CN110167637B - 3-羟基丁酸甘油酯用于偏头痛症状管理 - Google Patents

3-羟基丁酸甘油酯用于偏头痛症状管理 Download PDF

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Publication number
CN110167637B
CN110167637B CN201780078046.7A CN201780078046A CN110167637B CN 110167637 B CN110167637 B CN 110167637B CN 201780078046 A CN201780078046 A CN 201780078046A CN 110167637 B CN110167637 B CN 110167637B
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hydroxybutyrate
glycerol
migraine
mono
fatty acyl
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CN110167637A (zh
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萨米·哈希姆
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Neuroenergy Ventures Inc
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Neuroenergy Ventures Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201780078046.7A 2016-12-23 2017-11-30 3-羟基丁酸甘油酯用于偏头痛症状管理 Active CN110167637B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/389,828 US20180177753A1 (en) 2016-12-23 2016-12-23 Glyceryl 3-hydroxybutyrates for migraine symptom management
US15/389,828 2016-12-23
PCT/US2017/063832 WO2018118369A1 (en) 2016-12-23 2017-11-30 Glyceryl 3-hydroxybutyrates for migraine symptom management

Publications (2)

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CN110167637A CN110167637A (zh) 2019-08-23
CN110167637B true CN110167637B (zh) 2023-03-14

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CN201780078046.7A Active CN110167637B (zh) 2016-12-23 2017-11-30 3-羟基丁酸甘油酯用于偏头痛症状管理

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US (2) US20180177753A1 (https=)
EP (1) EP3558458B1 (https=)
JP (1) JP7108320B2 (https=)
KR (1) KR102390608B1 (https=)
CN (1) CN110167637B (https=)
BR (1) BR112019012431A2 (https=)
CA (1) CA3046350C (https=)
ES (1) ES2962879T3 (https=)
IL (1) IL267540B (https=)
MX (1) MX389468B (https=)
MY (1) MY190308A (https=)
PT (1) PT3558458T (https=)
WO (1) WO2018118369A1 (https=)

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Publication number Publication date
CA3046350A1 (en) 2018-06-28
CA3046350C (en) 2022-08-16
ES2962879T3 (es) 2024-03-21
MY190308A (en) 2022-04-13
KR102390608B1 (ko) 2022-04-25
IL267540B (en) 2022-07-01
EP3558458A4 (en) 2020-08-12
EP3558458B1 (en) 2023-10-18
MX2019006844A (es) 2019-08-16
WO2018118369A1 (en) 2018-06-28
US10792269B2 (en) 2020-10-06
BR112019012431A2 (pt) 2020-04-14
US20190117612A1 (en) 2019-04-25
IL267540A (en) 2019-08-29
PT3558458T (pt) 2023-11-27
KR20190099465A (ko) 2019-08-27
US20180177753A1 (en) 2018-06-28
CN110167637A (zh) 2019-08-23
JP7108320B2 (ja) 2022-07-28
JP2020502250A (ja) 2020-01-23
MX389468B (es) 2025-03-20
EP3558458A1 (en) 2019-10-30

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