CN108355225A - A kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows - Google Patents

A kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows Download PDF

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Publication number
CN108355225A
CN108355225A CN201810067063.7A CN201810067063A CN108355225A CN 108355225 A CN108355225 A CN 108355225A CN 201810067063 A CN201810067063 A CN 201810067063A CN 108355225 A CN108355225 A CN 108355225A
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China
Prior art keywords
valve
backflows
dual anti
preparation
conduit
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CN201810067063.7A
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Chinese (zh)
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CN108355225B (en
Inventor
张海军
段翠海
刘光
李宜玮
王新坤
侯文博
周超
尹玉霞
鲁守涛
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Shandong Branden Medical Devices Co Ltd
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Shandong Branden Medical Devices Co Ltd
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Priority to CN201810067063.7A priority Critical patent/CN108355225B/en
Publication of CN108355225A publication Critical patent/CN108355225A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0009Making of catheters or other medical or surgical tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/24Check- or non-return valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/24Check- or non-return valves
    • A61M2039/2433Valve comprising a resilient or deformable element, e.g. flap valve, deformable disc
    • A61M2039/244Hinged closure member, e.g. flap valve

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The present invention relates to a kind of ductus venosuses and preparation method thereof with the dual anti-valve that backflows, and belong to medical instrument and field of medical materials.The ductus venosus for having the dual anti-valve that backflows is made of conduit and connecting tube, conductor housing end side wall has longitudinal opening, it is designed with high resiliency gasket at connection tube socket, notch is designed on gasket plays the role of second valve, dual valve structure is proximally and distally being formed, dual anti-backflow is played the role of.The valve material therefor is polyurethane, silicon rubber, thermoelastic or other flexible high molecular materials.In vitro, between two valves, and can form positive and negative pressure control system in vivo, the state of conduit, meets different requirements to the ductus venosus of the described dual anti-valve that backflows when preferably adjusting and control infusion, blood drawing, standing.The present invention can be used for inputting chemotherapeutics through vein, can effectively solve the problem of to set the reflux problem during pipe and reduce due to thrombus caused by reflux and plugging, the indwelling catheter time of elongate catheter.

Description

A kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows
Technical field
The invention belongs to medical instruments and field of medical materials, and in particular to a kind of vein with the dual anti-valve that backflows Conduit and preparation method.
Background technology
Intravenous catheter be establish the main method of venous channel, and as chemotherapy, intravenous hyperalimentation treatment, The main instrument of venous access is established in critical patient rescue etc., has been widely used in recent years.For example it is through peripheral venous catheter Pipe is set from periphery venipuncture, catheter tip is located at a kind of deep venouspuncture method of superior vena cava.
Although ductus venosus brings many benefits to patient, after it is placed in human body, it may occur that a variety of related complications, such as Intravenous Infection, phlebothrombosis, conduit fall off or be broken, catheter blockage, mechanical phlebitis etc..And due to blood or drug reflux Caused catheter blockage and thrombus are wherein more serious complication.In order to solve the problems, such as the presence of above-mentioned conduit, the present invention A kind of ductus venosus with the dual anti-valve that backflows is provided, proximally and distally has respectively that there are one valve knots in conduit Structure can more effectively prevent blood reflux and reduce related complication.
United States Patent (USP) US 4671769 discloses a kind of ductus venosus, in catheter wall upper edge central axis joint-cutting, conduit The both sides of joint-cutting are full symmetric, and conduit joint-cutting is in natural enclosing state when not drawing back blood and not defeated, injecting medical liquid.Medical staff Conduit cavity forms negative pressure when drawing back blood, the both sides of conduit joint-cutting indent simultaneously;And when medical staff is transfused liquid, in conduit Chamber forms positive pressure, and joint-cutting convex plays the role of valve.Patent CN 206534923U disclose a kind of warp of counterflow-preventing Peripheral central venous catheter includes mainly that PICC is managed, and connecting seat and extension tube, the patent increase a kind of Y preventing adverse current Type needleless joint is designed with check valve in Y type needleless joints, prevents drug reflux.Patent CN201481988U discloses one kind Medical catheter with multidirectional valve solves blood backflow situation of the conduit in Clinical practice.
Paper " onthe Complications of Phlebitis inthe Patients SubjectedtoInserted PICCand Nursing is analyzed and countermeasure " hair of Tian Qing et al. Table exists《Journal of Nursing Science》, 2006,21 (15) are set pipe complication to three-dimensional valve peripheral central venous catheter in document and are carried out Statistics, setting infections relating after pipe, phlebitis and the complication of returning plugging after blood can exist.The paper of PA Zerla et al. “Open- vs Closed-Tip Valved Peripherally Inserted Central Catheters and Midlines:Findings from a Vascular Access Database " are published in Journal of the Association for Vascular Access, 2015,20(3), ductus venosus of the paper to head end style of opening and valve type It is compared, setting pipe patient to 1341 is counted, the results showed that concurrent caused by the ductus venosus of valve type Disease is less, and the opposite probability for needing tube drawing to reset is also low.
The patent of above-mentioned announcement and the ductus venosus involved in the document delivered are single valve structure, are played anti- It only backflows effect, the present invention relates to a kind of designs of the dual anti-valve that backflows, by separately designing one in catheter proximal end and rear end A valve, in vitro, between two valves, and form positive and negative pressure control system in vivo, preferably adjust and control infusion, take out The state of conduit when blood, standing, to meet different requirements.Especially for pipe is set for a long time, the design of dual valve can subtract Few phenomenon of backflowing at a specified future date, extends indwelling catheter time.
Invention content
The ductus venosus with the dual anti-valve that backflows, has vertical openings in catheter proximal end sidewall design, is open Length is 5-15mm.Separately there are connecting tube, the tube socket medium design of connecting tube to have high resiliency gasket in rear end of conduit.
The high resiliency gasket design has joint-cutting, can be "-" shape joint-cutting, "×" shape joint-cutting or other can have three-dimensional The shape of valve effect.
The thickness of the high resiliency gasket is in 0.5-1.0mm.
The quantity of the joint-cutting is 1-3.
Mainly by tube socket, extension tube, fixed-wing composition after inside of human body sets pipe, is connected described ground connecting tube with connecting tube, Form complete infusion, blood drawing channel.
Described ground tube socket is made of upper bottom nozzle, and centre is high resiliency gasket, and is linked together by fastening type structure.
Described ground conduit, extension tube and high resiliency gasket material therefor are polyurethane, silicon rubber, thermoelastic or other tools Flexible high molecular material.
It can be the medical grade plastics such as makrolon, ABS to connect tube socket and fixed-wing material therefor.
There is the ductus venosus of the dual anti-valve that backflows describedly, in vitro, between two valves, and can be formed in vivo positive and negative Pressure control system, the different requirements of conduit when preferably adjusting and control infusion, blood drawing, standing.
Have the ductus venosus of the dual anti-valve that backflows in addition to suitable for peripheral vein describedly, it may also be used for jugular vein, Central vein, subclavian vein, femoral vein etc. need the field of venous transfusion.
It is a further object of the present invention to provide a kind of methods preparing the above-mentioned ductus venosus with the dual anti-valve that backflows:
Connecting tube is prepared first, and the tube socket of connecting tube is to be molded, and tube socket can be divided into three parts, upper tube socket, bottom nozzle and height Elastomeric pad.Upper tube socket is designed with standard Luer interface, facilitates later stage infusion and tube sealing.Bottom nozzle is connected with extension tube, There is a high resiliency gasket among tube socket, upper bottom nozzle is linked together by physics fastening type structure, and gasket is fixed, and is formed The anti-valve that backflows of first weight.Extension tube is transparent pipe, facilitates observation when infusion and blood drawing.
Then conduit is squeezed out, and conductor housing end seal is closed, wall does vertical-shaped notch in conductor housing end side, forms the valve of the second weight Membrane structure.Conduit is placed in human vas when use, and is connected with connecting tube, infusion, the blood drawing access of completion are formed.
The present invention provides a kind of ductus venosus of dual valve protection, when positive pressure, connects valve at tube socket and inwardly beat It opens, conduit head end valve outwardly opens, and completes infusion;When negative pressure, connects valve at tube socket and outwardly open, conduit head end valve It inwardly opens, completes blood drawing;When indwelling, two valves are turned off, and valve is mainly to prevent air inlet at connection tube socket, the invention Drug reflux can be more efficiently prevented from and blood enters conduit, reduce the incidence of infections relating and thrombus.The design can be into one Step improves the indwelling catheter time of conduit, reduces the occurrence probability for setting pipe infectious-related complication;The activity limitation of patient is further reduced, is carried The quality of life of high patient is horizontal.
Description of the drawings
Fig. 1 is the ductus venosus structural schematic diagram with the dual anti-valve that backflows
Fig. 2 is implantation body conduits' schematic diagram
Fig. 3 is the structural schematic diagram of connecting tube
Fig. 4 is the basic structure schematic diagram for connecting tube socket
Fig. 5 is "-" shape notch gasket schematic diagram
Fig. 6 is "×" shape notch gasket schematic diagram
Fig. 7 is Multiple insion gasket schematic diagram
Wherein:1 conduit;11 vertical joint-cuttings;2 connecting tubes;21 tube sockets;22 extension tubes;23 fixed-wings;24 high resiliency pads Piece;25 gasket joint-cuttings.
Specific implementation mode
In order to make the present invention more obvious and understandable, hereby with preferred embodiment, and attached drawing is coordinated to be described in detail below.It should be understood that These examples are only for illustrating the present invention and are not intended to limit the scope of the present invention.In addition, it should also be understood that, having read the present invention After the content of instruction, those skilled in the art can make various modifications or changes to the present invention, and such equivalent forms are equally fallen In the scope of the appended claims of the present application.
Embodiment 1
Such as Fig. 1, it includes mainly conduit 1, connecting tube 2 to have the ductus venosus of the dual anti-valve that backflows.The conduit 1 it is main Material is silicon rubber.Its conductor housing end side wall is designed with vertical openings 11, and opening length is in 10mm.Connecting tube 2 is mainly by pipe Seat 21, extension tube 22, fixed-wing 23 form, and it is 1 to have " one " shape opening silicone rubber pad 24, quantity in tube socket interior design, silicon The thickness of rubber cushion is 0.5mm.Vertical openings 11 and the silicone rubber pad opening 25 of conduit head end collectively constitutes bivalve film.It will when use Conduit 1 is placed in human vein blood vessel, and is connected with connecting tube 2, forms infusion, the blood drawing access of completion.When positive pressure, connecting tube pipe Valve is inwardly opened at seat, and conduit head end valve outwardly opens, and completes infusion;When negative pressure, connects valve at tube socket and beat outward It opens, conduit head end valve is inwardly opened, and blood drawing is completed;When indwelling, two valves are turned off, connect tube socket at valve mainly to Air inlet is prevented, and head end valve then can prevent drug and blood from entering conduit.
Its specific preparation method is as follows:Connecting tube 2 is prepared first, and the tube socket 21 of connecting tube is to be molded, and tube socket can divide For three parts, upper tube socket, bottom nozzle and high resiliency gasket.Upper tube socket is designed with standard Luer interface, and the later stage is facilitated to be infused and seal Pipe.Bottom nozzle is connected with extension tube 22, has a silica gel pad, upper bottom nozzle to connect by physics fastening type structure among tube socket It is connected together, and gasket is fixed, form the anti-valve that backflows of the first weight.Extension tube 22 is transparent pipe, facilitates infusion and pumping Observation when blood.
Then conduit 1 is squeezed out, and conductor housing end seal is closed, wall does vertical-shaped notch 11 in conductor housing end side, forms the second weight Valve structure.Conduit is placed in human vas when use, and is connected with connecting tube, complete infusion, blood drawing access are formed.
Embodiment 2
The basic structure and application method of product are similar to embodiment 1, except that silicagel pad opening shape is "×" shape, silicon The thickness of rubber cushion is 1.0mm, as shown in Figure 6.
Embodiment 3
The basic structure and application method of product are similar to embodiment 1, except that the quantity of silicagel pad "-" shape opening is 3 It is a, as shown in Figure 7.
Embodiment 4
The basic structure and application method of product are similar to embodiment 1, except that the material of conduit 1 is polyurethane, it is high-elastic Property gasket material be silicon rubber.
Embodiment 5
The basic structure and application method of product are similar to embodiment 1, except that the material of conduit 1 is polyurethane, it is high-elastic Property gasket material be polyurethane.
Embodiment 6
The basic structure and application method of product are similar to embodiment 1, except that the material of conduit 1 is silicon rubber, it is high-elastic Property gasket material be polyurethane.

Claims (10)

1. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows, it is characterised in that product is by conduit and connection Pipe forms, and conductor housing end side wall has vertical openings, connects and is designed with high resiliency gasket at tube socket, there is second on proximal shim A valve in vitro, between two valves, and can form positive and negative pressure control system in vivo, preferably adjust and control infusion, take out The different requirements of conduit when blood, standing.
2. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows according to claim 1, feature It is, the vertical openings length of the conductor housing end side wall is 5-15mm.
3. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows according to claim 1, feature It is, the connecting tube is mainly made of tube socket, extension tube and fixed-wing.
4. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows according to claim 1, feature It is, the high resiliency gasket opening of the connection tube socket is "-" shape or "×" shape or other can have the shape that valve acts on Shape.
5. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows according to claim 1, feature It is, the high resiliency gasket open amount is 1-3, thickness 0.5-1.0mm.
6. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows according to claim 1, feature Be, the material of the conduit, connecting tube and high resiliency gasket be polyurethane, silicon rubber, thermoelastic or other with bullet The high molecular material of property.
7. a kind of ductus venosus and its preparation with the dual anti-valve that backflows according to claim 1 or claim 3 Method, it is characterised in that the material of connection tube socket and fixed-wing is makrolon, ABS or other medical grade plastics.
8. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows according to claim 1, feature It is the conduit in addition to suitable for peripheral vein, it may also be used for the needs such as jugular vein, central vein, subclavian vein, femoral vein The field of venous transfusion.
9. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows according to claim 1, feature It is, the tube socket of connecting tube is to be molded, and tube socket can be divided into three parts, upper tube socket, bottom nozzle and high resiliency gasket;Upper tube socket It is designed with standard Luer interface, bottom nozzle is connected with extension tube, has a high resiliency gasket, upper bottom nozzle to pass through among tube socket Physics fastening type structure links together, and gasket is fixed, and forms the anti-valve that backflows of the first weight.
10. a kind of ductus venosus and preparation method thereof with the dual anti-valve that backflows according to claim 1, feature It is after squeezing out conduit, conductor housing end seal is closed, wall does vertical-shaped notch valve structure in conductor housing end side.
CN201810067063.7A 2018-01-24 2018-01-24 Venous catheter with double anti-backflow valves and preparation method thereof Active CN108355225B (en)

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CN108355225B CN108355225B (en) 2021-04-27

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110947092A (en) * 2019-10-22 2020-04-03 浙江省北大信息技术高等研究院 One-way valve and medical catheter with same
CN112316293A (en) * 2020-11-20 2021-02-05 焦作市人民医院 Anti-reflux combinable extension pipe
CN116495143A (en) * 2023-03-23 2023-07-28 南京工程学院 Underwater sea cucumber catching robot with overall structure and bionic design

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2880135Y (en) * 2006-01-26 2007-03-21 青岛大学医学院附属医院 Tube wall opening type venosus catheter
CN200960351Y (en) * 2006-05-25 2007-10-17 株式会社榎本 Indwelling needle capable of preventing counter-flow effectively
CN102548604A (en) * 2009-10-01 2012-07-04 B.布劳恩梅尔松根股份公司 Catheter insertion device
CN202844313U (en) * 2011-10-06 2013-04-03 贝克顿·迪金森公司 Actuator accessory and conduit assembly system
CN203829454U (en) * 2014-03-24 2014-09-17 中山市贝尔格介入医械有限公司 Peripherally Inserted Central Catheter (PICC) with pressure double-leaf and double-action door

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2880135Y (en) * 2006-01-26 2007-03-21 青岛大学医学院附属医院 Tube wall opening type venosus catheter
CN200960351Y (en) * 2006-05-25 2007-10-17 株式会社榎本 Indwelling needle capable of preventing counter-flow effectively
CN102548604A (en) * 2009-10-01 2012-07-04 B.布劳恩梅尔松根股份公司 Catheter insertion device
CN202844313U (en) * 2011-10-06 2013-04-03 贝克顿·迪金森公司 Actuator accessory and conduit assembly system
CN203829454U (en) * 2014-03-24 2014-09-17 中山市贝尔格介入医械有限公司 Peripherally Inserted Central Catheter (PICC) with pressure double-leaf and double-action door

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110947092A (en) * 2019-10-22 2020-04-03 浙江省北大信息技术高等研究院 One-way valve and medical catheter with same
CN112316293A (en) * 2020-11-20 2021-02-05 焦作市人民医院 Anti-reflux combinable extension pipe
CN112316293B (en) * 2020-11-20 2022-05-31 焦作市人民医院 Anti-reflux combinable extension pipe
CN116495143A (en) * 2023-03-23 2023-07-28 南京工程学院 Underwater sea cucumber catching robot with overall structure and bionic design
CN116495143B (en) * 2023-03-23 2023-11-03 南京工程学院 Underwater sea cucumber catching robot with overall structure and bionic design

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