CN110123733A - A kind of fullerene Essence and preparation method thereof - Google Patents

A kind of fullerene Essence and preparation method thereof Download PDF

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Publication number
CN110123733A
CN110123733A CN201910393531.4A CN201910393531A CN110123733A CN 110123733 A CN110123733 A CN 110123733A CN 201910393531 A CN201910393531 A CN 201910393531A CN 110123733 A CN110123733 A CN 110123733A
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weight
parts
fullerene
skin
essence
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肖夏旭
易黎明
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Guangzhou Li Li Cosmetics Biotechnology Co Ltd
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Guangzhou Li Li Cosmetics Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Dermatology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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  • Cosmetics (AREA)

Abstract

The invention belongs to cosmetic technical fields, and in particular to a kind of fullerene Essence and preparation method thereof.Fullerene Essence of the present invention is by NSKIN NG functional component, pyrenomycetes (SCLEROTIUM ROLFSSII) glue, glycerol, parahydroxyacet-ophenone, 1, 2- hexylene glycol, 1, 2- pentanediol, water-soluble fullerene, ceramide functional component, Bacillus acidi lactici/bear's weed tunning extract, carnosine, lactobacillus fermentation lysate, deionized water is prepared by rational proportion, nutriment abundant is provided for skin, it is used for a long time, to colour of skin unevenness, dry skin, the skin problems such as aged skin have apparent reverse and repair function, and the skin revitalization health status after improving effectively can be kept from root.

Description

A kind of fullerene Essence and preparation method thereof
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of fullerene Essence and preparation method thereof.
Background technique
Fullerene (Fullerene) is the third allotrope that simple substance carbon is found, be find so far it is unique It is dissolved in the isomer of the carbon of Conventional solvents at room temperature.
Fullerene in skin anti-aging, promotes the fields such as hair follicle growth to play master as a kind of extremely strong polyphenoils It acts on.Fullerene is to solve the problems, such as the most effective ingredient of skin free radical at present, it has overturned free radical revolution, anti-oxidant Ability is 172 times of Vitamin C, and white-skinned face function is ascorbic 100 times.But at present still without a kind of with excellent moisturizing Whitening and anti-aging, the fullerene Essence for being beneficial to skin texture and reconstruction again simultaneously.
The main component of NSKIN NG is acrylic acid (ester) analog copolymer sodium, and thickener, moisturizer are played in cosmetics Effect.
Pyrenomycetes (SCLEROTIUM ROLFSSII) glue is the natural polymer of polysaccharide, scleroglucan is also, in high temperature And it is all very stable under a variety of pH value, and be polysaccharide polymer, it is good with skin-friendliness, it can effectively form a film, and stability is good.
Glycerol is the colourless sweet clear and bright thick liquid of food-grade, odorless, has warm sweet taste, can be used as solvent, lubricant, medicament And sweetener.
Parahydroxyacet-ophenone is widely used in medicine, cosmetics, industrial circle, is a kind of natural plant extracts, naturally It is present in the roots of plants such as stem, leaf, Artemisia capillaris, Asclepiadaceae plant, the kerr tylophora root of compositae plant artemisia scoparia, has anti-oxidant With the effect of releiving, it in cosmetics, can be used as the substitute of traditional preservatives, have the function of anti-corrosion synergy, can promote each Kind preservative efficacy, there is excellent stability in biggish pH and temperature range.
1,2- hexylene glycol is moisturizer, belongs to polyalcohol, has fungistatic effect, only just when additive amount is 5% or so There is anti-corrosion effect, but is not equal to preservative.
1,2- pentanediol belongs to small molecule moisturizer, is a kind of synthesis moisturizer, makees in cosmetics and beauty product molten Agent and preservative use, and have water lock and antibacterial functions, and can improve the water-resistance of sunscreen product, but the ingredient has slightly eyes Stimulation, it is non-stimulated to skin.
Water-soluble fullerene can affine free radical, have extremely strong oxidation resistance, activating skin cells can be played, The effect of delaying skin apoptosis, current study show that pure fullerene be it is nontoxic, property is mild safely.
For Caesalpinia spinosaKuntze (CAESALPINIA SPINOSA) glue using Caesalpinia spinosaKuntze as waste, main component is a kind of neutral Galactomannans can be cooked thickener, stabilizer and film forming agent and be used, adjust the organoleptic quality of product, safe to the human body, nontoxic Side effect;Cer NP is a kind of lipid matter, and artificial synthesized ingredient, it is close with the structure of matter of keratoderma is constituted, It can penetrate into skin quickly, help the update of skin natural containment, in the balance and cuticula that nature aquation can be promoted Water combine, form a kind of reticular structure, lock moisture, have good action to skin moisturizing maintenance, be important in cuticula Skin-active ingredient, can enhance skin barrier, and reconstituted cell forms effective barrier to prevent water loss and reduce external environment It influences.The especially needed more ceramides of stimulated skin, some researches show that wipe the product energy containing ceramide ingredient Red and swollen and percutaneous water loss is reduced, play the role of enhancing skin barrier and impaired skin is helped to alleviate drying regime.
Bacillus acidi lactici/bear's weed tunning extract has good moisturizing, lubricates and performance of releiving, it is also possible to make skin Feel modifying agent, keeps skin emolliency smooth.
Carnosine is not only nutritional agents, while can promote the metabolism of cell again, delays senescence, as more in medicinal cream Hurt promotor;Carnosine can capture free oxygen radical, be effectively prevented the oxidation of Protein components, brighten function;With urine Periodical acid, which shares, can prevent photosensitive dermatitis;Carnosine is also easily skin, hair and scalp absorb, and helps infiltration effect.
Lactobacillus fermentation lysate includes thallus and the whole active constituents synthesized during the fermentation, poly- containing peptide Sugar, teichoic acid, protein, phosphatide, sterol, fatty acid, various enzymes, peptide and amino acid, nucleotide, exocellular polysaccharide etc. are flesh Skin provides abundant nutrition, has good anti-aging effects.
Summary of the invention
The object of the present invention is to provide a kind of fullerene Essences and preparation method thereof.Fullerene Essence of the present invention by NSKIN NG functional component, pyrenomycetes (SCLEROTIUM ROLFSSII) glue, glycerol, parahydroxyacet-ophenone, 1,2- hexylene glycol, 1,2- pentanediol, water-soluble fullerene, ceramide functional component, Bacillus acidi lactici/bear's weed tunning extract, flesh Peptide, lactobacillus fermentation lysate, deionized water are prepared by rational proportion, provide nutrients abundant for skin Matter is used for a long time, and has apparent reverse and repair function, and energy to the skin problems such as colour of skin unevenness, dry skin, aged skin Effectively the skin revitalization health status after improving is kept from root.
The technical solution of the present invention is as follows:
A kind of preparation method of fullerene Essence, comprising the following steps:
(1) 0.2~0.3 parts by weight NSKIN NG functional component, 0.1~0.2 parts by weight pyrenomycetes (SCLEROTIUM are taken ROLFSSII) glue, 81.6~90.6 parts by weight of deionized water are heated with stirring to 95 DEG C in emulsion pot, and homogeneous is complete;
(2) 2~5 parts by weight of glycerin, 0.5~0.8 parts by weight parahydroxyacet-ophenone are taken to be heated with stirring to 60 DEG C, dissolution is complete After be added into emulsion pot, start to cool down after mixing evenly;
(3) it is down to room temperature to temperature, takes 0.5~0.8 parts by weight 1,2- hexylene glycol, 0.5~1 parts by weight 1,2- pentanediol, 0.5~1 parts by weight water-soluble fullerene, 2~4 parts by weight ceramide functional components, 2~4 parts by weight Bacillus acidi lacticis/North America are holy Careless tunning extract, 0.1~0.2 parts by weight carnosine, 1~2 parts by weight lactobacillus fermentation lysis object product are added to cream Change in pot, obtains fullerene Essence after mixing evenly.
Further, the NSKIN NG functional component includes acrylic acid (ester) analog copolymer sodium and marine algae extract.
Further, the ceramide functional component includes water, glycerol, tara gum and Cer NP.
The fullerene Essence that the above method is prepared.
Beneficial effects of the present invention are as follows:
1, the moisturising actives such as Bacillus acidi lactici/bear's weed tunning extract, ceramide can enhance skin screen Barrier, reconstituted cell form effective barrier to prevent water loss and reduce the influence of external environment, and carnosine has centainly skin Whitening efficacy so that fullerene Essence of the present invention have good moisturizing whitening effect;
2, fullerene oxidation resistance is 170 times of Victoria C, it can be good at affine free radical, has extremely strong antioxygen Change ability, plays the role of activating skin cells, prevention skin decline, by with NSKIN NG functional component, pyrenomycetes (SCLEROTIUM ROLFSSII) glue, glycerol, parahydroxyacet-ophenone, 1,2- hexylene glycol, 1,2- pentanediol, ceramide function The conjunction of ingredient, Bacillus acidi lactici/bear's weed tunning extract, carnosine, lactobacillus fermentation lysate and deionized water Reason proportion enables fullerene Essence of the present invention effectively delay senescence, be effectively improved wrinkle, be obscure, color spot, the fleshes such as drying Skin problem;
3, fullerene Essence of the present invention is suitable for any skin quality.
Specific embodiment
With reference to embodiment, technical solution of the present invention is described in further detail, but do not constituted pair Any restrictions of the invention.
Embodiment 1
A kind of preparation method of fullerene Essence, comprising the following steps:
(1) 0.2 parts by weight NSKIN NG functional component, 0.15 parts by weight pyrenomycetes (SCLEROTIUM ROLFSSII) are taken Glue, 81.9 parts by weight of deionized water are heated with stirring to 95 DEG C in emulsion pot, and homogeneous is complete;
(2) it takes 3 parts by weight of glycerin, 0.6 parts by weight parahydroxyacet-ophenone to be heated with stirring to 60 DEG C, is added extremely after dissolving completely In emulsion pot, start to cool down after mixing evenly;
(3) it is down to room temperature to temperature, takes 0.5 parts by weight 1,2- hexylene glycol, 0.8 parts by weight 1,2- pentanediol, 0.6 parts by weight Water-soluble fullerene, 3 parts by weight ceramide functional components, 2 parts by weight Bacillus acidi lacticis/bear's weed tunning extract, 0.15 parts by weight carnosine, 2 parts by weight lactobacillus fermentation lysis object products are added into emulsion pot, obtain richness after mixing evenly Strangle alkene Essence.
Wherein, the NSKIN NG functional component includes acrylic acid (ester) analog copolymer sodium, marine algae extract;The nerve Amide functional component includes water, glycerol, tara gum, Cer NP;The lactobacillus fermentation lysate components include bacterium Body, peptide glycan, teichoic acid, protein, phosphatide, sterol, fatty acid, various enzymes, peptide and amino acid, nucleotide, exocellular polysaccharide.
The fullerene Essence that the present embodiment is prepared has good moisturizing whitening effect;Can effectively it delay simultaneously Aging is effectively improved wrinkle, is obscure, color spot, the skin problem such as drying;And it is suitable for any skin quality.
Embodiment 2
A kind of preparation method of fullerene Essence, comprising the following steps:
(1) 0.3 parts by weight NSKIN NG functional component, 0.15 parts by weight pyrenomycetes (SCLEROTIUM ROLFSSII) are taken Glue, 85 parts by weight of deionized water are heated with stirring to 95 DEG C in emulsion pot, and homogeneous is complete;
(2) it takes 2 parts by weight of glycerin, 0.8 parts by weight parahydroxyacet-ophenone to be heated with stirring to 60 DEG C, is added extremely after dissolving completely In emulsion pot, start to cool down after mixing evenly;
(3) it is down to room temperature to temperature, takes 0.6 parts by weight 1,2- hexylene glycol, 0.8 parts by weight 1,2- pentanediol, 0.5 parts by weight Water-soluble fullerene, 3 parts by weight ceramide functional components, 3 parts by weight Bacillus acidi lacticis/bear's weed tunning extract, 0.1 parts by weight carnosine, 2 parts by weight lactobacillus fermentation lysis object products are added into emulsion pot, obtain richness after mixing evenly Strangle alkene Essence.
Wherein, the NSKIN NG functional component includes acrylic acid (ester) analog copolymer sodium, marine algae extract;The nerve Amide functional component includes water, glycerol, tara gum, Cer NP;The lactobacillus fermentation lysate components include bacterium Body, peptide glycan, teichoic acid, protein, phosphatide, sterol, fatty acid, various enzymes, peptide and amino acid, nucleotide, exocellular polysaccharide.
The fullerene Essence that the present embodiment is prepared has good moisturizing whitening effect;Can effectively it delay simultaneously Aging is effectively improved wrinkle, is obscure, color spot, the skin problem such as drying;And it is suitable for any skin quality.
Embodiment 3
A kind of preparation method of fullerene Essence, comprising the following steps:
(1) 0.2 parts by weight NSKIN NG functional component, 0.2 parts by weight pyrenomycetes (SCLEROTIUM ROLFSSII) are taken Glue, 90.5 parts by weight of deionized water are heated with stirring to 95 DEG C in emulsion pot, and homogeneous is complete;
(2) it takes 3 parts by weight of glycerin, 0.8 parts by weight parahydroxyacet-ophenone to be heated with stirring to 60 DEG C, is added extremely after dissolving completely In emulsion pot, start to cool down after mixing evenly;
(3) it is down to room temperature to temperature, takes 0.8 parts by weight 1,2- hexylene glycol, 1 parts by weight 1,2- pentanediol, 0.6 parts by weight water Dissolubility fullerene, 4 parts by weight ceramide functional components, 2 parts by weight Bacillus acidi lacticis/bear's weed tunning extract, 0.2 Parts by weight carnosine, 1 parts by weight lactobacillus fermentation lysis object product are added into emulsion pot, obtain fullerene after mixing evenly Essence.
Wherein, the NSKIN NG functional component includes acrylic acid (ester) analog copolymer sodium, marine algae extract;The nerve Amide functional component includes water, glycerol, tara gum, Cer NP;The lactobacillus fermentation lysate components include bacterium Body, peptide glycan, teichoic acid, protein, phosphatide, sterol, fatty acid, various enzymes, peptide and amino acid, nucleotide, exocellular polysaccharide.
The fullerene Essence that the present embodiment is prepared has good moisturizing whitening effect;Can effectively it delay simultaneously Aging is effectively improved wrinkle, is obscure, color spot, the skin problem such as drying;And it is suitable for any skin quality.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention, It should be equivalent substitute mode, be included within the scope of the present invention.

Claims (4)

1. a kind of preparation method of fullerene Essence, which comprises the following steps:
(1) 0.2~0.3 parts by weight NSKIN NG functional component, 0.1~0.2 parts by weight Scleroglucan, 81.6~90.6 weight are taken Part deionized water is heated with stirring to 95 DEG C in emulsion pot, and homogeneous is complete;
(2) it takes 2~5 parts by weight of glycerin, 0.5~0.8 parts by weight parahydroxyacet-ophenone to be heated with stirring to 60 DEG C, adds after dissolving completely Enter into emulsion pot, starts to cool down after mixing evenly;
(3) it is down to room temperature to temperature, takes 0.5~0.8 parts by weight 1,2- hexylene glycol, 0.5~1 parts by weight 1,2- pentanediol, 0.5~ 1 parts by weight water-soluble fullerene, 2~4 parts by weight ceramide functional components, 2~4 parts by weight Bacillus acidi lacticis/bear's weed hair Ferment product extract, 0.1~0.2 parts by weight carnosine, 1~2 parts by weight lactobacillus fermentation lysis object product are added to emulsion pot In, fullerene Essence is obtained after mixing evenly.
2. a kind of preparation method of fullerene Essence according to claim 1, which is characterized in that the NSKIN NG function Energy ingredient includes acrylic acid (ester) analog copolymer sodium and marine algae extract.
3. a kind of preparation method of fullerene Essence according to claim 1, which is characterized in that the ceramide function Energy ingredient includes water, glycerol, tara gum and Cer NP.
4. the fullerene Essence that any method described in claims 1 to 3 is prepared.
CN201910393531.4A 2019-05-13 2019-05-13 A kind of fullerene Essence and preparation method thereof Pending CN110123733A (en)

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Cited By (4)

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CN110403872A (en) * 2019-08-29 2019-11-05 湖北省麦诗特生物科技有限公司 A kind of preparation method and application of the bear's weed tunning extract with moisture-keeping efficacy
CN110876686A (en) * 2019-11-22 2020-03-13 广州柏俐臣化妆品科技有限公司 Repairing composition and preparation method thereof
CN110934765A (en) * 2019-11-27 2020-03-31 成都格瑞珂诗生物科技有限公司 Fullerene rejuvenation Zhuyan stock solution and preparation method thereof
CN111419782A (en) * 2020-03-26 2020-07-17 海口楠脂香业有限公司 Small water diversion of agilawood and preparation method thereof

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CN107714519A (en) * 2017-11-01 2018-02-23 陈磊 A kind of Essence containing Composition of Meteorite and preparation method thereof
CN108125852A (en) * 2017-12-29 2018-06-08 广州慈康生物科技有限公司 Extremely strong essence lotion of a kind of water moisture feeling and preparation method thereof
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CN109481322A (en) * 2018-10-10 2019-03-19 广州雷诺生物科技有限公司 A kind of fullerene essence cream
CN109260035A (en) * 2018-11-27 2019-01-25 黄犟兵 Anti-ageing composition of a kind of whitening containing fullerene and preparation method thereof
CN109464288A (en) * 2018-12-06 2019-03-15 上海莎伦巍化学科技有限公司 A kind of fowler ene compositions and the Essence containing the fowler ene compositions
CN109464343A (en) * 2018-12-29 2019-03-15 广州灵润生物科技有限公司 A kind of clear essence cream of the polypeptide containing fullerene

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CN110403872A (en) * 2019-08-29 2019-11-05 湖北省麦诗特生物科技有限公司 A kind of preparation method and application of the bear's weed tunning extract with moisture-keeping efficacy
CN110876686A (en) * 2019-11-22 2020-03-13 广州柏俐臣化妆品科技有限公司 Repairing composition and preparation method thereof
CN110934765A (en) * 2019-11-27 2020-03-31 成都格瑞珂诗生物科技有限公司 Fullerene rejuvenation Zhuyan stock solution and preparation method thereof
CN111419782A (en) * 2020-03-26 2020-07-17 海口楠脂香业有限公司 Small water diversion of agilawood and preparation method thereof

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Application publication date: 20190816