CN206408206U - Minisize fluid vacuole pressing mechanism - Google Patents
Minisize fluid vacuole pressing mechanism Download PDFInfo
- Publication number
- CN206408206U CN206408206U CN201621180641.0U CN201621180641U CN206408206U CN 206408206 U CN206408206 U CN 206408206U CN 201621180641 U CN201621180641 U CN 201621180641U CN 206408206 U CN206408206 U CN 206408206U
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- vacuole
- depression bar
- steel ball
- micro
- briquetting
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Abstract
Miniature body fluid steeps pressing mechanism, including framework, the framework is connected and composed by bottom plate, side stand, top-support, and micro-fluidic box support is provided with the middle and lower part of the framework, set in being provided with the micro-fluidic box support and steel ball is provided with the micro-fluidic box of runner, the import of the runner；An elevating mechanism is provided with the top-support, a variety of depression bars moved up and down by its drive are provided with the elevating mechanism, the bottom of the depression bar is provided with the steel ball depression bar that is provided with and can be moved up and down in it and for extruding steel ball in vacuole below the vacuole briquetting that extruding vacuole flows into runner, the vacuole briquetting.Vacuole is squeezed into runner to realize that the fluid of micro-fluidic box is controlled by the utility model by vacuole briquetting, and can be by the sample-adding of reagent, nucleic acid extraction, cleaning, and amplification is effectively combined to be completed in a link, greatly improves detection efficiency.
Description
Technical field
The utility model, which belongs to, is related to a kind of minisize fluid vacuole pressing mechanism.
Background technology
Molecule diagnosis refers to the diagnostic techniques for carrying out clinical detection as biomarker using nucleic acid or protein, is disease
Prediction, diagnose, prevent, treat and lapse to there is provided information and decision-making foundation.Particularly face various sudden infectiousness diseases
Disease, its most economical effective measures are exactly fast and accurately molecule diagnosis.The development of molecule diagnosis is largely examined by molecule
The influence of disconnected automation equipment.Current conventional molecular diagnostic operation is complicated, and process cycle is long.
The content of the invention
The utility model provides the miniature body fluid in a kind of fully automatic molecular diagnostic system for greatly improving detection efficiency
Pressing mechanism is steeped, it can be by the sample-adding of reagent, nucleic acid extraction, cleaning, and amplification is effectively combined to be completed in a link.
The technical solution adopted in the utility model is：
Miniature body fluid steeps pressing mechanism, it is characterised in that：Including framework, the framework is by bottom plate, side stand, top-support
Connect and compose, be provided with the middle and lower part of the framework on micro-fluidic box support, the micro-fluidic box support in being provided with and set runner
Micro-fluidic box, steel ball is provided with the import of the runner；An elevating mechanism, the lift are provided with the top-support
A variety of depression bars moved up and down by its drive are provided with structure, the bottom of the depression bar is provided with the liquid that extruding vacuole flows into runner
Steep the steel ball pressure that is provided with and can be moved up and down in it and for extruding steel ball in vacuole below briquetting, the vacuole briquetting
Bar.Vacuole is squeezed into runner to realize that the fluid of micro-fluidic box is controlled by the utility model by vacuole briquetting, and can be by
The sample-adding of reagent, nucleic acid extraction, cleaning, amplification is effectively combined to be completed in a link, greatly improves detection efficiency.
Further, the elevating mechanism includes a stepper motor being arranged on top-support and the pressure for installing depression bar
It is connected with bridge, the stepper motor on the screw mandrel for being driven by it rotation, the screw mandrel and is set with the silk moved up and down along it
Stem nut, the depression bar frame is with driving its feed screw nut moved up and down to be fixedly connected.
Further, it is provided with the axis of guide, the axis of guide and is set between the top-support and micro-fluidic box support
Guide sleeve, the guide sleeve is fixedly connected with depression bar frame.The utility model ensures that depression bar frame hangs down by the axis of guide and guide sleeve
Directly move up and down.
Further, the guide groove for installing depression bar is offered on the depression bar frame, the upper end of the depression bar is provided with pressure
Bar spring, the Pressure-bar spring is fixed in depression bar frame by spring cup.The utility model causes depression bar phase by Pressure-bar spring
Can be freely movable to depression bar frame, and then vacuole in micro-fluidic box is squeezed into runner by realization successively, realizes micro-fluidic box
Fluid is controlled.
Further, the steel ball depression bar is connected by jump ring with vacuole briquetting, and it is additionally provided with steel ball between vacuole briquetting
Pressure-bar spring, realizes that steel ball depression bar is moved up and down in vacuole briquetting by steel ball Pressure-bar spring.
The beneficial effects of the utility model：The sample-adding of reagent, nucleic acid extraction, cleaning, amplification can be effectively combined
Completed in one link, greatly improve detection efficiency.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model.
Fig. 2 is the enlarged diagram at vacuole extruding of the present utility model.
Fig. 3 a, 3b are vacuole extruding schematic diagrames of the present utility model.
Embodiment
The utility model is further described with reference to specific embodiment, but the utility model not limited to
In these embodiments.One skilled in the art would recognize that the utility model is covered in Claims scope
All alternatives, improvement project and the equivalents potentially included.
Reference picture 1, Fig. 2, miniature body fluid steep pressing mechanism, including framework, and the framework is by bottom plate 5, side stand 3, top
Support 2 is connected and composed, and is provided with the middle and lower part of the framework on micro-fluidic box support 4, the micro-fluidic box support 4 in being provided with
If being provided with steel ball 15 at the micro-fluidic box 16 of runner, the import of the runner；A lift is provided with the top-support 2
A variety of depression bars 6 moved up and down by its drive are provided with structure, the elevating mechanism, the bottom of the depression bar 6 is provided with extruding
Vacuole 14 flows into the vacuole briquetting 7 of runner, and the lower section of the vacuole briquetting 7 is provided with and can moved up and down in it and for extruding
The steel ball depression bar 17 of steel ball 15 in vacuole 14.It is micro- to realize that vacuole 14 is squeezed into runner by the utility model by vacuole briquetting 7
The fluid control of stream control box, and the sample-adding of reagent, nucleic acid extraction, cleaning, amplification can be effectively combined in a link
It is middle to complete, greatly improve detection efficiency.
Elevating mechanism described in the present embodiment includes a stepper motor 1 being arranged on top-support 2 and for installing depression bar 6
Depression bar frame 9, be connected with the stepper motor 1 on the screw mandrel for being driven by it rotation, the screw mandrel and be set with along moving down thereon
Dynamic feed screw nut 12, the depression bar frame 9 is with driving its feed screw nut 12 moved up and down to be fixedly connected.
It is provided with described in the present embodiment between top-support 2 and micro-fluidic box support 4 on the axis of guide 11, the axis of guide 11
Guide sleeve 10 is set with, the guide sleeve 10 is fixedly connected with depression bar frame 9.The utility model passes through the axis of guide 11 and guide sleeve 10
To ensure that depression bar frame 9 is vertically moved.
The guide groove for installing depression bar 6 is offered described in the present embodiment on depression bar frame 9, the upper end of the depression bar 6 is installed
There is Pressure-bar spring 8, the Pressure-bar spring 8 is fixed in depression bar frame 9 by spring cup 13.The utility model passes through Pressure-bar spring 8
Depression bar 6 allow with respect to the freely activity of depression bar frame 9, and then vacuole 14 in micro-fluidic box 16 is squeezed into runner by realization successively,
Realize the fluid control of micro-fluidic box 16.
Steel ball depression bar 17 is connected by jump ring 19 with vacuole briquetting 7 described in the present embodiment, and it also sets between vacuole briquetting 7
There is steel ball Pressure-bar spring 18, realize that steel ball depression bar 17 is moved up and down in vacuole briquetting 7 by steel ball Pressure-bar spring 18.
The utility model drives feed screw nut 12 to be moved down along screw mandrel in use, being rotated by stepper motor 1, so that band
Dynamic pressure bridge 9 is moved downward, during moving downward, in the vacuole 14 that steel ball depression bar 17 will be first fixed in micro-fluidic box 16
Steel ball 15 crush downwards, as shown in Fig. 3 a, move still further below, steel ball depression bar 17 enters in vacuole briquetting 7, under vacuole briquetting 7
Liquid is expressed in the runner in micro-fluidic box 16 by hydraulic fluid bubble 14, as shown in Fig. 3 b.Because depression bar 6 can be in depression bar frame 9
By spring freely activity, wait after the completion of first vacuole extruding, can then continue to extrude other vacuoles successively, wait all liquid
After the completion of bubble extruding, stepper motor 1 returns to initial position, so as to finally realize the fluid control of micro-fluidic box 16.
