CN110279603A - A kind of Compositional antiseptic agent and preparation method for cosmetics - Google Patents
A kind of Compositional antiseptic agent and preparation method for cosmetics Download PDFInfo
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- CN110279603A CN110279603A CN201910642429.3A CN201910642429A CN110279603A CN 110279603 A CN110279603 A CN 110279603A CN 201910642429 A CN201910642429 A CN 201910642429A CN 110279603 A CN110279603 A CN 110279603A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of Compositional antiseptic agent and preparation method for cosmetics, the Compositional antiseptic agent is grouped as by the group of following weight percent: lauroyl arginine ethyl ester hydrochloride 1%-20%, surplus are polyalcohol；The preparation method after stirring and evenly mixing, obtains Compositional antiseptic agent comprising steps of weigh the lauroyl arginine ethyl ester hydrochloride and polyalcohol of corrresponding quality according to weight percent.The present invention can inhibit most of bacteriums, fungi and yeasts in cosmetics, also have the function of moisturizing, moisturizing.The present invention has good affinity to skin, suitable for the cosmetics series more demanding to formula mildness.
Description
Technical field
The invention belongs to medicine or cosmetics preservative technical fields, and in particular to a kind of compounding anti-corrosion for cosmetics
Agent and preparation method.
Background technique
For the purpose of cosmetics preservative refers to the growth and breeding to inhibit microorganism in cosmetics and in cosmetics
The substance of addition.Cosmetics preservative has different mode classifications.Common cosmetics preservative has benzyl alcohol, benzoic acid, water
The substances such as poplar acid, boric acid, sorbic acid and other alcohols, aldehydes.The effect of Determination of Preservatives in Cosmetics mainly inhibits microorganism
Growth and breeding, keep cosmetics property stablize, be unlikely to deteriorate after making its use of uncapping, extend the holding time.
Demand of the more cosmetics of moisture to preservative is larger, such as toner, lotion；And closer to ointment or wax
Cosmetics, microorganism is more difficult to survive, and the demand to preservative is relatively small.Usually using several anti-corrosions in Cosmetic Manufacture
Agent is compounded, and is expanded antibacterial range to reach, is improved drug effect, anti-secondary pollution and other effects.
Lauroyl arginine ethyl ester hydrochloride is mainly used for cosmetic industry.It is used in cosmetics as preservative.
The single use lauroyl arginine ethyl ester hydrochloride cosmetics more for moisture can not play preferable antibacterial work at present
With, and it is bad using the preservative fungistatic effect that lauroyl arginine ethyl ester hydrochloride compounds, it is antibacterial not comprehensive enough, it is difficult to
The cosmetics more to moisture play effective antisepsis.
Summary of the invention
In order to solve the above problems existing in the present technology, it is an object of that present invention to provide a kind of compoundings for cosmetics
Preservative and preparation method.
The technical scheme adopted by the invention is as follows:
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 1%-20%, surplus are polyalcohol.
Further, the polyalcohol be Sensiva SC50,1,2 propylene glycol, 1,3 butanediols, 1,3 propylene glycol, 1,2 oneself
Glycol, 1,2 ethohexadiols, 1, one of 2 pentanediols, methyl propanediol, Isosorbide-5-Nitrae butanediol, dipropylene glycol and glycerol or a variety of.
Further, the Compositional antiseptic agent is grouped as by the group of following weight percent: lauroyl arginine ethyl ester salt
Hydrochlorate 10%；Sensiva SC50 5%；1,2 propylene glycol 80% and 1,2 hexylene glycols 5%.
Further, the Compositional antiseptic agent is grouped as by the group of following weight percent: lauroyl arginine ethyl ester salt
Hydrochlorate 10%, 3%, 1,2 propylene glycol of Sensiva SC50,70%, 1,2 hexylene glycol 3% and glycerol 14%.
Further, the Compositional antiseptic agent is grouped as by the group of following weight percent: lauroyl arginine ethyl ester salt
Hydrochlorate 4%, 5%, 1,2 propylene glycol of Sensiva SC50,60%, 1,3 butanediol, 10%, 1,2 hexylene glycol 5%, 1,2 ethohexadiols
11% and 1,2 pentanediols 5%.
Further, the Compositional antiseptic agent is grouped as by the group of following weight percent: lauroyl arginine ethyl ester salt
Hydrochlorate 10%, 10%, 1,2 propylene glycol of Sensiva SC50,50%, 1,2 hexylene glycol 5% and methyl propanediol 25%.
Further, the Compositional antiseptic agent is grouped as by the group of following weight percent: lauroyl arginine ethyl ester salt
Hydrochlorate 20%, 1%, 1,2 propylene glycol 40% of Sensiva SC50 and glycerol 39%.
Further, the Compositional antiseptic agent is grouped as by the group of following weight percent: lauroyl arginine ethyl ester salt
Hydrochlorate 8%, 5%, 1,2 propylene glycol of Sensiva SC50,72%, 1,2 hexylene glycol 5% and 1,2 ethohexadiols 10%.
Further, the Compositional antiseptic agent is grouped as by the group of following weight percent: lauroyl arginine ethyl ester salt
Hydrochlorate 1%, 10%, 1,2 propylene glycol of Sensiva SC50,59%, 1,2 hexylene glycol, 10%, 1,2 ethohexadiol 10% and 1,2 pentanediols
10%.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
The invention has the benefit that a kind of Compositional antiseptic agent and preparation method for cosmetics of the invention by with
Lauroyl arginine ethyl ester hydrochloride is raw material, using polyalcohol be solvent complex at preservative, have extensive active, can have
Effect inhibits gram-positive bacterium, gramnegative bacterium, yeast and mold, and can be excellent in alimentary canal rapid metabolization
Good new food preservative product inhibiting most of bacteriums, fungi and yeasts for not only can control in cosmetics, also having and protecting
Wet, the function of moisturizing has good affinity to skin；Compositional antiseptic agent of the invention have safety, it is mild, suitable for matching
The characteristics of square mildness more demanding cosmetics series.
Specific embodiment
Further explaination is done to the present invention combined with specific embodiments below.
Embodiment 1
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 1%, surplus are polyalcohol.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 2
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 20%, surplus are polyalcohol.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 3
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 6%, surplus are polyalcohol.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 4
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 9%, surplus are polyalcohol.
The polyalcohol is Sensiva SC50,1,2 propylene glycol, 1,3 butanediols, 1,3 propylene glycol, 1,2 hexylene glycols, 1,2
Ethohexadiol, 1,2 pentanediols, methyl propanediol, Isosorbide-5-Nitrae butanediol or glycerol.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 5
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 10%；Sensiva SC50 5%；1,2 propylene glycol 80% and 1,2 hexylene glycols 5%.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 6
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 10%, 3%, 1,2 propylene glycol of Sensiva SC50,70%, 1,2 hexylene glycol 3% and glycerol
14%.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 7
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 4%, 5%, 1,2 propylene glycol of Sensiva SC50,60%, 1,3 butanediol 10%, 1,2 oneself two
5%, 1,2 ethohexadiol 11% and 1 of alcohol, 2 pentanediols 5%.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 8
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 10%, 10%, 1,2 propylene glycol of Sensiva SC50,50%, 1,2 hexylene glycol 5% and methyl
Propylene glycol 25%.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 9
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 20%, 1%, 1,2 propylene glycol 40% of Sensiva SC50 and glycerol 39%.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 10
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 8%, 5%, 1,2 propylene glycol of Sensiva SC50,72%, 1,2 hexylene glycol 5% and 1,2 pungent two
Alcohol 10%.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 11
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 1%, 10%, 1,2 propylene glycol of Sensiva SC50,59%, 1,2 hexylene glycol 10%, 1,2 is pungent
Glycol 10% and 1,2 pentanediols 10%.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Embodiment 12
A kind of Compositional antiseptic agent for cosmetics, the Compositional antiseptic agent are grouped as by the group of following weight percent:
Lauroyl arginine ethyl ester hydrochloride 9%, surplus are polyalcohol.
The polyalcohol is Sensiva SC50,1,2 propylene glycol, 1,3 butanediols, 1,3 propylene glycol, 1,2 hexylene glycols, 1,2
Ethohexadiol, 1,2 pentanediols, methyl propanediol, Isosorbide-5-Nitrae butanediol, dipropylene glycol or glycerol.
A kind of preparation method of the Compositional antiseptic agent for cosmetics, comprising steps of being weighed accordingly according to weight percent
The lauroyl arginine ethyl ester hydrochloride and polyalcohol of quality, after stirring and evenly mixing, obtain Compositional antiseptic agent.
Confirmatory experiment
Bacterium used in this experiment is the Mixed Microbes of Escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, this reality
Fungi used in testing is the Mixed Microbes of aspergillus niger and Candida albicans.
It selects as number is the Compositional antiseptic agent of 1-10, progress Bacterial challenges experiment in the following table 1.
Table 1
Note: "-" expression is not added with.
One, facial mask liquid preservative challenge test
Facial mask liquid proportion such as the following table 2.
Table 2
| Title | Wt% |
| 1,3 butanol | 2 |
| Propylene glycol | 3 |
| Glycerol | 4 |
| 250HHR | 0.3 |
| Amino acid humectant | 1.5 |
| Trehalose | 0.5 |
| Erythrose alcohol | 0.5 |
| Deionized water | 84.3 |
| EDTA-2Na | 0.03 |
| Allantoin | 0.1 |
| Polyglycereol -26 | 1 |
| Hydrolyze Scleroglucan | 0.05 |
| Birch juice extracting solution | 0.5 |
| Tea extract | 0.5 |
| Oat beta-glucan | 0.5 |
| The compound anti-sensitizer of plant | 0.5 |
| Essence | 0.02 |
1, prepare facial mask liquid, be divided into 12 parts；
2, first part of blank facial mask liquid directly detects, not long bacterium；
3, second part of blank facial mask liquid detects after adding bacterium to cultivate two days, and clump count can not mostly be counted；
4, (the corresponding facial mask of preservative substance formula 1 is added in another 10 parts of blank facial mask liquids in 10 parts of Compositional antiseptic agents of above-mentioned table 1
Liquid 1, and so on), following bacteria and mold: 1x10 are added in the sample for having added preservative6cfu/ml Staphylo
coccus aureus ATCC 6538、1x106cfu/ml Pseudomonas aeruginosa ATCC9027、2x106cfu/
ml Escherichia coli ATCC8739、1x106cfu/ml Candida albicans ATCC10231、1x106cfu/
Ml Aspergillus nigre ATCC16404 (imitate the worst production environment) places 7 days, 14 in the incubator of 370C
It, after 28 days, survey clump count respectively.As a result such as the following table 3.
Table 3
As sample at the 7th day containing the bacterium less than 10cfu/ml, and be not further added by, be then considered as logical in the 14th day bacterium
It crosses, otherwise not pass through.
Two, cream preservative challenge test
Cream proportion such as the following table 4.
1, prepare cream, be divided into 12 parts；
2, first part of blank cream directly detects, not long bacterium；
3, second part of blank cream detects after adding bacterium to cultivate two days, and clump count can not mostly be counted；
4, (the corresponding cream of preservative substance formula 1 in the corresponding another 10 parts of blank creams of addition of 10 portions of preservatives of above-mentioned compounding
1) following bacteria and mold: 1x10, are added in the sample for having added preservative6cfu/ml Staphylococcus aureus
ATCC 6538、2x106cfu/ml Pseudomonas aeruginosa ATCC9027、2x106cfu/ml Escherichia
coli ATCC8739、3x106cfu/ml Candida albicans ATCC10231、1x106cfu/ml Aspergillus
Nigre ATCC16404 (imitate the worst production environment), after the incubator of 370C is placed 7 days, 14 days, 28 days, respectively
Survey clump count.As a result such as the following table 5.
Table 4
Table 5
As sample at the 7th day containing the bacterium less than 10cfu/ml, and be not further added by, be then considered as logical in the 14th day bacterium
It crosses, otherwise not pass through.
Three, shampoo preservative challenge test
Shampoo proportion such as the following table 6.
Table 6
1, prepare pure amino acid (no silicone oil) shampoo, be divided into 12 parts；
2, first part of blank shampoo directly detects, not long bacterium；
3, second part of blank shampoo detects after adding bacterium to cultivate two days, and clump count can not mostly be counted；
4, (correspondence of preservative substance formula 1 is washed in the corresponding another 10 parts of blank shampoos of addition of 10 portions of preservatives of above-mentioned compounding
1), in the sample for having added preservative following bacteria and mold: 1x10 are added in shampoo6cfu/ml Staphylococcus
aureus ATCC 6538、2x106cfu/ml Pseudomonas aeruginosa ATCC9027、2x106cfu/ml
Escherichia coli ATCC8739、3x106cfu/ml Candida albicans ATCC10231、1x106cfu/ml
Aspergillus nigre ATCC16404 (imitate the worst production environment), 370C incubator place 7 days, 14 days,
After 28 days, clump count is surveyed respectively.As a result such as the following table 7.
Table 7
As sample at the 7th day containing the bacterium less than 10cfu/ml, and be not further added by, be then considered as logical in the 14th day bacterium
It crosses, otherwise not pass through.
To sum up, Compositional antiseptic agent of the invention can effectively inhibit gram-positive bacterium, gramnegative bacterium, mould and
Saccharomycete is excellent new food preservative product.Compositional antiseptic agent of the invention is big for not only can control inhibition in cosmetics
Most bacteriums, fungi and yeasts, also have moisturizing, and the function of moisturizing has good affinity to skin；Compounding of the invention
Preservative have the characteristics that safety, it is mild, suitable for the cosmetics series more demanding to formula mildness.
The present invention is not limited to above-mentioned optional embodiment, anyone can show that other are each under the inspiration of the present invention
The product of kind form.Above-mentioned specific embodiment should not be understood the limitation of pairs of protection scope of the present invention, protection of the invention
Range should be subject to be defined in claims, and specification can be used for interpreting the claims.
Claims (10)
1. a kind of Compositional antiseptic agent for cosmetics, it is characterised in that: the Compositional antiseptic agent is by following weight percent
Group is grouped as: lauroyl arginine ethyl ester hydrochloride 1%-20%, surplus are polyalcohol.
2. a kind of Compositional antiseptic agent for cosmetics according to claim 1, it is characterised in that: the polyalcohol is second
Base hexyl glycerol, 1,2 propylene glycol, 1,3 butanediols, 1,3 propylene glycol, 1,2 hexylene glycols, 1,2 ethohexadiols, 1,2 pentanediols, methyl-prop
One of glycol, Isosorbide-5-Nitrae butanediol, dipropylene glycol and glycerol are a variety of.
3. a kind of Compositional antiseptic agent for cosmetics according to claim 2, it is characterised in that: the Compositional antiseptic agent
It is grouped as by the group of following weight percent: lauroyl arginine ethyl ester hydrochloride 10%；Sensiva SC50 5%；1,2 the third two
Alcohol 80% and 1,2 hexylene glycols 5%.
4. a kind of Compositional antiseptic agent for cosmetics according to claim 2, it is characterised in that: the Compositional antiseptic agent
It is grouped as by the group of following weight percent: lauroyl arginine ethyl ester hydrochloride 10%, Sensiva SC50 3%, 1,2 the third two
70%, 1,2 hexylene glycol 3% of alcohol and glycerol 14%.
5. a kind of Compositional antiseptic agent for cosmetics according to claim 2, it is characterised in that: the Compositional antiseptic agent
It is grouped as by the group of following weight percent: lauroyl arginine ethyl ester hydrochloride 4%, Sensiva SC50 5%, 1,2 the third two
60%, 1,3 butanediol of alcohol, 10%, 1,2 hexylene glycol, 5%, 1,2 ethohexadiol 11% and 1,2 pentanediols 5%.
6. a kind of Compositional antiseptic agent for cosmetics according to claim 2, it is characterised in that: the Compositional antiseptic agent
It is grouped as by the group of following weight percent: lauroyl arginine ethyl ester hydrochloride 10%, Sensiva SC50 10%, 1,2 third
50%, 1,2 hexylene glycol 5% of glycol and methyl propanediol 25%.
7. a kind of Compositional antiseptic agent for cosmetics according to claim 2, it is characterised in that: the Compositional antiseptic agent
It is grouped as by the group of following weight percent: lauroyl arginine ethyl ester hydrochloride 20%, Sensiva SC50 1%, 1,2 the third two
Alcohol 40% and glycerol 39%.
8. a kind of Compositional antiseptic agent for cosmetics according to claim 2, it is characterised in that: the Compositional antiseptic agent
It is grouped as by the group of following weight percent: lauroyl arginine ethyl ester hydrochloride 8%, Sensiva SC50 5%, 1,2 the third two
72%, 1,2 hexylene glycol 5% and 1 of alcohol, 2 ethohexadiols 10%.
9. a kind of Compositional antiseptic agent for cosmetics according to claim 2, it is characterised in that: the Compositional antiseptic agent
It is grouped as by the group of following weight percent: lauroyl arginine ethyl ester hydrochloride 1%, Sensiva SC50 10%, 1,2 the third two
59%, 1,2 hexylene glycol of alcohol, 10%, 1,2 ethohexadiol 10% and 1,2 pentanediols 10%.
10. a kind of a kind of preparation method of the Compositional antiseptic agent for cosmetics described in any one of claim 1-9, special
Sign is, comprising steps of weighing the lauroyl arginine ethyl ester hydrochloride and polyalcohol of corrresponding quality according to weight percent, stirs
After mixing mixing, Compositional antiseptic agent is obtained.
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Cited By (4)
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| CN110840767A (en) * | 2019-12-30 | 2020-02-28 | 福州百草堂医药科技有限公司 | Preservative composition and preparation method and application thereof |
| CN111135108A (en) * | 2020-01-15 | 2020-05-12 | 广东迪美生物技术有限公司 | Compound preservative containing amino acid derivatives, preparation method thereof and cosmetics |
| CN112156023A (en) * | 2020-11-05 | 2021-01-01 | 广州市科能化妆品科研有限公司 | Makeup removing gel and preparation method thereof |
| CN112545916A (en) * | 2020-12-15 | 2021-03-26 | 金发拉比妇婴童用品股份有限公司 | Mild surfactant system and application thereof |
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| 黄淑娟等: "Everpro系列防腐剂性能测试", 《日用化学品科学》 * |
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| CN110840767A (en) * | 2019-12-30 | 2020-02-28 | 福州百草堂医药科技有限公司 | Preservative composition and preparation method and application thereof |
| CN111135108A (en) * | 2020-01-15 | 2020-05-12 | 广东迪美生物技术有限公司 | Compound preservative containing amino acid derivatives, preparation method thereof and cosmetics |
| CN112156023A (en) * | 2020-11-05 | 2021-01-01 | 广州市科能化妆品科研有限公司 | Makeup removing gel and preparation method thereof |
| CN112156023B (en) * | 2020-11-05 | 2023-06-02 | 广州市科能化妆品科研有限公司 | Cleansing gel and preparation method thereof |
| CN112545916A (en) * | 2020-12-15 | 2021-03-26 | 金发拉比妇婴童用品股份有限公司 | Mild surfactant system and application thereof |
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Application publication date: 20190927 |