CN110441510A - Immunochromatographytest test kit - Google Patents

Immunochromatographytest test kit Download PDF

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Publication number
CN110441510A
CN110441510A CN201910713964.3A CN201910713964A CN110441510A CN 110441510 A CN110441510 A CN 110441510A CN 201910713964 A CN201910713964 A CN 201910713964A CN 110441510 A CN110441510 A CN 110441510A
Authority
CN
China
Prior art keywords
immune chromatography
test kit
test paper
box body
immunochromatographytest
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910713964.3A
Other languages
Chinese (zh)
Inventor
霍雨佳
谷娟
刘超怡
陈青阁
周龙飞
李明阳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Huanghe Science and Technology College
Original Assignee
Huanghe Science and Technology College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huanghe Science and Technology College filed Critical Huanghe Science and Technology College
Priority to CN201910713964.3A priority Critical patent/CN110441510A/en
Publication of CN110441510A publication Critical patent/CN110441510A/en
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures

Abstract

The invention belongs to field of medical examination, specifically disclose a kind of immunochromatographytest test kit.The present invention includes box body, immune chromatography test paper is set in box body, the outer wall of box body opens up observation window, time showing ring is arranged in one end of immune chromatography test paper, the other end of immune chromatography test paper is located at the outer wall setting sealing strip of box body, immune chromatography test paper is connected to one end of main hydraulic pipe by sealing strip, and the other end of main hydraulic pipe is connected to pipette and pressure auxiliary ball is arranged between main hydraulic pipe and pipette.Kit soakage provided by the invention is controllable, directly can check time of measuring by time showing ring, not need other timing tools.

Description

Immunochromatographytest test kit
Technical field
The invention belongs to field of medical examination, have and are related to a kind of immunochromatographytest test kit.
Background technique
Immunochromatographytest test kit in the prior art, e.g., [Chinese utility model] CN201520271542.2 are a kind of Immunochromatographytest test kit, disclosed, immune chromatography test paper is the multi-layer film structure with desiccant bottom, including bottom plate, And paste sample pad, bonding pad, chromatographic film and water absorption pad with successively overlapping on bottom plate;Sample pad, bonding pad, chromatographic film and suction It is closely coupled between each tunic of these membrane structures of water cushion, it is least partially overlapped;Chromatographic film is coated with the detection line being parallel to each other And nature controlling line, detection line is close to bonding pad side, and nature controlling line is far from bonding pad and close to water absorption pad side;It is pasted under the bottom plate There is desiccant, fiber desiccant can be used in desiccant.Disclosed above is a kind of conventional technique of immunochromatographytest test kit Situation, although the immunochromatographytest test kit can satisfy the portion requirements in market, the immunochromatographytest test kit Have a single function, measure it is not accurate enough, it is especially not competent to need precisely demanding immunochromatography inspection there are more error It surveys.
Summary of the invention
The purpose of the present invention is to provide a kind of immunochromatographytest test kits.
Based on above-mentioned purpose, the present invention is adopted the following technical scheme that:
A kind of immunochromatographytest test kit, including box body, box body is interior to be arranged immune chromatography test paper, and the outer wall of box body opens up Time showing ring is arranged in one end of observation window, immune chromatography test paper, and the other end of immune chromatography test paper is located at the outer wall of box body Sealing strip is set, and immune chromatography test paper is connected to one end of main hydraulic pipe by sealing strip, and the other end of main hydraulic pipe is connected to pipette And pressure auxiliary ball is set between main hydraulic pipe and pipette.
Further, the feed liquor port setting annular suction inlet outstanding of the pipette, the suction inlet inner wall fix one Enclose blocking ring.
Further, the blocking ring is specifically water swelling rubber.
Further, the pressure auxiliary ball is that capsule is spherical, and the side of pressure auxiliary ball is semiclosed cover structure, should half envelope It closes cover structure to be made of elastic material, the other side of pressure auxiliary ball is the semiclosed cover structure with through-hole, this has logical The semiclosed cover structure in hole is made of not flexible plastic material.
Further, the semiclosed cover structure is specifically elastomeric material, the semiclosed cover structure tool of the through-hole Body is polyethylene material.
Further, the time showing ring includes the continuous conduit of ring week winding, if being distributed setting on above-mentioned pipeline The dry test block reacted with liquid to be detected.
Further, it is coated on immune chromatography test paper on the test block and is immunoreacted identical substance, which presses It is smeared according to numerical switch.
Beneficial effect
The application, which obtains solution to be detected by sealing strip, main hydraulic pipe and pipette, can completely cut off air contact, in addition seal Closing item, main hydraulic pipe and pipette specification is that specifically, the solution adhered to is also to quantify or controllably, can control acquisition The prepare liquid scale of construction;Suction inlet, then due to water swelling, and then suction inlet can be sealed completely in the prepare liquid rear plugging ring for drawing specific quantity It is stifled, and then other testing liquids can be prevented to flow into influence;Realize the limit space that quantitative pressing pressure auxiliary ball is pressed, And then it can control the maximum value of negative pressure, and then can control the soakage for the suction inlet for surveying liquid by its connection;User can be with Time of measuring is directly checked by time showing ring, without other timing tools.
Detailed description of the invention
Present invention will be further explained below with reference to the attached drawings and examples.
Fig. 1 is the Structure Figure of immunochromatographytest test kit in the prior art;
Fig. 2 is the Structure Figure of immunochromatographytest test kit in the prior art;
Fig. 3 is the overall structure figure of the embodiment of the present application;
Fig. 4 is the structural schematic diagram of the embodiment of the present application pipette;
Fig. 5 is the structural schematic diagram after the blocking ring water swelling of the embodiment of the present application pipette;
Fig. 6 is the pressure auxiliary ball structural schematic diagram of the embodiment of the present application
Fig. 7 is the structural schematic diagram of the time showing ring of the embodiment of the present application
Specific embodiment
As shown in Figs. 1-2, immunochromatographytest test kit in the prior art, [Chinese utility model] A kind of immunochromatographytest test kit of CN201520271542.2, disclosed, immune chromatography test paper is with desiccant bottom 1 Multi-layer film structure, including bottom plate 2, and successively sample pad 3, bonding pad 4, chromatographic film 5 and water absorption pad are pasted in overlap joint ground on a base plate 2 6;Sample pad 3,6 these membrane structures of bonding pad 4, chromatographic film 5 and water absorption pad each tunic between it is closely coupled, it is at least partly heavy It is folded;Chromatographic film 5 is coated with the detection line 7 being parallel to each other and nature controlling line 8, and detection line is close to bonding pad side, and nature controlling line is far from knot Close pad and close water absorption pad side;It is pasted with desiccant 1 under the bottom plate 2, fiber desiccant can be used in desiccant.Further Say, immune chromatography test paper is strip, and glass film or polyester film can be used in sample pad 3, and front end is pasted on bottom plate front end, End lap is on bonding pad 4;Bonding pad 4 includes film matrix, and is evenly applied to the detected material mark of the film matrix