CN212533003U - Respiratory system infects integrative device of viroid sample collection detection - Google Patents
Respiratory system infects integrative device of viroid sample collection detection Download PDFInfo
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- CN212533003U CN212533003U CN202020618429.8U CN202020618429U CN212533003U CN 212533003 U CN212533003 U CN 212533003U CN 202020618429 U CN202020618429 U CN 202020618429U CN 212533003 U CN212533003 U CN 212533003U
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Abstract
The utility model discloses a respiratory infects a virus sample and gathers integrative device of detection, including sample pipe and the test tube that adopts transparent material to make, the open-top of sample pipe is equipped with the lid, and open the bottom has through-hole A, and the top of test tube is sealed and is opened there is through-hole B, is equipped with test paper along vertical direction on the pipe wall of test tube, and through-hole A passes through the pipe connection with through-hole B, and the pipeline extends to in the test tube and the end is located the test paper below, is located to install the switch module who is used for putting through or breaking off sample pipe and test tube on through-hole A and through-hole B's the pipeline. The utility model discloses a pipeline is with sample pipe and test tube intercommunication, can make the mixed liquid of sample directly get into in the test tube and detect through test paper, need not the secondary and uncap and avoid producing the danger of aerosol pollution and reduce the possibility of propaganda once more.
Description
Technical Field
The utility model relates to a colloidal gold detection area is based on and relates to a respiratory infects viroid sample and gathers integrative device of detection.
Background
At present, the detection mode which is more clinically applied is fluorescence quantitative detection of virus nucleic acid, although the detection sensitivity and specificity are good, the detection mode needs professional laboratory equipment and personnel and is not suitable for large-area screening of a basic layer, and the colloidal gold antibody detection mode meets the requirements of rapidness, cheapness and simple operation needed by field and basic layer detection. At present, a common colloidal gold detection mode is that a collection tube and detection test paper are separated, a cover needs to be opened again for detection after a sample is collected, and the danger of aerosol pollution and the possibility of secondary propagation are hidden by the secondary cover opening mode.
Disclosure of Invention
An object of the utility model is to provide a respiratory infects viroid sample and gathers and detect integrative device, the device's collection with detect integrated together, need not the secondary and uncap and can obtain the testing result.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the utility model provides an integrative device of respiratory infection viroid sample collection detection, including sample pipe and the test tube that adopts transparent material to make, the open-top of sample pipe is equipped with the lid, open the bottom has through-hole A, the top of test tube is sealed and is opened there is through-hole B, be equipped with test paper along vertical direction on the pipe wall of test tube, through-hole A passes through the pipe connection with through-hole B, the pipeline extends to in the test tube and the end is located the test paper below, be located and install the switch module that is used for putting through or breaking off sample pipe and test tube on through-hole A and through-hole B's the pipeline.
Furthermore, the pipeline is a hose, the switch assembly is an air bag wrapped on the pipeline positioned in the through hole A and the through hole B, the air bag is filled with high-pressure gas, and the through hole A is communicated with the through hole B by deflating the air bag.
Furthermore, a supporting plate is arranged between the sample tube and the detection tube, and a bevel gear part is arranged on one side, close to the air bag, of the supporting plate.
Furthermore, the pipeline is a hard pipe and is divided into two sections, one section is connected with the through hole A, and the other section is connected with the through hole B; the switch assembly comprises a circular chute formed in the top of the detection tube and a rotary cylinder with openings at two ends capable of sleeving the sample tube and the detection tube, the bottom of the pipeline connected with the through hole A is located in the circular chute, the through hole B is located at the bottom of the circular chute, and the bottom of the pipeline connected with the through hole A is communicated with the through hole B by rotating the sample tube.
Further, a sealing ring is installed in the circular sliding groove.
Further, the detection test paper sequentially comprises a sample pad, a colloidal gold pad, a nitrocellulose membrane and a water absorption pad from bottom to top, and the nitrocellulose membrane is provided with a detection line and a quality control line.
The utility model discloses following beneficial effect has:
(1) the sample tube is communicated with the detection tube through the pipeline, so that the sample mixed liquid can directly enter the detection tube to be detected through the detection test paper, the danger of aerosol pollution is avoided without secondary cover opening, and the possibility of secondary propagation is reduced;
(2) by arranging the switch assembly on the pipeline, the sample liquid can be stored in the sample tube in advance, so that the operation steps during detection are reduced;
(3) the test paper is provided with a detection line and a quality control line, so that the detection result can be visually checked.
Drawings
Fig. 1 is a schematic structural diagram of embodiment 1 of the present invention.
Fig. 2 is a schematic view of the structure of the test paper of the present invention.
Fig. 3 is a schematic structural view of embodiment 2 of the present invention.
Fig. 4 is a schematic top view of a detection tube according to embodiment 2 of the present invention.
The labels in the figure are: 10. a sample tube; 11. a cover body; 20. a detection tube; 21. a through hole B; 30. detecting test paper; 31. a sample pad; 32. a colloidal gold pad; 33. a nitrocellulose membrane; 34. a water absorbent pad; 35. detecting lines; 36. a quality control line; 40. a pipeline; 41. a pipeline A; 42. a pipeline B; 50. an air bag; 51. a support plate; 52. a bevel gear member; 60. a rotary drum; 61. a circular chute.
Detailed Description
Example 1
As shown in fig. 1, the respiratory infection viroid sample collection and detection integrated device provided in this embodiment includes a sample tube 10, a detection tube 20, and a conduit 40 for communicating the sample tube 10 and the detection tube 20. The sample tube 10 and the detection tube 20 are transparent tubes made of medical polypropylene materials; the top of the sample tube 10 is open and provided with a cover body 11, and the bottom of the sample tube is provided with a through hole A; the inner wall of the detection tube 20 is provided with the detection test paper 30, the detection test paper 30 can be fixed on the inner wall of the detection tube 20 by using an adhesive, or can be fixed on the inner wall of the detection tube 20 by arranging a limit clamp inside a slide way, the top of the detection tube 20 is provided with a through hole B21, the through hole A is connected with the through hole B21 through a hose, the tail end of the hose extends to the bottom of the detection tube 20, the hose between the through hole A and the through hole B21 is provided with an air bag 50, and compressed air is filled into the air bag 50 to enable the pressure of the air bag 50 to be higher than the pressure in the hose, so that sample liquid can be added into the sample tube 10 in advance, and the sample liquid cannot flow into the detection. The reduction of gas in the bladder 50 may result in a pressure lower than the pressure in the hose, which may be accomplished by providing a pressure relief valve in the bladder 50 or by puncturing the bladder 50 with a sharp object. Specifically, the present embodiment adopts a supporting plate 51 installed between the sample tube 10 and the detecting tube 20, the sample tube 10 and the detecting tube 20 can be connected, a bevel gear member 52 can be further provided at a side of the supporting plate 51 close to the air cell 50, a certain distance is provided between a tip of the bevel gear member 52 and the air cell 50, and the air cell 50 can be deflated by applying a certain force to the supporting plate 51 to make the tip of the bevel gear member 52 puncture the air cell 50.
As shown in fig. 2, the detection test paper 30 includes a sample pad 31, a colloidal gold pad 32, a nitrocellulose membrane 33 and a water absorption pad 34, which are sequentially disposed from bottom to top, the colloidal gold pad 32 is provided with an antibody labeled with colloidal gold, the nitrocellulose membrane 33 is provided with a detection line 35 and a quality control line 36, and the detection line 35 and the quality control line 36 are both coated with detection antibodies.
The detection principle of the detection test paper 30 of the embodiment is similar to that of a pregnancy test stick, and two macroscopic red reaction lines are respectively formed on the virus carrier detection line 35 and the quality control line 36; otherwise, only one red reaction line appears on the control line 36.
When the device is used, a cotton swab or a collection swab is used for collecting a nasopharyngeal sample of a detected person, after collection, the cover body 11 of the sample tube 10 is opened, the cotton swab or the collection swab is placed into the sample tube 10 filled with preservation liquid, the cover body 11 of the sample tube 10 is covered, the cover body is gently shaken, after the collected sample and the preservation liquid are fully mixed, a force towards the air bag 50 is applied to the supporting plate 51, the tip part of the conical tooth part 52 punctures the air bag 50, the liquid in the sample tube 10 enters the detection tube 20 through the pipeline 40, the sample pad 31 contacts the sample mixed liquid and then reaches the detection line 35 and the quality control line 36 upwards under the action of absorbent paper, the detection result is displayed through the appearing indication lines, and two red reaction lines which can be seen by naked eyes are respectively formed on the detection line 35 and the quality control line 36 of a virus carrier; otherwise, only one red reaction line appears on the control line 36.
Example 2
As shown in fig. 3 and 4, the respiratory infection viroid sample collection and detection integrated device provided in this embodiment includes a sample tube 10, a detection tube 20, and a conduit 40 communicating the sample tube 10 and the detection tube 20. The sample tube 10 and the detection tube 20 are transparent tubes made of medical polypropylene materials; the top of the sample tube 10 is open and provided with a cover body 11, and the bottom of the sample tube is provided with a through hole A; the inner wall of the detection tube 20 is provided with a detection test paper 30, the detection test paper 30 can be fixed on the inner wall of the detection tube 20 by using an adhesive, or can be fixed on the inner wall of the detection tube 20 by arranging a limit card inside the slideway, and the top of the detection tube 20 is provided with a through hole B21. The pipeline 40 is a hard pipe and comprises two ends, a pipeline A41 and a pipeline B42, the pipeline A41 is communicated with the through hole A and is positioned at the bottom of the sample pipe 10, the pipeline B42 is communicated with the through hole B21 and is positioned in the detection pipe 20, and the tail end of the pipeline B42 is positioned below the detection test paper 30; the sample tube 10 is connected with the detection tube 20 through a rotary cylinder 60, and the bottom of the sample tube 10 and the top of the detection tube 20 can be respectively and rotatably sleeved on openings at two ends of the rotary cylinder 60; the top of the detecting tube 20 is provided with a circular sliding groove 61, the end of the pipeline a41 is located in the circular sliding groove 61, a sealing ring for sealing is installed in the circular sliding groove 61 to ensure that the end of the pipeline a41 can be blocked, so that the liquid does not flow down, the through hole B21 is also located in the circular sliding groove 61, and the pipeline a41 is communicated with the through hole B21 by rotating the sample tube 10 or the detecting tube 20, so that the sample liquid in the sample tube 10 can enter the detecting tube 20 through the pipeline 40 for detection.
