CN109998102A - A kind of L-carnitine lotus leaf green tea capsule and preparation method thereof - Google Patents
A kind of L-carnitine lotus leaf green tea capsule and preparation method thereof Download PDFInfo
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- CN109998102A CN109998102A CN201910278268.4A CN201910278268A CN109998102A CN 109998102 A CN109998102 A CN 109998102A CN 201910278268 A CN201910278268 A CN 201910278268A CN 109998102 A CN109998102 A CN 109998102A
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- 240000002853 Nelumbo nucifera Species 0.000 title claims abstract description 73
- 235000006508 Nelumbo nucifera Nutrition 0.000 title claims abstract description 73
- 235000006510 Nelumbo pentapetala Nutrition 0.000 title claims abstract description 73
- 239000002775 capsule Substances 0.000 title claims abstract description 40
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title claims abstract description 33
- 244000269722 Thea sinensis Species 0.000 title claims abstract description 21
- 235000009569 green tea Nutrition 0.000 title claims abstract description 19
- QDOXWKRWXJOMAK-UHFFFAOYSA-N dichromium trioxide Chemical compound O=[Cr]O[Cr]=O QDOXWKRWXJOMAK-UHFFFAOYSA-N 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims description 16
- 229920002472 Starch Polymers 0.000 claims abstract description 24
- 239000008107 starch Substances 0.000 claims abstract description 24
- 235000019698 starch Nutrition 0.000 claims abstract description 24
- VHLJDTBGULNCGF-UHFFFAOYSA-N Limonin Natural products CC1(C)OC2CC(=O)OCC23C4CCC5(C)C(CC(=O)C6OC56C4(C)C(=O)CC13)c7cocc7 VHLJDTBGULNCGF-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229940094952 green tea extract Drugs 0.000 claims abstract description 16
- 235000020688 green tea extract Nutrition 0.000 claims abstract description 16
- KBDSLGBFQAGHBE-MSGMIQHVSA-N limonin Chemical compound C=1([C@H]2[C@]3(C)CC[C@H]4[C@@]([C@@]53O[C@@H]5C(=O)O2)(C)C(=O)C[C@@H]2[C@]34COC(=O)C[C@@H]3OC2(C)C)C=COC=1 KBDSLGBFQAGHBE-MSGMIQHVSA-N 0.000 claims abstract description 16
- 239000011812 mixed powder Substances 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 238000002156 mixing Methods 0.000 claims description 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 8
- 239000000945 filler Substances 0.000 claims description 6
- 229910052757 nitrogen Inorganic materials 0.000 claims description 4
- 238000004108 freeze drying Methods 0.000 claims description 3
- 230000006835 compression Effects 0.000 claims description 2
- 238000007906 compression Methods 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims description 2
- 239000012535 impurity Substances 0.000 claims description 2
- 238000007873 sieving Methods 0.000 claims description 2
- RZALONVQKUWRRY-FYZOBXCZSA-N 2,3-dihydroxybutanedioic acid;(3r)-3-hydroxy-4-(trimethylazaniumyl)butanoate Chemical compound OC(=O)C(O)C(O)C(O)=O.C[N+](C)(C)C[C@H](O)CC([O-])=O RZALONVQKUWRRY-FYZOBXCZSA-N 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 14
- 206010012735 Diarrhoea Diseases 0.000 abstract description 5
- 239000000463 material Substances 0.000 abstract description 5
- 206010067484 Adverse reaction Diseases 0.000 abstract description 4
- 206010033557 Palpitations Diseases 0.000 abstract description 4
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 abstract description 4
- 230000006838 adverse reaction Effects 0.000 abstract description 4
- 208000002173 dizziness Diseases 0.000 abstract description 4
- 206010022437 insomnia Diseases 0.000 abstract description 4
- 239000000843 powder Substances 0.000 abstract description 3
- 238000002474 experimental method Methods 0.000 abstract description 2
- 238000011049 filling Methods 0.000 abstract description 2
- 241001465754 Metazoa Species 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 239000012467 final product Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
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- 235000005911 diet Nutrition 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- GADIJPCDIWZEMB-BTNVMJJCSA-N (2r,3r)-2,3-dihydroxybutanedioate;hydron;(3r)-3-hydroxy-4-(trimethylazaniumyl)butanoate Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.C[N+](C)(C)C[C@H](O)CC([O-])=O.C[N+](C)(C)C[C@H](O)CC([O-])=O GADIJPCDIWZEMB-BTNVMJJCSA-N 0.000 description 2
- 208000031226 Hyperlipidaemia Diseases 0.000 description 2