surface The immune coating of note, positioned at sample pad 3 and chromatographic film 5 between, front end overlaps and is pasted on bottom plate 2, and rear end is from chromatographic film 5 Extend certain length above front end;The front end of chromatographic film is inserted between bonding pad and bottom plate and is bonded on bottom plate;Water suction Pad 6 is overlapped in chromatographic film 5, and is pasted on the rear end of bottom plate 2;The detection line 7 and nature controlling line 8 are respectively corresponding be coated in should Two parallel bands in chromatographic film 5, respectively in combination with the immune coating of detection substance markers, glass film or polyester is can be used in bonding pad Nitrocellulose filter can be used in film, chromatographic film.Specifically, as shown in Fig. 2, well 10 and air hole 12 are through shell 9 Through-hole corresponds to the sample pad of immune chromatography test paper immediately below well 10, corresponds to immune chromatography test paper immediately below air hole 12 Water absorption pad, detection 11 be through-hole;The detection line and nature controlling line of immune chromatography test paper are corresponded to immediately below detection window 11.
A kind of typical immunochromatographytest test kit in the prior art is disclosed in above-mentioned technology, is tested in the technology Liquid is difficult to most accurate quantitative determination in test, in addition general testing liquid and immune chromatography test paper in measurement It can directly be contacted by air and also influence whether measurement effect, so there are more mistakes for the immunochromatographytest test kit Difference, in addition to this, which, which can not be competent at, has the immunochromatography precisely required detection to measurement.
Such as Fig. 3, one embodiment of the application includes box body a1, and immune chromatography test paper a2, box body a1 is arranged in box body a1 Outer wall open up observation window a3, time showing ring a5 is arranged in one end of immune chromatography test paper a2, and immune chromatography test paper a2 is in addition Outer wall setting the sealing strip a4, immune chromatography test paper a2 that one end is located at box body a1 are connected to the one of main hydraulic pipe a6 by sealing strip a4 End, the other end connection pipette a8 and setting pressure auxiliary ball a7 between main hydraulic pipe a6 and pipette a8 of main hydraulic pipe a6; The immune chromatography test paper a2 of the application is connected to one end of main hydraulic pipe a6, the other end of main hydraulic pipe a6 by sealing strip a4 in implementation It is connected to pipette a8, the application, which obtains solution to be detected by sealing strip, main hydraulic pipe and pipette, can completely cut off air contact, separately Outer closure item, main hydraulic pipe and pipette specification are that specifically, the solution adhered to is also to quantify or controllably, can control and adopt The prepare liquid scale of construction of collection.
When it is implemented, a kind of immunochromatographytest test kit, as the feed liquor port of Fig. 4-5, the pipette a8 are set Annular suction inlet a10 outstanding is set, the suction inlet a10 inner wall fixes a circle blocking ring a9;The blocking ring a9 specifically absorbs water swollen Swollen rubber;When implementation, subsequent handling is specifically absorbed and flowed into testing liquid by suction inlet a10, suction inlet a10 is drawing spy Quantitative prepare liquid rear plugging ring a9 can be blocked suction inlet a10, and then can prevent other completely then due to water swelling Testing liquid flow into influence, avoid influence detect result.
In implementation, if Fig. 6, the pressure auxiliary ball a7 are that capsule is spherical, the side of pressure auxiliary ball a7 is semiclosed cover Structure a11, the semiclosed cover structure a11 are made of elastic material, and the other side of pressure auxiliary ball a7 is half with through-hole Cover structure a12 is closed, there is the semiclosed cover structure a12 of through-hole to be made of not flexible plastic material for this;It is described semiclosed Cover structure a11 is specifically elastomeric material, and the semiclosed cover structure a12 of the through-hole is specifically polyethylene material;Implement In, operator's press pressure auxiliary ball a7 can form negative pressure and then by testing liquid by its connection in its elastic recovery process Suction inlet a10 sucking, the specification material tool of above-mentioned semiclosed cover structure a11 or the semiclosed cover structure a12 with through-hole is Specifically, it may be implemented the limit space that the quantitative above-mentioned pressure auxiliary ball a7 of control is pressed in this way, and then can be with The maximum value of negative pressure is controlled, and then can control the soakage for the suction inlet a10 for surveying liquid by its connection.
In implementation, if Fig. 7, the time showing ring a5 include the continuous conduit wound in ring week, divide on above-mentioned pipeline Several test blocks reacted with liquid to be detected are arranged in cloth;It is coated on the test block on immune chromatography test paper a2 for being immunized Identical substance is reacted, which smears according to numerical switch;In an implementation, it is different to be diffused into time showing ring a5 for testing liquid Continuous conduit on time be it is different, the closer continuous conduit in trajectory distance liquid source then spread it is more early, it is no It is then more late, since the speed of the diffusion is certain so testing liquid reaches not from beginning when reaching immune chromatography test paper a2 to it With the test block time be also different, and the time be it is predictable, in this way different test blocks with it is to be measured The reaction time of liquid can also indicate that testing liquid reaches the time of immune chromatography test paper a2, so smearing according to numerical switch Test block can also directly display liquid reach immune chromatography test paper a2 time, user can be direct in this way Time of measuring is checked by time showing ring a5, without other timing tools.
Device embodiments described above are only schematical, can select portion therein according to the actual needs Point or whole component realize the purpose of present embodiment scheme.Those of ordinary skill in the art are not making the creative labor In the case where, it can it understands and implements.

Claims (7)

1. a kind of immunochromatographytest test kit, which is characterized in that including box body, immune chromatography test paper, box body is arranged in box body Outer wall open up observation window, time showing ring is arranged in one end of immune chromatography test paper, and the other end of immune chromatography test paper is located at Sealing strip is arranged in the outer wall of box body, and immune chromatography test paper is connected to one end of main hydraulic pipe, the other end of main hydraulic pipe by sealing strip It is connected to pipette and pressure auxiliary ball is set between main hydraulic pipe and pipette.
2. a kind of immunochromatographytest test kit as described in claim 1, which is characterized in that the liquid feeding end of the pipette Mouth setting annular suction inlet outstanding, the suction inlet inner wall fix a circle blocking ring.
3. a kind of immunochromatographytest test kit as described in claim 1, which is characterized in that the blocking ring is specifically to absorb water Expanded rubber.
4. a kind of immunochromatographytest test kit as described in claim 1, which is characterized in that the pressure auxiliary ball is capsule Spherical shape, the side of pressure auxiliary ball are semiclosed cover structures, which is made of elastic material, pressure auxiliary ball Other side is the semiclosed cover structure with through-hole, this has the semiclosed cover structure of through-hole by not flexible plastic material It constitutes.
5. a kind of immunochromatographytest test kit as claimed in claim 4, which is characterized in that the semiclosed cover structure is specific It is elastomeric material, the semiclosed cover structure of the through-hole is specifically polyethylene material.
6. a kind of immunochromatographytest test kit as described in claim 1, which is characterized in that the time showing ring includes Ring week winding continuous conduit, several test blocks reacted with liquid to be detected are arranged in distribution on above-mentioned pipeline.
7. a kind of immunochromatographytest test kit as claimed in claim 6, which is characterized in that be coated on the test block Identical substance is immunoreacted on immune chromatography test paper, which smears according to numerical switch.
CN201910713964.3A 2019-08-02 2019-08-02 Immunochromatographytest test kit Pending CN110441510A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910713964.3A CN110441510A (en) 2019-08-02 2019-08-02 Immunochromatographytest test kit

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910713964.3A CN110441510A (en) 2019-08-02 2019-08-02 Immunochromatographytest test kit

Publications (1)

Publication Number Publication Date
CN110441510A true CN110441510A (en) 2019-11-12

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112858273A (en) * 2021-01-13 2021-05-28 梅里医疗科技(洋浦)有限责任公司 Detection kit for intelligent hospital, adaptive detection device and detection method

Citations (8)

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Publication number Priority date Publication date Assignee Title
JPH07134123A (en) * 1993-09-17 1995-05-23 Nissho Corp Container for diagnosis
CN104142392A (en) * 2014-08-18 2014-11-12 深圳市领治医学科技有限公司 Trace sample test paper
CN105866419A (en) * 2016-06-14 2016-08-17 中州大学 Fluorescence immunoassay chromatography test strip for detecting vomitoxin
CN107132352A (en) * 2017-07-07 2017-09-05 济南齐鲁医学检验有限公司 A kind of microalbumin creatinine ratio(ARC)Detection means
CN107970045A (en) * 2017-12-04 2018-05-01 山西农业大学 Intestinal contents negative pressure Autosampler
CN208506051U (en) * 2018-06-07 2019-02-15 杭州安旭科技有限公司 A kind of timing Test paper and immunochromatography timing detection device
CN208672648U (en) * 2018-08-13 2019-03-29 深圳市绿诗源生物技术有限公司 A kind of morphine rapid detection card
CN109620299A (en) * 2019-01-29 2019-04-16 上海安翰医疗技术有限公司 A kind of alimentary canal multiposition liquid sampling device for biopsy

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07134123A (en) * 1993-09-17 1995-05-23 Nissho Corp Container for diagnosis
CN104142392A (en) * 2014-08-18 2014-11-12 深圳市领治医学科技有限公司 Trace sample test paper
CN105866419A (en) * 2016-06-14 2016-08-17 中州大学 Fluorescence immunoassay chromatography test strip for detecting vomitoxin
CN107132352A (en) * 2017-07-07 2017-09-05 济南齐鲁医学检验有限公司 A kind of microalbumin creatinine ratio(ARC)Detection means
CN107970045A (en) * 2017-12-04 2018-05-01 山西农业大学 Intestinal contents negative pressure Autosampler
CN208506051U (en) * 2018-06-07 2019-02-15 杭州安旭科技有限公司 A kind of timing Test paper and immunochromatography timing detection device
CN208672648U (en) * 2018-08-13 2019-03-29 深圳市绿诗源生物技术有限公司 A kind of morphine rapid detection card
CN109620299A (en) * 2019-01-29 2019-04-16 上海安翰医疗技术有限公司 A kind of alimentary canal multiposition liquid sampling device for biopsy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112858273A (en) * 2021-01-13 2021-05-28 梅里医疗科技(洋浦)有限责任公司 Detection kit for intelligent hospital, adaptive detection device and detection method

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Application publication date: 20191112

RJ01 Rejection of invention patent application after publication