CN110151683A - A kind of moistening lung to arrest cough autumn pear grease and preparation method thereof - Google Patents
A kind of moistening lung to arrest cough autumn pear grease and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/75—Rutaceae (Rue family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A61P11/00—Drugs for disorders of the respiratory system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/14—Antitussive agents
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The embodiment of the invention discloses a kind of moistening lung to arrest cough autumn pear grease and preparation method thereof, the moistening lung to arrest cough autumn pear grease is by including that following raw material is made: 4500-5500 parts of autumn pear, 4500-5500 parts of pear, 200-300 parts of ginger, 1200-1800 parts of lotus root, 300-400 parts of tendril-leaved fritillary bulb powder, 400-600 parts of Exocarpium Citri Grandis, 250-350 parts of Poria cocos, 800-1200 parts of jujube, 1200-1800 parts of loquat, 250-350 parts of loguat leaf, Radix Ophiopogonis 400-600 part, 250-350 parts of campanulaceae, 300-400 parts of Radix Glycyrrhizae, 300-400 parts of Radix Astragali and 1800-2200 parts of honey;The autumn pear grease that the present invention is prepared has moistening lung to arrest cough, clearing heat and eliminating phlegm, heart clearing, lung moistening, promotion appetite and other effects, and has cure rate height, curative effect fast and significant effect cough.
Description
Technical field
The present embodiments relate to technical field of traditional Chinese medicines, and in particular to a kind of moistening lung to arrest cough autumn pear grease and preparation method thereof.
Background technique
Autumn pear grease is also snow pear paste, is one of traditional herbal cuisine, starts from the Tang Dynasty according to legend.With selected autumn pear (or pear, snow
Flower pears) it is primary raw material, it is equipped with other cough-relievings, eliminating the phlegm, promotes the production of body fluid, moistening lung medicine, such as Radix Rehmanniae, pueraria lobata, radish, Radix Ophiopogonis, rhizoma nelumbinis, ginger
Herbal cuisine drink made of the raw material of the integration of drinking and medicinal herbs such as juice, fritillaria, honey boil meticulously is clinically usually used in treatment because of the dry wound of heat
Lung heat polydipsia caused by saliva just dries the respiratory passage diseases such as bored, internal lesion caused by overexertion lung yin, cough uttering phlegm, chronic cough hemoptysis.
Existing autumn pear grease is mostly pear juice extract, and a certain amount of auxiliary material, such as additive and plastic agent etc., function is added
It imitates weaker and relatively simple;Some traditional Chinese medicine ingredients are added in still other autumn pear grease, preferably to improve the function of autumn pear grease
Effect leads to that effect is poor, Time of Administration is long since the compatibility of the traditional Chinese medicinal components of addition is bad, is easy to recur.
Summary of the invention
For this purpose, first aspect of the embodiment of the present invention provides a kind of moistening lung to arrest cough autumn pear grease, with solve in the prior art due to
The traditional Chinese medicinal components compatibility bad the effect of causing added in autumn pear grease is weaker, the longer problem of Time of Administration.
Second aspect of the embodiment of the present invention provides a kind of autumn pear grease and preparation method thereof, which can sufficiently extract
Effective component in each raw material, and the impurity in honey can be removed and kill microorganism, and crush ferment, it can preferably mention
The drug effect of height preparation autumn pear grease.
To achieve the goals above, the embodiment of the present invention provides the following technical solutions:
A kind of autumn pear grease is provided according to a first aspect of the embodiments of the present invention, and the autumn pear grease is by including that following parts by weight are former
Material is made:
4500-5500 parts of autumn pear, 4500-5500 parts of pear, 200-300 parts of ginger, 1200-1800 parts of lotus root, tendril-leaved fritillary bulb powder
300-400 parts, 400-600 parts of Exocarpium Citri Grandis, 250-350 parts of Poria cocos, 800-1200 parts of jujube, 1200-1800 parts of loquat, loguat leaf
250-350 parts, Radix Ophiopogonis 400-600 part, 250-350 parts of campanulaceae, 300-400 parts of Radix Glycyrrhizae, 300-400 parts of Radix Astragali and honey 1800-
2200 parts.
The present invention passes through the specific selection of above-mentioned raw materials, and according to theory of traditional Chinese medical science, according to the preparation of specified weight part proportion
It, can be under each raw material synergistic effect, so that the autumn pear grease being prepared has moistening lung to arrest cough, clearing heat and eliminating phlegm, clear at autumn pear grease
Heart moistening lung promotes appetite, antitussive and expectorant, antitoxic heart-soothing and sedative, sharp intestine and small intestine, clear larynx fall fire, relieving restlessness quench one's thirst, moisturize the wind that disappears, solution of sobering up
The effect of poison, clearing lung-heat moistening lung, nourishing the stomach stomach function regulating, has cure rate height, curative effect fast and significant effect cough.
Each raw material that the present invention uses is as follows:
Autumn pear: the sweet of low station acid of its property has reducing fever and causing diuresis, throat soothing decompression, heart clearing, lung moistening, work antibechic timid phlegm, slaked thirst and help produce saliva
With cyesedema and the hypertension of pregnancy can be treated;It also has tranquilizing and allaying excitement, nourishing heart liver protection, anti-inflammatory analgesic and other effects, there is prevention and treatment
The effect of pulmonary infection and hepatitis;The pears stewed well often are eaten, body fluid in mouth is can increase, prevents dry mouth and lips, can not only protect throat,
It is also the dietotherapy product of pneumonia, bronchitis and hepatitis;Autumn pear and other compatibility of drugs with body-fluid-generating heat-clearing cough-relieving, moistening lung, are used
To treat because of the scorching all diseases hurt caused by saliva;Autumn pear has the function of to promote the production of body fluid, fall fire, yin-nourishing, moistening lung, cough-relieving blood etc.;Autumn pear has
It treats because of the dry lung heat polydipsia hurt caused by saliva of heat, just dry the respiratory passage diseases such as bored, internal lesion caused by overexertion lung yin, cough uttering phlegm, chronic cough hemoptysis;
Adjustable blood pressure, promotes appetite, moistening lung to arrest cough, clearing heat and eliminating phlegm, antitoxic heart-soothing and sedative;Except the stomach cold of insufficiency type and tripe patient is let out, women and children the old and the weak is all
It is drinkable.
Pear: Compendium of Material Medica is doomed the function of pear are as follows: " heat of the clear six internal organs of survivor, ripe person grow the yin of the five internal organs ";According to
China's pharmacopeia " new compilation of materia medica " is recorded, pears, and the sweet of low station sour knife of property has heart clearing, lung moistening, sharp intestine and small intestine, antitussive and expectorant, clear larynx drop
Fire, relieving restlessness are quenched one's thirst, and the wind that disappears is moisturized, removing toxic substances and other effects of sobering up;According to modern medical research has found that, pears to pulmonary tuberculosis, tracheitis and on
The diseases such as the throat that the patient of respiratory tract infection occurs is done, itches, and pain, hoarse voice, phlegm is thick, constipation, urine are red are all effective in cure.Pears also have
Reduce blood pressure, nourishing yin and clearing heat the effect of, suffer from hypertension, heart disease, hepatitis, cirrhosis patient, often eat a little pears and be very beneficial,
And appetite can be promoted, it helps digest.
Poria cocos: nature and flavor are sweet, light, mild-natured;Return heart, lung, spleen, kidney channel;Poria cocos has inducing diuresis for removing edema, excreting dampness, invigorating the spleen, calming heart
The effect of;Cure mainly oedema, phlegm retention, splenasthenic diarrhea, palpitaition, insomnia, function inducing diuresis for removing edema, excreting dampness, invigorating the spleen, calming heart;This product is sweet in flavor
And it is light, it is sweet, can mend, it is light, can seep, medicinal peace, not only can eliminating evil, but also can righting, Li Shui is without hurting healthy tendency, actually inducing diuresis for removing edema
Key medicine;Phlegm retention, this product is kind to seep and sluices wet, makes wet without gathering, phlegm is had no way of life;Splenasthenic diarrhea, this product energy invigorating the spleen excreting dampness and antidiarrheal,
Especially it is suitable for insufficiency of the spleen with overabundance of dampness diarrhea;Palpitaition, insomnia, this product heart-spleen boosting and antitoxic heart-soothing and sedative.
Ginger: smell is pungent, and tepor is nontoxic;Ginger has diverging, preventing or arresting vomiting, cough-relieving and other effects;It cures mainly long term usage and removes foul smell, lead to
Gods return the five internal organs, exorcising fever and chills, and cold headache is had a stuffy nose, and cough with dyspnea, anti-nausea removes gas under phlegm, go aqueous vapor full, under the main heart
Shoot.
Lotus root: meridian distribution of property and flavor: it is sweet in flavor, it is cold in nature;Return heart, liver, spleen, stomach meridian lotus root, lotus root, also known as lotus rhizome belong to Nelumbonaceae plant roots and stems, can
Canteen is also pharmaceutically acceptable;Powder is made with lotus root, can help digestion antidiarrheal, and heat-clearing of whetting the appetite, nourishing is nourished one's nature, and prevent internal haemorrhage, be women and children child old woman, body
The first-class supping of weak more patients and the good treasure of nourishing, lotus root have beneficial to heart, have and boost metabolism, prevent pachylosis
Effect;The attending effectiveness of lotus root: clearing heat and cooling blood: lotus rhizome is raw with cold in nature, has clearing heat and cooling blood effect, can be used to treat hot illness;Lotus
Lotus root more liquid sweet in flavor, bleeding from five sense organs or subcutaneous tissue thirsty to pyreticosis, hemoptysis, lower blood person are especially useful;Defaecation antidiarrheal, spleen benefiting and stimulating the appetite: containing glutinous in lotus rhizome
Liquid eggs is white and dietary fiber, can combine with cholate in human body, cholesterol and triglycerides in food, arrange it from excrement
Out, to reduce the absorption of lipid;Lotus rhizome gives out a kind of unique faint scent, also contains tannin, has certain invigorating the spleen to arrest diarrhea to act on, energy
It improves a poor appetite, promotes digestion, appetizing is beneficial to anorexia, loss of appetite person gets well in being good for;Beneficial blood myogenic: the battalion of lotus root
Feeding value is very high, and rich in microelements such as iron, calcium, phytoprotein, vitamin and content of starch are also very abundant, has apparent
Tonifying Qi and blood enhances human immunity effect;Therefore Chinese medicine claims it: " main bowl spares is reposed, benefiting energy ";Hemostasis stasis: lotus root contains greatly
The tannic acid of amount has vasoconstriction effect, can be used to stop blooding;Lotus root can also cool blood, dissipate blood, Chinese medicine think its hemostasis without staying the stasis of blood,
It is the diet good food of pyreticosis mass formed by blood stasis;Defaecation hemostasis spleen benefiting and stimulating the appetite: it will be smelt when eating lotus root, a kind of uniqueness can be given out in lotus root
Faint scent, also contain tannin, have the function of certain invigorating the spleen to arrest diarrhea, the appetite of people can also be promoted by eating lotus root, promote digestion, be reduced
The case where indigestion, the patient of loss of appetite are very suitable to often eat of lotus root;It is also fine containing mucus albumen and diet in lotus root
Dimension can be such that it is discharged from excrement, reduce the absorption of lipid in conjunction with the cholesterol in cholate in human body, food.
Bulbus fritillariae cirrhosae: bulbus fritillariae cirrhosae bitter, sweet, cold nature;Return lung, the heart channel of Hang-Shaoyin;With clearing heat and eliminating phlegm, moistening lung to arrest cough, mass dissipating and swelling eliminating
The effect of;Cure mainly cough due to consumptive disease, lung-heat type cough, scrofula, acute mastitis, pulmonary abscess, matter profit let out it is scattered, drop and microlitre.
Jujube: sweet in flavor, warm-natured, returns spleen, stomach meridian;Jujube rich in protein, fat, carbohydrate, carrotene, B family vitamin,
The nutritional ingredients such as vitamin C, citrin and calcium, phosphorus, iron and cyclic adenosine monophosphate.Wherein ascorbic content name in fruit
Column first has the laudatory title of vitamin king, has the effect of blood-enriching face-nourishing treatment insomnia;Although jujube nutritive value is high, tooth
Tooth is bad to be eaten less, soaked can drink, can also endure brown sugar jujube medlar soup, nutritive value is also good, and Anti-dental injury
Tooth;Cyclic adenosine monophosphate contained by jujube is the essential component of human body cell energetic supersession, can enhance muscular strength, eliminate fatigue,
Blood vessel is expanded, increases myocardial contractive power, improve myocardial nutrition, has good effect to prevention and treatment disease of cardiovascular system.
Campanulaceae: it is mild-natured, it is bitter, pungent;It is distributed in lung channel;With clearing lung and eliminating the phlegm, relieving sore throat and evacuating pus and other effects;Main treatment coughing with a lot of sputum,
Chest and diaphragm expire vexed, pharyngalgia hoarse voice, lung subcutaneous ulcer pyemesis;Gavage the thick saponin(e of campanulaceae with anti-inflammatory, calm, analgesia, antipyretic, relaxing smooth muscle,
Prevent and treat digestive tract ulcer effect.
Loquat: smell is sweet, sour, puts down, nontoxic;Have effects that have moistening lung to arrest cough, quench the thirst, stomach function regulating;Be usually used in dry throat polydipsia,
The diseases such as cough haematemesis, hiccup;Not only pulp can be used as medicine loquat, core, expelling phlegm and arresting coughing, harmonizing stomach and lowering adverse Qi;For treating lung heat and cough
It coughs, illnesss, leaf, the root such as chronic cough is not cured, dry throat and mouth and stomach Qi deficiency also have medical value;Fresh loquat is cleaned, and eats it raw, energy
Treat the discomforts such as dry polydipsia.
Loguat leaf: bitter in taste, micro-pungent, cold nature;It attaches to the lung and stomach meridians, micro-perfume drops clearly;Lung heat clearing away, sputum eliminating;This product bitter cold, can clearing lung-heat
Heat drops lung qi with cough-relieving, is usually used in treating cough with lung heat, abundant expectoration color Huang;Harmonizing stomach and lowering adverse Qi, can drop stomach Qi and preventing or arresting vomiting is inverse, be used for stomach
Thermally-induced vomitting is inverse;Quench the thirst: this product can treat dry and quench one's thirst, lung wind face sore, acne;Loguat leaf has clearing lung and relieving cough, stomach function regulating benefit
Urine, the effect of quenching the thirst;There are treatment lung feverish cough, hemoptysis, bleeding from five sense organs or subcutaneous tissue, stomach hot vomiting effect.
Radix Ophiopogonis: sweet in flavor, slight bitter, cold nature return stomach, lung, the heart channel of Hang-Shaoyin, with Yin nourishing and lung moistening, reinforcing stomach reg fluid, relieving restlessness and restlessness function
Effect, for diseases such as dryness of the lung dry cough, cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, injury thirst, Heat Diabetes, vexed insomnia, dry constipation of intestines;" this
Careless lease making " Radix Ophiopogonis is classified as to the top grade of Yin nourishing and lung moistening, say its " long term usage is made light of one's life by commiting suicide, not old not hungry ";Radix Ophiopogonis has moistening lung and clearing away the heart-fire, purges heat
It promotes the production of body fluid, resolving sputum preventing or arresting vomiting, controls row water of coughing, stomach can be entered with nourishing the stomach liquid, stimulating appetite can more enter spleen to help spleen to dissipate and be skillful in lung, and Dingchuan is peaceful
It coughs." Radix Ophiopogonis have the function of it is antifatigue, remove free radical, improve cellular immune function and hypoglycemic;In addition, there is town in Radix Ophiopogonis
Quiet, hypnosis, resist myocardial ischemia, anti-arrhythmia, it is antitumor the effects of, especially there is many-sided function to promoting senior health and fitness
Effect;In addition, Radix Ophiopogonis is in sugared friendly prescription there are also the effect for promoting islet cell function to restore, increasing hepatic glycogen, reducing blood glucose
Regular supplies;Radix Ophiopogonis can take appropriate Radix Ophiopogonis on behalf of the tea, and boiled water impregnates, and several times, the symptom of thirsty can be effectively relieved in more clothes daily,
Part of diabetes mellitus patient's deficiency of both qi and yin, therefore when drinking Radix Ophiopogonis water, it can allow some Radix Codonopsis, can more play the role of tonifying Qi.
Radix Glycyrrhizae: it is mild-natured, it is sweet in flavor;Thoughts of returning home warp, stomach meridian, the spleen channel, lung channel;With invigorate the spleen and benefit qi, cough-relieving apophlegmatic, emergency analgesic therapy,
Mediation property of medicine and other effects;For poisoning salvage guide, treatment is weakness of the spleen and the stomach, contraction is anxious in the deficiency of qi in middle-jiao, cough and asthma, skin sore, abdomen
Have a pain, mitigate drug it is strong, solution poisoning of drug;Use is preferably processed in heat-clearing Ying Shengyong, bowl spares.
Radix Astragali: meridian distribution of property and flavor: nature and flavor: sweet, tepor;Channel tropism: return lung, spleen, liver and kidney channel.Radix Astragali is that the common people often eat
Pure natural product, folklore the jingle of " often drinking astragali seu Hedysari Decoction, disease-prevention health health ", mean through common Radix Astragali decoction or bubble
Water on behalf of the tea, has good disease-prevention health effect.Radix Astragali and ginseng belong to tonifying Qi good medicine, and ginseng, which biases toward, to reinforce vital energy, and return
Sun rescue it is inverse, be usually used in collapse, shock etc. acute diseases, effect it is preferable;And Radix Astragali is then based on qi-restoratives, be usually used in body decline with the passing of time, speech
Low, thin and weak pulse person.Some people one meet Changes in weather and are easy for catching a cold, and Chinese medicine is known as " table is not solid ", can consolidate table with Radix Astragali,
Informal dress Radix Astragali can be to avoid regular flu;Radix Astragali have enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress,
Decompression and wide antibacterial action;Experimental nephritis proteinuria can be eliminated, myocardial contractive power is enhanced, adjusts blood-sugar content.It is yellow
Stilbene can not only coronary artery dilator, improve myocardial blood supply, improve immune function, and be capable of the process of delaying cell aging.
Further, the raw material further includes 800-1200 parts of rock sugar.
Further, the autumn pear grease is by including that following raw material is made:
5000 parts of autumn pear, 5000 parts of pear, 250 parts of ginger, 1500 parts of lotus root, 350 parts of tendril-leaved fritillary bulb powder, 500 parts of Exocarpium Citri Grandis, Poria cocos
300 parts, 1000 parts of jujube, 1500 parts of loquat, 300 parts of loguat leaf, 500 parts of Radix Ophiopogonis, 300 parts of campanulaceae, 350 parts of Radix Glycyrrhizae, Radix Astragali 350
Part and 2000 parts of honey.
Further, the Exocarpium Citri Grandis is prepared via a method which to obtain:
The immature Exocarpium Citri Grandis fruit of golden texturing Exocarpium Citri Rubrum is won, is placed in earth kiln and with bamboo, mulberry, reed, ash and willow
Carpentery workshop is that fuel carries out low temperature drying to get the Exocarpium Citri Grandis;Preferably, the low temperature drying temperature is 50-60 DEG C;Time is
6-8 days;It is stored 3 years or more it is highly preferred that Exocarpium Citri Grandis is placed at shady and cool ventilation;It can be slow, scattered in heating by the above method
The hot moisture slow evaporation made in Exocarpium Citri Grandis slowly, under conditions of heat preservation long, avoids the loss of effective component;Sinobambusa yin, return lung,
The heart, liver, stomach meridian, burning point it is low, in combustion with temperature it is continuous increase will having property slightly sweet flavor, slightly cold, function
Clearing heat and stopping vomiting washs phlegm and opens strongly fragrant caulis bambusae in taenian, and has treatment cough with lung heat, dysphoria with smothery sensation vomiting, insomnia of palpitating with fear, stroke and phlegm confusing heart gastropyretic vomiting
Act on caulis bambusae in taenian and have it is sweet in flavor and cold in property, can the bamboo juice of clearing heat and eliminating phlegm, relieving convulsion sharp key be clinically usually used in treating apoplexy, high fever, lung
The bamboo juice of diseases such as scorching, frightened epilepsy and tracheitis and have sweet in flavor and cold in property, has the effects that the bamboo that clearing heat and eliminating phlegm, the cool heart are calmed the frightened
Huang, tool " book on Chinese herbal medicine is looked for the truth " carry: " tabasheer and bamboo juice function are slightly same, all can be by phlegm benefit key, but this cool heart goes wind except heat, and it is frightened to control children
Epilepsy wind-heat, phlegm gush aphonia.Compared with bamboo juice, property is gentle, and without cold sliding trouble." be usually used in treating pyreticosis coma, middle wind phlegm
Heap soil or fertilizer over and around the roots, epilepsy, child convulsion twitch etc. diseases and have cold in nature, slightly sweet flavor, with clearing heat and relieving fidgetness, diuresis the leaf of bamboo, " Sheng Hui
It is introduced in just ", being cooked gruel with the leaf of bamboo, it is absent-minded to control children;Clinically it is commonly used to the flourishing caused habituation for the treatment of internal heat just
Secret, hypertension, hemorrhoid, aphthae illness, it is continuous that these effects of bamboo with the continuous raising of temperature are sublimed into gas
Penetrate into the inside of Exocarpium Citri Grandis fruit with enhance the moistening lung for removing phlegm of Exocarpium Citri Grandis, stomach strengthening and digestion promoting, cough-relieving, dispelling wind and removing obstruction in the meridians, tranquilizing and allaying excitement,
Pleasant relieve stagnation and other effects and effect;Mulberry belongs to yin, has wind-damp dispelling, Hang Shui, degrading the channel benefit joint, enters liver kidney, controls wind-cold-dampness arthralgia,
Spasm of limbs, beriberi edema, human body pruritus etc. as the temperature rises distil itself this effective component in combustion
The inside of Exocarpium Citri Grandis fruit is penetrated into for gas to enhance the wet effect of the thin water pouring of the easypro warp of the dredging collateral of Exocarpium Citri Grandis, protect liver benefit kidney;
Root of phragmites communis enters lung channel, is apt to clear lung heat, is apt to control pyreticosis and polydipsia.Cough with lung heat is controlled in the resolving sputum of reed root function reducing fever and causing diuresis relieving cough and moistening lung,
Lung carbuncle pyemesis, in combustion as constantly increasing for temperature is sublimed into gas and penetrates into inside Exocarpium Citri Grandis fruit with enhancingization
The effect of the clearing heat and detoxicating of Exocarpium Citri Rubrum, moistening lung for removing phlegm, protect liver solution polydipsia;Chinese scholartree branch belongs to negative return heart Liver Channel, has dissipating stasis and stanching bleeding, heat-clearing dry
