CN110037974A - A kind of topical composition and preparation method thereof with skin-care effect - Google Patents
A kind of topical composition and preparation method thereof with skin-care effect Download PDFInfo
- Publication number
- CN110037974A CN110037974A CN201910452590.4A CN201910452590A CN110037974A CN 110037974 A CN110037974 A CN 110037974A CN 201910452590 A CN201910452590 A CN 201910452590A CN 110037974 A CN110037974 A CN 110037974A
- Authority
- CN
- China
- Prior art keywords
- topical composition
- skin
- parts
- moisturizer
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of topical composition and preparation method thereof with skin-care effect, it is using tetrahydro curcumin and Rhizoma Acori Calami extract as active constituent, in addition the preparation that acceptable auxiliary material is prepared in cosmetics, wherein, acceptable auxiliary material in the cosmetics are as follows: moisturizer, thickener, solvent.The present invention also provides the preparation methods of the topical composition.Topical composition of the present invention not only has preferable moisturizing, moisturizing effect, it may have stronger anti-oxidant, anti-aging ability can be obviously improved the symptom of impaired skin, have no toxic side effect, and have stronger practical application value.Stability study shows that topical composition of the present invention has good stability, easy to use, with good application prospect.
Description
Technical field
The invention belongs to tcm fields, and in particular to a kind of with the topical composition of skin-care effect and its preparation side
Method.
Background technique
Skin aging is a progressive physiology course, refers to that skin function Aging damages, prevents skin to body
Shield ability, the decline such as regulating power, thus skin does not adapt to the variation of internal and external environment, color, color, form, texture occurs
Etc. appearances integral status change.The aging of skin is divided into intrinsic aging and extrinsic aging.Intrinsic aging refers to skin
The natural aging increased with the age.Whiteness of skin is shown as, fine wrinkles, flexibility decrease, cutis laxa etc. occurs.It is exogenous old
That changes is main the reason is that light aging caused by solarization.Show as wrinkle, cutis laxa, coarse, Beige color skin
Discoloration, telangiectasis, pigmented spots are formed.
Tetrahydro curcumin (THC) is produced as the most active and main metabolism generated in curcumin in vivo metabolic process
Object is a kind of natural function whitening raw materials, is to be widely used in whitening from the curcumin hydrogenation isolated in turmeric, dispel
Spot, oxidation resistant all kinds of skin care item, in cream, lotion and essence class product.Inhibitory activity to tyrosinase is mainstream
80 times of whitening product arbutin.Currently, the application of THC is common in following several respects.
Tender skin whitening: curcumin is a polyphenol structure, whitening effect with its whitening, crease-resistant, skin makeup, remove freely
Base absorbs ultraviolet light, inhibits tyrosinase ability related.According to Sami Labs Limtied grinding in vitro to tetrahydro curcumin
Study carefully and show: tetrahydro curcumin has multi-functional and the not side effect of sensitization as skin-whitening agents；Tetrahydro curcumin for
Cutaneous pigmentation, senile plaque, freckle and other relevant skin problems can play remarkable effect；Tetrahydro curcumin is to B16F1
The growth of mouse melanoma cells has significant inhibiting effect, and inhibiting effect will much be better than classical whitening agent arbutin,
Show that tetrahydro curcumin can reach the whitening effect of arbutin high concentration in the case where relatively low concentration；Tetrahydro turmeric
Element has significant inhibiting effect (IC to the activity of tyrosinase (key enzyme that melanin is formed)50For 1.77 μ g/ml), and
Much it is better than arbutin (IC50For 33 μ g/ml) and vitamin C (IC50For 9.33 μ g/ml).
