CN110236983A - The cleaning compositions of amphoteric ion type interfacial agent - Google Patents
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
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Abstract
The present invention provides a kind of cleaning compositions of amphoteric ion type interfacial agent comprising: an amphoteric ion type interfacial agent；One soda acid buffer solution；And water, wherein the weight percent of the amphoteric ion type interfacial agent is 1~90%, and the weight percent of the soda acid buffer solution is 0.2~20%, and the pH value of the cleaning compositions of the amphoteric ion type interfacial agent is between 3.0~6.6.The cleaning compositions of amphoteric ion type interfacial agent provided by the invention, it is controlled amphoteric ion type interfacial agent under acidic conditions by soda acid buffer solution, it is set to achieve the effect that antibacterial in cationic, and the cleaning compositions of amphoteric ion type interfacial agent of the invention, its skin irritation is much smaller than other interfacial agents, can be widely used in the cleaning anti-microbial of human body.
Description
Technical field
The present invention relates to a kind of cleaning compositions, the cleaning more particularly to a kind of amphoteric ion type interfacial agent is combined
Object.
Background technique
The outer anthropophagy mouthful of society increases now, and food sanitation and safety has become the public important class that dare not ignore and pay attention to
Topic.It is engaged in food and drink and relevant food dealer, it is often necessary to which, by both hands operation manufacture food, the cleaning of hand and health become operation
The most important work of food safety and sanitation is safeguarded in front and back, therefore is cleaned by using a variety of detergent treatment both hands, has become existing
For a part that will be faced in people's life everyday.
Related general commercially available hand cleaning agent, can achieve the purpose that antibacterial, mainly include alcohol or antibacterial agent etc.
The ingredient of organic solvent, wherein alcohol is that have that protein or ferment can be made to be denaturalized, can dissolve lipid and dehydration by it
Etc. characteristics, therefore by the Lipid dissolution of the cell membrane of microorganism or cell wall or the dehydration of microorganism can be led to.And antibacterial agent
(such as: three sodium chlorate, amine cease fragrant acids) is similarly also to reach to go out in turn by way of destroying the cell membrane and cell wall of bacterium
The effect of bacterium.
In addition, cationic sterilization method, be develop in recent years be different from the another of high-temperature sterilization and chemicals sterilization
A kind of new technology.Its sterilize mode be since the cell wall and cell membrane of bacterium are made of Phospholipids bimolecular film, and according to
The attracting principle of the physics charges of different polarity, as long as cationic germicide is added, negatively charged cell wall will be by cation
Positive charge is attracted, and promotes cell wall and the thorough deformation fracture of cell membrane, and bacterium loses breeding and survival ability and death.
However, although above-mentioned mentioned detergent has the effect of antibacterial, with irritating to human skin
It influences, in view of this, just in need provide a kind of cleaning compositions of amphoteric ion type interfacial agent, can solve above-mentioned
Problem.
Summary of the invention
In view of this, the purpose of the present invention is to provide a kind of cleaning compositions of amphoteric ion type interfacial agent, with
Commercially available detergent is compared, and is not stimulated and good anti-bacterial effect mildly relatively human skin.
In order to reach above-mentioned purpose, the invention discloses a kind of cleaning compositions of amphoteric ion type interfacial agent,
Comprising:
One amphoteric ion type interfacial agent；
One soda acid buffer solution；And
Water,
Wherein the weight percent of the amphoteric ion type interfacial agent is 1~90%, the weight of the soda acid buffer solution
Percentage is 0.2~20%, and the pH value of the cleaning compositions of the amphoteric ion type interfacial agent is between 3.0~6.6.
Further, wherein the amphoteric ion type interfacial agent be selected from by glycine betaine (Betaine) type interfacial agent,
Amine oxide (Amine oxide) type interfacial agent, ammonium metal carboxylate (Polyquaternium) type interfacial agent, imidazoles
Group composed by least one of quinoline (Imidazoline) type interfacial agent and amino acid pattern interfacial agent.
