CN110012903A - Can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation and preparation method thereof - Google Patents
Can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation and preparation method thereof Download PDFInfo
- Publication number
- CN110012903A CN110012903A CN201910240897.8A CN201910240897A CN110012903A CN 110012903 A CN110012903 A CN 110012903A CN 201910240897 A CN201910240897 A CN 201910240897A CN 110012903 A CN110012903 A CN 110012903A
- Authority
- CN
- China
- Prior art keywords
- parts
- essential oil
- prevention
- plants essential
- new merit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
- A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
Abstract
The invention discloses it is a kind of can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, the component including following parts by weight: 2-20 parts of Thymol, 1-5 parts of eugenol, 1-5 parts of methyl eugenol, 2-10 parts of carvacrol, 1-20 parts of cinnamic acid, 0.1-1.0 parts of sanguinarine, 0.1-1.0 parts of Chelerythrine, 40-70 parts of auxiliary material and 30-60 parts of emulsifier.Composite plant essential oil micro-capsule provided by the invention can effective prevention and control chicken new merit trombiculid, and effectively inhibit other harmful bacterial growths, promote beneficial bacteria growth, and can quickly repair lesion, make to influence in the production and sales of light chicken from skin disease caused by new merit trombiculid.
Description
Technical field
The present invention relates to chicken vermin field, more particularly to it is a kind of can the new merit chigger disease of prevention and control plants essential oil micro-capsule
Preparation and preparation method thereof.
Background technique
New merit chigger disease is as caused by the parasitized larvae of new merit trombiculid, and main parasitic is on the inside of wing, chest two sides
On inboard leg skin, especially with the chick body surface most easy infection after putting in a suitable place to breed.Once its chicken infected harm of the larva of this trombiculid
Property is very big.So that chicken group is played listless, material reducing, and it is visible on the inside of the abdomen of most of chicken, chest side, wing, neck, back etc. cover with
Black pimple causes to shed feathers.Since skin is constantly stimulated, causes pain, itch and uneasy, cause chicken development by
Resistance, gradually thin, spirit is tired, lethal can seriously die, and causes economic loss to poultry family.DDVP, pungent is currently mainly used
The pesticides such as sulphur phosphorus, fenvalerate are prevented and treated, these pesticides have compared with high toxicity, and medical fluid is not sprayable excessive, and there is a possibility that
Water body drinking water, feed, apparatus etc. are contaminated, if medical fluid is directly taken in by chicken, also have the danger for leading to poisoning.And it should
It is difficult to degrade after class Pesticide use, there are problems that pesticide residue, seriously pollute environment.
Current cultivation situation, it is desirable that broiler feeding enterprise from traditional hair chicken sales mode rapidly to fresh, chilled and
The direction of deep processing makes the transition.In the production and sales of light chicken, skin disease caused by new merit trombiculid is the important of influence product quality
One of disease.
Plants essential oil be extraction the distinctive aromatic substance of plant, be taken from herbal flower, leaf, root, bark, fruit,
What seed, resin etc. were extract to distill, in a manner of squeezing.Essential oil has the ingredient of Antimicrobial preservative, so it has antibacterial, resists micro- life
Object and antiviral characteristic.Wherein volatile oil facilitate reinforce body immune system, help resist various germs, virus
Attack.Plants essential oil shows to tag, fumigate, repellent, luring, food refusal, ovicidal, inhibits growth and development, produces to insect and mite class
A variety of modes of action such as ovum deterrent, insect especially low to ossification intensity, mite class, nematode, there is stronger function and effect.At present
At home and abroad there are no control the new merit chigger disease of chicken with plants essential oil and report for the similar microcapsule formulation of the new merit trombiculid of chicken.
New merit trombiculid is liked colonizing in the delicacy of the skins such as the wing inside of chicken, leg two sides, wet place, and infection site is logical
Often covered by thick feather.If most of medical fluid can be by chicken back from top to down by medical fluid toward sprinkling with chicken
Feather stopped, site of pathological change can not be touched, do not play drug action at all.Corrrect usage should spray drug
It is sprinkled upon on padding, when chicken squats down, site of pathological change can directly contact medical fluid, so that drug can kill the young mite of infection site
It goes out.Plants essential oil is sprayed in the padding of morbidity chicken group, the effect of desinsection, antibacterial can also enhance the drug effect of padding, and can promote
Into the healing of lesion.
Microcapsule formulation is cyst membrane to be prepared, by solid or liquid using natural or synthesis high molecular material as capsule material
Drug is wrapped up or is inlayed together, using spray congealing suspension granulating technique, forms microencapsulation.Microcapsule formulation ensure that all
Active constituent is effectively protected in microcapsules, and the active constituent energy slow release of essential oil persistently plays a role.
Therefore, need to study it is a kind of efficiently, safety, persistent can the new merit chigger disease of prevention and control chicken plants essential oil micro-capsule
Preparation, and combine the parasitized larvae feature of the new merit trombiculid of chicken and chicken production, living habit to grind chicken and produce long living habit research medicine
Object optimal use scheme keeps drug long-lasting use, easy to use.
Summary of the invention
The object of the present invention is to provide it is a kind of efficiently, safety can the new merit chigger disease of prevention and control chicken plants essential oil micro-capsule system and
Preparation method；The plants essential oil micro-capsule system combines the parasitized larvae feature and chicken production, living habit research of the new merit trombiculid of chicken
Drug optimal use scheme, and have extraordinary antibacterial effect makes drug safety, green, efficiently, has no toxic side effect and nonreactive
Pharmacological property, noresidue, no incompatibility.
To achieve the goals above, the technical solution adopted by the present invention is that:
It is a kind of can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, the component including following parts by weight: thyme
2-20 parts of phenol, 1-5 parts of eugenol, 1-5 parts of methyl eugenol, 2-10 parts of carvacrol, 1-20 parts of cinnamic acid, sanguinarine 0.1-1.0
Part, 0.1-1.0 parts of Chelerythrine, 40-70 parts of auxiliary material and 30-60 parts of emulsifier.
Preferably, it is described can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, the component including following parts by weight:
5-15 parts of Thymol, 1-3 parts of eugenol, 1-3 parts of methyl eugenol, 2-8 parts of carvacrol, 1-10 parts of cinnamic acid, sanguinarine
0.1-1.0 parts, 0.1-1.0 parts of Chelerythrine, 40-60 parts of auxiliary material and 30-50 parts of emulsifier.
Preferably, the auxiliary material is selected from rilanit special, oil with hydrogenated soybean, stearic acid, glycerin monostearate, glycerol
Monoesters, solid fat, stearyl alcohol, polyethylene glycol, Arabic gelatin, wax class, silica, soluble starch, calcium carbonate and phosphoric acid
One or more of hydrogen calcium.
Preferably, the emulsifier is selected from Tween 80, polysorbate60, polysorbas20, sorbester p18, sorbester p17, span 85, hydrogenates and gather
One or more of ethylene oxide castor oil and Emulsifier EL-60.
It is a kind of can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation preparation method, comprising the following steps:
(1) by emulsifier heating and melting, it is mixed that Thymol, eugenol, methyl eugenol, carvacrol and cinnamic acid is added
It closes, obtains emulsion；
(2) it by auxiliary material heating and melting, is added in emulsion, obtains mixture；
(3) by granulating mixture to get can the new merit chigger disease of prevention and control microcapsule formulation.
Preferably, in step (1), the temperature of emulsifier heating and melting is 60-120 DEG C；Using blender by emulsifier, hundred
In fragrant phenol, eugenol, methyl eugenol, carvacrol and cinnamic acid be stirred, the revolving speed of stirring is 40-60r/min, and the time is
0.5-1 hours.
Preferably, in step (2), the temperature of auxiliary material heating and melting is 80-100 DEG C, is sheared using cutter, the time
For 20min-40min.
Preferably, in step (3), mixture is cooled to 60-70 DEG C, is the spray of 1500-2000r/min low speed by revolving speed
Mist granulator granulation, be cooled to room temperature, obtained after sieving partial size be 100-350 μm can the new merit chigger disease of prevention and control plants essential oil
Microcapsule formulation.
It is highly preferred that sieving after obtain partial size be 100-180 μm can the new merit chigger disease of prevention and control plants essential oil micro-capsule system
Agent.
The method have the benefit that:
L, composite plant essential oil micro-capsule provided by the invention can effective prevention and control chicken new merit trombiculid, and effectively inhibit other nocuousness
Bacterial growth promotes beneficial bacteria growth, and can quickly repair lesion, makes to cause in the production and sales of light chicken from new merit trombiculid
Skin disease influence.
2, it is provided by the invention can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, principle active component is in microcapsules
In be valid protected, stability is good, it is easily stored and transport.
3, it is provided by the invention can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, have a slow releasing function, solve plant
The readily volatilized disadvantage for causing product content unstable of essential oil makes the permanent effective of active ingredients of essential oils, slow release.
