CN110051786B - Black ointment and preparation method thereof - Google Patents

Abstract

The application discloses a black ointment and a preparation method thereof, wherein the black ointment comprises gentian, oldenlandia diffusa, gallnut, centipede, borneol, angelica dahurica, bletilla, pseudo-ginseng, salvia miltiorrhiza and fructus forsythiae. The black ointment can dispel acne, fade acne spots, whiten skin, keep moisture and tender skin, and is remarkable in effect. The preparation method comprises pulverizing radix Gentianae, herba Hedyotidis Diffusae, Galla chinensis, Scolopendra, Borneolum Syntheticum, radix Angelicae Dahuricae, rhizoma Bletillae, Notoginseng radix, Saviae Miltiorrhizae radix and fructus forsythiae into superfine powder by micronizing technology; mixing the pulverized superfine powder in proportion to obtain black ointment. The superfine powder is prepared into the superfine powder with fixed measurement according to the proportion and is matched with a proper amount of medium, and a patient can use the superfine powder only by mixing the superfine powder and the medium uniformly, so that the superfine powder is convenient and easy to operate.

Description

Black ointment and preparation method thereof

Technical Field

The application relates to the technical field of black ointment, and particularly relates to black ointment and a preparation method thereof.

Background

Acne, commonly called as acne in traditional Chinese medicine, is a common disease in clinical dermatology, can be divided into common type, cystic swelling, nodular type and polymeric type acne according to the severity of rash, and is divided into adolescent acne and post-adolescent acne according to age stage. Acne is clinically manifested singly, often with symptoms of acne, inflammatory papules, cysts, nodules and the like, and is usually better at adolescence, usually on face, neck, chest, back, shoulders and upper arms. Some people are abundant and present as papules, blackheads, pustules, abscesses, nodules, cysts and even scars. The clinical symptoms of the acne are different in individual response, the damage degree caused by the acne is also different, and the clinical manifestations are also different. Some people develop only mild acne and some people develop severe cysts, leaving behind hyperpigmentation and scars. The existing medicine for treating acne has poor effect.

Disclosure of Invention

The application aims to provide a black ointment and a preparation method thereof, and aims to solve the problem of poor effect of a medicine for treating acne.

In one aspect, according to embodiments of the present application, there is provided a black ointment comprising gentian, oldenlandia, galla chinensis, centipede, borneol, angelica dahurica, bletilla striata, notoginseng, salvia miltiorrhiza and forsythia.

Further, the black ointment comprises the following components in parts by weight: 20 parts of gentian, 10 parts of oldenlandia diffusa, 20 parts of gallnut, 3 parts of centipede, 2 parts of borneol, 10 parts of angelica dahurica, 10 parts of bletilla striata, 10 parts of pseudo-ginseng, 10 parts of salvia miltiorrhiza and 10 parts of forsythia.

Further, the black ointment also comprises a medium, and the medium comprises vinegar, honey and/or milk.

Further, the medium further comprises baking soda.

In another aspect, according to an embodiment of the present application, there is provided a method for preparing a black paste, including:

pulverizing radix Gentianae, herba Hedyotidis Diffusae, Galla chinensis, Scolopendra, Borneolum Syntheticum, radix Angelicae Dahuricae, rhizoma Bletillae, Notoginseng radix, Saviae Miltiorrhizae radix and fructus forsythiae into superfine powder by micronizing technology;

mixing the pulverized superfine powder in proportion to obtain black ointment.

Further, the method further comprises:

and (3) blending the black ointment with a medium to form paste.

Further, the method further comprises:

preparing gel vinegar;

mixing the black ointment with the gel vinegar.

Further, the step of preparing gel vinegar comprises:

fully mixing the skimmed milk and the vinegar, and filtering with gauze to obtain a solid substance on the gauze;

mixing the solid substance with sodium bicarbonate, and stirring to obtain gel vinegar.

According to the technical scheme, the embodiment of the application provides a black ointment and a preparation method thereof, and the black ointment comprises gentian, spreading hedyotis herb, gallnut, centipede, borneol, angelica dahurica, bletilla striata, pseudo-ginseng, salvia miltiorrhiza and fructus forsythiae. The black ointment can dispel acne, fade acne spots, whiten skin, keep moisture and tender skin, and is remarkable in effect. The preparation method comprises pulverizing radix Gentianae, herba Hedyotidis Diffusae, Galla chinensis, Scolopendra, Borneolum Syntheticum, radix Angelicae Dahuricae, rhizoma Bletillae, Notoginseng radix, Saviae Miltiorrhizae radix and fructus forsythiae into superfine powder by micronizing technology; mixing the pulverized superfine powder in proportion to obtain black ointment. The superfine powder is prepared into the superfine powder with fixed measurement according to the proportion and is matched with a proper amount of medium, and a patient can use the superfine powder only by mixing the superfine powder and the medium uniformly, so that the superfine powder is convenient and easy to operate.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.

Fig. 1 is a flowchart illustrating a method for preparing black paste according to an embodiment of the present application.

Detailed Description

The embodiment of the application provides a black ointment which comprises gentian, oldenlandia diffusa, gallnut, centipede, borneol, angelica dahurica, bletilla striata, pseudo-ginseng, salvia miltiorrhiza and forsythia.

Galla chinensis, sour and astringent in flavor, cold in nature. Has the effects of astringing lung and reducing fire, astringing intestine and checking diarrhea, arresting sweating, stopping bleeding, astringing dampness and healing sore. It is commonly indicated for chronic cough due to lung deficiency, chronic diarrhea and dysentery due to lung heat with phlegm, spontaneous perspiration and night sweat, diabetes, hemafecia and hemorrhoidal bleeding, traumatic hemorrhage, carbuncle, swelling, sore and toxicity, and skin ulceration. (compendium of materia Medica) for treating sore without healing: galla chinensis, baking, grinding, and mixing with vinegar foot.

Wu Gong, pungent and warm to extinguish wind and relieve spasm, unblock collaterals and alleviate pain, counteract toxic pathogen and dissipate nodulation for stirring of liver wind, spasm and convulsion, infantile convulsions and apoplexy

Hemiplegia, tetanus, stubborn rheumatism, migraine, sore and ulcer, scrofula, snake and insect bite. The compendium of materia Medica: infantile convulsion, trismus due to pathogenic wind on the umbilicus, alopecia, sore due to erysipelas, scrofula and snake bite.

Dahurian angelica root, pungent and warm. The functions are mainly used for dispelling wind, eliminating dampness, reducing swelling and relieving pain. It can be used for treating headache, supercilium pain, odontalgia, nasosinusitis, cold-dampness, abdominal pain, intestinal wind, hemorrhoid, leucorrhea with red and white discharge, carbuncle, skin ulcer, pruritus, scabies, and tinea. External use: grind into powder or mix with other herbs for external application. For treating toxic swelling and pain due to heat: vinegar concocting with radix Angelicae Dahuricae is applied topically. (& lt & ltsanitary easy simple prescription)

Bletilla striata, bitter, sweet, astringent and slightly cold. Has the effects of astringing, stopping bleeding, relieving swelling and promoting granulation. Can be used for treating hemoptysis, hematemesis, traumatic hemorrhage, pyocutaneous disease, toxic swelling, and chapped skin. The book Jing: abscess, swelling and sore, abscess and deep-rooted carbuncle, impairment of yin and death of muscles, attack of pathogenic wind in stomach, mild miliaria and no contraction. The materia medica meet original: bai Ji is astringent and astringent in nature, so it can enter lung to stop bleeding, promote tissue regeneration and cure sores because it can get qi of autumn-jin.

Notoginseng radix is used for treating hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, thoracico-abdominal pain, and traumatic swelling and pain. Has the effects of stopping bleeding, removing blood stasis, diminishing inflammation, relieving pain and nourishing, and is a main medicine for treating traumatic injury.

Salvia miltiorrhiza, being bitter in taste, has the effects of promoting blood circulation to remove blood stasis, stimulating the menstrual flow to relieve pain, clearing away the heart-fire and relieving restlessness, cooling blood and eliminating carbuncle. Can be used for treating thoracic obstruction, heart pain, abdominal pain, hypochondriac pain, abdominal mass, pain due to pyretic arthralgia, vexation, insomnia, menoxenia, dysmenorrhea, amenorrhea, and pyocutaneous disease with swelling and pain. (the prescription of the posterior cubital region) with hot oil and fire, pain relieving and granulation promoting: eight or two rasps of salvia miltiorrhiza are taken, fine adjustment is carried out by water, two jin of mutton tallow is taken, three jin are decocted, three yuan are decocted, and the three jin are used for being smeared on sores.

Forsythia fruit, fructus forsythiae is bitter and cool. The book Jing: bitter and mild in taste. The bibliography: is nontoxic. Has the main functions of clearing heat, detoxifying, dissipating stagnation and reducing swelling. It is indicated for warm heat, erysipelas, macula, superficial infection, abscess, swelling, scrofula and stranguria. The book Jing: cold and heat, atrophy of mouse, scrofula, abscess, swelling and sore, goiter and fever. The Li Gao: dispersing all menstrual blood, and collecting qi; and (5) eliminating swelling. It is indicated for scrofula and tuberculosis without disappearing.

Gentian is bitter in taste, cold in nature, clears heat and dries dampness, purges liver and gallbladder fire. It is used to clear heat and dry dampness, purge liver and gallbladder fire. Can be used for treating jaundice due to damp-heat pathogen, pudendal swelling, pudendal pruritus, leukorrhagia, eczema, pruritus, liver fire with conjunctival congestion, tinnitus, deafness, hypochondriac pain, bitter taste in mouth, middle-jiao strengthening, and convulsion. The book of materia Medica: gentiana scabra Bunge, being bitter and cold in nature, has the same actions as Qinlian but its property is retained and moved in the body when its taste is astringent, so it is indicated for bone heat alone; otherwise, clearing away the excessive fire in the liver and gallbladder to dredge the accumulation of damp-heat in the lower-jiao; it is thought that the toxicity of mildew and the superficial infection of cord and stool is rampant of fire, but it is not so bitter and cold enough to purge the flaming flame and it is also the lingering pathogen that drains the lower energizer. Gentian is an oral medicine and can clear heat, dry dampness and purge liver and gallbladder fire. It is used to clear heat and dry dampness, purge liver and gallbladder fire. The external medicine is innovatively used for treating acne through more than ten years of clinical research, has the functions of clearing heat and drying dampness, and can treat eczema and pruritus, so that the external medicine has a good treatment effect on the acne.

The oldenlandia diffusa is mainly used for treating: cough and asthma due to lung heat; swollen and sore throat; intestinal abscess; furuncle, swelling, sore and ulcer; bite by poisonous snake; stranguria with heat manifested as painful urination; edema; dysentery; enteritis; jaundice due to damp-heat; it is good at treating various cancers. External use: pounding and applying.

The borneol has fragrant smell and can promote transdermal absorption.

The treatment of 2016-2018 acne patients was statistically determined and the comparison of the effects of acne treatments is shown in Table 1.

TABLE 1

According to the technical scheme, the embodiment of the application provides a black ointment and a preparation method thereof, and the black ointment comprises gentian, spreading hedyotis herb, gallnut, centipede, borneol, angelica dahurica, bletilla striata, pseudo-ginseng, salvia miltiorrhiza and fructus forsythiae. The black ointment can dispel acne, fade acne spots, whiten skin, keep moisture and tender skin, and is remarkable in effect.

Further, the black ointment comprises the following components in parts by weight: 20 parts of gentian, 10 parts of oldenlandia diffusa, 20 parts of gallnut, 3 parts of centipede, 2 parts of borneol, 10 parts of angelica dahurica, 10 parts of bletilla striata, 10 parts of pseudo-ginseng, 10 parts of salvia miltiorrhiza and 10 parts of forsythia. The black ointment prepared by adopting the proportion has good effect of treating the acne.

Further, the black ointment also comprises a medium, and the medium comprises vinegar, honey and/or milk.

In particular, vinegar was used as a medium during acne and honey milk was used as a medium during recovery.

Further, the medium further comprises baking soda. If the proportion is not proper, the vinegar has the function of astringency, and is tightly stuck to the face after being used, and is difficult to clean. The baking soda, milk and vinegar can be made into gel vinegar, which is convenient for cleaning after use.

The black ointment needs to be powdered by the patient himself, sieved and then used after being mixed according to the medical advice, so that the patient is often not mixed properly, and the use effect is affected.

Referring to fig. 1, an embodiment of the present application provides a method for preparing a black paste, including:

step S1, smashing gentian, oldenlandia diffusa, gallnut, centipede, borneol, angelica dahurica, bletilla striata, pseudo-ginseng, salvia miltiorrhiza and fructus forsythiae into superfine powder by utilizing an ultramicro smashing technology;

the Chinese herbal medicine superfine grinding technology is an update and development of the traditional grinding technology, mainly refers to cell-level superfine grinding, aims at grinding fineness, pursues cell wall breaking rate, enriches the processing content of the traditional Chinese herbal medicine, injects new vitality for modern production, application and development of the Chinese herbal medicine, and can effectively improve the utilization rate of functional substances.

The superfine powder is ground by a small-sized traditional Chinese medicine fine powder grinding machine, the superfine powder is about 200 meshes of powder in national formulary, and the raw materials are ground very finely, so that the dissolving temperature of an active substance can be greatly reduced, and the activity can be maintained. The superfine pulverizing technology is to pulverize various solid substances into powder with diameter less than 10 μm.

The vibration mill is used, and the grinding body is a cylinder body loaded with the grinding body and supported by a spring. A spherical eccentric rotor is arranged in the cylinder and is directly driven by a motor to rotate at high speed (1000-3000 r/min). The inertial centrifugal force makes the cylinder body make high-frequency vibration in vertical and horizontal directions, and the powder material placed between the grinding bodies in the cylinder body is ground under the action of high-frequency impact and grinding of the grinding bodies. If a cylinder is used as the grinding body instead of a round ball, the point contact between the grinding bodies is changed into the line contact, so that the ultra-fine powder with 90 percent passing 1 micron and 50 percent passing 0.4 micron can be obtained.

And step S2, mixing the crushed superfine powder according to a proportion to obtain the black ointment.

Further, the method further comprises:

and (3) blending the black ointment with a medium to form paste.

Further, the method further comprises:

preparing gel vinegar;

mixing the black ointment with the gel vinegar.

Further, the step of preparing gel vinegar comprises:

fully mixing the skimmed milk and the vinegar, and filtering with gauze to obtain a solid substance on the gauze;

mixing the solid substance with sodium bicarbonate, and stirring to obtain gel vinegar.

The specific preparation method of the gel vinegar comprises the following steps:

preparing materials: 40mL of skimmed milk, 10mL of vinegar, gauze, baking soda and 1 transparent cup.

1) 40mL of skim milk was poured into a cup, 10mL of vinegar was added, and the mixture was stirred well.

2) The mixture was filtered through gauze.

3) The solid material collected in the gauze was poured into a cup.

4) Adding a proper amount of baking soda into a cup, stirring, and preparing the gel vinegar.

Vinegar has astringent effect, and can be applied to face tightly and is difficult to clean. The baking soda, milk and vinegar can be made into gel vinegar, which is convenient for cleaning after use.

According to the technical scheme, the embodiment of the application provides a black ointment and a preparation method thereof, and the black ointment comprises gentian, spreading hedyotis herb, gallnut, centipede, borneol, angelica dahurica, bletilla striata, pseudo-ginseng, salvia miltiorrhiza and fructus forsythiae. The black ointment can dispel acne, fade acne spots, whiten skin, keep moisture and tender skin, and is remarkable in effect. The preparation method comprises pulverizing radix Gentianae, herba Hedyotidis Diffusae, Galla chinensis, Scolopendra, Borneolum Syntheticum, radix Angelicae Dahuricae, rhizoma Bletillae, Notoginseng radix, Saviae Miltiorrhizae radix and fructus forsythiae into superfine powder by micronizing technology; mixing the pulverized superfine powder in proportion to obtain black ointment. The superfine powder is prepared into the superfine powder with fixed measurement according to the proportion and is matched with a proper amount of medium, and a patient can use the superfine powder only by mixing the superfine powder and the medium uniformly, so that the superfine powder is convenient and easy to operate.

In order to prove the curative effect of the black ointment provided by the application, the following is a specific case provided by the application.

Medical record one

Yan stand group gender; age of the woman: the 21 year old nationality: han dynasty style toy

Occupation: the student first visit time: 2009.7.17

The main complaints are: facial acne and aggravation of March

The current medical history: the patient feels that facial acne appears in good time and bad, attacks repeatedly, aggravates in the early menstrual period and is accompanied with dry excrement for 2-3 days, the patient prefers to eat spicy, fat, sweet, thick and greasy food, the acne aggravates after eating, the tongue is red, the tongue coating is yellow and greasy, and the pulse is slippery.

Traditional Chinese medicine diagnosis: acne (internal heat of lung channel, stagnant dampness and yang stagnation)

And (3) Western diagnosis: acne

Therapeutic method: clearing and dispersing lung heat, removing dampness and removing blood stasis

The method comprises the following steps: qingfeiyin (oral administration) black ointment (external application)

And (3) return diagnosis: 2009.7.25 the patients with acne have less new hair and normal stool, but more old acne.

Order: the black ointment powder for external use is used for a month and then the patient is diagnosed

And (3) return diagnosis: 2009.12.2

The patient can see a doctor before headache, and the facial acne is cured after the external medicinal powder is used for more than two months.

Medical record 2

Name: qianjiang sex: age of the woman: 16 ethnic groups: han dynasty style toy

Occupation: the student first visit time: 2016.7.6

The main complaints are: facial acne gradually aggravates for more than one year

The current medical history: the patients self-reported that the face gradually suffered from acne after the first tide of 13 years, and the patients started to be obviously aggravated at the age of fifteen, accompanied by pruritus, greasy face, red tongue with yellow coating and wiry pulse.

Traditional Chinese medicine diagnosis: acne (lung meridian internal heat)

And (3) Western diagnosis: acne

Therapeutic method: clearing and ventilating lung heat

The method comprises the following steps: modified Qingfei loquat decoction (oral administration) Black ointment powder (external use)

And (3) return diagnosis: 2016.7.20

After the medicine is taken, the acne is faded for more than ten days after the black ointment is externally used, the itching is not generated, and the acne mark is obvious.

Order: continuously externally used black ointment for two months

2016.9.1

The acne and acne marks on the face are removed and no recurrence occurs because the lung channel diseases come before the treatment.

Medical record III

Name: horse wave property: age of the male: 21 ethnic group: returning to the place: the student first visit time: 2009.12.25

The main complaints are: anti-recurrence of facial acne with two-year pruritus

The current medical history: facial acne appears two years ago without obvious inducing factors, and the acne occurs at most in two cheeks, accompanied by pruritus, intolerance, constipation, self-heat intolerance, accompanied by strong body, pale tongue with white fur and floating pulse.

Traditional Chinese medicine diagnosis: acne (lung meridian internal heat)

And (3) Western diagnosis: acne

Therapeutic method: dispelling wind and clearing heat, promoting blood circulation and resolving hard mass disease, treating acne and removing acne mark

The method comprises the following steps: loquat lung-clearing decoction (oral administration) black ointment powder (external use)

And (3) return diagnosis: 2010.1.6 the patients have reduced face pruritus after administration, and the acne has no new hair, but the acne and acne marks are obvious.

Order: external use black ointment for one month

Three diagnoses: 2010.3.10

Patients have obviously reduced acne without relapse and pruritus, and the black ointment is required to be externally used for whitening.

Medical record four

Name: sex of swan in ginger: age of the male: 23 nationality: returning to the place: the student first visit time: 2011.6.10

The main complaints are: facial acne more than one year

The current medical history: pinsu is good for eating with a fat, sweet and thick taste, oily skin, a little acne appears on forehead before one year, the acne is not treated, after two or three months, the acne grows on cheeks, mandible and neck, the acne is different in size and gradually aggravated, the acne changes like a pustule, and exudates and nodules are accompanied, and halitosis, constipation, yellow urine, red tongue with yellow fur, greasy tongue and smooth pulse are accompanied.

Traditional Chinese medicine diagnosis: acne (accumulated dampness-heat)

And (3) Western diagnosis: acne

Therapeutic method: acne-eliminating mark-removing medicine for external treatment of blood-activating and stagnation-eliminating disease

The method comprises the following steps: xianfang Huoming Yin (oral administration) black ointment powder (external use)

And (3) return diagnosis: 2011.6, 18 patients have reduced itching after administration, and acne has no new hair, but acne and acne mark are obvious.

Order: external use black ointment for one month

Three diagnoses: 2011.76

The patients obviously reduce the self-describing acne, have no recurrence, relieve the itching feeling, fade the acne mark, continue to externally use the black ointment for half a month, and have no recurrence after follow-up visits.

Other embodiments of the present application will be apparent to those skilled in the art from consideration of the specification and practice of the application disclosed herein. This application is intended to cover any variations, uses, or adaptations of the invention following, in general, the principles of the application and including such departures from the present disclosure as come within known or customary practice within the art to which the invention pertains. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the application being indicated by the following claims.

It will be understood that the present application is not limited to the precise arrangements described above and shown in the drawings and that various modifications and changes may be made without departing from the scope thereof. The scope of the application is limited only by the appended claims.

Claims (5)

1. A black ointment for treating acne is characterized by being prepared from the following raw materials, namely, gentian, spreading hedyotis herb, gallnut, centipede, borneol, angelica dahurica, bletilla striata, pseudo-ginseng, salvia miltiorrhiza and forsythia; the black ointment comprises the following raw materials, by weight, 20 parts of gentian, 10 parts of oldenlandia diffusa, 20 parts of gallnut, 3 parts of centipede, 2 parts of borneol, 10 parts of angelica dahurica, 10 parts of bletilla striata, 10 parts of pseudo-ginseng, 10 parts of salvia miltiorrhiza and 10 parts of fructus forsythiae; the black ointment also comprises a medium, wherein the medium comprises vinegar, honey and/or milk.

2. The black paste of claim 1, wherein the medium further comprises baking soda.

3. A method for preparing a black ointment for treating acne as claimed in claim 1, comprising:

pulverizing radix Gentianae, herba Hedyotidis Diffusae, Galla chinensis, Scolopendra, Borneolum Syntheticum, radix Angelicae Dahuricae, rhizoma Bletillae, Notoginseng radix, Saviae Miltiorrhizae radix and fructus forsythiae into superfine powder by micronizing technology;

mixing the pulverized superfine powder in proportion, and blending with medium to obtain paste to obtain black ointment; wherein vinegar is used as a medium during acne, honey is used during recovery, and milk is used as a medium.

4. A method for preparing gel vinegar for treating acne, characterized in that the black paste prepared in claim 3 is mixed with gel vinegar.

5. The method of claim 4, further comprising the step of preparing gel vinegar:

fully mixing the skimmed milk and the vinegar, and filtering with gauze to obtain a solid substance on the gauze;

mixing the solid substance with sodium bicarbonate, and stirring to obtain gel vinegar.

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