Claims (5)
1. miniature body fluid steeps pressing mechanism, it is characterised in that：Including framework, the framework is connected by bottom plate, side stand, top-support
Connect and micro-fluidic box support be provided with composition, the middle and lower part of the framework, be provided with the micro-fluidic box support in set runner
Steel ball is provided with micro-fluidic box, the import of the runner；An elevating mechanism, the elevating mechanism are provided with the top-support
On be provided with a variety of by its depression bar for moving up and down of drive, the bottom of the depression bar is provided with the vacuole that extruding vacuole flows into runner
The steel ball depression bar that can be moved up and down in it and for extruding steel ball in vacuole is installed below briquetting, the vacuole briquetting.
2. the miniature body fluid bubble pressing mechanism according to claim 1, it is characterised in that：The elevating mechanism includes a peace
It is connected with stepper motor on top-support and the depression bar frame for installing depression bar, the stepper motor and is driven by it rotation
The feed screw nut moved up and down along it is set with the screw mandrel turned, the screw mandrel, what the depression bar frame was moved up and down with driving it
Feed screw nut is fixedly connected.
3. the miniature body fluid bubble pressing mechanism according to claim 2, it is characterised in that：The top-support with it is micro-fluidic
It is provided between box support on the axis of guide, the axis of guide and is set with guide sleeve, the guide sleeve is fixedly connected with depression bar frame.
4. the miniature body fluid bubble pressing mechanism according to claim 2, it is characterised in that：Use is offered on the depression bar frame
In the guide groove for installing depression bar, the upper end of the depression bar is provided with Pressure-bar spring, and the Pressure-bar spring is fixed on by spring cup
In depression bar frame.
5. the miniature body fluid bubble pressing mechanism according to one of claim 1 ~ 4, it is characterised in that：The steel ball depression bar leads to
Cross jump ring to be connected with vacuole briquetting, it is additionally provided with steel ball Pressure-bar spring between vacuole briquetting, by steel ball Pressure-bar spring come real
Existing steel ball depression bar is moved up and down in vacuole briquetting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621180641.0U CN206408206U (en) | 2016-10-27 | 2016-10-27 | Minisize fluid vacuole pressing mechanism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621180641.0U CN206408206U (en) | 2016-10-27 | 2016-10-27 | Minisize fluid vacuole pressing mechanism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206408206U true CN206408206U (en) | 2017-08-15 |
Family
ID=59548377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621180641.0U Active CN206408206U (en) | 2016-10-27 | 2016-10-27 | Minisize fluid vacuole pressing mechanism |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206408206U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106434282A (en) * | 2016-10-27 | 2017-02-22 | 杭州安杰思生物科技有限公司 | Micro-fluidic vacuole extrusion mechanism |
| CN110221088A (en) * | 2019-07-17 | 2019-09-10 | 东莞博识生物科技有限公司 | Liquid driving device and liquid sample detection device |
| CN114100715A (en) * | 2021-11-22 | 2022-03-01 | 江苏液滴逻辑生物技术有限公司 | Sample injection mode for digital micro-fluidic chip |
-
2016
- 2016-10-27 CN CN201621180641.0U patent/CN206408206U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106434282A (en) * | 2016-10-27 | 2017-02-22 | 杭州安杰思生物科技有限公司 | Micro-fluidic vacuole extrusion mechanism |
| CN110221088A (en) * | 2019-07-17 | 2019-09-10 | 东莞博识生物科技有限公司 | Liquid driving device and liquid sample detection device |
| CN110221088B (en) * | 2019-07-17 | 2024-02-02 | 深圳博识诊断技术有限公司 | Liquid driving device and liquid sample detection equipment |
| CN114100715A (en) * | 2021-11-22 | 2022-03-01 | 江苏液滴逻辑生物技术有限公司 | Sample injection mode for digital micro-fluidic chip |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address |
Address after: Jianggan District Danong Port Road Hangzhou city Zhejiang province 310044 1216 2 Building No. 6 room 607 Patentee after: Hangzhou an reputation Technology Co., Ltd. Address before: Hangzhou City, Zhejiang Province, Zhenhua Road 310030 Xihu District three Town No. 320 building two layer 1 Room 201 Patentee before: HANGZHOU ANJIESI BIOTECHNOLOGY CO., LTD. |
|
| CP03 | Change of name, title or address |