4, it is of the invention can the new merit chigger disease of prevention and control chicken plants essential oil microcapsule formulation, posted in conjunction with the larva of the new merit trombiculid of chicken
Raw feature and chicken production, living habit research drug go out optimal use scheme, plants essential oil micro-capsule 1kg equably broadcast sowing in
On 200 square metres of padding, every the processing chicken group of medication in 2 weeks or so, problem control is eliminated in budding state, strives for chicken group not
Morbidity, or morbidity can rapid healing, so that chicken listing forequarter light is not influenced light chicken and is butchered, listing forequarter can restore
To normal level.
5, it is provided by the invention can the plants essential oil microcapsule formulation of the new merit chigger disease of prevention and control can substitute Pesticide use completely,
Solves the problems, such as the safety problem of pesticide residue and Pesticide use caused by being difficult to after Pesticide use degrade.
6, it is provided by the invention can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, micro-capsule surface is smooth, and color is equal
Even, particle size is 100-350 μm, is had preferable mobility and dispersed, and be to make particle glue by high speed microcapsule suspension
Capsule technology is made, and with distributed components, the uniform feature of granular size, the content for overcoming ordinary preparation is uniformly different
Problem.
Specific embodiment
In order to make the objectives, technical solutions and advantages of the present invention clearer, below by embodiment, to the present invention into
Row is further described.However, it should be understood that the specific embodiments described herein are merely illustrative of the present invention, and do not have to
In limiting the scope of the invention.
Embodiment 1
A kind of plants essential oil microcapsule formulation of the new merit chigger disease of prevention and control, the component including following parts by weight:
A kind of preparation method of the plants essential oil microcapsule formulation of the new merit chigger disease of prevention and control, comprising the following steps:
(1) each component is weighed in parts by weight；
(2) Tween 80, hydrogenation Emulsifier EL-60 are heated to 60 DEG C of thawings, Thymol, eugenol, methyl is added
Eugenol, carvacrol, cinnamic acid, sanguinarine, Chelerythrine use revolving speed to be stirred 0.5 for the blender of 40r/min
Hour, the emulsion stirred evenly；
(3) soluble starch, Macrogol 6000 and stearic acid are heated to temperature is 80 DEG C, and the cream of step (2) is added
Change in liquid, is sheared using cutter, time 30min obtains homogeneous material；
(4) the resulting homogeneous material of step (3) is 60 DEG C cooling, it is pelletized by the low velocity spray that revolving speed is 2000r/min
Mechanism grain；
(5) be cooled to room temperature, obtained after sieving partial size be 100-350 μm can the new merit chigger disease of prevention and control the precise and tiny capsule of plant
Preparation.
Embodiment 2
A kind of plants essential oil microcapsule formulation of the new merit chigger disease of prevention and control, the component including following parts by weight:
It is a kind of can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation preparation method, comprising the following steps:
(1) each component is weighed in parts by weight；
(2) Tween 80 and hydrogenation Emulsifier EL-60 are heated to 60 DEG C of thawings, Thymol, eugenol, first is added
Base eugenol, carvacrol, cinnamic acid, sanguinarine and Chelerythrine use revolving speed to be stirred for the blender of 40r/min
0.5 hour, the emulsion stirred evenly；
(3) soluble starch, Macrogol 6000 and stearic acid are heated to temperature is 80 DEG C, and the cream of step (2) is added
Change in liquid, is sheared using cutter, time 30min obtains homogeneous material；
(4) step (3) resulting homogeneous material is cooled to 60 DEG C, the low velocity spray system for being 2000r/min by revolving speed
Grain mechanism grain；
(5) be cooled to room temperature, obtained after sieving partial size be 100-350 μm can the new merit chigger disease of prevention and control the precise and tiny capsule of plant
Preparation.
Comparative example 1
A kind of powder of plants essential oil, including following parts by weight component:
A kind of preparation method of the powder of plants essential oil, comprising the following steps:
(1) each component is weighed according to parts by weight；
(2) by Thymol, eugenol, methyl eugenol, carvacrol, cinnamic acid, sanguinarine and Chelerythrine with can
The powder that soluble starch is uniformly mixed to get plants essential oil.
Beneficial effects of the present invention are described further below by way of test example.
Test example 1: can the new merit chigger disease of prevention and control plant precise and tiny capsule preparation uniformity of dosage units detection
1 test objective: prove it is provided by the present invention can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation content it is equal
Evenness reaches prescribed requirement.
2 test specimens: according to prepared by embodiment 1-2 can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, batch
It number is respectively 17051201,17051202 and comparative example 1.
3 test methods: according to " Republic of China Veterinary Pharmacopoeia one " (version in 2015) annex 166, uniformity of dosage units
Thymol uniformity of dosage units in inspection technique and inspection composite plant essential oil micro-capsule.Totally three batches, each batch take ten samples
Product carry out in accordance with the law.
4 test results are shown in Table 1
Table 1 can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation uniformity of dosage units result
Note: conclusion standard: mixture homogeneity≤15.0
Test example 1 the result shows that, it is provided by the present invention can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation content
The uniformity meets regulation, uniform properties.And its mixture homogeneity of the powder of the plants essential oil of general formulation is in comparative example 1
15.53, it is greater than 15.0, mixture homogeneity is against regulation, and content property is uneven.
Test example 2: can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation study on the stability (accelerated test)
Test objective: prove it is provided by the present invention can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation it is effective at
Divide and be valid protected in microcapsules, stability is good, easily stored and transport.
Trial drug: according to prepared by embodiment 1-2 can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, lot number
Respectively 17051201,17051202 and comparative example 1.
Test method: referring to the accelerated test measurement in one stability of " Republic of China Veterinary Pharmacopoeia " version in 2015
Method is detected.By commercially available back, at 40 DEG C ± 2 DEG C of temperature, 6 months are placed under conditions of relative temperature 70% ± 5%, in real time
Monitor temperature and humidity, 1st month during test, 2 months, 3 months, 6 the end of month it is separately sampled primary, detect the embodiment of the present invention
Can the plants essential oil microcapsule formulation of the new merit chigger disease of prevention and control and the content of the Thymol in comparative example 1.
Test result is shown in Table 2
A kind of plants essential oil microcapsule formulation stable content of the new merit chigger disease of the prevention and control of table 2 investigates result
Note: conclusion standard: content labelled amount >=90%
Test example 2 the result shows that, it is provided by the present invention can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation pass through
At 40 DEG C ± 2 DEG C of temperature, accelerated test under the conditions of relative temperature 70% ± 5%, content remains to reach on standard regulation,
Effective component is valid protected in microcapsules, and stability is good, easily stored and transport.And a kind of plants essential oil of general formulation
Powder crosses 6 months accelerated tests, and content has descended to standard value or less.
The new merit chigger disease test of prevention and control:
Test one:
Certain for taking the new non-medication of merit trombiculid of severe infections puts broiler chicken chicken house in a suitable place to breed (disease incidence is about 70%, individual lesion up to 3
More than place).Plants essential oil micro-capsule 1kg is equably broadcasted sowing respectively in 100 square metres, 200 square metres, 300 square metres of padding
On, every the processing chicken group of medication in 2 weeks or so.
Before medication the 5th day after 1 day and medication, 20 chickens of the 10th day each random inspection record new merit trombiculid lesion quantity,
And repair situation.
By above data we it can be concluded that, plants essential oil micro-capsule 1kg is equably broadcasted sowing respectively in 100 square metres and 200
It so that new merit trombiculid lesion is formed a scab in square metres 5 days, in 10 days new merit trombiculid lesion can repaired completely.Plants essential oil is micro-
Capsule 1kg equably broadcast sowing it is poor in 300 square metres of padding effect, so selection plants essential oil micro-capsule 1kg equably broadcast sowing in
It is optimal operational version on 200 square metres of padding.
Test two:
Certain of the non-medication of the new merit trombiculid of severe infections puts broiler chicken chicken house in a suitable place to breed, and (disease incidence is about 70%, individual lesion up to 3
More than place).Taking tri- henhouse areas of A, B, C is all 410 squares, raises 4600 broiler chicken respectively, opens after 2 days after changing new padding
Beginning medication.
Grouping: A control group, B is phoxim medicine group, and C is plants essential oil micro-capsule group.
Therapeutic regimen: A is not added medicine group, and B 40% solution medical fluid of phoxim is watered in sprinkling henhouse by 1:4000 and is padded
Expect and sprayed with chicken, C takes plants essential oil microcapsule formulation 1kg equably to broadcast sowing on 200 square metres of padding.
Before medication the 5th day after 1 day and medication, 20 chickens of the 10th day each random inspection record new merit trombiculid lesion quantity,
And repair situation.
As can be seen from the above data, it is provided by the invention can the plants essential oil microcapsule formulation of the new merit chigger disease of prevention and control kill
Mite effect is obviously also better than 40% solution of phoxim, and phoxim is big using rear smell, the most of chicken of toxicity spirit occurs and sinks
It is strongly fragrant.The 5th day new merit trombiculid lesion starts to form a scab and fall after plants essential oil microcapsule formulation medication, new merit trombiculid lesion reparation in the 10th day
It is intact, there is the ability for quickly repairing lesion, make to influence in the production and sales of light chicken from skin disease caused by new merit trombiculid.
Claims (8)
1. one kind can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, which is characterized in that the group including following parts by weight
Point: 2-20 parts of Thymol, 1-5 parts of eugenol, 1-5 parts of methyl eugenol, 2-10 parts of carvacrol, 1-20 parts of cinnamic acid, red root
0.1-2 parts of alkali, 0.1-2 parts of Chelerythrine, 40-70 parts of auxiliary material and 30-60 parts of emulsifier.
2. it is according to claim 1 can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, which is characterized in that including with
The component of lower parts by weight: 5-15 parts of Thymol, 1-3 parts of eugenol, 1-3 parts of methyl eugenol, 2-8 parts of carvacrol, cortex cinnamomi
1-10 parts of aldehyde, 0.1-1.0 parts of sanguinarine, 0.1-1.0 parts of Chelerythrine, 40-60 parts of auxiliary material and 30-50 parts of emulsifier.
3. it is according to claim 1 can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, which is characterized in that it is described auxiliary
Material is selected from rilanit special, oil with hydrogenated soybean, stearic acid, glycerin monostearate, monoglyceride, solid fat, stearyl alcohol, poly- second
One or more of glycol, Arabic gelatin, wax class, silica, soluble starch, calcium carbonate and calcium monohydrogen phosphate.
4. it is according to claim 1 can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation, which is characterized in that the cream
Agent is selected from Tween 80, polysorbate60, polysorbas20, sorbester p18, sorbester p17, span 85, hydrogenation Emulsifier EL-60 and polyoxy second
One or more of alkene castor oil.
5. it is of any of claims 1-4 can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation preparation method,
Characterized by comprising the following steps:
(1) by emulsifier heating and melting, Thymol, eugenol, methyl eugenol, carvacrol and cinnamic acid mixing is added, obtains
To emulsion；
(2) it by auxiliary material heating and melting, is added in emulsion, obtains mixture；
(3) by granulating mixture to get can the new merit chigger disease of prevention and control microcapsule formulation.
6. preparation method according to claim 5, which is characterized in that in step (1), the temperature of the emulsifier heating and melting
Degree is 60-120 DEG C；Emulsifier, Thymol, eugenol, methyl eugenol, carvacrol and cinnamic acid are stirred using blender
Mixing, the revolving speed of stirring are 40-60r/min, and the time is 0.5-1 hours.
7. preparation method according to claim 5, which is characterized in that in step (2), the temperature of the auxiliary material heating and melting
It is 80-100 DEG C, is sheared using cutter, time 20min-40min.
8. preparation method according to claim 5, which is characterized in that in step (3), mixture is cooled to 60-70 DEG C,
It is the granulation of 1500-2000r/min low velocity spray granulator by revolving speed；It is cooled to room temperature, it is 100-350 that partial size is obtained after sieving
μm can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910240897.8A CN110012903A (en) | 2019-03-28 | 2019-03-28 | Can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910240897.8A CN110012903A (en) | 2019-03-28 | 2019-03-28 | Can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110012903A true CN110012903A (en) | 2019-07-16 |
Family
ID=67190166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910240897.8A Pending CN110012903A (en) | 2019-03-28 | 2019-03-28 | Can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110012903A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113498783A (en) * | 2021-06-28 | 2021-10-15 | 佛山市正典生物技术有限公司 | Mite-killing missible oil and preparation method and application thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11335218A (en) * | 1998-05-21 | 1999-12-07 | Sekisui Chem Co Ltd | Acaricide |
| CN1718005A (en) * | 2005-04-11 | 2006-01-11 | 西北农林科技大学 | Plant extract used as miticide |
| CN102078313A (en) * | 2011-01-06 | 2011-06-01 | 西北农林科技大学 | High-efficiency, low-toxicity and safe plant source acaricidal medicament and preparation method thereof |
| CN102180885A (en) * | 2011-03-31 | 2011-09-14 | 西北农林科技大学 | Sanguinarine alcoholate and chelerythrine alcoholate and preparation method and application thereof in animal acaricidal drugs |
| CN105726523A (en) * | 2016-04-08 | 2016-07-06 | 中国农业科学院兰州畜牧与兽药研究所 | Drug composition for treating animal acariasises and preparation method and application thereof |
| CN108135862A (en) * | 2015-07-21 | 2018-06-08 | 瓦伦西亚理工大学 | Antibacterial, deinsectization, mite killing system |
-
2019
- 2019-03-28 CN CN201910240897.8A patent/CN110012903A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11335218A (en) * | 1998-05-21 | 1999-12-07 | Sekisui Chem Co Ltd | Acaricide |
| CN1718005A (en) * | 2005-04-11 | 2006-01-11 | 西北农林科技大学 | Plant extract used as miticide |
| CN102078313A (en) * | 2011-01-06 | 2011-06-01 | 西北农林科技大学 | High-efficiency, low-toxicity and safe plant source acaricidal medicament and preparation method thereof |
| CN102180885A (en) * | 2011-03-31 | 2011-09-14 | 西北农林科技大学 | Sanguinarine alcoholate and chelerythrine alcoholate and preparation method and application thereof in animal acaricidal drugs |
| CN108135862A (en) * | 2015-07-21 | 2018-06-08 | 瓦伦西亚理工大学 | Antibacterial, deinsectization, mite killing system |
| CN105726523A (en) * | 2016-04-08 | 2016-07-06 | 中国农业科学院兰州畜牧与兽药研究所 | Drug composition for treating animal acariasises and preparation method and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 朱峰 等: ""农药微囊剂及其制备技术研究进展"", 《现代农药》 * |
| 郑峰: ""血根碱和白屈菜红碱及其衍生物的抑菌和杀螨活性"", 《中国优秀硕士学位论文全文数据库（工程科技I辑）》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113498783A (en) * | 2021-06-28 | 2021-10-15 | 佛山市正典生物技术有限公司 | Mite-killing missible oil and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN112189763A (en) | Preparation process and application of plant essential oil microcapsule | |
| CN109833296A (en) | Can the new merit chigger disease of prevention and control plants essential oil microemulsion formulation and preparation method thereof | |
| CN110012903A (en) | Can the new merit chigger disease of prevention and control plants essential oil microcapsule formulation and preparation method thereof | |
| CN109329610A (en) | A kind of feed addictive and preparation method thereof for pig | |
| CN110495420B (en) | Method for preventing and treating red mites of poultry | |
| CN106689186A (en) | Efficient insecticidal composition containing bifenthrin and pyriproxyfen | |
| CN108719345B (en) | Origanum vulgaris essential oil preparation, preparation method and application thereof | |
| CN103739394A (en) | Biogas liquid compounded fungicide for preventing and treating gray mold | |
| KR20190099751A (en) | Compositions for controlling poultry red mite comprising extracts derived from natural materials and preparation method of the same | |
| CN112400917B (en) | Tick-expelling composition | |
| CN109999014A (en) | It is a kind of can the new merit chigger disease of prevention and control plants essential oil and preparation method thereof | |
| CN108812707A (en) | One kind killing thrips plant essential oil composition, preparation and its application | |
| CN113498783A (en) | Mite-killing missible oil and preparation method and application thereof | |
| CN104604896B (en) | A kind of composition, preparation and its application for preventing and kill off semen cuscatue spp parasitic plant | |
| CN102318648B (en) | Macleaya cordata total alkaloids flea-killing spraying agent | |
| CN106342854A (en) | Pesticide composition | |
| CN105961446A (en) | Compound-type nano rodent repellent and use method thereof | |
| CN108670948A (en) | A kind of nanoscale micro-capsule unimolecule Betagen Solution and preparation method thereof | |
| CN105309441B (en) | Composition pesticide containing nitrile pyrrole mite ester and its purposes in prevention and treatment harmful mite | |
| MXPA05005197A (en) | Combination product for controlling insect pests. | |
| RU2729742C1 (en) | Method of producing an insectoacaricidal concentrate for plant protection | |
| CN103755471A (en) | Biogas slurry compound bactericide for preventing and treating leaf mold | |
| CN102578114A (en) | Pesticide composite containing emamectin benzoate and tebufenozide | |
| KR20170109936A (en) | Pesticide Composition for Aphid | |
| CN112972437B (en) | Long-acting external preparation containing iodonitrophenol and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190716 |
|
| RJ01 | Rejection of invention patent application after publication |