CN110338292A - A kind of mixed feed additive and its application - Google Patents

A kind of mixed feed additive and its application Download PDF

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Publication number
CN110338292A
CN110338292A CN201910779268.2A CN201910779268A CN110338292A CN 110338292 A CN110338292 A CN 110338292A CN 201910779268 A CN201910779268 A CN 201910779268A CN 110338292 A CN110338292 A CN 110338292A
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berk
powder
mixed feed
carrier
feed additive
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徐自奥
徐娟娟
曹珊
杨爽
李晓祥
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HEFEI MICRO BIOLOGICAL ENGINEERING Co Ltd
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HEFEI MICRO BIOLOGICAL ENGINEERING Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/20—Inorganic substances, e.g. oligoelements
    • A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87—Re-use of by-products of food processing for fodder production

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
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  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Fodder In General (AREA)

Abstract

The invention discloses a kind of mixed feed additive and its application, which is mainly mixed by Cordyceps gunnii (Berk.) Berk strain fermentation object, γ-aminobutyric acid powder, and/or carrier；It is calculated in mass percent, the dosage of the Cordyceps gunnii (Berk.) Berk strain fermentation object is 40~95%, and the dosage of the γ-aminobutyric acid powder is 5~60%, remaining is carrier.The present invention is by mixing Cordyceps gunnii (Berk.) Berk strain fermentation object and γ-aminobutyric acid powder, obtained mixed feed additive can more effectively reduce the physiological responses to heat stress of livestock and poultry animal, guarantee the normal growth of livestock and poultry animal and the raising of production performance under stress situation, provides more preferably feedstuff additive product for the livestock and poultry animal in physiological responses to heat stress state.

Description

A kind of mixed feed additive and its application
Technical field
The present invention relates to feed addictive preparation technical field more particularly to a kind of mixed feed additive and its answer With.
Background technique
Cordyceps sinensis is the rare fungi-medicine in China and advanced tonic, before the Ming Dynasty, China, it is known that cordyceps sinensis is applied in road； Sensu lato cordyceps sinensis refers to that entomogenous fungi infects the fungus sporophore (stroma) formed after insect or arthropod and insect Or the complex of arthropod.There are about more than 400 for Cordyceps sinensis fungus, wherein that most rare is cordyceps sinensis (Cordyceps It sinensis), is that the linear Cordyceps sinensis fungus of Clavicipitaceae (Ophiocordyceps) parasitizes bat moth category (Hepialus Spp. the complex formed in larva body), is the endemic species of Qinghai-Tibet high altitude localities, is China referred to as " cordyceps sinensis " Traditional rare Chinese medicine.
Currently, the research about cordyceps species and its tunning is many, animal feed additive field can be applied to, Such as: the patent of invention that application notification number is CN103756916B discloses a kind of Acremonium terricola mutant strain and its application, the ground The deposit number of acremonium mutagenic fungi (MKL18) is CCTCC NO.M2013654, is obtained by Uv-induced screening, mycelia Body extract has immunocompetent function in anti tumor activity in vitro and enhancing animal body, can be used for drug and health food Preparation；Mortierella Diding MKL18 consolidates biphasic fermentation by liquid, and tunning can be directly as feed after drying, crushing Additive, the feed addictive not only significantly improve the production performance of weanling pig, but also significantly improve the health of weanling pig Situation.
γ-aminobutyric acid, i.e. 4-Aminobutanoicacid, molecular formula C4H9NO2, relative molecular weight 103.2.In animal body, α-ketoglutaric acid (α-Ketoglutaric acid) generates glutamic acid (Glutamic acid, Glu) through transamination, then Under glutamate decarboxylase (Glutamate decarboxylase, GAD) catalysis, L-Glu decarboxylation generates GABA.And GABA Metabolism is then that transamination occurs with α-ketoglutaric acid and forms succinic acid semialdehyde first under the catalysis of GABA transaminase (Succinate semialdehyde, SSA) and glutamic acid, succinic acid semialdehyde are further converted into succinic acid (SA) into three Carboxylic acid recycle is metabolized.
Heat stress is one of the most important factor for causing animal reproduction performance and immunocompetence to decline, and is caused to aquaculture Huge economic loss.And γ-aminobutyric acid (γ-aminobutyric acid, GABA) is that central nervous system is most important Inhibitory neurotransmitter has the physiological actions such as calmness, blood pressure lowering, anticonvulsion, can adjust the endocrine dysfunction of animal, alleviates The heat stress of animal acts on, to improve the production performance of the animals such as heat stress pig, chicken.
Currently, it is more about the research that γ-aminobutyric acid alleviates Heat stress effect, still, γ-aminobutyric acid and worm The interaction that grass belongs between strain fermentation object but has not been reported.
Summary of the invention
The present invention provides a kind of mixed feed additive and its application, which can effectively promote Into the growth of livestock and poultry animal, and the physiological responses to heat stress of livestock and poultry animal is reduced, is mentioned for the livestock and poultry animal in physiological responses to heat stress state For more preferably feedstuff additive product.
Specific technical solution is as follows:
A kind of mixed feed additive, mainly by Cordyceps gunnii (Berk.) Berk strain fermentation object, γ-aminobutyric acid powder, and/or Carrier mixes；
It is calculated in mass percent, the dosage of the Cordyceps gunnii (Berk.) Berk strain fermentation object is 40~95%, the γ-aminobutyric acid The dosage of powder is 5~60%, remaining is carrier.
The present invention it is found through experiment that, Cordyceps gunnii (Berk.) Berk strain fermentation object is mixed with γ-aminobutyric acid powder, is obtained Mixed feed additive is added in feed after feeding livestock and poultry animal, and the heat stress that can more effectively reduce livestock and poultry animal is anti- It answers, guarantees the normal growth of livestock and poultry animal and the raising of production performance under stress situation, i.e. Cordyceps gunnii (Berk.) Berk strain fermentation object and γ- There are interactions between aminobutyric acid powder.
Further, the Cordyceps gunnii (Berk.) Berk strain fermentation object is obtained after liquid and solid fermentation by Cordyceps gunnii (Berk.) Berk strain ?；The Cordyceps gunnii (Berk.) Berk strain is mortierella Diding.
Preferably, the Cordyceps gunnii (Berk.) Berk strain is mortierella Diding (Acremonium terricola) MKL18CCTCC NO.M 2013654。
Further, the carrier is organic carrier or inorganic carrier；
The organic carrier be wheat flour, peanut shell powder, maize alcohol stillage, degreasing chaff powder, groundnut stem meal, corn protein powder, Soya bean stem meal, corn flour, grass meal, Herba Leonuri granule, leaf powder, fecula, corn germ cake powder, powdered rice hulls, soy meal and corn At least one of core powder；
The inorganic carrier is inorganic salts, is calcium carbonate, silica, vermiculite, zeolite powder, salt, silicate, phosphoric acid At least one of hydrogen calcium and talcum.
Preferably, being calculated in mass percent, the dosage of the Cordyceps gunnii (Berk.) Berk strain fermentation object is 60~90%, described The dosage of γ-aminobutyric acid powder is 10~40%, remaining is carrier.
Preferably, the carrier is magnesium carbonate, silica or Herba Leonuri granule.
Mixed feed additive of the present invention the preparation method comprises the following steps: taking a certain proportion of Cordyceps gunnii (Berk.) Berk strain fermentation Object, γ-aminobutyric acid powder, and/or carrier are mixed, and after mixing, obtain mixed feed additive.
The growth of livestock and poultry animal that the present invention provides mixed feed additives in the case where preparation promotes heat stress environment and anti- The feed addictive of stress ability or the application in feed.
Further, the livestock and poultry animal is pig, chicken or milk cow.
