JPWO2023004151A5 - - Google Patents
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- Publication number
- JPWO2023004151A5 JPWO2023004151A5 JP2024503840A JP2024503840A JPWO2023004151A5 JP WO2023004151 A5 JPWO2023004151 A5 JP WO2023004151A5 JP 2024503840 A JP2024503840 A JP 2024503840A JP 2024503840 A JP2024503840 A JP 2024503840A JP WO2023004151 A5 JPWO2023004151 A5 JP WO2023004151A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- ester
- progression
- rate
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 17
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical class CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 10
- 150000002148 esters Chemical class 0.000 claims 6
- 210000001525 retina Anatomy 0.000 claims 6
- 208000017442 Retinal disease Diseases 0.000 claims 5
- 230000001590 oxidative effect Effects 0.000 claims 5
- -1 monoglyceride ester Chemical class 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 4
- 206010061818 Disease progression Diseases 0.000 claims 3
- 230000005750 disease progression Effects 0.000 claims 3
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 3
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 3
- 230000000977 initiatory effect Effects 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000000902 placebo Substances 0.000 claims 3
- 229940068196 placebo Drugs 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- 230000037213 diet Effects 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 125000004494 ethyl ester group Chemical group 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163224690P | 2021-07-22 | 2021-07-22 | |
| US202163224679P | 2021-07-22 | 2021-07-22 | |
| US202163224674P | 2021-07-22 | 2021-07-22 | |
| US63/224,679 | 2021-07-22 | ||
| US63/224,690 | 2021-07-22 | ||
| US63/224,674 | 2021-07-22 | ||
| PCT/US2022/038072 WO2023004151A1 (en) | 2021-07-22 | 2022-07-22 | Methods for inhibiting the progression of oxidative retinal diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024526939A JP2024526939A (ja) | 2024-07-19 |
| JPWO2023004151A5 true JPWO2023004151A5 (https=) | 2024-07-29 |
| JP2024526939A5 JP2024526939A5 (https=) | 2024-07-29 |
Family
ID=84979648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024503840A Pending JP2024526939A (ja) | 2021-07-22 | 2022-07-22 | 酸化的網膜疾患の進行を抑制する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250099415A1 (https=) |
| EP (1) | EP4373479A4 (https=) |
| JP (1) | JP2024526939A (https=) |
| KR (1) | KR20240036651A (https=) |
| AU (1) | AU2022313207A1 (https=) |
| CA (1) | CA3227139A1 (https=) |
| IL (1) | IL310210A (https=) |
| WO (1) | WO2023004151A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024049497A1 (en) * | 2022-09-02 | 2024-03-07 | Biojiva Llc | Pharmaceutical compositions of d10-docosahexaenoic acid or esters thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060270739A1 (en) * | 2005-04-28 | 2006-11-30 | Trustees Of Tufts College | Synergistic effects of docosahexaenoic acid (DHA) and carotenoid absorption on macular pigmentation |
| CA2723139A1 (en) * | 2007-07-30 | 2009-02-05 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Dha and pedf, a therapeutic composition for nerve and retinal pigment epithelial cells |
| WO2009058815A2 (en) * | 2007-10-29 | 2009-05-07 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Lipoxin a4 protection for retinal cells |
| EP3689342A1 (en) * | 2011-04-26 | 2020-08-05 | Retrotope, Inc. | Oxidative retinal diseases |
| CA3005983A1 (en) * | 2015-11-23 | 2017-06-01 | Retrotope, Inc. | Site-specific isotopic labeling of 1,4-diene systems |
| CA3117216A1 (en) * | 2018-11-15 | 2020-05-22 | Retrotope, Inc. | Deuterated compounds, compositions, and uses |
-
2022
- 2022-07-22 JP JP2024503840A patent/JP2024526939A/ja active Pending
- 2022-07-22 IL IL310210A patent/IL310210A/en unknown
- 2022-07-22 CA CA3227139A patent/CA3227139A1/en active Pending
- 2022-07-22 US US18/291,016 patent/US20250099415A1/en active Pending
- 2022-07-22 EP EP22846695.9A patent/EP4373479A4/en active Pending
- 2022-07-22 KR KR1020247005941A patent/KR20240036651A/ko active Pending
- 2022-07-22 AU AU2022313207A patent/AU2022313207A1/en active Pending
- 2022-07-22 WO PCT/US2022/038072 patent/WO2023004151A1/en not_active Ceased
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