CN109998942B

CN109998942B - Multi-effect whitening composition and preparation method thereof

Info

Publication number: CN109998942B
Application number: CN201910312114.2A
Authority: CN
Inventors: 刘黎佳
Original assignee: Shanghai Liuying Trading Co ltd
Current assignee: Shanghai Liuying Trading Co ltd
Priority date: 2019-04-18
Filing date: 2019-04-18
Publication date: 2022-02-22
Anticipated expiration: 2039-04-18
Also published as: CN109998942A

Abstract

The invention discloses a multi-effect whitening composition, which at least comprises the following components in parts by weight: 30-60 parts of water, 5-15 parts of a humectant, 12-20 parts of an emollient, 0.5-3 parts of a skin conditioner, 3-10 parts of titanium dioxide, 1-5 parts of an emulsifier, 1-5 parts of a thickener and 0.5-1.5 parts of an auxiliary agent. The whitening composition has the effects of whitening, moisturizing and protecting skin; can be used on both the face and body; the whitening composition can be immediately whitened after being used, can effectively improve the skin brightness and effectively slow down the synthesis speed of melanin after being used for a long time, has safety and no irritation to the skin of a human body, and is suitable for various crowds.

Description

Multi-effect whitening composition and preparation method thereof

Technical Field

The invention relates to the field of cosmetics, in particular to a multi-effect whitening composition and a preparation method thereof.

Background

The color of human skin is developed for a variety of reasons, and the determining factor is the distribution and content of melanin. The main processes for producing melanin are: tyrosine in melanocyte tissue is converted by dopachrome, dopaquinone and dopa under the action of tyrosinase, so as to generate melanin. According to related reported researches, the sales of the whitening cosmetics in China is in an increasing mode, and the market potential is worthy of attention. Most of the prior whitening cosmetics take tyrosinase as a base, and the whitening active ingredients are used for controlling the activity of the tyrosinase, so that the formation of melanin is reduced, and the whitening effect is achieved.

At the early stage of the popularization of whitening cosmetics, although the whitening effect is very obvious, chemical substances such as hormones, mercury and the like exist, toxicity is generated on human bodies, and long-term deposition is generated, so that organs in the bodies are in failure. With the improvement of the system in the aspect of cosmetics in China, the requirements for skin whitening meet the following standards: can inhibit the activity of tyrosinase; the whitening cosmetic has high safety and no irritation to skin. The existing whitening products sacrifice the product effect in order to improve the safety, cannot balance the immediate effect and the long-term whitening, and also improve the stability of the products.

Disclosure of Invention

In order to solve the technical problems, the first aspect of the present invention provides a multi-effect whitening composition, which at least comprises the following components in parts by weight: 30-60 parts of water, 5-15 parts of a humectant, 12-20 parts of an emollient, 0.5-3 parts of a skin conditioner, 3-10 parts of titanium dioxide, 1-5 parts of an emulsifier, 1-5 parts of a thickener and 0.5-1.5 parts of an auxiliary agent.

As a preferable technical scheme, the humectant is selected from one or more of butanediol, glycerol, panthenol, sodium hyaluronate, hydrolyzed glycosaminoglycans, propylene glycol, sorbitol and polyethylene glycol.

As a preferred technical scheme, the emollient is selected from one or more of isononyl isononanoate, polydimethylsiloxane, cyclopentadimethylsiloxane, cyclohexasiloxane, octyl polydimethylsiloxane, bis-PEG-18 methyl ether dimethylsilane, cetyl PEG/PPG-10/1 polydimethylsiloxane and PEG-12 polydimethylsiloxane.

As a preferable technical scheme, the skin conditioner is one or a mixture of more of a plant composite anti-allergy agent, a Cladosiphon stardanum extract and CP 05.

As a preferable technical scheme, the plant composite anti-allergy agent is a composition consisting of butanediol, water, a centella extract, a polygonum cuspidatum root extract, a scutellaria baicalensis root extract, a tea leaf extract, a glycyrrhiza glabra root extract, a chamomile flower extract and a rosemary leaf extract.

As a preferable technical scheme, the emulsifier is one or more of potassium cetyl phosphate, polyglycerol-3 cocoate, stearate, glycerol stearate and cetyl stearyl alcohol.

As a preferred technical scheme, the thickening agent is selected from one or more of EG, xanthan gum, carbomer, polyvinyl alcohol, gelatin and carrageenan.

