CN110227048A - Efficient anti-dandruff and itching-relieving shampoo, hair lotion and hair film - Google Patents
Efficient anti-dandruff and itching-relieving shampoo, hair lotion and hair film Download PDFInfo
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Abstract
The invention discloses efficient anti-dandruff and itching-relieving shampoo, hair lotion and hair film, the shampoo, hair lotion and hair film contain the anti-dandruff and itching-relieving composition that can inhibit chlosma fast-growth and reduce its drug resistance.Mass fraction of the component and each component of the anti-dandruff and itching-relieving composition in shampoo, hair lotion or hair film are as follows: new health azoles 0.1~1%, plant extracts 0.5~10%, keratin 0.1~2%；The plant extracts is made of coptis extract, houttuynia extract, Cacumen Platycladi extract.Shampoo, hair lotion and hair film of the present invention not only have the function of efficient anti-dandruff and itching-relieving, but also do not influence the flexibility, glossiness and salubrious sense of hair after use.
Description
Technical field
The invention belongs to hair-washing hair-care articles fields, in particular to the shampoo of anti-dandruff and itching-relieving function, hair lotion and
Hair film.
Background technique
Everybody is intended to possess health, beautiful hair, but dandruff occur in many people, and very cause scalp itch etc. is asked
Topic.In order to solve this problem, have many patent applications to generate.For example, CN 200910094201.1 is disclosed, one kind is antipruritic to be gone
The Chinese medicine shampoo of bits, CN 201010190519.3 disclose antidandruff and antipruritic shampoo, and CN 201410822885.3 is disclosed
A kind of compound dandruff control shampoo containing of HD and ZPT and preparation method thereof, CN 201710548938.0 discloses a kind of desquamation compositions
And dandruff control shampoo containing.Although above-mentioned technical proposal have effects that anti-dandruff and itching-relieving it is certain, or there are anti-dandruff and itching-relieving effects not
Stablize, or exists and increase the problems such as developing drug resistance using the time.Therefore, further types of anti-dandruff and itching-relieving hair washing shield is developed
Hair care product is just able to satisfy the needs of people.
Summary of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide efficient anti-dandruff and itching-relieving shampoo, hair lotion and hairs
Film to realize stable anti-dandruff and itching-relieving and reduce drug resistance, and does not influence the flexibility and glossiness of hair.
Existing research shows that chlosma is the principal element for causing dandruff to generate with scalp itch, reason is
There is chlosma thermophilic lipid to stay in some fat digested using the fatty material secreted in people's scalp hair follicles as food
On scalp, becomes and cause the stimulus of dandruff (see " status and prospectives of plant anti-dandruff and itching-relieving agent ", household chemicals section
It learns, the 2nd phase of volume 34,2 months 2011).
Technical solution of the present invention: for causing dandruff to generate and the principal element of scalp itch, in shampoo, hair care
The anti-dandruff and itching-relieving composition that can inhibit chlosma fast-growth and reduce its drug resistance is added in liquid or hair film.It is described it is anti-dandruff only
Itch the mass fraction in shampoo, hair lotion or hair film of component and each component of composition are as follows: new health azoles (chemical name two
Chlorphenyl imidazoles dioxolane) 0.1~1%, plant extracts 0.5~10%, keratin 0.1~2%；The plant extracts
It is made of coptis extract, houttuynia extract and Cacumen Platycladi extract, coptis extract, houttuynia extract, cacumen biotae mention
The mass ratio for taking object is 1:1:1.
Plant extracts of the present invention the preparation method is as follows:
1, the preparation method of coptis extract
By the coptis and pure water 1:(10~12 in mass ratio) it is placed in refluxing reactor, it is heated to boiling and flow back at least 30
Minute, it then cools to room temperature and filters, gained filtrate is stored stand-by；By gained filter residue and pure water 1:(10 in mass ratio
~12) it is placed in refluxing reactor, repeats aforesaid operations twice；The filtrate of refluxing extraction three times is merged, rotary evaporation is used
Device evaporation and concentration filtrate arrives coptis extract to not flowing.
2, the preparation method of houttuynia extract
By cordate houttuynia and pure water 1:(10~12 in mass ratio) it is placed in refluxing reactor, it is heated to boiling and flow back at least
It 30 minutes, then cools to room temperature and filters, gained filtrate is stored stand-by；By gained filter residue and pure water in mass ratio 1:
(10~12) are placed in refluxing reactor, repeat aforesaid operations twice；The filtrate of refluxing extraction three times is merged, is steamed using rotation
Hair device evaporation and concentration filtrate arrives houttuynia extract to not flowing.
3, the preparation method of Cacumen Platycladi extract
By cacumen biotae and pure water 1:(10~12 in mass ratio) it is placed in refluxing reactor, it is heated to boiling and flow back at least
It 30 minutes, then cools to room temperature and filters, gained filtrate is stored stand-by；By gained filter residue and pure water in mass ratio 1:
(10~12) are placed in refluxing reactor, repeat aforesaid operations twice；The filtrate of refluxing extraction three times is merged, is steamed using rotation
Hair device evaporation and concentration filtrate arrives Cacumen Platycladi extract to not flowing.
4, it mixes
It is in mass ratio that 1:1:1 is measured and is uniformly mixed by coptis extract, houttuynia extract and Cacumen Platycladi extract,
Obtain plant extracts.
Efficient anti-dandruff and itching-relieving shampoo of the present invention, main composed of the following components, the mass fraction of each component is as follows.
The pure water is deionized water or distilled water.
In above-mentioned efficient anti-dandruff and itching-relieving shampoo, the surfactant is laureth ammonium sulfate, lauryl sulfate
Ammonium, laureth sodium sulfovinate, laureth carboxylic acid sodium, sodium lauroyl sarcosine, lauroyl glycine potassium, laruyl alcohol
At least two in sodium sulfovinate, laureth sulfosuccinate disodium；The submissive conditioner is polydimethylsiloxanes
The double propyl dimethyl silicone polymer of alkane, dimethiconol, ammonia-terminated polydimethylsiloxane, amino, Polyquaternium-10,
Polyquaternium -7, polyquaternium -47, PEG-7 glyceryl cocoate, guar hydroxypropyltrimonium chloride, hydroxypropyl melon
Glue hydroxypropyl-trimethyl ammonium chloride, polyethylene glycol -14M, at least two in polyethylene glycol -7M；The acid-base modifier is lemon
At least one of lemon acid, lactic acid, sodium lactate, triethanolamine, sodium citrate, EDTA (ethylenediamine tetra-acetic acid) and its sodium salt；Institute
Stating thickener is cocounut oil alkanol amides, coconut oleoyl amine DEA, coconut oleoyl amine MEA, coconut oleoyl amine methyl MEA, coconut oleoyl amine
MIPA, Cocoamidopropyl betaine, lauryl betaine, lauryl hydroxyl sulphur glycine betaine, lauryl glucoside, lauric acid
Ester, lauryl alcohol lactate, Sodium Lauroamphoacetate, cetostearyl alcohol, cetanol, xanthan gum, carbomer and polyacrylic acid
In at least two.
Efficient anti-dandruff and itching-relieving hair lotion of the present invention, main composed of the following components, the mass fraction of each component is as follows.
The pure water is deionized water or distilled water.
