CN109998744A - A kind of titanium alloy medicament-release blood vessel stent - Google Patents
A kind of titanium alloy medicament-release blood vessel stent Download PDFInfo
- Publication number
- CN109998744A CN109998744A CN201910276002.6A CN201910276002A CN109998744A CN 109998744 A CN109998744 A CN 109998744A CN 201910276002 A CN201910276002 A CN 201910276002A CN 109998744 A CN109998744 A CN 109998744A
- Authority
- CN
- China
- Prior art keywords
- blood vessel
- bracket
- titanium alloy
- medicament
- liner
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 49
- 210000004204 blood vessel Anatomy 0.000 title claims abstract description 33
- 229910001069 Ti alloy Inorganic materials 0.000 title claims abstract description 24
- 239000012528 membrane Substances 0.000 claims abstract description 16
- 229940079593 drug Drugs 0.000 claims abstract description 11
- 239000000956 alloy Substances 0.000 claims abstract description 5
- 239000000203 mixture Substances 0.000 claims 1
- 238000002651 drug therapy Methods 0.000 abstract description 5
- 208000037803 restenosis Diseases 0.000 abstract description 5
- 230000017531 blood circulation Effects 0.000 abstract description 4
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of titanium alloy medicament-release blood vessel stents, it is related to intravascular stent field, include rack body, rack body is made of bracket outer membrane and bracket inner membrance, bracket outer membrane and bracket inner membrance are made of titanium alloy material, and it is in Openworks shape structure, and is filled with software between bracket outer membrane and bracket inner membrance, outer surface is fixedly connected with outer lug at left and right sides of the bracket outer membrane.The present invention can be by being inflated liner, realize flexible expansion of the outer lug to blood vessel, extent is very extensive, and it adjusts very convenient, it can be adjusted according to the own situation of patient, and after the completion of expansion, internal projection is squeezed by liner, to squeeze medicine ball, it squeezes away it by the drug in medicine ball and enters intravascular, realize that, to the drug therapy of blood vessel, which can not only keep vessel lumen blood flow unobstructed, and the restenosis of blood vessel can also be prevented, it is practical.
Description
Technical field
The present invention relates to intravascular stent field, specifically a kind of titanium alloy medicament-release blood vessel stent.
Background technique
Intravascular stent, which refers to, is placed in inner support in lesion to reach support stenosis occlusion section blood vessel, reduces blood vessel elasticity and returns
Contracting and moulding again, the purpose for keeping lumen blood flow unobstructed, part inner support also have the function of pre- anti-restenosis.
Chinese patent (publication No.: CN107736958A) discloses a kind of titanium alloy medicament-release blood vessel stent, the patent
Including ontology between blood vessel and inner membrance, the rack body is made of titanium alloy, is in hollow tubular structure, and tube wall is in netted knot
Structure, the rack body are set in outside the inner membrance, and the inner membrance includes basal layer and drug-loaded layer, on the one hand inner membrance prevents early stage
On the other hand the formation of thrombus controls the generation of restenosis by treatment preparation, blood vessel is unobstructed after the intervention of common guarantee bracket
Property, furthermore rack body is made of titanium alloy material, and avoid nickel from improving clinical safety to adverse reaction caused by human body,
But the intravascular stent, cannot the support range to rack body be adjusted, degree of support is limited, have certain limitation
Property, the practicability is poor.
Summary of the invention
The purpose of the present invention is to provide a kind of titanium alloy medicament-release blood vessel stents, to solve to mention in above-mentioned background technique
Out the problem of.
To achieve the above object, the invention provides the following technical scheme:
A kind of titanium alloy medicament-release blood vessel stent, including rack body, rack body are made of bracket outer membrane and bracket inner membrance,
Bracket outer membrane and bracket inner membrance are made of titanium alloy material, and are in Openworks shape structure, and bracket outer membrane and bracket inner membrance it
Between be filled with software, outer surface is fixedly connected with outer lug at left and right sides of the bracket outer membrane, and the corresponding other side of outer lug is solid
Surely it is connected with internal projection, internal projection is located at bracket inner membrance inner surface, is equipped with liner inside the bracket inner membrance.
As a further solution of the present invention: being fixedly connected with air inlet pipe above the rack body, air inlet pipe lower end is stretched
Enter to liner inner upper, and be connected and sealed between liner.
As a further solution of the present invention: being fixedly connected with exhaust pipe below the rack body, exhaust pipe upper end is stretched
Enter to liner lower inside, and be connected and sealed between liner.
As a further solution of the present invention: medicine ball is fixedly installed between the outer lug and internal projection, during medicine ball is in
Empty reticular structure.
As a further solution of the present invention: being placed with drug inside the medicine ball.
As further scheme of the invention: the software is in hollow tubular structure.
It compared with prior art, can be by right the beneficial effects of the present invention are: the titanium alloy medicament-release blood vessel stent
Liner is inflated, and realizes flexible expansion of the outer lug to blood vessel, and extent is very extensive, and adjusts unusual side
Just, it can be adjusted according to the own situation of patient, and after the completion of expansion, internal projection is squeezed by liner,
To squeezing medicine ball, make its drug in medicine ball is squeezed go out enter it is intravascular, realization to the drug therapy of blood vessel,
The intravascular stent can not only keep vessel lumen blood flow unobstructed, and can also prevent the restenosis of blood vessel, practical.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of titanium alloy medicament-release blood vessel stent.
Fig. 2 is the cross-sectional view of A-A structure in Fig. 1.
Fig. 3 is what structural schematic diagram in titanium alloy medicament-release blood vessel stent.
In figure: 1- bracket outer membrane, 2- outer lug, 3- bracket inner membrance, 4- liner, 5- software, 6- medicine ball, 7- drug, 8- into
Tracheae, 9- exhaust pipe, 10- internal projection, 11- rack body.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Embodiment one
Please refer to Fig. 1-3, a kind of titanium alloy medicament-release blood vessel stent, including rack body 11, rack body 11 by bracket outside
Film 1 and bracket inner membrance 3 form.
Specifically, the bracket outer membrane 1 and bracket inner membrance 3 are made of titanium alloy material, and are in Openworks shape structure, and
And software 5 is filled between bracket outer membrane 1 and bracket inner membrance 3,1 left and right sides outer surface of bracket outer membrane is fixedly connected with outer
Protrusion 2, the corresponding other side of outer lug 2 is fixedly connected with internal projection 10, and internal projection 10 is located at 3 inner surface of bracket inner membrance, described
Liner 4 is installed inside bracket inner membrance 3, air inlet pipe 8 is fixedly connected with above the rack body 11,8 lower end of air inlet pipe is protruded into
It is connected and sealed to 4 inner upper of liner, and between liner 4, is fixedly connected with exhaust pipe below the rack body 11
9,9 upper end of exhaust pipe extend into 4 lower inside of liner, and is connected and sealed between liner 4.
Furthermore, it is understood that the software 5 is in hollow tubular structure, rack body can be smoothly discharged by being conducive to drug 7
11, to realize the drug therapy to blood vessel.
Embodiment two
Referring to Fig. 1, embodiment two and the difference of embodiment one are, it is fixedly mounted between the outer lug 2 and internal projection 10
There is medicine ball 6, medicine ball 6 is in hollow reticular structure, drug 7 is placed with inside the medicine ball 6, by outer lug 2 and internal projection 10
Between be fixedly installed with medicine ball 6, drug 7 is placed with inside medicine ball 6, when extruding of the medicine ball 6 by liner 4, makes it by medicine ball 6
Interior drug 7 squeezes away, and is discharged to intravascular, drug therapy of the realization to blood vessel.
The titanium alloy medicament-release blood vessel stent can realize outer lug 2 to blood vessel by being inflated to liner 4
Flexibly expand, extent is very extensive, and adjust get up it is very convenient, can be adjusted according to the own situation of patient
Section, and after the completion of expansion, internal projection 10 is squeezed by liner 4, to squeeze medicine ball 6, makes it by medicine
Drug 7 in ball 6, which squeezes away, to be entered intravascular, realizes that, to the drug therapy of blood vessel, which can not only keep blood
Pipe lumen blood flow is unobstructed, and can also prevent the restenosis of blood vessel, practical.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims
Variation is included within the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It will
As a whole, the technical solutions in the various embodiments may also be suitably combined for specification, forms those skilled in the art
The other embodiments that member is understood that.
Claims (6)
1. a kind of titanium alloy medicament-release blood vessel stent, including rack body (11), rack body (11) by bracket outer membrane (1) and
Bracket inner membrance (3) composition, which is characterized in that the bracket outer membrane (1) and bracket inner membrance (3) are made of titanium alloy material, and
Software (5) are filled in Openworks shape structure, and between bracket outer membrane (1) and bracket inner membrance (3), the bracket outer membrane (1) is left
Right two side external surfaces are fixedly connected with outer lug (2), and the corresponding other side of outer lug (2) is fixedly connected with internal projection (10), interior
Raised (10) are located at bracket inner membrance (3) inner surface, are equipped with liner (4) inside the bracket inner membrance (3).
2. titanium alloy medicament-release blood vessel stent according to claim 1, which is characterized in that on the rack body (11)
Side is fixedly connected with air inlet pipe (8), and air inlet pipe (8) lower end extend into liner (4) inner upper, and carries out between liner (4)
It is tightly connected.
3. titanium alloy medicament-release blood vessel stent according to claim 1 or 2, which is characterized in that the rack body
(11) lower section is fixedly connected with exhaust pipe (9), and exhaust pipe (9) upper end extend into liner (4) lower inside, and with liner (4) it
Between be connected and sealed.
4. titanium alloy medicament-release blood vessel stent according to claim 1, which is characterized in that the outer lug (2) and interior
It is fixedly installed with medicine ball (6) between raised (10), medicine ball (6) is in hollow reticular structure.
5. titanium alloy medicament-release blood vessel stent according to claim 4, which is characterized in that put inside the medicine ball (6)
It is equipped with drug (7).
6. titanium alloy medicament-release blood vessel stent according to claim 1, which is characterized in that the software (5) is in hollow
Tubular structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910276002.6A CN109998744B (en) | 2019-04-08 | 2019-04-08 | Titanium alloy drug release intravascular stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910276002.6A CN109998744B (en) | 2019-04-08 | 2019-04-08 | Titanium alloy drug release intravascular stent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109998744A true CN109998744A (en) | 2019-07-12 |
| CN109998744B CN109998744B (en) | 2020-12-22 |
Family
ID=67170240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910276002.6A Expired - Fee Related CN109998744B (en) | 2019-04-08 | 2019-04-08 | Titanium alloy drug release intravascular stent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109998744B (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080243235A1 (en) * | 2007-03-26 | 2008-10-02 | Spielberg Theodore E | Cellular transplant stent |
| CN101695458A (en) * | 2009-10-30 | 2010-04-21 | 南京微创医学科技有限公司 | Biliary tract radiation treatment stent |
| CN101984940A (en) * | 2010-11-03 | 2011-03-16 | 华南理工大学 | Sac-covered esophagus scaffold capable of loading medicaments and preparation method thereof |
| CN102415925A (en) * | 2011-09-15 | 2012-04-18 | 中国人民解放军第三军医大学第一附属医院 | Medical cavity duct stent capable of storing medicines |
| CN102429751A (en) * | 2011-09-15 | 2012-05-02 | 中国人民解放军第三军医大学第一附属医院 | Medical cavity stent with medicament storage cavity |
| US20130073026A1 (en) * | 2011-09-20 | 2013-03-21 | Aga Medical Corporation | Device and method for treating vascular abnormalities |
| CN107744415A (en) * | 2017-11-29 | 2018-03-02 | 成都创客之家科技有限公司 | A kind of titanium alloy carries medicine intravascular stent |
| WO2018199019A1 (en) * | 2017-04-28 | 2018-11-01 | 株式会社パイオラックスメディカルデバイス | Stent |
| CN108771573A (en) * | 2018-06-26 | 2018-11-09 | 柏为（武汉）医疗科技股份有限公司 | It is a kind of can degradable absorption bracket for eluting medicament and its application |
-
2019
- 2019-04-08 CN CN201910276002.6A patent/CN109998744B/en not_active Expired - Fee Related
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080243235A1 (en) * | 2007-03-26 | 2008-10-02 | Spielberg Theodore E | Cellular transplant stent |
| CN101695458A (en) * | 2009-10-30 | 2010-04-21 | 南京微创医学科技有限公司 | Biliary tract radiation treatment stent |
| CN101984940A (en) * | 2010-11-03 | 2011-03-16 | 华南理工大学 | Sac-covered esophagus scaffold capable of loading medicaments and preparation method thereof |
| CN102415925A (en) * | 2011-09-15 | 2012-04-18 | 中国人民解放军第三军医大学第一附属医院 | Medical cavity duct stent capable of storing medicines |
| CN102429751A (en) * | 2011-09-15 | 2012-05-02 | 中国人民解放军第三军医大学第一附属医院 | Medical cavity stent with medicament storage cavity |
| US20130073026A1 (en) * | 2011-09-20 | 2013-03-21 | Aga Medical Corporation | Device and method for treating vascular abnormalities |
| WO2018199019A1 (en) * | 2017-04-28 | 2018-11-01 | 株式会社パイオラックスメディカルデバイス | Stent |
| CN107744415A (en) * | 2017-11-29 | 2018-03-02 | 成都创客之家科技有限公司 | A kind of titanium alloy carries medicine intravascular stent |
| CN108771573A (en) * | 2018-06-26 | 2018-11-09 | 柏为（武汉）医疗科技股份有限公司 | It is a kind of can degradable absorption bracket for eluting medicament and its application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109998744B (en) | 2020-12-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102202721B (en) | Process for generating microwalled encapsulation balloons | |
| US20170014563A1 (en) | Medical Balloon | |
| CN102961200B (en) | With the valve of pulmonary trunk membrane support of anchor mechanism | |
| CN102302820A (en) | Aorta intracavity infusion tube | |
| CN203898496U (en) | Abdominal aorta stent | |
| CN109998744A (en) | A kind of titanium alloy medicament-release blood vessel stent | |
| CN201719412U (en) | Biliary stent with anti-backflow flap | |
| CN204261112U (en) | A kind of hemodialysis blood flow actuator | |
| CN213310619U (en) | Degradable stent with adjustable outer diameter | |
| CN203988521U (en) | A kind of asymmetric conical intravascular stent | |
| CN206167589U (en) | Extracorporal circulatory system is with two -way artery intubate of filling | |
| CN108355225A (en) | A kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows | |
| WO2018019235A1 (en) | Cavopulmonary assisted circulation apparatus | |
| CN215537134U (en) | Descending aorta perfusion tube | |
| CN208448401U (en) | A kind of hemostasis anti-clogging catheter | |
| CN114452033B (en) | Ureteral stent and test device thereof | |
| CN202637196U (en) | Lacrimal passage support with adjustable thickness | |
| CN216571142U (en) | Semi-automatic external gastrointestinal shunt device | |
| CN215914795U (en) | Fish-bubble type nasal stent and medical appliance for prosthesis nose augmentation | |
| CN104324430A (en) | Blood flow adjustor for hematodialysis | |
| CN108703826A (en) | It is a kind of to be molded endovascular stent system at once | |
| CN209253229U (en) | A kind of heart valve bracket and its prosthese | |
| CN208990016U (en) | A kind of hemadostewnosis sacculus dilating catheter without blocking blood flow | |
| CN217448148U (en) | Medicine support suitable for intracranial venous sinus | |
| CN109567980A (en) | A kind of novel vascular stent based on chirality and anti-chiral structure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20201222 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |