CN110151932B - Chinese medicinal preparation for treating hypertension, hyperglycemia and hyperlipidemia and preparation method thereof - Google Patents

Abstract

The invention provides a traditional Chinese medicine preparation for treating hypertension, hyperglycemia and hyperlipidemia and a preparation method thereof. The traditional Chinese medicine preparation comprises main medicine powder and auxiliary materials, wherein the main medicine powder comprises selfheal, rhizoma atractylodis, radix scrophulariae, uncaria, houttuynia cordata, radix puerariae, radix stephaniae tetrandrae, rhizoma anemarrhenae, semen raphani, radix rehmanniae preparata, rheum officinale, folium eriobotryae, lumbricus, Chinese yam, radix ophiopogonis, cortex lycii radicis, astragalus mongholicus, hawthorn, polygonum multiflorum, American ginseng, herba epimedii, semen coicis and gardenia, and the auxiliary materials comprise garlic, phaseolus calcaratus and poria cocos. Compared with the related technology, the invention has the effects of directly reaching viscera, relieving thirst, improving sleep, dizziness, headache, fatigue and other symptoms, accelerating the generation of insulin, mainly treating hypertension, hyperglycemia and hyperlipidemia and has unique effect.

Description

Chinese medicinal preparation for treating hypertension, hyperglycemia and hyperlipidemia and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicine health products, in particular to a traditional Chinese medicine preparation for treating hypertension, hyperglycemia and hyperlipidemia and a preparation method thereof.

Background

Hypertension is characterized by the increase of systolic pressure (more than or equal to 140 mm Hg) or diastolic pressure (more than or equal to 90 mm Hg) of human circulatory arterial blood pressure, and patients have dizziness, headache, tight neck plate, fatigue, palpitation and the like. Hyperglycemia is the condition that the glucose content in blood is increased, the abnormal regulation is mainly shown by polydipsia, polyphagia, polyuria, weight loss and the like due to the lack of insulin glucose metabolism, the normal value of fasting blood glucose is below 6.1mmol/L, and the normal value of blood glucose after two hours of meal is below 7.8mmol/L, for example, the range is called hyperglycemia. Hyperlipemia refers to diseases such as coronary heart disease, pancreatitis and atherosclerosis, which are caused by high blood lipid level and seriously harm human health, and hyperlipemia is divided into primary and secondary diseases, wherein the primary disease is caused by environmental factors, and the secondary disease is mostly caused by metabolic disorders or is related to age factors.

At present, various products or health care products for treating hypertension, hyperglycemia and hyperlipidemia exist in the market, but medicines for taking the medicines are different, and the treatment time and the treatment effect are not ideal.

Disclosure of Invention

In order to solve the defects of the existing similar products, the invention provides a traditional Chinese medicine powder preparation suitable for treating hypertension, hyperglycemia and hyperlipidemia and a preparation method thereof.

The invention aims to provide a traditional Chinese medicine preparation for treating hypertension, hyperglycemia and hyperlipidemia, which comprises main medicine powder and auxiliary materials, wherein the main medicine powder comprises 5-10 parts of selfheal, 1-1.5 parts of rhizoma atractylodis, 0.5-1.5 parts of radix scrophulariae, 1-1.5 parts of uncaria, 3-5 parts of houttuynia cordata, 3-4.5 parts of radix puerariae, 1.5-3 parts of radix stephaniae tetrandrae, 1-2.5 parts of rhizoma anemarrhenae, 1-1.5 parts of semen raphani, 2-4 parts of radix rehmanniae preparata, 1-2.5 parts of rheum officinale, 1-1.5 parts of folium eriobotryae, 3-4.5 parts of earthworm, 1.5-2.5 parts of Chinese yam, 0.5-1 part of radix ophiopogonis, 0.5-1 part of cortex lycii, 3-4.5 parts of radix astragali, 1.5-2 parts of hawthorn, 1-1.5 parts of polygonum multiflorum, 5-8 parts of herba epimedii, 0.5-1.5 parts of semen coicis, 0.5-1.5 parts, 0.5-1 part of gardenia; the auxiliary materials comprise 5-8 parts of garlic, 1-1.5 parts of red bean and 1-2.5 parts of tuckahoe.

Preferably, the proportion of the main drug powder is 710-950 parts.

The invention also provides a preparation method of the traditional Chinese medicine preparation for treating hypertension, hyperglycemia and hyperlipidemia, which comprises the following steps:

(1) preparing main drug powder: weighing the traditional Chinese medicines according to the percentage, and grinding the traditional Chinese medicines into fine powder;

(2) grinding the auxiliary materials of 5-8 parts of garlic, 1-2.5 parts of tuckahoe and 1-1.5 parts of red bean into fine powder;

(3) uniformly mixing 710 and 950 parts of the main drug fine powder obtained in the step (1) with 65% of the total weight of the auxiliary material components, and standing for 8-12 hours to obtain mixed medicinal powder;

(4) adding 35% of the total weight of the auxiliary materials into the mixed medicinal powder in the step (3), uniformly mixing, and standing for 8-12 hours;

(5) and standing for 24-48 hours, and then packaging.

Preferably, the traditional Chinese medicines of the components are dried for 8 hours before being ground into fine powder in the step (1).

Pharmacological analysis:

figwort root: has effects in clearing away heat, cooling blood, purging pathogenic fire, removing toxic substances, and nourishing yin; the main treatment is as follows: pathogenic heat entering nutrient system, invasion of pericardium, toxic heat and macula, impairment of yin by fever, crimson tongue with polydipsia, constipation due to body fluid consumption, bone-steaming, overstrain cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, superficial infection and sore.

Radish seed: has effects in promoting digestion, relieving flatulence, lowering qi, and eliminating phlegm; it can be used for treating food stagnation, abdominal distention and pain, constipation, stagnation, dysentery, phlegm stagnation, asthma, and cough.

Selfheal: has effects of clearing pathogenic fire, improving eyesight, resolving hard mass, and relieving swelling; mainly treats conjunctival congestion, swelling and pain, eyeball nyctalgia, headache, dizziness, scrofula, goiter and mammary abscess, swelling and pain; goiter, tuberculous lymphadenitis, hyperplasia of mammary glands, and hypertension.

Rhizoma atractylodis: has effects of eliminating dampness, invigorating spleen, dispelling pathogenic wind, dispelling cold, and improving eyesight; mainly treats abdominal distension, diarrhea, edema, beriberi flaccidity 36484m, rheumatism, cold and night blindness.

Cortex lycii radicis: has effects of cooling blood, removing heat, clearing lung-heat, and lowering fire; can be used for treating hectic fever due to yin deficiency, hectic fever, night sweat, cough due to lung heat, hemoptysis, epistaxis, internal heat, and diabetes.

Earthworm: has effects of clearing heat, arresting convulsion, dredging collaterals, relieving asthma, and promoting urination; can be used for treating hyperpyrexia, unconsciousness, epilepsy, convulsion, arthralgia, numbness of limbs, hemiplegia, cough and asthma due to lung heat, oliguria, edema, and hypertension.

Rhubarb: has effects in purging heat, promoting intestinal function, cooling blood, removing toxic materials, dispelling blood stasis, and dredging channels; can be used for treating excessive heat constipation, abdominal pain due to stagnation, dysentery, jaundice due to damp-heat pathogen, hematemesis, epistaxis, conjunctival congestion, pharyngeal swelling, acute appendicitis, abdominal pain, carbuncle, furuncle, amenorrhea due to blood stasis, and traumatic injury, and can be used for treating scald due to water and fire; upper gastrointestinal hemorrhage.

Stephania tetrandra: has effects in inducing diuresis to alleviate edema, dispelling pathogenic wind and relieving pain; mainly treats edema beriberi, dysuresia, eczema, sore and toxin and rheumatism pain; hypertension is caused.

Uncaria: has effects of clearing heat, calming liver, calming endogenous wind and arresting convulsion; can be used for treating headache, vertigo, common cold, convulsion, convulsive epilepsy, and eclampsia during pregnancy; hypertension is caused.

Kudzu root: has effects in expelling pathogenic factors from muscles, relieving fever, promoting salivation, promoting eruption, invigorating yang, and relieving diarrhea; can be used for treating fever, headache, stiffness and pain of neck and back, thirst, diabetes, measles without adequate eruption, dysentery, and diarrhea; hypertension neck and neck pain.

Astragalus root: has effects of invigorating qi, consolidating superficial resistance, promoting urination, expelling pus, healing sore, and promoting granulation; mainly treats qi deficiency and hypodynamia, anorexia and loose stool, collapse of middle-jiao energy, chronic diarrhea and rectocele, hematochezia and metrorrhagia, exterior deficiency and spontaneous perspiration, qi deficiency and edema, carbuncle, cellulitis and ulceration difficulty, chronic ulceration and no astringency, blood deficiency and yellow atrophy, internal heat and thirst quenching; proteinuria due to chronic nephritis and diabetes.

Loquat leaf: has effects in clearing lung-heat, relieving cough, lowering adverse qi, and relieving vomit; can be used for treating cough due to lung heat, asthma, vomiting due to stomach heat, dysphoria with smothery sensation, and thirst.

Houttuynia cordata: has effects in clearing away heat and toxic materials, eliminating carbuncle, expelling pus, promoting urination, and treating stranguria; it can be used for treating lung abscess, emesis, phlegm heat, cough, dysentery, pyretic stranguria, carbuncle, swelling, and skin ulcer.

Rhizoma anemarrhenae: has effects of clearing heat, purging pathogenic fire, promoting fluid production, and moistening dryness; can be used for treating common cold, fever, polydipsia, lung heat, cough, hectic fever, internal heat, diabetes, and constipation.

Gardenia: has the following fruit: purging pathogenic fire, relieving restlessness, clearing away heat, promoting urination, cooling blood, and removing toxic substance; can be used for treating vexation due to fever, jaundice, dark urine, stranguria with blood, hematemesis, epistaxis, conjunctival congestion, swelling and pain, and pyocutaneous disease due to pathogenic fire; it can be used for treating sprain, contusion and pain.

Herba epimedii: has effects in invigorating kidney yang, strengthening muscle and bone, and dispelling pathogenic wind and dampness; can be used for treating sexual impotence, spermatorrhea, tendons and bones flaccidity, rheumatalgia, numbness and contracture; climacteric hypertension.

American ginseng: has effects in invigorating qi, nourishing yin, clearing away heat, and promoting salivation; can be used for treating deficiency of qi and yin, internal heat, cough, asthma, phlegm, asthenia, vexation, fatigue, diabetes, xerostomia, and dry throat.

Prepared rhizome of rehmannia: has effects in replenishing blood, moistening, replenishing vital essence, and replenishing marrow; can be used for treating sallow complexion, vertigo, palpitation, menoxenia, metrorrhagia, yin deficiency of liver and kidney, hectic fever, night sweat, spermatorrhea, sexual impotence, infertility, soreness of waist and knees, tinnitus, deafness, blurred vision, premature gray hair, diabetes, constipation, renal deficiency, and dyspnea.

Fleece-flower root: has effects of removing toxic substance, resolving carbuncle, loosening bowel and relieving constipation; mainly treats scrofula, sores and carbuncles, rubella, pruritus, intestinal dryness and constipation; hyperlipidemia.

Tuckahoe, poria cocos: has effects of promoting diuresis, eliminating dampness, invigorating spleen, and calming heart. It can be used for treating edema, oliguria, palpitation due to phlegm and fluid retention, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.

Radix ophiopogonis: has effects in nourishing yin, promoting salivation, moistening lung, and clearing away heart-fire; it is mainly used for treating dry cough due to lung dryness. Cough due to consumptive disease, thirst due to body fluid consumption, vexation, insomnia, internal heat, diabetes, constipation due to intestinal dryness; and (4) pharyngeal diphtheria.

Chinese yam: has effects in invigorating spleen, nourishing stomach, promoting salivation, tonifying lung, and tonifying kidney; it can be used for treating spleen deficiency, anorexia, chronic diarrhea, cough and asthma due to lung deficiency, spermatorrhea due to kidney deficiency, leukorrhagia, frequent micturition, and diabetes due to deficiency heat.

Hawthorn fruit: has effects in promoting digestion, invigorating stomach, promoting qi circulation, and dispelling blood stasis; can be used for treating dyspepsia, abdominal distention, dysentery, abdominal pain, amenorrhea due to blood stasis, puerperal blood stasis, stabbing pain of heart and abdomen, and hernia pain; hyperlipidemia.

Small red beans: has effects in inducing diuresis to alleviate edema, removing toxic substance and expelling pus; it can be used for treating edema, tinea pedis, edema of limbs, jaundice, dark urine, rheumatism, pyretic arthralgia, carbuncle, suppurative sore, intestinal carbuncle, and abdominal pain.

Garlic: has effects in invigorating spleen, killing parasite, and removing toxic materials; it can be used for treating carbuncle, jaundice, malignant sore, and bacillary dysentery and preventing common cold.

Coix seed: has effects in invigorating spleen, eliminating dampness, relieving arthralgia, relieving diarrhea, clearing away heat, and expelling pathogenic accumulation; mainly treats edema, beriberi, dysuresia, damp arthralgia, contracture, spleen deficiency, diarrhea, pulmonary abscess and intestinal abscess; flat warts.

Compared with the related technology, the invention has the beneficial effects that:

the Chinese medicinal composition has the effects of directly reaching viscera, relieving thirst, improving sleep, dizziness, headache, fatigue and other symptoms, accelerating the generation of insulin, mainly treating hypertension, hyperglycemia and hyperlipidemia and has unique effect;

the traditional Chinese medicine powder preparation disclosed by the invention is small in dosage, convenient to use and carry, can reach viscera directly, relieve thirst, improve sleep, dizziness, headache, fatigue and other symptoms, has the effect of accelerating insulin production, is quick to absorb, has an obvious curative effect, does not have side effects or drug resistance, and is beneficial to timely alleviating symptoms of patients.

Detailed Description

The technical solution of the present invention is further described in detail with reference to the following specific examples, which should not be construed as limiting the present invention.

A Chinese medicinal powder preparation for treating hypertension, hyperglycemia and hyperlipemia and its preparation method are provided. The method comprises the following steps:

(1) weighing the following raw materials in parts by weight:

5-10 parts of selfheal, 1-1.5 parts of rhizoma atractylodis, 0.5-1.5 parts of radix scrophulariae, 1-1.5 parts of uncaria, 3-5 parts of houttuynia cordata, 3-4.5 parts of radix puerariae, 1.5-3 parts of radix stephaniae tetrandrae, 1-2.5 parts of rhizoma anemarrhenae, 1-1.5 parts of semen raphani, 2-4 parts of radix rehmanniae preparata, 1-2.5 parts of rheum officinale, 1-1.5 parts of loquat leaves, 3-4.5 parts of lumbricus, 1.5-2.5 parts of Chinese yam, 0.5-1 part of radix ophiopogonis, 0.5-1 part of cortex lycii, 3-4.5 parts of astragalus membranaceus, 1.5-2 parts of hawthorn, 1-1.5 parts of fleece-flower root, 5-8 parts of American ginseng, 0.5-1.5 parts of herba epimedii, 0.5-1 part of semen coicis and 0.5.

(2) Drying the 23 raw materials in the sun for 8 hours, and grinding into fine powder.

(3) The auxiliary materials of 5 to 8 parts of garlic, 1 to 2.5 parts of tuckahoe and 1 to 1.5 parts of red bean are ground into fine powder for later use.

(4) Uniformly mixing 710 and 950 parts of the main drug fine powder obtained in the step (1) with 65% of the total weight of the auxiliary material components, standing for 8-12 hours to obtain mixed medicinal powder, and standing.

(5) And (3) adding 35% of the total weight of the auxiliary materials into the mixed medicinal powder in the step (3), uniformly mixing, and standing and drying for 8-12 hours.

(6) And standing for 24-48 hours, and then packaging.

Method of treatment

The invention relates to a Chinese medicinal powder preparation for treating hypertension, hyperglycemia and hyperlipidemia. The medicine is taken after being boiled with 15 g of medicine powder for about 10 minutes, the drinking time interval is 3-4 hours every time, three times every day, hypertension, hyperglycemia and hyperlipidemia begin to decline after five to six days, and after being taken for one month, the symptoms of hypertension, hyperglycemia and hyperlipidemia are all normally cured.