Anti-aging: free radical is the principal element for causing skin to cross presenility, excessive free radical can oxidized protein and
Lipid, damages eucaryotic cell structure, and the free radical for removing skin surface can effectively inhibit skin aging.Tetrahydro curcumin contains simultaneously
There are phenolic hydroxyl group and diketone structure, is a kind of natural antioxidant.On the one hand it can inhibit the further generation of free radical, thus
The chain reaction for breaking free radical, blocks its damage to skin and body, on the other hand can also remove some by external factor
The free radical that (ultraviolet light or air pollution) is generated in skin surface, such as nitro free radical, ultra-oxygen anion free radical and hydroxyl
Free radical, to protect skin not by the destruction of free radical.Murugan P etc. uses niacinamide induced diabetic rats model,
Tetrahydro curcumin can significantly improve the intracorporal superoxide dismutase of diabetes rat, catalase, gluathione as the result is shown
Peptide peroxidase, glutathione-S-transferase, reductive glutathione, vitamin C and vitamin E etc. are in liver and kidney
Activity in dirty shows that tetrahydro curcumin has the function of cell membrane damage caused by being protected from lipid peroxidation.Tetrahydro ginger
Flavine has application in Amway Artistry trophocyte regeneration series, to promote the ability of the extraneous damage of skin confrontation.
Sun-proof crease-resistant: Shiseido company has found face because the mechanism of wrinkle occurs in ultraviolet light and uses curcumin, opens
Send out the medicament " Radix Curcumae essence " for successfully inhibiting to be formed wrinkle.The scientific research personnel in the said firm research center has found after study, skin because
Ultraviolet light irradiation, which generates fold, is worked by means of the gelatinase in skin.This enzyme decomposed to skin with gloss and
The fibre compositions such as the collagen and elasticin of elasticity.The said firm combines the research knot set up with medical university, Harvard, the U.S.
The result of study of structure also confirms that, is that ultraviolet light works in the gene to gelatinase.Scientific research personnel finds suppression from nature
The zingiberaceous plant Radix Curcumae that the active material result discovery of gelatinase processed originates in Southeast Asia is more effective, and is therefrom extracted
" Radix Curcumae essence ", main component is the distinctive curcumin of this plant.The researcher of the Thai Government pharmacy mechanism was by 3 years
Effort, the beautifying use of turmeric is developed using nanotechnology --- anti-aging face cream is made with turmeric.Since turmeric has beauty
White, crease-resistant, skin makeup and antibacterial action are thus beneficial to protect skin.Especially curcuminoids contained in turmeric have very strong
Anti-inflammatory performance, skin effect are fine.But its buff color makes it be not suitable for external application again.By more than 40 researcher 3 years
Tackling key problem, overcome this disadvantage finally, be successfully made skin care item.It is reported that this face cream is rich in the herbal medicine that Bangkok is held
As soon as looking at upper can emerge, the favor by customer.
With the development of science and technology with the continuous improvement of living standards of the people, skin care item are in people's lives in occupation of more
Carry out more consequence, people are higher and higher to the functional requirement of skin care item, are damaged to improve because of the stimulation such as ultraviolet light
Skin, it is tired or feel that the skin age increases bring children to improve skin to need a kind of topical composition with skin-care effect
Line or relaxation skin, inject vigour into and anger for skin.
Summary of the invention
The purpose of the present invention is to provide a kind of topical composition and preparation method thereof with skin-care effect.
The present invention provides a kind of topical compositions with skin-care effect, it is extracted with tetrahydro curcumin and Rhizoma Acori Calami
Object is active constituent, in addition the preparation that acceptable auxiliary material is prepared in cosmetics.
Further, the preparation is aqua, emulsion, frost, cream, film or gelling agent.
Further, acceptable auxiliary material in the cosmetics are as follows: thickener, moisturizer, solvent.
Further, it is mainly prepared by the raw material of following weight proportion:
0.35-0.65 parts of tetrahydro curcumin, 0.07~0.13 part of Rhizoma Acori Calami extract, 0.14-0.26 parts of thickener, moisturizing
10.99-20.41 parts of agent, 58.45~108.55 parts of solvent.
Further, it is prepared by the raw material of following weight proportion:
0.5 part of tetrahydro curcumin, 0.1 part of Rhizoma Acori Calami extract, 0.2 part of thickener, 15.7 parts of moisturizer, solvent 83.5
Part.
Further, the thickener is carbomer U21；The moisturizer is Sodium Hyaluronate 100-180 ten thousand, sweet
Oil, butanediol, pentanediol, glycine betaine, allantoin, niacinamide, acetyl chitosamine, methyl gluceth -20, arginine；Institute
Stating solvent is water.
Further, it is prepared by the raw material of following weight proportion:
0.5 part of tetrahydro curcumin, 0.1 part of Rhizoma Acori Calami extract, 0.2 part of carbomer U21, Sodium Hyaluronate 100-180 ten thousand
0.1 part, 3 parts of glycerol, 5 parts of butanediol, 3 parts of pentanediol, 2 parts of glycine betaine, 0.2 part of allantoin, 1 part of niacinamide, acetyl chitosamine
0.5 part, 0.8 part of methyl gluceth -20,0.1 part of arginine, 83.5 parts of water.
The present invention also provides a kind of methods for preparing aforementioned topical composition, it includes the following steps:
(1) A phase swelling solution: taking the water of formula ratio 20-40%, and thickener is put into water, stirring swelling.
(2) B phase dispersant liquid: taking macromolecular class moisturizer and polyalcohols moisturizer, be uniformly dispersed, spare；
(3) take the water of formula ratio 55-75%, successively put into B phase dispersant liquid, A phase swelling solution, remaining moisturizer, activity at
Point, moisturizing is stirred evenly to enough to obtain the final product.
The present invention finally provides a kind of aforementioned topical composition in the change for preparing anti-oxidant, whitening, moisturizing, anti-aging
Purposes in cosmetic.
Further, the cosmetics are Essence.
Tetrahydro curcumin has anti-oxidation function, energy delaying skin aging in topical composition of the present invention, and uses hiding
Calamus extract, Sodium Hyaluronate, allantoin are moisturizer and skin conditioning agent, improve skin, lock moisture of skin, increase skin
Skin elasticity.Therefore, topical composition of the present invention not only has preferable moisturizing, moisturizing effect, it may have stronger anti-aging ability,
Endlessly power can be provided for skin.
Topical composition of the present invention can be obviously improved the symptom of impaired skin, have good anti-oxidant, anti-aging effects,
It has no toxic side effect, there is stronger practical application value.It is steady well that stability study shows that topical composition of the present invention has
It is qualitative.
Above content according to the present invention, according to the ordinary technical knowledge and customary means of relevant art, not
It is detached under the premise of the above-mentioned basic fundamental thought of the present invention, the modification, replacement or change of other diversified forms can also be made.
The specific embodiment of form by the following examples remakes further specifically above content of the invention
It is bright.But the range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to example below.It is all to be based on above content of the present invention
The technology realized all belongs to the scope of the present invention.
Detailed description of the invention
Fig. 1 essence sensory evaluation radar map
Specific embodiment
Raw material, equipment used in the specific embodiment of the invention are known product, are obtained by purchase commercial product.
Rhizoma Acori Calami extract is to be applicable in the present invention using what any method was extracted by being commercially available.
Tetrahydro curcumin is to be commercially available, and is applicable in the present invention using what any method obtained.
The preparation of the Essence of the present invention of embodiment 1
1, the dosage of each raw material of Essence of the present invention is as shown in table 1.
The dosage of 1 embodiment of table, 1 each raw material of Essence
2, preparation method
(1) A phase swelling solution: taking the water of formula ratio 20-40%, and carbomer U21 is put into water, stirring swelling.
(2) B phase dispersant liquid: take suitable container by Sodium Hyaluronate (100-180 ten thousand), glycerol, butanediol, pentanediol point
It dissipates uniform；
(3) water of formula ratio 55-75% is taken, B phase dispersant liquid, A phase swelling solution, D phase materials (arginine), C are successively put into
Mutually each material (Nano Active THC, glycine betaine, allantoin, niacinamide, acetyl chitosamine, methyl gluceth -20, hiding
Calamus extract), and container containing is rinsed with aqua sterilisa, water supplement is stirred evenly to enough to obtain the final product.
3, application method
The Essence of the present embodiment is in use, be suitable for taking suitable Essence to be applied on the face after cleaning face skin, making
It is evenly dispersed, it gently pats and promotes to absorb.Pay attention to using every time excessively should not also use under skin allergic conditions.
Illustrate beneficial effects of the present invention below by way of the mode of test example:
The sensory evaluation of the Essence of the present invention of test example 1
1. sensory evaluation control laboratory selects
Control laboratory should select quiet, interference-free environment, and the comfortable temperature of indoor holding and ventilation avoid unrelated gas
Taste pollutes test atmosphere.
2. the screening of sensory evaluation person
Hanking 25-40 years old 30 people of resident in city is valuation officer.
3. sensory evaluation person prepares
(1) valuation officer 5h not use skin care item.
(2) valuation officer's rinse arm 1min, hand is from tap 3cm.
(3) valuation officer stays in that humidity is (50 ± 10) % and temperature is 30min in the environment of (22 ± 1) DEG C.
(4) each valuation officer takes sample, prepares assessment.
4. sensory evaluation step
(1) it with surveying in 75% ethyl alcohol arm of cleaning and finger, is marked on the person's of revaluing arm after 3min: using 2.5cm
The lid of diameter covers ink paste, draws circle.
(2) each arm one circle, the beginning label at wrist 5cm are spaced 2cm between circle and circle.
(3) begin to use Essence of the present invention after 2min, take the product of 20 μ L to be distributed in circle with pipettor, smearing of looping
Uniformly.Assessment marking is carried out after smearing 3 circles.
(4) 5min assesses glossiness, consolidation, provoking property, wire drawing sense, spreadability, wettability, moistens after starting smearing
The indexs such as (water moisture feeling), heavy feeling, absorbability are spent, and options is filled in the table.
(5) after assessing, all forms are collected.
5. evaluation index
6. data are analyzed
It is for statistical analysis using score value of the arithmetic mean method to indices, and draw radar map (see Fig. 1).
The consumer tests of the Essence of the present invention of test example 2
This questionnaire samples 100 people, tries out 80 people, and main result is as follows:
A, consumption market whitening is in great demand: more than half consumers have the colour of skin it is obscure, it is uneven, jaundice puzzlement；Four at disappearing above
Expense person is using the skin-protection product for having white-skinned face function at present.
B, the anti-oxidant demand in consumption market is just in the rapid growth phase: more than half consumers for it is anti-oxidant with it is anti-ageing have it is natural
Think；More than half consumers recognize in more expensive price quartile oxidation resistant price；Three be used at the above consumer it is anti-oxidant
Product expresses willingness more than half consumer and begins trying oxidation resistant product；Consumer is embodied oxidation resistant product effect
It is interpreted as delaying wrinkle generation, even skin tone, promotes skin elasticity.
C, consumer has certain cognition to whitening composition: consumer to the whitening composition of high fire for example Trenaxmine, arbutin,
The cognition degrees such as VC, niacinamide are higher (62%).
D, consumer's cognition only simple for antioxidant content: consumer without too high cognition, surpasses antioxidant content
Antioxidant content cannot directly be said by crossing eighty per cant consumer；For anti-oxidant single-item, it is small that Lancome was mentioned more than twenty percent consumer
Black bottle skin base solution；
E, turmeric is not known about, but high to plant component skin care item acceptance: nearly sixty percent consumer think plant component=
It is safe, mild；It is low (less than 5%) without prompt referral rate as whitening antioxidation ingredient turmeric/THC, due to after explanatory power
Through being accommodated by the mature plant extract of education, consumer's trial degree is higher (60% or more).
F, evaluation is tried out:
A) sense of product skin is good, not sticky, easily pushes open and easily absorbs (92%)
B) there is light plant flavour, it is naturally pure and fresh (95%)
C) at once whitening effect it is unobvious (consumer think can whitening at once skin care item may contain it is harmful to skin at
Point.70% or so consumer is ready to be limited to one month when the longest effect received, i.e., has macroscopic whitening in one month
Effect can receive)
D) using the effect for after 28 days, thering is 65% subject to identify oneself to there is the colour of skin to highlight
E) using after 28 days, there is 80% subject to identify oneself the effect for having skin consolidation, 65% thinks have desalination subtle
Effect
F) using after 28 days, 95% subject identifies oneself the effect for having moist moisturizing
G) using after 28 days, there is 95% or more subject's satisfaction
H) 90% or more subject thinks to be ready to recommend friend of the product to oneself, and rationale for the recommendation is uniformly to highlight skin
Color, consolidation skin
To sum up, topical composition of the present invention not only has preferable moisturizing, moisturizing effect, it may have stronger anti-oxidant, anti-
Aging ability can be obviously improved the symptom of impaired skin, have no toxic side effect, and have stronger practical application value.Stability is ground
Study carefully and shows that topical composition of the present invention has good stability, it is easy to use, with good application prospect.