- 230000002354 daily effect Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 150000008442 polyphenolic compounds Chemical class 0.000 description 2
- 235000013824 polyphenols Nutrition 0.000 description 2
- 235000013616 tea Nutrition 0.000 description 2
- BQMPVGMHZKZPBH-BYZBDTJCSA-N (3r)-3-hydroxy-4-(trimethylazaniumyl)butanoate Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O.C[N+](C)(C)C[C@H](O)CC([O-])=O BQMPVGMHZKZPBH-BYZBDTJCSA-N 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 206010033307 Overweight Diseases 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 230000000049 anti-anxiety effect Effects 0.000 description 1
- 239000002249 anxiolytic agent Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 238000002485 combustion reaction Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 244000144993 groups of animals Species 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 229960001518 levocarnitine Drugs 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
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- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
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- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000020989 red meat Nutrition 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000007958 sleep Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of L-carnitine lotus leaf green tea capsule, the raw material containing following parts by weight: 250-270 parts of L-carnitine-L-tartrate, 30-40 parts of Lotus Leafextract, 40-50 parts of green-tea extract, 70-80 parts of lotus nut starch, 3-6 parts of limonin.Experiment proves that reducing the incidence of the adverse reactions such as L-carnitine insomnia, palpitating speed, dizziness, palpitation, diarrhea, and there is better fat-reducing effect.And after addition lotus nut starch, do not need to add other auxiliary materials again, total mixed powder has preferable powder property, meets the filling requirement of capsule.
Description
Technical field
The present invention relates to a kind of L-carnitine lotus leaf green tea capsule and preparation method thereof.
Background technique
With social development, people's living standard increasingly increases, and rhythm of life is also getting faster, the food that people eat at present
Product, locating environment and the factors such as lack exercise, cause many people to be in unhealthy or sub-health state, obesity, hyperlipidemia etc.
Problem occurrence probability is high.
L-carnitine (L-carnitine), also known as l-carnitine are a kind of amino acids for promoting adipose conversion as energy,
Red meat is the main source of L-carnitine.L-carnitine is that one kind is naturally present in the intracorporal amino acid substance of human body,
There is transport fat to mitochondria and accelerate the function of fat combustion and decomposition, so that consumer be allowed to achieve the effect that weight-reducing.
Different types of diet is containing 5-100 milligrams of L-carnitine, but common people can only take in 50 from diet daily
Milligram, vegetarian's intake are less.The main Physiological Function of L-carnitine is to promote adipose conversion at energy, takes L-carnitine energy
Enough while reducing body fat, losing weight, moisture and muscle are not reduced, it is considered to be safer fat-reducing nutrient is mended
Fill product.
As CN201710404140.9 discloses a kind of lotus leaf L-carnitine solid beverage and preparation method thereof.It weighs left-handed
Carnitine tartrate, Lotus Leafextract, sieve with 100 mesh sieve respectively, be uniformly mixed, packaging to get.The present invention can promote adipose conversion
It for the amino acid of energy, has no toxic and side effect to human body, and have effects that clear away heart-fire relieving summer-heat, dissipating stasis and stanching bleeding, disappear wind clearing damp.At present
Also there is product much containing L-carnitine in the market, such as: happy board L-carnitine lotus leaf green tea capsule, primary raw material are a left side to knob again
Carnitine tartrate, Lotus Leafextract, green-tea extract are revolved, addition Lotus Leafextract, green-tea extract increase fat-reducing effect.But
L-carnitine is limited its application in the presence of the side effects such as insomnia, palpitating speed, dizziness, palpitation, diarrhea, malnutrition are caused.
Summary of the invention
It is good that the technical problem to be solved in the present invention is to provide a kind of effects, the L-carnitine diet products of Small side effects.
In order to solve the above technical problems, the invention discloses a kind of L-carnitine lotus leaf green tea capsules, containing following heavy
Measure the raw material of part: 250-270 parts of L-carnitine-L-tartrate, 30-40 parts of Lotus Leafextract, 40-50 parts of green-tea extract, lotus seeds
70-80 parts of powder, 3-6 parts of limonin.
Preferably comprise the raw material of following parts by weight: 260 parts of L-carnitine-L-tartrate, 35 parts of Lotus Leafextract, green tea mention
Take 45 parts of object, 76 parts of lotus nut starch, 4 parts of limonin.
L-carnitine lotus leaf green tea capsule disclosed in this invention, with fat-reducing effect L-carnitine-L-tartrate,
On the basis of Lotus Leafextract, green-tea extract, properly mixed lotus nut starch, limonin are increased, lotus nut starch tonifying spleen and stopping diarrhea,
Kidney-nourishing arresting seminal emission, mental-tranquilization；Limonin, which has to improve, sleeps, the health-care effects such as antianxiety calmness, many components matchings, through testing
Verifying reduces the incidence of the adverse reactions such as L-carnitine insomnia, palpitating speed, dizziness, palpitation, diarrhea, and has more preferable
Fat-reducing effect.And after addition lotus nut starch, not needing to add other auxiliary materials again, total mixed powder has preferable powder property,
Meet the filling requirement of capsule.
The lotus nut starch can be made by the steps: a) lotus seeds, remove impurity, dry；B) preliminary crushing；C) micro mist
Change.Lotus seeds are preferably fresh lotus seed in preparation step a), possess lotus nut, and drying mode is preferably freeze-dried, preparation step c)
Middle micronization mode is preferably air-flow crushing, and air-flow is made of low temperature compression nitrogen, and lotus nut starch silty made from preferred embodiment is thin
Greasy, uniform particle sizes, effect is good.
L-carnitine lotus leaf green tea capsule disclosed in this invention, can be made by the steps: a) each raw material sieving is standby
With；B) L-carnitine-L-tartrate, Lotus Leafextract, green-tea extract, lotus nut starch are weighed according to formula rate to be uniformly mixed, is added
The limonin of formula ratio mixes, and obtains total mixed powder；C) by total mixed-powder with capsule filler fill capsule to get.
Specific embodiment
Above content of the invention is described in further detail again below by way of specific embodiment.But this should not be managed
Solution is limited only to embodiment below for the range of the above-mentioned theme of the present invention.The case where not departing from above-mentioned technical idea of the invention
Under, the various replacements or change made according to ordinary skill knowledge and customary means, should all include in model of the invention
In enclosing.
Embodiment 1
Prescription:
| Material composition | Dosage (kg) |
| L-carnitine-L-tartrate | 25 |
| Lotus Leafextract | 4 |
| Green-tea extract | 5 |
| Lotus nut starch (commercially available) | 8 |
| Limonin | 0.6 |
Preparation method:
1) each raw material sieves with 100 mesh sieve spare；
2) L-carnitine-L-tartrate, Lotus Leafextract, green-tea extract, lotus nut starch mixing are weighed according to formula rate
It is even, the limonin mixing of formula ratio is added, obtains total mixed powder；
3) total mixed-powder is filled into capsule (based on L-carnitine-L-tartrate, 260mg/ capsule) with capsule filler,
To obtain the final product.
Embodiment 2
Prescription:
| Material composition | Dosage (kg) |
| L-carnitine-L-tartrate | 27 |
| Lotus Leafextract | 3 |
| Green-tea extract | 4 |
| Lotus nut starch (self-control) | 7 |
| Limonin | 0.3 |
Lotus nut starch Homemade method:
1) fresh lotus seed possesses lotus nut, freeze-drying；
2) preliminary crushing；
3) 4 DEG C of compressed nitrogen air-flow crushings to get.
Capsule preparation method thereof:
1) each raw material sieves with 100 mesh sieve spare；
2) L-carnitine-L-tartrate, Lotus Leafextract, green-tea extract, lotus nut starch mixing are weighed according to formula rate
It is even, the limonin mixing of formula ratio is added, obtains total mixed powder；
3) total mixed-powder is filled into capsule (based on L-carnitine-L-tartrate, 260mg/ capsule) with capsule filler,
To obtain the final product.
Embodiment 3
Prescription:
Preparation method:.
1) each raw material sieves with 100 mesh sieve spare；
2) L-carnitine-L-tartrate, Lotus Leafextract, green-tea extract, lotus nut starch mixing are weighed according to formula rate
It is even, the limonin mixing of formula ratio is added, obtains total mixed powder；
3) total mixed-powder is filled into capsule (based on L-carnitine-L-tartrate, 260mg/ capsule) with capsule filler,
To obtain the final product.
Embodiment 4
Prescription:
| Material composition | Dosage (kg) |
| L-carnitine-L-tartrate | 26 |
| Lotus Leafextract | 3.5 |
| Green-tea extract | 4.5 |
| Lotus nut starch (self-control) | 7.6 |
| Limonin | 0.4 |
Lotus nut starch Homemade method:
1) fresh lotus seed possesses lotus nut, freeze-drying；
2) preliminary crushing；
3) 4 DEG C of compressed nitrogen air-flow crushings to get.
Capsule preparation method thereof:
1) each raw material sieves with 100 mesh sieve spare；
2) L-carnitine-L-tartrate, Lotus Leafextract, green-tea extract, lotus nut starch mixing are weighed according to formula rate
It is even, the limonin mixing of formula ratio is added, obtains total mixed powder；
3) total mixed-powder is filled into capsule (based on L-carnitine-L-tartrate, 260mg/ capsule) with capsule filler,
To obtain the final product.
Reference examples composition:
Preparation method is the same as embodiment 4.
The measure of merit result of L-carnitine-L-tartrate capsule prepared by above embodiments of the present invention is as follows:
1) it L-carnitine lotus leaf green tea capsule animal experiment: SPF grades male SD rat 110,200~220g of weight, moves
Object adaptable fed 3 days, 11 groups were randomly divided by weight, it is blank control group, hyperlipidemia model control group and Examples 1 to 4 group, right
1~3 group as usual, commercially available 1 (knob again happy board L-carnitine lotus leaf green tea capsule) and commercially available 2 (amendment L-carnitine tea polyphenol tablets),
Blank control group animal is fed with basal feed, and model control group and other test group of animals are fed with high lipid food.It is dynamic to control each group
Object food-intake and amount of drinking water are almost the same, and blank control group and model control group animal drink distilled water, 3 test group of animals drinks
With dissolved gum is intracapsular tolerant or tablet aqueous solution (in terms of L-carnitine-L-tartrate, 30mg/ pcs/day), continue 30 days.Statistics
Weight before and after groups of animals, Examples 1 to 4 group has good control weight effect as the result is shown, and concrete outcome is shown in Table 1:
Table 1
2) it L-carnitine lotus leaf green tea capsule compliance test result: chooses on inspection without organic disease, only exists in overweight state
Female volunteers, the age 35-45 years old, totally 900, all volunteers were fat (body mass index BMI28~32), were randomly divided into
9 groups, Examples 1 to 4, reference examples 1~3, commercially available 1 (knob again happy board L-carnitine lotus leaf green tea capsule) and commercially available 2 are given respectively
(amendment L-carnitine tea polyphenol tablet), take for each person every day L-carnitine product (based on L-carnitine-L-tartrate, 780mg/
It is secondary, twice daily), it is continuous 3 months edible, weight Mean value of index is compared before taking and after taking 3 months, and count adverse reaction
Incidence, the fat-reducing effect of the L-carnitine-L-tartrate capsule of embodiment preparation is good as the result is shown, and insomnia, heartbeat adds
Fastly, the adverse reaction rates such as dizziness, palpitation, diarrhea are substantially reduced, and concrete outcome see the table below: 2:
Table 2
Claims (6)
1. a kind of L-carnitine lotus leaf green tea capsule, which is characterized in that the raw material containing following parts by weight: L-Carnitine tartrate
250-270 parts of salt, 30-40 parts of Lotus Leafextract, 40-50 parts of green-tea extract, 70-80 parts of lotus nut starch, 3-6 parts of limonin.
