CN110221088A - Liquid driving device and liquid sample detection device - Google Patents
Liquid driving device and liquid sample detection device Download PDFInfo
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- CN110221088A CN110221088A CN201910643573.9A CN201910643573A CN110221088A CN 110221088 A CN110221088 A CN 110221088A CN 201910643573 A CN201910643573 A CN 201910643573A CN 110221088 A CN110221088 A CN 110221088A
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- liquid
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- transmission component
- driving device
- liquid container
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- 239000007788 liquid Substances 0.000 title claims abstract description 172
- 238000001514 detection method Methods 0.000 title claims abstract description 15
- 230000006835 compression Effects 0.000 claims abstract description 74
- 238000007906 compression Methods 0.000 claims abstract description 74
- 230000000712 assembly Effects 0.000 claims abstract description 38
- 238000000429 assembly Methods 0.000 claims abstract description 38
- 230000005540 biological transmission Effects 0.000 claims abstract description 36
- 230000033001 locomotion Effects 0.000 claims description 11
- 239000003153 chemical reaction reagent Substances 0.000 claims description 9
- 238000003745 diagnosis Methods 0.000 claims description 9
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 9
- 230000008878 coupling Effects 0.000 claims description 8
- 238000010168 coupling process Methods 0.000 claims description 8
- 238000005859 coupling reaction Methods 0.000 claims description 8
- 238000012544 monitoring process Methods 0.000 abstract description 2
- 238000010586 diagram Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 210000004907 gland Anatomy 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000009007 Diagnostic Kit Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004377 microelectronic Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
Abstract
The present invention provides a kind of liquid driving device and liquid sample detection devices, are related to the technical field of biological monitoring, and liquid driving device includes motor, transmission component and compression assemblies；The power output axis connection of transmission component and motor；Transmission component is connect with compression assemblies, to drive the working end of compression assemblies to move towards the direction close to or far from liquid container.By the rotation of motor, working end can be enabled to act on liquid container, change the volume of liquid container by squeezing liquid container, to complete the behavior of liquid in driving liquid container.The setting of single motor can replace operated pneumatic valve in the prior art and gas source, therefore reduce the volume of equipment, enable instrument miniaturization, improve the portability of instrument.
Description
Technical field
The present invention relates to biological monitoring technical fields, set more particularly, to a kind of liquid driving device and liquid sample detection
It is standby.
Background technique
It is micro-fluidic to refer to minute fluid is handled or manipulated using microchannel (having a size of tens of to hundreds of microns) that (volume is
Nanoliter arrive A Sheng) system involved in Science and Technology, be one and be related to chemistry, fluid physics, microelectronics, new material, life
The emerging cross discipline of object and biomedical engineering.Because having many characteristics, such as micromation, integrated, micro fluidic device usually quilt
Referred to as micro-fluidic chip, also referred to as chip lab and micro-total analysis system.Currently, micro-fluidic be considered grinding in biomedicine
There is huge development potentiality and broad application prospect in studying carefully.
Micro-fluidic chip includes driving testing circuit, for the location of being driven to drop and detecting drop etc.
Physical parameter.Currently used micro-fluidic liquid driven technology is: carrying out gas inflation/deflation using operated pneumatic valve, makes micro-fluidic core
The notacoria that piece builds conjunction is heaved, is shunk, to play the role of controlling liquid flowing in runner.
But due to needing to use special gas source using operated pneumatic valve driving liquid, the volume of equipment is often very
Greatly, the miniaturization of instrument and portability is caused to will receive influence.
Summary of the invention
The purpose of the present invention is to provide a kind of liquid driving device and liquid sample detection devices, to alleviate existing skill
Micro-fluidic liquid driven body present in art needs special gas source, therefore the volume of equipment is often very big, causes instrument
The technical issues of miniaturization will receive influence with portability.
Liquid driving device provided by the invention, including motor, transmission component and compression assemblies；
The power output axis connection of transmission component and motor；Transmission component is connect with compression assemblies, to drive compression assemblies
Working end towards close to or far from liquid container direction move.
