CN109998744B

CN109998744B - Titanium alloy drug release intravascular stent

Info

Publication number: CN109998744B
Application number: CN201910276002.6A
Authority: CN
Inventors: 姜涛; 吴世锋; 金立方
Original assignee: China-Japan Union Hospital of Jilin University
Current assignee: China-Japan Union Hospital of Jilin University
Priority date: 2019-04-08
Filing date: 2019-04-08
Publication date: 2020-12-22
Anticipated expiration: 2039-04-08
Also published as: CN109998744A

Abstract

The invention discloses a titanium alloy drug release intravascular stent, which relates to the field of intravascular stents and comprises a stent body, wherein the stent body consists of a stent outer membrane and a stent inner membrane, the stent outer membrane and the stent inner membrane are made of titanium alloy materials and are in hollow structures, soft bodies are filled between the stent outer membrane and the stent inner membrane, and outer bulges are fixedly connected to the outer surfaces of the left side and the right side of the stent outer membrane. The invention can realize the flexible expansion of the blood vessel by the outer bulge by inflating the inner container, has very wide expansion range and very convenient adjustment, can be adjusted according to the self condition of a patient, and can extrude the inner bulge by the inner container after the expansion is finished, thereby extruding the medicine ball, extruding the medicine in the medicine ball out to enter the blood vessel, and realizing the medicine treatment of the blood vessel.

Description

Titanium alloy drug release intravascular stent

Technical Field

The invention relates to the field of intravascular stents, in particular to a titanium alloy drug release intravascular stent.

Background

The blood vessel stent is characterized in that an inner stent is placed in a lesion section to achieve the purposes of supporting a blood vessel of a stenotic occlusion section, reducing the elastic retraction and the reshaping of the blood vessel and keeping the blood flow of a lumen smooth, and part of the inner stent also has the effect of preventing restenosis.

Chinese patent (publication No. CN107736958A) discloses a titanium alloy drug release blood vessel stent, and this patent includes body and inner membrance between the blood vessel, the stent body is made by titanium alloy, is the hollow tubular structure, and the pipe wall is network structure, the stent body suit in outside the inner membrance, the inner membrance includes stratum basale and medicine carrying layer, and the inner membrance prevents the formation of early thrombus on the one hand, and on the other hand passes through the emergence of therapeutical preparation control restenosis, guarantees the patency of support intervention back blood vessel jointly, and the stent body adopts titanium alloy material to make in addition, avoids the adverse reaction that nickel caused to the human body, improves clinical safety, but this blood vessel stent can not adjust the support range of stent body, and the support degree is limited, has certain limitation, and the practicality is poor.

Disclosure of Invention

The invention aims to provide a titanium alloy drug-releasing intravascular stent to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

the utility model provides a titanium alloy medicine release blood vessel support, includes the support body, and the support body comprises support adventitia and support intima, and support adventitia and support intima are made by titanium alloy material to be fretwork column structure, and it has the software to fill between support adventitia and the support intima, outside arch of support adventitia left and right sides external surface fixedly connected with, the inside arch of opposite side fixedly connected with that outside arch corresponds, inside arch are located support intima internal surface, support intima internally mounted has the inner bag.

As a further scheme of the invention: the support body top fixedly connected with intake pipe, the inside top of inner bag is stretched into to the intake pipe lower extreme to carry out sealing connection between with the inner bag.

As a further scheme of the invention: the exhaust pipe is fixedly connected to the lower portion of the support body, and the upper end of the exhaust pipe extends into the lower portion of the inner container and is connected with the inner container in a sealing mode.

As a further scheme of the invention: and a medicine ball is fixedly arranged between the outward bulge and the inward bulge and is of a hollow net structure.

As a further scheme of the invention: the medicine is placed in the medicine ball.

As a still further scheme of the invention: the soft body is in a hollow tubular structure.

Compared with the prior art, the invention has the beneficial effects that: this titanium alloy medicine release intravascular stent, can be through aerifing the inner bag, realize outside arch to the nimble expansion of blood vessel, it is very extensive to expand the scope, and adjust unusual convenience, can adjust according to patient's self condition, and after expanding the completion, extrude inside arch through the inner bag, thereby extrude the pill, make its medicine extrusion in with the pill extrude away get into in the blood vessel, realize the medication to blood vessel, this intravascular stent not only can keep the unobstructed blood flow of vascular lumen, and can also prevent vascular restenosis, therefore, the clothes hanger is strong in practicability.

Drawings

Fig. 1 is a structural schematic diagram of a titanium alloy drug-releasing vascular stent.

Fig. 2 is a cross-sectional view of the a-a structure of fig. 1.

Fig. 3 is a schematic structural diagram of what is in the titanium alloy drug-releasing vascular stent.

In the figure: 1-stent outer membrane, 2-outward bulge, 3-stent inner membrane, 4-inner container, 5-soft body, 6-medicine ball, 7-medicine, 8-air inlet pipe, 9-air outlet pipe, 10-inward bulge and 11-stent body.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example one

Referring to fig. 1-3, a titanium alloy drug-releasing stent for blood vessels comprises a stent body 11, wherein the stent body 11 is composed of a stent outer membrane 1 and a stent inner membrane 3.

Specifically, the outer membrane 1 and the inner membrane 3 are made of titanium alloy materials and are of hollow structures, a soft body 5 is filled between the outer membrane 1 and the inner membrane 3, the outer surfaces of the left side and the right side of the outer membrane 1 are fixedly connected with an outward bulge 2, the other side corresponding to the outward bulge 2 is fixedly connected with an inward bulge 10, the inward bulge 10 is located on the inner surface of the inner membrane 3, the inner membrane 3 is internally provided with a liner 4, an air inlet pipe 8 is fixedly connected to the upper portion of the support body 11, the lower end of the air inlet pipe 8 extends into the upper portion of the liner 4 and is in sealing connection with the liner 4, an exhaust pipe 9 is fixedly connected to the lower portion of the support body 11, and the upper end of the exhaust pipe 9 extends into the lower portion of the liner 4 and is in sealing connection with the liner 4.

Furthermore, the soft body 5 is in a hollow tubular structure, which is beneficial to the medicine 7 to be smoothly discharged out of the stent body 11, thereby realizing the medicine treatment of the blood vessel.

Example two

Referring to fig. 1, the difference between the second embodiment and the first embodiment is that a medicine ball 6 is fixedly installed between the outward protrusion 2 and the inward protrusion 10, the medicine ball 6 is of a hollow net structure, a medicine 7 is placed inside the medicine ball 6, the medicine ball 6 is fixedly installed between the outward protrusion 2 and the inward protrusion 10, the medicine 7 is placed inside the medicine ball 6, and when the medicine ball 6 is squeezed by the inner container 4, the medicine 7 in the medicine ball 6 is squeezed out and is discharged into a blood vessel, so that the medicine treatment of the blood vessel is realized.

This titanium alloy medicine release intravascular stent, can inflate through 4 to the inner bag, realize outside arch 2 to the nimble expansion of blood vessel, it is very extensive to expand the scope, and adjust unusual convenience, can adjust according to patient's self condition, and after expanding the completion, extrude inside arch 10 through inner bag 4, thereby extrude pill 6, make it extrude the medicine 7 extrusion of pill 6 in going out and get into in the blood vessel, realize the medication to blood vessel, this intravascular stent not only can keep the blood vessel lumen blood flow unobstructed, but also can prevent vascular restenosis, therefore, the clothes hanger is strong in practicability.

It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.

Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims

1. The utility model provides a titanium alloy medicine release blood vessel support, includes support body (11), and support body (11) comprises support adventitia (1) and support inner membrance (3), its characterized in that, support adventitia (1) and support inner membrance (3) are made by titanium alloy material to be fretwork column structure, support adventitia (1) left and right sides surface fixedly connected with outside arch (2), the inside arch (10) of opposite side fixedly connected with that outside arch (2) correspond, support inner membrance left and right sides internal surface fixedly connected with is inside arch, support inner membrance (3) internally mounted has inner bag (4), support body (11) top fixedly connected with intake pipe (8), intake pipe (8) lower extreme stretches into the inside top of inner bag (4) to with carry out sealing connection between inner bag (4), support body (11) below fixedly connected with blast pipe (9), blast pipe (9) upper end stretches into inside below of inner bag (4) to and carry out sealing connection between inner bag (4), fixed mounting has medicine ball (6) between outside arch (2) and inward arch (10), and medicine ball (6) are hollow network structure, medicine (7) have been placed to medicine ball (6) inside, medicine ball (6) receive inner bag (4) extrusion, medicine (7) in medicine ball (6) get into in the blood vessel.