When the device is used, a cotton swab or a collection swab is used for collecting nasopharyngeal samples of a detected person, after collection, the cover body 11 of the sample tube 10 is opened, the cotton swab or the collection swab is placed into the sample tube 10 filled with preservation liquid, the cover body 11 of the sample tube 10 is covered, the sample tube 10 is gently shaken, after the collected samples and the preservation liquid are fully mixed, the sample tube 10 or the detection tube 20 is rotated to enable the pipeline 40A to be communicated with the through hole B21, liquid in the sample tube 10 enters the detection tube 20 through the pipeline 40, the sample pad 31 contacts the sample mixed liquid and then upwards reaches the detection line 35 and the quality control line 36 under the action of absorbent paper, the detection result is displayed through the appearing indication lines, and two macroscopic red reaction lines are respectively formed on the virus carrier detection line 35 and the quality control line 36; otherwise, only one red reaction line appears on the control line 36.
The above is only the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any modification and replacement based on the technical solution and the utility model should be covered in the protection scope of the present invention.
Claims (6)
1. The utility model provides an integrative device of respiratory system infection viroid sample collection detection which characterized in that: including sample pipe (10) and detecting tube (20) that adopt transparent material to make, the open-top of sample pipe (10) is equipped with lid (11), open the bottom has through-hole A, the top of detecting tube (20) is sealed and is opened through-hole B (21), be equipped with test paper (30) along vertical direction on the pipe wall of detecting tube (20), through-hole A passes through pipeline (40) with through-hole B (21) and is connected, pipeline (40) extend to in detecting tube (20) and the end is located test paper (30) below, install the switch module who is used for putting through or breaking through sample pipe (10) and detecting tube (20) on pipeline (40) that are located through-hole A and through-hole B (21).
2. The integrated device for collecting and detecting the sample of the respiratory system infection viroid according to claim 1, wherein: the pipeline (40) is a hose, the switch assembly is an air bag (50) coated on the pipeline (40) positioned in the through hole A and the through hole B (21), the air bag (50) is filled with gas with large pressure, and the through hole A is communicated with the through hole B (21) by deflating the air bag (50).
3. The integrated device for collecting and detecting the sample of the respiratory system infection viroid according to claim 2, wherein: a supporting plate (51) is arranged between the sample tube (10) and the detection tube (20), and a bevel gear part (52) is arranged on one side, close to the air bag (50), of the supporting plate (51).
4. The integrated device for collecting and detecting the sample of the respiratory system infection viroid according to claim 1, wherein: the pipeline (40) is a hard pipe and is provided with two sections, one section is connected with the through hole A, and the other section is connected with the through hole B (21); the switch assembly comprises a circular sliding groove formed in the top of the detection tube (20) and a rotary cylinder (60) with openings at two ends capable of sleeving the sample tube (10) and the detection tube (20), the bottom of a pipeline (40) connected with the through hole A is located in the circular sliding groove (61), the through hole B (21) is located at the bottom of the circular sliding groove, and the bottom of the pipeline (40) connected with the through hole A is communicated with the through hole B (21) by rotating the sample tube (10).
5. The integrated device for collecting and detecting the sample of the respiratory system infection viroid according to claim 4, wherein: and a sealing ring is arranged in the circular sliding groove (61).
6. The integrated device for collecting and detecting the sample of the respiratory system infection viroid according to claim 1, wherein: the detection test paper is sequentially a sample pad (31), a colloidal gold pad (32), a nitrocellulose membrane (33) and a water absorption pad (34) from bottom to top, and a detection line (35) and a quality control line (36) are arranged on the nitrocellulose membrane (33).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020618429.8U CN212533003U (en) | 2020-04-22 | 2020-04-22 | Respiratory system infects integrative device of viroid sample collection detection |
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| CN202020618429.8U CN212533003U (en) | 2020-04-22 | 2020-04-22 | Respiratory system infects integrative device of viroid sample collection detection |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114113653A (en) * | 2021-12-10 | 2022-03-01 | 盐城凯龙药业有限公司 | Anti-pollution nucleic acid detecting tube for preventing liquid leakage and application thereof |
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2020
- 2020-04-22 CN CN202020618429.8U patent/CN212533003U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114113653A (en) * | 2021-12-10 | 2022-03-01 | 盐城凯龙药业有限公司 | Anti-pollution nucleic acid detecting tube for preventing liquid leakage and application thereof |
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