CN110025494A - A kind of collagen containing coypu and the shin moisturizer of seaweed zymolyte and preparation method thereof - Google Patents
A kind of collagen containing coypu and the shin moisturizer of seaweed zymolyte and preparation method thereof Download PDFInfo
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- CN110025494A CN110025494A CN201910401903.3A CN201910401903A CN110025494A CN 110025494 A CN110025494 A CN 110025494A CN 201910401903 A CN201910401903 A CN 201910401903A CN 110025494 A CN110025494 A CN 110025494A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9722—Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The invention discloses a kind of collagens containing coypu and the shin moisturizer of seaweed zymolyte and preparation method thereof, including following components: coypu collagen, seaweed zymolyte, Sweet Almond Oil, Lavender, refined jasmine oil, saualane, 1,3-BDO, polyethylene glycol, polysorbas20, panthenol, xanthan gum, tocopherol, allantoin, hyaluronic acid, EDTA-2Na, deionized water；Preparation method includes: (1) preparation coypu collagen, and (2) prepare seaweed zymolyte, and (3) prepare oil phase thing, and (4) prepare aqueous-phase material, and (5) prepare finished product.The collective effect of coypu collagen and seaweed zymolyte isoreactivity substance in finished product of the invention, it can achieve moisturizing water lock, promote skin vigor, tenderization skin, bright color, adjust acid-base scale of skin, maintain skin oil-water balance, increase the multiple efficacies such as skin elasticity, the crowd suitable for different sexes, age and skin quality.
Description
Technical field
The present invention relates to technical field of skin care, the skin care of specifically a kind of collagen containing coypu and seaweed zymolyte
Liquid and preparation method thereof.
Background technique
With development, the progress of medicine and the improvement of quality of life of society, people start to focus on the maintenance of skin.Due to
The air pollution and increasingly increased life stress that modern society gradually aggravates, the skin of more and more people is by external environment
, there are a series of symptoms such as obscure, dry, sensitive, aging in the invasion of pollution and internal free radical.As people are to skin care
The attention degree of problem increases, and skin care is essential important link in the program of daily skin care.
Skin has the function of that defence is dry, keeps moisture, and moisture is and important, skin for cell and biology
Also there is defence ultraviolet light, adjust body temperature, neutralize the multiple functions such as environmental stimuli, but with the variation of environment and age ageing
It influences that the imbalance in function and structure can also occur, fibroblastic synthesis capability decline, if lacking collagen in skin
Albumen, collagenous fibres will occur connection solidification, reduce iuntercellular mucopolysaccharide, and skin will lose soft, elasticity and gloss, hair
Raw aging, while the fibrous fracture of corium, lipoatrophia, sweat gland and smegma are reduced, and skin is made color spot, wrinkle etc. occur
A series of aging phenomena.Using skin-protection product can the appropriate function and structure that must adjust skin, many shields on the market at present
Skin liquid often adds excessive chemicals and preservative etc., although can achieve the purpose that the short time improves skin,
Skin can be made to generate dependence or have intense stimulus to skin.Therefore, natural, health, non-stimulated shin moisturizer increasingly by
Consumer's likes.
Collagen is a kind of structural protein for being present in cytoplasm, it is distributed widely in animal skin tissue,
With no cytotoxicity, regulatable biodegradation rate, interaction, the physiology item that specifically can promote or inhibit cell material
Many advantages, such as biochemistry compatibility of part is excellent.The source of collagen is generally pig, ox, fish etc., pig currently on the market
Zoonosis is obtained with Niu Rongyi, the source as collagen is there are unsafe factor, and pig and Niu Zuowei large size livestock,
With raising, the disadvantages of period is long, benefit is low, disease is more, easy drug abuse, and the most wide fish source of application range now, it is practical
On due to higher cost using deep-sea fish extract it is seldom, mostly or extracted with common fish.There are ring in many coastal areas
Border is polluted, and often there is heavy metals exceeding standard phenomenon in Fish, and there are security risks.In addition, pig, ox, fish are as collagen
Source, need to lose hair or feathers by strong acid, highly basic mostly, thaw, pre-processing and etc., harmful chemical agents will cause environmental pollution.
Therefore, furskin of nutria becomes a kind of novel collagen extraction raw material.
Open source literature also reports some technologies that skin care field is used for about coypu or algae extract, example
Such as:
1, Chinese patent: a kind of castor rat-tail muscle extracts the facial mask liquid and preparation method thereof of collagen peptide；Application number:
201810520392.2；Applicant: the Heilungkiang biotech inc Li Haixin；Abstract: the present invention relates to a kind of seas
Leopard cat rat-tail muscle extracts the facial mask liquid and preparation method thereof of collagen peptide, and the facial mask liquid is prepared from the following raw materials: water, glycerol,
1,3 butylene glycol, beta glucan, castor rat-tail muscle extract collagen peptide, vitamin E, Crodaret, digestion
Oligomerization Sodium Hyaluronate, low-numerator sodium hyaluronate, Sodium Hyaluronate, Scleroglucan, triethanolamine, xanthan gum, EDTA-2Na；
Collagen peptide facial mask liquid of the invention is free of preservative, essence, fluorescer etc. to human body harmful substance, than currently on the market
The facial mask used has more permeability, trophism, prosthetic, moisture retention, compatibility and whitening wrinkle removing effect, the infiltration of energy deep layer
Skin persistently supplements skin nutrition and moisture, and forms layer protecting film in skin surface, and the moisture for protecting skin to supplement does not flow
It loses, repairs aging and damaged cell, reach permanent beauty treatment effect.
2, Chinese patent: a kind of zymolyte containing seaweed and the multi-functional lotion of collagen and preparation method thereof；Application number:
201610128836.9；Applicant: Chinese Marine University；Abstract: the invention discloses a kind of zymolyte containing seaweed and collagen eggs
White multi-functional lotion comprising: 1,3-BDO, glycerine, polysorbate -20, panthenol, hexadecanol, octadecyl alcolol, fertility
Phenol, allantoin, hyaluronic acid, disodium ethylene diamine tetraacetate, Sweet Almond Oil, saualane, octyldodecanol, lemon, sea
Algae zymolyte, fish scale collagen, triethanolamine；The invention also discloses the preparation methods of above-mentioned multi-functional lotion.The present invention
Multi-functional lotion using the zymolyte of tangleweed and fish scale collagen as main active, cooperation addition hyaluronic acid,
Tocopherol, saualane and allantoin isoreactivity ingredient, mix, homogeneous is formed with cosmetic base, have safety, mild, whitening,
Moisturizing, wrinkle resistant, anti-aging, non-stimulated advantage, not but not damage skin, moreover it is possible to had both while protecting moisturizing whitening,
Crease-resistant, anti-aging effect.
In the prior art there are no the technical solution that coypu collagen is prepared to shin moisturizer in conjunction with marine algae extract,
Therefore, cosmetic technical field need to provide a kind of safety, it is mild, efficiently and have moisturizing, whitening, crease-resistant, anti-aging etc. more
The shin moisturizer of kind effect has good development prospect.
Coypu (scientific name:Myocastor coypus) also known as nutria, figure is big, and short and thick, body is 43~65 centimetres long, body
5~10 kilograms are weighed, Xi He, Chi Hu and water channel etc. are inhabited, is lived in caves.Phytophagous also eats mollusk, and whole year can breed,
Young rat development can breed by 3 months, and period of pregnancy is 132 days.Second day of postpartum can be matched, and can produce two tires within 1 year, often
Tire produces 6~14, can produce 5 tires within period of high birth 2 years.Coypu growth is fast, and it is important fur-bearing animal that reproductive capacity is strong, and meat is edible, now
Worldwide extensive raising.Castor rat meat is also known as sea otter meat, high protein, low fat, content of hemoglobin pole in the international market
Height, free from extraneous odour.It is identified through national meat instrument quality Supervision Test Center and Beijing nutrient source research institute, crude protein content reaches
25%, contain 18 kinds of amino acid, 30 various trace elements, especially zinc and calcium are higher by several times than general livestock meat, are Ms's beauty
Hold the ultimate food developed, increased intelligence with children's torso.Coypu has good anti-due to delicious meat, full of nutrition
Decline health-care effect, has been recognized and has received, and becomes the delicious food on dining table.And slaughter coypu will generate sea naturally
Leopard cat mouse skin also becomes the hot spot of people's research to the comprehensive utilization of furskin of nutria.Furskin of nutria hair quality it is thick and solid, soft resistance to
Mill, appearance is magnificent, villus is close, draining and good heat preservation performance, can be prepared into clothes.It domestic market will to the demand of coypu
Increasing, carrying out comprehensive utilization to coypu and its by-product has very wide prospect.
Summary of the invention
The object of the present invention is to provide the shin moisturizer and its preparation side of a kind of collagen containing coypu and seaweed zymolyte
Method, the shin moisturizer can achieve moisturizing water lock, promote skin vigor, tenderization skin, bright color, adjust acid-base scale of skin, dimension
It holds skin oil-water balance, increase the multiple efficacies such as skin elasticity, and be suitable for different sexes, the crowd at age and skin quality.
The invention is realized by the following technical scheme:
A kind of shin moisturizer of collagen containing coypu and seaweed zymolyte, including following components: coypu collagen, seaweed
Zymolyte, Sweet Almond Oil, Lavender, refined jasmine oil, saualane, 1,3 butylene glycol, polyethylene glycol, polysorbas20, panthenol, Huang
Virgin rubber, tocopherol, allantoin, hyaluronic acid, EDTA-2Na, deionized water.
Above-mentioned each component is by weight percentage are as follows: coypu collagen 0.1~10%, seaweed zymolyte 0.1~10%,
Sweet Almond Oil 0.05~2%, Lavender 0.05~2%, refined jasmine oil 0.05~2%, saualane 1~10%, 1,3-BDO 1
~10%, polyethylene glycol 1~8%, polysorbas20 1~5%, panthenol 0.5~5%, xanthan gum 0.5~5%, tocopherol 0.1~4%, allantois
Element 0.05~4%, hyaluronic acid 0.05~5%, EDTA-2Na 0.05~2%, surplus is deionized water.
