CN110201063A - A kind of Chinese medicine composition for treating liver function detraction - Google Patents

A kind of Chinese medicine composition for treating liver function detraction Download PDF

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CN110201063A
CN110201063A CN201910600269.6A CN201910600269A CN110201063A CN 110201063 A CN110201063 A CN 110201063A CN 201910600269 A CN201910600269 A CN 201910600269A CN 110201063 A CN110201063 A CN 110201063A
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parts
detraction
liver function
chinese medicine
weight
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姜鹏凌
姜奕轲
叶喜德
彭玲珍
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    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

A kind of Chinese medicine composition for treating liver function detraction, is made: 10-20 parts of pennywort, 10-20 parts of field pennycress, 10-15 parts of Radix Salviae Miltiorrhizae, 5-10 parts of Bupleurum Chinese, 5-10 parts of wrinkled giant hyssop, 10-15 parts of HERBA CIRSII, 10-15 parts of capillary wormwood, 10-15 parts of cordate houttuynia, 5-10 parts of radix gentianae, 10-15 parts of Asiatic plantain of forming for following parts by weight.

Description

A kind of Chinese medicine composition for treating liver function detraction
Technical field
The present invention relates to a kind of Chinese medicine compositions for treating liver function detraction, belong to drug field.
Background technique
Chronic hepatitis B is a kind of very common and has communicable disease, and further it is hard to will lead to liver for development Change, liver cancer, seriously affect the physical and mental health of people, brings huge financial burden to personal and society.It is directed to chronic at present Liver does not have specific drug, and doctor trained in Western medicine antiviral therapy slows down the development of the state of an illness to a certain extent, but antiviral agent is expensive, easy Drug resistance, easy to recur after drug withdrawal and side effect etc. also bring biggish difficulty to clinical treatment, to the heavy economy of patient's back And mental burden.It facts have proved that Chinese medicine has certain antivirus action.
CN102100775A discloses a kind of pharmaceutical composition of hepatitis virus resisting, it is the raw material matched by following weight The preparation that medicine is prepared: 10~200 parts of polygonum cuspidate, 10~360 parts of oriental wormwood, 10~300 parts of oldenlandia diffusa, cape jasmine 10~200 Part, 10~200 parts of Lygodium japonicum.It is used to treat chronic hepatitis, cirrhosis, and drug effect is clear, and is substantially better than Isodose and places an order The medicinal substances extract solely used.
CN101301451A discloses the Chinese medicine medicine for a kind for the treatment of both manifestation and root cause of disease, without side-effects, cheap treatment hepatopathy Object.Its made of following component (dosage is parts by weight): Canton love-pea vine 30-60, rock cypress branch 10-30, hypericum japonicum 10-30, polygonum cuspidate 10-30, rabdosia lophanthide 10-30, white backleaf mallotus root 30-90, Artemisia capillaris 9-45, Radix Isatidis 9-15, folium isatidis 10-15, oldenlandia diffusa 20-40, cape jasmine 10-15, Radix Curcumae 5-10, fructus polygoni orientalis 10-15, downy rosemyrtle root 15-30, Prunella vulgaris 6-15, Radix Salviae Miltiorrhizae 10-15, peach kernel 5-10, alkanet 3-9, bluish dogbane 6-9, pennywort 10-30, Radix Astragali 10-15, serissa serissoide 9-30, Japanese ardisia 10-30, kalimeris are green 9-30, creeping oxalis 6-30, kuh-seng 3-9, stringy stonecrop 15-30, Lysimachia christinae Hance 10-30, Verbena officinalis 15-30, cape jasmine root 10-30； Traditional Chinese herbal decoction or powder is made in above-mentioned each component according to a conventional method.There is the drug soothing liver-qi stagnation, clearing heat and promoting diuresis, promoting blood circulation to stop Blood, eliminating stasis to subdue swelling, righting Li Shui, the function of enhancing immunity of organisms, can be used for virus hepatitis, and icteric, non-icteric pass The treatment of metachromia hepatitis, it is also effective in cure for chronic persistent active hepatitis, cirrhosis and cirrhotic ascites etc..
Summary of the invention
The object of the present invention is to provide a kind of Chinese traditional medicine compositions of efficient, quick-acting, long-acting, less toxic treatment liver function detraction Object.
It is achieved through the following technical solutions:
A kind of Chinese medicine composition for treating liver function detraction, is made of forming for following parts by weight: 10-20 parts of pennywort, 10-20 parts of field pennycress, 10-15 parts of Radix Salviae Miltiorrhizae, 5-10 parts of Bupleurum Chinese, 5-10 parts of wrinkled giant hyssop, 10-15 parts of HERBA CIRSII, capillary wormwood 10-15 Part, 10-15 parts of cordate houttuynia, 5-10 parts of radix gentianae, 10-15 parts of Asiatic plantain.
Preferably, pennywort 12-18 parts, 12-18 parts of field pennycress, 12-14 parts of Radix Salviae Miltiorrhizae, 6-8 parts of Bupleurum Chinese, 7-9 parts of wrinkled giant hyssop, 11-14 parts of HERBA CIRSII, 12-14 parts of capillary wormwood, 13-15 parts of cordate houttuynia, 6-9 parts of radix gentianae, 12-14 parts of Asiatic plantain.
Further, 16 parts of pennywort, 14 parts of field pennycress, 13 parts of Radix Salviae Miltiorrhizae, 7 parts of Bupleurum Chinese, 8 parts of wrinkled giant hyssop, 13 parts of HERBA CIRSII, 13 parts of capillary wormwood, 14 parts of cordate houttuynia, 7 parts of radix gentianae, 13 parts of Asiatic plantain.
