CN110168104A - 使用纳米孔表征分析物的方法和系统 - Google Patents

使用纳米孔表征分析物的方法和系统 Download PDF

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Publication number
CN110168104A
CN110168104A CN201780083105.XA CN201780083105A CN110168104A CN 110168104 A CN110168104 A CN 110168104A CN 201780083105 A CN201780083105 A CN 201780083105A CN 110168104 A CN110168104 A CN 110168104A
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pore
polynucleotide
nano
stranded
polynucleotides
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Chinese (zh)
Inventor
詹姆斯·克拉克
詹姆斯·怀特
理查德·马斯喀特
杰西卡·玛丽·梅·克诺特
拉米兹·伊克巴尔·纳撒尼
安德鲁·约翰·赫伦
马克·约翰·布鲁斯
拉科马·尼尚萨·贾亚辛格
多梅尼科·卡普罗蒂
戴维·杰克逊·斯托达特
瑞贝卡·维多利亚·鲍恩
克里斯多夫·詹姆斯·莱特
保罗·理查德·穆迪
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Oxford Nanopore Technologies PLC
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Priority to CN202310379929.9A priority Critical patent/CN116334200B/zh
Priority to CN202310379925.0A priority patent/CN116377044B/zh
Publication of CN110168104A publication Critical patent/CN110168104A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores

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  • General Health & Medical Sciences (AREA)
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  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
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  • Genetics & Genomics (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201780083105.XA 2016-12-01 2017-11-29 使用纳米孔表征分析物的方法和系统 Pending CN110168104A (zh)

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Application Number Priority Date Filing Date Title
CN202310379929.9A CN116334200B (zh) 2016-12-01 2017-11-29 使用纳米孔确定多核苷酸特征的方法和用于该方法的复合物
CN202310379925.0A CN116377044B (zh) 2016-12-01 2017-11-29 用于使两个非共价结合的互补核酸链依次易位通过纳米孔的方法和复合物

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GB1620450.5 2016-12-01
GBGB1620450.5A GB201620450D0 (en) 2016-12-01 2016-12-01 Method
US201762471338P 2017-03-14 2017-03-14
US62/471,338 2017-03-14
PCT/GB2017/053603 WO2018100370A1 (en) 2016-12-01 2017-11-29 Methods and systems for characterizing analytes using nanopores

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CN202310379925.0A Division CN116377044B (zh) 2016-12-01 2017-11-29 用于使两个非共价结合的互补核酸链依次易位通过纳米孔的方法和复合物

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CN202310379929.9A Active CN116334200B (zh) 2016-12-01 2017-11-29 使用纳米孔确定多核苷酸特征的方法和用于该方法的复合物

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AU (1) AU2017367238B2 (cg-RX-API-DMAC10.html)
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CN113322180A (zh) * 2021-05-31 2021-08-31 中国科学院物理研究所 基于纳米孔测序的力谱分析方法和分析装置
CN113930406A (zh) * 2021-12-17 2022-01-14 北京齐碳科技有限公司 一种Pif1-like解旋酶及其应用
CN114134142A (zh) * 2021-11-23 2022-03-04 成都齐碳科技有限公司 衔接体、复合物、单链分子、试剂盒、方法和应用
CN114364797A (zh) * 2019-09-18 2022-04-15 株式会社日立高新技术 衔接子分子、该衔接子分子与生物分子结合而成的生物分子-衔接子分子复合体、生物分子分析装置和生物分子分析方法
CN114689672A (zh) * 2021-03-05 2022-07-01 台湾积体电路制造股份有限公司 用于检测生物分子的系统及方法
WO2023125605A1 (zh) * 2021-12-30 2023-07-06 深圳华大生命科学研究院 单分子纳米孔测序方法
CN116478983A (zh) * 2022-11-21 2023-07-25 北京普译生物科技有限公司 一种rna-dna嵌合接头及其应用
CN117587110A (zh) * 2022-08-16 2024-02-23 北京齐碳科技有限公司 富集方法、表征分析物的方法及其装置
WO2025000432A1 (zh) * 2023-06-30 2025-01-02 深圳华大生命科学研究院 利用封闭子进行纳米孔测序的方法

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