CN102318648B - Macleaya cordata total alkaloids flea-killing spraying agent - Google Patents
Macleaya cordata total alkaloids flea-killing spraying agent Download PDFInfo
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- CN102318648B CN102318648B CN 201110187071 CN201110187071A CN102318648B CN 102318648 B CN102318648 B CN 102318648B CN 201110187071 CN201110187071 CN 201110187071 CN 201110187071 A CN201110187071 A CN 201110187071A CN 102318648 B CN102318648 B CN 102318648B
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- Prior art keywords
- flea
- macleaya cordata
- spraying agent
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- cordata total
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- 240000007849 Macleaya cordata Species 0.000 title claims abstract description 28
- 229930013930 alkaloid Natural products 0.000 title claims abstract description 26
- 238000005507 spraying Methods 0.000 title claims abstract description 17
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 25
- 239000002904 solvent Substances 0.000 claims abstract description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 13
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 10
- 229910052710 silicon Inorganic materials 0.000 claims description 10
- 239000010703 silicon Substances 0.000 claims description 10
- -1 siloxanes Chemical group 0.000 claims description 10
- 239000004094 surface-active agent Substances 0.000 claims description 10
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 9
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical group OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 9
- 230000000740 bleeding effect Effects 0.000 claims description 6
- 239000000470 constituent Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical group ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 claims description 5
- 150000003797 alkaloid derivatives Chemical class 0.000 claims description 5
- 229960002415 trichloroethylene Drugs 0.000 claims description 3
- UBOXGVDOUJQMTN-UHFFFAOYSA-N trichloroethylene Natural products ClCC(Cl)Cl UBOXGVDOUJQMTN-UHFFFAOYSA-N 0.000 claims description 3
- 241000282326 Felis catus Species 0.000 abstract description 8
- 239000002994 raw material Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 239000002917 insecticide Substances 0.000 abstract description 5
- 150000002903 organophosphorus compounds Chemical class 0.000 abstract description 4
- 239000000126 substance Substances 0.000 abstract description 4
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- YREQHYQNNWYQCJ-UHFFFAOYSA-N etofenprox Chemical compound C1=CC(OCC)=CC=C1C(C)(C)COCC1=CC=CC(OC=2C=CC=CC=2)=C1 YREQHYQNNWYQCJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002085 irritant Substances 0.000 abstract 1
- 231100000021 irritant Toxicity 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000002357 osmotic agent Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 241000009328 Perro Species 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 5
- 238000003756 stirring Methods 0.000 description 4
- 241000723353 Chrysanthemum Species 0.000 description 3
- 235000007516 Chrysanthemum Nutrition 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 241000258242 Siphonaptera Species 0.000 description 2
- 125000001931 aliphatic group Chemical group 0.000 description 2
- 239000007859 condensation product Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 230000003449 preventive effect Effects 0.000 description 2
- 230000001932 seasonal effect Effects 0.000 description 2
- 241000490513 Ctenocephalides canis Species 0.000 description 1
- 206010012434 Dermatitis allergic Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- OEBRKCOSUFCWJD-UHFFFAOYSA-N dichlorvos Chemical compound COP(=O)(OC)OC=C(Cl)Cl OEBRKCOSUFCWJD-UHFFFAOYSA-N 0.000 description 1
- 229950001327 dichlorvos Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 210000004919 hair shaft Anatomy 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000009191 jumping Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229960001952 metrifonate Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000016087 ovulation Effects 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- NFACJZMKEDPNKN-UHFFFAOYSA-N trichlorfon Chemical compound COP(=O)(OC)C(O)C(Cl)(Cl)Cl NFACJZMKEDPNKN-UHFFFAOYSA-N 0.000 description 1
- 239000000273 veterinary drug Substances 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a Macleaya cordata total alkaloids flea-killing spraying agent, which comprises the following components: 0.1 percent to 8 percent of Macleaya cordata total alkaloids, 3 percent to 12 percent of sasanguasaponin, 1 percent to 13 percent of osmotic agent and the rest of solvent. The flea-killing spraying agent has an obvious effect, the prevention effect can reach 100 percent, the flea-killing spraying agent can substitute the present chemical organophosphorous compound and ethofenprox flea-killing products, has no unfavorable smell, is friendly to the environment, and is non-toxic to the skin of the human beings, cats and dogs. Compared with the traditional insecticide, main raw materials of the Macleaya cordata total alkaloids flea-killing spraying agent are from nature, the use effect is good, and the flea-killing spraying agent is non-irritant to the skin.
Description
Technical field
The present invention relates to traditional Chinese medical science veterinary drug technical field, specifically a kind of Macleaya cordata total alkaloids flea-killing spraying agent.
Background technology
The pet parasitosis is one of pet common disease, and flea clinical onset rate accounts for dermopathic more than 60%.In people's living environment, the flea multiparasitism is raised in home mouse or family with it the animals such as dog, cat, at home angle, room, wall meet, under bed, also can multiply in the dust located such as adobe kang.Flea just no longer leaves after usually jumping onto the host, just can begin two days later ovulation, and female flea can lay eggs hundreds of to thousands of throughout one's life, approximately 1～2 year life-span.Flea creeps on skin, stings and sting, suck blood, and causes harassing and wrecking and stimulates, and makes people and animals' sufferings, lather, insomnia.Flea can be infected various diseases, such as allergic dermatitis, seasonal eczema etc.Seasonal eczema is shown effect sufferings unbearably, and is difficult to radical cure, can bring very large misery and inconvenient to the patient.Use to get comparatively general and with fastest developing speed being still chemical insecticide kill fleas both at home and abroad, normally used chemical insecticide is mainly organic phosphorus compound and intends chrysanthemum ester class, use these hypertoxic insecticides and not only killed insect, also destroyed living environment and damaged dog, cat and Person's skin.Use organic phosphorus compound and intend chrysanthemum lipid insecticide due to long-term, flea has produced resistance, and take organic phosphor product " chlorophos " as example, it is very low that it kills the flea effect, and " dichlorvos " even kills extremely flea.After entering 21 century, keep a cat, support the pet such as dog and become a kind of fashion, therefore a kind of low toxicity of necessary production efficient, environmentally friendly, kill the flea product to the people to cat, dog nonhazardous.
Summary of the invention
The purpose of this invention is to provide a kind of Macleaya cordata total alkaloids flea-killing spraying agent, this kills flea hydro-peening agent successful, and preventive effect can reach 100%, and alternative existing chemical organic phosphorus compound and plan chrysanthemum lipid are killed the flea product.
The present invention realizes that purpose adopts following technical scheme: a kind of Macleaya cordata total alkaloids flea-killing spraying agent comprises following component:
Macleaya cordata total alkaloid 0.1-8%
Sasanguasaponin 3-12%
Bleeding agent 1-13%
All the other are solvent.(described ratio is weight percentage)
Its active constituent content of described macleaya cordata total alkaloid is 60-80%.(described ratio is weight percentage)
Described sasanguasaponin active constituent content＞90%.(described ratio is weight percentage)
Described bleeding agent is siloxanes APEO organic silicon surfactant, in the condensation product of oxirane or higher aliphatic any one.
Described solvent is methyl alcohol, ethanol, trichloro-ethylene, ethyl acetate, or in pure water any one.
The preparation method of Macleaya cordata total alkaloids flea-killing spraying agent adds solvent in reactor with agitator, add successively macleaya cordata extracts, sasanguasaponin, bleeding agent siloxanes APEO organic silicon surfactant etc., heating to 50 ℃ stirs, and is cooled to normal temperature.Manufactured goods are packed into be with in shower nozzle pump bottle, made Macleaya cordata total alkaloids flea-killing spraying agent.
The present invention compared with prior art has following advantage: compare its main material with conventional pesticides from natural, result of use is good, and is non-stimulated to skin without bad smell, environmentally friendly, to people, cat, the nonhazardous of dogskin skin.
Result of use: make with the present invention and kill the agent of flea hydro-peening and kill flea, preventive effect can reach 100%.Below specifically described.
(1) trying out dog: dog weighs 10 kilograms, and 100 above fleas are arranged on inspection.Dog is sprayed, and completely wet, the death in 1 minute of dog flea with it checks after hair shaft and does not find the flea that lives.
(2) on probation to cat: just reach a moon kitten for 6, on inspection every about flea more than 30.With Macleaya cordata total alkaloids flea-killing spraying agent to cat with having a bath, dosage: kill flea hydro-peening agent 10ml and add 1 kilogram, water, the rear flea corpse of having a bath is all kept afloat.
Embodiment:
Composition of raw materials: below the enforcement proportioning that provides can be for reference, actual production can be selected in the proportion that the present invention gives.
The raw material explanation
1, macleaya cordata total alkaloid is the main component of macleaya cordata extracts, and its active constituent content requires to reach 60-80%.(described ratio is weight percentage)
2, sasanguasaponin active constituent content＞90%.(described ratio is weight percentage)
3, bleeding agent is siloxanes APEO organic silicon surfactant, in the condensation product of oxirane or higher aliphatic any one.
4, solvent is methyl alcohol, ethanol, trichloro-ethylene, ethyl acetate, or in pure water any one.
Embodiment 1
Raw material forms: 5 kilograms of macleaya cordata total alkaloids, 80 kilograms of sasanguasaponins, 10 kilograms of siloxanes APEO organic silicon surfactants, 905 kilograms of 85% ethanol.
Production method: it is in 2000 liters of reactors with agitator that 905 kilograms of 85% ethanol are added capacity, add successively 5 kilograms of macleaya cordata total alkaloids, 80 kilograms of sasanguasaponins, 10 kilograms of siloxanes APEO organic silicon surfactants, heat to 50 ℃ and stir, be cooled in the band shower nozzle pump bottle of packing into after normal temperature, made Macleaya cordata total alkaloids flea-killing spraying agent.
Embodiment 2
Raw material forms: 5 kilograms of macleaya cordata total alkaloids, 80 kilograms of sasanguasaponins, 10 kilograms of siloxanes APEO organic silicon surfactants, 905 kilograms of trichloro-ethylenes.
Production method: it is in 2000 liters of reactors with agitator that 905 kilograms of trichloro-ethylenes are added capacity, add successively 5 kilograms of macleaya cordata total alkaloids, 80 kilograms of sasanguasaponins, 10 kilograms of siloxanes APEO organic silicon surfactants, heat to 50 ℃ and stir, be cooled in the band shower nozzle pump bottle of packing into after normal temperature, made Macleaya cordata total alkaloids flea-killing spraying agent.
Embodiment 3
Raw material forms: 5 kilograms of macleaya cordata total alkaloids, 80 kilograms of sasanguasaponins, 10 kilograms of siloxanes APEO organic silicon surfactants, 905 kilograms of pure water.
Production method: it is in 2000 liters of reactors with agitator that 905 kilograms of pure water are added capacity, add successively 5 kilograms of macleaya cordata total alkaloids, 80 kilograms of sasanguasaponins, 10 kilograms of siloxanes APEO organic silicon surfactants, heating to 50 ℃ stirs well even, be cooled in the band shower nozzle pump bottle of packing into after normal temperature, made Macleaya cordata total alkaloids flea-killing spraying agent.
Claims (1)
1. Macleaya cordata total alkaloids flea-killing spraying agent comprises following component:
Macleaya cordata total alkaloid 0.1-8%
Sasanguasaponin 3-12%
Bleeding agent 1-13%
All the other are solvent
Its active constituent content of described macleaya cordata total alkaloid is 60-80%,
Described sasanguasaponin active constituent content＞90%;
Described bleeding agent is siloxanes APEO organic silicon surfactant;
Described solvent is methyl alcohol, ethanol, trichloro-ethylene, ethyl acetate, or in pure water any one;
Described ratio all is weight percentage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110187071 CN102318648B (en) | 2011-07-01 | 2011-07-01 | Macleaya cordata total alkaloids flea-killing spraying agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110187071 CN102318648B (en) | 2011-07-01 | 2011-07-01 | Macleaya cordata total alkaloids flea-killing spraying agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102318648A CN102318648A (en) | 2012-01-18 |
| CN102318648B true CN102318648B (en) | 2013-11-06 |
Family
ID=45446594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110187071 Active CN102318648B (en) | 2011-07-01 | 2011-07-01 | Macleaya cordata total alkaloids flea-killing spraying agent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102318648B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105395617B (en) * | 2015-11-24 | 2019-09-03 | 湖南汉清生物技术有限公司 | A kind of lavipeditum effervescent tablet and its preparation method containing macleaya cordata total alkaloid |
| CN110012909A (en) * | 2019-03-22 | 2019-07-16 | 陕西康禾立丰生物科技药业有限公司 | A kind of Pesticidal combination containing sanguinarine |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101020703A (en) * | 2006-11-01 | 2007-08-22 | 郁建生 | Total alkaloid of pink plumepoppy herb |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5133981A (en) * | 1989-11-17 | 1992-07-28 | Atrix Laboratories, Inc. | Purification of benzophenanthridine alkaloids extracts from alkaloid extracts |
-
2011
- 2011-07-01 CN CN 201110187071 patent/CN102318648B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101020703A (en) * | 2006-11-01 | 2007-08-22 | 郁建生 | Total alkaloid of pink plumepoppy herb |
Non-Patent Citations (4)
| Title |
|---|
| 博落回生物碱的研究进展;邓敦 等;《家畜生态学报》;20090715;第30卷(第4期);第7页 * |
| 油茶皂甙提纯分离和结构鉴定方法综述;靳燕 等;《化学世界》;20000525(第5期);第231页 * |
| 邓敦 等.博落回生物碱的研究进展.《家畜生态学报》.2009,第30卷(第4期),第7页. |
| 靳燕 等.油茶皂甙提纯分离和结构鉴定方法综述.《化学世界》.2000,(第5期),第231页. |
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| Publication number | Publication date |
|---|---|
| CN102318648A (en) | 2012-01-18 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Macleaya cordata total alkaloids flea-killing spraying agent Effective date of registration: 20191220 Granted publication date: 20131106 Pledgee: Agricultural Development Bank of China Chenxi County sub branch Pledgor: HUNAN HANQING BIOLOGICAL Co.,Ltd. Registration number: Y2019980001187 |
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| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131106 |