Treat liver function detraction traditional Chinese herbal decoction the preparation method comprises the following steps: weighing Chinese medicine by above-mentioned parts by weight is put into decoction vessel In tool, water is added, amount of water impregnates half an hour, be sufficiently humidified so as to medicinal material to be more than powder 2-3cm for degree, abundant with sharp decoction It is fried, it after being boiled with very hot oven, uses instead to decoct with slow fire 20 minutes and stops, filtering off the dregs of a decoction, take decoction.
Treat the Chinese medicine low sugar electuary of liver function detraction the preparation method comprises the following steps: above-mentioned decoction is concentrated, be put into low sugar auxiliary material, It stirs, is dried in vacuo to get low sugar electuary.
Through Clinical and experimental study, we to hepatitis B and other virus hepatitis, Alcoholic and nonalcoholic fatty liver Liver function detraction especially often has apparent therapeutic effect to the multiple of ALT and AST.Effective percentage is 87%, and obvious effective rate 72% has Efficiently, quick-acting, long-acting, less toxic features.
Specific embodiment
It is limited below with reference to specific embodiment technical solution of the present invention is further, but claimed Range is not only limited to made description.
Embodiment 1: a kind of pharmaceutical composition of hepatitis virus resisting, the parts by weight of each component are as follows: 16 parts of pennywort, field pennycress 14 parts, 13 parts of Radix Salviae Miltiorrhizae, 7 parts of Bupleurum Chinese, 8 parts of wrinkled giant hyssop, 13 parts of HERBA CIRSII, 13 parts of capillary wormwood, 14 parts of cordate houttuynia, 7 parts of radix gentianae, vehicle First careless 13 parts.
Treat liver function detraction traditional Chinese herbal decoction the preparation method comprises the following steps: weighing Chinese medicine by above-mentioned parts by weight is put into decoction vessel In tool, water is added, amount of water impregnates half an hour, be sufficiently humidified so as to medicinal material to be more than powder 2-3cm for degree, abundant with sharp decoction It is fried, it after being boiled with very hot oven, uses instead to decoct with slow fire 20 minutes and stops, filtering off the dregs of a decoction, take decoction.
Treat the Chinese medicine low sugar electuary of liver function detraction the preparation method comprises the following steps: above-mentioned decoction is concentrated, be put into low sugar auxiliary material, It stirs, is dried in vacuo to get low sugar granule granule.
Typical case is as follows:
Patient's week so-and-so, male, 46 years old, Jiangxi people from Yugan, the first visit when March in 2003 of the morning 9 on the 19th.
Patient medical history:, in the first half of the year in 1992 because of fatigue and weak, poor abdominal distension of receiving is seen a doctor for it, is diagnosed as " virus hepatitis, second Type, chronic mild ".Through treating half a year, symptom disappears, and liver function is multiple normal.The first half of the year in 1999 causes to recur because drinking to stay up late, and controls Treatment exceedes year symptom and mitigates, and liver function recovery is normally discontinued afterwards, but hepatitis B two is still " great three positive " to half prompt.Phase in the Spring Festival in 2003 Between because of dinner party fatigue, the careless state of an illness of diet is again repeatedly.It is toward First Affiliated Hospital Of Nanchang University's diagnosis and treatment, diagnosis are as follows: " hepatitis B is slow Property moderate ".It is recommended that taking " lamivudine " antiviral therapy for a long time, it is reluctant Long-term taking medicine, carrys out my door on March 19th, 2003 It examines and traditional Chinese medicine is required to treat.
It is as follows in relation to survey report: hepatitis B two is negative to half HbsAg positive HbsAb feminine gender HbeAg positive HbeAb HbcAb positive HBV-DNA5.6 × 1,0^7 I U/ml liver function ALT656lU/L (< 40lU/L) AST529lU/L (< 40lU/L) ALP149lU/L (< 135lU/L) GGT197lU/L (< 45lU/L) quarter examines: sallow complexion is dim stagnant, and body is thin and weak, tired mind, mouth Hardship receives difference, gastral cavity ruffian abdominal distension, irritable, defecates not well；The light red yellow and greasy fur center of tongue nature is thick, veins string band number.Card belongs to damp and hot and accumulates poison, Liver and gallbladder, which are lost, dredges.
Patient takes low sugar granule granule of the invention (10 grams/packet) 2 packet every time, 3 times a day.After continuously taking 2 weeks, essence Mind improves, and bitter taste disappears, and poor abdominal distension of receiving is substantially reduced, looks into liver function: ALT229lU/L (< 40lU/L) AST206lU/L (< 40lU/L)ALPlU/L132(<135lU/L)GGT205lU/L(<45lU/L)。
It follows the doctor's advice and takes low sugar granule granule of the invention again 3 weeks, amount is the same.Further consultation after 3 weeks, the bright profit of complexion, spiritual food intake Good, liver function is remaining normal in addition to GGT 186lU/L (< 45lU/L).
It continues thereafter with and takes low sugar granule granule 2 packet every time, 2 times a day.It is normal that liver function is checked after 3 months, is had rosy cheeks, Spiritual food intake is all good, weight gain.
In by the end of March, 2004 to, liver function is normal, HBV-DNA < 1 × 10 for medication3IU/ml, HbeAg turn out cloudy, withdrawal observation. In December, 2004 check: HBV-DNA < 1 × 103IU/ml, HbeAg feminine gender HbeAb are positive, serological conversion.Follow-up so far, hepatitis B Blood serum designated object disappears, and liver function is normal.

Claims (5)

1. a kind of Chinese medicine composition for treating liver function detraction, which is characterized in that be made of forming for following parts by weight: pennywort 10-20 parts, 10-20 parts of field pennycress, 10-15 parts of Radix Salviae Miltiorrhizae, 5-10 parts of Bupleurum Chinese, 5-10 parts of wrinkled giant hyssop, 10-15 parts of HERBA CIRSII, continuous mattress 10-15 parts old, 10-15 parts of cordate houttuynia, 5-10 parts of radix gentianae, 10-15 parts of Asiatic plantain.
2. the Chinese medicine composition for the treatment of liver function detraction as described in claim 1, which is characterized in that by the group of following parts by weight At being made: 12-18 parts of pennywort, 12-18 parts of field pennycress, 12-14 parts of Radix Salviae Miltiorrhizae, 6-8 parts of Bupleurum Chinese, 7-9 parts of wrinkled giant hyssop, HERBA CIRSII 11-14 parts, 12-14 parts of capillary wormwood, 13-15 parts of cordate houttuynia, 6-9 parts of radix gentianae, 12-14 parts of Asiatic plantain.
3. the Chinese medicine composition for the treatment of liver function detraction as claimed in claim 2, which is characterized in that by the group of following parts by weight At being made: the parts by weight of each component are as follows: 16 parts of pennywort, 14 parts of field pennycress, 13 parts of Radix Salviae Miltiorrhizae, 7 parts of Bupleurum Chinese, 8 parts of wrinkled giant hyssop, field thistle Careless 13 parts, 13 parts of capillary wormwood, 14 parts of cordate houttuynia, 7 parts of radix gentianae, 13 parts of Asiatic plantain.
4. a kind of preparation method for the traditional Chinese herbal decoction for treating liver function detraction, which is characterized in that press claim 1-3 any one The parts by weight weigh Chinese medicine and are put into drug-decocting appliance, and water is added, and amount of water impregnates half to be more than powder 2-3cm for degree Hour, it is sufficiently humidified so as to medicinal material, it is sufficiently fried with sharp decoction, after being boiled with very hot oven, uses instead and decoct with slow fire stopping in 20 minutes, filter off The dregs of a decoction take decoction.
5. a kind of preparation method for the Chinese medicine low sugar electuary for treating liver function detraction, which is characterized in that by the soup in claim 4 Agent concentration, is put into low sugar auxiliary material, stirs, and is dried in vacuo to get low sugar granule granule.
CN201910600269.6A 2019-07-04 2019-07-04 A kind of Chinese medicine composition for treating liver function detraction Pending CN110201063A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1078905A (en) * 1993-04-02 1993-12-01 淄博市第一医院 A kind of medicine for external use for the treatment of hepatopathy
CN1236623A (en) * 1998-05-21 1999-12-01 姜鹏凌 Medicine for treating hepatitis B
CN1951425A (en) * 2006-10-08 2007-04-25 刘家友 Chinese medicine for treating liver disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1078905A (en) * 1993-04-02 1993-12-01 淄博市第一医院 A kind of medicine for external use for the treatment of hepatopathy
CN1236623A (en) * 1998-05-21 1999-12-01 姜鹏凌 Medicine for treating hepatitis B
CN1951425A (en) * 2006-10-08 2007-04-25 刘家友 Chinese medicine for treating liver disease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
姜鹏凌、李富国: ""乙肝复康"治疗乙型肝炎230例疗效分析", 《实用中西医结合临床》 *
汪毅主编: "《黔本草》", 31 March 2015 *

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