CN1104912A - Oral liquid for invigorating kidney and strengthening yang and its production method - Google Patents
Oral liquid for invigorating kidney and strengthening yang and its production method Download PDFInfo
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- CN1104912A CN1104912A CN 94110806 CN94110806A CN1104912A CN 1104912 A CN1104912 A CN 1104912A CN 94110806 CN94110806 CN 94110806 CN 94110806 A CN94110806 A CN 94110806A CN 1104912 A CN1104912 A CN 1104912A
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Abstract
A Chinese medicine for invigorating kidney and strengthening Yang is prepared from 25 Chinese-medicinal materials including pilose antler, American ginseng, astragalus root, gecko, dog's kidney, cynomorium, dodder seed, psoralea fruit, tortoise plastron, prepared rehmannia root, fleece flower root, alismatis rhizome, tangerine peel, liquorice root, etc. its advantages are supplementing each other, no rigidity, reasonable formula, and coordinating compatibility. The product has no toxic or side effect, is safe and reliable, has good medical effects on deficiency of qi and blood and deficiency of kidney yin and yang, such as sexual hypofunction, impotence and spermatorrhea, frequent nocturia, mental fatigue and tiredness, dizziness and amnesia, soreness and weakness of waist and knees and the like, has the cure rate of 65.67 percent, and the total effective rate of 98.34 percent, and is higher than similar products at home and abroad.
Description
The present invention relates to a kind of oral health care medicine, be specially adapted to kidney invigorating and YANG supporting, QI invigorating spermatogenesis, cure mainly diseases such as sexual hypofunction, sexual impotence spermatorrhea, insomnia, nocturia, senile syndrome.
Retrieval shows: oral health care medicine is the focus of strong in recent years font size new drug product development research, and wherein the kind of benefiting vital QI and blood, YIN nourishing and YANG strengthening is no lack of and sees more.Its main component mostly is Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata, Cordyceps, Herba Epimedii etc.That has put on market has Oral Liquid Radix Panacis Quinquefolii, Radix Astragali oral liquid, GUHAN YANGSHENG JING, YANSHENG HUBAO YE, TAIYANGSHEN ORAL LIQUID, clearing heat in the pericardium Chang Chundan, Solenognathus Gecko essence, gives birth to power god or the like.Wherein life source oral liquid, living power god, Solenognathus Gecko essence are all prize-winning at home and abroad.Above-mentioned oral liquid prescription has their own characteristics each, and effect respectively has biased.How further excavate truly have curative effect through proved recipe, particularly stand checking, good reproducibility, proved recipe that curative effect is high, be a job with realistic meaning.
The objective of the invention is to, excavate secret prescription handed down in the family from generation to generation, make full use of Chinese herbal medicine resource, the elaboration of a kind of kidney invigorating and YANG supporting, element culturing fixed folder is provided, take,, alleviate the patient suffering to improve people's body constitution for people.
The object of the present invention is achieved like this: according to being used for the treatment of sexual disorder and low secret prescription handed down in the family from generation to generation, contain 10 flavors in Qing Dynasty's " longevity powder " 20 flavor medicines in the secret recipe, 6 flavors in the strong positive the kidney invigorating ball 15 flavor medicines, 8 flavors in Ginseng Bolus for Tonification's 12 flavor medicines are totally 24 flavors, according to yin yang complementarity, bias toward the theory of tonifying YANG, keep 17 flavors through repetition test research, add 9 herbal medicines again, form Dragon Lord spring oral liquid prescription in conjunction with experience handed down from one's ancestors.
Medicine of the present invention mostly is the gentle agent in the sun, not firm dry property greatly.With Cornu Cervi Pantotrichum, Radix Panacis Quinquefolii is monarch drug, with Gecko, Testis et Pentis Canis, the Radix Astragali, Herba Cynomorii, Herba Cistanches, Semen Cuscutae, the solid fat of benefit, Radix Rehmanniae Preparata, the Radix Polygoni Multiflori is ministerial drug, with Rhizoma Alismatis, Pericarpium Citri Reticulatae is adjuvant drug, and other adds medicines such as Carapax Trionycis, Carapax et Plastrum Testudinis, Semen Juglandis, Rhizoma Curculiginis, Fructus Corni, Fructus Lycii, Radix Glycyrrhizae, Herba Epimedii; Each composition weight umber is: respectively 1 part of Radix Panacis Quinquefolii, Cornu Cervi Pantotrichum, Testis et Pentis Canis, Fructus Corni, Rhizoma Alismatis, Carapax Trionycis, respectively 1.5~1.8 parts of Gecko, Carapax et Plastrum Testudinis, Fructus Psoraleae, Mel, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Rhizoma Curculiginises, respectively 2.5~2.9 parts of Semen Juglandis, Radix Rehmanniae, Semen Allii Tuberosi, Semen Cuscutae, respectively 3.3~3.5 parts of Radix Angelicae Sinensis, the Radix Astragali, shredded meat Rong, Cortex Cinnamomi, Fructus Lycii, Herba Cynomoriis, each 4~5 parts of the Radix Polygoni Multiflori, Herba Epimedii.
The manufacture method of medicine of the present invention is: take alcohol reflux, extract the technology that precipitate with ethanol forms sediment before the water.Medical material is for " one one of Chinese pharmacopoeia nineteen ninety version is recorded product, or the provincial standard collectibles, and its quality standard descends requirement and regulation about item by each.Radix Panacis Quinquefolii, Cornu Cervi Pantotrichum, Gecko, Herba Epimedii, Testis et Pentis Canis, Semen Allii Tuberosi, Fructus Psoraleae, Rhizoma Curculiginis 8 flavor medicated powder are broken into coarse powder, according to the percolation under fluid extract and the extractum item (11 pages of appendix of Chinese Pharmacopoeia nineteen ninety version), make solvent with 80% ethanol, flood after 48 hours, with the about 3~5ml speed of per minute percolation slowly, the collection about 1000ml of liquid that filters, decompression recycling ethanol, and it is standby to be concentrated into the 200ml sealing; Radix Angelicae Sinensis, Cortex Cinnamomi, Pericarpium Citri Reticulatae are extracted volatile oil, and aqueous solution and the medicinal residues after the distillation collect respectively, standby; All the other each medicines are ground into coarse powder, add above-mentioned medicinal residues, mixing decocts with water 3 times, first and second time each 1.5 hours, the 3rd time 1 hour, collecting decoction added the aqueous solution after distilling, filter, it is 1.38~1.40(50~60 ℃ that filtrate is concentrated into relative density) clear paste, put coldly, adding ethanol is 60% to containing the alcohol amount, stir, leave standstill, filter, reclaim ethanol, put cold, add Mel and concentrated solution and volatile oil, stir evenly, regulate pH value at 4.5-5.5, leave standstill, filter, make 1000ml approximately, pack every 10ml.
Product of the present invention is the yellowish-brown supernatant liquid, feeble QI perfume (or spice), the sweet little bitterness of distinguishing the flavor of.Effect with kidney invigorating and YANG supporting, element culturing fixed folder, beneficial blood spermatogenesis.To sexual hypofunction, sexual impotence spermatorrhea, premature ejaculation, nocturia, physical fatigue and lassitude of spirit, dizzy forgetful, soreness of the waist and knees, childhood development are slow good medical function arranged.
Discrimination method: 1. get this product 2ml, put in the test tube, add 0.3% 1,2,3-indantrione monohydrate-n-butyl alcohol-glacial acetic acid solution 1ml, put in the water-bath and heated about 3 minutes, n-butanol layer shows purple.2. get this product 20ml and add sodium chloride and make into saturated solution, add ethanol 20ml, jolting is extracted, and divides and gets ether layer, volatilizes naturally, and the 1% vanillin sulfuric acid solution 1-2 that adds new preparation drips, and drop edge is faded in purple.3. get this product 2ml, add water 2ml, get diluent 2-3 and drip on filter paper, put in the ammonia and smoked 30 seconds, it is yellow that dropping liquid is, displaing yellow fluorescence under the fluorescent lamp.
Medicine of the present invention is compared with similar kidney-nourishing yang-strengthening medicine, the following characteristics of tool: selected medicine mostly is the gentle agent in the moon greatly, and not firm dry property shows unique characteristics on prescription.The researcher LiuBing Fan of the Hunan Province academy of traditional Chinese medicine thinks: " Fang Yuan has certificate, tissue rationally, the compatibility consumption is coordinated, tool equilibrium between yin and yang, qi and blood tonifying and to focus on the congenital foundation be desirable ".
This product is a pure Chinese medicinal preparation, through Beijing, Hunan two famous medical research units of family experimental results demonstrate that this product is without any side effects, and are safe and reliable.Clinical observation 300 examples, to sexual hypofunction, sexual impotence spermatorrhea, mental weariness, soreness of the waist and knees, dizzy forgetful, disease such as childhood development is slow, total effective rate reaches 98.34%, is higher than similar products at home and abroad.Reflection is followed the tracks of in market, and the user is consistent to praise this product curative effect mystery, power is powerful and have no adverse reaction.
For making the auditor darker understanding be arranged, do the detailed introduction of the parties concerned below to the present invention:
One, naming basis
This product has the effect of kidney invigorating and YANG supporting, QI invigorating spermatogenesis, element culturing fixed folder, and kidney deficiency is had good improvement effect, after many patients take this product, and along with the alleviation of the symptom of suffering from a deficiency of the kidney, the spirit multiplication, energy is day by day abundant, seemingly than the life vigor is more arranged before taking medicine.So this product is named as the Dragon Lord spring, meaning i.e. god's the magical effect, the power of dragon, the life in spring, business.Be intended to illustrate this product to kidney-tonifying health-care, improve body body constitution, sexual function improving, help sexual love stirring of love aspect, have magical effectiveness.
Two, prescription foundation
According to theory of Chinese medical science, the relation of sexual disorder and kidney is very close." kidney storing essence ", essence are the base substances that constitutes human body, also are the material bases of the various functional activities of human body.Vital essence is solid, and secret then to keep Human Physiology normal, and consumption hinder then all kinds of pathological changes by give birth to.Smart and blood is supported life each other, and then blood is prosperous for smart foot.So this medicine is cubical basic with " congenital essence comes from kidney, relates to the life prosperity and decline ", according to the Therapeutic Principle of " kidney is tonifying for deficiency syndrome only, can not cut down it and have a surplus ".Kidney storing essence, the residence nephroyin and nephroyang, and be the basic opinion of the person, for sending the cubical foundation of medicine, choose the product counterbalancing YIN through tonifying YANG of sweet temperature QI invigorating such as Cornu Cervi Pantotrichum, Radix Panacis Quinquefolii, the Radix Astragali with " yin yang complementarity biases toward tonifying YANG ".Auxiliary Cornu Cervi Pantotrichum the kidney invigorating thes yang aspect of yang such as Gecko, Testis et Pentis Canis, Herba Cynomorii, Fructus Psoraleae.With the agent nourishing the blood and yin of Radix Rehmanniae Preparata, the sweet profit of the Radix Polygoni Multiflori, spermatogenesis benefit marrow from treating YANG within YIN, reaches the purpose of equilibrium between yin and yang.In addition Rhizoma Alismatis is rushed down the kidney the turbid descending, and Pericarpium Citri Reticulatae is regulated the flow of vital energy, and makes moist and oiliness stagnating, QI invigorating and not being jammed; Radix Glycyrrhizae is sweet slow, coordinating the actions of various ingredients in a prescription, the effect of playing kidney invigorating and YANG supporting, QI invigorating spermatogenesis, element culturing fixed folder altogether.
From the modern pharmacology theory, Radix Ginseng, the Radix Astragali, Cornu Cervi Pantotrichum etc. have the rising peripheral leukocytes and strengthen the function of reticuloendothelial system phagocytic cell, can strengthen the human body immunity; Qi-restoratives medicine strengthens myocardial contraction, blood vessel dilating and hypotensive effect in addition.Radix Ginsengs etc. can improve the ability to work of body, the effect of lessening fatigue.If the qi-restoratives medicine owner is by the human body immunity improving ability, reaching the purpose that gets rid of illness and uncharm, and can regulate and promote substance metabolism and energy metabolisms such as nucleic acid, sugar, protein, the enhancing body ability to work, this treats various deficiency syndrome with tcm clinical practice with qi-restoratives medicine and conforms to.
Three, chemical analysis
Contain tens kinds of compositions such as ginsenoside, flavone, aminoacid, cerebrin, cinnamic aldehyde, hesperidin, betanin, cholesterol, mannitol, osseocolla source, vitamin, lecithin, carnosine, alisol, psoralen, icariine, protein, sugar in the finished product.
Four, pharmacodynamics test
Hunan Inst of Traditional Chinese Medicine central laboratory carries out following pharmacological research: 1, to the influence of mice yang deficiency syndrome; 2, to the gonadal influence of castration male rat; 3, to the influence of mice mating ability; 4, to the influence of immaturity male white rat serum testosterone and sperm count, motility of sperm.The result shows: Dragon Lord spring oral liquid has tangible QI invigorating yang invigorating functions, can improve the yang deficiency syndrome of mice; Can promote the blood ball ketogenesis of immaturity male white rat, promote the vigor of spermatogenesis and raising sperm; The trend that strengthens the mice mating ability is arranged, certain gonadotropic Effect is arranged; Castrated rats sexual accessory gland and organ there is not obvious influence.This medicine has significantly kidney tonifying, essence replenishing, QI invigorating tonifying YANG effect in a word, for clinical practice provide the pharmacology according to.
Five, acute and long term toxicity test
By institute of Chinese materia medica, Hunan Inst of Traditional Chinese Medicine central laboratory, test shows: Dragon Lord spring oral liquid fails to measure LD50 to mouse stomach, and recording maximum tolerated dose with oral liquid stock solution by maximum volume gradation filling stomach in a day is more than the 120ml/kg.This dosage is equivalent to more than 46 times of clinical consumption (pressing body surface area calculates).
Give male and female half and half totally 60 rat oral gavage administrations 30 days, convalescent period observed 15 days, dosage 1.72-3.44g/200g, and the toxic action of Dragon Lord spring oral liquid is not found in aspects such as clinical observation hematology, biochemical, pathology.
Six, clinical setting
1, usage and dosage: oral, a time, twice on the one, morning and evening (medicine) being taken before meal usefulness.Notice that hyperactivity of fire caused by deficiency of YIN, xerostomia red tongue person do not obey contraindication in pregnancy.
2, clinic trial: 1992 in Shaoyang City one the People's Hospital, Shaoyang City two institutes of traditional Chinese medicine try patient's 300 examples altogether, male's 25 examples wherein, women's 46 examples.By age, 18 examples below 20 years old, 132 examples in 20-49 year, 150 examples more than 50 years old.The course of disease 1 year is with 79 interior examples, 1-3 127 examples, 94 examples more than 3 years.
Qi and blood deficiency 128 examples: show as 1. physical fatigue and lassitude of spirit, 2. 3. dizziness and blurred vision has a sleepless night, and 4. pallor is simple and unadorned, 5. light red tongue, 6. thready and weak pulse.In the diagnosis 1.-6. 3.
Kidney yin deficiency of yang type 172 examples show as 1. physical fatigue and lassitude of spirit; 2. soreness of the waist and knees; Ear toot; 4. nocturia; 5. fear cold; 6. hypomnesis; 7. sexual impotence; 8. seminal emission; 9. light red tongue; 10. red tongue lacks tongue; 11. deep-thready pulse; 12. thready and rapid pulse.In the diagnosis 1-9 item 5+9,11 or the 10+12 item.
Its result: 197 examples of clinical symptoms complete obiteration account for 65.67%; Clinical symptoms obviously alleviates or 98 examples more than 2 of disappearing, and accounts for 32.67%; 5 invalid examples account for 1.66%, and total effective rate is 98.34%.
Model case: 1. clock is clear, the man, 36 years old, teacher in the Shaoyang City four, because of spirit tired, lassitude, dizziness and blurred vision, hypomnesis was had a sleepless night 1 year four months, took Dragon Lord spring oral liquid 20 days after totally 40, symptom complete obiteration and fully recovering.
2. Wang, the man, 45 years old, the labor clothes company manager of Shaoyang City commercial bureau, physical fatigue and lassitude of spirit, soreness of the waist and knees, nocturia, sexual impotence 6 years, take 40 of Dragon Lord spring oral liquids after, symptom is clearly better.Obey 60 altogether, symptom complete obiteration and fully recovering.
3. Deng state post, the man, 67 years old, the Loudi was done the cadre of office always, and 60 of this product are taken in dizziness and blurred vision, physical fatigue and lassitude of spirit, soreness of the waist and knees, nocturia, insomnia three and half, recovery from illness.
This medicine is through a large amount of development tests, and Hunan Province bureau of drug administration defends No. 269 literary composition of medicine marking-up with (1992) Hunan and assigns " agreeing the reply that the oral liquid outlet of Dragon Lord spring is sold ".Hunan Province's Chinese medicine Scientific And Technical Intelligence Center retrieval " Chinese pharmacy digest " " medical and health " magazine, the above medical and health scientific and technological achievement compilation of " the 40 years Chinese medicine technological achievements of founding the state " and ministerial level, the conclusion that on October 31st, 1992 drew is not see the report identical with prescription of the present invention arranged.In March, 1993, project of the present invention is listed the national spark project plan in, and Hunan Province Shaoyang City Chinese medicine scientific and technological development industrial corporation goes into operation now.Because product efficacy mystery, outward appearance mouthfeel are good, take more than ten countries and regions such as easy to carry, Hong Kong for export, Taiwan, Macao, Singapore, Thailand, the U.S., Canada.Now prepare to handle the new drug procedure of submitting reports for approval according to Chinese medicine three kind new medicine specification requirements.
Claims (6)
1, a kind of kidney invigorating and YANG supporting medicine belongs to pure Chinese medicinal preparation, the invention is characterized in, with yin yang complementarity, bias toward tonifying YANG for sending the cubical foundation of medicine.Selected medicine mostly is the gentle agent in the moon, not firm dry property greatly in the prescription; Medicine of the present invention contains Cornu Cervi Pantotrichum, Radix Panacis Quinquefolii, Gecko, the Radix Astragali, Herba Cynomorii, Herba Cistanches, Semen Cuscutae, the solid fat of benefit, Radix Rehmanniae Preparata, the Radix Polygoni Multiflori, Rhizoma Alismatis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Carapax et Plastrum Testudinis, Fructus Lycii, Herba Epimedii etc., and product is an oral liquid.
2, medicine according to claim 1, it is characterized in that, each composition weight umber is: respectively 1 part of Radix Panacis Quinquefolii, Cornu Cervi Pantotrichum, Testis et Pentis Canis, Fructus Corni, Rhizoma Alismatis, Carapax Trionycis, respectively 1.5~1.8 parts of Gecko, Carapax et Plastrum Testudinis, Fructus Psoraleae, Mel, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Rhizoma Curculiginises, respectively 2.5~2.9 parts of Semen Juglandis, Radix Rehmanniae, Semen Allii Tuberosi, Semen Cuscutae, respectively 3.3~3.5 parts of Radix Angelicae Sinensis, the Radix Astragali, Herba Cistanches, Cortex Cinnamomi, Fructus Lycii, Herba Cynomoriis, each 4~5 parts of the Radix Polygoni Multiflori, Herba Epimedii.
3, medicine according to claim 1 and 2 is characterized in that, product is yellowish-brown supernatant liquid, feeble QI perfume (or spice), the sweet little bitterness of flavor, and pH value 4.5~5.5 has kidney invigorating and YANG supporting, element culturing fixed folder, the effect of beneficial blood spermatogenesis.
4, medicine according to claim 1 and 2 is characterized in that: this product and 1,2,3-indantrione monohydrate-n-butyl alcohol-glacial acetic acid solution reaction, and n-butanol layer shows purple; This product adds sodium chloride makes into saturated solution, and the jolting that adds diethyl ether divides and gets ether layer, volatilizes, adds 1~2 of 1% vanillin sulfuric acid solution naturally, and drop edge is faded in purple; Get this product dilution drop and put on filter paper in the ammonia smoked 30 seconds, it is yellow that dropping liquid is, displaing yellow fluorescence under the fluorescent lamp.
5, medicine according to claim 1 and 2 is characterized in that: this product has a good medical function to sexual hypofunction, sexual impotence spermatorrhea, premature ejaculation, nocturia, physical fatigue and lassitude of spirit, dizzy forgetful, soreness of the waist and knees, childhood development are slow.
6, claim 1 or 2 described medicine production methods, it is characterized in that, take alcohol reflux, the processes of extracting the precipitate with ethanol shallow lake before the water forms, earlier Radix Panacis Quinquefolii, Cornu Cervi Pantotrichum, Gecko, Herba Epimedii, Testis et Pentis Canis, Semen Allii Tuberosi, Fructus Psoraleae, Rhizoma Curculiginis are ground into coarse powder, collect the liquid of filtering according to the percolation under fluid extract and the extractum item (11 pages of 1990 editions appendix of Chinese Pharmacopoeia), decompression recycling ethanol also concentrates, seals standby; Radix Angelicae Sinensis, Cortex Cinnamomi, Pericarpium Citri Reticulatae are extracted volatile oil, and aqueous solution and the medicinal residues after the distillation collect respectively, standby; All the other each medicated powder are broken into coarse powder, add above-mentioned medicinal residues mixing, decoct with water 3 times, collecting decoction, the aqueous solution that adds after the distillation filters, and it is 1.38~1.40 clear paste that filtrate is concentrated into relative density, put cold, adding ethanol is 60% to containing the alcohol amount, stirs and leaves standstill filtration, reclaims ethanol, putting cold rnning goes into Mel and concentrated solution and volatile oil and stirs evenly, regulate pH value, filter, packing.
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Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1060384C (en) * | 1997-08-01 | 2001-01-10 | 阮可才 | Tianjing Busuiye medicinal liquid and its preparing method |
CN1071122C (en) * | 1997-08-01 | 2001-09-19 | 李余地 | Chinese medicine preparation for treating prospermia and preventing impotence |
EP1504763A4 (en) * | 2002-05-14 | 2006-09-06 | Jianzhong Zhu | Traditional chinese pharmaceutical formulation for treatment of paradentosis, process for preparation and use thereof |
CN100355356C (en) * | 2004-07-06 | 2007-12-19 | 内蒙古农业大学 | Functional fodder additive rich in alpha-linolenic acid |
CN100374138C (en) * | 2006-04-08 | 2008-03-12 | 兰州和盛堂制药有限公司 | Traditional Chinese medicine composition for treating kidney-yang deficiency and deficiency of vital energy and blood, its prepn. process |
CN102134544A (en) * | 2010-11-19 | 2011-07-27 | 苏州市天灵中药饮片有限公司 | Medicinal liquor with efficacy of tonifying yang and nourishing yin |
CN104547963A (en) * | 2015-02-13 | 2015-04-29 | 王学兵 | Medicine for treating male kidney-deficiency waist-knee cold pain and frequent urination and preparation method thereof |
CN105194240A (en) * | 2015-10-30 | 2015-12-30 | 吴小斌 | Traditional Chinese medicine capsules for tonifying yang and invigorating kidney and preparation method of traditional Chinese medicine capsules |
CN108113962A (en) * | 2018-02-23 | 2018-06-05 | 成都中医药大学 | A kind of method for reducing the oral preparation of Chinese traditional medicinal astringent taste containing polyphenol |
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1994
- 1994-01-07 CN CN 94110806 patent/CN1104912A/en active Pending
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1060384C (en) * | 1997-08-01 | 2001-01-10 | 阮可才 | Tianjing Busuiye medicinal liquid and its preparing method |
CN1071122C (en) * | 1997-08-01 | 2001-09-19 | 李余地 | Chinese medicine preparation for treating prospermia and preventing impotence |
EP1504763A4 (en) * | 2002-05-14 | 2006-09-06 | Jianzhong Zhu | Traditional chinese pharmaceutical formulation for treatment of paradentosis, process for preparation and use thereof |
CN100355356C (en) * | 2004-07-06 | 2007-12-19 | 内蒙古农业大学 | Functional fodder additive rich in alpha-linolenic acid |
CN100374138C (en) * | 2006-04-08 | 2008-03-12 | 兰州和盛堂制药有限公司 | Traditional Chinese medicine composition for treating kidney-yang deficiency and deficiency of vital energy and blood, its prepn. process |
CN102134544A (en) * | 2010-11-19 | 2011-07-27 | 苏州市天灵中药饮片有限公司 | Medicinal liquor with efficacy of tonifying yang and nourishing yin |
CN104547963A (en) * | 2015-02-13 | 2015-04-29 | 王学兵 | Medicine for treating male kidney-deficiency waist-knee cold pain and frequent urination and preparation method thereof |
CN105194240A (en) * | 2015-10-30 | 2015-12-30 | 吴小斌 | Traditional Chinese medicine capsules for tonifying yang and invigorating kidney and preparation method of traditional Chinese medicine capsules |
CN108113962A (en) * | 2018-02-23 | 2018-06-05 | 成都中医药大学 | A kind of method for reducing the oral preparation of Chinese traditional medicinal astringent taste containing polyphenol |
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