As a preferable technical scheme, the auxiliary agent is selected from one or more of sodium carboxymethyl cellulose, hydroxyethyl cellulose and methyl cellulose.

As a preferable technical scheme, the composition further comprises 0.05-0.2 part of essence by weight.

The second aspect of the present invention provides a preparation method of the above multi-effect whitening composition, comprising the steps of:

a. adding the pre-dispersed humectant and the auxiliary agent into a preparation pot 1 containing water, stirring and heating to 80 ℃ to be uniform;

b. sequentially adding the raw materials of the emulsifier, the emollient and the titanium dioxide into the preparation pot 2, stirring and heating to 80 ℃ to be uniform;

c. b, adding a thickening agent into the preparation pot 1 in the step a, stirring for 1-10 minutes, adding the mixed liquid obtained in the step b into the preparation pot 1, stirring for 1-10 minutes, and cooling;

d. and c, cooling to 40 ℃, adding the raw material skin conditioner into the mixture obtained in the step c, stirring uniformly, taking the materials, detecting, and directly discharging after the materials are qualified.

Has the advantages that: the whitening composition provided by the application has the effects of whitening, moisturizing and protecting skin; can be used on both the face and body; the whitening composition can be immediately whitened after being used, can effectively improve the skin brightness and effectively slow down the synthesis speed of melanin after being used for a long time, has safety and no irritation to the skin of a human body, and is suitable for various crowds.

Detailed Description

The invention will be further understood by reference to the following detailed description of preferred embodiments of the invention and the examples included therein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. To the extent that a definition of a particular term disclosed in the prior art is inconsistent with any definitions provided herein, the definition of the term provided herein controls.

As used herein, a feature that does not define a singular or plural form is also intended to include a plural form of the feature unless the context clearly indicates otherwise. It will be further understood that the term "prepared from …," as used herein, is synonymous with "comprising," including, "comprising," "having," "including," and/or "containing," when used in this specification means that the recited composition, step, method, article, or device is present, but does not preclude the presence or addition of one or more other compositions, steps, methods, articles, or devices. Furthermore, the use of "preferred," "preferably," "more preferred," etc., when describing embodiments of the present application, is meant to refer to embodiments of the invention that may provide certain benefits, under certain circumstances. However, other embodiments may be preferred, under the same or other circumstances. In addition, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, nor is it intended to exclude other embodiments from the scope of the invention.

In some preferred embodiments, the multi-effect whitening composition at least comprises the following components in parts by weight: 57 parts of water, 9.53 parts of humectant, 18 parts of emollient, 1.9 parts of skin conditioner, 6 parts of titanium dioxide, 3 parts of emulsifier, 3.5 parts of thickener and 1.2 parts of auxiliary agent.

Moisture-retaining agent

The moisturizer is a hydrophilic skin moisturizing substance, so that water molecules in cosmetics can be brought into the skin to instantly moisturize the skin, the moisture in the air can be absorbed, the long-acting moisturizing effect is achieved, the skin is kept in a good water balance state, and the dryness of the skin is relieved.

In some preferred embodiments, the humectant is selected from the group consisting of butylene glycol, glycerin, panthenol, sodium hyaluronate, hydrolyzed glycosaminoglycans, propylene glycol, sorbitol, a mixture of one or more of polyethylene glycol; further preferably, the humectant is a mixture of butylene glycol, glycerin, panthenol, sodium hyaluronate, and hydrolyzed glycosaminoglycan.

In some preferred embodiments, the weight ratio of butylene glycol, glycerin, panthenol is 5: 3: 1.

in some preferred embodiments, the weight ratio of sodium hyaluronate and hydrolyzed glycosaminoglycans is 0.3: 5.

in some preferred embodiments, the ratio of the sum of the weights of butylene glycol, glycerol, panthenol to the sum of the weights of sodium hyaluronate, hydrolyzed glycosaminoglycans is 9: 0.53.

the principle of hydrolyzed glycosaminoglycans, which may be hydrolyzed glycosaminoglycans capable of acting as a moisturizer, penetrating into the skin, promoting the synthesis of hyaluronic acid, and whitening the skin after long-term use, may be that hydrolyzed glycosaminoglycans bind ionic copper, whereas neuraminidase, a copper-binding protein, is disrupted in its binding to copper, causing it to lose its catalytic activity.

Butanediol (CAS No. 107-88-0), glycerol (CAS No. 56-81-5) in this application were purchased from German chemical company, Inc. on the sea; panthenol (CAS number: 81-13-0) was purchased from Shanghai Kazuki Limao Co., Ltd; sodium hyaluronate (CAS number: 9067-32-7) was purchased from Dongyngfosste bioengineering, Inc.; hydrolyzed glycosaminoglycans are available from Shanghai span trade development, Inc.

Skin-moistening agent

The emollient is mainly esters, and then the effective silanes appear better, and when the emollient is applied to the skin, the emollient can fill in tiny hollow spaces on the surface of the skin, replenish lipid lost in the stratum corneum and make the skin soft and smooth.

In some preferred embodiments, the emollient is selected from the group consisting of isononyl isononanoate, dimethicone, cyclopentademethicone, cyclohexasiloxane, octyldimethicone, bis-PEG-18 methyl ether dimethylsilane, cetyl PEG/PPG-10/1 dimethicone, a mixture of one or more of PEG-12 dimethicone; further preferably, the emollient is a mixture of isononyl isononanoate, polydimethylsiloxane, cyclopentadimethylsiloxane, cyclohexasiloxane, octylpolydimethylsiloxane.

In some preferred embodiments, the weight ratio of isononyl isononanoate, polydimethylsiloxane, cyclopentadimethylsiloxane, cyclohexasiloxane, octylpolydimethylsiloxane is 5: 8: 1: 1: 3.

the siloxane can be used as a skin moistening component for filling the surface of the skin and improving the appearance of the skin, has a good moisturizing effect, is not greasy when used, improves the dryness and water shortage of the skin, and regulates the water-oil balance.

Isononyl isononanoate (CAS number 42131-25-9) in the present application was purchased from German chemical Co., Ltd, on the sea; polydimethylsiloxane (CAS number: 63148-62-9), cyclopentadimethylsiloxane (CAS number: 541-02-6), cyclohexasiloxane (CAS number: 540-97-6), octylpolydimethylsiloxane (CAS number: 17955-88-3) were purchased from Shanghai Dry fly chemical Co., Ltd.

Skin conditioning agent

A skin conditioner is a component which can easily permeate into the skin, repair and condition the skin, and has the effects of whitening, resisting wrinkles, removing red blood, preventing allergy, improving skin resistance and the like.

In some preferred embodiments, the skin conditioning agent is selected from a mixture of one or more of a botanical composite anti-allergy agent, Cladosiphon stardus extract, CP 05; further preferably, the skin conditioner is a mixture of a plant composite anti-allergy agent, a Cladosiphon stardanum extract and CP 05.

In some preferred embodiments, the weight ratio of the plant composite anti-allergic agent, the cladosporium asteroides extract and the CP05 is 1: 0.5: 0.4.

the botanical composite anti-allergy agent in the present application is a composition containing a plurality of botanical extracts, and in some preferred embodiments, the botanical composite anti-allergy agent is a composition consisting of butylene glycol, water, centella asiatica extract, polygonum cuspidatum root extract, scutellaria baicalensis root extract, tea leaf extract, glycyrrhiza glabra root extract, chamomile flower extract and rosemary leaf extract.

The plant composite anti-allergy agent has the main functions of preventing skin allergy or sunburn, and the centella extract can tighten the skin, promote blood circulation, prevent pigmentation and repair the skin after being sunburned; the rhizoma Polygoni Cuspidati extract and radix Scutellariae extract have effects in clearing away heat and promoting blood circulation; the tea extract can balance the water and oil state of skin, sterilize and resist oxidation; the Glycyrrhiza glabra root extract also has antioxidant effect and can lighten skin color; the flos Matricariae Chamomillae extract can relieve injury after sunburn and relieve skin; the rosemary leaf extract has high activity antioxidant component, and can delay aging. The Cladosiphon okamuranus extract is a small molecular component, has good permeability and easy absorption, has an inhibition effect on prolyl endopeptidase, is beneficial to regulating angiotensin and neurotensin, has a relieving and antioxidant effect, can also inhibit hyaluronidase, prevent hyaluronic acid from decomposing and has a moisturizing effect.

The plant composite anti-allergic agent is purchased from Shanghai Zhou chemical technology Co., Ltd and is named as Calm Young; the Cladosiphon okamuranus extract is purchased from Shanghai Xigan industries, Ltd; CP05 is a composition of tropolone, caprylhydroxamic acid, and ethylhexylglycerin, available from Shanghai Korea.

Emulsifier

The emulsifier contains hydrophilic group and lipophilic group in its molecule, and can regulate surface tension of each phase in the cosmetic, so that multiple phases can be uniformly dispersed and have stable properties.

In some preferred embodiments, the emulsifier is selected from a mixture of one or more of potassium cetyl phosphate, polyglycerol-3 cocoate, stearate, glyceryl stearate, cetyl stearyl alcohol; further preferably, the emulsifier is potassium cetyl phosphate and/or polyglycerol-3 cocoate; furthermore, the emulsifier is potassium cetyl phosphate and polyglycerol-3 cocoate, and the weight ratio of the potassium cetyl phosphate to the polyglycerol-3 cocoate is 1: (1-2); most preferably, the emulsifier is potassium cetyl phosphate and polyglycerol-3 cocoate, and the weight ratio of potassium cetyl phosphate to polyglycerol-3 cocoate is 1: 1.5.

potassium cetyl phosphate (CAS number 17026-85-6) in the present application was purchased from Shanghai Li Kogyo Co., Ltd; polyglycerol-3 cocoate was purchased from shanghai yohima chemical limited.

Thickening agent

The thickener, also called gelling agent, is a water-soluble high molecular compound, and can form a three-dimensional cross-linked network structure in water, thereby increasing the viscosity and stability of the cosmetic.

In some preferred embodiments, the thickener is selected from a mixture of one or more of EG, xanthan gum, carbomer, polyvinyl alcohol, gelatin, carrageenan; further preferably, the thickener is EG.

EG in this application is a composition of sodium acrylate/sodium acryloyldimethyl taurate copolymer, polyisobutylene, octyl/decyl glucoside, available from Shanghai Saifu chemical engineering development Co.

Auxiliary agent

The auxiliary agent is used for improving the high and low temperature stability of the whitening composition.

In some preferred embodiments, the auxiliary agent is selected from one or more of sodium carboxymethyl cellulose, hydroxyethyl cellulose, methyl cellulose; further preferably, the auxiliary agent is hydroxyethyl cellulose.

Hydroxyethyl cellulose (CAS number 9004-62-0) in this application is available from Shanghai Bo Xue industries, Inc.

In some preferred embodiments, the titanium dioxide has a particle size of 400 nm. Titanium dioxide in this application is purchased from Shanghai Caprico New Material science and technology, Inc.

The multi-effect whitening composition comprises 0.05-0.2 parts of essence by weight, wherein the essence is not particularly limited and can be sold in the market, and the essence is purchased from Shanghai color Union international trade company.

According to the whitening composition, the whitening composition is added with titanium dioxide to play a role in concealing and whitening, but the titanium dioxide has larger surface energy and is difficult to stably disperse in a system, so that the content of the titanium dioxide in the composition is limited. After the mixture of potassium cetyl phosphate and polyglycerol-3 cocoate is added, the dispersion of high-content titanium dioxide is improved through the double effects of electrostatic repulsion and long-chain group steric hindrance. The applicant has found that, surprisingly, when the ratio in parts by weight of potassium cetyl phosphate to polyglycerol-3 cocoate is 1: (1-2), the water-retaining effect of the whitening composition can be improved, possibly due to: cetyl phosphate potassium and polyglycerol-3 coconut oil fatty acid ester form bilayer structure, and hydrophobic carbon chain is inside the bilayer, and hydrophilic group is located the surface of bilayer, because the structure of multilayer parcel, water is wrapped up in this structure, is difficult for evaporating. When the weight part ratio of the potassium cetyl phosphate to the polyglycerol-3 cocoate is more than 1: 1 or less than 1: 2, the balance of the original system is broken, and a regular double-layer structure is difficult to form, so that the water retention effect is reduced.

In some preferred embodiments, the sum of the parts by weight of butylene glycol, glycerin and panthenol in the moisturizer is 1 to 5 times the sum of the parts by weight of potassium cetyl phosphate and polyglycerin-3 coconut oil acid; further preferably, the sum of the parts by weight of butanediol, glycerol and panthenol in the moisturizer is 3 times of the sum of the parts by weight of potassium cetyl phosphate and polyglycerol-3-cocoic acid.

The composition of the invention is added with butanediol, glycerin and panthenol to absorb moisture in the air, so that the skin is maintained in a balanced state with the water content higher than the normal water content, and the effect is cooperated with the water retention effect formed by potassium cetyl phosphate and polyglycerol-3 cocoate to give lasting tenderness and brightness to the skin. The applicant has also found that the stability of the whitening composition can be improved when the sum of the parts by weight of butylene glycol, glycerin, panthenol is 1 to 5 times the sum of the parts by weight of potassium cetyl phosphate and polyglycerin-3 coconut oil acid. Presumably, a certain amount of butanediol, glycerol and panthenol changes the surface tension of water, enhances the affinity of the emulsifier in water, and is beneficial to improving the dispersion degree of potassium cetyl phosphate and polyglycerol-3 cocoate in water, so that the latex particles become small and are uniformly distributed. When the sum of the parts by weight of the butanediol, the glycerol and the panthenol is more than 5 times of the sum of the parts by weight of the potassium cetyl phosphate and the polyglycerol-3 coconut oil acid, the butanediol, the glycerol, the panthenol and the like form a hydration group with water through hydrogen bonds to enter a double-layer structure, and the stability of the structure is damaged.

In some preferred embodiments, the sum of the parts by weight of the potassium cetyl phosphate and the polyglycerol-3-cocoic acid is 1 to 4 times that of the hydroxyethyl cellulose; further preferably, the sum of the parts by weight of the potassium cetyl phosphate and the polyglycerol-3-cocoic acid is 2.5 times of the hydroxyethyl cellulose.

The hydroxyethyl cellulose is added in the whitening composition, and the hydroxyethyl cellulose and the potassium cetyl phosphate and the polyglycerol-3 cocoate form a water retention effect which is mutually synergistic, so that the stability of the whitening composition in the cold and hot storage process is improved, and the phenomena of coarseness, delamination and the like are avoided. The possible reason is that the hydroxyethyl cellulose in the auxiliary agent is cooperated with active groups on the thickening agent, the potassium cetyl phosphate and the polyglycerol-3 cocoate to form a rheological barrier in the emulsion, the rheological barrier can limit the particle size of the emulsion and can also improve the adsorption force between the emollient and the emulsifier, the humectant and other components in the system, when the temperature and other conditions of the system are changed, the multi-layer structure around oil drops weakens the van der Waals force among the oil drops, prevents agglomeration to cause the problems of coarsening, layering and the like, thereby obviously improving the stability of the emollient. When the sum of the parts by weight of the potassium cetyl phosphate and the polyglycerin-3 coconut oil acid and the part by weight of the hydroxyethyl cellulose are less than 1 or more than 4 times, the formation of a uniform system is not facilitated or the particle size is larger in the preparation process.

Examples

The technical solution of the present invention is described in detail by the following examples, but the scope of the present invention is not limited to the examples. The starting materials used in this application are commercially available unless otherwise specified.

Example 1

Embodiment 1 provides a multi-effect whitening composition, which comprises the following components in parts by weight: 57 parts of water, 5 parts of butanediol, 3 parts of glycerol, 1 part of panthenol, 0.03 part of sodium hyaluronate, 0.5 part of hydrolyzed glycosaminoglycans, 5 parts of isononyl isononanoate, 8 parts of polydimethylsiloxane, 1 part of cyclopenta dimethyl siloxane, 1 part of cyclohexasiloxane, 3 parts of octyl dimethyl siloxane, 1 part of plant composite anti-allergic agent, 0.5 part of Cladosiphon starfish extract, 0.4 part of CP05, 6 parts of titanium dioxide, 1.2 parts of potassium cetyl phosphate, 1.8 parts of polyglycerol-3 cocoate, 3.5 parts of thickening agent EG, 1.2 parts of hydroxyethyl cellulose and 0.1 part of rose essence.

The particle size of the titanium dioxide is 400 nanometers.

The plant composite anti-allergic agent is purchased from Shanghai Zhou chemical technology Co., Ltd and is named as Calm Young; the CP05 was purchased from Shanghai Proc.Kogyo Co.Ltd; the thickener EG was purchased from shanghai seifof chemical development ltd.

The preparation method of the multi-effect whitening composition comprises the following steps:

a. adding predispersed butanediol, glycerol, panthenol, sodium hyaluronate, hydrolyzed glycosaminoglycans and hydroxyethyl cellulose into a preparation pot 1 containing water, stirring and heating to 80 ℃ to be uniform;

b. sequentially adding potassium cetyl phosphate, polyglycerol-3 cocoate, isononyl isononanoate, polydimethylsiloxane, cyclopentadimethylsiloxane, cyclohexasiloxane, octylpolydimethylsiloxane and titanium dioxide into a preparation pot 2, stirring and adding to 80 ℃ to be uniform;

c. b, adding a thickening agent EG into the preparation pot 1 in the step a, stirring for 7 minutes, adding the mixed liquid obtained in the step b into the preparation pot 1, stirring for 7 minutes, and cooling;

d. and c, cooling to 40 ℃, adding the plant composite anti-allergic agent, the Cladosiphon okamuranus Dunn extract, CP05 and the rose essence into the mixture obtained in the step c, stirring uniformly, taking materials, detecting, and directly discharging after the materials are qualified.

Example 2

Example 2 provides a multi-effect whitening composition, which is different from example 1 in that the weight part of polyglycerol-3 cocoate in the composition is 1.2 parts.

The present example also provides a method for preparing a multi-effect whitening composition, which has the steps similar to those of example 1.

Example 3

Example 3 provides a multi-effect whitening composition, which is different from example 1 in that the weight part of polyglycerol-3 cocoate in the composition is 2.4 parts.

Example 4

Example 4 provides a multi-effect whitening composition, which is different from example 1 in that the weight part of polyglycerol-3 cocoate in the composition is 0.8 part.

Example 5

Example 5 provides a multi-effect whitening composition, which is different from example 1 in that the weight part of polyglycerol-3 cocoate in the composition is 2.8 parts.

Example 6

Example 6 provides a multi-effect whitening composition, which is different from example 1 in that the composition includes 1 part by weight of butylene glycol, 1 part by weight of glycerin, and 1 part by weight of panthenol.

Example 7

Example 7 provides a multi-effect whitening composition, which is different from example 1 in that the composition includes 7 parts by weight of butylene glycol, 5 parts by weight of glycerin, and 3 parts by weight of panthenol.

Example 8

Example 8 provides a multi-effect whitening composition, which is different from example 1 in that the components include 0.8 part by weight of butylene glycol, 0.8 part by weight of glycerin, and 0.8 part by weight of panthenol.

Example 9

Example 9 provides a multi-effect whitening composition, which is different from example 1 in that the components include 7.5 parts by weight of butylene glycol, 5.5 parts by weight of glycerin, and 3.5 parts by weight of panthenol.

Example 10

Example 10 provides a multi-effect whitening composition, which is different from example 1 in that the weight part of hydroxyethyl cellulose in the composition is 3 parts.

Example 11

Example 11 provides a multi-effect whitening composition, which is different from example 1 in that the weight part of hydroxyethyl cellulose in the components is 0.75 part.

Example 12

Example 12 provides a multi-effect whitening composition, which is different from example 1 in that the weight part of hydroxyethyl cellulose in the components is 3.5 parts.

Example 13

Example 13 provides a multi-effect whitening composition, which is different from example 1 in that the weight part of hydroxyethyl cellulose in the components is 0.7 part.

Example 14

Example 14 provides a multi-effect whitening composition, which is different from example 1 in that polyglycerin-3 cocoate in the composition is replaced with stearate.

Example 15

Example 15 provides a multi-effect whitening composition, which is different from example 1 in that polyglycerin-3 coconut oleate in the composition is replaced with glyceryl stearate.

Example 16

Example 16 provides a multi-effect whitening composition, which is different from example 1 in that potassium cetyl phosphate in the composition is replaced with cetearyl alcohol (CAS No. 67762-27-0).

Example 17

Example 17 provides a multi-effect whitening composition, which is different from example 1 in that polyglycerol-3 cocoate is not included in the composition, and the weight part of potassium cetyl phosphate is 3 parts.

Example 18

Example 18 provides a multi-effect whitening composition, which is different from example 1 in that potassium cetyl phosphate is not included in the composition, and the weight part of polyglycerol-3 cocoate is 3 parts.

Example 19

Example 19 provides a multi-effect whitening composition, which is different from example 1 in that hydroxyethyl cellulose is not included in the composition.

Example 20

Example 20 provides a multi-effect whitening composition, which is different from example 1 in that hydroxyethyl cellulose in the composition is replaced with hypromellose (CAS No. 9004-65-3).

Evaluation of Performance

The multi-effect whitening compositions obtained in examples 1 to 20 were subjected to water retention effect, particle size, and high and low temperature stability tests.

The test method comprises the following steps:

1. water retention effect

A weighing method is adopted, the temperature is set to be 37 ℃, the humidity is RH 60%, 5.00g of sample is accurately weighed, and the sample is uniformly coated on a glass culture dish and placed in a constant temperature and humidity box. The samples were left for 4 and 8 hours, and then weighed to calculate the water retention, and the test results are shown in Table 1.

Water retention (%) - (M)₂/M₁) X 100, wherein M₁For the weight of water before standing, M₂Is the water weight after standing.

2. Particle size

The macroscopic particle size of the samples was measured using a model BETTERSIZE 2000B laser particle size analyzer and the results are shown in table 1.

3. High and Low temperature stability test

High-temperature stability: placing the sample in a 40 ℃ heat preservation box, keeping the temperature for 24 hours, observing the sample after the temperature is recovered to the room temperature, wherein the oil-free water separation condition is qualified, and the test result is shown in table 1;

low-temperature stability: the sample is placed in a refrigerator with the temperature of-8 ℃ for 24 hours, the sample is observed after the room temperature is recovered, the oil-free water separation condition is qualified, and the test result is shown in table 1.

TABLE 1

As can be understood from comparative examples 1 to 20, the synergistic effect among the humectant, the emulsifier and the auxiliary agent increases the stability of the multi-effect whitening composition provided by the invention, and further improves the water retention and other properties, such as whitening and antioxidation, of the multi-effect whitening composition; due to the use of the titanium dioxide, the whitening composition can be immediately whitened after being used, and under the condition of good stability, the whitening composition can be used for a long time, so that the skin brightness is effectively improved, and the synthesis speed of melanin is slowed down.

Finally, it should be understood that the above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The multi-effect whitening composition is characterized by at least comprising the following components in parts by weight: 30-60 parts of water, 9.53 parts of a humectant, 12-20 parts of an emollient, 0.5-3 parts of a skin conditioner, 3-10 parts of titanium dioxide, 3 parts or 2.4 parts or 3.6 parts of an emulsifier, 1-5 parts of a thickener and 1.2 parts of an auxiliary agent, wherein the emulsifier is 1.2 parts of potassium cetyl phosphate and 1.8 parts or 1.2 parts or 2.4 parts of polyglycerol-3 cocoate, the auxiliary agent is hydroxyethyl cellulose, the humectant is a mixture of butanediol, glycerol, panthenol, sodium hyaluronate and hydrolyzed glycosaminoglycans, and the auxiliary agent comprises 5 parts of butanediol, 3 parts of glycerol, 1 part of panthenol, 0.03 part of sodium hyaluronate and 0.5 part of hydrolyzed glycosaminoglycans.

2. The multi-effect whitening composition of claim 1, wherein the emollient is selected from the group consisting of isononyl isononanoate, dimethicone, cyclopentadimethicone, cyclohexasiloxane, octyldimethicone, bis-PEG-18 methyl ether dimethylsilane, cetyl PEG/PPG-10/1 dimethicone, and a mixture of one or more of PEG-12 dimethicone.

3. The multi-effect whitening composition of claim 1, wherein the skin conditioning agent is selected from one or more of a phytocomplex anti-allergy agent, Cladosiphon stardanum extract, CP 05.

4. The multi-effect whitening composition of claim 3, wherein the phytocomplex anti-sensitization agent is a composition consisting of butylene glycol, water, centella asiatica extract, polygonum cuspidatum root extract, scutellaria baicalensis root extract, tea leaf extract, glycyrrhiza glabra root extract, chamomile flower extract, rosemary leaf extract.

5. The multi-effect whitening composition of claim 1, wherein the thickener is selected from the group consisting of one or more of EG, xanthan gum, carbomer, polyvinyl alcohol, gelatin, carrageenan.

6. The multi-effect whitening composition of claim 1, further comprising 0.05 to 0.2 parts by weight of a perfume.

7. The method for preparing the multi-effect whitening composition according to claim 1, comprising the steps of: