin, 1.5 parts of vegetables and fruits ferment powder, 1.5 parts of grape juice powder, 0.04 part of zeaxanthin, 0.04 part of haematococcus pluvialis,
It 0.1 part of beta carotene, is uniformly mixed；
Product packing: solid beverage is encapsulated into resistance oxygen, in the inner bag that blocks water point, be protected from light.
Embodiment 3
Pretreatment: by lutein, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice powder, zeaxanthin, rain
Raw haematococcus, beta carotene sieve with 100 mesh sieve respectively, spare；
Solid beverage is prepared: in terms of mass fraction, take 0.01 part of pretreated lutein, 1 part of blueberry powder, and D-sorbite
3 parts, 1 part of inulin, 0.5 part of vegetables and fruits ferment powder, 0.5 part of grape juice powder, 0.01 part of zeaxanthin, 0.1 part of haematococcus pluvialis, β-Hu
0.3 part of radish element, is uniformly mixed；
Product packing: solid beverage is encapsulated into resistance oxygen, in the inner bag that blocks water point, be protected from light.
Embodiment 4
Pretreatment: by lutein, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice powder, zeaxanthin, rain
Raw haematococcus, beta carotene sieve with 100 mesh sieve respectively, spare；
Solid beverage is prepared: in terms of mass fraction, take 0.3 part of pretreated lutein, 1.5 parts of blueberry powder, and sorbose
4 parts of alcohol, 2 parts of inulin, 1 part of vegetables and fruits ferment powder, 1 part of grape juice powder, 0.1 part of zeaxanthin, 0.06 part of haematococcus pluvialis, β-Hu Luo
It 0.2 part of Bu Su, is uniformly mixed；
Product packing: solid beverage is encapsulated into resistance oxygen, in the inner bag that blocks water point, be protected from light.
Efficacy experiments of the present invention: (1) it by embodiment and reference examples method prepares solid beverage 50 and wraps；
(2) alleviate visual fatigue functional check method:
Referring to alleviation visual fatigue functional check method in " health food is examined and assessment technique specification " (2003 editions) to this
Invention carries out power test.Eye, the fatigable volunteer of eyesight are used in selection for a long time, and the age between 10~50 years old, excludes
The subject for being included in age criterion is not met, to health food allergy sufferers, with eye disease etc., and is not taken in six months
Cross article related with tested function.
Every group of 50 subjects, with the presence of a variety of eye discomfort symptoms of several subjects, such as dry and astringent, photophobia, view in every group
A variety of symptoms such as power is fuzzy, eyes are dry and astringent, and number is uniformly distributed in the presence of I, II, III rank symptom as shown in table 1.Test
Using itself between group two kinds of control designs, be grouped according to random, double blind requirement, examined according to symptom and eyesight when grouping
Look into situation, make experimental group and the symptom of control group and food horizontal equalization, while considering the factors such as age, gender, make each group it
Between be all comparable.
(3) dosage and application method of tested material
Experimental group is taken by recommended method and recommended amounts, and control group takes placebo, and each group does not change eating habit, peace
The packaging, shape, dosage for consoling agent are consistent with experimental group, and 2 times a day, one bag each time.Respectively in 30 days testing indexs, each group is observed
Situation is evaluated in the improvement for the symptoms such as personnel's ophthalmodynia, eye are swollen, photophobia, eye-blurred, eye are dry and astringent.
(4) effect criterion
Symptom improves: ophthalmodynia, eye are swollen, photophobia, eye-blurred, the dry and astringent any symptom of eye improve 1 point and 1 point or more and as change
Kind, any improvement of 5 kinds of symptoms and other symptoms determine that symptom improves without deteriorating.Effectively, symptom improves and before duration of photopic vision
After differ by more than equal to 0.1, and have conspicuousness through statistical comparison difference.It is invalid: not up to effective standard.
Visual fatigue symptom determination method, is shown in Table 1.
Table 1
Remarks: random thoughts refer to 1~2 times/day；When have and refer to 1~3 times/day；Often refer to greater than 3 times/day, is more than or equal to 1
Divide and is then denoted as improvement.
The measurement of duration of photopic vision: according to alleviation visual fatigue in " health food is examined and assessment technique specification " (2003 editions)
" product " word figure measures duration of photopic vision in functional check method.
Visuognosis persistence test " product " word figure.
Duration of photopic vision=(the photopic vision time/watch total time attentively) * 100%, watching total time attentively is 180s.
The effective people's number/total number of improvement rate %=refers to symptom in vain to change or being aggravated, effectively refers to
Symptom disappears or improves.
Examples 1 to 4 symptom improves situation and duration of photopic vision, measurement result are shown in Table 2.
Table 2
Table 3
The each symptom of embodiment group has different degrees of improvement after testing it can be seen from the table 2, table 3, wherein eye
The dry and astringent improvement situation of swollen, photophobia, eye is preferable, and five indices are superior to control group.That placebo is taken in control group 1 also has one
Determine the improvement of degree, analysis reason may be due to caused by psychological application or diet.By compared with itself and and control group
It compares, difference has statistical significance (P < 0.01).Obviously eye is swollen, ophthalmodynia, photophobia, blurred vision, eye improving for embodiment group
Dry and astringent aspect has effect outstanding.
Simultaneously as can be seen that there was no significant difference for the duration of photopic vision of each group before testing.After experiment, subject's photopic vision is lasting
There were significant differences (P < 0.01) for degree, and control group of the embodiment group compared with before experiment and after experiment is compared, and duration of photopic vision is significant
It improves, it can thus be appreciated that embodiment tool is significantly improved and prevents the pre- myopic-preventing effect of persistence.
Lutein and zeaxanthin belong to carotenoid, the two isomer each other in structure.Lutein and
Zeaxanthin is natural, and free radical can effectively be quenched, so that macular area photoreceptor cell Membrane fatty acid be protected to exempt from
Oxidative damage.Macular area selective aggregation lutein and zeaxanthin can effectively filter the harmful blue light of high-energy in sunlight,
To the light injury for protecting macular area retina caused from sunlight irradiation.Lutein and zeaxanthin proportion of the present invention is closed
Reason is made on the basis of guaranteeing lutein and zeaxanthin effective additive amount by the scientific matching of lutein and zeaxanthin
The two plays preferable protecting effect to the macular area of retina.
Blueberry procyanidins can protect retina blood capillary, promote view regeneration of erythrocytes, improve eyesight, enhance eyes
To dark adaptability, alleviate asthenopia etc., mainly procyanidine acts on retinal isomerase, increases rhodopsin
Generating rate, while its synthesizing again in the dark can be promoted, improve retina to the sensitivity of light.Meanwhile as excellent
Natural, the anthocyanidin in blueberry can effectively reduce light injury degree, and repairing retina light injury promotes eye circumference micro-
Vascular circulation quickly eliminates visual fatigue, prevents, treats xerophthalmia.
Haematococcus pluvialis is the optimal natural astaxanthin source of nature, and astaxanthin be strongest natural it
One, it is 1000 times of vitamin E that the ability for removing free radical, which is ascorbic 6000 times,.Retina and macular area are rich in insatiable hunger
And fatty acid, therefore, the free radical for aoxidizing generation is easy to make cell that oxidative damage occur.Natural astaxanthin has superpower anti-oxidant
Ability, can efficiently anti-retina oxidation, repair oxidative damage, alleviating eye pressure prevents eyeground from turning yellow, anti-inflammatory.
Beta carotene can be changed into vitamin A after entering human body, and a molecule beta carotene is equivalent to 2 molecules
Vitamin A.Vitamin A is the ingredient for constituting photoactive substance in cellula visualis, and it is dry and astringent to improve eyes, prevents yctalopia.
Blueberry powder in solid beverage formula of the present invention contains abundant anthocyanidin, can effectively remove free radical, protection eye
Cell, meanwhile, haematococcus pluvialis and anthocyanidin, natural beta-carotin compatibility in lutein and blueberry are common to repair view
Nethike embrane oxidative damage, alleviating eye pressure prevents eyeground from turning yellow, and in conjunction with lutein and zeaxanthin rational proportion, makes it to view
The macular area of film plays optimal protecting effect.
Embodiment 5
On the basis of embodiment 1, influence of the different additives to properties of product is probed into, the results are shown in Table 4.
Table 4
Inulin has the characteristic for promoting probiotics to be significantly proliferated, and is directly entered large intestine, is preferentially utilized by probiotics, helps it big
Amount breeding is the proliferation factor of probiotics, inhibits the growth of harmful bacteria, the Tiny ecosystem in enteron aisle is promoted to adjust to benign cycle.
Pears sugar alcohol is not converted into glucose as nutritive sweeteners in human body, and not by the control of insulin, suitable diabetes patient makes
With.
It is currently, there are many nutriments, such as strawberry, pawpaw, corn, FRUCTUS TERMINALIAE IMMATURUS, effect and property difference, such as
The product that preferably alleviation visual fatigue effect is provided in what collocation is " difficult point " researched and developed at present.Lutein and zeaxanthin of the present invention
Proportion rationally, on the basis of guaranteeing lutein and zeaxanthin effective additive amount, passes through the science of lutein and zeaxanthin
Proportion, in conjunction with making blueberry powder, haematococcus pluvialis, inulin that there is synergistic effect, so that lutein and zeaxanthin are to retina
Macular area play optimal protecting effect.Raw material Lutein of the present invention, blueberry powder, inulin, zeaxanthin, haematococcus pluvialis
It mutually promotes between each component materials, has the effect of preferably alleviating visual fatigue, promotes eye health.
Functional component lutein, zeaxanthin, blueberry powder, beta carotene, haematococcus pluvialis are removed in inventive formulation
Except raw material, be added to prebiotics inulin, D-sorbite and vegetables and fruits ferment powder and grape juice powder, do not add other odium stearate,
Other auxiliary materials such as microcrystalline cellulose, ingredient cleaning.Meanwhile inner wrapping solid beverage can be made in the present invention, since ingredient is instant
Property, taste flavor are all preferable, direct-edible, can also reconstitute and take, more convenient.
Inventor has found the packet that blueberry powder, haematococcus pluvialis, inulin have collaboration antioxidation, are protected from light in conjunction with resistance oxygen
Dress mode, improve lutein stability it is poor, it is easy to oxidize, chance the labile defect of light, keep it stable in formula, to improve
Its effective rate of utilization.Be different from the prior art low bioavailability lutein ester or unsuitable process caused by leaf
Flavine decomposes loss.Meanwhile the present invention is by addition D-sorbite and other natural fruit powders, the good fluidity of composition, more preferably
Ground plays the effect of composition alleviates visual fatigue, pre- myopia prevention.
Lutein and zeaxanthin used in the present invention are both from marigold flower.In plant, lutein plays anti-
The effect of oxidant and the damage that photoinduction free radical is protected the plants from by filtering high-energy blue light.Human body cannot synthesize
Lutein, it is necessary to be obtained from food.In a variety of carotenoid that the mankind eat, only lutein and zeaxanthin goes out
In present retina and crystalline lens.In addition to this, there are no other any carotenoid to reach in some tissue
The deposition of high concentration, specificity, selectivity in this way.Eye macular area retina is rich in yellow pigment, mainly by lutein and jade
Cream-coloured texture is at being referred to as " macular pigment ".Studies have shown that intake can increase macula lutea rich in the food of lutein and zeaxanthin
Pigment density, and it is likely to decrease the onset risk of prevention senile macular degeneration disease (AMD).Macular area selective aggregation leaf is yellow
Element and zeaxanthin, can effectively filter the harmful blue light of high-energy in sunlight, so that macular area retina be protected to shine from sunlight
Penetrate caused light injury.In addition, macular area retinal metabolism is vigorous and possesses the polyunsaturated fatty acid of high concentration, therefore right
Oxidative damage is also very sensitive.Lutein and zeaxanthin are naturals, and free radical can effectively be quenched, to protect Huang
Macular area photoreceptor cell Membrane fatty acid is from oxidative damage.
To sum up, by compatibility other antioxidants, (blueberry powder, haematococcus pluvialis, inulin have collaboration antioxygen to the present invention
Change effect) and the manner of packing that is protected from light of resistance oxygen, improve that lutein stability is poor, easy to oxidize, the chance labile defect of light, makes it
It is stable in formula, to improve its effective rate of utilization.The lutein ester of low bioavailability or not in being different from the prior art
Lutein caused by process appropriate decomposes loss.Meanwhile the present invention passes through addition D-sorbite and other natural fruit powders,
The effect of good fluidity of composition, preferably performance composition alleviates visual fatigue, pre- myopia prevention.
It should be noted that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to preferable
Embodiment describes the invention in detail, those skilled in the art should understand that, it can be to technology of the invention
Scheme is modified or replaced equivalently, and without departing from the spirit and scope of the technical solution of the present invention, should all be covered in this hair
In bright scope of the claims.
Claims (9)
1. a kind of solid beverage for alleviating visual fatigue, it is characterised in that: including,
Lutein, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice powder, zeaxanthin, haematococcus pluvialis and β-Hu
Radish element；
Wherein, in terms of mass fraction, the lutein is 0.01~0.2 part, and the blueberry powder is 1~2 part, the D-sorbite
It is 3~5 parts, the inulin is 1~3 part, and the vegetables and fruits ferment powder is 0.5~2 part, and the grape juice powder is 0.5~2 part, institute
Stating zeaxanthin is 0.01~0.05 part, and the haematococcus pluvialis is 0~0.1 part, and the beta carotene is 0~0.3 part.
2. alleviating the solid beverage of visual fatigue according to claim 1, it is characterised in that: the lutein is 0.2 part, described
Blueberry powder is 2 parts, and the D-sorbite is 5 parts, and the inulin is 3 parts, and the vegetables and fruits ferment powder is 2 parts, the grape juice powder
It is 2 parts, the zeaxanthin is 0.05 part, and the haematococcus pluvialis is 0.1 part, and the beta carotene is 0.3 part.
3. the solid beverage according to claim 1 or claim 2 for alleviating visual fatigue, it is characterised in that: the haematococcus pluvialis Prawn
Green cellulose content is 6%~9%.
4. the solid beverage according to claim 1 or 2 for alleviating visual fatigue, it is characterised in that: the lutein, maize
Matter is both from marigold flower.
5. the solid beverage according to claim 1 or claim 2 for alleviating visual fatigue, it is characterised in that: the vegetables and fruits ferment powder, is new
Fresh fruit, vegetables are made after everfermentation, pretreatment, freeze-drying, ultraviolet-sterilization.
6. the solid beverage according to claim 1 or claim 2 for alleviating visual fatigue, it is characterised in that: the Fruit powder, being will be fresh
After freeze-drying, preprocessed, quick-frozen, vacuum drying, ultraviolet sterilization process are process fruit.
7. a kind of production method for the solid beverage for alleviating visual fatigue, it is characterised in that: including,
Pretreatment: lutein, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice powder, zeaxanthin, rain life is red
Ball algae, beta carotene sieve with 100 mesh sieve respectively, spare；
Solid beverage is prepared: by the lutein of pretreatment sieving, blueberry powder, D-sorbite, inulin, vegetables and fruits ferment powder, grape juice
Powder, zeaxanthin, haematococcus pluvialis, beta carotene are uniformly mixed according to a certain percentage to get the solid beverage；
Product packing: above-mentioned uniformly mixed solid beverage is packaged processing.
8. alleviating the production method of the solid beverage of visual fatigue according to claim 7, it is characterised in that: the solid beverage
It prepares, wherein in terms of mass fraction, the lutein is 0.01~0.2 part, and the blueberry powder is 1~2 part, the sorbose
Alcohol is 3~5 parts, and the inulin is 1~3 part, and the vegetables and fruits ferment powder is 0.5~2 part, and the grape juice powder is 0.5~2 part,
The zeaxanthin is 0.01~0.05 part, and the haematococcus pluvialis is 0~0.1 part, and the beta carotene is 0~0.3 part.
9. alleviating the production method of the solid beverage of visual fatigue according to claim 7, it is characterised in that: the product point
Dress refers to and solid beverage is encapsulated into resistance oxygen, in the inner bag that blocks water point, be protected from light.
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| CN201810893191 | 2018-08-07 | ||
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| CN114009646A (en) * | 2021-10-27 | 2022-02-08 | 哈尔滨健领医疗科技有限公司 | Solid beverage for protecting eyes and preparation method thereof |
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