The effect of wet, wind dispelling insecticide, Chinese scholartree branch distil with the continuous raising of temperature in combustion and penetrate into Exocarpium Citri Grandis for gas
Inside fruit with enhance the activating microcirculation and removing stasis medicinal of Exocarpium Citri Grandis, heat-clearing and damp-drying drug, the wind dispelling insecticide for promoting liver and dispelling wind solution in the effect of;Withy
Cold in nature, bitter returns stomach meridian, Liver Channel.It is penetrating into of gas that withy distils with the continuous raising of temperature in combustion
Enhance the expelling wind and removing dampness of Exocarpium Citri Grandis inside Exocarpium Citri Rubrum fruit, the effect of removing toxicity for detumescence, clearing damp and promoting diuresis with effect;By bamboo, ramulus mori,
Chinese scholartree branch, withy, reed root and withy in combustion process with the their own effective component of constantly raising of temperature with temperature and
Time constantly increase and extend and distil generate gas constantly penetrate into Exocarpium Citri Grandis fruit inside make Exocarpium Citri Grandis it is effective at
Point a kind of natural merge and keep the effective component of Exocarpium Citri Grandis constantly to agglomerate enhancing, make Exocarpium Citri Grandis itself with them
Moisture is slowly reduced, the various effective components of Exocarpium Citri Grandis further reach highest content;Making Exocarpium Citri Grandis further has to enhance
Stomach strengthening and digestion promoting, protect liver, wind-dispelling be calm, clearing heat and detoxicating, clearing damp and promoting diuresis, invigorating the spleen to dry, sharp water conservancy are wet, swelling and pain relieving, tranquilizing the mind, solution
Convulsion, chest distress and palpitation symptoms, moistening lung, resolving sputum, yin-nourishing heat-clearing, dispersing stagnated hepatoqi, it is clearing heat and detoxicating, open width of chest gas, channels sootheing and network vessel quickening, invigorating the spleen to dry,
Spleen and liver, solution are supported in dissipating bind, prevention and anticancer and other effects;Exocarpium Citri Grandis dress crock is set and is stored 3 years or more at shady and cool ventilation drying;
Exocarpium Citri Grandis acrid, bitter, warm, return lung the spleen channel, tool cold dispelling, eliminating dampness, sharp gas, dissolving phlegm function are used for cough due to wind-cold evil, and larynx is itched abundant expectoration, dyspepsia
Get sick from drinking too much wine, evil of vomitting ruffian it is bored;Old Exocarpium Citri Grandis main ingredient is flavanone and aurantiin, but also containing class element mutually dai etc. effectively at
Point, not only relieving cough and reducing sputum effect is magical, and more valuable is highlighted to the function mystery of human liver's removing toxic substances, health-care hospital effect
Fruit is solely good.
Further, the old honey that the honey is 3 years or more, and the honey is wild scoliid honey.
A kind of preparation method of above-mentioned autumn pear grease, the preparation method packet are provided according to a second aspect of the embodiments of the present invention
Include following steps:
(a) each raw material is weighed according to parts by weight;
(b) autumn pear and pear are peeled stoning respectively, loquat goes to allowance for bark spare with core;
(c) autumn pear, pear, loquat, ginger and lotus root are carried out to pressure juice respectively and collect juice;
(d) Removing Kernel for Date is placed in ceramic pan, then by Exocarpium Citri Grandis, Poria cocos, Radix Ophiopogonis, campanulaceae, Radix Glycyrrhizae, loguat leaf, Huang
Stilbene and water, which are added in ceramic pan, to be decocted, and decoction liquor is collected, then adds water to be decocted into the ceramic pan of the remaining dregs of a decoction, then
Secondary collection decoction liquor, repetition is above-mentioned to add water to be decocted into the ceramic pan of the remaining dregs of a decoction, operation 1-3 times for collecting decoction liquor;
(e) juice of decoction liquor and collection collected after repeatedly decocting is mixed, is decocted, then to adding ice in decoction
Sugar is concentrated, then addition honey and tendril-leaved fritillary bulb powder are boiled, cooled down up to the autumn pear grease into the solution of concentration.
The above method of the present invention can sufficiently extract the effective component in each raw material, and can remove the impurity in honey and
Microorganism is killed, and crushes ferment, can preferably improve the drug effect of preparation autumn pear grease.
Further, in the step (d), decoction, which is specially first boiled by fire, turns small fire decoction 25-35min;It decocts every time
Additive amount to boil water is 6-8 times of Exocarpium Citri Grandis, Poria cocos, Radix Ophiopogonis, campanulaceae, Radix Glycyrrhizae, loguat leaf and Radix Astragali total weight.
Further, in the step (e), decocting to solution relative density is 1.2-1.6;Being concentrated into relative density is
1.8-2.2。
Further, in the step (e), boiling method is first to endure boiling with high heat, then is changed to mild fire, honey to be boiled without
When general foam.
The embodiment of the present invention has the advantages that
(1) autumn is prepared according to specified weight part proportion by selection specified raw material, and according to theory of traditional Chinese medical science in the present invention
Pear syrup, can be under each raw material synergistic effect, so that the autumn pear grease being prepared has, moistening lung to arrest cough, clearing heat and eliminating phlegm, clear away heart-fire profit
Lung promotes appetite, antitussive and expectorant, antitoxic heart-soothing and sedative, sharp intestine and small intestine, clear larynx fall fire, relieving restlessness to quench one's thirst, moisturizes the wind that disappears, removing toxic substances of sobering up, clearly
The effect of lung moistening lung, nourishing the stomach stomach function regulating, has cure rate height, curative effect fast and significant effect cough.
(2) preparation method of the present invention can sufficiently extract the effective component in each raw material, and can remove miscellaneous in honey
Matter and kill microorganism, and ferment is crushed, it can preferably improve the drug effect of preparation autumn pear grease.
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation
Content disclosed by book is understood other advantages and efficacy of the present invention easily, it is clear that described embodiment is the present invention one
Section Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not doing
Every other embodiment obtained under the premise of creative work out, shall fall within the protection scope of the present invention.
The raw material that following embodiment uses is as follows:
Exocarpium Citri Grandis is made by the following method:
The immature Exocarpium Citri Grandis fruit of golden texturing Exocarpium Citri Rubrum is won, is placed in earth kiln and with bamboo, mulberry, reed, ash and willow
Carpentery workshop is that fuel is dried 7 days at 60 DEG C, then by the Exocarpium Citri Grandis fruit merging crock after drying, 3 are stored at shady and cool ventilation
Year obtains Exocarpium Citri Grandis.
Honey: 4 years old wild scoliid honey, it is commercially available to obtain.
Embodiment 1
One, moistening lung to arrest cough autumn pear grease
Above-mentioned moistening lung to arrest cough autumn pear grease is by including that following raw material is made:
5500 parts of autumn pear, 4500 parts of pear, 300 parts of ginger, 1200 parts of lotus root, 400 parts of tendril-leaved fritillary bulb powder, 400 parts of Exocarpium Citri Grandis, Poria cocos
350 parts, 1200 parts of jujube, 1200 parts of loquat, 250 parts of loguat leaf, 600 parts of Radix Ophiopogonis, 250 parts of campanulaceae, 400 parts of Radix Glycyrrhizae, Radix Astragali 300
Part, 1200 parts of rock sugar and 2200 parts of honey.
Two, preparation method
The preparation method of above-mentioned moistening lung to arrest cough autumn pear grease, includes the following steps:
(a) each raw material is weighed according to parts by weight;
(b) autumn pear and pear are peeled stoning respectively, loquat goes to allowance for bark spare with core;
(c) autumn pear, pear, loquat, ginger and lotus root are carried out to pressure juice respectively and collect juice;
(d) Removing Kernel for Date is placed in ceramic pan, then by Exocarpium Citri Grandis, Poria cocos, Radix Ophiopogonis, campanulaceae, Radix Glycyrrhizae, loguat leaf, Huang
Stilbene and water, which are added in ceramic pan, to be decocted, and decoction liquor is collected, then adds water to be decocted into the ceramic pan of the remaining dregs of a decoction, then
Secondary collection decoction liquor, repetition is above-mentioned to add water to be decocted into the ceramic pan of the remaining dregs of a decoction, operation 1 time for collecting decoction liquor,
It is middle to decoct to be first boiled by fire and turning small fire decoction 35min;Decoct every time water additive amount be Exocarpium Citri Grandis, it is Poria cocos, Radix Ophiopogonis, campanulaceae, sweet
8 times of careless, loguat leaf and Radix Astragali total weight;
(e) mixing the juice of the decoction liquor and collection collected after multiple decoct, decocting to solution relative density is 1.6,
It carries out being concentrated into relative density being 2.2 then to rock sugar is added in decoction, then adds honey and tendril-leaved fritillary bulb into the solution of concentration
Powder first endures boiling with high heat, then is changed to mild fire, and honey to be boiled is without general foam, cooling autumn pear grease to obtain the final product.
Experimental example 2
One, moistening lung to arrest cough autumn pear grease
Above-mentioned moistening lung to arrest cough autumn pear grease is by including that following raw material is made:
4500 parts of autumn pear, 5500 parts of pear, 200 parts of ginger, 1800 parts of lotus root, 300 parts of tendril-leaved fritillary bulb powder, 600 parts of Exocarpium Citri Grandis, Poria cocos
250 parts, 800 parts of jujube, 1800 parts of loquat, 350 parts of loguat leaf, 400 parts of Radix Ophiopogonis, 350 parts of campanulaceae, 300 parts of Radix Glycyrrhizae, Radix Astragali 400
Part, 800 parts of rock sugar and 1800 parts of honey.
Two, preparation method
The preparation method of above-mentioned moistening lung to arrest cough autumn pear grease, includes the following steps:
(a) each raw material is weighed according to parts by weight;
(b) autumn pear and pear are peeled stoning respectively, loquat goes to allowance for bark spare with core;
(c) autumn pear, pear, loquat, ginger and lotus root are carried out to pressure juice respectively and collect juice;
(d) Removing Kernel for Date is placed in ceramic pan, then by Exocarpium Citri Grandis, Poria cocos, Radix Ophiopogonis, campanulaceae, Radix Glycyrrhizae, loguat leaf, Huang
Stilbene and water, which are added in ceramic pan, to be decocted, and decoction liquor is collected, then adds water to be decocted into the ceramic pan of the remaining dregs of a decoction, then
Secondary collection decoction liquor, repetition is above-mentioned to add water to be decocted into the ceramic pan of the remaining dregs of a decoction, operation 3 times for collecting decoction liquor,
It is middle to decoct to be first boiled by fire and turning small fire decoction 25min;Decoct every time water additive amount be Exocarpium Citri Grandis, it is Poria cocos, Radix Ophiopogonis, campanulaceae, sweet
6 times of careless, loguat leaf and Radix Astragali total weight;
(e) mixing the juice of the decoction liquor and collection collected after multiple decoct, decocting to solution relative density is 1.2,
It carries out being concentrated into relative density being 1.8 then to rock sugar is added in decoction, then adds honey and tendril-leaved fritillary bulb into the solution of concentration
Powder first endures boiling with high heat, then is changed to mild fire, and honey to be boiled is without general foam, cooling autumn pear grease to obtain the final product.
Experimental example 3
One, moistening lung to arrest cough autumn pear grease
Above-mentioned moistening lung to arrest cough autumn pear grease is by including that following raw material is made:
5000 parts of autumn pear, 5000 parts of pear, 250 parts of ginger, 1500 parts of lotus root, 350 parts of tendril-leaved fritillary bulb powder, 500 parts of Exocarpium Citri Grandis, Poria cocos
300 parts, 1000 parts of jujube, 1500 parts of loquat, 300 parts of loguat leaf, 500 parts of Radix Ophiopogonis, 300 parts of campanulaceae, 350 parts of Radix Glycyrrhizae, Radix Astragali 350
Part, 1000 parts of rock sugar and 2000 parts of honey.
Two, preparation method
The preparation method of above-mentioned moistening lung to arrest cough autumn pear grease, includes the following steps:
(a) each raw material is weighed according to parts by weight;
(b) autumn pear and pear are peeled stoning respectively, loquat goes to allowance for bark spare with core;
(c) autumn pear, pear, loquat, ginger and lotus root are carried out to pressure juice respectively and collect juice;
(d) Removing Kernel for Date is placed in ceramic pan, then by Exocarpium Citri Grandis, Poria cocos, Radix Ophiopogonis, campanulaceae, Radix Glycyrrhizae, loguat leaf, Huang
Stilbene and water, which are added in ceramic pan, to be decocted, and decoction liquor is collected, then adds water to be decocted into the ceramic pan of the remaining dregs of a decoction, then
Secondary collection decoction liquor, repetition is above-mentioned to add water to be decocted into the ceramic pan of the remaining dregs of a decoction, operation 2 times for collecting decoction liquor,
It is middle to decoct to be first boiled by fire and turning small fire decoction 30min;Decoct every time water additive amount be Exocarpium Citri Grandis, it is Poria cocos, Radix Ophiopogonis, campanulaceae, sweet
7 times of careless, loguat leaf and Radix Astragali total weight;
(e) mixing the juice of the decoction liquor and collection collected after multiple decoct, decocting to solution relative density is 1.5,
It carries out being concentrated into relative density being 2 then to rock sugar is added in decoction, then adds honey and tendril-leaved fritillary bulb powder into the solution of concentration,
Boiling is first endured with high heat, then is changed to mild fire, and honey to be boiled is without general foam, cooling autumn pear grease to obtain the final product.
Reference examples 1
This reference examples is a kind of moistening lung to arrest cough autumn pear grease, the moistening lung to arrest cough autumn in the moistening lung to arrest cough autumn pear grease and embodiment 3
Pear syrup is essentially identical, and difference is only that the bulbus fritillariae cirrhosae that Exocarpium Citri Grandis is replaced with to same number;The preparation of the moistening lung to arrest cough autumn pear grease
Method is the same as the preparation method in embodiment 3.
Reference examples 2
This reference examples is a kind of moistening lung to arrest cough autumn pear grease, the moistening lung to arrest cough autumn in the moistening lung to arrest cough autumn pear grease and embodiment 3
Pear syrup is essentially identical, and difference is only that the Radix Ophiopogonis that campanulaceae is replaced with to same number;The preparation method of the moistening lung to arrest cough autumn pear grease
With the preparation method in embodiment 3.
Experimental example 1
60 cough patients are chosen, the age is 5-32 years old, is randomly divided into five groups, every group of 20 people;
First group of patient takes the middle moistening lung to arrest cough autumn pear grease of embodiment 3;The moistening lung that second group of patient takes reference examples 1 stops
Cough autumn pear grease;Third group patient takes the moistening lung to arrest cough autumn pear grease of reference examples 2.
Instructions of taking: three times a day, 1 soup ladle is melted with warm water every time is taken or is swallowed slowly containing being melted in mouth with body fluid
Under, it persistently takes 20 days, other therapeutic agents is cut out during treatment;
Judgment criteria:
(1) effective: clinical symptoms completely disappear, and cut in later six months of being discontinued and do not recur;
(2) effectively: substantially reduced or clinical symptoms of coughing completely disappear but recurrence in half a year;
(3) invalid: clinical symptoms are not improved or aggravate.
Each embodiment of table 1 and reference examples health-care efficacy testing result
Group | Effective (people) | Effectively (people) | (people) in vain |
First group | 6 | 13 | 1 |
Second group | 1 | 15 | 4 |
Third group | 2 | 12 | 6 |
As shown in Table 1:
The moistening lung to arrest cough autumn pear grease that the embodiment of the present invention and reference examples are prepared all has certain curative effect to treatment cough,
The therapeutic effect for the moistening lung to arrest cough autumn pear grease that embodiment is prepared is significantly higher than control group.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.
Claims (10)
1. a kind of moistening lung to arrest cough autumn pear grease, which is characterized in that by including that following raw material is made:
4500-5500 parts of autumn pear, 4500-5500 parts of pear, 200-300 parts of ginger, 1200-1800 parts of lotus root, tendril-leaved fritillary bulb powder 300-400
Part, 400-600 parts of Exocarpium Citri Grandis, 250-350 parts of Poria cocos, 800-1200 parts of jujube, 1200-1800 parts of loquat, loguat leaf 250-350
Part, Radix Ophiopogonis 400-600 part, 250-350 parts of campanulaceae, 300-400 parts of Radix Glycyrrhizae, 300-400 parts of Radix Astragali and 1800-2200 parts of honey.
2. autumn pear grease according to claim 1, which is characterized in that the raw material further includes 800-1200 parts of rock sugar.
3. autumn pear grease according to claim 1 or 2, which is characterized in that by including that following raw material is made:
5000 parts of autumn pear, 5000 parts of pear, 250 parts of ginger, 1500 parts of lotus root, 350 parts of tendril-leaved fritillary bulb powder, 500 parts of Exocarpium Citri Grandis, Poria cocos 300
Part, 1000 parts of jujube, 1500 parts of loquat, 300 parts of loguat leaf, 500 parts of Radix Ophiopogonis, 300 parts of campanulaceae, 350 parts of Radix Glycyrrhizae, 350 parts of Radix Astragali
With 2000 parts of honey.
4. autumn pear grease according to claim 1 or 2, which is characterized in that the Exocarpium Citri Grandis is prepared via a method which to obtain:
The immature Exocarpium Citri Grandis fruit of golden texturing Exocarpium Citri Rubrum is won, is placed in earth kiln and with bamboo, mulberry, reed, ash and willow work
Low temperature drying is carried out for fuel to get the Exocarpium Citri Grandis.
5. autumn pear grease according to claim 4, which is characterized in that the low temperature drying temperature is 50-60 DEG C;Time is 6-
8 days.
6. autumn pear grease according to claim 1 or 2, which is characterized in that the old honey that the honey is 3 years or more, and
The honey is wild scoliid honey.
7. the preparation method of any autumn pear grease of claim 1-6, which comprises the steps of:
(a) each raw material is weighed according to parts by weight;
(b) autumn pear and pear are peeled stoning respectively, loquat goes to allowance for bark spare with core;
(c) autumn pear, pear, loquat, ginger and lotus root are carried out to pressure juice respectively and collect juice;
(d) by Removing Kernel for Date be placed in ceramic pan in, then by Exocarpium Citri Grandis, Poria cocos, Radix Ophiopogonis, campanulaceae, Radix Glycyrrhizae, loguat leaf, Radix Astragali and
Water is added in ceramic pan and is decocted, and collects decoction liquor, then adds water to be decocted into the ceramic pan of the remaining dregs of a decoction, receives again
Collect decoction liquor, repetition is above-mentioned to add water to be decocted into the ceramic pan of the remaining dregs of a decoction, operation 1-3 times for collecting decoction liquor;
(e) juice of decoction liquor and collection collected after repeatedly decocting is mixed, is decocted, then to added in decoction rock sugar into
Row concentration, then addition honey and tendril-leaved fritillary bulb powder are boiled, are cooled down up to the autumn pear grease into the solution of concentration.
8. preparation method according to claim 7, which is characterized in that in the step (d), decocting is specially that first high fire is boiled
It opens and turns small fire decoction 25-35min;Decocting water additive amount every time is Exocarpium Citri Grandis, Poria cocos, Radix Ophiopogonis, campanulaceae, Radix Glycyrrhizae, loguat leaf and Huang
6-8 times of stilbene total weight.
9. preparation method according to claim 7, which is characterized in that in the step (e), decoct to solution relative density
For 1.2-1.6;Being concentrated into relative density is 1.8-2.2.
10. preparation method according to claim 7, which is characterized in that in the step (e), boiling method is first to use force
Fire endures boiling, then is changed to mild fire, when boiling honey without general foam.
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Cited By (6)
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CN111264857A (en) * | 2020-03-17 | 2020-06-12 | 中科花鹿农业发展有限公司 | Multifunctional Huai ginger paste and preparation method thereof |
CN112772881A (en) * | 2021-01-08 | 2021-05-11 | 威宁彝族回族苗族自治县果业发展中心 | Production process of cough-relieving and phlegm-reducing yellow pear syrup |
CN113040353A (en) * | 2021-04-06 | 2021-06-29 | 广东绿健源健康产业科技有限公司 | Production process of dried orange peel and autumn pear concentrated paste |
CN113951510A (en) * | 2021-02-19 | 2022-01-21 | 北京鹤年堂中医医院管理(集团)有限公司 | Snow pear paste and preparation method thereof |
CN114098031A (en) * | 2021-11-19 | 2022-03-01 | 北京市临床药学研究所(北京市中药研究所) | Fine astragalus and autumn pear paste and preparation method thereof |
CN114568694A (en) * | 2022-03-06 | 2022-06-03 | 朱云兰 | Loquat leaf extract and preparation method thereof |
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CN103392852A (en) * | 2013-06-25 | 2013-11-20 | 安徽翠兰投资发展有限公司 | Throat protecting and phlegm eliminating snow pear tea and preparation method thereof |
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CN103392852A (en) * | 2013-06-25 | 2013-11-20 | 安徽翠兰投资发展有限公司 | Throat protecting and phlegm eliminating snow pear tea and preparation method thereof |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN111264857A (en) * | 2020-03-17 | 2020-06-12 | 中科花鹿农业发展有限公司 | Multifunctional Huai ginger paste and preparation method thereof |
CN112772881A (en) * | 2021-01-08 | 2021-05-11 | 威宁彝族回族苗族自治县果业发展中心 | Production process of cough-relieving and phlegm-reducing yellow pear syrup |
CN113951510A (en) * | 2021-02-19 | 2022-01-21 | 北京鹤年堂中医医院管理(集团)有限公司 | Snow pear paste and preparation method thereof |
CN113040353A (en) * | 2021-04-06 | 2021-06-29 | 广东绿健源健康产业科技有限公司 | Production process of dried orange peel and autumn pear concentrated paste |
CN114098031A (en) * | 2021-11-19 | 2022-03-01 | 北京市临床药学研究所(北京市中药研究所) | Fine astragalus and autumn pear paste and preparation method thereof |
CN114568694A (en) * | 2022-03-06 | 2022-06-03 | 朱云兰 | Loquat leaf extract and preparation method thereof |
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