Further, wherein the composition of glycine betaine (Betaine) the type interfacial agent includes: lauryl betaine
(Lauryl Betaine), Cocoamidopropyl betaine (Cocoamidopropyl Betaine), dodecanamide propyl beet
Alkali (Lauramidopropyl Betaine), decyl betaine (Decyl betaine), alkyl betaine (Alkyl
Betaine), cocoyl-glycine betaine (Coco-betaine), cetyl betaine (Cetyl betaine), ox lipid-based betaine
(Tallow betaine), behenyl base glycine betaine (Behenyl betaine), stearyl betaine (Stearyl betaine),
It is myristyl betaine (Myristyl betaine), cocoamidoethyl betaine (Cocamidoethyl betaine), big
Soyamide propyl betaine (Soyamidopropyl betaine), oleamide propyl betaine (Oleamidopropyl
Betaine), sesame amido propyl betaine (Sesamidopropyl betaine), oat oil amido propyl betaine
(Oatamidopropyl Betaine), palm oil amido propyl betaine (Palmamidopropyl betaine), cocounut oil acyl
Amine hydroxysultaine (Cocamidopropyl hydroxysultaine) and lauryl hydroxyl sulfo betaine
(Lauryl hydroxysultaine)。
Further, wherein the composition of amine oxide (Amine oxide) the type interfacial agent includes: dodecyl oxygen
Change amine (Lauryl Dimethyl Amine Oxide), cocoamine oxide (Cocamine oxide), oleyl amine oxide
(Oleamine oxide), lauryl amine oxide (Lauramine oxide), behenyl amine oxide (Behenamine
Oxide), stearic amine oxide (Stearamine oxide), decyl amine oxide (Decylamine oxide), tallow base
Amine oxide (Tallowamine oxide), palm amine oxide (Palmitamine oxide), nutmeg amine oxide
(Myristamine oxide), trimethylamine oxide (Trimethylamine Oxide), PEG-3 distearate lauryl
Amine oxide (PEG-3 Lauramine oxide), sesame oil amido propyl amine oxide (Sesamidopropylamine
Oxide), cocamidopropyl propyl amide amine oxide (Cocamidopropylamine oxide), soybean oil amide groups propylamine oxide
(Soyamidopropylamine Oxid), oleoyl amido propylamine oxide (Oleamidopropylamine oxide), olive
Oleamide propylamine oxide (Olivamidopropylamine oxide) and cocounut oil acyl both sexes base disodium beclomethasone (Disodium
cocoamphodipropionate)。
Further, wherein the composition of ammonium metal carboxylate (Polyquaternium) the type interfacial agent includes:
Polyquaternium -39 (Polyquaternium-39), ethylenediamine disuccinic acid trisodium (Trisodium ethylenediamine
) and polyquaternium -51 (Polyquaternium-51) disuccinate.
Further, wherein the composition of imidazoline (Imidazoline) the type interfacial agent includes: cocounut oil acyl both sexes
Guanidine-acetic acid sodium (Sodium cocoamphoacetate), osmanthus acyl both sexes guanidine-acetic acid sodium (Sodium lauroamphoacetate),
Cocounut oil acyl both sexes base diethyl acid disodium (Disodium Cocoamphodiacetate) and cocounut oil acyl both sexes base sodium propionate
(Sodium Cocoamphopropionate)。
Further, wherein the composition of the amino acid pattern interfacial agent includes: acetyl group hexapeptide (Acetyl
Hexapeptide-8), avenin (Hydrolyzed Oat Protein), hydrolysis conchiolin (Hydrolyzed are hydrolyzed
Conchiolin Protein) and five cyclic polypeptides (Palmitoyl pentapeptide-4).
Further, wherein the pH value of the soda acid buffer solution is between 3.0~6.6, and the soda acid buffer solution packet
Contain: citric acid solution (Citric acid buffer), citrate buffer solution (citrate buffer), acetic acid
Buffer solution (Acetic acid buffer), phosphate buffer solution (Phosphate acid buffer) and glycine buffer
Solution (Glycine buffer).
Further, wherein the cleaning compositions have further included wax class, thickener, finish, colorant, preservative, essence
And antioxidant.
Another object of the present invention is to disclose a kind of preparation side of the cleaning compositions of amphoteric ion type interfacial agent
Method, it includes following steps:
(1) at room temperature, the amphoteric ion type interfacial agent and a weight percent of a weight percent 1-90% is added
Soda acid buffer solution than 0.2~20% is into a container, and stirring and dissolving is to form one first mixed solution；
(2) pH value for adjusting first mixed solution makes the pH value of first mixed solution between 3.0~6.6, with
Form one second mixed solution；And
(3) water is added into second mixed solution, so that the weight percent of composition is reached 100%, then persistently stirs
It mixes to being completely dissolved to get the cleaning compositions of an amphoteric ion type interfacial agent.
Effect major embodiment of the invention is:
1. it can effectively provide the effect of sterilizing cleaning；
2. the cleaning compositions of amphoteric ion type interfacial agent provided by the present invention, do not cause to hurt to human skin
Evil, belongs to the cleaning compositions of mild；
3. its manufacturing process is simple and at low cost.
Detailed description of the invention
Fig. 1 is the preparation method flow chart of the cleaning compositions of amphoteric ion type interfacial agent of the present invention；
Fig. 2 washes one's hands for 1 antibacterial of the embodiment of the present invention admires the E. coli clones analysis chart of silk；
Fig. 3 washes one's hands for 1 antibacterial of the embodiment of the present invention admires the Pseudomonas aeruginosa bacterium colony analysis chart of silk；And
Fig. 4 washes one's hands for 1 antibacterial of the embodiment of the present invention admires the Friedlander's bacillus bacterium colony analysis chart of silk.
Wherein,
S100~S300 prepares the step of cleaning compositions of amphoteric ion type interfacial agent.
Specific embodiment
The embodiments such as other features and advantages of the present invention, but this and Figure of description will be further illustrated in the following example
It is merely illustrative and use, not limitation of the present invention.
The cleaning compositions of a kind of amphoteric ion type interfacial agent provided by the invention, it is necessary to contain an amphoteric ion type
Interfacial agent；One soda acid buffer solution；And water, wherein the weight percent of the amphoteric ion type interfacial agent be 1~
90%, the weight percent of the soda acid buffer solution is 0.2~20%, and the cleaning combination of the amphoteric ion type interfacial agent
The pH value of object is between 3.0~6.6.It is directed to feature description of the invention further below.
Related amphoteric ion type interfacial agent:
Amphoteric ion type interfacial agent used in the present invention be selected from by glycine betaine (Betaine) type interfacial agent,
Amine oxide (Amine oxide) type interfacial agent, ammonium metal carboxylate (Polyquaternium) type interfacial agent, imidazoles
At least one composed group of quinoline (Imidazoline) type interfacial agent and amino acid pattern interfacial agent.
Wherein glycine betaine (Betaine) type interfacial agent can be dissolved in acid, neutral or alkalinity aqueous solution, and be had
There is the characteristic for not generating precipitating in isoelectric point, furthermore its penetration, detergency and the excellent performances such as antistatic, it also can be as emulsification
Agent and the use of softening agent.
As described above, the composition of glycine betaine (Betaine) type interfacial agent mainly can be divided into carboxylic acid group's glycine betaine, sulfo group
The three categories such as glycine betaine and phosphate ester glycine betaine comprising have: lauryl betaine (Lauryl Betaine), coconut oleoyl amine
Propyl betaine (Cocoamidopropyl Betaine), lauroylamidopropyl betaine (Lauramidopropyl
Betaine), decyl betaine (Decyl betaine), alkyl betaine (Alkyl betaine), cocoyl-glycine betaine
(Coco-betaine), cetyl betaine (Cetyl betaine), ox lipid-based betaine (Tallow betaine), behenyl
Base glycine betaine (Behenyl betaine), stearyl betaine (Stearyl betaine), myristyl betaine
(Myristyl betaine), cocoamidoethyl betaine (Cocamidoethyl betaine), soybean oil amido propyl sweet tea
Dish alkali (Soyamidopropyl betaine), oleamide propyl betaine (Oleamidopropyl betaine), sesame acyl
Amine propyl betaine (Sesamidopropyl betaine), oat oil amido propyl betaine (Oatamidopropyl
Betaine), palm oil amido propyl betaine (Palmamidopropyl betaine), cocamidopropyl propyl amide weight ratio sweet tea
Dish alkali (Cocamidopropyl hydroxysultaine) and lauryl hydroxyl sulfo betaine (Lauryl
hydroxysultaine)。
In the part of amine oxide (Amine oxide) type interfacial agent, composition includes: dodecyl amine oxide
(Lauryl Dimethyl Amine Oxide), cocoamine oxide (Cocamine oxide), oleyl amine oxide
(Oleamine oxide), lauryl amine oxide (Lauramine oxide), behenyl amine oxide (Behenamine
Oxide), stearic amine oxide (Stearamine oxide), decyl amine oxide (Decylamine oxide), tallow base
Amine oxide (Tallowamine oxide), palm amine oxide (Palmitamine oxide), nutmeg amine oxide
(Myristamine oxide), trimethylamine oxide (Trimethylamine Oxide), PEG-3 distearate lauryl
Amine oxide (PEG-3 Lauramine oxide), sesame oil amido propyl amine oxide (Sesamidopropylamine
Oxide), cocamidopropyl propyl amide amine oxide (Cocamidopropylamine oxide), soybean oil amide groups propylamine oxide
(Soyamidopropylamine Oxid), oleoyl amido propylamine oxide (Oleamidopropylamine oxide), olive
Oleamide propylamine oxide (Olivamidopropylamine oxide) and cocounut oil acyl both sexes base disodium beclomethasone (Disodium
cocoamphodipropionate)。
In addition, in the part of ammonium metal carboxylate (Polyquaternium) type interfacial agent, composition then includes
Have: polyquaternium -39 (Polyquaternium-39), ethylenediamine disuccinic acid trisodium (Trisodium
Ethylenediamine disuccinate) and polyquaternium -51 (Polyquaternium-51).
Related imidazoline (Imidazoline) type interfacial agent includes a ring and a quinquevalent nitrogen original in molecule
The structure of son.The precursor structure of imidazoline is imidazoles, and reflection molecular structure is the five-ring heterocycles comprising tertiary carbon and imine group.Tool
There is efficient, nontoxic, low irritant and has excellent biodegradation character.
And the composition of described imidazoline (Imidazoline) the type interfacial agent includes: cocoamphoacetate
Sodium (Sodium cocoamphoacetate), osmanthus acyl both sexes guanidine-acetic acid sodium (Sodium lauroamphoacetate), cocounut oil acyl
Both sexes base diethyl acid disodium (Disodium Cocoamphodiacetate) and cocounut oil acyl both sexes base sodium propionate (Sodium
Cocoamphopropionate)。
Furthermore amphoteric ion type interfacial agent above-mentioned also can be further amphoteric ion type circle of amino acid pattern series
Face activating agent, wherein the composition of the amino acid pattern interfacial agent include: acetyl group hexapeptide (Acetyl Hexapeptide-
8) avenin (Hydrolyzed Oat Protein), hydrolysis conchiolin (Hydrolyzed Conchiolin, are hydrolyzed
) and five cyclic polypeptides (Palmitoyl pentapeptide-4) Protein.
Further, the amphoteric ion type interfacial agent is the principal component of whole cleaning compositions, weight hundred
Divide and account for overall 1~90%, can be further the 5~30% of overall weight percentage, further also can be total weight
Measure the 8~20% of percentage.
Related soda acid buffer solution:
Soda acid buffer solution used in the present invention is mainly conjugate acid and base buffer solution, and it includes have: lemon acid buffering
Solution (Citric acid buffer), citrate buffer solution (citrate buffer), hac buffer (Acetic
Acid buffer), phosphate buffer solution (Phosphate acid buffer) and glycine buffer (Glycine
buffer)。
Above-mentioned soda acid buffer solution, pH value must be illustrated further below and deployed between 3.0~6.6
Concentration ratio and range when various soda acid buffer solutions.
1. citric acid solution (Citric acid buffer), solution concentration is controlled in 0.01-5 mole concentration
(mol/l), preferably suggest being 0.1 mole concentration (mol/l).Wherein citric acid solution (Citric acid buffer) is
Made of as mixed by citric acid (Citric acid) and disodium hydrogen phosphate (di sodium hydrogen phosphate),
When citric acid (Citric acid) is X=27.9~80.3%, disodium hydrogen phosphate (disodium hydrogen
It phosphate) is then (100-X) %.
According to above-mentioned, wherein disodium hydrogen phosphate (disodium hydrogen phosphate) also can be further replaced into
Sodium phosphate (sodium phosphate).
2. citrate buffer solution (citrate buffer), solution concentration are also controlled at 0.01-5 mole concentration
(mol/l), preferably suggest being 0.1 mole concentration (mol/l).Wherein citrate buffer solution (Citric buffer) be by
Made of disodium citrate (di-sodium citrate) and hydrochloric acid (HCl) are mixed, as disodium citrate (di-sodium
Citrate) be X=39.9~100% when, hydrochloric acid (HCl) then be (100-X) %, and its pH value preferably suggests be 3.0~5.0
Between.
3. hac buffer (Acetic acid buffer), solution concentration is also controlled at 0.01-5 mole concentration
(mol/l), preferably suggest being 0.1 mole concentration (mol/l).Wherein hac buffer (Acetic acid buffer) be by
Made of sodium acetate (sodium Acetic acid) and acetic acid (Acetic acid) are mixed, as sodium acetate (sodium
Acetic acid) when being X=10.9~89.3%, acetic acid (Acetic acid) is then (100-X) %, and its pH value is preferably built
View is between 3.8~5.8.
4. phosphate buffer solution (Phosphate acid buffer), solution concentration is also controlled at 0.01-5 mole
Concentration (mol/l) preferably suggests being 1/15 mole concentration (mol/l).Wherein phosphate buffer solution (Phosphate acid
It buffer is) by potassium dihydrogen phosphate (potassium dihydrogen phosphate acid) and disodium hydrogen phosphate (di-
Sodium dihydrogen phosphate acid) it is mixed made of, as potassium dihydrogen phosphate (potassium
Dihydrogen phosphate acid) be X=65.3~99.2% when, disodium hydrogen phosphate (di-sodium dihydrogen
Phosphate acid) it is then (100-X) %, and its pH value preferably suggests being between 5.0~6.6.
5. glycine buffer (Glycine buffer), solution concentration are also controlled at 0.01-5 mole concentration
(mol/l), preferably suggest being 0.1 mole concentration (mol/l).Wherein glycine buffer (Glycine buffer) is by sweet
Made of propylhomoserin (glycine) and sodium chloride (NaCl) are mixed, when glycine (glycine) is X=81~90.3%, chlorine
Changing sodium (NaCl) is then (100-X) %, and its pH value preferably suggests being between 3.0~5.0.
Further, the weight percent of the soda acid buffer solution accounts for overall 0.2~20%, further can be total
The 0.2~15% of body weight percentage further also can be the 0.2~10% of overall weight percentage.
In summary, soda acid buffer solution provided by the present invention is primarily used to adjust whole cleaning compositions
PH value enables the cleaning compositions of the amphoteric ion type interfacial agent to be under acid environment, provide cation with
The effect of reaching antibacterial, and can in response to cleaning supplies project and change its acid size, such as: the pH suitable for human body
Value will be adjusted to acidity on the weak side, between pH value about 5.0~6.6；If being used for the detergent articles of house, pH value then may be used
It falls between 3.0~6.6.
Further, the cleaning compositions of amphoteric ion type interfacial agent provided by the present invention more may include have it is various
Wax class, thickener and finish, can mainly arrange in pairs or groups in turn use, such as frost of washing one's hands in response to the presentation of cleaning products dosage form.
Furthermore the cleaning compositions of the amphoteric ion type interfacial agent also can further include colorant, prevent
Rotten agent, essence and antioxidant.
Another object of the present invention additionally provides a kind of preparation side of the cleaning compositions of amphoteric ion type interfacial agent
Method, specific as follows:
Referring to Fig. 1, Fig. 1 is the preparation method process of the cleaning compositions of amphoteric ion type interfacial agent of the present invention
Figure.It carries out step 1 (S100) first: at room temperature, the amphoteric ion type interfacial agent of a weight percent 1-90% is added
And one weight percent 0.2~20% soda acid buffer solution into a container, stirring and dissolving is to form one first mixed solution；
Then step 2 (S200): the pH value of first mixed solution is adjusted, makes the pH value of first mixed solution between 3.0~6.6
Between, to form one second mixed solution；And step 3 (S300): water is added into second mixed solution, makes composition
Weight percent reach 100%, then continue stirring until the cleaning being completely dissolved to get an amphoteric ion type interfacial agent
Composition.
It is by using the citric acid in the aforementioned soda acid buffer solution referred to wherein in step 2 (S200)
(Citric acid), hydrochloric acid (HCl), acetic acid (Acetic acid), potassium dihydrogen phosphate (potassium dihydrogen
Phosphate acid) and glycine (glycine) any one of them acid as acid regulator, and the regulator of alkalinity
It is then based on sodium hydroxide (NaOH).
In summary, the present invention controls the pH value of amphoteric ion type interfacial agent in acid using soda acid buffer solution
Property condition makes amphoteric ion type interfacial agent be maintained in cationic kenel under acidic environment, it is made to have cationic
The antibacterial ability of interfacial agent, since the skin irritation of amphoteric ion type interfacial agent is living much smaller than cationic interface
Property agent and other chemical antibacterial agents or fungicide, therefore be very suitable to using in human body clean antibacterial application.
Embodiment 1- antibacterial, which is washed one's hands, admires the antibacterial test of silk
Fig. 2~Fig. 4 is please referred to, Fig. 2 washes one's hands for 1 antibacterial of the embodiment of the present invention admires E. coli clones analysis chart, Fig. 3 of silk
It washes one's hands the Pseudomonas aeruginosa bacterium colony analysis chart for admiring silk for 1 antibacterial of the embodiment of the present invention and Fig. 4 is that 1 antibacterial of the embodiment of the present invention is washed one's hands and admired
The Klebsiella bacterium colony analysis chart of silk.The results show that antibacterial wash one's hands admire silk respectively with Escherichia coli, Pseudomonas aeruginosa and Cray primary
After Salmonella bacterium solution acts on 10 seconds, all the bacterium colony without Escherichia coli is grown on culture medium, illustrates the antibacterial of the embodiment of the present invention 1
It washes one's hands and admires silk and have the effect of antibacterial, wherein the left side culture medium being shown in Fig. 2~Fig. 4 is control group, and the right culture medium
For experimental group (antibacterial, which is washed one's hands, admires silk).
The method of following further clarification test:
Test strain: Escherichia coli (Escherichia coli, ATCC 8739), Pseudomonas aeruginosa and Klebsiella
Action condition: 25 ± 2 DEG C；Effect 10 seconds.
Condition of culture: 35 ± 2 DEG C；Culture 48 hours.
Test grouping: control group: 0.85% sterile physiological saline solution；Experimental group: antibacterial, which is washed one's hands, admires silk.
The wash one's hands antibacterial test of curtain silk of 1 antibacterial of the embodiment of the present invention is mode according to JIS Z2801:2010, first
It is about first first 107CFU/mL by bacterium amount configuration concentration to desired bacterium number, the species suspension of 0.1mL is taken to add to 10mL control group
And experimental group, it, in 25 ± 2 DEG C, will then be acted on 10 seconds, and with 9mL aseptic experiment water after control group and experimental group inoculation bacterium solution
Control group and experimental group are subjected to 10 times of serial dilutions respectively, are finally inoculated in after serial dilution on culture medium appropriate, it will
Culture medium is placed under environment described in condition of culture and cultivates, and observes its upgrowth situation respectively and records clump count.Related antibacterial energy
The calculation formula of power, as follows:
Antibiotic rate (%)=(control group remains bacterium amount-experimental group and remains bacterium amount)/control group remains bacterium amount * 100%
Then table one is please referred to, table one is that antibacterial is washed one's hands the antibacterial effect analysis after the effect of Mu Siyu different strain, as a result
Display antibacterial is washed one's hands after Mu Siyu bacterium solution acts on 10 seconds, and the antibiotic rate to Escherichia coli, Pseudomonas aeruginosa and citric acid is >
99.99%.
Table one
Further, also antibacterial is washed one's hands admire silk respectively with Methicillin-resistant Staphylococcus color staphylococcus and Salmonella enteritidis bacterium solution
Effect, to carry out antibacterial tests, as a result, it has been found that antibacterial, which is washed one's hands, admires silk for salmonella with antibacterial effect, and for drug resistance
The antibacterial ability of staphylococcus aureus, then be it is invalid (as shown in Table 2), this result illustrates that antibacterial is washed one's hands and admires the antibacterial of silk
The possible major embodiment of effect is in the part of prolapse of uterus.
Table two
As described above, wherein washing one's hands in relation to 1 antibacterial of the embodiment of the present invention admires the component ratio of silk, table three is please referred to.
Table three
| Ingredient (Chinese)/English | Ratio wt% |
| Cocoamidopropyl betaine (Cocoamidopropyl Betaine) | 1-70% |
| Citric acid (Citric acid) | 1-10% |
| Sodium phosphate (sodium phosphate) | 1-10% |
| Water | Remaining amount |
In conclusion the foregoing is merely presently preferred embodiments of the present invention, not thereby limits patent of the invention and protect
Shield range, therefore description of the invention and the made equivalence changes of attached drawing etc. such as, should all be included in protection scope of the present invention.
Claims (10)
1. a kind of cleaning compositions of amphoteric ion type interfacial agent characterized by comprising
One amphoteric ion type interfacial agent；
One soda acid buffer solution；And
Water,
Wherein the weight percent of the amphoteric ion type interfacial agent is 1~90%, the weight percent of the soda acid buffer solution
Than being 0.2~20%, the pH value of the cleaning compositions of the amphoteric ion type interfacial agent is between 3.0~6.6.
2. the cleaning compositions of amphoteric ion type interfacial agent as described in claim 1, which is characterized in that the amphoteric ion
Type interfacial agent is selected from living by betaine type interfacial agent, amine oxide type interfacial agent, ammonium Carboxylate-type interface
Group composed by least one of property agent, imidazoline type interfacial agent and amino acid pattern interfacial agent.
3. the cleaning compositions of amphoteric ion type interfacial agent as claimed in claim 2, which is characterized in that the betaine type
The composition of interfacial agent includes: lauryl betaine, Cocoamidopropyl betaine, lauroylamidopropyl betaine, the last of the ten Heavenly stems
Base glycine betaine, alkyl betaine, cocoyl-glycine betaine, cetyl betaine, ox lipid-based betaine, behenyl base glycine betaine, tristearin
Base glycine betaine, myristyl betaine, cocoamidoethyl betaine, soybean oil amido propyl betaine, oleamide propyl sweet tea
Dish alkali, sesame amido propyl betaine, oat oil amido propyl betaine, palm oil amido propyl betaine, coconut oleoyl amine third
Base hydroxyl sulfo betaine and lauryl hydroxyl sulfo betaine.
4. the cleaning compositions of amphoteric ion type interfacial agent as claimed in claim 2, which is characterized in that the amine oxide type
The composition of interfacial agent includes: dodecyl amine oxide, cocoamine oxide, oleyl amine oxide, lauryl amine oxide,
Behenyl amine oxide, stearic amine oxide, decyl amine oxide, tallow base amine oxide, palm amine oxide, nutmeg amine
Oxide, trimethylamine oxide, PEG-3 distearate lauryl amine oxide, sesame oil amido propyl amine oxide, cocounut oil
Amido propyl amine oxide, soybean oil amide groups propylamine oxide, oleoyl amido propylamine oxide, the oxidation of olivamidopropyl propylamine
Object and cocounut oil acyl both sexes base disodium beclomethasone.
