CN106538592A - A kind of mixture disinfectant for aquaculture - Google Patents
A kind of mixture disinfectant for aquaculture Download PDFInfo
- Publication number
- CN106538592A CN106538592A CN201610927841.6A CN201610927841A CN106538592A CN 106538592 A CN106538592 A CN 106538592A CN 201610927841 A CN201610927841 A CN 201610927841A CN 106538592 A CN106538592 A CN 106538592A
- Authority
- CN
- China
- Prior art keywords
- mixture
- disinfectant
- aquaculture
- aquaculture according
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
- A01N57/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/50—Treatment of water, waste water, or sewage by addition or application of a germicide or by oligodynamic treatment
Abstract
The present invention relates to a kind of mixture disinfectant for aquaculture, it is made up of isothiazolinone biocide agent, quaternary phosphonium bactericide, o-phthalaldehyde(OPA), dispersant, cosolvent, antifreezing agent, stabilizer etc., reactor mix homogeneously is proportionally used during preparation, that is, is obtained the mixture disinfectant for being used for aquaculture.The present invention is by the compounded technology of antibacterial, the advantage of various component things is played, the broad spectrum activity of product is improved, product Drug resistance is reduced, the zest and corrosivity of product are reduced, the sterilizing rate for efficiently solving the problems, such as to use in the past medicament presence is not high, Drug resistance is not strong.The processing of the present invention and easy to use, low price, are respectively provided with to common aquatic pathogenic bacterium.
Description
Technical field
Present invention belongs to the preparing technical field of agro-ecology preparation, is related to a kind of mixture for aquaculture and disappears
Poisoning microbial inoculum, the mixture disinfectant are particularly well-suited to prevent and treat aquatic animal bacterial disease.
Background technology
China is aquaculture big country, and breed variety is numerous, and cultured output accounts for the 70% of whole world aquaculture total amount
Left and right.But the environmental pollution that the rapid expansion along with cultivation scale, regional carrying capacity transfinite and be on the rise, causes
Domestic breeding ecological environment deteriorates increasingly, and the germplasm for adding many traditional breed varieties is degenerated, and premunition declines, and causes cultivation again
The disease incidence of thing day by day increases, and its cause of disease is more based on bacterial disease, and above-mentioned disease becomes restriction China Aquatic product and supports
Grow the key factor of sound development.
It is the harm to anti-disease, in the past to being prevented and treated using antibiotic, disinfectant etc. more than aquaculture thing.It is anti-
Raw element early stage using effect is preferable, but drug effect can fade away with access times, and main cause is biology drug resistance.Disinfection
Agent is the Common drugs of existing Aquatic product diseases prevention and treatment, and huge number, using method are different, are applied at present in modern aquaculture
The extensive Aquatic product disinfectant of comparison mainly has aldehydes, quaternary ammonium salt and halogen disinfectant.But above-mentioned disinfection
In agent, the toxicity of aldehydes disinfectant is larger, has pollution to environment；Halogen disinfectant is mostly chloride, iodine, bromine etc. strong
The chemicals of oxidant, corrosivity and zest are relatively strong, and safety coefficient is low, once drug dose control is not proper will prestige
Coerce the existence of aquaculture thing；Quaternary ammonium disinfectant belongs to cationic surfactant, can be used for anti-corrosion of sterilizing, with valency
The cheap advantage of lattice, but with life-time service, can also make aquaculture thing have very strong Drug resistance.
The content of the invention
It is an object of the invention to solve to the problem that prior art is present, there is provided a kind of for the mixed of aquaculture
With disinfectant, by the compounded technology of the disinfectant, the advantage of various component things is played, improve the wide spectrum of product
Property, product Drug resistance is reduced, the zest and corrosivity of product is reduced.
The technical solution adopted to realize above goal of the invention is as described below.
A kind of mixture disinfectant for aquaculture, it is characterised in that its material group by following mass percents
It is grouped into：
The preparation method of the mixture disinfectant is：In proportion by isothiazolinone biocide agent, o-phthalaldehyde(OPA), point
Powder, cosolvent are added in reactor, add quaternary phosphonium bactericide mix homogeneously, be eventually adding stabilizer, antifreezing agent and
Appropriate pure water, gets product.
In the above-mentioned mixture disinfectant for aquaculture, isothiazolinone biocide agent is chlormethylisothiazo,ine
The mixture of ketone and Methylisothiazolinone, active component content is 14%.
In the above-mentioned mixture disinfectant for aquaculture, quaternary phosphonium bactericide is tetrakis hydroxymetyl phosphonium sulfuric or 14
Alkyl tributyl phosphorus chloride.
In the above-mentioned mixture disinfectant for aquaculture, dispersant be NP-10, Tween 80, EL80, agriculture breast 33#,
The mixture of one or more arbitrary proportions in Nongru-700 #, agriculture breast 600#.
In the above-mentioned mixture disinfectant for aquaculture, cosolvent is methanol, butanol, Ketohexamethylene, dimethyl methyl
The mixture of one or more arbitrary proportions in amide.
In the above-mentioned mixture disinfectant for aquaculture, antifreezing agent is ethylene glycol, Propylene Glycol, in glycerol one
The mixture of kind or several arbitrary proportions.
In the above-mentioned mixture disinfectant for aquaculture, stabilizer is hexamethylenetetramine and/or dihydroxymethyl
Hydantoin.
In the preparation recipe of the present invention, isothiazolinone biocide agent has strong antibacterial, lasting medicine, environment is pacified
The premium properties such as complete and antimicrobial spectrum broadness, were used widely in the industry such as industry, agricultural, medicine in the past, but different thiophene
Oxazoline ketone can produce the stimulation sex chromosome mosaicism to skin in exclusive use；Quaternary alkylphosphonium salt is similar to that quaternary amine, due to phosphorus original
Sub- radius ratio carbon atom is big, and polarization is higher so that quaternary alkylphosphonium salt is more easy to the antibacterial for adsorbing negatively charged son, therefore quaternary alkylphosphonium salt sterilization
The sterilizing rate of agent is better than quaternary ammonium salt antibacterial, in addition by the mixture with quaternary alkylphosphonium salt, also reduces isothiazolinone biocide agent
Zest and corrosivity；O-phthalaldehyde(OPA) is a kind of highly effective and safe antibiosis and sterilization agent, and which is to bacterial propagule, yeast and thin
Bacterium spore has good killing effect, and stable performance, and corrosivity are little.
Compared with prior art, the invention has the beneficial effects as follows：
1) present invention is solved now with aldehydes, quaternary ammonium salt and halogen etc. using the synergism between various antibacterial
Drug resistance produced by disinfectant and broad spectrum activity deficiency problem, common aquatic pathogenic bacterium is respectively provided with significantly suppress and
Killing activity；
2) present invention quaternary phosphonium bactericide instead of traditional quaternary ammonium salt disinfectant, improves drug effect, reduces
The Drug resistance of material culture product；
3) by the mixture with quaternary alkylphosphonium salt, and the effect of various auxiliary agents, the thorn of isothiazolinone biocide agent can be reduced
Sharp property and corrosivity, improve safety, facilitate processing and use, low price；
4) mixture disinfectant of the present invention it is environmentally friendly, to person poultry safety, low toxicity, environmental protection.
Specific embodiment
The invention will be further described with reference to embodiments, but the practical application form of the present invention is not limited to
Following embodiments.
Embodiment 1
A kind of mixture disinfectant for aquaculture, concrete composition are shown in Table 1：
Table 1
Preparation method：By isothiazolone 15kg, o-phthalaldehyde(OPA) 2kg, Ketohexamethylene 5kg, Tween 80 6kg, NP-10
3kg mix homogeneously, adds myristyl tributyl phosphorus chloride 15kg mix homogeneously, is eventually adding hexamethylenetetramine 5kg, and third
Glycol 5kg and appropriate pure water, obtain 100kg products.
The product of prepared 1 formula of embodiment is light yellow transparent liquid, and it is floating that Jing water dilutes 200 times of placements, 2 hours nothings
Oil precipitation.0 ± 2 DEG C stores 7 days, and 54 ± 2 DEG C store 14 days, and outward appearance is without significant change.54 ± 2 DEG C of storages, 14 days resolution ratios are little
In 5%.
After above-mentioned disinfectant medicinal liquid is diluted according to 300～500 times, sterilization of instruments, Fish are can be directly used forBath,
Fishpond sterilizing.
Embodiment 2
A kind of mixture disinfectant for aquaculture, concrete composition are shown in Table 2：
Table 2
Preparation method：By isothiazolone 50kg, o-phthalaldehyde(OPA) 2kg, dimethylformamide 5kg, EL80 6kg, agriculture breast
700#4kg mix homogeneously, adds myristyl tributyl phosphorus chloride 33kg mix homogeneously, obtains 100kg products.
The product of prepared 2 formula of embodiment is light yellow transparent liquid, and it is floating that Jing water dilutes 200 times of placements, 2 hours nothings
Oil precipitation.0 ± 2 DEG C stores 7 days, and 54 ± 2 DEG C store 14 days, and outward appearance is without significant change.54 ± 2 DEG C storage 14 days resolution ratios be
2.5%.
The sex pheromone of fish disease is caused to have a lot, such as vibrio, Aeromonass, mycete etc..Above-mentioned disinfectant
Medicinal liquid is shown in Table 3 to fish bacterial pathogenses bactericidal effect measurement result：
Table 3
| Pathogenic bacteria | Extension rate | Bacteriostasis rate |
| Vibrio | 1000 | 88.1% |
| Aeromonass | 1000 | 94.5% |
| Water mo(u)ld | 1000 | 99.8% |
During use, disinfectant medicinal liquid and 1000 times of water mixed diluting, every mu of water surface are splashed into 20 liters.Through
Animal medicinal liquid company limited of Shanxi universe Thailand tries out, and works well, and in fish pond, all kinds of fish disease conditions are greatly reduced, without outburst compared with
Big pandemic.
Embodiment 3
A kind of mixture disinfectant for aquaculture, concrete composition are shown in Table 4：
Table 4
| Composition | Content (%) |
| Isothiazolone | 15 |
| Tetrakis hydroxymetyl phosphonium sulfuric | 50 |
| O-phthalaldehyde(OPA) | 2 |
| Agriculture breast 33# | 8.0 |
| Ketohexamethylene | 5.0 |
| Hexamethylenetetramine | 5.0 |
| Pure water | Supply 100.0 |
Preparation method：By isothiazolone 15kg, o-phthalaldehyde(OPA) 2kg, Ketohexamethylene 5kg, agriculture breast 33#8kg mix homogeneously,
Tetrakis hydroxymetyl phosphonium sulfuric 50kg mix homogeneously is added, hexamethylenetetramine 5kg and appropriate pure water is eventually adding, is obtained 100kg
Product.
The product of prepared 3 formula of embodiment is light yellow transparent liquid, and it is floating that Jing water dilutes 200 times of placements, 2 hours nothings
Oil precipitation.0 ± 2 DEG C stores 7 days, and 54 ± 2 DEG C store 14 days, and outward appearance is without significant change.54 ± 2 DEG C storage 14 days resolution ratios be
2.28%.
Above-mentioned disinfectant medicinal liquid is shown in Table 5 to Fish virulence measurement result：
Table 5
During use, disinfectant medicinal liquid and 1000 times of water mixed diluting, every mu of water surface are splashed into 20 liters.Through Shanxi
Wei Shi Yu Kang Industrial Co., Ltd.s try out, and have preferable effect, and biological clay stripping well to all kinds of fish diseasess in fish pond
Fall effect, peels off effect up to more than 90%.
Claims (7)
1. a kind of mixture disinfectant for aquaculture, it is characterised in that its material composition by following mass percents
Composition：
The preparation method of the mixture disinfectant is：In proportion by isothiazolinone biocide agent, o-phthalaldehyde(OPA), dispersion
Agent, cosolvent are added in reactor, add quaternary phosphonium bactericide mix homogeneously, are eventually adding stabilizer, antifreezing agent and are fitted
The pure water of amount, gets product.
2. the mixture disinfectant for aquaculture according to claim 1, it is characterised in that described isothiazole
Quinoline ketone antibacterial is the mixture of chlormethylisothiazo,ine ketone and Methylisothiazolinone, and active component content is 14%.
3. the mixture disinfectant for aquaculture according to claim 1, it is characterised in that described quaternary alkylphosphonium salt
Antibacterial is tetrakis hydroxymetyl phosphonium sulfuric or myristyl tributyl phosphorus chloride.
4. the mixture disinfectant for aquaculture according to claim 1, it is characterised in that described dispersant
For the mixture of one or more arbitrary proportions in NP-10, Tween 80, EL80, agriculture breast 33#, Nongru-700 #, agriculture breast 600#.
5. the mixture disinfectant for aquaculture according to claim 1, it is characterised in that described cosolvent
For the mixture of one or more arbitrary proportions in methanol, butanol, Ketohexamethylene, dimethylformamide.
6. the mixture disinfectant for aquaculture according to claim 1, it is characterised in that described antifreezing agent
For the mixture of one or more arbitrary proportions in ethylene glycol, Propylene Glycol, glycerol.
7. the mixture disinfectant for aquaculture according to claim 1, it is characterised in that described stabilizer
For hexamethylenetetramine and/or dihydroxymethyl hydantoin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610927841.6A CN106538592A (en) | 2016-10-31 | 2016-10-31 | A kind of mixture disinfectant for aquaculture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610927841.6A CN106538592A (en) | 2016-10-31 | 2016-10-31 | A kind of mixture disinfectant for aquaculture |
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| Publication Number | Publication Date |
|---|---|
| CN106538592A true CN106538592A (en) | 2017-03-29 |
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ID=58392400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610927841.6A Pending CN106538592A (en) | 2016-10-31 | 2016-10-31 | A kind of mixture disinfectant for aquaculture |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107467084A (en) * | 2017-06-22 | 2017-12-15 | 安徽省黄淮兽药有限公司 | A kind of special disinfectant for aquaculture and its preparation |
| CN107982271A (en) * | 2017-11-22 | 2018-05-04 | 湖北首祥生物科技有限公司 | A kind of desinsection used for aquiculture and bleeding medicine, its preparation method and application |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10273408A (en) * | 1996-11-27 | 1998-10-13 | K I Kasei Kk | Microbicidal composition and control of microbe |
| JP2000290112A (en) * | 1999-04-01 | 2000-10-17 | Kurita Water Ind Ltd | Germicidal composition for industry use and antibiotic treatment |
| CN1711841A (en) * | 2004-06-15 | 2005-12-28 | 常州市武进精细化工厂 | Algicide and bactericidal composition |
| CN101161070A (en) * | 2006-10-13 | 2008-04-16 | 广东海洋大学 | Double chain quaternary ammonium salt complex phthalic two methylene oxide disinfectant |
| US20130251822A1 (en) * | 2009-09-09 | 2013-09-26 | Howard Martin | Biocidal aldehyde composition |
-
2016
- 2016-10-31 CN CN201610927841.6A patent/CN106538592A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10273408A (en) * | 1996-11-27 | 1998-10-13 | K I Kasei Kk | Microbicidal composition and control of microbe |
| JP2000290112A (en) * | 1999-04-01 | 2000-10-17 | Kurita Water Ind Ltd | Germicidal composition for industry use and antibiotic treatment |
| CN1711841A (en) * | 2004-06-15 | 2005-12-28 | 常州市武进精细化工厂 | Algicide and bactericidal composition |
| CN101161070A (en) * | 2006-10-13 | 2008-04-16 | 广东海洋大学 | Double chain quaternary ammonium salt complex phthalic two methylene oxide disinfectant |
| US20130251822A1 (en) * | 2009-09-09 | 2013-09-26 | Howard Martin | Biocidal aldehyde composition |
Non-Patent Citations (1)
| Title |
|---|
| 喻运珍 等: "28种杀菌剂对水霉菌的毒力测定", 《当代水产》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107467084A (en) * | 2017-06-22 | 2017-12-15 | 安徽省黄淮兽药有限公司 | A kind of special disinfectant for aquaculture and its preparation |
| CN107982271A (en) * | 2017-11-22 | 2018-05-04 | 湖北首祥生物科技有限公司 | A kind of desinsection used for aquiculture and bleeding medicine, its preparation method and application |
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Application publication date: 20170329 |
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