CN204135007U - A kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device - Google Patents
A kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device Download PDFInfo
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- CN204135007U CN204135007U CN201420492446.6U CN201420492446U CN204135007U CN 204135007 U CN204135007 U CN 204135007U CN 201420492446 U CN201420492446 U CN 201420492446U CN 204135007 U CN204135007 U CN 204135007U
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- cleaning
- magneto separate
- guide rail
- motor
- fixedly connected
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Abstract
A kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device, comprising: lifter, cleaning structure, Magneto separate structure, movable block, moving guide rail, pump combines, motor; Described lifter is fixedly connected with cleaning structure, and described Magneto separate structure is positioned at the side of movable block, and described moving guide rail is positioned at the below of movable block, and described pump is combined through flexible pipe and is connected with cleaning structure.The utility model provides a kind of structure simply, and convenient operation is with low cost, shortens the Magnetic Isolation time, improves separating effect, controls precisely and energy and other chemiluminescence immunoassay detection parts matching used chemiluminescence immunoassay Magneto separate cleaning device device.
Description
Technical field
The utility model relates to a kind of new type medical equipment, particularly relates to a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device.
Background technology
Chemiluminescence immunoassay technology, because its degree of accuracy is high, easy to operate, is widely applied in field of biological detection.Microwell plate Reusability in traditional board-like chemiluminescence immunoassay technology, exists and pollutes; Board-like is generally wide variety of glow-type, and photon collection efficiency is low.Fully-automated synthesis instrument collection incubation, Magneto separate cleaning detects and one, for each class sample, its optimal hatching reagent and incubation conditions all can be different, and traditional loading device is through long-term use, pin group there will be error in the control of application of sample amount, cause experimental result to be forbidden, and the maintenance of pin group is complicated, and the most build of fully-automated synthesis instrument is excessive, cost is higher, is not suitable for using in laboratory or small sample amount hospital.
Moreover artificial magnetic separation controls inaccuracy, easily goes out experimental error.Manual cleaning 3-6 time, wastes time and energy, and easily occurs the situation damaging Magnetic bead sample.All adopt the reaction cup cup platform of turntable form in prior art, be limited to the shape of turntable, setting-out can cause confusion, pin group limited amount, and pin group is easily contaminated, requires higher, easily break down to pin shelving guide rail.In addition, in existing magnetic separation technique, the Time Dependent of Magnetic Isolation is in magnetic field intensity, cannot shorten.
Utility model content
Problem to be solved, the utility model provides a kind of structure simple, convenient operation, with low cost, shorten the Magnetic Isolation time, improve separating effect, control precisely and energy and other chemiluminescence immunoassay detection parts matching used chemiluminescence immunoassay Magneto separate cleaning device device.
Technical scheme: a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device, comprising: lifter, cleaning structure, Magneto separate structure, movable block, moving guide rail, pump combines, motor; Described lifter is fixedly connected with cleaning structure, and described Magneto separate structure is positioned at the side of movable block, and described moving guide rail is positioned at the below of movable block, and described pump is combined through flexible pipe and is connected with cleaning structure.
Further technical scheme, described lifter comprises elevator shelves, guide rail, guide rail slide block, take-up housing, drive mechanism, driving block, and described drive mechanism comprises wheel shaft, motor shaft, the first synchronizing wheel, the second synchronizing wheel, belt;
Described elevator shelves top and bottom install wheel shaft and motor shaft respectively, described wheel shaft connects the first synchronizing wheel, described motor shaft connects the second synchronizing wheel, described belt sleeve is on the first synchronizing wheel and the second synchronizing wheel, described guide rail is fixedly connected on elevator shelves, described guide rail slide block is placed on guide rail, and described take-up housing to be fixed on belt and to be fixedly connected with guide rail slide block;
Described motor comprises the first motor, the second motor, the 3rd motor, the 4th motor;
Described cleaning structure comprises: cleaning vertical rod, cleaning needle base, needle tubing lid, cleaning needle, described cleaning vertical rod is fixedly connected with driving block by iron stator, described cleaning needle base one end is fixedly connected with cleaning vertical rod, and the other end is provided with cleaning needle, and described needle tubing lid is placed in the top of cleaning needle base;
Described Magneto separate structure comprises magnet shaft bar, and magnetic beats shaft bar, magnet bar, small magnet, and magnetic makes bar, and the end of described magnet bar connects small magnet, and described small magnet and magnetic beat the side that bar is all positioned at movable block;
Described movable block inside is provided with reaction cup groove, and there is an opening described movable block side;
Described moving guide rail comprises movable base, base contiguous block, screw mandrel, slide block, track, described movable base is positioned at the below of movable block and is fixedly connected with, described movable base is stuck on screw mandrel, described base contiguous block is fixedly connected on movable base both sides, and described slide block to be positioned at below base contiguous block and to be fixedly connected with, and described slide block is placed on track.
Further technical scheme, described cleaning needle comprises minute hand and hour hand.
Further technical scheme, described screw mandrel one end is also provided with electric machine support.
Further technical scheme, first motor is positioned at the elevator shelves back side and is fixedly connected with elevator shelves, second motor to be positioned on electric machine support and to be connected with screw mandrel, 3rd motor to be positioned on magnet shaft bar and to be connected with magnet bar, and the 4th motor is positioned at magnetic and beats on shaft bar and make bar with magnetic and be connected.
Further technical scheme, described pump combination comprises pump and pump bracket, and pump is fixedly connected with pump bracket, and described pump is connected with cleaning needle by flexible pipe.
Further technical scheme, described Magneto separate structure is also provided with magnetic and plays pole spacing circle, and described magnetic is played pole spacing circle and is fixedly connected with magnet shaft bar.
Further technical scheme, described moving guide rail is also provided with guide rail catch, and described guide rail catch is fixed on the back side of movable block.
Further technical scheme, described lifter is also provided with cleaning catch, and described cleaning catch is fixed on driving block.
beneficial effect:
A kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device, the reaction tube of tubular type is all disposable, not easily contaminated, adopts position, side magnetic separation technique, and magnetic plays bar design in addition, makes the Magnetic Isolation time short.A kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device volume that the technical program provides is little, structure is simple, stable performance, cleaning, good separating effect, control precisely and can and other chemiluminescence immunoassay detection parts matching used.。
1, reaction cup is placed in movable block inside, mobile more steady, contrast traditional spinning stage design, do not need mechanical arm to do grasping movement just can accomplish magnetic separation and be separated, decrease the probability of sample contamination, movable block design simultaneously avoids the shortcoming that reaction cup is put in turntable circulation, is not easy the situation occurring mistaking sample.Movable block designs, can the row's of supporting the use formula reaction cup rim of a cup holder, reduces operating procedure, saves time.
2, the Activities Design of Magneto separate structure can make small magnet be reduced to minimum on circuit impact, reduce the magnetized probability of metal parts, increase the service life, magnetic separation time controling is accurate, in addition, small magnet acts on reaction cup side, makes magnetic bead in magnetic separation cleaning process be attached to reaction cup sidewall, avoids pin group to damage the object of enrichment on magnetic bead.
3,magnetic plays bar continuous drumming reaction cup in magnetic separation process, and periphery of magnetic beads reactant liquor is exchanged frequent, improve the speed of magnetic particle aggregation, shorten the time of Magnetic Isolation, magnetic separation contact area increases, and contributes to the accurate of experimental data; There is an opening movable block side, directly can beat reaction cup, and opening can connect detecting instrument, completes detection.
4, cleaning needle is divided into minute hand and hour hand pin group to comprise at least one group leader's hour hand, minute hand is for drawing liquid in reaction cup, stretch in reaction cup, hour hand does not stretch in reaction cup, minute hand is utilized to reach drainage effect, for supplementing new liquid in reaction cup, the design of long and short hands can reach the object thoroughly drawing waste liquid, also can avoid cleaning liquid and feed liquor syringe needle contaminated.
5, electric machine support plays and supports fixing effect, and motor and other mechanical parts are separated into relatively independent region, when certain parts of driven by motor machinery rotate, vibrations is dropped to very low level.
6, the position arrangement of motor is comparatively near apart from respective control assembly, and convenient wiring and maintenance, save space, reduce the wastage.
7, pump produces pressure, and for passing in and out the management of liquid, pump is together with pump bracket, and the vibrations produced in energy minimizing work, reduced the impact of Magneto separate by machinery, flexible pipe suppleness is high, is applicable to wiring.
8, magnetic is played pole spacing and is enclosed the effect limiting position, magnetic can be assisted to make bar and knock motion.
9, guide rail catch plays position-limiting action.
10, lifter is also provided with cleaning catch, prevents lifter from exceeding predetermined movement scope, affects machine and uses.
Accompanying drawing explanation
Fig. 1 is the three-dimensional structure diagram of a kind of tube-type chemical electrochemiluminescent immunoassay of the utility model Magneto separate cleaning device;
Fig. 2 is the riser structure figure of a kind of tube-type chemical electrochemiluminescent immunoassay of the utility model Magneto separate cleaning device;
Fig. 3 is the side view of a kind of tube-type chemical electrochemiluminescent immunoassay of the utility model Magneto separate cleaning device;
Fig. 4 is moving guide rail structure chart in a kind of tube-type chemical electrochemiluminescent immunoassay of the utility model Magneto separate cleaning device;
Fig. 5 is pump combination assumption diagram in a kind of tube-type chemical electrochemiluminescent immunoassay of the utility model Magneto separate cleaning device.
Specific embodiment
As shown in Fig. 1 to 5, a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device, comprising: lifter 1, cleaning structure 2, Magneto separate structure 3, movable block 4, moving guide rail 5, pump combination 6, motor 7; Described lifter 1 is fixedly connected with cleaning structure 2, and described Magneto separate structure 3 is positioned at the side of movable block 4, and described moving guide rail 5 is positioned at the below of movable block 4, and described pump combination 6 is connected with cleaning structure 2 by flexible pipe.
Described lifter 1 comprises elevator shelves 1-1, guide rail 1-2, guide rail slide block 1-3, take-up housing 1-4, drive mechanism 1-5, driving block 1-6, described drive mechanism 1-5 comprises wheel shaft (1-5-1), motor shaft 1-5-2, first synchronizing wheel 1-5-3, the second synchronizing wheel 1-5-4, belt 1-5-5;
Described elevator shelves top and bottom install wheel shaft 1-5-1 and motor shaft 1-5-2 respectively, described wheel shaft 1-5-1 connects the first synchronizing wheel 1-5-3, described motor shaft 1-5-2 connects the second synchronizing wheel 1-5-4, described belt 1-5-5 is enclosed within the first synchronizing wheel 1-5-3 and the second synchronizing wheel 1-5-4, described guide rail 1-2 is fixedly connected on elevator shelves 1-1, described guide rail slide block 1-3 is placed on guide rail 1-2, and described take-up housing 1-4 to be fixed on belt 1-5-5 and to be fixedly connected with guide rail slide block 1-3;
Described motor comprises the first motor 7-1, the second motor 7-2, the 3rd motor 7-3, the 4th motor 7-4;
Described cleaning structure 2 comprises: cleaning vertical rod 2-1, cleaning needle base 2-2, needle tubing lid 2-3, cleaning needle 2-4, described cleaning vertical rod 2-1 is fixedly connected with driving block 1-6 by iron stator, described cleaning needle base 2-2 one end is fixedly connected with cleaning vertical rod 2-1, and the other end is provided with cleaning needle 2-4, and described needle tubing lid 2-3 is placed in directly over cleaning needle base 2-2;
Described Magneto separate structure 3 comprises magnet shaft bar 3-1, and magnetic beats shaft bar 3-2, magnet bar 3-3, small magnet 3-4, magnetic beats bar 3-5, and the end of described magnet bar 3-3 connects small magnet 3-4, and described small magnet 3-4 and magnetic beat the side that bar 3-3 is all positioned at movable block 4;
Described movable block 4 inside is provided with reaction cup groove 4-2, and there is an opening described movable block 4 side;
Described moving guide rail 5 comprises movable base 5-1, base contiguous block 5-2, screw mandrel 5-3, slide block 5-4, track 5-5, described movable base 5-1 is positioned at the below of movable block 4 and is fixedly connected with, described movable base 5-1 is stuck on screw mandrel 5-3, described base contiguous block 5-2 is fixedly connected on movable base 5-1 both sides, and described slide block 5-4 to be positioned at below base contiguous block 5-2 and to be fixedly connected with, and described slide block 5-4 is placed on track 5-5.
Described cleaning needle 2-4 comprises minute hand and hour hand.
Described screw mandrel 5-3 one end is also provided with electric machine support 8.
First motor 7-1 is positioned at the elevator shelves 1-1 back side and is fixedly connected with elevator shelves 1-1, second motor 7-2 to be positioned on electric machine support 8 and to be connected with screw mandrel 5-3,3rd motor 7-3 to be positioned on magnet shaft bar 3-1 and to be connected with magnet bar 3-3, and the 4th motor 7-4 is positioned at magnetic and beats on shaft bar 3-2 and beat bar 3-5 with magnetic and be connected.
Described pump combination 6 comprises pump 6-1 and pump bracket 6-2, and pump 6-1 is fixedly connected with pump bracket 6-2, and described pump 6-1 is connected with cleaning needle 2-4 by flexible pipe.
Described Magneto separate structure 3 is also provided with magnetic and plays pole spacing circle 9, and described magnetic is played pole spacing circle 9 and is fixedly connected with magnet shaft bar 3-1.
Described moving guide rail 5 is also provided with guide rail catch 5-6, and described guide rail catch 5-6 is fixed on the back side of movable block 4.
Described lifter 1 is also provided with cleaning catch 1-7, and described cleaning catch 1-7 is fixed on driving block 1-6.
Workflow: reaction cup is put into movable block 4 reaction cup groove 4-2, under second motor 7-2 drives, move along guide rail 5-5, reach operating position, 3rd motor 7-3 is with moving magnet bar 3-3 to rotate, the small magnet 3-4 of its end rotates and starts working to movable block 4 reaction cup groove 4-2 relevant position, simultaneously the 4th motor 7-4 drives magnetic to beat bar 3-5 to movable block 4 reaction cup groove 4-2 relevant position to start working, its end is drumming reaction cup repeatedly, magnetic is played pole spacing circle 9 and is played the effect limiting position, magnetic can be assisted to make bar and knock motion.After Magneto separate process terminates, magnet bar 3-3, magnetic are beaten bar 3-5 and are playbacked.Movable block 4 is under the second motor 7-2 drives, and arrive cleaning positions along guide rail 5-5, this position is positioned at below cleaning needle 2-4.Cleaning needle 2-4 original state is high-order.First motor 7-1 drives drive mechanism 1-5 motion, and then drive cleaning structure 2 to move downward, cleaning needle 2-4 minute hand arrives bottom reaction cup, start working under pump 6-1 effect, minute hand abstraction reaction cup content, hour hand does not contact with reaction cup, utilizes minute hand to form drainage, cleaning fluid enters in reaction cup, repeatedly terminates to cleaning process.Pin group resets, and movable block resets.
Claims (9)
1. a tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device, is characterized in that, comprising: lifter (1), cleaning structure (2), Magneto separate structure (3), movable block (4), moving guide rail (5), pump combination (6), motor (7); Described lifter (1) is fixedly connected with cleaning structure (2), described Magneto separate structure (3) is positioned at the side of movable block (4), described moving guide rail (5) is positioned at the below of movable block (4), and described pump combination (6) is connected with cleaning structure (2) by flexible pipe.
2. a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device according to claim 1, it is characterized in that, described lifter (1) comprises elevator shelves (1-1), guide rail (1-2), guide rail slide block (1-3), take-up housing (1-4), drive mechanism (1-5), the drive mechanism (1-5) described in driving block (1-6) comprises wheel shaft (1-5-1), motor shaft (1-5-2), first synchronizing wheel (1-5-3), the second synchronizing wheel (1-5-4), belt (1-5-5);
Described elevator shelves top and bottom install wheel shaft (1-5-1) and motor shaft (1-5-2) respectively, described wheel shaft (1-5-1) connects the first synchronizing wheel (1-5-3), described motor shaft (1-5-2) connects the second synchronizing wheel (1-5-4), described belt (1-5-5) is enclosed within the first synchronizing wheel (1-5-3) and the second synchronizing wheel (1-5-4), described guide rail (1-2) is fixedly connected on elevator shelves (1-1), described guide rail slide block (1-3) is placed on guide rail (1-2), described take-up housing (1-4) is fixed on belt (1-5-5) and goes up and be fixedly connected with guide rail slide block (1-3),
Described motor comprises the first motor (7-1), the second motor (7-2), the 3rd motor (7-3), the 4th motor (7-4);
Described cleaning structure (2) comprising: cleaning vertical rod (2-1), cleaning needle base (2-2), needle tubing lid (2-3), cleaning needle (2-4), described cleaning vertical rod (2-1) is fixedly connected with driving block (1-6) by iron stator, described cleaning needle base (2-2) one end is fixedly connected with cleaning vertical rod (2-1), and the other end is provided with cleaning needle (2-4), and described needle tubing lid (2-3) is placed in directly over cleaning needle base (2-2);
Described Magneto separate structure (3) comprises magnet shaft bar (3-1), magnetic beats shaft bar (3-2), magnet bar (3-3), small magnet (3-4), magnetic makes bar (3-5), the end of described magnet bar (3-3) connects small magnet (3-4), and described small magnet (3-4) and magnetic beat the side that bar (3-3) is all positioned at movable block (4);
Described movable block (4) inside is provided with reaction cup groove (4-2), has an opening in movable block (4) side;
Described moving guide rail (5) comprises movable base (5-1), base contiguous block (5-2), screw mandrel (5-3), slide block (5-4), track (5-5), described movable base (5-1) is positioned at the below of movable block (4) and is fixedly connected with, described movable base (5-1) is stuck on screw mandrel (5-3), described base contiguous block (5-2) is fixedly connected on movable base (5-1) both sides, described slide block (5-4) is positioned at base contiguous block (5-2) below and is fixedly connected with, and described slide block (5-4) is placed on track (5-5).
3. a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device according to claim 2, it is characterized in that, described cleaning needle (2-4) comprises minute hand and hour hand.
4. a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device according to claim 2, it is characterized in that, described screw mandrel (5-3) one end is also provided with electric machine support (8).
5. a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device according to claim 1,2 or 4, it is characterized in that, first motor (7-1) is positioned at elevator shelves (1-1) back side and is fixedly connected with elevator shelves (1-1), second motor (7-2) is positioned at electric machine support (8) and goes up and be connected with screw mandrel (5-3), it is upper and be connected with magnet bar (3-3) that 3rd motor (7-3) is positioned at magnet shaft bar (3-1), and the 4th motor (7-4) is positioned at magnetic and beats shaft bar (3-2) and go up and make bar (3-5) with magnetic and be connected.
6. a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device according to claim 1, it is characterized in that, described pump combination (6) comprises pump (6-1) and pump bracket (6-2), pump (6-1) is fixedly connected with pump bracket (6-2), and described pump (6-1) is connected with cleaning needle (2-4) by flexible pipe.
7. a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device according to claim 1 and 2, it is characterized in that, described Magneto separate structure (3) is also provided with magnetic and plays pole spacing circle (9), and described magnetic is played pole spacing circle (9) and is fixedly connected with magnet shaft bar (3-1).
8. a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device according to claim 1 and 2, it is characterized in that, described moving guide rail (5) is also provided with guide rail catch (5-6), and described guide rail catch (5-6) is fixed on the back side of movable block (4).
9. a kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device according to claim 1 and 2, is characterized in that, described lifter (1) is also provided with cleaning catch (1-7), and described cleaning catch (1-7) is fixed on driving block (1-6).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420492446.6U CN204135007U (en) | 2014-08-29 | 2014-08-29 | A kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420492446.6U CN204135007U (en) | 2014-08-29 | 2014-08-29 | A kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device |
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| Publication Number | Publication Date |
|---|---|
| CN204135007U true CN204135007U (en) | 2015-02-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420492446.6U Withdrawn - After Issue CN204135007U (en) | 2014-08-29 | 2014-08-29 | A kind of tube-type chemical electrochemiluminescent immunoassay Magneto separate cleaning device |
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| Country | Link |
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| CN (1) | CN204135007U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104324921A (en) * | 2014-08-29 | 2015-02-04 | 南京诺尔曼生物技术有限公司 | Tubular chemical luminescence immunity magnetic separation and cleaning device |
| CN109174853A (en) * | 2018-10-24 | 2019-01-11 | 嘉兴凯实生物科技有限公司 | A kind of magnetic separating device with service sink |
-
2014
- 2014-08-29 CN CN201420492446.6U patent/CN204135007U/en not_active Withdrawn - After Issue
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104324921A (en) * | 2014-08-29 | 2015-02-04 | 南京诺尔曼生物技术有限公司 | Tubular chemical luminescence immunity magnetic separation and cleaning device |
| CN109174853A (en) * | 2018-10-24 | 2019-01-11 | 嘉兴凯实生物科技有限公司 | A kind of magnetic separating device with service sink |
| CN109174853B (en) * | 2018-10-24 | 2023-10-17 | 嘉兴凯实生物科技股份有限公司 | Magnetic separation device with cleaning pool |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20150204 Effective date of abandoning: 20160615 |
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| C25 | Abandonment of patent right or utility model to avoid double patenting |