CN107714497A - A kind of no added preservative used for cosmetic - Google Patents

A kind of no added preservative used for cosmetic Download PDF

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Publication number
CN107714497A
CN107714497A CN201711222107.0A CN201711222107A CN107714497A CN 107714497 A CN107714497 A CN 107714497A CN 201711222107 A CN201711222107 A CN 201711222107A CN 107714497 A CN107714497 A CN 107714497A
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CN
China
Prior art keywords
added preservative
preservative used
cosmetic according
cosmetic
decoyl hydroximic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711222107.0A
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Chinese (zh)
Inventor
许柄銮
李于波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nox Bellcow Cosmetics Co Ltd
Original Assignee
Nox Bellcow Cosmetics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nox Bellcow Cosmetics Co Ltd filed Critical Nox Bellcow Cosmetics Co Ltd
Priority to CN201711222107.0A priority Critical patent/CN107714497A/en
Publication of CN107714497A publication Critical patent/CN107714497A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/524—Preservatives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention belongs to cosmetic technical field, and in particular to a kind of no added preservative of new cosmetics.Protective system percentage composition in formula is applied is as follows：The propane diols 0.1% -0.5% of methyl propanediol 6.0% -10.0%, 1,2 pentanediols 1.0% -2.0%, 1,2 hexylene glycols 0.3% -0.8%, decoyl hydroximic acid/1,3, EDETATE SODIUM 0.05%.It is an advantage of the invention that：1) traditional preservatives and bactericide are free of, is the compound system for being used in cosmetics to support " no added preservative " concept completely；2) have the characteristics that safe and non-toxic, non-stimulated, can not easily cause the discomfort of skin directly as aseptic applications in the daily cosmetics of various formulations, be adapted to various people.

Description

A kind of no added preservative used for cosmetic
Technical field
The invention belongs to cosmetic technical field, and in particular to the no added protective system of a kind of new cosmetics and its should With.
Background technology
1st, preservative is by killing or suppressing microbial growth, so as to reach prevent from going bad, the purpose of corruption.Preservative one As reach corrosion-resistant effect in the following manner, by disturbing the enzyme system of microorganism, its normal metabolism is destroyed, so as to press down The activity of enzyme processed；Make protein coagulating and the denaturation of microorganism, disturb it to survive and breed；Change cytoplasm permeability of the membrane, Suppress the exclusion of its internal enzyme and metabolite, cause its inactivation.
2nd, preservative is added in cosmetics primarily to reducing the product caused external world in the production and use process Microorganism pollution, quality assurance is provided for the quality of cosmetics.The preservative that now although many cosmetics use is according to rule Model requires addition, but still has a few consumers to cause stimulation, or even allergy.
3rd, at present, existing sterilization antiseptic used for cosmetic is various in style, wherein with formaldehyde and Form aldehyde release body, Bu Luobo You and parabens etc. are most widely used.But conventional traditional preservatives have the following disadvantages：(1) formaldehyde and formaldehyde Potential carcinogenicity be present in releaser；(2) Bronopol easily forms Carcinogenic Nitrosamines；(3) organic halogen composition has potentially Sensitization is present；(4) potential estrogen and androgen are relevant with mastocarcinoma in parabens, there is its taboo of regulation in the product With with the amount of limiting the use of.
4th, therefore, realize that safe and efficient no added protective system increasingly turns into real market and pointed in cosmetics. As under the upsurge impact of back to nature, enjoyment green with health, the requirement in cosmetics to protective system is more next in recent years Higher, how to develop safe and efficient no added protective system turns into the focus of attention both domestic and external.
The content of the invention
The purpose of the present invention is：A kind of the defects of in order to overcome prior art, there is provided no added anti-corrosion used for cosmetic Agent, and splendid inhibition is respectively provided with to bacterium and fungi.
It is another object of the present invention to：A kind of no added aseptic applications used for cosmetic are to elite formula of liquid, to emulsion Or in cream.
What the present invention was realized in：A kind of no added preservative used for cosmetic, its percentage by weight being formulated are：
Methyl propanediol：6.0% -10.0%,
1,2- pentanediols：1.0% -2.0%,
1,2- hexylene glycols：0.3% -0.8%,
Decoyl hydroximic acid/1,3- propane diols：0.1% -0.5%,
EDETATE SODIUM：0.05%.
A kind of application of no added preservative used for cosmetic, it is characterised in that：Essence recipe ingredient percentage by weight For：
A phases：
Deionized water：68.87% -86.32%,
Glycerine：4.0% -10%,
Allantoin：0.10% -0.5%,
Xanthans：0.03% -0.08%,
AVC：0.1% -0.2%,
B phases：
Glycine betaine：1.0% -3.0%,
Niacinamide：1.0% -4.0%,
C phases：Preservative；
Each raw material weight percentage sum is 100% above.
Using no added preservative used for cosmetic Essence its preparation method according to the following steps：
(1) aqueous phase pot temperature is arranged to 80 DEG C, opens stirring 40r/min, be slowly added to A groups successively under stirring Middle each component, stir to water white transparency state；
(2) after the completion of said process, aqueous phase pot opens cooling, when temperature is near 45 DEG C, adds B group raw materials, stirring is equal It is even；
(3) after the completion of said process, C group raw materials is added, are stirred；
(4) when temperature is near 35 DEG C, after continuing stirring 15 minutes, discharging, indices are determined；
(5) can be carried out after indices are qualified filling.
For the present invention compared with existing product, the present invention possesses advantages below：
(1) protective system of the present invention is using polyalcohols such as methyl propanediol, 1,2- pentanediols, 1,2- hexylene glycols, except having Outside antisepsis, moistening effect is also equipped with, and can be used in the cosmetics such as facial mask, emulsion, cream.
(2) the decoyl hydroximic acid that protective system of the present invention uses is a kind of organic acid, in addition, also by chelation and short The growth and breeding that chained list work acts on disturbing and suppressing microorganism, there is excellent antibacterial, bacteriostasis property, and property is gentle not Stimulate.
Embodiment
With reference to embodiment, the invention will be further described.
Embodiment 1：
A kind of no added preservative used for cosmetic is applied in Essence, and its percentage by weight being formulated is：A phases：
Deionized water：83.75%, glycerine：4.0%,
Allantoin：0.20%, xanthans：0.05% -0.08%,
AVC：0.15%；
B phases：
Glycine betaine：2%,
Niacinamide：1.0%,
C phases：
Methyl propanediol：6.0%, 1,2- pentanediol：1.3%,