The shin moisturizer of the collagen containing coypu and seaweed zymolyte, preparation method includes the following steps:
(1) prepare coypu collagen: taking and cleaned with clear water after fresh furskin of nutria unhairing, removal of impurities, according to solid-liquid ratio 1:8~
10 are added the EDTA solution of 0.2mo1/L, impregnate 6~7h and remove non-collagen；It takes out furskin of nutria and 2000U/g is added
5~10% citric acid solution is added according to solid-liquid ratio 1:16~20 for pepsin, impregnates 24~48h and extracts；It filters
To collagen extracting solution, it is 0.9mol/L that sodium chloride to its concentration is added into extracting solution, and saltout 20~28h, and centrifugation obtains
Collagen deposit object puts the precipitate in the bag filter that trapped molecular weight is 10kD the 20~28h that dialyses, is lyophilized spare；
(2) it preparing seaweed zymolyte: seaweed being cleaned, drying, crush the algae powder for 50~100 mesh, every 1g algae powder is added 500~
The enzyme and 100mL water of l000U/g is uniformly mixed, maintains the temperature at 30~60 DEG C, extract 12~24 hours under oscillating condition, from
10~20min of the heart rotates after suction filtration, seaweed zymolyte is obtained after freeze-drying；
(3) it prepares oil phase thing: Sweet Almond Oil, saualane being added by weight percentage, is heated to 70~75 under stirring condition
DEG C, so that it is fused into liquid, obtains oil phase thing；
(4) prepare aqueous-phase material: in another container by weight percentage by 1,3 butylene glycol, polyethylene glycol, polysorbas20, panthenol,
Xanthan gum, tocopherol, allantoin, hyaluronic acid, EDTA-2Na are uniformly mixed, and deionized water is added, is heated under stirring condition
It 70~75 DEG C, is allowed to be completely dissolved, obtains aqueous-phase material；
(5) it prepares finished product: oil phase thing is added in aqueous-phase material, Lavender, jasmine essence are added after being cooled to 40~50 DEG C
Oil, seaweed zymolyte and coypu collagen, with blender high-speed stirred；Adjusting pH to 5.0~6.0, homogeneous 10~
30min is cooled to room temperature；Extracting solution is placed in and is aged 1~3 day at room temperature, finished product shin moisturizer is obtained after filling.
Seaweed described in step (2) includes the combination of one or more of brown alga, red algae, green alga；
Brown alga (Phaeophyta) it is the higher algae of a group, it is metaphyte, about 1500 kinds, is distributed the cold of continent bank
Water water body, it is rare in fresh water.Brown alga generally contain a large amount of yellowish orange phycophaein (fucoxanthin), therefore it is how brown, furthermore
Chlorophyll a, Chlorofucsin, carrotene and lutein also rich in etc..Its photosynthate is essential oil, laminaran
(Laminarin) and mannitol (mannitol), cell wall is rich in phycocolloid substance, has gluey or thick characteristic, often quilt
For various food, utilization pharmaceutically more has history of more than one thousand years.Common brown alga have Ectocarpus (Ectocarpus), brown alga
Larminaria (Laminaria), Killeen (Pelvetia), thallus laminariae (Ecklonia hornem), thallus laminariae (Undaria pinnatifida), sargassum fusifome (Sargassum fusiforme) etc..
Red algae (Rhodophyta) it is most be multicell, only a few is the algae of slender cell space.Frond is purplish red,
The colors such as rose-red, dark red, the red algae overwhelming majority are grown in Yu Haiyang, and distribution is wide, and type is more, and there are about 558 categories, more than 3740 according to statistics
Kind, and it is divided into two subclasses: seaweed subclass (Bangioideae) and Florideae (Florideae).Red algae includes algae red
Element, algocyan, chlorophyll a, chlorophyll b, carrotene and lutein etc., reserve nutrient for floridean starch (floridean starch) or floridose (floridose).Common red algae has batrachospermum (Batrachospermum), extra large rope face to belong to
(Nemalion), coral Trentepohlia (Corallina), Ceramium (Ceramium), Rhodomela (Rhodomela) and Gelidium
(Gelidium) etc..
Green alga (Chlorophyta) green alga is more common in fresh water, it is often attached to the rock and wood of heavy water, or swim in stagnant water
Surface；Also there is the type moved in soil or seawater.The cell of desmid is similar to higher plant, also there is nucleus and leaf
Green body has similar pigment, reserves nutrient and the ingredient of cell wall, most with chlorophyll a and b in pigment, there are also lutein and
Carrotene, therefore in green.The nutriment of storage is mainly starch and oils.Common green alga has Chlamydomonas
(Chlamydomonas), desmids, Hydrodictyton (Hydrodictyon), volvox (Volvox), Spirogyra
(Spirogyra), Acetabularia (Actebaularia), caulerpa category (Caulerpa) etc..
Enzyme described in step (2) be alkali protease, cellulase, pentosan complex enzyme, cellulose complex enzyme one
Kind or several combinations.
Application of the shin moisturizer in terms of preparing facial mask is prepared into facial mask, facial mask using shin moisturizer as facial mask stoste
Form can be for film, patch, cream, gel etc..
The shin moisturizer is preparing application of the skin care item perhaps in terms of cosmetics using shin moisturizer as raw material or auxiliary material
It is prepared into corresponding product.The skin care item include essence lotion, toner, essence cream, lotion, face cream, stoste, essence
Dew, spraying, body lotion etc., the cosmetics include cleansing cream, facial cleanser, toner, make up remover, concealer, vanishing cream, essence
Magnificent frost etc. is mainly used for the cosmetics of face.
Chemical composition, the structure of collagen impart it be beauty basis.Collagen is generally extracted by Animal Skin,
Also containing proteoglycans such as hyaluronic acid, chondroitin sulfates in addition to collagen in skin, they contain a large amount of polar groups, are to protect
The wet factor, and play the role of that the tyrosine in skin is prevented to be converted into melanin, thus collagen have pure natural moisturizing, whitening,
It the effects of wrinkle resistant, nti-freckle, can be widely applied in cosmetic products.Collagen is similar to the structure of human skin collagen, is non-
Soluble fibrous contains glycoprotein, is rich in a large amount of amino acid and hydrophilic group in molecule, with certain surface-active and very well
Compatibility, simultaneously because containing a large amount of hydroxyl in its molecule, therefore it has fairly good moisture-keeping function.In relative humidity
When 70%, the moisture of its own weight 45% can be still kept.Test proves: the pure solution of 0.01% collagen can be formed very well
Water conservation layer, supply skin required for whole moisture.The coypu collagen that the present invention extracts is even more to have its unique
The effect of skin care, beauty, in furskin of nutria extraction of substance, collagen isoreactivity ingredient can be spread to the deep layer of skin,
Tyrosine competition in the tyrosine and skin contained, and in conjunction with the catalytic center of tyrosinase, to inhibit melanin
It generates, makes the collagen increased activity in skin, keep the integrality of cuticula moisture and fibre structure, promote skin group
The metabolism knitted generates good moist moisturizing to skin, effect wrinkles eliminating vanishing acts on.
Following functions statement is carried out for the partial supplementary material that the present invention uses:
Sweet Almond Oil is a kind of base oil of neutrality, is squeezed by apricot fruit and is obtained, main component be vitamin A, B1, B2,
B6, E, protein, fatty acid etc..Pale yellow, smell faint scent.Rich in polybasic unsaturated fatty acid, vitamin D, E and protein
Equal substances can soft skin, moisturizing, specially control skin itch, be red and swollen, dry and pimples.Quality is relaxed and comfortable soft, moist and non-greasy.
2, extremely mild, there is good skin-friendly, even most delicate baby can use.Neutrality is releived, salubrious oiliness, quality
Quite soft, lubrication, is least greasy base oil, can all reconcile mutually with any vegetable oil, also with isolation ultraviolet
Effect, therefore be also most widely used base oil.
Lavender (Lavender Oil): it is refined by lavender, can be clearing heat and detoxicating, cleaning skin, control
Oil, freckle removing and whitening, the tender skin of anti-wrinkle, eye haustra -dsipelling black eye also have and promote the skin-protecting functions such as regeneration of damaged tissue recovery.It smokes
Clothing grass essential oil also has sedation effect to heart, can reduce hypertension, pacify palpitaition, helpful for having a sleepless night.Lavender
Complement each other with refined jasmine oil, can rapid osmotic hair follicle disinfecting, antimicrobial, promote cytothesis, restore skin connective tissue, simultaneously
Balance skin surface layer fat secretion, sensitive skin of releiving, convergence pore, supplement skin moisture, persistently protect skin not by the youth
The interference of acne acne, restores the moist skin of zero pore, zero small pox.
Refined jasmine oil (Jasmine essential oil): it is referred to as " king of essential oil ", it is nontoxic, non-stimulated, there is elegance
The fragrance of fragrance, the gloomy mood that can releive inspires enthusiasm, promotes self-confidence, at the same can nurse and improve dry skin, water shortage,
Oil and sensitive situation are crossed, striae of pregnancy and scar are desalinated, increases skin elasticity, skin is allowed to feel more tender.
Saualane (Squalane): the squalene extracted in hydrogenated hydro carbons grease is hydrogenated to be made a kind of squalene extracting, therefore
Also known as eepwater shark liver oil.Scientific research discovery, saualane are that rare chemical stability is high, the splendid animal oil of use feeling
Rouge has preferable compatibility to skin, has lower polarity and medium spreadability, may also suppress the growth of mould.Spiny dogfish
Alkane is a kind of lipid closest to human sebaceous, and affinity is strong, can combine together with the sebum film of mankind itself, in skin table
Face forms one layer of natural barrier, reinforces maintenance skin epidermis；Can also skin pore be made to open, promote blood microcirculation, promoted
Damaged cell is repaired in the metabolism of cell, help.Saualane can also inhibit the peroxidating of skin lipid, can effectively infiltrate through flesh
Skin, and promote the proliferation of skin base cell, to delay skin aging, improving and eliminating chloasma has apparent physiology to imitate
Fruit.
Tocopherol (Tocopherol): tocopherol is the hydrolysate of vitamin E, is that the natural oil of current mass production is molten
Property antioxidant.Tocopherol can increase the antioxidation of cell, maintain and promote Reproductive Performance, have centainly anti-aging
Effect, moreover it is possible to improve lipid-metabolism, prevent artery sclerosis, reduce blood lipid.
Allantoin (Allantoin) it is a kind of amphoteric compound, double salt can be formed in conjunction with many kinds of substance, have and be protected from light, kill
Bacterium anti-corrosion, analgesic, antioxidation can make skin keep moisture content, moisten and soft.Allantoin, which has, promotes cell growth, adds
Fast wound healing, the physiological functions such as cutin-softening albumen are the good consolidant and antiulcer agents of skin trauma.It can be used as delaying
Solution and treatment xerodermia, scaling skin illness, skin ulcer, digestive tract ulcer and inflammation, to osteomyelitis, diabetes, liver
Hardening, acne have good therapeutic effect.
Hyaluronic acid (Hyaluronic acid): also known as uronic acid, D-Glucose aldehydic acid and N-acetyl-glucosamine composition
Dissacharide units sodium hyaluronate is a kind of acid mucopolysaccharide.Hyaluronic acid is with its unique molecular structure and physicochemical property in body
Show a variety of important physiological functions, such as lubricating joint adjusts the permeability of vascular wall, regulatory protein matter, and Water-Electrolyte expands
It dissipates and operates, promote wound healing etc..Particular, it is important that hyaluronic acid has special water retention, it is presently found
The best substance of moisture retention in nature, referred to as ideal natural moisturizing factor (NMF).Hyaluronic acid can also promote epidermis thin
The proliferation of born of the same parents and differentiation, scavenging activated oxygen, can prevent and repair skin injury.The aqueous solution of hyaluronic acid has very high viscous
Degree, can be such that water phase thickens；Lotion uniform and smooth with after oily mutually emulsification, has stable emulsion effect.
Beneficial effects of the present invention:
1, shin moisturizer of the invention has shield well by addition coypu collagen and seaweed zymolyte isoreactivity substance
Skin, beauty effect, will not will not generate dependence to skin irritant, it is safety, mild, efficiently, moreover it is possible to be protected in protection
Reach the multiple efficacies such as whitening, crease-resistant, anti-aging while wet.Suitable for the crowd of different sexes, age and skin quality, cost performance
Height, environmentally protective, preparation is simple, lower production costs, can carry out industrialized production.
2, it is primary raw material that the present invention, which selects pure natural tangleweed and coypu, extracts sea using Extraction Processes
Various bioactivators in algae, and collagen is extracted from furskin of nutria, fishy smell is few, extraction cost is low, these are natural
Active material can be absorbed by the skin rapidly, will not be born to skin tape, and natural antibacterial agent, antibacterial are contained in seaweed zymolyte
It works well.
3, the coypu collagen that the present invention extracts is even more to have the effect of its unique skin care, beauty, furskin of nutria
In extraction of substance, collagen isoreactivity ingredient can be spread to the deep layer of skin, the junket in tyrosine and skin contained
Propylhomoserin competition, and in conjunction with the catalytic center of tyrosinase, to inhibit the generation of melanin, keep the collagen in skin living
Property enhancing, keep the integrality of cuticula moisture and fibre structure, promote the metabolism of skin histology, skin is generated good
Moist moisturizing well, effect wrinkles eliminating vanishing effect.
4, the present invention extracts coypu collagen using furskin of nutria as raw material, not only for the comprehensive of furskin of nutria
Exploitation is closed, while also having widened the raw material of collagen extraction.Coypu collagen and seaweed zymolyte isoreactivity object
The collective effect of matter, can achieve moisturizing water lock, promoted skin vigor, tenderization skin, bright color, adjust acid-base scale of skin,
It maintains skin oil-water balance, increase the multiple efficacies such as skin elasticity, make one to show clear moving skin.
Specific embodiment
In order to keep technical solution of the present invention and advantage clearer, below with reference to the embodiment of the present invention, to the present invention
Technical solution be clearly and completely described.
Embodiment 1
A kind of shin moisturizer of collagen containing coypu and seaweed zymolyte, including following components by weight percentage: sea
Leopard cat mouse collagen 0.1%, seaweed zymolyte 3%, Sweet Almond Oil 0.05%, Lavender 0.05%, refined jasmine oil 0.1%, spiny dogfish
Alkane 8%, 1,3-BDO 5%, polyethylene glycol 5%, polysorbas20 1%, panthenol 3%, xanthan gum 0.5%, tocopherol 2%, allantoin 1%, thoroughly
Bright matter acid 0.1%, EDTA-2Na 0.05%, surplus are deionized water.
The shin moisturizer of the collagen containing coypu and seaweed zymolyte, preparation method includes the following steps:
(1) it prepares coypu collagen: being cleaned after taking fresh furskin of nutria unhairing, removal of impurities with clear water, added according to solid-liquid ratio 1:8
Enter to be added the EDTA solution of 0.2mo1/L, impregnates 7h and remove non-collagen；It takes out furskin of nutria and 2000U/g stomach cardia is added
Enzyme, 10% citric acid solution is added according to solid-liquid ratio 1:16, and immersion is extracted for 24 hours；Collagen extracting solution is obtained by filtration,
It is 0.9mol/L that sodium chloride to its concentration is added into extracting solution, is saltoutd for 24 hours, and centrifugation obtains collagen deposit object, will be precipitated
Object, which is placed in the bag filter that trapped molecular weight is 10kD, dialyses for 24 hours, is lyophilized spare；
(2) it prepares seaweed zymolyte: seaweed being cleaned, drying, crush the algae powder for 100 mesh, every 1g algae powder is added 700U/g's
Enzyme and 100mL water are uniformly mixed, maintain the temperature at 60 DEG C, extract 12 hours under oscillating condition, are centrifuged 10min, filter back spin
It steams, seaweed zymolyte is obtained after freeze-drying；
The seaweed is one of brown alga；The enzyme is alkali protease and cellulase；
(3) it prepares oil phase thing: Sweet Almond Oil, saualane being added by weight percentage, is heated to 72 DEG C under stirring condition, makes
It is fused into liquid, obtains oil phase thing；
(4) prepare aqueous-phase material: in another container by weight percentage by 1,3 butylene glycol, polyethylene glycol, polysorbas20, panthenol,
Xanthan gum, tocopherol, allantoin, hyaluronic acid, EDTA-2Na are uniformly mixed, and deionized water is added, is heated under stirring condition
It 72 DEG C, is allowed to be completely dissolved, obtains aqueous-phase material；
(5) it prepares finished product: oil phase thing is added in aqueous-phase material, Lavender, refined jasmine oil, sea are added after being cooled to 40 DEG C
Algae zymolyte and coypu collagen, with blender high-speed stirred；PH to 5.0 is adjusted, homogeneous 30min is cooled to room temperature；It will
Extracting solution is placed in be aged 3 days at room temperature, and finished product shin moisturizer is obtained after filling.
Embodiment 2
A kind of shin moisturizer of collagen containing coypu and seaweed zymolyte, including following components by weight percentage: sea
Leopard cat mouse collagen 0.5%, seaweed zymolyte 2%, Sweet Almond Oil 2%, Lavender 0.1%, refined jasmine oil 0.05%, saualane
10%, 1,3-BDO 5%, polyethylene glycol 1%, polysorbas20 1%, panthenol 5%, xanthan gum 1%, tocopherol 1%, allantoin 0.05%, thoroughly
Bright matter acid 0.1%, EDTA-2Na 0.1%, surplus are deionized water.
The shin moisturizer of the collagen containing coypu and seaweed zymolyte, preparation method includes the following steps:
(1) it prepares coypu collagen: being cleaned after taking fresh furskin of nutria unhairing, removal of impurities with clear water, according to solid-liquid ratio 1:10
The EDTA solution of 0.2mo1/L is added, impregnates 7h and removes non-collagen；It takes out furskin of nutria and 2000U/g stomach cardia is added
5% citric acid solution is added according to solid-liquid ratio 1:20 for enzyme, impregnates 30h and extracts；Collagen extracting solution is obtained by filtration,
It is 0.9mol/L that sodium chloride to its concentration is added into extracting solution, is saltoutd for 24 hours, and centrifugation obtains collagen deposit object, will be precipitated
Object, which is placed in the bag filter that trapped molecular weight is 10kD, dialyses for 24 hours, is lyophilized spare；
(2) it prepares seaweed zymolyte: seaweed being cleaned, drying, crush the algae powder for 100 mesh, every 1g algae powder is added 500U/g's
Enzyme and 100mL water are uniformly mixed, maintain the temperature at 50 DEG C, extract 18 hours under oscillating condition, are centrifuged 15min, filter back spin
It steams, seaweed zymolyte is obtained after freeze-drying；
The seaweed is one of red algae；The enzyme is the group of alkali protease, cellulase and pentosan complex enzyme
It closes；
(3) it prepares oil phase thing: Sweet Almond Oil, saualane being added by weight percentage, is heated to 75 DEG C under stirring condition, makes
It is fused into liquid, obtains oil phase thing；
(4) prepare aqueous-phase material: in another container by weight percentage by 1,3 butylene glycol, polyethylene glycol, polysorbas20, panthenol,
Xanthan gum, tocopherol, allantoin, hyaluronic acid, EDTA-2Na are uniformly mixed, and deionized water is added, is heated under stirring condition
It 75 DEG C, is allowed to be completely dissolved, obtains aqueous-phase material；
(5) it prepares finished product: oil phase thing is added in aqueous-phase material, Lavender, refined jasmine oil, sea are added after being cooled to 45 DEG C
Algae zymolyte and coypu collagen, with blender high-speed stirred；PH to 5.50 is adjusted, homogeneous 20min is cooled to room temperature；
Extracting solution is placed in and is aged 2 days at room temperature, finished product shin moisturizer is obtained after filling.
Embodiment 3
A kind of shin moisturizer of collagen containing coypu and seaweed zymolyte, including following components by weight percentage: sea
Leopard cat mouse collagen 1%, seaweed zymolyte 1%, Sweet Almond Oil 0.2%, Lavender 0.08%, refined jasmine oil 0.05%, saualane
4%, 1,3-BDO 10%, polyethylene glycol 4%, polysorbas20 2%, panthenol 1%, xanthan gum 0.5%, tocopherol 0.8%, allantoin 1%,
Hyaluronic acid 0.1%, EDTA-2Na 0.1%, surplus are deionized water.
The shin moisturizer of the collagen containing coypu and seaweed zymolyte, preparation method includes the following steps:
(1) it prepares coypu collagen: being cleaned after taking fresh furskin of nutria unhairing, removal of impurities with clear water, according to solid-liquid ratio 1:9
The EDTA solution of 0.2mo1/L is added, impregnates 7h and removes non-collagen；It takes out furskin of nutria and 2000U/g stomach cardia is added
Enzyme, 8% citric acid solution is added according to solid-liquid ratio 1:18, and immersion is extracted for 24 hours；Collagen extracting solution is obtained by filtration, to
It is 0.9mol/L that sodium chloride to its concentration is added in extracting solution, is saltoutd for 24 hours, and centrifugation obtains collagen deposit object, by sediment
It is placed in the bag filter that trapped molecular weight is 10kD and dialyses for 24 hours, be lyophilized spare；
(2) it prepares seaweed zymolyte: seaweed being cleaned, drying, crush the algae powder for 50 mesh, every 1g algae powder is added 1000U/g's
Enzyme and 100mL water are uniformly mixed, maintain the temperature at 35 DEG C, extract 24 hours under oscillating condition, are centrifuged 20min, filter back spin
It steams, seaweed zymolyte is obtained after freeze-drying；
The seaweed includes one of green alga；The enzyme is the combination of alkali protease and cellulose complex enzyme；
(3) it prepares oil phase thing: Sweet Almond Oil, saualane being added by weight percentage, is heated to 70 DEG C under stirring condition, makes
It is fused into liquid, obtains oil phase thing；
(4) prepare aqueous-phase material: in another container by weight percentage by 1,3 butylene glycol, polyethylene glycol, polysorbas20, panthenol,
Xanthan gum, tocopherol, allantoin, hyaluronic acid, EDTA-2Na are uniformly mixed, and deionized water is added, is heated under stirring condition
It 70 DEG C, is allowed to be completely dissolved, obtains aqueous-phase material；
(5) it prepares finished product: oil phase thing is added in aqueous-phase material, Lavender, refined jasmine oil, sea are added after being cooled to 50 DEG C
Algae zymolyte and coypu collagen, with blender high-speed stirred；PH to 6.0 is adjusted, homogeneous 10min is cooled to room temperature；It will
Extracting solution is placed in be aged 1 day at room temperature, and finished product shin moisturizer is obtained after filling.
(6) silk mask is prepared into using silk as face paper using shin moisturizer as facial mask stoste.
People by products of the present invention to 100 different occupations tries out, and following is than more typical case:
Case 1: Mr. Lin, female, 25 years old, certain troupe performer, due to often performing, needs color make-up, the frequent skin after makeup removing on the face
Skin is very dry, sometimes also has allergic phenomena, and face itches；The silk mask prepared using the embodiment of the present invention 3, is unloaded daily
Face is applied after adornment face cleaning.It is tender smooth just to have restored water for skin after 1 month, and seldom occurs allergic phenomena again, when makeup also not
Feel so dry.
Case 2: Zhang, female, 38 years old, city cleaner, due to working principle, it is small that the daily solarization time is no less than 3~4
When, especially winter will work in cold wind all day, and there are many permanent previous skin problem, and skin is very black, and pore is very big, skin
Coarse dark yellow, frequent water shortage, greasy, also produces wrinkle gradually on the face.Everybody has a love of beauty, she has used this hair later
The spraying stoste that bright shin moisturizer is prepared into, takes with oneself daily, simple and convenient toward spraying on the face when needs, 2 months it
Skin has very big improvement on the face afterwards, and the colour of skin is also white much, and wrinkle has also obtained very big alleviation.
Case 3: Wu, male, road construction person, 33 years old, working environment dust was big, and solarization is more, on the face at regular intervals
With regard to president's small pox, not only influence skin beauty, also easily infected under such working environment, just started he not how
Meaning, later every vice-minister's acne is increasingly severe, just goes to hospital to open drug therapy and just fully recovers.Doctor suggests usually maintaining more,
Not so may be more serious, it is ignorant of how maintaining really as unmarried male Wu, later accident is introduced through friend to be made
It with shin moisturizer of the invention, is used after face cleaning daily morning and evening, is used cooperatively silk mask of the invention, skin after one month again at night
Skin problem is very significantly improved, and former every month can all have two weeks or more to overwork small pox on the face, during which only long once
Small pox, symptom are also substantially reduced；Adhere to that not only skin is white using after 2 months, the colour of skin might as well be very much, most important
It is to perplex his small pox of many years really to fully recover.
Claims (7)
1. the shin moisturizer of a kind of collagen containing coypu and seaweed zymolyte, it is characterised in that: including following components: coypu
Collagen, seaweed zymolyte, Sweet Almond Oil, Lavender, refined jasmine oil, saualane, 1,3 butylene glycol, polyethylene glycol,
Polysorbas20, panthenol, xanthan gum, tocopherol, allantoin, hyaluronic acid, EDTA-2Na, deionized water.
2. the shin moisturizer of collagen containing coypu according to claim 1 and seaweed zymolyte, it is characterised in that: each group
Divide by weight percentage are as follows: coypu collagen 0.1~10%, seaweed zymolyte 0.1~10%, Sweet Almond Oil 0.05~
2%, Lavender 0.05~2%, refined jasmine oil 0.05~2%, saualane 1~10%, 1,3-BDO 1~10%, polyethylene glycol
1~8%, polysorbas20 1~5%, panthenol 0.5~5%, xanthan gum 0.5~5%, tocopherol 0.1~4%, allantoin 0.05~4%, thoroughly
Bright matter acid 0.05~5%, EDTA-2Na 0.05~2%, surplus are deionized water.
3. the shin moisturizer of collagen containing coypu according to claim 1 or 2 and seaweed zymolyte, it is characterised in that:
Preparation method includes the following steps:
(1) prepare coypu collagen: taking and cleaned with clear water after fresh furskin of nutria unhairing, removal of impurities, according to solid-liquid ratio 1:8~
10 are added the EDTA solution of 0.2mo1/L, impregnate 6~7h and remove non-collagen；It takes out furskin of nutria and 2000U/g is added
5~10% citric acid solution is added according to solid-liquid ratio 1:16~20 for pepsin, impregnates 24~48h and extracts；It filters
To collagen extracting solution, it is 0.9mol/L that sodium chloride to its concentration is added into extracting solution, and saltout 20~28h, and centrifugation obtains
Collagen deposit object puts the precipitate in the bag filter that trapped molecular weight is 10kD the 20~28h that dialyses, is lyophilized spare；
(2) it preparing seaweed zymolyte: seaweed being cleaned, drying, crush the algae powder for 50~100 mesh, every 1g algae powder is added 500~
The enzyme and 100mL water of l000U/g is uniformly mixed, maintains the temperature at 30~60 DEG C, extract 12~24 hours under oscillating condition, from
10~20min of the heart rotates after suction filtration, seaweed zymolyte is obtained after freeze-drying；
(3) it prepares oil phase thing: Sweet Almond Oil, saualane being added by weight percentage, is heated to 70~75 under stirring condition
DEG C, so that it is fused into liquid, obtains oil phase thing；
(4) prepare aqueous-phase material: in another container by weight percentage by 1,3 butylene glycol, polyethylene glycol, polysorbas20, panthenol,
Xanthan gum, tocopherol, allantoin, hyaluronic acid, EDTA-2Na are uniformly mixed, and deionized water is added, is heated under stirring condition
It 70~75 DEG C, is allowed to be completely dissolved, obtains aqueous-phase material；
(5) it prepares finished product: oil phase thing is added in aqueous-phase material, Lavender, jasmine essence are added after being cooled to 40~50 DEG C
Oil, seaweed zymolyte and coypu collagen, with blender high-speed stirred；Adjusting pH to 5.0~6.0, homogeneous 10~
30min is cooled to room temperature；Extracting solution is placed in and is aged 1~3 day at room temperature, finished product shin moisturizer is obtained after filling.
4. the shin moisturizer of collagen containing coypu according to claim 3 and seaweed zymolyte, it is characterised in that: step
(2) seaweed described in includes the combination of one or more of brown alga, red algae, green alga.
5. the shin moisturizer of collagen containing coypu according to claim 1 or 2 and seaweed zymolyte, it is characterised in that:
Enzyme described in step (2) is the one or more of alkali protease, cellulase, pentosan complex enzyme, cellulose complex enzyme
Combination.
6. the shin moisturizer of collagen containing coypu according to claim 1 and seaweed zymolyte, it is characterised in that: described
Application of the shin moisturizer in terms of preparing facial mask.
7. the shin moisturizer of collagen containing coypu according to claim 1 and seaweed zymolyte, it is characterised in that: described
Application of the shin moisturizer in terms of preparing skin care item or cosmetics.
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Application publication date: 20190719 |