Further, compression assemblies include compression bar arm, connector and return unit；
Be provided with working end on compression bar arm, connector and return unit are separately positioned on the two sides of compression bar arm, and connector and
Return unit is abutted with compression bar arm respectively；Transmission component can be press-connected part, reset so that compression bar arm be driven to compress or unclamp
Part, so that working end is able to carry out reciprocating motion.
Further, transmission component includes shaft coupling, screw rod, attachment base, sliding block and bearing block；
The both ends of shaft coupling are connect with the power output shaft of motor and screw rod respectively；Screw rod is threaded through in bearing block；Connection
Seat is mounted on screw rod, and attachment base can be moved back and forth along the extending direction of screw rod；Attachment base is connect with sliding block；
The protrusion that is on one side provided with rake and plane of the sliding block close to connector；Protrusion setting is separate in rake
One end of working end；
When connector and rake or protrusion cooperate, compression bar arm compresses return unit.
Further, rake, protrusion and compression assemblies are multiple, and quantity is equal.
Further, liquid driving device further includes pedestal；Transmission component further includes guide part；
Motor, compression assemblies, transmission component are respectively mounted on the base；
Sliding block is arranged over the guide, and sliding block can be moved back and forth along the extending direction of guide part.
Further, compression assemblies further include shaft；
Shaft is installed on the base；The one end of compression bar arm far from working end and shaft are rotatablely connected.
Further, present invention offer additionally provides a kind of liquid sample detection device, and liquid sample detection device includes
External diagnosis reagent case and liquid driving device；
Liquid container setting is in vitro on diagnostic kit.
Further, liquid sample detection device further includes controller；
The flow channel for liquids for being provided with liquid-level switch on external diagnosis reagent case and being connected to liquid container；Liquid-level switch setting
On flow channel for liquids；Controller is connect with liquid-level switch and motor respectively；
Liquid-level switch is used to detect the location information of liquid in flow channel for liquids, and location information is passed to controller；Control
Device processed is used to control the output pulse of motor.
Liquid driving device provided by the invention, in use, motor rotation is squeezed to be driven by transmission component
Press component movement.When moving when the working end of compression assemblies towards the direction close to liquid container, working end squeezes liquid container, enables
The volume of liquid container reduces, so that liquid be squeezed out；It is moved when the working end of compression assemblies towards the direction far from liquid container
When, the volume of liquid container increases.
From the foregoing, it will be observed that working end can be enabled to act on liquid container by the rotation of motor, by squeezing liquid container
Change the volume of liquid container, to complete the behavior of liquid in driving liquid container.The setting of single motor can replace
Operated pneumatic valve and gas source in the prior art, therefore the volume of equipment is reduced, instrument miniaturization is enabled, the portable of instrument is improved
Property.
Detailed description of the invention
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art
Embodiment or attached drawing needed to be used in the description of the prior art be briefly described, it should be apparent that, it is described below
Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor
It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is liquid driving device structural schematic diagram provided in an embodiment of the present invention；
Fig. 2 is liquid driving device sectional view provided in an embodiment of the present invention；
Fig. 3 is the structural schematic diagram of working end provided in an embodiment of the present invention and liquid container cooperation；
Fig. 4 is the structural schematic diagram of sliding block provided in an embodiment of the present invention；
Fig. 5 is the external structural schematic diagram for being directed to kit provided in an embodiment of the present invention；
Fig. 6 is the external sectional view for being directed to kit provided in an embodiment of the present invention.
Icon: 1- motor；2- transmission component；3- compression assemblies；The working end 4-；5- liquid container；6- rake；7- protrusion
Portion；8- pedestal；9- guide part；10- shaft；12- external diagnosis reagent case；13- liquid-level switch；14- flow channel for liquids；15- gland；
201- shaft coupling；202- screw rod；203- attachment base；204- sliding block；205- bearing block；301- compression bar arm；302- connector；303-
Return unit.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with embodiment, it is clear that described reality
Applying example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field
Art personnel every other embodiment obtained without making creative work belongs to the model that the present invention protects
It encloses.
As shown in Figure 1-Figure 3, liquid driving device provided in this embodiment, including motor 1, transmission component 2 and extruding
Component 3；The power output axis connection of transmission component 2 and motor 1；Transmission component 2 is connect with compression assemblies 3, to drive extruding group
The working end 4 of part 3 is moved towards the direction close to or far from liquid container 5.
Wherein, compression assemblies 3 may include pressure ram, roller bearing and reset spring.Transmission component 2 may include lead screw,
Gear set, sliding part and the connection component being connect with pressure ram.The power output shaft of motor 1 is connected by gear set and lead screw
It connects, to drive lead screw to rotate；Sliding part is connect with connection component, and connection component is mounted on lead screw, and connection component being capable of edge
The extending direction of lead screw moves back and forth, so that sliding part be driven to move back and forth.Be provided on sliding part matched with roller bearing it is recessed
Concave portion；Roller bearing and reset spring are separately positioned on the both ends of pressure ram, and roller bearing and reset spring are abutted with pressure ram respectively.?
In use process, the rotation of motor 1 drives lead screw rotation, connection component and sliding part to move back and forth along the extending direction of lead screw；When
When sliding part squeezes roller bearing to squeeze pressure ram, the working end 4 of pressure ram squeezes liquid container 5, while pressure ram squeezes again
Position spring；When the recessed portion on sliding part cooperates with roller bearing, reset spring resets at this time, to drive pressure ram far from liquid
Container 5, stopping squeeze liquid container 5.
Specifically, user can control the speed of service of transmission component 2, in turn by the velocity of rotation of control motor 1
It is converted into the speed of the close or separate liquid container 5 in 3 working end of control compression assemblies 4, thus, it is possible to influence liquid container 5 to hold
The speed of product variation, to directly affect the flow velocity of liquid in liquid container 5.
When 4 compressed liquid container 5 of working end, such as: the liquid flow when 4 compressed liquid packet of working end, in liquid packet
Enter into flow channel for liquids 14.When mobile towards the direction far from liquid container 5 when working end 4, it is true that the inside of liquid packet forms part
Sky, liquid packet carry out pumpback to liquid, to realize the flow direction of control liquid.Therefore, user can be turned by control motor 1
Dynamic direction controls the flow direction of liquid in liquid container 5.
User can realize the control to fluid flow by the stepping-in amount of control motor 1.Such as: the step pitch of motor 1
Angle is 0.72 °, and 1 maximum of motor can make the separation of 250 equal portions, and the lead of lead screw is 2mm, and user can pass through the step of control motor 1
Input drives the other fluid flow of micro updating to realize.
Specifically, the working end 4 of compression assemblies 3 can be pressure head.
Liquid container 5 selects elastic material to be made.
Liquid driving device provided in this embodiment, including motor 1, transmission component 2 and compression assemblies 3；Transmission component 2
With the power output axis connection of motor 1；Transmission component 2 is connect with compression assemblies 3, to drive the working end 4 of compression assemblies 3 towards leaning on
Close or direction far from liquid container 5 moves.In use, motor 1 rotates, and squeezes to be driven by transmission component 2
Component 3 is pressed to move.When moving when the working end of compression assemblies 34 towards the direction close to liquid container 5, working end 4 squeezes liquid and holds
Device 5 enables the volume of liquid container 5 reduce, so that liquid be squeezed out；When the working end of compression assemblies 34 is towards far from liquid container 5
Direction movement when, the volume of liquid container 5 increases, and forms parital vacuum, and then carry out pumpback to liquid.
From the foregoing, it will be observed that passing through the rotation of motor 1, working end 4 can be enabled to act on liquid container 5, by squeezing liquid
Container 5 changes the volume of liquid container 5, to complete the behavior of liquid in driving liquid container 5.The setting of single motor 1
Operated pneumatic valve in the prior art and gas source can be replaced, therefore reduces the volume of equipment, instrument miniaturization is enabled, improves instrument
The portability of device.
As shown in Fig. 2, on the basis of the above embodiments, further, compression assemblies 3 include compression bar arm 301, connector
302 and return unit 303；Working end 4 is provided on compression bar arm 301, connector 302 and return unit 303 are separately positioned on compression bar arm
301 two sides, and connector 302 and return unit 303 are abutted with compression bar arm 301 respectively；Transmission component 2 can be press-connected part
302, to drive compression bar arm 301 to compress or unclamp return unit 303, so that working end 4 is able to carry out reciprocating motion.
Wherein, connector 302 can be idler wheel.
Return unit 303 can be spring.
Specifically, multiple working ends 4 can be set on compression bar arm 301, this makes it possible to the multiple liquid containers 5 of correspondence.
In the present embodiment, in use, when transmission component 2 is press-connected part 302 to drive the compression of compression bar arm 301 multiple
When the part 303 of position, working end 4 squeezes liquid container 5, to reduce the volume of liquid container 5, to squeeze out its internal liquid；When
When transmission component 2 drives compression bar arm 301 to unclamp return unit 303, working end 4 stops squeezing liquid container 5, to stop extrusion liquid
Body.The setting of return unit 303 can enable compression bar arm 301 when the pressure from transmission component 2 reduces or disappears from command of execution pressure
Lever arm 301 resets.
As Figure 1-Figure 4, on the basis of the above embodiments, further, transmission component 2 includes shaft coupling 201, silk
Bar 202, attachment base 203, sliding block 204 and bearing block 205；The both ends of shaft coupling 201 respectively with the power output shaft of motor 1 and
Screw rod 202 connects；Screw rod 202 is threaded through in bearing block 205；Attachment base 203 is mounted on screw rod 202, and attachment base 203 can
Extending direction along screw rod 202 moves back and forth；Attachment base 203 is connect with sliding block 204；One side of the sliding block 204 close to connector 302
It is provided with the protrusion 7 of rake 6 and plane；The one end of rake 6 far from working end 4 is arranged in protrusion 7；Work as connector
302 with rake 6 or protrusion 7 when cooperating, and compression bar arm 301 compresses return unit 303.
Specifically, the upper surface of protrusion 7 is parallel close to the one side of connector 302 with sliding block 204, and protrusion 7 and incline
Inclined portion 6 seamlessly transits.
In the present embodiment, in use, motor 1 drives screw rod 202 to rotate by shaft coupling 201, and bearing block 205 is used
Screw rod 202 is fixed in supporting.When screw rod 202 rotates, attachment base 203 and sliding block 204 do along the extending direction of screw rod 202 past
Multiple movement, when sliding block 204 is moved to, and connector 302 and rake 6 or connector 302 and protrusion 7 is enabled to cooperate, compression bar arm
301 compression return units 303, work at the same time end 4 and squeeze liquid container 5；It is leaned on when sliding block 204 is moved to connector 302 with sliding block 204
When the other positions cooperation of the one side of nearly connector 302, compression bar arm 301 stops compression return unit 303, and return unit 303 is with dynamic pressure
Lever arm 301 resets, and works at the same time end 4 and stops squeezing liquid container 5.Since the protrusion of rake 6 and sliding block 204 are close to connector
302 one side, therefore the setting of rake 6 can be played the role of being press-connected part 302, while can also rise to protrusion 7
To the effect of buffer-oriented, enable connector 302 that can smoothly cooperate with protrusion 7 after rake 6.Screw rod 202 and motor 1
Cooperation can enable motor 1 rotate control it is more accurate.
As shown in figure 4, on the basis of the above embodiments, further, rake 6, protrusion 7 and compression assemblies 3
It is multiple, and quantity is equal.
Specifically, when rake 6 and protrusion 7 are in multiple situations, interval setting and parallel between multiple rakes 6,
Interval setting and parallel between multiple protrusions 7.Multiple connectors 302 can be not provided on the same line, in this way can be in cunning
Block 204 applies different pressure to multiple compression bar arms 301 when moving.The position of multiple working ends 4 can be not arranged in same straight line
On, the liquid container 5 that different location is set can be corresponded to according to the actual situation in this way.
In the present embodiment, in use, multiple rakes 6 are correspondingly arranged with multiple protrusions 7, multiple rakes 6
It is correspondingly arranged with multiple compression assemblies 3, multiple protrusions 7 and multiple compression assemblies 3 are correspondingly arranged.Multiple settings can enable liquid
Body drive corresponds to multiple liquid containers 5, keeps the scope of application of the device wider.
As shown in Figure 1, on the basis of the above embodiments, further, liquid driving device further includes pedestal 8；Transmission
Component 2 further includes guide part 9；Motor 1, compression assemblies 3, transmission component 2 are installed on pedestal 8；The setting of sliding block 204 is being oriented to
On part 9, and sliding block 204 can be moved back and forth along the extending direction of guide part 9.
Wherein, gland 15 is additionally provided on pedestal 8, gland 15 is used to limit the moving range of working end 4.
Gland 15 is detachably connected with pedestal 8, such as is bolted.
Specifically, guide part 9 can be guide rod, guide rod is threaded through in sliding block 204.The extending direction and silk of guide rod
The extending direction of bar 202 is identical.And guide rod can be more, can be improved the stability of the movement of sliding block 204 in this way.
In the present embodiment, in use, sliding block 204 in the process of movement can be along the extending direction of guide part 9
It moves back and forth.The setting of guide part 9 can limit the moving range of sliding block 204, to enable between sliding block 204 and connector 302
What is cooperated is more acurrate.
As depicted in figs. 1 and 2, on the basis of the above embodiments, further, compression assemblies 3 further include shaft 10；Turn
Axis 10 is mounted on pedestal 8；The one end of compression bar arm 301 far from working end 4 and shaft 10 are rotatablely connected.
Wherein, when compression bar arm 301 is multiple, multiple compression bar arms 301 can share a shaft 10.
In the present embodiment, the setting of shaft 10 can further limit the moving range of compression bar arm 301, and be rotatablely connected
Mode can reduce the whole amount of movement of compression bar arm 301, to reduce the volume of device.
As shown in Figure 1, Figure 2, shown in Fig. 3, Fig. 5 and Fig. 6, on the basis of the above embodiments, further, the present invention is implemented
Example provides and additionally provides a kind of liquid sample detection device, and liquid sample detection device includes external diagnosis reagent case 12 and liquid
Driving device；The setting of liquid container 5 is in vitro on diagnostic kit 12.
In the present embodiment, in use, motor 1 is rotated, to drive compression assemblies 3 to move by transmission component 2.
When moving when the working end of compression assemblies 34 towards the direction close to liquid container 5, working end 4 is squeezed on external diagnosis reagent case 12
Liquid container 5, enable the volume of liquid container 5 reduce, so that liquid be squeezed out；When the working end of compression assemblies 34 is towards far from liquid
When the direction movement of body container 5, the volume of liquid container 5 increases, and forms parital vacuum, and then carry out pumpback to liquid.
From the foregoing, it will be observed that passing through the rotation of motor 1, working end 4 can be enabled to act on liquid container 5, by squeezing liquid
Container 5 changes the volume of liquid container 5, to complete the behavior of liquid in driving liquid container 5.The setting of single motor 1
Operated pneumatic valve in the prior art and gas source can be replaced, therefore reduces the volume of equipment, instrument miniaturization is enabled, improves instrument
The portability of device.
As shown in Figure 5 and Figure 6, on the basis of the above embodiments, further, liquid sample detection device further includes control
Device processed；Liquid-level switch 13 and the flow channel for liquids being connected to liquid container 5 14 are provided on external diagnosis reagent case 12；Liquid-level switch
13 are arranged on flow channel for liquids 14；Controller is connect with liquid-level switch 13 and motor 1 respectively；Liquid-level switch 13 is for detecting liquid
The location information of liquid in runner 14, and location information is passed into controller；Controller is used to control the output arteries and veins of motor 1
Punching.
Specifically, multiple flow channel for liquids 14 and multiple liquid-level switches should be correspondingly arranged on when liquid container 5 is multiple
13.It can be detected in this way for the liquid position in different liquids runner 14.
Wherein, the connection between liquid-level switch 13, controller and motor 1 belongs to the prior art, and details are not described herein.
In the present embodiment, in use, when having liquid to pass through inside flow channel for liquids 14, then short circuit is formed.This sets
The accuracy that liquid driving device can be driven by setting detects, and liquid switch believes the position of the liquid in flow channel for liquids 14
Breath is transferred to controller, and whether controller analyzes the information matches with the position that preset motor 1 should drive liquid to flow to.If not
Matching then compensates during driving squeezes liquid next time in controller control motor 1.Such as: when turning for motor 1
Dynamic stepping-in amount reaches setting range, and when working end 4 is not by liquid driven to liquid-level switch 13；Alternatively, the rotation when motor 1 walks
Input is not up to setting range, and working end 4 by liquid driven to liquid-level switch 13 when, it is right that controller controls motor 1
The difference of current stepping-in amount compensates, to ensure the accuracy of liquid flow locations.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement；And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme.
Claims (8)
1. a kind of liquid driving device characterized by comprising motor, transmission component and compression assemblies；
The power output axis connection of the transmission component and the motor；The transmission component is connect with the compression assemblies, with
The working end of the compression assemblies is driven to move towards the direction close to or far from liquid container.
2. liquid driving device according to claim 1, which is characterized in that the compression assemblies include compression bar arm, connection
Part and return unit；
The working end is provided on the compression bar arm, the connector and the return unit are separately positioned on the compression bar arm
Two sides, and the connector and the return unit are abutted with the compression bar arm respectively；The transmission component can squeeze the company
Fitting, to drive the compression bar arm to compress or unclamp the return unit, so that the working end is able to carry out reciprocating motion.
3. liquid driving device according to claim 2, which is characterized in that the transmission component include shaft coupling, screw rod,
Attachment base, sliding block and bearing block；
The both ends of the shaft coupling are connect with the power output shaft of the motor and the screw rod respectively；The screw rod is threaded through institute
It states in bearing block；The attachment base is mounted on the screw rod, and the attachment base can along the screw rod extending direction it is past
Multiple movement；The attachment base is connected with the slide block；
The protrusion that is on one side provided with rake and plane of the sliding block close to the connector；The protrusion is arranged in institute
State the one end of rake far from the working end；
When the connector and the rake or the protrusion cooperate, the compression bar arm compresses the return unit.
4. liquid driving device according to claim 3, which is characterized in that the rake, the protrusion and institute
It is multiple for stating compression assemblies, and quantity is equal.
5. liquid driving device according to claim 3, which is characterized in that the liquid driving device further includes pedestal；
The transmission component further includes guide part；
The motor, the compression assemblies, the transmission component are installed on the pedestal；
The sliding block is arranged on the guide part, and the sliding block can be moved back and forth along the extending direction of the guide part.
6. liquid driving device according to claim 5, which is characterized in that the compression assemblies further include shaft；
The shaft is mounted on the pedestal；The one end of the compression bar arm far from the working end and shaft rotation connect
It connects.
7. a kind of liquid sample detection device, which is characterized in that the liquid sample detection device includes external diagnosis reagent case
And liquid driving device as claimed in any one of claims 1 to 6；
The liquid container is arranged on the external diagnosis reagent case.
8. liquid sample detection device according to claim 7, which is characterized in that the liquid sample detection device also wraps
Include controller；
The flow channel for liquids for being provided with liquid-level switch on the external diagnosis reagent case and being connected to the liquid container；The liquid level
Switch is arranged on the flow channel for liquids；The controller is connect with the liquid-level switch and the motor respectively；
The liquid-level switch is used to detect the location information of liquid in the flow channel for liquids, and the location information is passed to institute
State controller；The controller is used to control the output pulse of the motor.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910643573.9A CN110221088B (en) | 2019-07-17 | 2019-07-17 | Liquid driving device and liquid sample detection equipment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910643573.9A CN110221088B (en) | 2019-07-17 | 2019-07-17 | Liquid driving device and liquid sample detection equipment |
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| CN110221088A true CN110221088A (en) | 2019-09-10 |
| CN110221088B CN110221088B (en) | 2024-02-02 |
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Cited By (1)
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| CN110221088B (en) | 2024-02-02 |
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