In above-mentioned efficient anti-dandruff and itching-relieving hair lotion, the hair conditioner is behenyl base trimethyl ammonium chloride, behenyl base three
Methyl ammonium sulfate, cetrimonium chloride, dimethyl silicone polymer, ring five dimethyl silicone polymer, gathers stearyl trimethyl ammonium chloride
Dimethyl silica alkanol, aminopropyl dimethyl silicone polymer, ammonia-terminated polydimethylsiloxane, Polyquaternium-10, polyquaternium-
7, guar hydroxypropyltrimonium chloride, polyethylene glycol -14M, polyethylene glycol -7M, at least two in polyethylene glycol -90M；
The acid-base modifier is at least one in citric acid, lactic acid, glutamic acid, phosphoric acid, EDTA (ethylenediamine tetra-acetic acid) and its sodium salt
Kind；The thickener is cetanol, cetostearyl alcohol, docosyl alcohol, ceteareth -25, stearine, polyquaternary amine
Salt -37, ceteareth -20, xanthan gum, acrylate copolymer, hydroxyethyl cellulose, in hydroxypropyl methyl cellulose
It is at least one.
Efficient anti-dandruff and itching-relieving hair film of the present invention, main composed of the following components, the mass fraction of each component is as follows.
The pure water is deionized water or distilled water.
In above-mentioned efficient anti-dandruff and itching-relieving hair film, the grease is dormant oil, isoparaffin, avocado oil, jojoba oil, nutmeg
Isopropyl propionate, isopropyl palmitate, Nexbase 2004, dimethyl silicone polymer, ring five dimethyl silicone polymer, poly dimethyl silicon
At least one of oxygen alkanol, aminopropyl dimethyl silicone polymer, ammonia-terminated polydimethylsiloxane；The hair conditioner is mountain
Yu base trimethyl ammonium chloride, behenyl base trimethyl ammonium sulfate, stearyl trimethyl ammonium chloride, cetrimonium chloride, distearyl two
Ammonio methacrylate, Polyquaternium-10, polyquaternium -7, guar hydroxypropyltrimonium chloride, polyethylene glycol -14M, poly- second
At least two in glycol -7M, polyethylene glycol -90M；The thickener is that cetanol, cetostearyl alcohol, docosyl alcohol, spermaceti are hard
Lipidol polyethers -25, stearine, polyquaternium -37, ceteareth -20, xanthan gum, acrylate copolymer, hydroxyl
At least one of ethyl cellulose, hydroxypropyl methyl cellulose.
Efficient anti-dandruff and itching-relieving shampoo, hair lotion or hair film of the present invention, further include essence or/and preservative, described
The mass fraction of essence is 0.1%~1%, and the mass fraction of the preservative is 0.05%~0.1%, and preservative can be first
The mixed solution that base isothiazolinone solution or methylchloroisothiazandnone and methylisothiazolinone 3:1 in mass ratio are formed.
The preparation method of above-mentioned shampoo: the 75~85% of pure water inventory are added in reactor, and it is living to add surface
Property agent, submissive conditioner, acid-base modifier and thickener, under stiring in normal heating to 60~80 DEG C and the temperature protect
Temperature obtains each component and is completely dissolved or the first evenly dispersed mixed liquor；The propylene glycol of 2~3 times of new health azoles and its quality is existed
It is heated to 75~80 DEG C under stirring and obtains new health azoles solution；60~80 DEG C of the first mixed liquor is added in new health azoles solution and is mixed
Uniformly obtain the second mixed liquor；Second mixed liquor is cooled to 45 DEG C, sequentially add keratin, plant extracts, essence (if
Have this component), preservative (if having this component) and remaining pure water, and continue stirring to each component and be uniformly mixed, it is then cold
But efficient anti-dandruff and itching-relieving shampoo is obtained to 40 DEG C or less.
The preparation method of above-mentioned hair lotion: pure water is added in reactor, hair conditioner, acid-base modifier are added
And thickener obtains each component and is completely dissolved or uniformly under stiring in normal heating to 60~80 DEG C and in the temperature
First mixed liquor of dispersion；The propylene glycol of 2~3 times of new health azoles and its quality is heated to 75~80 DEG C under stiring and obtains new health
Azoles solution；New health azoles solution is added 60~80 DEG C of the first mixed liquor and is uniformly mixed and obtains the second mixed liquor；Second is mixed
It closes liquid and is cooled to 45 DEG C, sequentially add keratin, plant extracts, essence (if having this component) and preservative (if there is this group
Point), and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains efficient anti-dandruff and itching-relieving hair lotion.
The preparation method of above-mentioned hair film: grease is added in oily phase pot, under stiring in normal heating to 60~80 DEG C；
Pure water is added in water phase pot, then hair conditioner and thickener are added into water phase pot, under stiring in normal heating
To 60~80 DEG C, water phase mixed liquor is obtained after each component dissolves and is pumped into emulsion pot, then will warm up 60~80
DEG C grease be pumped into emulsion pot, and the Temperature Vacuum emulsifying for making the material in emulsion pot maintain 60~80 DEG C is at least
10 minutes, obtain the first mixing paste；The propylene glycol of 2~3 times of new health azoles and its quality is heated to 75~80 DEG C under stiring
Obtain new health azoles solution；New health azoles solution is added 60~80 DEG C of the first mixing paste and is uniformly mixed and obtains the second compound
Second mixing paste is cooled to 45 DEG C by body, is sequentially added keratin, plant extracts, essence (if having this component) and is prevented
Rotten agent (if having this component), and continue stirring to each component and be uniformly mixed, be subsequently cooled to 40 DEG C or less obtain it is efficient anti-dandruff
Antipruritic hair film.
Compared with prior art, the invention has the following advantages:
1, there is the component of anti-dandruff and itching-relieving composition contained by shampoo of the present invention, hair lotion or hair film collaboration to make
With can effectively inhibit the growth (see embodiment 17) of chlosma, thus the shampoo containing the composition, hair lotion or hair film
Skin of head surface microenvironment can be changed, achieve the purpose that anti-dandruff and itching-relieving (see embodiment 20).Because chlosma is mainly grown
In keratoderma, the aggravation of the speed of growth destroys skin of head surface microenvironment, skin of head surface is caused spot mound occur
Rash and the desquamation of skin are itched and dandruff to generate head.The growth for inhibiting chlosma, can inhibit generation and the head of dandruff
Itch.
2, anti-dandruff and itching-relieving composition contained by shampoo of the present invention, hair lotion or hair film is due between its each component
Synergistic effect, can effectively inhibit chlosma drug resistance caused by one-component substance (see embodiment 18)；In addition, anti-dandruff and itching-relieving
Keratin in composition can repair skin of head cuticula, reduce chlosma in the attachment and growth of keratoderma.
3, efficient anti-dandruff and itching-relieving composition contained by shampoo of the present invention, hair lotion or hair film has centainly anti-inflammatory
Effect, thus the sensitizations lesion (see embodiment 19) such as can be reduced the redness of scalp, itch.
4, shampoo of the present invention, hair lotion or hair film not only have the function of efficient anti-dandruff and itching-relieving, but also use back
All good (see embodiments 21,22,23) such as flexibility, glossiness, the salubrious senses of hair.
Specific embodiment
Below by embodiment to anti-dandruff and itching-relieving composition of the present invention and efficient anti-dandruff and itching-relieving shampoo, hair lotion or
Hair film is described further.
In following embodiment, in addition to plant extracts, other components are commercially available in market.Methylisothiazolinone
The mass concentration of methylisothiazolinone is 9.5% in solution, and methylchloroisothiazandnone and methylisothiazolinone press quality
The total mass concentration of methylchloroisothiazandnone and methylisothiazolinone is 1.5% in the mixed solution formed than 3:1.
1 prepared plant extracts of embodiment
(1) preparation of coptis extract
The coptis (commercially available) 1Kg is placed in refluxing reactor, then 10Kg deionized water is added into refluxing reactor, heating
It to boiling and flowing back 30 minutes, then cools to room temperature and filters, gained first-time filtrate is stored stand-by；By filter residue of gained with
Deionized water 1:10 in mass ratio is placed in refluxing reactor, is heated to boiling and flowing back 30 minutes, is then cooled to room temperature and mistake
Filter, obtains secondary filtrate and secondary filter residue；The storage of secondary filtrate is stand-by, secondary filter residue and deionized water 1:10 in mass ratio are set
In refluxing reactor, it is heated to boiling and flowing back 30 minutes, then cools to room temperature and filter, obtain filtrate three times；It will once filter
Liquid, secondary filtrate and filtrate merging three times arrive coptis extract to not flowing using rotary evaporator evaporation and concentration filtrate
About 0.3kg；
(2) preparation of houttuynia extract
Cordate houttuynia (commercially available) 1Kg is placed in refluxing reactor, then 10Kg deionized water is added into refluxing reactor, is added
Heat is then cooled to room temperature and is filtered to boiling and flowing back 30 minutes, gained first-time filtrate is stored stand-by；By filter residue of gained
It is placed in refluxing reactor with deionized water 1:10 in mass ratio, is heated to boiling and flowing back 30 minutes, then cool to room temperature simultaneously
Filtering, obtains secondary filtrate and secondary filter residue；The storage of secondary filtrate is stand-by, by secondary filter residue and deionized water 1:10 in mass ratio
It is placed in refluxing reactor, is heated to boiling and flowing back 30 minutes, then cools to room temperature and filter, obtain filtrate three times；It will be primary
Filtrate, secondary filtrate and filtrate merges three times, are concentrated by evaporation filtrate using rotary evaporator and are mentioned to get to cordate houttuynia to not flowing
Take object about 0.3kg；
(3) preparation of Cacumen Platycladi extract
Cacumen biotae (commercially available) 1Kg is placed in refluxing reactor, then 10Kg deionized water is added into refluxing reactor, is added
Heat is then cooled to room temperature and is filtered to boiling and flowing back 30 minutes, gained first-time filtrate is stored stand-by；By filter residue of gained
It is placed in refluxing reactor with deionized water 1:10 in mass ratio, is heated to boiling and flowing back 30 minutes, then cool to room temperature simultaneously
Filtering, obtains secondary filtrate and secondary filter residue；The storage of secondary filtrate is stand-by, by secondary filter residue and deionized water 1:10 in mass ratio
It is placed in refluxing reactor, is heated to boiling and flowing back 30 minutes, then cools to room temperature and filter, obtain filtrate three times；It will be primary
Filtrate, secondary filtrate and filtrate merges three times, are concentrated by evaporation filtrate using rotary evaporator and are mentioned to get to cacumen biotae to not flowing
Take object about 0.3kg；
(4) it mixes
It is in mass ratio that 1:1:1 is measured and is uniformly mixed by coptis extract, houttuynia extract and Cacumen Platycladi extract,
Obtain plant extracts about 0.9kg.
Repeatable aforesaid operations, prepare the desired amount of plant extracts.
Plant extracts used in the following embodiment is the plant extracts of 1 the method for embodiment preparation.
Embodiment 2~6 is the preparation of shampoo.
Embodiment 2
In the present embodiment, the component of shampoo and the content of each component are as follows:
Preparation method: according to above-mentioned formula, surfactant, submissive conditioner, acid-base modifier, thickener are added to
In reactor equipped with 60Kg deionized water, each component is obtained to 60 DEG C and in the temperature in normal heating under stiring
It is completely dissolved or evenly dispersed first mixed liquor；The propylene glycol of 2 times of new health azoles and its quality is heated to 75 DEG C under stiring to obtain
To new health azoles solution；New health azoles solution is added 60 DEG C of the first mixed liquor and is uniformly mixed and obtains the second mixed liquor；By second
Mixed liquor is cooled to 45 DEG C, sequentially adds keratin, plant extracts, adds remaining 11.2Kg deionized water, and after
Continuous stirring to each component is uniformly mixed, and is subsequently cooled to 40 DEG C or less and is obtained efficient anti-dandruff and itching-relieving shampoo.
Embodiment 3
In the present embodiment, the component of shampoo and the content of each component are as follows:
Preparation method: according to above-mentioned formula, surfactant, submissive conditioner, acid-base modifier, thickener are added to
In reactor equipped with 60Kg distilled water, it is complete to obtain each component to 70 DEG C and in the temperature in normal heating under stiring
Fully dissolved or evenly dispersed first mixed liquor；The propylene glycol of 2.5 times of new health azoles and its quality is heated to 80 DEG C under stiring to obtain
To new health azoles solution；New health azoles solution is added 70 DEG C of the first mixed liquor and is uniformly mixed and obtains the second mixed liquor；By second
Mixed liquor is cooled to 45 DEG C, sequentially adds keratin, plant extracts, essence, adds remaining 14.35Kg distilled water,
And continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains efficient anti-dandruff and itching-relieving shampoo.
Embodiment 4
In the present embodiment, the component of shampoo and the content of each component are as follows:
Preparation method: according to above-mentioned formula, surfactant, submissive conditioner, acid-base modifier, thickener are added to
In reactor equipped with 60Kg deionized water, each component is obtained to 80 DEG C and in the temperature in normal heating under stiring
It is completely dissolved or evenly dispersed first mixed liquor；The propylene glycol of 3 times of new health azoles and its quality is heated to 80 DEG C under stiring to obtain
To new health azoles solution；New health azoles solution is added 80 DEG C of the first mixed liquor and is uniformly mixed and obtains the second mixed liquor；By second
Mixed liquor is cooled to 45 DEG C, sequentially adds keratin, plant extracts, adds remaining 16.0Kg deionized water, and after
Continuous stirring to each component is uniformly mixed, and is subsequently cooled to 40 DEG C or less and is obtained efficient anti-dandruff and itching-relieving shampoo.
Embodiment 5
In the present embodiment, the component of shampoo and the content of each component are as follows:
Preparation method: according to above-mentioned formula, surfactant, submissive conditioner, acid-base modifier, thickener are added to
In reactor equipped with 60Kg deionized water, each component is obtained to 75 DEG C and in the temperature in normal heating under stiring
It is completely dissolved or evenly dispersed first mixed liquor；The propylene glycol of 3 times of new health azoles and its quality is heated to 75 DEG C under stiring to obtain
To new health azoles solution；New health azoles solution is added 75 DEG C of the first mixed liquor and is uniformly mixed and obtains the second mixed liquor；By second
Mixed liquor is cooled to 45 DEG C, sequentially adds keratin, plant extracts, preservative, adds remaining 16.4Kg deionization
Water, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains efficient anti-dandruff and itching-relieving shampoo.
Embodiment 6
In the present embodiment, the component of shampoo and the content of each component are as follows:
Preparation method: according to above-mentioned formula, surfactant, submissive conditioner, acid-base modifier, thickener are added to
In reactor equipped with 60Kg deionized water, each component is obtained to 65 DEG C and in the temperature in normal heating under stiring
It is completely dissolved or evenly dispersed first mixed liquor；The propylene glycol of 2.5 times of new health azoles and its quality is heated to 75 DEG C under stiring
Obtain new health azoles solution；New health azoles solution is added 65 DEG C of the first mixed liquor and is uniformly mixed and obtains the second mixed liquor；By
Two mixed liquors are cooled to 45 DEG C, sequentially add keratin, plant extracts, add remaining 16.5Kg deionized water, and
Continue stirring to each component to be uniformly mixed, is subsequently cooled to 40 DEG C or less and obtains efficient anti-dandruff and itching-relieving shampoo.
Embodiment 7~11 is the preparation of hair lotion.
Embodiment 7
In the present embodiment, the component of hair lotion and the content of each component are as follows:
Preparation method: hair conditioner, acid-base modifier, thickener are added to the reaction equipped with 84.2Kg deionized water
In device, under stiring in normal heating to 60 DEG C and in the temperature, obtains each component and be completely dissolved or evenly dispersed
One mixed liquor；The propylene glycol of 3 times of new health azoles and its quality is heated to 75 DEG C under stiring and obtains new health azoles solution；By new health azoles
Solution, which is added 60 DEG C of the first mixed liquor and is uniformly mixed, obtains the second mixed liquor；Second mixed liquor is cooled to 45 DEG C, then according to
Secondary addition keratin, plant extracts, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains height
Imitate anti-dandruff and itching-relieving hair lotion.
Embodiment 8
In the present embodiment, the component of hair lotion and the content of each component are as follows:
Preparation method: hair conditioner, acid-base modifier, thickener are added to the reactor equipped with 79.5Kg distilled water
In, under stiring in normal heating to 80 DEG C and in the temperature, obtains each component and be completely dissolved or evenly dispersed first
Mixed liquor；The propylene glycol of 2.5 times of new health azoles and its quality is heated to 80 DEG C under stiring and obtains new health azoles solution；By new health azoles
Solution, which is added 80 DEG C of the first mixed liquor and is uniformly mixed, obtains the second mixed liquor；Second mixed liquor is cooled to 45 DEG C, then according to
Secondary addition keratin, plant extracts, essence, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less i.e.
Obtain efficient anti-dandruff and itching-relieving hair lotion.
Embodiment 9
In the present embodiment, the component of hair lotion and the content of each component are as follows:
Preparation method: hair conditioner, acid-base modifier, thickener are added to the reaction equipped with 82.7Kg deionized water
In device, under stiring in normal heating to 70 DEG C and in the temperature, obtains each component and be completely dissolved or evenly dispersed
One mixed liquor；The propylene glycol of 2.5 times of new health azoles and its quality is heated to 80 DEG C under stiring and obtains new health azoles solution；By new health
Azoles solution, which is added 70 DEG C of the first mixed liquor and is uniformly mixed, obtains the second mixed liquor；Second mixed liquor is cooled to 45 DEG C, then
Keratin, plant extracts are sequentially added, and continues stirring to each component and is uniformly mixed, 40 DEG C or less is subsequently cooled to and obtains
Efficient anti-dandruff and itching-relieving hair lotion.
Embodiment 10
In the present embodiment, the component of hair lotion and the content of each component are as follows:
Preparation method: hair conditioner, acid-base modifier, thickener are added to equipped with the anti-of 79.25Kg deionized water
It answers in device, under stiring in normal heating to 75 DEG C and in the temperature, obtains each component and be completely dissolved or evenly dispersed
First mixed liquor；The propylene glycol of 2 times of new health azoles and its quality is heated to 75 DEG C under stiring and obtains new health azoles solution；By new health
Azoles solution, which is added 75 DEG C of the first mixed liquor and is uniformly mixed, obtains the second mixed liquor；Second mixed liquor is cooled to 45 DEG C, then
Keratin, plant extracts, preservative, essence are sequentially added, and continues stirring to each component and is uniformly mixed, is subsequently cooled to 40
DEG C or less obtain efficient anti-dandruff and itching-relieving hair lotion.
Embodiment 11
In the present embodiment, the component of hair lotion and the content of each component are as follows:
Preparation method: hair conditioner, acid-base modifier, thickener are added to the reaction equipped with 80.0Kg deionized water
In device, under stiring in normal heating to 70 DEG C and in the temperature, obtains each component and be completely dissolved or evenly dispersed
One mixed liquor；The propylene glycol of 2 times of new health azoles and its quality is heated to 75 DEG C under stiring and obtains new health azoles solution；By new health azoles
Solution, which is added 70 DEG C of the first mixed liquor and is uniformly mixed, obtains the second mixed liquor；Second mixed liquor is cooled to 45 DEG C, then according to
Secondary addition keratin, plant extracts, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains height
Imitate anti-dandruff and itching-relieving hair lotion.
Embodiment 12~16 is the preparation of hair film.
Embodiment 12
In the present embodiment, the component of hair film and the content of each component are as follows:
Preparation method: grease is added in oily phase pot, under stiring in normal heating to 60 DEG C；By hair conditioner,
Thickener is added in the water phase pot equipped with 75.4Kg deionized water, equal to each component under stiring in normal heating to 60 DEG C
Water phase mixed liquor is obtained after dissolution and is pumped into emulsion pot, then be will warm up 60 DEG C of grease and is pumped into emulsion pot, and
The Temperature Vacuum emulsifying for making the material in emulsion pot maintain 60 DEG C 15 minutes, obtains the first mixing paste；By new health azoles
It is heated to 75 DEG C under stiring with 3 times of propylene glycol of its quality and obtains new health azoles solution；New health azoles solution is added the of 60 DEG C
One mixing paste and be uniformly mixed obtain the second mixing paste, the second mixing paste is cooled to 45 DEG C, sequentially adds angle egg
White, plant extracts, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains efficient anti-dandruff and itching-relieving
Hair film.
Embodiment 13
In the present embodiment, the component of hair film and the content of each component are as follows:
Preparation method: grease is added in oily phase pot, under stiring in normal heating to 70 DEG C；By hair conditioner,
Thickener is added in the water phase pot equipped with 74.7Kg deionized water, equal to each component under stiring in normal heating to 70 DEG C
Water phase mixed liquor is obtained after dissolution and is pumped into emulsion pot, then be will warm up 70 DEG C of grease and is pumped into emulsion pot, and
The Temperature Vacuum emulsifying for making the material in emulsion pot maintain 70 DEG C 12 minutes, obtains the first mixing paste；By new health azoles
It is heated to 75 DEG C under stiring with 2.5 times of propylene glycol of its quality and obtains new health azoles solution；New health azoles solution is added 70 DEG C
First mixing paste and be uniformly mixed obtain the second mixing paste, the second mixing paste is cooled to 45 DEG C, sequentially adds angle
Albumen, plant extracts, essence, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains efficiently
Anti-dandruff and itching-relieving hair film.
Embodiment 14
In the present embodiment, the component of hair film and the content of each component are as follows:
Preparation method: grease is added in oily phase pot, under stiring in normal heating to 80 DEG C；By hair conditioner,
Thickener is added in the water phase pot equipped with 74.4Kg deionized water, equal to each component under stiring in normal heating to 80 DEG C
Water phase mixed liquor is obtained after dissolution and is pumped into emulsion pot, then be will warm up 80 DEG C of grease and is pumped into emulsion pot, and
The Temperature Vacuum emulsifying for making the material in emulsion pot maintain 80 DEG C 10 minutes, obtains the first mixing paste；By new health azoles
It is heated to 80 DEG C under stiring with 2 times of propylene glycol of its quality and obtains new health azoles solution；New health azoles solution is added the of 80 DEG C
One mixing paste and be uniformly mixed obtain the second mixing paste, the second mixing paste is cooled to 45 DEG C, sequentially adds angle egg
White, plant extracts, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains efficient anti-dandruff and itching-relieving
Hair film.
Embodiment 15
In the present embodiment, the component of hair film and the content of each component are as follows:
Preparation method: grease is added in oily phase pot, under stiring in normal heating to 75 DEG C；By hair conditioner,
Thickener is added in the water phase pot equipped with 70.45Kg distilled water, molten to each component under stiring in normal heating to 75 DEG C
Water phase mixed liquor is obtained after solution and is pumped into emulsion pot, then be will warm up 75 DEG C of grease and is pumped into emulsion pot, and makes
Material in emulsion pot maintains Temperature Vacuum emulsifying 10 minutes of 75 DEG C, obtains the first mixing paste；By new health azoles with
The propylene glycol of 2.5 times of its quality is heated to 75 DEG C under stiring and obtains new health azoles solution；New health azoles solution is added the of 75 DEG C
One mixing paste and be uniformly mixed obtain the second mixing paste, the second mixing paste is cooled to 45 DEG C, sequentially adds angle egg
White, plant extracts, preservative, essence, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains
Efficient anti-dandruff and itching-relieving hair film.
Embodiment 16
In the present embodiment, the component of hair film and the content of each component are as follows:
Preparation method: grease is added in oily phase pot, under stiring in normal heating to 65 DEG C；By hair conditioner,
Thickener is added in the water phase pot equipped with 72.9Kg deionized water, equal to each component under stiring in normal heating to 65 DEG C
Water phase mixed liquor is obtained after dissolution and is pumped into emulsion pot, then be will warm up 65 DEG C of grease and is pumped into emulsion pot, and
The Temperature Vacuum emulsifying for making the material in emulsion pot maintain 65 DEG C 15 minutes, obtains the first mixing paste；By new health azoles
It is heated to 75 DEG C under stiring with 3 times of propylene glycol of its quality and obtains new health azoles solution；New health azoles solution is added the of 65 DEG C
One mixing paste and be uniformly mixed obtain the second mixing paste, the second mixing paste is cooled to 45 DEG C, sequentially adds angle egg
White, plant extracts, and continue stirring to each component and be uniformly mixed, it is subsequently cooled to 40 DEG C or less and obtains efficient anti-dandruff and itching-relieving
Hair film.
17 chlosma drug sensitivity testing in vitro of embodiment
In the present embodiment, new health azoles is Chengdu Jia Ye Biotechnology Co., Ltd product, and husky fort fluid nutrient medium is the U.S.
Amresco Products, chlosma are the bacterial strain of U.S. ATCC.
(1) preparation of samples.Respectively by new health azoles, coptis extract, houttuynia extract, Cacumen Platycladi extract deionization
Water prepares the aqueous solution of weight concentration 10%, and sterilizes 20 minutes and save at 115 DEG C, is trained respectively with husky fort liquid using preceding
It supports base and dilutes 10 times, even if the weight concentration of new health azoles, coptis extract, houttuynia extract, Cacumen Platycladi extract is
1.0%.
(2) bacterial strain prepares.By chlosma continuous passage 2 times, when the 2nd secondary culture was by the 4th day, sterile physiological is used
Bacteria suspension is made in salt water, and counting contained bacterium number in bacteria suspension through cell counter is 1~2 × 109A/liter, it is used before being inoculated with
Husky fort fluid nutrient medium dilutes 10 times.
(3) it is inoculated with.100 microlitres of bacteria suspension prepared in every Kong Zhongjia above-mentioned steps (2) of 96 orifice plates, then by 96 orifice plates
It is divided into six groups, every group of 16 holes；First group is new health azoles group, and new 100 microlitres of health azoles solution that step (1) is prepared are added in every hole；
Second group is coptis extract group, and 100 microlitres of coptis extract liquid that step (1) is prepared are added in every hole；Third group is cordate houttuynia
100 microlitres of houttuynia extract liquid that step (1) is prepared are added in extract group, every hole；4th group is Cacumen Platycladi extract group, often
100 microlitres of Cacumen Platycladi extract liquid that step (1) is prepared are added in hole；5th group is composition group, and combination thing liquid 100 is added in every hole
Microlitre, new health azoles solution, the coptis extract liquid, houttuynia extract liquid, cacumen biotae that the combination thing liquid is prepared by step (1)
Extract liquid is 1:10:10:10 composition by volume；6th group is control group, and it is micro- that husky fort fluid nutrient medium 100 is added in every hole
It rises.Above-mentioned inoculated 96 orifice plate is placed in wet box, is cultivated 24~72 hours at 34 DEG C.
(4) result.Every hole bacterium solution in cultured 96 orifice plate of step (3) is counted with cell counter, with control group
The average value of contained bacterium number is 1, and the average value of bacterium number contained by other each groups is shown in Table relative to the calculated result containing bacterium number of control group
1:
Table 1
| First group | Second group | Third group | 4th group | 5th group | 6th group | |
| 24h | 0.31 | 0.40 | 0.40 | 0.45 | 0.20 | 1 |
| 48h | 0.29 | 0.37 | 0.43 | 0.37 | 0.18 | 1 |
| 72h | 0.28 | 0.35 | 0.40 | 0.34 | 0.15 | 1 |
Test result shows new health azoles group, coptis extract group, houttuynia extract group, Cacumen Platycladi extract group and group
Closing object group has stronger inhibiting effect to chlosma, but composition group is most strong to the inhibiting effect of chlosma.
18 chlosma drug resistance in vitro test of embodiment
In the present embodiment, new health azoles, husky fort fluid nutrient medium and the chlosma used is identical as embodiment 17.
(1) preparation of samples.Respectively by new health azoles, coptis extract, houttuynia extract, Cacumen Platycladi extract deionization
Water prepares the aqueous solution of weight concentration 10%, and sterilizes 20 minutes and save at 115 DEG C, is trained respectively with husky fort liquid using preceding
It supports base and dilutes 10 times, even if the weight concentration of new health azoles, coptis extract, houttuynia extract, Cacumen Platycladi extract is
1.0%.
(2) antibody-resistant bacterium prepares.By chlosma continuous passage 2 times, in the 3rd passage by chlosma respectively with step
Suddenly (1) is prepared new health azoles solution, coptis extract liquid, houttuynia extract liquid, Cacumen Platycladi extract liquid co-incubation and again
Passage 2 times is eluted with sterile saline respectively when the 2nd time after passage was by the 4th day, four kinds of bacteria suspensions is obtained, through thin
Born of the same parents' calculating instrument counts, and is 1-2 × 10 containing bacterium number9A/liter；By above-mentioned 4 kinds of bacteria suspensions, 1:1:1:1 is mixed by volume, inoculation
It is preceding to dilute 10 times with husky fort fluid nutrient medium.
(3) it is inoculated with.Every hole adds prepared by step (2) 100 microlitres of plastc ring in 48 orifice plates, then by 48 orifice plates point
It is two groups, every group of 24 holes；First group is composition group, and 100 microlitres of thing liquid of combination is added in every hole, and the combination thing liquid is by step
(1) new health azoles solution, coptis extract liquid, houttuynia extract liquid, the Cacumen Platycladi extract liquid prepared are 1:10 by volume:
10:10 composition；Second group is control group, and husky 100 microlitres of fluid nutrient medium of fort is added in every hole.Above-mentioned inoculated 48 orifice plate is set
In in wet box, cultivated 24~72 hours at 34 DEG C.
(4) result.Every hole bacterium solution in cultured 48 orifice plate of step (3) is counted with cell counter, with control group
The average value of contained bacterium number is 1, and the average value of bacterium number contained by composition group is shown in Table relative to the calculated result containing bacterium number of control group
2:
Table 2
| First group | Second group | |
| 24h | 0.31 | 1 |
| 48h | 0.27 | 1 |
| 72h | 0.21 | 1 |
Test result shows composition group to by new health azoles, coptis extract, houttuynia extract, side blinds extract
The drug-fast bacteria generated respectively has apparent inhibiting effect.
The test of 19 anti-inflammatory of embodiment
In the present embodiment, IL-6 (interleukin-6) kit, TNF-α (tumor necrosis factor) kit are Sai Mofei company
Product, Normal human dermal's cell are ATCC Products.
A, B, C, D, E, F, G group are set, A group, the new health azoles solution of mass concentration 0.5% are respectively as follows:；B group, mass concentration
5.0% coptis extract solution；C group, the houttuynia extract solution of mass concentration 5.0%；D group, the side of mass concentration 5.0%
Blinds extract solution；E group, the keratin solution of mass concentration 1.0%；F group: the new health azoles solution of mass concentration 0.5%, quality
5.0% coptis extract solution of concentration, the houttuynia extract solution of mass concentration 5.0%, mass concentration 5.0% side blinds
The keratin solution composition solution that 1:1:1:1:1 is mixed to form by volume of extract solution, mass concentration 1.0%；G
Group: distilled water.
Respectively by the solution and IL-6 (interleukin-6) kit and TNF-α (tumor necrosis factor in A, B, C, D, E, F, G group
Son) the positive agent of kit institute band is mixed to form 14 kinds of positive agent culture solutions, Normal human dermal's cell is respectively placed in 14
In kind culture solution, cultivated 24 hours under saturated humidity, 37 DEG C of constant temperature, 5v.% carbon dioxide conditions using high glucose medium.Training
It after supporting, carries out ELISA test (enzyme-linked immunosorbent), respectively using IL-6 (interleukin-6) kit measurement IL-6's
Expression, the expression of TNF-α (tumor necrosis factor) kit measurement TNF-α.Test result is shown in Table 3:
Table 3
| A | B | C | D | E | F | G | |
| IL-6 | 93 | 36 | 60 | 72 | 56 | 30 | 100 |
| TNF-α | 95 | 34 | 54 | 69 | 53 | 28 | 100 |
Test result shows the expression of inhibition inflammatory factor IL-6 and TNF-α in dermal cell, and (composition is molten for F group
Liquid) effect it is best, thus F group (composition solution) can effectively inhibit the generation of scalp inflammation.
The dandruff inhibitory effect of 20 hair-washing hair-care articles of embodiment is tested
(1) test sample
Sample A, above-described embodiment 4 prepare shampoo；
Sample B removes the shampoo of anti-dandruff anti-pruritic compositions by the constituent component of above-described embodiment 4, it may be assumed that
Sample C, hair lotion prepared by above-described embodiment 9；
Sample D removes the hair lotion of anti-dandruff anti-pruritic compositions by the constituent component of above-described embodiment 9, it may be assumed that
Sample E, hair film prepared by above-described embodiment 14；
Sample F removes the hair film of anti-dandruff anti-pruritic compositions by the constituent component of above-described embodiment 14, it may be assumed that
(2) half a head is tested
Each 10 people of men and women is chosen, its hair is divided equally into two halves hair from centre respectively, uses shampoo sample A, sample respectively
Product B is respectively washed 5 minutes, then cleans 3 times with warm water respectively, and 1 minute every time, then natural air drying.24 hours, 48 hours, 72
Hour observes the quantity (unit: a) for counting every subject's dandruff respectively, takes the average value of 10 people.
Each 10 people of men and women is chosen, with shampoo sample B wash my hair 5 minutes, then its hair is divided equally into two from centre respectively
Half hair is nursed 3 minutes with hair lotion sample C, sample D respectively, then is cleaned 2 times with warm water, 1 minute every time, then natural
It air-dries.Every subject of counting is observed respectively 24 hours, 48 hours, 72 hours and the quantity (unit: a) of dandruff occurs, is taken
The average value of 10 people.
Each 10 people of men and women is chosen, cleans 3 times with shampoo sample B wash my hair 5 minutes, and with warm water, 1 minute every time,
Its hair is divided equally into two halves hair from centre respectively again, is uniformly applied on half hair with hair film sample E, 2 grams of sample F respectively,
Then natural air drying.Every subject of counting is observed respectively 24 hours, 48 hours, 72 hours the quantity (list of dandruff occurs
Position: a), take the average value of 10 people.
(3) result test result is shown in Table 4:
Table 4
| A | B | C | D | E | F | |
| 24 hours | 8 | 62 | 24 | 70 | 19 | 69 |
| 48 hours | 49 | 171 | 78 | 189 | 57 | 185 |
| 72 hours | 123 | 376 | 184 | 385 | 143 | 379 |
Test result shows that sample A, sample C, sample E dandruff inhibitory effect are substantially better than sample B, sample D, sample
Product F, it was demonstrated that hair-washing hair-care articles of the present invention have the function of excellent inhibition dandruff.
21 shampoo of embodiment comb resistance wet on hair, dry comb resistance, tensile strength, brightness influence test
(1) test sample
Sample A, above-described embodiment 4 prepare shampoo；
Sample B removes the shampoo of anti-dandruff anti-pruritic compositions by the constituent component of above-described embodiment 4, it may be assumed that
(2) topknot pre-processes
After big topknot (Asia human hair) is cleaned with the sodium dodecyl sulfate solution of mass concentration 3%, in ether
It impregnates 24 hours, the small topknot of ether treated topknot the is made long 23cm of multi beam, weight 3g moistens each small topknot distilled water
After wet, rubbed wash 2~3 minutes with the sodium dodecyl sulfate solution 2g of mass concentration 3% respectively, then rinsed well with flowing water,
Naturally dry is stand-by.
(3) experimental procedure
1. wet comb resistance measurement: take each 3 grams of shampoo sample A, sample B be respectively used to rub wash it is a branch of by step (2) in advance locate
The small topknot of long 23cm after reason, weight 3g, rubbing and washing the time is 5 minutes, is then rinsed 2 minutes with 40 DEG C of constant streams respectively, general
Washed two beam Hair grooming Texture instruments (BROOKFIELD, CT3-2K) test.
2. dry comb resistance measurement: taking each 3 grams of shampoo sample A, sample B to be respectively used to rub to wash and a branch of locate in advance by step (2)
The small topknot of long 23cm after reason, weight 3g, rubbing and washing the time is 5 minutes, then respectively with 40 DEG C constant streams flushing 2 minutes, then
With hot hair dryer by hair dryer, two beam Hair grooming Texture instruments (BROOKFIELD, CT3-2K) of drying are tested after.
3. average tensile strength test: take each 3 grams of shampoo sample A, sample B be respectively used to rub wash it is a branch of by step (2)
The small topknot of pretreated long 23cm, weight 3g, rubbing and washing the time is 5 minutes, then respectively with 2 points of 40 DEG C of constant streams flushings
Hair dryer is respectively taken 5 hairs to be fixed on Texture instrument by clock, reusable heat hair dryer respectively after from the topknot that two beams dry up
The both ends (BROOKFIELD, CT3-2K), starting upper end is pulled up, until hairs break.
4. brightness test: take each 3 grams of shampoo sample A, sample B be respectively used to rub wash it is a branch of by step (2) pre-process
The small topknot of rear long 23cm, weight 3g, rubbing and washing the time is 5 minutes, then respectively with 40 DEG C constant streams flushing 2 minutes, then use
Hot hair dryer is by hair dryer, after combing the topknot that two beams dry up with comb after, is organized into the plate that width is 2cm respectively
Shape is fixed in standard sources VERIVIDE COLOR ASSESMENT CABINET, evaluates the light of each beam hair by 5 points of code of points processed by trained evaluator
Degree, 1 point be it is dark, 5 points be it is bright.
Test result sees below each table:
The wet comb resistance (unit: newton) of table 5
| Sample | Shampoo sample A | Shampoo sample B |
| Resistance | 43 | 47 |
The dry comb resistance (unit: newton) of table 6
| Sample | Shampoo sample A | Shampoo sample B |
| Resistance | 49 | 53 |
7 tensile strength of table (unit: newton)
| Sample | Shampoo sample A | Shampoo sample B |
| Resistance | 152 | 117 |
8 brightness of table
| Sample | Shampoo sample A | Shampoo sample B |
| Score | 5 | 5 |
Test result shows the shampoo of composition containing anti-dandruff and itching-relieving of the present invention to wet comb resistance, dry comb resistance, tension
Intensity, brightness etc. have no significant effect.
22 hair lotion of embodiment comb resistance wet on hair, dry comb resistance, tensile strength, brightness influence test
(1) sample preparation
Sample C, hair lotion prepared by above-described embodiment 9；
Sample D removes the hair lotion of anti-dandruff anti-pruritic compositions by the constituent component of above-described embodiment 9, it may be assumed that
(2) topknot pre-processes:
After big topknot (Asia human hair) is cleaned with the sodium dodecyl sulfate solution of mass concentration 3%, in ether
It impregnates 24 hours, the small topknot of ether treated topknot the is made long 23cm of multi beam, weight 3g moistens each small topknot distilled water
After wet, rubbed wash 2~3 minutes with the sodium dodecyl sulfate solution 2g of mass concentration 3% respectively, then rinsed well with flowing water,
Naturally dry is stand-by.
(3) experimental procedure
1. wet comb resistance measurement: take each 3 grams of hair lotion sample C, sample D be respectively used to rub wash it is a branch of by step (2) in advance locate
The small topknot of long 23cm after reason, weight 3g, rubbing and washing the time is 3 minutes, is then rinsed 2 minutes with 40 DEG C of constant streams respectively, general
Washed two beam Hair grooming Texture instruments (BROOKFIELD, CT3-2K) test.
2. dry comb resistance measurement: taking each 3 grams of hair lotion sample C, sample D to be respectively used to rub to wash and a branch of locate in advance by step (2)
The small topknot of long 23cm after reason, weight 3g, rubbing and washing the time is 3 minutes, then respectively with 40 DEG C constant streams flushing 2 minutes, then
With hot hair dryer by hair dryer, two beam Hair grooming Texture instruments (BROOKFIELD, CT3-2K) of drying are tested after.
3. average tensile strength test: take each 3 grams of hair lotion sample C, sample D be respectively used to rub wash it is a branch of by step (2)
The small topknot of pretreated long 23cm, weight 3g, rubbing and washing the time is 3 minutes, then respectively with 2 points of 40 DEG C of constant streams flushings
Hair dryer is respectively taken 5 hairs to be fixed on Texture instrument by clock, reusable heat hair dryer respectively after from the topknot that two beams dry up
The both ends (BROOKFIELD, CT3-2K), starting upper end is pulled up, until hairs break.
4. brightness test: take each 3 grams of hair conditioner sample C, sample D be respectively used to rub wash it is a branch of by step (2) pre-process
The small topknot of rear long 23cm, weight 3g, rubbing and washing the time is 3 minutes, then respectively with 40 DEG C constant streams flushing 2 minutes, then use
Hot hair dryer is by hair dryer, after combing the topknot that two beams dry up with comb after, is organized into the plate that width is 2cm respectively
Shape is fixed in standard sources VERIVIDE COLOR ASSESMENT CABINET, evaluates the light of each beam hair by 5 points of code of points processed by trained evaluator
Degree, 1 point be it is dark, 5 points be it is bright.
Test result sees below each table:
The wet comb resistance (unit: newton) of table 9
| Sample | Hair lotion sample C | Hair lotion sample D |
| Resistance | 39 | 41 |
The dry comb resistance (unit: newton) of table 10
| Sample | Hair lotion sample C | Hair lotion sample D |
| Resistance | 33 | 39 |
11 tensile strength of table (unit: newton)
| Sample | Hair lotion sample C | Hair lotion sample D |
| Resistance | 128 | 113 |
12 brightness of table
| Sample | Hair lotion hair conditioner sample C | Hair lotion sample D |
| Score | 5 | 5 |
Test result shows the hair lotion of the composition of the present invention containing anti-dandruff and itching-relieving to wet comb resistance, dry comb resistance, anti-
Tensile strength, brightness etc. have no significant effect.
23 hair film of embodiment comb resistance wet on hair, dry comb resistance, tensile strength, brightness influence test
(1) sample preparation
Sample E, hair film prepared by above-described embodiment 14；
Sample F removes the hair film of anti-dandruff anti-pruritic compositions by the constituent component of above-described embodiment 14, it may be assumed that
(2) topknot pre-processes:
After big topknot (Asia human hair) is cleaned with the sodium dodecyl sulfate solution of mass concentration 3%, in ether
It impregnates 24 hours, the small topknot of ether treated topknot the is made long 23cm of multi beam, weight 3g moistens each small topknot distilled water
After wet, rubbed wash 2~3 minutes with the sodium dodecyl sulfate solution 2g of mass concentration 3% respectively, then rinsed well with flowing water,
Naturally dry is stand-by.
(3) experimental procedure
1. wet comb resistance measurement: taking each 1 gram of hair film sample E, sample F, to be respectively used to rub painting uniformly a branch of pre- by step (1)
The small topknot of treated long 23cm, weight 3g will be rubbed and applies uniform two beams Hair grooming Texture instrument (BROOKFIELD, CT3-2K) and survey
Examination.
2. dry comb resistance measurement: take each 1 gram of hair film sample E, sample F be respectively used to rub painting it is uniformly a branch of pre- by step (1)
The small topknot of treated long 23cm, weight 3g, and with hot hair dryer by hair dryer, by two beam Hair grooming textures of drying after
Instrument (BROOKFIELD, CT3-2K) test.
3. average tensile strength is tested: taking each 1 gram of hair film sample E, sample F, to be respectively used to rub painting uniformly a branch of by step
(1) the small topknot of pretreated long 23cm, weight 3g, reusable heat hair dryer is by hair dryer, from the topknot of two beams drying after
Middle that 5 hairs is respectively taken to be fixed on the both ends Texture instrument (BROOKFIELD, CT3-2K) respectively, starting upper end is pulled up, until hair
Fracture.
4. brightness is tested: taking each 1 gram of hair film sample E, sample F to be respectively used to rub, painting is uniformly a branch of locates in advance by step (1)
The topknot that two beams dry up is combed hair dryer by the small topknot of long 23cm, weight 3g after reason, reusable heat hair dryer after with comb
After reason, it is organized into the tabular that width is 2cm respectively, is fixed in standard sources VERIVIDE COLOR ASSESMENT CABINET, presses 5 points by trained evaluator
Code of points processed evaluates the brightness of each beam hair, 1 point be it is dark, 5 points are bright.
Test result sees below each table:
The wet comb resistance (unit: newton) of table 13
The dry comb resistance (unit: newton) of table 14
| Sample | Hair film sample E | Hair film sample F |
| Resistance | 40 | 41 |
15 tensile strength of table (unit: newton)
| Sample | Hair film sample E | Hair film sample F |
| Resistance | 121 | 116 |
16 brightness of table
| Sample | Hair film sample E | Hair film sample F |
| Score | 5 | 5 |
Test result shows the hair film of the composition of the present invention containing anti-dandruff and itching-relieving to wet comb resistance, dry comb resistance, tension
Intensity, brightness etc. have no significant effect.
Claims (10)
1. efficient anti-dandruff and itching-relieving shampoo, it is characterised in that the shampoo contains anti-dandruff and itching-relieving composition, the anti-dandruff and itching-relieving group
Close the mass fraction of the component and each component of object in shampoo are as follows: new health azoles 0.1~1%, plant extracts 0.5~10%,
Keratin 0.1~2%；
The plant extracts is made of coptis extract, houttuynia extract and Cacumen Platycladi extract, coptis extract, fish raw meat
Careless extract, Cacumen Platycladi extract mass ratio be 1:1:1.
2. efficient anti-dandruff and itching-relieving shampoo according to claim 1, it is characterised in that the shampoo also contains following quality point
Several components:
The pure water is deionized water or distilled water.
3. the efficient anti-dandruff and itching-relieving shampoo according to Claims 2 or 3, it is characterised in that:
The surfactant is laureth ammonium sulfate, Texapon Special, laureth sodium sulfovinate, laruyl alcohol are poly-
Ether carboxylic acid sodium, sodium lauroyl sarcosine, lauroyl glycine potassium, laruyl alcohol sodium sulfovinate, laureth sulfosuccinic acid
At least two in ester disodium；
The submissive conditioner is dimethyl silicone polymer, dimethiconol, ammonia-terminated polydimethylsiloxane, amino pair
Propyl dimethyl silicone polymer, Polyquaternium-10, polyquaternium -7, polyquaternium -47, PEG-7 glyceryl cocoate, melon
Glue hydroxypropyl-trimethyl ammonium chloride, hydroxypropyl guar hydroxypropyltrimonium chloride, polyethylene glycol -14M, polyethylene glycol -7M
In at least two；
The acid-base modifier be citric acid, lactic acid, sodium lactate, triethanolamine, sodium citrate, EDTA and its sodium salt at least
It is a kind of；
The thickener is cocounut oil alkanol amides, coconut oleoyl amine DEA, coconut oleoyl amine MEA, coconut oleoyl amine methyl MEA, cocounut oil acyl
Amine MIPA, Cocoamidopropyl betaine, lauryl betaine, lauryl hydroxyl sulphur glycine betaine, lauryl glucoside, lauric acid are sweet
Grease, lauryl alcohol lactate, Sodium Lauroamphoacetate, cetostearyl alcohol, cetanol, xanthan gum, carbomer and polypropylene
At least two in acid.
4. efficient anti-dandruff and itching-relieving hair lotion, it is characterised in that the hair lotion contains anti-dandruff and itching-relieving composition, the anti-dandruff and itching-relieving group
Close the mass fraction of the component and each component of object in hair lotion are as follows: new health azoles 0.1~1%, plant extracts 0.5~10%,
Keratin 0.1~2%；
The plant extracts is made of coptis extract, houttuynia extract and Cacumen Platycladi extract, coptis extract, fish raw meat
Careless extract, Cacumen Platycladi extract mass ratio be 1:1:1.
5. efficient anti-dandruff and itching-relieving hair lotion according to claim 4, it is characterised in that the hair lotion also contains following quality point
Several components:
The pure water is deionized water or distilled water.
6. efficient anti-dandruff and itching-relieving hair lotion according to claim 4 or 5, it is characterised in that:
The hair conditioner is behenyl base trimethyl ammonium chloride, behenyl base trimethyl ammonium sulfate, stearyl trimethyl chlorination
Ammonium, cetrimonium chloride, dimethyl silicone polymer, ring five dimethyl silicone polymer, dimethiconol, aminopropyl poly dimethyl
Siloxanes, Polyquaternium-10, polyquaternium -7, guar hydroxypropyltrimonium chloride, gathers at ammonia-terminated polydimethylsiloxane
Ethylene glycol -14M, polyethylene glycol -7M, at least two in polyethylene glycol -90M；
The acid-base modifier is at least one of citric acid, lactic acid, glutamic acid, phosphoric acid, EDTA and its sodium salt；
The thickener is cetanol, cetostearyl alcohol, docosyl alcohol, ceteareth -25, stearine, poly- season
Ammonium salt -37, ceteareth -20, xanthan gum, acrylate copolymer, hydroxyethyl cellulose, in hydroxypropyl methyl cellulose
At least one.
7. efficient anti-dandruff and itching-relieving hair film, it is characterised in that the hair film contains anti-dandruff and itching-relieving composition, the anti-dandruff and itching-relieving composition
Mass fraction in hair film of component and each component are as follows: new health azoles 0.1~1%, plant extracts 0.5~10%, keratin
0.1~2%；
The plant extracts is made of coptis extract, houttuynia extract and Cacumen Platycladi extract, coptis extract, fish raw meat
Careless extract, Cacumen Platycladi extract mass ratio be 1:1:1.
8. efficient anti-dandruff and itching-relieving hair film according to claim 7, it is characterised in that the hair film also contains following mass fraction
Component:
The pure water is deionized water or distilled water.
9. according to the efficient anti-dandruff and itching-relieving hair film of claim 7 or 8, it is characterised in that:
The grease is dormant oil, isoparaffin, avocado oil, jojoba oil, isopropyl myristate, isopropyl palmitate, hydrogenation
Poly decene, dimethyl silicone polymer, ring five dimethyl silicone polymer, dimethiconol, aminopropyl polydimethylsiloxanes
At least one of alkane, ammonia-terminated polydimethylsiloxane；
The hair conditioner is behenyl base trimethyl ammonium chloride, behenyl base trimethyl ammonium sulfate, stearyl trimethyl chlorination
Ammonium, cetrimonium chloride, VARISOFT TA100, Polyquaternium-10, polyquaternium -7, melon rubber Hydroxyproyl Trimethyl chlorine
Change ammonium, polyethylene glycol -14M, polyethylene glycol -7M, at least two in polyethylene glycol -90M；
The thickener is cetanol, cetostearyl alcohol, docosyl alcohol, ceteareth -25, stearine, poly- season
Ammonium salt -37, ceteareth -20, xanthan gum, acrylate copolymer, hydroxyethyl cellulose, in hydroxypropyl methyl cellulose
At least one.
10. according to claim 1, the efficient anti-dandruff and itching-relieving shampoo of 2,4,5,7 or 8, hair lotion or hair film, it is characterised in that
It further include essence or/and preservative, the mass fraction of the essence is 0.1%~1%, and the mass fraction of the preservative is
0.05%~0.1%.
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Cited By (6)
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| CN112932997A (en) * | 2020-10-21 | 2021-06-11 | 李平 | Wash-free shampoo film and preparation method thereof |
| CN113633579A (en) * | 2021-08-14 | 2021-11-12 | 广州市丝露杰精细化工有限公司 | Color-locking hair-care essential oil and preparation method thereof |
| CN114796047A (en) * | 2022-04-20 | 2022-07-29 | 广州市科能化妆品科研有限公司 | Anti-dandruff composition, application of anti-dandruff composition, shampoo and preparation method of shampoo |
| CN115177546A (en) * | 2022-08-26 | 2022-10-14 | 广州好迪集团有限公司 | Non-irritant high-efficiency anti-dandruff composition and anti-dandruff shampoo |
| CN115252474A (en) * | 2022-07-29 | 2022-11-01 | 惠州市肌缘生物科技股份有限公司 | Shampoo explosive salt block and preparation method thereof |
| CN115554211A (en) * | 2021-07-01 | 2023-01-03 | 遵义医科大学 | Dendrobium stem shampoo |
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| CN112932997A (en) * | 2020-10-21 | 2021-06-11 | 李平 | Wash-free shampoo film and preparation method thereof |
| CN115554211A (en) * | 2021-07-01 | 2023-01-03 | 遵义医科大学 | Dendrobium stem shampoo |
| CN113633579A (en) * | 2021-08-14 | 2021-11-12 | 广州市丝露杰精细化工有限公司 | Color-locking hair-care essential oil and preparation method thereof |
| CN114796047A (en) * | 2022-04-20 | 2022-07-29 | 广州市科能化妆品科研有限公司 | Anti-dandruff composition, application of anti-dandruff composition, shampoo and preparation method of shampoo |
| CN115252474A (en) * | 2022-07-29 | 2022-11-01 | 惠州市肌缘生物科技股份有限公司 | Shampoo explosive salt block and preparation method thereof |
| CN115252474B (en) * | 2022-07-29 | 2024-05-24 | 惠州市肌缘生物科技股份有限公司 | Shampoo explosive salt block and preparation method thereof |
| CN115177546A (en) * | 2022-08-26 | 2022-10-14 | 广州好迪集团有限公司 | Non-irritant high-efficiency anti-dandruff composition and anti-dandruff shampoo |
| CN115177546B (en) * | 2022-08-26 | 2023-09-26 | 广州好迪集团有限公司 | Non-irritating high-efficiency anti-dandruff composition and anti-dandruff shampoo |
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