2. L-carnitine lotus leaf green tea capsule as described in claim 1, which is characterized in that the raw material containing following parts by weight:
260 parts of L-carnitine-L-tartrate, 35 parts of Lotus Leafextract, 45 parts of green-tea extract, 76 parts of lotus nut starch, 4 parts of limonin.
3. L-carnitine lotus leaf green tea capsule as described in claim 1, which is characterized in that the lotus nut starch is as follows
Preparation:
A) lotus seeds remove impurity, dry；
B) preliminary crushing；
C) it is micronized.
4. L-carnitine lotus leaf green tea capsule as claimed in claim 3, which is characterized in that in the lotus nut starch preparation step a)
The lotus seeds are fresh lotus seed, and drying mode is freeze-drying.
5. L-carnitine lotus leaf green tea capsule as claimed in claim 3, which is characterized in that in the lotus nut starch preparation step c)
Micronization mode is air-flow crushing, and air-flow is made of low temperature compression nitrogen.
6. the preparation method of L-carnitine lotus leaf green tea capsule as described in claim 1, which is characterized in that include following step
It is rapid:
A) each raw material sieving for standby；
B) L-carnitine-L-tartrate, Lotus Leafextract, green-tea extract, lotus nut starch are weighed according to formula rate to be uniformly mixed, is added
The limonin mixing for entering formula ratio, obtains total mixed powder；
C) by total mixed-powder with capsule filler fill capsule to get.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910278268.4A CN109998102B (en) | 2019-04-09 | 2019-04-09 | L-carnitine lotus leaf green tea capsule and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910278268.4A CN109998102B (en) | 2019-04-09 | 2019-04-09 | L-carnitine lotus leaf green tea capsule and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109998102A true CN109998102A (en) | 2019-07-12 |
| CN109998102B CN109998102B (en) | 2022-04-29 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102125692A (en) * | 2010-01-13 | 2011-07-20 | 王华明 | Wrapping agent in levo-carnitine wrapping technology and composition of ten series products and preparation method |
| CN108294147A (en) * | 2018-03-30 | 2018-07-20 | 甘肃大整健康管理股份有限公司 | A kind of traditional Chinese medicine health care preparation for fat reducing hypoglycemic |
| CN108904716A (en) * | 2018-07-30 | 2018-11-30 | 吴威 | A kind of fat management composition, preparation method and application |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102125692A (en) * | 2010-01-13 | 2011-07-20 | 王华明 | Wrapping agent in levo-carnitine wrapping technology and composition of ten series products and preparation method |
| CN108294147A (en) * | 2018-03-30 | 2018-07-20 | 甘肃大整健康管理股份有限公司 | A kind of traditional Chinese medicine health care preparation for fat reducing hypoglycemic |
| CN108904716A (en) * | 2018-07-30 | 2018-11-30 | 吴威 | A kind of fat management composition, preparation method and application |
Non-Patent Citations (1)
| Title |
|---|
| 国食健字G20150006: "纽倍乐牌左旋肉碱荷叶绿茶胶囊", 《药最网》 * |
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Address after: 236000 21 Xinhua Road, economic development zone, Yingdong District, Fuyang City, Anhui Province Patentee after: ANHUI QUANKANG PHARMACEUTICAL CO.,LTD. Address before: 236600 West District of Chengguan Town Industrial Park, Taihe County, Fuyang City, Anhui Province Patentee before: ANHUI QUANKANG PHARMACEUTICAL CO.,LTD. |