Claims (10)
1. a kind of topical composition with skin-care effect, it is characterised in that: it is with tetrahydro curcumin and Rhizoma Acori Calami extract
For active constituent, in addition the preparation that acceptable auxiliary material is prepared in cosmetics.
2. topical composition according to claim 1, it is characterised in that: the preparation is aqua, emulsion, frost, cream, film
Agent or gelling agent.
3. topical composition according to claim 1, it is characterised in that: acceptable auxiliary material in the cosmetics are as follows: increase
Thick dose, moisturizer, solvent.
4. topical composition according to any one of claims 1 to 3, it is characterised in that: it is mainly by following weight
The raw material of proportion is prepared:
0.35~0.65 part of tetrahydro curcumin, 0.07~0.13 part of Rhizoma Acori Calami extract, 0.14-0.26 parts of thickener, moisturizer
10.99-20.41 parts, 58.45~108.55 parts of solvent.
5. topical composition according to claim 4, it is characterised in that: it be by following weight proportion raw material preparation and
At:
0.5 part of tetrahydro curcumin, 0.1 part of Rhizoma Acori Calami extract, 0.2 part of thickener, 15.7 parts of moisturizer, 83.5 parts of solvent.
6. according to topical composition described in claim 3~5 any one, it is characterised in that: the thickener is carbomer
U21；The moisturizer be Sodium Hyaluronate 100-180 ten thousand, glycerol, butanediol, pentanediol, glycine betaine, allantoin, niacinamide,
Acetyl chitosamine, methyl gluceth -20, arginine；The solvent is water.
7. topical composition described in any one according to claim 1~6, it is characterised in that: it is by following weight proportion
Raw material be prepared:
0.5 part of tetrahydro curcumin, 0.1 part of Rhizoma Acori Calami extract, 0.2 part of carbomer U21, Sodium Hyaluronate 100-180 10,000
Part, 3 parts of glycerol, 5 parts of butanediol, 3 parts of pentanediol, 2 parts of glycine betaine, 0.2 part of allantoin, 1 part of niacinamide, acetyl chitosamine 0.5
Part, 0.8 part of methyl gluceth -20,0.1 part of arginine, 83.5 parts of water.
8. a kind of method for preparing topical composition described in claim 1~7 any one, it is characterised in that: it includes as follows
Step:
(1) A phase swelling solution: taking the water of formula ratio 20-40%, and thickener is put into water, stirring swelling.
(2) B phase dispersant liquid: taking macromolecular class moisturizer and polyalcohols moisturizer, be uniformly dispersed, spare；
(3) water of formula ratio 55-75% is taken, B phase dispersant liquid, A phase swelling solution, remaining moisturizer, active constituent, benefit are successively put into
Water is stirred evenly to enough to obtain the final product.
9. topical composition described in claim 1~7 any one is in the change for preparing anti-oxidant, whitening, moisturizing, anti-aging
Purposes in cosmetic.