Further, the mixed feed additive by reduce livestock and poultry animal adrenotrophic hormone and cortisol come Improve the anti-heat stress respond of livestock and poultry animal under heat stress environment.
Further, in terms of the quality of the fodder, the additive amount of the mixed feed additive is 0.05~1%.
Compared with prior art, the invention has the following advantages:
The present invention is by mixing Cordyceps gunnii (Berk.) Berk strain fermentation object and γ-aminobutyric acid powder, obtained mixed type Feed addictive can more effectively reduce the physiological responses to heat stress of livestock and poultry animal, guarantee the normal life of livestock and poultry animal under stress situation Long and production performance raising, provides more preferably feedstuff additive product for the livestock and poultry animal in physiological responses to heat stress state.
Specific embodiment
The invention will be further described combined with specific embodiments below, and what is be exemplified below is only specific implementation of the invention Example, but protection scope of the present invention is not limited only to this.
Embodiment 1
1, Cordyceps gunnii (Berk.) Berk strain solid fermentation object is prepared
(1) fermenting microbe: using mortierella Diding (Acremonium terricola) MKL18 separated on Cordyceps gunnii (Berk.) Berk (being purchased from Hefei Maikeluo Biological Engineering Co., Ltd) is as fermentation object.
(2) seed culture:
The culture medium of seed culture are as follows: 600g white granulated sugar, 300g dried silkworm chrysalis meal, 150g peptone, 200g soybean powder, 100g ferment Female powder, 10g MgSO4, 10g KH2PO4, it is dissolved in 20L water, natural pH；121 DEG C of high pressure steam sterilization 30min.
The condition of seed fermentation are as follows: temperature is 25 DEG C, and ventilatory capacity is 1.00L/ (Lmin), and inoculum concentration is 5% (quality point Number), 30L airlift fermentor liquid amount 67%, fermentation time is for 24 hours.
(3) expand culture:
Expand the culture medium of culture are as follows: 6000g white granulated sugar, 3000g dried silkworm chrysalis meal, 1500g peptone, 2000g soybean powder, 1000g yeast powder, 100g MgSO4, 100g KH2PO4, it is dissolved in 200L water, natural pH；121 DEG C of high pressure steam sterilization 30min.
Expand the condition of culture are as follows: temperature is 25 DEG C, and ventilatory capacity is 1.00L/ (Lmin), and inoculum concentration is 10% (quality Score), 300L airlift fermentor liquid amount 67%, fermentation time is for 24 hours.
After the completion of seed culture and expansion culture, mortierella Diding bacterium solution is obtained.
(4) solid culture:
After mortierella Diding bacterium solution and solid medium stirring inoculation (inoculum concentration 15%, mass fraction), it is laid in shallow Disk top fermentation, material thickness 3cm, constant temperature is 25 DEG C, and humidity 70%, fermentation time 120h obtains solid culture Object；
Wherein, the culture medium of solid fermentation are as follows: corn flour 45%, cotton seed meal 5%, wheat wheat-middlings 4%, dregs of beans 30%, wheat Bran 15.8%, magnesium sulfate 0.05%, zinc sulfate 0.05%, potassium dihydrogen phosphate 0.05%, sodium dihydrogen phosphate 0.05%；Natural pH, 121 DEG C of steam sterilizing 1h.
Solid culture is collected, heated-air drying is down to 8wt% hereinafter, crushing pack to moisture at 60 DEG C, and sealing is protected from light Storage, obtains mortierella Diding solid fermentation object.
The component for measuring solid culture made from the present embodiment, as a result shown in table 1.
Table 1
Detection project The detected value of solid culture
Moisture % 6.5
Protein % 22.7
Polysaccharide % 17.2
Adenosine mg/kg 434
Ergosterol mg/kg 652
2, mixed type type feed addictive is prepared
Feed addictive I: the mortierella Diding solid fermentation object of 50 parts by weight and the γ-aminobutyric acid powder of 50 parts by weight are taken It is mixed, obtains feed addictive I.
Feed addictive II: the mortierella Diding solid fermentation object of 50 parts by weight, the γ-aminobutyric acid powder of 20 parts by weight are taken It is mixed with 30 parts by weight Corn powder, obtains feed addictive II.
Feed addictive III: the mortierella Diding solid fermentation object of 90 parts by weight and the γ-aminobutyric acid powder of 10 parts by weight are taken End is mixed, and feed addictive III is obtained.
Feed addictive IV: the mortierella Diding solid fermentation object of 95 parts by weight and the γ-aminobutyric acid powder of 5 parts by weight are taken It is mixed, obtains feed addictive IV.
Embodiment 2
1, growing and fattening pigs are tested
1.1 test process
In the large-scale cultivation group pig farm of Quanjiao, Anhui Province, examination in 30 days by a definite date is carried out to the fattening period pig under hygrothermal environment Test (feeding time is 30 days, test period: on July 30, -2018 years on the 30th June in 2018).
Specific content of the test are as follows:
Take 120 ages in days, weight it is close, it is uniform quality duroc 120 as experimental subjects, be randomly divided into 6 groups, often Group 20.It is fed using feed provided by following test group or control group, the conventional cultivation index for measuring growing and fattening pigs is (flat Equal daily ingestion amount, average daily gain, average feedstuff-meat ratio) and off-test on the day of serum stress index (cortisol (COR) and Cortex hormone of aadrenaline (ACTH))；Wherein, serum stress index detected using enzyme-linked immunosorbent assay.
The specific difference of test group and processing group is as follows:
(1) control group I: basal diet (0.1 ‰ γ-aminobutyric acid containing mass fraction) only is fed, the composition of basal diet It is shown in Table 1；
(2) control Group II: only basal diet (the mortierella Diding solid fermentation object of 2 ‰ embodiment 1 containing mass fraction) is fed；
(3) test group I: the feed addictive I+ basal diet of feeding mass fraction 0.2 ‰；
(4) test group II: the feed addictive II+ basal diet of feeding mass fraction 0.5 ‰；
(5) test group III: the feed addictive III+ basal diet of feeding mass fraction 1 ‰；
(6) test group IV: the feed addictive IV+ basal diet of feeding mass fraction 2 ‰.
1 basal diet of table composition and trophic level (air bells dry basis)
Note: 1) premix provides for every kilogram of daily ration: vitamin A 30000IU, vitamin B130mg, vitamin B6 30mg, vitamin B2168mg, vitamin K375mg, vitamin D3510000IU, vitamin E 23.80IU, vitamin K31.96mg, pantothenic acid 15.00mg, niacin 1108mg, biotin 3.3mg, choline 9.0g, folic acid 19mg, manganese 100mg, zinc 4.0g, Iron 1.0g, copper 1.0g, iodine 0.45mg, selenium 8.0mg, cobalt 30mg.
2) thick protein is measured value, remaining is calculated value.
1.2 test result
Concrete outcome is shown in Table 2.
The influence of 2 different tests group of table and control group to hygrothermal environment fattening period pig production performance
2, broiler trial
2.1 test process
Test in 30 days by a definite date is carried out to the broiler chicken under hygrothermal environment, is tested from August, 2017 in September, -2017.
It is as follows to test particular content:
The Guangxi blueness foot fiber crops broiler chicken that 300 30 ages in days of selection are in a good state of health is randomly divided into 6 groups, every group 50, uses Feed provided by following test group or control group is fed, and the conventional cultivation index for measuring broiler chicken is (average daily gain, flat Equal daily gain, average feedstuff-meat ratio) and off-test on the day of serum stress index (cortisol (COR) and adrenal cortex are sharp Plain (ACTH))；Wherein, serum stress index detected using enzyme-linked immunosorbent assay.
The specific difference of test group and processing group is as follows:
(1) control group I: basal diet (2 ‰ γ-aminobutyric acid containing mass fraction) only is fed, the group prejudice of basal diet Table 1；
(2) control Group II: only basal diet (the mortierella Diding solid fermentation object of 2 ‰ embodiment 1 containing mass fraction) is fed；
(3) test group I: the feed addictive I+ basal diet of feeding mass fraction 0.2 ‰；
(4) test group II: the feed addictive II+ basal diet of feeding mass fraction 0.5 ‰；
(5) test group III: the feed addictive III+ basal diet of feeding mass fraction 1 ‰；
(6) test group IV: the feed addictive IV+ basal diet of feeding mass fraction 2 ‰.
3 basal diet of table composition and trophic level (air bells dry basis)
1) premix provides for every kilogram of daily ration: vitamin A 7715IU, vitamin B14.60mg vitamin B24.40mg Vitamin B64.75mg vitamin B120.02mg, vitamin D33000IU, vitamin E 20IU, vitamin K32mg, pantothenic acid 11.00mg, niacin 10.0mg, biotin 0.10mg, choline 1100mg, folic acid 1.0mg, manganese 80mg, zinc 50mg, iron 30mg, copper 10mg, iodine 0.80mg, selenium 0.15mg.
2) thick protein is measured value, remaining is calculated value.
2.2 test result
Concrete outcome is shown in Table 4.
The influence of meat chicken growth performance under 4 different tests group of table and control group heat stress state
3, milk cow is tested:
3.1 test process
In the large-scale pasture in Heilungkiang, the milk cow under hygrothermal environment is tested, is tested in April, 2019 to 2019 June in year carries out.
It is as follows to test particular content:
Each 50 progress of the close holstein cow such as selection initial stage Milk Production, Body Condition Score, lactation number of days, parity are related Data statistic analysis is fed using feed provided by following test group or control group, and the conventional cultivation for measuring milk cow refers to Serum on the day of mark (average daily milk production, butterfat percnetage, protein ratio, milk sugar rate, total solid and body cell) and off-test It stress index (cortisol (COR) and cortex hormone of aadrenaline (ACTH))；Wherein, serum stress index use Enzyme-linked Immunosorbent Assay Measuring method is detected.
The specific difference of test group and processing group is as follows:
(1) control group I: basal diet (2 ‰ γ-aminobutyric acid containing mass fraction) only is fed, the group prejudice of basal diet Table 1；
(2) control Group II: only basal diet (the mortierella Diding solid fermentation object of 2 ‰ embodiment 1 containing mass fraction) is fed；
(3) test group I: the feed addictive I+ basal diet of feeding mass fraction 0.2 ‰；
(4) test group II: the feed addictive II+ basal diet of feeding mass fraction 0.5 ‰；
(5) test group III: the feed addictive III+ basal diet of feeding mass fraction 1 ‰；
(6) test group IV: the feed addictive IV+ basal diet of feeding mass fraction 2 ‰.
Control group and test group milk cow guarantee that environment is consistent, feeding management is pressed in same cow house during test It operates, be freely eaten and drink water according to pasture old process.
5 basal diet of table composition and trophic level (air bells dry basis)
Note:1Every kilogram of microelement contains: iron 40mg, copper 8mg, manganese 55mg, zinc 20mg, iodine 0.15mg, selenium 0.1mg.
2Every kilogram of multivitamin contains: 54000 000IU of vitamin A, vitamin B12 000IU, vitamin B2 15 000IU, vitamin B67000IU, vitamin B1230mg, vitamin D310 800 000IU, 18 000IU of vitamin E, dimension Raw element K35 000IU, calcium pantothenate 25 000IU, niacin 35000IU, folic acid 500mg, biotin 500mg.
3For diets of different nutrition level in addition to methionine, lysine, other values are measured values.
3.2 test result
Concrete outcome is shown in Table 6.
The influence of 6 different tests group of table and control group to dairy cattle under heat stress state
Embodiment 3
The present embodiment prepares mortierella Diding solid fermentation object using the identical method of embodiment 1；Take the ground top of 40 parts by weight The mould solid fermentation object of spore and the γ-aminobutyric acid powder of 50 parts by weight and the magnesium carbonate powder of 10 parts by weight are mixed, and are obtained Feed addictive.
The feed addictive is added in the basal diet of feeding mutton sheep, additive amount is 0.4 ‰, to add containing 0.4 ‰ The basal diet of the γ-aminobutyric acid powder of dosage is as control；As a result the feed intake of test group, daily gain are above control Group, feedstuff-meat ratio are lower than control group.
Embodiment 4
The present embodiment prepares mortierella Diding solid fermentation object using the identical method of embodiment 1；Take the ground top of 94 parts by weight The mould solid fermentation object of spore and the γ-aminobutyric acid powder of 5 parts by weight and the motherwort powder of 1 parts by weight are mixed, and are raised Feed additives.
The feed addictive is added in the basal diet of feeding laying hen, additive amount is 1 ‰, to contain 1 ‰ additive amounts γ-aminobutyric acid powder basal diet as control；As a result the feed intake of test group, laying rate are above control group, material Egg ratio and shell-breaking rate are lower than control group.

Claims (10)

1. a kind of mixed feed additive, which is characterized in that it is mainly by Cordyceps gunnii (Berk.) Berk strain fermentation object, γ-aminobutyric acid Powder, and/or carrier mix；
It is calculated in mass percent, the dosage of the Cordyceps gunnii (Berk.) Berk strain fermentation object is 40~95%, the γ-aminobutyric acid powder Dosage be 5~60%, remaining is carrier.
2. mixed feed additive as described in claim 1, which is characterized in that the Cordyceps gunnii (Berk.) Berk strain fermentation object is by Gu Buddhist nun's cordyceps species obtain after liquid and solid fermentation；The Cordyceps gunnii (Berk.) Berk strain is mortierella Diding.
3. mixed feed additive as claimed in claim 2, which is characterized in that the Cordyceps gunnii (Berk.) Berk strain is mortierella Diding (Acremonium terricola)MKL18 CCTCC NO.M 2013654。
4. mixed feed additive as described in claim 1, which is characterized in that the carrier is for organic carrier or without airborne Body；
The organic carrier is wheat flour, peanut shell powder, maize alcohol stillage, degreasing chaff powder, groundnut stem meal, corn protein powder, beanstalk Powder, corn flour, grass meal, Herba Leonuri granule, leaf powder, fecula, corn germ cake powder, powdered rice hulls, soy meal and maize cob meal At least one of；
The inorganic carrier is inorganic salts, is calcium carbonate, silica, vermiculite, zeolite powder, salt, silicate, calcium monohydrogen phosphate At least one of with talcum.
5. mixed feed additive as described in claim 1, which is characterized in that be calculated in mass percent, the Gu Buddhist nun worm The dosage of careless strain fermentation object is 60~90%, and the dosage of the γ-aminobutyric acid powder is 10~40%, remaining is carrier.
6. such as the described in any item mixed feed additives of claim 1 or 5, which is characterized in that the carrier is magnesium carbonate Or Herba Leonuri granule.
7. mixed feed additive as described in any one of claims 1 to 6 livestock and poultry in the case where preparation promotes heat stress environment are dynamic The growth of object and the feed addictive of anti-heat stress respond or the application in feed.
8. the use as claimed in claim 7, which is characterized in that the livestock and poultry animal is pig, chicken or milk cow.
9. the use as claimed in claim 7, which is characterized in that the mixed feed additive is by reducing livestock and poultry animal Adrenotrophic hormone and cortisol improve the anti-heat stress respond of livestock and poultry animal under heat stress environment.
10. the use as claimed in claim 7, which is characterized in that in terms of the quality of the fodder, the mixed feed addition The additive amount of agent is 0.05~1%.
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Cited By (5)

* Cited by examiner, † Cited by third party
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CN111227118A (en) * 2020-03-04 2020-06-05 河南全印检测技术有限公司 Green mixed feed additive, preparation method thereof and main component detection method
CN112155135A (en) * 2020-10-21 2021-01-01 安徽科技学院 Feed additive and feed containing same
CN113930464A (en) * 2021-09-22 2022-01-14 湖北华扬科技发展有限公司 Method for producing gamma-aminobutyric acid by using bacillus coagulans and application of method
CN114287530A (en) * 2022-01-10 2022-04-08 清远一生自然生物研究院有限公司 Acremonium terricola culture fermented feed special for suckling pigs and preparation method thereof
CN114651910A (en) * 2021-11-24 2022-06-24 无锡泛宁生物科技有限公司 Feed additive for promoting growth of broiler chickens and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN111227118A (en) * 2020-03-04 2020-06-05 河南全印检测技术有限公司 Green mixed feed additive, preparation method thereof and main component detection method
CN112155135A (en) * 2020-10-21 2021-01-01 安徽科技学院 Feed additive and feed containing same
CN113930464A (en) * 2021-09-22 2022-01-14 湖北华扬科技发展有限公司 Method for producing gamma-aminobutyric acid by using bacillus coagulans and application of method
CN114651910A (en) * 2021-11-24 2022-06-24 无锡泛宁生物科技有限公司 Feed additive for promoting growth of broiler chickens and preparation method thereof
CN114287530A (en) * 2022-01-10 2022-04-08 清远一生自然生物研究院有限公司 Acremonium terricola culture fermented feed special for suckling pigs and preparation method thereof

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Application publication date: 20191018