1,2- hexylene glycols：0.7%, decoyl hydroximic acid/1,3-PD：0.5%,
EDETATE SODIUM：0.05%.
Technical process：
(1) aqueous phase pot temperature is arranged to 80 DEG C, opens stirring 40r/min, be slowly added to A groups successively under stirring Middle each component, stir to water white transparency state；
(2) after the completion of said process, aqueous phase pot opens cooling, when temperature is near 45 DEG C, adds B group raw materials, stirring is equal It is even；
(3) after the completion of said process, C group raw materials is added, are stirred；
(4) when temperature is near 35 DEG C, after continuing stirring 15 minutes, discharging, indices are determined；
(5) can be carried out after indices are qualified filling.
Embodiment 2：
A kind of no added preservative used for cosmetic is applied in Essence, and its percentage by weight being formulated is：A phases：
Deionized water：80.92%, glycerine：6.0%,
Allantoin：0.10%, xanthans：0.03%,
AVC：0.20%；
B phases：
Glycine betaine：1.5%,
Niacinamide：2.0%,
C phases：
Methyl propanediol：7.0%, 1,2- pentanediol：1.8%,
1,2- hexylene glycols：0.5%, decoyl hydroximic acid/1,3-PD：0.2%,
EDETATE SODIUM：0.05%.
Technical process：
(1) aqueous phase pot temperature is arranged to 80 DEG C, opens stirring 40r/min, be slowly added to A groups successively under stirring Middle each component, stir to water white transparency state；
(2) after the completion of said process, aqueous phase pot opens cooling, when temperature is near 45 DEG C, adds B group raw materials, stirring is equal It is even；
(3) after the completion of said process, C group raw materials is added, are stirred；
(4) when temperature is near 35 DEG C, after continuing stirring 15 minutes, discharging, indices are determined；
(5) can be carried out after indices are qualified filling.
Embodiment 3：
A kind of no added preservative used for cosmetic is applied in Essence, and its percentage by weight being formulated is：A phases：
Deionized water：76.67%, glycerine：8.0%,
Allantoin：0.3%, xanthans：0.06%,
AVC：0.12%；
B phases：
Glycine betaine：3%,
Niacinamide：2.0%,
C phases：
Methyl propanediol：8.0%, 1,2- pentanediol：1.0%,
1,2- hexylene glycols：0.5%, decoyl hydroximic acid/1,3-PD：0.3%,
EDETATE SODIUM：0.05%.
Technical process：
(1) aqueous phase pot temperature is arranged to 80 DEG C, opens stirring 40r/min, be slowly added to A groups successively under stirring Middle each component, stir to water white transparency state；
(2) after the completion of said process, aqueous phase pot opens cooling, when temperature is near 45 DEG C, adds B group raw materials, stirring is equal It is even；
(3) after the completion of said process, C group raw materials is added, are stirred；
(4) when temperature is near 35 DEG C, after continuing stirring 15 minutes, discharging, indices are determined；
(5) can be carried out after indices are qualified filling.
Embodiment 4：
A kind of no added preservative used for cosmetic is applied in Essence, and its percentage by weight being formulated is：A phases：
Deionized water：70.67%, glycerine：10%,
Allantoin：0.5%, xanthans：0.08%,
AVC：0.10%；
B phases：
Glycine betaine：3%,
Niacinamide：4.0%,
C phases：
Methyl propanediol：10%, 1,2- pentanediol：1.2%,
1,2- hexylene glycols：0.3%, decoyl hydroximic acid/1,3-PD：0.1%,
EDETATE SODIUM：0.05%.
Technical process：
(1) aqueous phase pot temperature is arranged to 80 DEG C, opens stirring 40r/min, be slowly added to A groups successively under stirring Middle each component, stir to water white transparency state；
(2) after the completion of said process, aqueous phase pot opens cooling, when temperature is near 45 DEG C, adds B group raw materials, stirring is equal It is even；
(3) after the completion of said process, C group raw materials is added, are stirred；
(4) when temperature is near 35 DEG C, after continuing stirring 15 minutes, discharging, indices are determined；
(5) can be carried out after indices are qualified filling.
Preservation challenge experiment is carried out to embodiment 1-4 Essence
(1) preservation challenge result of the test is carried out to embodiment 1
(2) preservation challenge result of the test is carried out to embodiment 2
(3) preservation challenge result of the test is carried out to embodiment 3
Sample connects the time placed after bacterium Test microbes Total plate count (CFU/ML) Killing rate (%)
When 0 Bacterium 3.2×106 /
Fungi 2.8×106 /
1 day Bacterium 1.02×105 96.81
Fungi 2.35×104 99.16
7 days Bacterium 5.2×102 99.98
Fungi <10 99.99
14 days Bacterium 18 99.99
Fungi <10 99.99
28 days Bacterium <10 99.99
Fungi <10 99.99
(4) preservation challenge result of the test is carried out to embodiment 4
(5) judgment criteria：It is required that at the 7th day, bacterial inactivation rate reduction by 99.9%, fungi killing rate reduction by 90%, and And the continuous decrease in 28 days, then it is considered as and is tested by preservation challenge.
(6) result is challenged：By data above as can be seen that embodiment 1-4 is tested by preservation challenge.
Above-described is only the preferred embodiments of the present invention.It should be pointed out that the ordinary skill for this area For personnel, without departing from the principles of the present invention, some improvement and modification can also be made, this is also considered as the present invention's Protection domain.

Claims (9)

  1. A kind of 1. no added preservative used for cosmetic, it is characterised in that：Its mass percent forms：
    Methyl propanediol：6.0% -10.0%, 1,2- pentanediols：1.0% -2.0%, 1,2- hexylene glycols：0.3% -0.8%, Decoyl hydroximic acid/1,3- propane diols：0.1% -0.5%, EDETATE SODIUM：0.05%；Each component weight percent is respectively 100%.
  2. 2. one kind no added preservative used for cosmetic according to claim 1, it is characterised in that：Methyl propanediol almost without Poison, to skin and eye irritation；Its branched structure is not easy to crystallize during the course of the reaction and product is had good storage Stability.
  3. 3. one kind no added preservative used for cosmetic according to claim 1, it is characterised in that：Decoyl hydroximic acid is a kind of Organic acid, chelating agent and short chain surfactants, also therefore realize excellent antisepsis by this several different mode.
  4. 4. one kind no added preservative used for cosmetic according to claim 3, it is characterised in that：Decoyl hydroximic acid is a kind of The acid organic acid for not having ionized state to neutral whole all holdings, can at neutral ph with excellent antibacterial, bacteriostasis property For without chemical preservative formula system.
  5. 5. one kind no added preservative used for cosmetic according to claim 3, it is characterised in that：Decoyl hydroximic acid is to Fe2+ And Fe3+There is efficient selective chelation, can prevent mould from obtaining ferro element.In iron ion constrained environment, mould Therefore growth is also restricted.
  6. 6. one kind no added preservative used for cosmetic according to claim 3, it is characterised in that：Decoyl hydroximic acid short chain table Effect living is similar with ethohexadiol, and decoyl hydroximic acid also contains optimal carbon chain lengths (C8), can effectively facilitate membrane structure degraded.
  7. 7. one kind no added preservative used for cosmetic according to claim 1, it is characterised in that：Polyalcohol is micro- by destroying Biological cell membrane, vesica is formed so as to play a part of effective antibacterial.In general, carbon chain lengths are longer, fungistatic effect is better, But excitant also can be bigger therewith.This is also the reason for we want ratio between rational allocation polyalcohol, so accomplishing as far as possible In effective range, the excitant of skin will be preferably minimized.
  8. 8. one kind no added preservative used for cosmetic according to claim 1, it is characterised in that：EDETATE SODIUM is mineral matter Chelating agent, there is Synergistic antisepsis.
  9. 9. one kind no added preservative used for cosmetic according to claim 1, it is characterised in that：The protective system is except can Beyond the aqua products such as Essence, it can be also used in the different types of cosmetics such as facial mask, emulsion, cream.
CN201711222107.0A 2017-11-29 2017-11-29 A kind of no added preservative used for cosmetic Pending CN107714497A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110897913A (en) * 2019-11-28 2020-03-24 张家港美景荣化学工业有限公司 1, 3-propylene glycol-rich anti-corrosion system for cosmetics and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920612A (en) * 2012-07-02 2013-02-13 南京斯拜科生化实业有限公司 Broad-spectrum antibacterial cosmetic antiseptic and application thereof
CN106377439A (en) * 2016-10-27 2017-02-08 广州市花安堂生物科技有限公司 Anticorrosive composition without any chemically synthesized preservative and application thereof, and cosmetics prepared from anticorrosive composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920612A (en) * 2012-07-02 2013-02-13 南京斯拜科生化实业有限公司 Broad-spectrum antibacterial cosmetic antiseptic and application thereof
CN106377439A (en) * 2016-10-27 2017-02-08 广州市花安堂生物科技有限公司 Anticorrosive composition without any chemically synthesized preservative and application thereof, and cosmetics prepared from anticorrosive composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110897913A (en) * 2019-11-28 2020-03-24 张家港美景荣化学工业有限公司 1, 3-propylene glycol-rich anti-corrosion system for cosmetics and application thereof
CN110897913B (en) * 2019-11-28 2022-05-31 张家港美景荣化学工业有限公司 1, 3-propylene glycol-rich anti-corrosion system for cosmetics and application thereof

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Application publication date: 20180223

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