Therapeutic results

Clinical experiment one

Guangdong luodin City Luo town, 55 years old, hypertension were treated everywhere for many years, with the annual contraction pressure at about 170 mm tribute column, the diastolic pressure at about 115 mm tribute column, dizziness, headache, neck tightness, fatigue, palpitation, etc. The Chinese medicinal powder preparation for treating hypertension introduced by friends in 2010 is taken by being boiled with 15 g of Chinese medicinal powder and 100 ℃ boiled water for 10 minutes. Three times a day (three and four hours apart for each administration), the experimental results show that the systolic pressure is reduced to 145 mmHg and the diastolic pressure is reduced to 100 mmHg for six consecutive days, and that the systolic pressure is reduced to about 120 mmHg and the diastolic pressure is reduced to about 80 mmHg after fifteen consecutive days of administration. If the patient is unstable, the patient can drink the tea for one month, the symptoms of the patient can recover to the stable systolic pressure of 110 mmHg and the stable diastolic pressure of 80 mmHg, and the patient can recover to normal.

Clinical experiment 2

The Guangdong Luoding city with town is 50 years old, hyperglycemic, perennial fasting blood sugar is about 13mmol/L, two hours after meal is about 19mmol/L, dizziness, headache, fatigue and the like, and the doctor seeking is fruitless in four places for many years. The Chinese medicinal powder preparation for treating hyperglycemia is introduced by friends in 2009, 15 g of the Chinese medicinal powder is taken after being washed away at 100 ℃ for 10 minutes, three times a day (three and four hours are taken every time), and the experimental result shows that after 7 continuous days, the fasting blood glucose is reduced to 8mmol/L and the postprandial two hours are reduced to 10 mmol/L. After drinking for fifteen days continuously, the fasting blood sugar is reduced to 5.5mmol/L, and the two hours after meal is reduced to 7 mmol/L. If the food is unstable, the symptoms are stable at 4.1-5.2mmol/L in fasting state and at 6-7mmol/L after meal for twenty-five days after drinking, so far, the food is normal.

Claims (3)

1. A Chinese medicinal preparation for treating hypertension and hyperglycemia comprises main medicinal powder and adjuvants, the Chinese medicinal powder is characterized by comprising 5-10 parts of selfheal, 1-1.5 parts of rhizoma atractylodis, 0.5-1.5 parts of radix scrophulariae, 1-1.5 parts of uncaria, 3-5 parts of houttuynia cordata, 3-4.5 parts of radix puerariae, 1.5-3 parts of radix stephaniae tetrandrae, 1-2.5 parts of rhizoma anemarrhenae, 1-1.5 parts of semen raphani, 2-4 parts of radix rehmanniae preparata, 1-2.5 parts of rheum officinale, 1-1.5 parts of folium eriobotryae, 3-4.5 parts of lumbricus, 1.5-2.5 parts of Chinese yam, 0.5-1 part of radix ophiopogonis, 0.5-1 part of cortex lycii, 3-4.5 parts of radix astragali, 1.5-2 parts of hawthorn, 1-1.5 parts of polygonum multiflorum, 5-8 parts of American ginseng, 0.5-1.5 parts of herba epimedii, 0.5-1 part of semen coicis and 0.5-1; the auxiliary materials comprise garlic, red bean and tuckahoe; the main drug powder is mixed with garlic, tuckahoe and phaseolus calcaratus in the following proportion: 710-950 parts of main drug powder, 5-8 parts of garlic, 1-2.5 parts of poria cocos and 1-1.5 parts of phaseolus calcaratus.

2. A method for preparing the Chinese medicinal preparation for treating hypertension and hyperglycemia of claim 1, which comprises the following steps:

(1) preparing main drug powder: weighing the traditional Chinese medicines according to the proportion, and grinding into fine powder;

(2) grinding the auxiliary materials of 5-8 parts of garlic, 1-2.5 parts of tuckahoe and 1-1.5 parts of red bean into fine powder;

(3) uniformly mixing 710 and 950 parts of the main drug powder in the step (1) with 65% of the total weight of the auxiliary material components, and standing for 8-12 hours to obtain mixed powder;

(4) adding 35% of the total weight of the auxiliary materials into the mixed medicinal powder in the step (3), uniformly mixing, and standing for 8-12 hours;

(5) and standing for 24-48 hours, and then packaging.

3. The preparation method of claim 2, wherein the traditional Chinese medicines in the step (1) are dried for 8 hours before being ground into fine powder.