5. the cleaning compositions of amphoteric ion type interfacial agent as claimed in claim 2, which is characterized in that the ammonium carboxylic acid
The composition of salt type interfacial agent includes: polyquaternium -39, ethylenediamine disuccinic acid trisodium and polyquaternium -51.
6. the cleaning compositions of amphoteric ion type interfacial agent as claimed in claim 2, which is characterized in that the imidazoline type
The composition of interfacial agent includes: sodium cocoamphoacetate, osmanthus acyl both sexes guanidine-acetic acid sodium, cocounut oil acyl both sexes base oxalic acid
Disodium and cocounut oil acyl both sexes base sodium propionate.
7. the cleaning compositions of amphoteric ion type interfacial agent as claimed in claim 2, which is characterized in that the amino acid pattern
The composition of interfacial agent includes: acetyl group hexapeptide, hydrolysis avenin, hydrolysis conchiolin and five cyclic polypeptides.
8. the cleaning compositions of amphoteric ion type interfacial agent as described in claim 1, which is characterized in that soda acid buffering
The pH value of solution is between 3.0~6.6, and the soda acid buffer solution includes: citric acid solution, Citrate buffer
Solution, hac buffer, phosphate buffer solution and glycine buffer.
9. the cleaning compositions of amphoteric ion type interfacial agent as described in claim 1, which is characterized in that cleaning combination
Object has further included wax class, thickener, finish, colorant, preservative, essence and antioxidant.
10. a kind of method for the cleaning compositions for preparing amphoteric ion type interfacial agent as described in claim 1, feature
It is comprising the steps of:
(1) at room temperature, the amphoteric ion type interfacial agent and a weight percent 0.2 of a weight percent 1-90% is added
~20% soda acid buffer solution is into a container, and stirring and dissolving is to form one first mixed solution；
(2) pH value for adjusting first mixed solution makes the pH value of first mixed solution between 3.0~6.6, to be formed
One second mixed solution；And
(3) water is added into second mixed solution, so that the weight percent of composition is reached 100%, then continues stirring until
It is completely dissolved to get the cleaning compositions of an amphoteric ion type interfacial agent.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810196040.6A CN110236983A (en) | 2018-03-09 | 2018-03-09 | The cleaning compositions of amphoteric ion type interfacial agent |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810196040.6A CN110236983A (en) | 2018-03-09 | 2018-03-09 | The cleaning compositions of amphoteric ion type interfacial agent |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023004511A1 (en) * | 2021-07-30 | 2023-02-02 | Katal Energy Inc. | Surfactant compositions, emulsions including surfactant compositions, and methods of preparing same |
Citations (3)
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|---|---|---|---|---|
| US6805874B1 (en) * | 2002-12-03 | 2004-10-19 | Permamed Ag | Method and skin cleansing compositions for dermatological basic treatment |
| US20110319308A1 (en) * | 2010-06-24 | 2011-12-29 | Euen Thomas Graham Ekman Gunn | Low-irritating, clear cleansing compositions with relatively low ph |
| CN106901993A (en) * | 2015-12-22 | 2017-06-30 | 江南大学 | Mild antibiotic skincare hand cleanser is formulated |
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2018
- 2018-03-09 CN CN201810196040.6A patent/CN110236983A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6805874B1 (en) * | 2002-12-03 | 2004-10-19 | Permamed Ag | Method and skin cleansing compositions for dermatological basic treatment |
| US20110319308A1 (en) * | 2010-06-24 | 2011-12-29 | Euen Thomas Graham Ekman Gunn | Low-irritating, clear cleansing compositions with relatively low ph |
| CN106901993A (en) * | 2015-12-22 | 2017-06-30 | 江南大学 | Mild antibiotic skincare hand cleanser is formulated |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023004511A1 (en) * | 2021-07-30 | 2023-02-02 | Katal Energy Inc. | Surfactant compositions, emulsions including surfactant compositions, and methods of preparing same |
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