10. purposes according to claim 9, it is characterised in that: the cosmetics are Essence.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2019100547196 | 2019-01-21 | ||
| CN201910054719 | 2019-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110037974A true CN110037974A (en) | 2019-07-23 |
Family
ID=67283916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910452590.4A Pending CN110037974A (en) | 2019-01-21 | 2019-05-28 | A kind of topical composition and preparation method thereof with skin-care effect |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110037974A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101212952A (en) * | 2005-05-27 | 2008-07-02 | 株式会社林原生物化学研究所 | Agent for external application to the skin |
| KR20090044111A (en) * | 2007-10-31 | 2009-05-07 | 주식회사 코리아나화장품 | Cosmetic composition for skin-whitening comprising nymphaea caerulea and tetrahydrocurcumin |
| WO2015164504A1 (en) * | 2014-04-23 | 2015-10-29 | Lifevantage Corporation | Topical compositions and methods for reducing oxidative stress |
| WO2016061284A1 (en) * | 2014-10-14 | 2016-04-21 | Biocogent, Llc | Compositions and methods comprising extracts of zingiberaceae |
| CN107320374A (en) * | 2017-07-12 | 2017-11-07 | 拉芳家化股份有限公司 | A kind of skin care milk containing curcumin analogue |
| CN108498390A (en) * | 2017-02-24 | 2018-09-07 | 西藏奇正藏药股份有限公司 | A kind of Tibetan book on Chinese herbal medicine extract and the preparation method and application thereof for treating acne |
-
2019
- 2019-05-28 CN CN201910452590.4A patent/CN110037974A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101212952A (en) * | 2005-05-27 | 2008-07-02 | 株式会社林原生物化学研究所 | Agent for external application to the skin |
| KR20090044111A (en) * | 2007-10-31 | 2009-05-07 | 주식회사 코리아나화장품 | Cosmetic composition for skin-whitening comprising nymphaea caerulea and tetrahydrocurcumin |
| WO2015164504A1 (en) * | 2014-04-23 | 2015-10-29 | Lifevantage Corporation | Topical compositions and methods for reducing oxidative stress |
| WO2016061284A1 (en) * | 2014-10-14 | 2016-04-21 | Biocogent, Llc | Compositions and methods comprising extracts of zingiberaceae |
| CN108498390A (en) * | 2017-02-24 | 2018-09-07 | 西藏奇正藏药股份有限公司 | A kind of Tibetan book on Chinese herbal medicine extract and the preparation method and application thereof for treating acne |
| CN107320374A (en) * | 2017-07-12 | 2017-11-07 | 拉芳家化股份有限公司 | A kind of skin care milk containing curcumin analogue |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108714110B (en) | A kind of whitening spot-removing compound | |
| CN110200881A (en) | A kind of cosmetics and preparation method thereof containing tetrahydro curcumin | |
| CN110200875A (en) | A kind of antiallergic whitening mask and preparation method thereof | |
| CN102641233B (en) | Rhodiola crenulata facial mask with whitening and moisturizing effects | |
| CN103585096B (en) | A kind of face of living essence and preparation method thereof that compacts | |
| CN105534796B (en) | A kind of antiallergy toner containing Folium Artemisiae Argyi extract and preparation method thereof | |
| CN103610633B (en) | Cosmetic combination containing Herba Herminii Pleurotus ferulae Lanzi fermentation liquid | |
| CN107961211A (en) | Cosmetic composition | |
| CN109106677B (en) | Composition with whitening function and application thereof | |
| CN106333894A (en) | Method for preparing natural sunscreen and skin whitening components in cosmetics by utilizing fruits | |
| CN110037981A (en) | A kind of skin care item and the preparation method and application thereof | |
| CN107375095A (en) | A kind of whitening, moisturizing essence and preparation method thereof | |
| CN110151642A (en) | A kind of Whitening, spot exfoliating skin care item and its preparation process | |
| CN110742843B (en) | Anti-aging traditional Chinese medicine extract of ginseng and glossy ganoderma as well as preparation method and application thereof | |
| CN108714126A (en) | Skin care compositions and the preparation method and application thereof with moisturizing and anti-oxidation efficacy | |
| KR101233832B1 (en) | A COSMETIC COMPOSITION CONTAINING GINSENOSIDE Re AND Rh2 COMPLEX FROM RED GINSENG AND THE MANUFACTURING METHOD | |
| CN114805485A (en) | Chlorella bioactive peptide and application thereof in preparation of anti-aging essence | |
| CN110292543A (en) | It is a kind of substitute ultraviolet absorbing agent biological composition and its application | |
| CN107362094A (en) | Plant beauty stoste and preparation method thereof | |
| Patil et al. | A review on: standerdization of herb in new era of cosmaceuticals: herbal cosmetics | |
| CN114306161A (en) | Anti-aging composition and preparation method and application thereof | |
| CN104546621B (en) | A kind of skin care anti-apolexis composition and preparation method thereof | |
| CN109998939A (en) | Crease-resistant Firm composition, crease-resistant Firm Essence and preparation method thereof | |
| CN109464308A (en) | A kind of essential oil composition and application with anti-blue light skin-care effect | |
| CN107789252A (en) | A kind of Skin whitening care cosmeticses |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |