CN110478349A - 一种伤口护理用敷料及其制备方法 - Google Patents
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
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- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/07—Stiffening bandages
- A61L15/08—Stiffening bandages containing inorganic materials, e.g. plaster of Paris
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/07—Stiffening bandages
- A61L15/10—Stiffening bandages containing organic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
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- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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Abstract
Description
组别 | 样本量(只) | 伤口数量 | 感染伤口数量 | 伤口愈合时间(d) |
实施例1 | 5 | 10 | 2 | 16.30±0.95*** |
实施例6 | 5 | 10 | 4 | 18.30±0.95*** |
对比例1 | 5 | 10 | 10 | 29.80±3.55* |
对比例2 | 5 | 10 | 3 | 20.60±1.96** |
对比例3 | 5 | 10 | 1 | 19.2±1.03*** |
对比例4 | 5 | 10 | 8 | 25.20±3.71 |
莫比罗星 | 5 | 10 | 5 | 21.3±2.67* |
Claims (10)
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CN201910896902.0A CN110478349B (zh) | 2019-09-23 | 2019-09-23 | 一种伤口护理用敷料及其制备方法 |
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CN201910896902.0A CN110478349B (zh) | 2019-09-23 | 2019-09-23 | 一种伤口护理用敷料及其制备方法 |
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CN110478349A true CN110478349A (zh) | 2019-11-22 |
CN110478349B CN110478349B (zh) | 2022-11-15 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111803697A (zh) * | 2020-07-16 | 2020-10-23 | 太原理工大学 | 一种载药海藻酸钠/明胶复合水凝胶型创可贴的制备方法 |
CN116808141A (zh) * | 2023-06-21 | 2023-09-29 | 浙江医鼎医用敷料有限公司 | 一种伤口护理软膏及其制备方法 |
Citations (3)
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CN103520767A (zh) * | 2013-10-28 | 2014-01-22 | 山东赛克赛斯药业科技有限公司 | 一种抗菌促愈水凝胶敷料及其制备方法 |
CN105832817A (zh) * | 2016-05-11 | 2016-08-10 | 深圳市太生源健康产业有限公司 | 吡咯喹啉醌在治疗烧伤、烫伤和创伤方面的应用 |
WO2018209601A1 (zh) * | 2017-05-17 | 2018-11-22 | 南京舒鹏生物科技有限公司 | 吡咯喹啉醌衍生物及其组合物 |
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2019
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103520767A (zh) * | 2013-10-28 | 2014-01-22 | 山东赛克赛斯药业科技有限公司 | 一种抗菌促愈水凝胶敷料及其制备方法 |
CN105832817A (zh) * | 2016-05-11 | 2016-08-10 | 深圳市太生源健康产业有限公司 | 吡咯喹啉醌在治疗烧伤、烫伤和创伤方面的应用 |
WO2018209601A1 (zh) * | 2017-05-17 | 2018-11-22 | 南京舒鹏生物科技有限公司 | 吡咯喹啉醌衍生物及其组合物 |
Non-Patent Citations (3)
Title |
---|
SMIDT CR等: "DOES THE INTESTINAL MICROFLORA SYNTHESIZE PYRROLOQUINOLINE QUINONE", 《BIOFACTORS》 * |
UMEZAWA K等: "A Novel pyrroloquinoline Quinone-Dependent-2-Keto-D-Glucose Dehydrogenase from Pseudomonas aureofaciense", 《JOURNAL OF BACTERIOLOGY》 * |
李皓恒: "吡咯喹啉醌对放创性皮肤损伤促愈合研究", 《中华放射医学与防护杂志》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111803697A (zh) * | 2020-07-16 | 2020-10-23 | 太原理工大学 | 一种载药海藻酸钠/明胶复合水凝胶型创可贴的制备方法 |
CN116808141A (zh) * | 2023-06-21 | 2023-09-29 | 浙江医鼎医用敷料有限公司 | 一种伤口护理软膏及其制备方法 |
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Inventor after: Dong Xiaohong Inventor after: Li Boqian Inventor after: Li Xiaoqing Inventor after: Liu Daxu Inventor after: Peng Yubo Inventor after: Wang Yueyang Inventor after: Fu Lin Inventor after: Wang Jingjiao Inventor after: Zhang Zihan Inventor after: Li Qingwei Inventor after: Zhang Zhengyi Inventor after: Yang Defang Inventor before: Dong Xiaohong Inventor before: Li Boqian Inventor before: Li Xiaoqing Inventor before: Liu Daxu Inventor before: Peng Yubo Inventor before: Wang Yueyang Inventor before: Fu Lin Inventor before: Wang Jingjiao Inventor before: Zhang Zihan Inventor before: Li Qingwei Inventor before: Zhang Zhengyi Inventor before: Yang Defang |
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Application publication date: 20191122 Assignee: Jiangsu Yu Yuan Pharmaceutical Technology Co.,Ltd. Assignor: HEILONGJIANG University OF CHINESE MEDICINE Contract record no.: X2023980034910 Denomination of invention: A wound care dressing and its preparation method Granted publication date: 20221115 License type: Common License Record date: 20230420 |