CN110419764A - Chewing gum, electronic cigarette liquid and application thereof - Google Patents
Chewing gum, electronic cigarette liquid and application thereof Download PDFInfo
- Publication number
- CN110419764A CN110419764A CN201910683324.2A CN201910683324A CN110419764A CN 110419764 A CN110419764 A CN 110419764A CN 201910683324 A CN201910683324 A CN 201910683324A CN 110419764 A CN110419764 A CN 110419764A
- Authority
- CN
- China
- Prior art keywords
- parts
- chewing gum
- ethyl
- electronic cigarette
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000015218 chewing gum Nutrition 0.000 title claims abstract description 78
- 229940112822 chewing gum Drugs 0.000 title claims abstract description 74
- 239000003571 electronic cigarette Substances 0.000 title claims abstract description 44
- 239000007788 liquid Substances 0.000 title claims abstract description 39
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 54
- 210000000214 mouth Anatomy 0.000 claims abstract description 20
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 15
- 239000003765 sweetening agent Substances 0.000 claims abstract description 15
- 238000004140 cleaning Methods 0.000 claims abstract description 14
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 11
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000000126 substance Substances 0.000 claims abstract description 11
- 239000000811 xylitol Substances 0.000 claims abstract description 11
- 235000010447 xylitol Nutrition 0.000 claims abstract description 11
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 11
- 229960002675 xylitol Drugs 0.000 claims abstract description 11
- 230000000675 anti-caries Effects 0.000 claims abstract description 10
- 239000002826 coolant Substances 0.000 claims abstract description 9
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims abstract description 6
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims abstract description 6
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims abstract description 6
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims abstract description 6
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims abstract description 6
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims abstract description 6
- 239000008101 lactose Substances 0.000 claims abstract description 6
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims abstract description 5
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims abstract description 5
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 claims abstract description 5
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 claims abstract description 5
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 claims abstract description 5
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims abstract description 5
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims abstract description 5
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229940013618 stevioside Drugs 0.000 claims abstract description 5
- 235000019202 steviosides Nutrition 0.000 claims abstract description 5
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims abstract description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 41
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 claims description 20
- 239000000203 mixture Substances 0.000 claims description 19
- 239000000284 extract Substances 0.000 claims description 18
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 claims description 17
- 244000131522 Citrus pyriformis Species 0.000 claims description 16
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 claims description 16
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
- 235000005979 Citrus limon Nutrition 0.000 claims description 15
- 239000003814 drug Substances 0.000 claims description 15
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 claims description 15
- 244000269722 Thea sinensis Species 0.000 claims description 13
- XPCTZQVDEJYUGT-UHFFFAOYSA-N 3-hydroxy-2-methyl-4-pyrone Chemical compound CC=1OC=CC(=O)C=1O XPCTZQVDEJYUGT-UHFFFAOYSA-N 0.000 claims description 12
- PPXUHEORWJQRHJ-UHFFFAOYSA-N ethyl isovalerate Chemical compound CCOC(=O)CC(C)C PPXUHEORWJQRHJ-UHFFFAOYSA-N 0.000 claims description 12
- 239000000796 flavoring agent Substances 0.000 claims description 12
- 235000019634 flavors Nutrition 0.000 claims description 12
- 229940094952 green tea extract Drugs 0.000 claims description 12
- 235000020688 green tea extract Nutrition 0.000 claims description 12
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 claims description 11
- 241000218378 Magnolia Species 0.000 claims description 11
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical class CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims description 10
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims description 10
- 229940087305 limonene Drugs 0.000 claims description 10
- 235000001510 limonene Nutrition 0.000 claims description 10
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 claims description 10
- -1 ethoxycarbonylmethyl Chemical group 0.000 claims description 9
- LCZUOKDVTBMCMX-UHFFFAOYSA-N 2,5-Dimethylpyrazine Chemical compound CC1=CN=C(C)C=N1 LCZUOKDVTBMCMX-UHFFFAOYSA-N 0.000 claims description 8
- OCWLYWIFNDCWRZ-UHFFFAOYSA-N Methyl (S)-2-Methylbutanoate Chemical compound CCC(C)C(=O)OC OCWLYWIFNDCWRZ-UHFFFAOYSA-N 0.000 claims description 8
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 claims description 8
- UAHWPYUMFXYFJY-UHFFFAOYSA-N beta-myrcene Chemical compound CC(C)=CCCC(=C)C=C UAHWPYUMFXYFJY-UHFFFAOYSA-N 0.000 claims description 8
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims description 8
- 150000002148 esters Chemical class 0.000 claims description 8
- FKRCODPIKNYEAC-UHFFFAOYSA-N ethyl propionate Chemical compound CCOC(=O)CC FKRCODPIKNYEAC-UHFFFAOYSA-N 0.000 claims description 8
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims description 8
- IFYYFLINQYPWGJ-UHFFFAOYSA-N gamma-decalactone Chemical compound CCCCCCC1CCC(=O)O1 IFYYFLINQYPWGJ-UHFFFAOYSA-N 0.000 claims description 8
- ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 claims description 8
- AOGQPLXWSUTHQB-UHFFFAOYSA-N hexyl acetate Chemical compound CCCCCCOC(C)=O AOGQPLXWSUTHQB-UHFFFAOYSA-N 0.000 claims description 8
- MLFHJEHSLIIPHL-UHFFFAOYSA-N isoamyl acetate Chemical compound CC(C)CCOC(C)=O MLFHJEHSLIIPHL-UHFFFAOYSA-N 0.000 claims description 8
- DPNGWXJMIILTBS-UHFFFAOYSA-N myosmine Chemical compound C1CCN=C1C1=CC=CN=C1 DPNGWXJMIILTBS-UHFFFAOYSA-N 0.000 claims description 8
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 8
- 235000013824 polyphenols Nutrition 0.000 claims description 8
- 235000013616 tea Nutrition 0.000 claims description 8
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims description 8
- YKFLAYDHMOASIY-UHFFFAOYSA-N γ-terpinene Chemical compound CC(C)C1=CCC(C)=CC1 YKFLAYDHMOASIY-UHFFFAOYSA-N 0.000 claims description 8
- 229940043350 citral Drugs 0.000 claims description 7
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 6
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 6
- YIKYNHJUKRTCJL-UHFFFAOYSA-N Ethyl maltol Chemical compound CCC=1OC=CC(=O)C=1O YIKYNHJUKRTCJL-UHFFFAOYSA-N 0.000 claims description 6
- HYMLWHLQFGRFIY-UHFFFAOYSA-N Maltol Natural products CC1OC=CC(=O)C1=O HYMLWHLQFGRFIY-UHFFFAOYSA-N 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 6
- 229940093503 ethyl maltol Drugs 0.000 claims description 6
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- 229940041616 menthol Drugs 0.000 claims description 6
- DTUQWGWMVIHBKE-UHFFFAOYSA-N phenylacetaldehyde Chemical compound O=CCC1=CC=CC=C1 DTUQWGWMVIHBKE-UHFFFAOYSA-N 0.000 claims description 6
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- FQTLCLSUCSAZDY-UHFFFAOYSA-N (+) E(S) nerolidol Natural products CC(C)=CCCC(C)=CCCC(C)(O)C=C FQTLCLSUCSAZDY-UHFFFAOYSA-N 0.000 claims description 4
- NPFVOOAXDOBMCE-PLNGDYQASA-N (3Z)-hex-3-en-1-yl acetate Chemical compound CC\C=C/CCOC(C)=O NPFVOOAXDOBMCE-PLNGDYQASA-N 0.000 claims description 4
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- 239000001934 2,5-dimethylpyrazine Substances 0.000 claims description 4
- AYJXHIDNNLJQDT-UHFFFAOYSA-N 2,6,6-Trimethyl-2-cyclohexene-1,4-dione Chemical compound CC1=CC(=O)CC(C)(C)C1=O AYJXHIDNNLJQDT-UHFFFAOYSA-N 0.000 claims description 4
- 239000001278 2-(5-ethenyl-5-methyloxolan-2-yl)propan-2-ol Substances 0.000 claims description 4
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- WGPCZPLRVAWXPW-NSHDSACASA-N 5-octyloxolan-2-one Chemical compound CCCCCCCC[C@H]1CCC(=O)O1 WGPCZPLRVAWXPW-NSHDSACASA-N 0.000 claims description 4
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- 150000001299 aldehydes Chemical class 0.000 claims description 3
- NFLGAXVYCFJBMK-IUCAKERBSA-N (-)-isomenthone Chemical compound CC(C)[C@@H]1CC[C@H](C)CC1=O NFLGAXVYCFJBMK-IUCAKERBSA-N 0.000 claims description 2
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- 150000001335 aliphatic alkanes Chemical class 0.000 claims description 2
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- NFLGAXVYCFJBMK-UHFFFAOYSA-N isomenthone Natural products CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 claims description 2
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- UJNOLBSYLSYIBM-WISYIIOYSA-N [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] (2r)-2-hydroxypropanoate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)[C@@H](C)O UJNOLBSYLSYIBM-WISYIIOYSA-N 0.000 claims 1
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- XHXUANMFYXWVNG-ADEWGFFLSA-N (-)-Menthyl acetate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(C)=O XHXUANMFYXWVNG-ADEWGFFLSA-N 0.000 description 2
- 244000144730 Amygdalus persica Species 0.000 description 2
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- 229940090910 ethyl 2-methylbutyrate Drugs 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
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- 238000001256 steam distillation Methods 0.000 description 2
- 235000019605 sweet taste sensations Nutrition 0.000 description 2
- 239000012085 test solution Substances 0.000 description 2
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
- 239000001605 (5-methyl-2-propan-2-ylcyclohexyl) acetate Substances 0.000 description 1
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 1
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- 235000007421 Mentha citrata Nutrition 0.000 description 1
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- 240000003637 Monarda citriodora Species 0.000 description 1
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- 241000194019 Streptococcus mutans Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 235000010358 acesulfame potassium Nutrition 0.000 description 1
- 229960004998 acesulfame potassium Drugs 0.000 description 1
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- 230000004913 activation Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000008122 artificial sweetener Substances 0.000 description 1
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- 239000000605 aspartame Substances 0.000 description 1
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 description 1
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- 230000015572 biosynthetic process Effects 0.000 description 1
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- 235000019504 cigarettes Nutrition 0.000 description 1
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- 230000001408 fungistatic effect Effects 0.000 description 1
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- 235000012907 honey Nutrition 0.000 description 1
- FVYXIJYOAGAUQK-UHFFFAOYSA-N honokiol Chemical compound C1=C(CC=C)C(O)=CC=C1C1=CC(CC=C)=CC=C1O FVYXIJYOAGAUQK-UHFFFAOYSA-N 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000015689 metaplastic ossification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920001206 natural gum Polymers 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229940085605 saccharin sodium Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
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- 230000000638 stimulation Effects 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 238000002137 ultrasound extraction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/068—Chewing gum characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/12—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Confectionery (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
This application involves a kind of chewing gums, electronic cigarette liquid and application thereof.The chewing gum of the application includes the substance of following parts by weight: 10 to 50 parts of sweetener, 5 to 20 parts of coolant agent and 15 to 85 parts of propylene glycol；Wherein the sweetener includes at least one of xylitol, maltose, stevioside, rhamnose, trehalose, antierythrite, lactose and galactolipin.The chewing gum can be atomized entrance by the various atomizers such as electronic cigarette, ultrasonic atomizer, net formula atomizer.The chewing gum is applied to that electronic cigarette is made to have cleaning oral cavity, the effect of pre- anti-caries in electronic cigarette.
Description
Technical field
This application involves the field more particularly to a kind of chewing gum of electronics aerosol or electronic atomization device and its it is being atomized
Application in device.
Background technique
Traditional chewing gum is that syrup, peppermint, sweetener etc. is added using natural gum or glycerol resin as the basis of colloid
A kind of sugar being put into chewing in mouth for user made of reconciliation compacting.It is fragrant that board-like chewing gum, bubble gum and sugar-coat mouth can be divided into
Three kinds of sugar.Chewing gum can clean oral cavity, promote oral health, but its residue main ingredient is matrix, matrix belongs to macromolecule
Substance, it is difficult to degrade, it is not absorbed by the body, is sticked on the ground, be difficult to be cleaned on carpet, and be easy to be sticky with dust and bacterium, it is dirty
Contaminate environment；If swallowed accidentally by children, it is easy to happen danger；And chewing can have a negative impact to face for a long time.
Therefore it provides a kind of chewing gum that can be solved the above problems and its application method in atomising device.
Summary of the invention
For the application by providing a kind of chewing gum and its application method without containing colloid, it is fragrant which is free of traditional mouth
Matrix in sugar, ingredient are degradable, edible, the matrix residues in no conventional chewing gum, without difficult cleaning and dirt
The problem of contaminating environment will not have a negative impact to face without chewing.The chewing gum can be generated by atomising device for making
The aerosol of user's sucking, and play the role of cleaning oral cavity, pre- anti-caries.
According to the application level, this application provides a kind of chewing gums, and it includes the substances of following parts by weight: 10
To 50 parts of sweeteners, 5 to 20 parts of coolant agent and 15 to 85 parts of propylene glycol；Wherein the sweetener includes xylitol, wheat
At least one of bud sugar, stevioside, rhamnose, trehalose, antierythrite, lactose and galactolipin.
According to another level of the application, this application provides a kind of electronic cigarette liquids, and it includes above-mentioned chewing gums.
According to another level of the application, this application provides a kind of atomising devices, and it includes above-mentioned chewing gum or electronics
Tobacco juice.
According to another level of the application, this application provides the users of a kind of above-mentioned chewing gum or electronic cigarette liquid
Method, wherein the chewing gum or electronic cigarette liquid can be atomized the aerosol for generating and sucking for user by atomising device.The application's
Chewing gum or electronic cigarette liquid can play the role of cleaning oral cavity or pre- anti-caries.
The additional level and advantage of the embodiment of the present application will be described partly in subsequent instruction, be shown or via this
Apply for the implementation of embodiment and illustrates.
Specific embodiment
Embodiments herein will be shown hereinafter by detailed retouch.Embodiments herein does not answer described be interpreted
Limitation to the application.
In addition, sometimes herein with range format presentation amount, ratio and other numerical value.It should be understood that such range format
It is that and should neatly understand for convenient and for purpose of brevity, not only comprising being expressly specified as the numerical value of scope limitation, but also wraps
Containing all individual numbers or the subrange being covered by the range, as explicitly specifying each numerical value and subrange.
As used herein, term " substantially ", " substantially ", " generally ", " essence " and " about " is to describe and illustrate
Small variation.When being used in combination with event or situation, the term can be referred to the example that wherein event or situation accurately occur
And the example that wherein event or situation pole approximatively occur.For example, when combination numerical value is in use, term can be referred to be less than
Or ± 10% variation range equal to the numerical value, e.g., less than or equal to ± 5%, be less than or equal to ± 4%, be less than or wait
In ± 3%, be less than or equal to ± 2%, be less than or equal to ± 1%, being less than or equal to ± 0.5%, being less than or equal to ± 0.1%,
Or it is less than or equal to ± 0.05%.For example, if the difference between two values is less than or equal to the average value of described value
± 10% (e.g., less than or equal to ± 5%, be less than or equal to ± 4%, be less than or equal to ± 3%, be less than or equal to ± 2%,
Less than or equal to ± 1%, it is less than or equal to ± 0.5%, is less than or equal to ± 0.1% or is less than or equal to ± 0.05%), that
It is believed that described two numerical value " generally " are identical.
In specific embodiment and claims, by term at least one of at least one of " ", " ", " in
At least one " or the list of project that is connected of other term similars may imply that any combination of listed item.For example, such as
Fruit lists project A and B, then phrase " at least one of A and B " means only A；Only B；Or A and B.In another example, such as
Fruit lists project A, B and C, then phrase " at least one of A, B and C " means only A；Or only B；Only C；A and B (excluding C)；
A and C (excluding B)；B and C (excluding A)；Or the whole of A, B and C.Project A may include discrete component or multiple element.Project B can
Include discrete component or multiple element.Project C may include discrete component or multiple element.
Herein, term " aerosol for user's sucking " may include but being not limited to, aerosol, suspension liquid,
Low-temperature steam and escaping gas.
The application provides a kind of chewing gum and its application method, sucks atomization for the simpler more environmentally friendly method of user
Chewing gum afterwards plays the role of cleaning oral cavity.Meanwhile the application provides a kind of application of chewing gum in electronic cigarette, uses
Person can play the role of cleaning oral cavity, pre- anti-caries while sucking electronic cigarette.
According to the application level, this application provides a kind of chewing gum, the chewing gum includes following parts by weight
Substance: about 10 to about 50 parts of sweetener, about 5 to about 20 parts of coolant agent and about 15 to about 85 parts of propylene glycol.
In some embodiments, parts by weight of the sweetener in chewing gum substantially, for example, 10 parts, 15 parts, 20 parts, 25
The range of both any composition in part, 30 parts, 35 parts, 40 parts, 45 parts, 50 parts or these numbers.In some embodiments, cool taste
Parts by weight of the agent in chewing gum substantially, for example, both any composition in 5 parts, 10 parts, 15 parts, 20 parts or these numbers
Range.In some embodiments, parts by weight of the propylene glycol in chewing gum substantially, for example, 15 parts, 20 parts, 25 parts, 30 parts,
Both any group in 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts, 65 parts, 70 parts, 75 parts, 80 parts, 85 parts or these numbers
At range.
Sweetener is additive, the impression that can make product that user be allowed to generate sweet taste when in use.Sweetener is by system
Preparation Method can be divided into artificial synthesis edulcorant and natural sweetener.The example of artificial sweetener include, but are not limited to, saccharin sodium,
Honey element, Aspartame, acesulfame potassium.The example of natural sweetener include, but are not limited to, xylitol, maltose, stevioside, mouse
Lee's sugar, trehalose, antierythrite, lactose.
In some embodiments, the sweetener is natural sweetener comprising selected from by xylitol, maltose, stevia rebaudianum
Group composed by sugar, rhamnose, trehalose, antierythrite, lactose and galactolipin and combinations thereof.In further embodiments,
The sweetener is xylitol.The xylitol that the application chewing gum is added by it can reach the effect in cleaning oral cavity.
Coolant agent is additive, for impression and the stimulation that can make product that user be allowed to generate cooling effect when in use
The not strong chemicals of property.In some embodiments, the coolant agent includes selected from by menthol, menthones, isomenthone, lactic acid
Menthyl ester, WS-23 (N, 2,3- trimethyl -2- butanamide), WS-3 (N- ethyl-is to menthyl -3- formamide), WS-5
(N- (ethoxycarbonylmethyl group)-is to alkane -3- formamide), WS-12 (N- (4- methoxyphenyl)-is to menthyl -3- carboxylic acid amides), second
Group composed by sour menthyl ester and combinations thereof.
In some embodiments, the chewing gum also includes the substance of following parts by weight: about 0 to about 15 part of Chinese traditional medicine composition
Object.In some embodiments, parts by weight of the Chinese medicine composition in chewing gum are approximately about, for example, 1 part, 2 parts, 3 parts, 4 parts, 5
The range of both any composition in part, 10 parts, 15 parts or these numbers.
The Chinese medicine composition includes one of lemon extract, Magnolia cortex P.E, green-tea extract or a variety of, wherein
The lemon extract includes at least one of limonene, citral and linalool, and the Magnolia cortex P.E includes magnolol
And at least one of honokiol, and the green-tea extract includes at least one of tea polyphenols and caffeine.Some
In embodiment, the Chinese medicine composition includes magnolol.
Lemon extract has the function of antibacterial, removing free radical.Magnolia cortex P.E is antibacterial, remove free radical, dissolving phlegm stops
The effects of cough.Green-tea extract has the effects that anti-oxidant.The Chinese medicine composition that the application chewing gum is added by it, can reach
The effect for the effects of cleaning oral cavity, pre- anti-caries.
In some embodiments, the lemon extract is to be obtained using extraction by steam distillation.Specifically, the water
Steam distillation method, which comprises the steps of:, is separately added into lemon or peppermint raw material in cucurbit, and about 8 to about 15 times of quality are added
Pure water, heating distillation are extracted about 3 hours to about 6 hours, collect distillate to obtain lemon extract.In some embodiments,
Lemon can be fresh, be also possible to dry (such as drying in the shade).
In some embodiments, the Magnolia cortex P.E and the green-tea extract are to be obtained using organic solvent extraction
, the organic solvent of the extraction is that the volume fraction of ethyl alcohol is about 40% to about 80%.Specifically, the organic solvent mentions
It follows the example of and comprises the steps of:
(1) by Cortex Magnoliae Officinalis or green tea materials crushed after being dried, the ethyl alcohol that about 8 to about 15 times of quality are added extracts about at normal temperature
16 hours to about 72 hours, wherein the volume fraction of ethyl alcohol was about 40% to about 80%.Extracting solution is filtered, it, will be residual after filtering
The ethanol solution that slag adds about 8 to about 15 times of quality extracts about 12 hours to about 48 hours at normal temperature, filtering.
(2) subsequent merging filtrate, after filtrate decompression is concentrated, with macroporous resin adsorption.It the use of volume fraction is about 70%
Ethyl alcohol to about 90% repeatedly elutes the macroreticular resin after absorption, eluent is collected, after eluent is concentrated under reduced pressure, then through cold
It is lyophilized dry, Cortex Magnoliae Officinalis or green-tea extract can be obtained.
In some embodiments, in step (1), Magnolia cortex P.E is the second of about 40% to about 60% using volume fraction
Alcohol extracting, green-tea extract are extracted using the ethyl alcohol that volume fraction is about 70% to about 80%.
In some embodiments, in step (2), when eluting to macroreticular resin, Magnolia cortex P.E uses volume fraction about
The ethanol elution of 80% to about 90%；Green-tea extract uses the ethanol elution of volume fraction about 70% to about 80%.
In some embodiments, macroreticular resin is D-101 type non-polar resin.
In some embodiments, the process conditions being freeze-dried in the step (2) are as follows: precooling temperature be about -20 DEG C extremely
About -50 DEG C, the precooling time is about 15 hours to about 30 hours, freeze-drying temperature in about -40 DEG C to about 20 DEG C temperature programmings,
Sublimation drying is about 24 hours to about 72 hours, and is freeze-dried at about 4Pa to the pressure of about 107Pa.
According to another level of the application, the chewing gum also includes the substance of following parts by weight: about 0 to about 15 part
Flavor components, wherein the flavor components include in limonene, citral, linalool, magnolol, tea polyphenols and caffeine extremely
Few one kind.The flavor components that the application chewing gum is added by it can promote fungistatic effect and reach cleaning oral cavity when in use
Effect.
In some embodiments, above-mentioned chewing gum can further include the essence of about 0.01 to about 25 parts by weight.One
In a little embodiments, parts by weight content of the essence in chewing gum be, for example, 0.01 part, 0.05 part, 0.1 part, 0.25 part,
The range of both any composition in 0.5 part, 1 part, 5 parts, 10 parts, 15 parts, 20 parts, 25 parts or these numbers.
Essence is any essence that can be used in electronic cigarette liquid in this field, such as, but not limited to, watermelon flavor, green tea
Taste essence.In some embodiments, the essence includes selected from by australene, benzyl alcohol, benzaldehyde, phenylacetaldehyde, benzoic acid
Benzyl ester, neral, nerol, geraniol, indoles, jasmone, nerolidol, strawberry aldehyde, dihydrojasmonate, dihydro Mi
It is monkey peach lactones, eugenol, beta-myrcene, cymene, diethyl sebacate, methyl 2-methylbutyrate, ethyl 2-methylbutyrate, different
Ethyl valerate, γ-terpinene, γ-terpinol, γ-hexalactone, γ-octalactone, γ-decalactone, the pungent butyl ester of γ-, γ-ten one
Lactone, γ-dodecalactone, leaf-alcohol, hexanol, amylalcohol, 2,5- dimethyl pyrazine, acid methylester, ethyl cinnamate, ethylmaltol,
Ethyl isovalerate, melonal, vanillic aldehyde, methyl heptenone, maltol, ethylmaltol, acetic acid 2- methylbutyl butenoate, acetic acid second
Ester, butyl acetate, isoamyl acetate, hexyl acetate, Leaf Acetate, propionic acid, ethyl propionate, ethyl butyrate, 2-Methyl Butyric Acid
Ethyl ester, myosmine, triacetyl glycerine, linalool oxide, benzyl carbinol, ketoisophorone, cis- 6- nonenol and combinations thereof
Composed group.
It will be understood by those skilled in the art that the chewing gum of the embodiment of the present application can be any according to practical preparation demand selection
Suitable known method manufacture, and be not limited except as.
According to another level of the application, this application provides a kind of electronic cigarette liquid, the electronic cigarette liquid includes above-mentioned
Chewing gum in embodiment.
In some embodiments, the electronic cigarette liquid includes the substance of following parts by weight: about 0.5 to about 20 part of sweet taste
Agent, about 0.25 to about 8 part of coolant agent, about 0 to about 6 part of flavor components or Chinese medicine composition, about 0 to about 5 part of nicotine
Salt, about 30 to about 60 parts of glycerol and about 10 to about 65 parts of propylene glycol；Wherein the flavor components include limonene, lemon
At least one of aldehyde, linalool, magnolol, tea polyphenols and caffeine, the Chinese medicine composition include lemon extract, Cortex Magnoliae Officinalis
At least one of extract and green-tea extract.In some embodiments, weight of the nicotine salt in electronic cigarette liquid
Part content is, for example, 0 part, 0.5 part, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 4 parts, 5 parts.
It should be understood that those skilled in the art can select any of nicotine salt in this field to be added according to actual needs
In electronic cigarette liquid, and it is not limited except as.In some embodiments, the nicotine salt includes benzoate.
In some embodiments, the electronic cigarette liquid can further include the essence of about 0.01 to about 10 parts by weight.In
In some embodiments, parts by weight content of the essence in chewing gum is, for example, 0.01 part, 0.05 part, 0.1 part, 0.25
The range of both any composition in part, 0.5 part, 1 part, 5 parts, 10 parts or these numbers.
Essence is any essence that can be used in electronic cigarette liquid in this field, such as, but not limited to, watermelon flavor, green tea
Taste essence.In some embodiments, the essence includes selected from by australene, benzyl alcohol, benzaldehyde, phenylacetaldehyde, benzoic acid
Benzyl ester, neral, nerol, geraniol, indoles, jasmone, nerolidol, strawberry aldehyde, dihydrojasmonate, dihydro Mi
It is monkey peach lactones, eugenol, beta-myrcene, cymene, diethyl sebacate, methyl 2-methylbutyrate, ethyl 2-methylbutyrate, different
Ethyl valerate, γ-terpinene, γ-terpinol, γ-hexalactone, γ-octalactone, γ-decalactone, the pungent butyl ester of γ-, γ-ten one
Lactone, γ-dodecalactone, leaf-alcohol, hexanol, amylalcohol, 2,5- dimethyl pyrazine, acid methylester, ethyl cinnamate, ethylmaltol,
Ethyl isovalerate, melonal, vanillic aldehyde, methyl heptenone, maltol, ethylmaltol, acetic acid 2- methylbutyl butenoate, acetic acid second
Ester, butyl acetate, isoamyl acetate, hexyl acetate, Leaf Acetate, propionic acid, ethyl propionate, ethyl butyrate, 2-Methyl Butyric Acid
Ethyl ester, myosmine, triacetyl glycerine, linalool oxide, benzyl carbinol, ketoisophorone, cis- 6- nonenol and combinations thereof
Composed group.
According to some embodiments of the application, the application provides the preparation method of electronic cigarette liquid, and it includes following steps: by Buddhist nun
Ancient fourth salt and chewing gum prepare respectively, then by embodiment provide range in special ratios mixing, then be added essence,
Then nicotine salt is added propylene glycol and glycerol, mixes it uniformly to obtain electronic cigarette liquid.
According to another level of the application, this application provides a kind of atomising devices, wherein the atomising device includes
Chewing gum or electronic cigarette liquid in above-described embodiment.The chewing gum or the electronic cigarette liquid can be atomized by the atomising device
Generate the aerosol sucked for user.
In some embodiments, the atomising device includes electronic cigarette, ultrasonic atomizer or net formula atomizer.
Electronic cigarette liquid provided by the embodiments of the present application, due to that can be inhaled meeting containing the chewing gum in above-described embodiment
Play the role of cleaning oral cavity, pre- anti-caries while cigarette person is to smoking addiction demand.
Embodiment
To facilitate a better understanding of the application, it is illustrated by the following examples.These examples belong to the protection of the application
Range, but the protection scope of the application is not limited.
The preparation of lemon extract
The peppermint raw material of dry lemon raw material and drying is separately added into cucurbit, the pure water of 12 times of quality is added,
Heating distillation is extracted 5 hours, is collected distillate and is obtained lemon extract.
The preparation of Magnolia cortex P.E or green-tea extract
By magnolia bark raw material crushed after being dried, the ethyl alcohol that 8 times of quality are added extracts 24 hours at normal temperature, wherein the body of ethyl alcohol
Fraction is 50%.Extracting solution is filtered, after filtering, the ethanol solution that residue adds 8 times is extracted 24 hours at normal temperature,
Filtering.Subsequent merging filtrate, after filtrate decompression is concentrated, with macroporous resin adsorption.The ethyl alcohol pair for the use of volume fraction being 85%
Macroreticular resin after absorption elutes 3 times, collects eluent, after eluent is concentrated under reduced pressure, then it is freeze-dried, Cortex Magnoliae Officinalis can be obtained
Extract.
By green tea materials crushed after being dried, the ethyl alcohol that 15 times of quality are added extracts 48 hours at normal temperature, wherein ethyl alcohol
Volume fraction is 70%.Extracting solution is filtered, after filtering, it is small that the ethanol solution that residue adds 15 times is extracted 24 at normal temperature
When, filtering.Subsequent merging filtrate, after filtrate decompression is concentrated, with macroporous resin adsorption.The ethyl alcohol for the use of volume fraction being 75%
Macroreticular resin after absorption is eluted 4 times, eluent is collected, after eluent is concentrated under reduced pressure, then it is freeze-dried, it can obtain green
Tea extraction.
Chewing gum:
Embodiment 1
By 30g xylitol, 13g menthol and 54g mixed with propylene glycol, stirs evenly, obtain chewing gum.
Embodiment 2
By 30g xylitol, 13g menthol, 2g limonene, 1g citral and 54g mixed with propylene glycol, stirs evenly, obtain
Chewing gum.
Embodiment 3
The difference from example 2 is that replacing 2g limonene and 1g citral with 3g lemon extract.
Embodiment 4
By 20g xylitol, 10g antierythrite, 4g menthol, 5gWS-23,2g magnolol and 59g mixed with propylene glycol, stirring
Uniformly, chewing gum is obtained.
Embodiment 5
Difference with embodiment 4 is to replace 2g magnolol with 2g Magnolia cortex P.E.
Embodiment 6
By 5g xylitol, 10g maltose, 5g trehalose, 5g lactose, 5g menthol, 10g WS-3,3g limonene, 2g lemon
Lemon aldehyde, 3g tea polyphenols and 52g mixed with propylene glycol, stir evenly, obtain chewing gum.
Embodiment 7
Difference with embodiment 6 is with 5g lemon extract replacement 3g limonene and 2g citral and 3g green-tea extract
Replace 3g tea polyphenols.
Embodiment 8
By 10g stevioside, 8g rhamnose, 8g galactolipin, 3.5gWS-3,5g menthyl acetate, 2g limonene, 3g Cortex Magnoliae Officinalis
Phenol, 5g tea polyphenols and 51g mixed with propylene glycol, stir evenly, obtain chewing gum.
Electronic cigarette liquid comprising chewing gum:
Embodiment 9
The 20g chewing gum that embodiment 2 provides is mixed with 3g nicotine salt, then be added 24g propylene glycol, 50g glycerol and
3g essence I is uniformly mixed, and electronic cigarette liquid is obtained after stirring.
Embodiment 10
Difference with embodiment 9 is that the 20g mouth provided with the 20g chewing gum alternative embodiment 2 that embodiment 3 provides is fragrant
Sugar.
Embodiment 11
The 25g chewing gum that embodiment 4 provides is mixed with 2g nicotine salt, then be added 25g propylene glycol, 45g glycerol and
3g essence II is uniformly mixed, and electronic cigarette liquid is obtained after stirring.
Embodiment 12
Difference with embodiment 11 is that the 25g mouth provided with the 25g chewing gum alternative embodiment 4 that embodiment 5 provides is fragrant
Sugar.
Embodiment 13
The 15g chewing gum that embodiment 6 provides is mixed with 5g nicotine salt, then be added 20g propylene glycol, 55g glycerol and
5g essence III is uniformly mixed, and electronic cigarette liquid is obtained after stirring.
Embodiment 14
Difference with embodiment 13 is that the 15g mouth provided with the 15g chewing gum alternative embodiment 6 that embodiment 7 provides is fragrant
Sugar.
Embodiment 15
The 30g chewing gum that embodiment 8 provides is mixed with 4g benzoic acid nicotine salt, 21g propylene glycol, 40g is then added
Glycerol and 5g essence IV are uniformly mixed, and electronic cigarette liquid is obtained after stirring.
Embodiment 16
The chewing gum that 1g embodiment 4 provides is mixed with 2g nicotine salt, 47g propylene glycol then is added and 50g glycerol is equal
Even mixing obtains electronic cigarette liquid after stirring.
The composition of each essence is as shown in table 1 below in above-described embodiment 9 to 15.
Table 1
After the completion of the chewing gum of above-described embodiment 1-8 and the electronic cigarette liquid of embodiment 9-16, Bacteria suppression survey is then carried out
Examination.
Bacteria suppression test mode；
Sample preparation: CORESTA (Cooperation Centre for Scientific Research is used
Relative to Tobacco) standard (test document: ISO 20768:2018) by atomising device (electronic cigarette) by sample mist
Metaplasia collects aerosol at aerosol, and using cambridge filter, and absorption aerosol weight is 0.716g.Then cambridge filter is put into small
In beaker, 50% ethyl alcohol of 7.16mL is then added, using ultrasonic extraction 30mins, it is molten to be made into the extraction that concentration is 100mg/mL
Liquid.Extraction solution is diluted to obtain into graded series concentration (50,25,12.5,6.25,3.125,1.562,0.781mg/mL)
Test solution.
The preparation of bacteria suspension: the strain of preservation: Streptococcus mutans (ATCC 25175) and tooth is taken out from -80 DEG C of environment
Gum Detection of Porphyromonas (ATCC 33277), therefrom the appropriate bacterium colony of picking is placed on plate, and 36h activation is cultivated at 37 DEG C.With
After pick from the plate appropriate bacterium colony and be placed in another plate, 36h is cultivated at 37 DEG C, and repeat the step 2 time.
With oese picking proper amount of strains in centrifuge tube, shake well is diluted to obtain 105To 106The bacterium of CFU/mL is outstanding
Liquid.
Preparation with medicine plate: taking the test solution 1mL of various concentration, is added in culture dish, then be added in culture dish
The culture medium of 9mL, shakes up.Be configured to graded series concentration (10,5,2.5,1.25,0.625,0.3125,0.1562,
Drug plates 0.0781mg/mL), sample solvent are negative control, and culture dish is horizontally arranged after being finished down, solidifies culture medium,
It is spare.
Bacteria suppression measurement: 100 μ L bacteria suspensions are taken to be added in uniformly spreadable on band medicine plate.Culture is inverted for 24 hours in 37 DEG C,
Observation is for trying bacterium growing state, and the minimum sample concentration for recording complete inhibition bacterial growth is to inhibit dense to the minimum for trying bacterium
It spends (Minimum Inhibitory Concentration, MIC).
The chewing gum of embodiment 1-8 and the electronic cigarette liquid of embodiment 9-16 pass through Bacteria suppression test, and test result is as follows
Shown in table 2.
Table 2
By data in table 1 it is found that the electronic cigarette liquid of the chewing gum of the embodiment of the present application 1-8 and embodiment 9-16 through atomization,
Still it can inhibit the growth of bacterium after dilution, effectively to reach the effects of cleaning oral cavity, pre- anti-caries.Compared to embodiment
16, the chewing gum in the electronic cigarette liquid of embodiment 9-15 forms the antibacterial effect in concentration range provided by the embodiments of the present application
Fruit is more obvious.
In addition, by comparing embodiment 1 and the antibacterial test result of the chewing gum of embodiment 2-8 it is found that being added to flavor
The embodiment of composition or Chinese medicine composition, antibacterial effect, which has, to be more obviously improved.For example, in embodiment 8, chewing gum
Bacterium can more effectively be inhibited comprising Magnolia cortex P.E and make its MIC down to 0.1562mg/mL.
It is described by the above embodiments of the present application it should be appreciated that this application provides a kind of chewing gum and its application method
Chewing gum can generate the aerosol sucked for user by atomising device can play cleaning in chewing gum aerosol suction inlet
The effects of oral cavity, pre- anti-caries.In addition, the application provides a kind of electronic cigarette liquid comprising the chewing gum, pass through atomizer mist
It is sucked after change by user, also by chewing gum air-breathing mist entrance, while the effects of play cleaning oral cavity, pre- anti-caries.
Although the specific embodiment for having referred to the application describes and illustrates that the application, these descriptions and instructions are simultaneously unlimited
The application processed.Those skilled in the art can be clearly understood from, and not depart from this Shen as defined by the appended patent claims
In the case where true spirit please and range, various changes can be carried out, so that particular condition, material, material composition, substance, side
Method or process are suitable for an object of the application, spirit and scope.All such modifications are intended in this appended claims
In range.Although having referred to the specific operation being performed in a specific order describes method disclosed herein, it should be appreciated that can be
These operations are combined, segment or resequenced in the case where the teaching for not departing from the application to form equivalent method.Therefore, unless
Special instructions herein, the order and grouping otherwise operated and not this Applicant's Abstract graph limitation.
Feature in terms of several embodiments and details of foregoing general description the application.Embodiment described in this application can be easy
Ground is used as designing or modifying the basis of other processes and for executing same or similar purpose and/or being incorporated herein
In embodiment same or similar advantage structure.Such equivalent constructions without departing from spirit and scope, and
It can be variously modified, substitute and change in the case where not departing from spirit and scope.
Claims (13)
1. a kind of chewing gum, it includes the substances of following parts by weight:
10 to 50 parts of sweetener, 5 to 20 parts of coolant agent and 15 to 85 parts of propylene glycol；Wherein the sweetener includes xylose
At least one of alcohol, maltose, stevioside, rhamnose, trehalose, antierythrite, lactose and galactolipin.
2. chewing gum according to claim 1, wherein the sweetener includes xylitol.
3. chewing gum according to claim 1 or 2 further comprises the flavor components or Chinese medicine group of 0 to 15 parts by weight
Close object；Wherein the flavor components include at least one in limonene, citral, linalool, magnolol, tea polyphenols and caffeine
Kind and the Chinese medicine composition include at least one of lemon extract, Magnolia cortex P.E and green-tea extract.
4. chewing gum according to claim 1 or 2, wherein the coolant agent include menthol, menthones, isomenthone,
Menthyl lactate, N, 2,3- trimethyl -2- butanamide, N- ethyl-to menthyl -3- formamide,
N- (ethoxycarbonylmethyl group)-is to alkane -3- formamide, N- (4- methoxyphenyl)-thin to menthyl -3- carboxylic acid amides and acetic acid
At least one of lotus ester.
5. chewing gum according to claim 1 or 2, further comprising: the essence of 0.01 to 25 parts by weight.
6. chewing gum according to claim 5, wherein the essence is selected from by australene, benzyl alcohol, benzaldehyde, benzene second
Aldehyde, Ergol, neral, nerol, geraniol, indoles, jasmone, nerolidol, strawberry aldehyde, dihydro jasmone acid first
Ester, dihydroaclinidiolide, eugenol, beta-myrcene, cymene, diethyl sebacate, methyl 2-methylbutyrate, 2- methyl fourth
Acetoacetic ester, ethyl isovalerate, γ-terpinene, γ-terpinol, γ-hexalactone, γ-octalactone, γ-decalactone, γ-Xin Ding
Ester, gamma-undecalactone, γ-dodecalactone, leaf-alcohol, hexanol, amylalcohol, 2,5- dimethyl pyrazine, acid methylester, ethyl cinnamate, second
Base maltol, ethyl isovalerate, melonal, vanillic aldehyde, methyl heptenone, maltol, ethylmaltol, acetic acid 2- methyl fourth
Ester, ethyl acetate, butyl acetate, isoamyl acetate, hexyl acetate, Leaf Acetate, propionic acid, ethyl propionate, ethyl butyrate, 2-
Methylbutanoic acid ethyl ester, myosmine, triacetyl glycerine, linalool oxide, benzyl carbinol, ketoisophorone, cis- 6- nonenol
And combinations thereof composed by group.
7. a kind of electronic cigarette liquid, it includes chewing gums described in any claim in claim 1 to 6.
8. electronic cigarette liquid according to claim 7, it includes the substances of following parts by weight: 0.5 to 20 part of sweetener,
0.25 to 8 part of coolant agent, 0 to 6 part of flavor components or Chinese medicine composition, 0 to 5 part of nicotine salt, 30 to 60 parts sweet
Oil and 10 to 65 parts of propylene glycol；Wherein the flavor components include limonene, citral, linalool, magnolol, tea polyphenols and
At least one of caffeine and the Chinese medicine composition include in lemon extract, Magnolia cortex P.E and green-tea extract
At least one.
9. electronic cigarette liquid according to claim 8, further comprising: the essence of 0.01 to 10 parts by weight.
10. electronic cigarette liquid according to claim 9, wherein the essence is selected from by australene, benzyl alcohol, benzaldehyde, benzene
Acetaldehyde, Ergol, neral, nerol, geraniol, indoles, jasmone, nerolidol, strawberry aldehyde, dihydro jasmone acid
Methyl esters, dihydroaclinidiolide, eugenol, beta-myrcene, cymene, diethyl sebacate, methyl 2-methylbutyrate, 2- methyl
Ethyl butyrate, ethyl isovalerate, γ-terpinene, γ-terpinol, γ-hexalactone, γ-octalactone, γ-decalactone, γ-Xin Ding
Ester, gamma-undecalactone, γ-dodecalactone, leaf-alcohol, hexanol, amylalcohol, 2,5- dimethyl pyrazine, acid methylester, ethyl cinnamate, second
Base maltol, ethyl isovalerate, melonal, vanillic aldehyde, methyl heptenone, maltol, ethylmaltol, acetic acid 2- methyl fourth
Ester, ethyl acetate, butyl acetate, isoamyl acetate, hexyl acetate, Leaf Acetate, propionic acid, ethyl propionate, ethyl butyrate, 2-
Methylbutanoic acid ethyl ester, myosmine, triacetyl glycerine, linalool oxide, benzyl carbinol, ketoisophorone, cis- 6- nonenol
And combinations thereof composed by group.
11. a kind of atomising device, it includes chewing gum described in any claim in claim 1 to 6 or claim 7 or
Electronic cigarette liquid described in 8.
12. atomising device according to claim 9, wherein the atomising device includes electronic cigarette, ultrasonic atomizer or net
Formula atomizer.
13. one kind is according to claim 1 to electronics described in chewing gum described in any claim in 6 or claim 7 or 8
Purposes of the tobacco juice in cleaning oral cavity or pre- anti-caries.
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| CN201910683324.2A CN110419764A (en) | 2019-07-26 | 2019-07-26 | Chewing gum, electronic cigarette liquid and application thereof |
| PCT/CN2019/108302 WO2021017137A1 (en) | 2019-07-26 | 2019-09-26 | Chewing gum, e-liquid and use thereof |
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