CN109985193A - A kind of raw tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet - Google Patents
A kind of raw tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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Abstract
The invention discloses a kind of raw tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablets, Golden Larch Bark cortex dictamni traditional Chinese medicine powder is made using the raw tuber of stemona, kuh-seng, alum, Chinese prickly ash, realgar, Fructus meliae toosendan, frutus cnidii, big maple, radix aconiti agrestis, 10 taste Chinese medicine of schizonepeta, the raw materials such as borneol and NaHCO3 are added, it is subject to auxiliary material again to match, the Golden Larch Bark cortex dictamni dispelling wind and arresting itching effervescent tablet of good water solubility is made;The present invention is that have effects that dispelling wind and eliminating dampness, antalgic, dispelling wind and arresting itching, removing toxic substances desinsection and borneol have swelling and pain relieving, clearing heat and detoxicating Chinese medicinal ingredients using raw tuber of stemona kuh-seng traditional Chinese medicine powder;Pharmacological property is reasonably combined, can complement each other, promote drug effect;Especially there is extraordinary therapeutic effect to symptoms such as scabies and pruituses.
Description
Technical field
The present invention relates to the technical field of effervescent tablet, espespecially a kind of raw tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet.
Background technique
Scabies (scabies) system contagion dermatoses as caused by itch mite, are easily propagated in family and collective.It is external
Scabies was just set to become a disease for having the clear cause of disease in 1687.China has found early in the Sui Dynasty.Scabies is mainly itch mite and human body
It infects, can also be propagated by clothes, underwear, towel, female adult can at least survive a couple of days after leaving human body, and incubation period is about closely
It 1 month or so, is also 2 months.The violent itch of skin, it may be possible to which human body is to caused by acquisition sensibility caused by polypide.
Morbidity is apt to occur in wrist and bends side, armpit leading edge, mammary areola, navel week, private parts and femoribus internus mostly since between finger.Child and baby
The variation of scabies Chang Jifa eczema sample, Germ distribution are not true to type, and can be involved head, neck, the palm and toe.Initial skin lesion damage is that the grain of rice is bright red
Color papule, blister, warts and Cuniculus paca.Serious person can occasionally occur together acute nephritis.Skin lesion night surprise is itched, daytime slight itch.
Sarcoptic mite is found at damage to make a definite diagnosis.Local treatment principle is desinsection, antipruritic, handles complication.It falls ill mostly since between finger,
It is apt to occur in wrist and bends side, armpit leading edge, mammary areola, navel week, private parts and femoribus internus.Child and baby's scabies Chang Jifa eczema sample become
Change, Germ distribution is not true to type, and can be involved head, neck, the palm and toe.Scabies is mainly that itch mite is infected closely with human body, can also pass through clothing
Clothes, underwear, towel and propagate, female adult can at least survive a couple of days after leaving human body, incubation period about 1 month or so, also be 2
A month.The violent itch of skin, it may be possible to which human body is to caused by acquisition sensibility caused by polypide.
Although Chinese medicine be obtained by human experimentation in thousands of years as a result, Chinese medicine control scabies can with treating both manifestation and root cause of disease, and
Small side effects;But Chinese medicine is comparatively laborious in use, needs to decoct processing, and needing professional processing technique of Chinese herbs can just make
With bringing many inconvenience to patient;Therefore, how convenient and efficient using Chinese medicine treatment scabies symptom, become vast Chinese medicine
The hot spot that worker pays close attention to always produces effervescent tablet convenient to use, can't hurt stomach and liver etc..
Summary of the invention
A kind of raw tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet of the present invention, using the raw tuber of stemona, kuh-seng, alum, Chinese prickly ash, realgar, river
Raw tuber of stemona kuh-seng traditional Chinese medicine powder is made in chinaberry, frutus cnidii, big maple, radix aconiti agrestis, 10 taste Chinese medicine of schizonepeta, and it is former that borneol and NaHCO3 etc. is added
Material, then be subject to auxiliary material and match, the life tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet of good water solubility is made, realizes quick heat-clearing and damp-drying drug,
The purpose of dispelling wind and arresting itching.
To achieve the goals above, the technical solution of the invention is as follows: a kind of raw tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet
Main material component: raw tuber of stemona kuh-seng traditional Chinese medicine powder 49%~51%, NaH2CO3 40%~42%, borneol 5%~7%.
Auxiliary material component: 0.12 mL/ g ingredient of ethanol solution, Macrogol 6000 2%~4%.
Preparation step:
(1) it extracts: the raw tuber of stemona, kuh-seng, alum, Chinese prickly ash, realgar, Fructus meliae toosendan, frutus cnidii, big maple, radix aconiti agrestis, schizonepeta is removed respectively
Miscellaneous, cleaning, drying, flour mill milling, obtain raw tuber of stemona kuh-seng traditional Chinese medicine powder;
(2) pelletize: using containing 10 % polyvinylpyrrolidones (PVP) 70 % ethanol solutions and raw tuber of stemona kuh-seng traditional Chinese medicine powder,
Borneol, NaHCO3 are mixed into graininess, with 20 and 30 mesh sieves, take between two sieves particle at 50 DEG C forced air drying to water content
< 3%;
(3) it tabletting: takes the particle of above-mentioned drying to be uniformly mixed with Macrogol 6000, enters tabletting machine.
The pharmacological property and effect of the various components of the present invention:
The life tuber of stemona: has the function of the effect of symptoms such as moistening lung to arrest cough, desinsection;
The kuh-seng: there is heat-clearing and damp-drying drug, wind dispelling insecticide;Main damp-heat dysentery, hematochezia, jaundice, difficult urination, oedema,
The effect of leukorrhagia, pruritus vulvae, scabies, leprosy, pruitus, wet poison sore symptom;
The alum: having removing toxic substances desinsection, and eliminating dampness is antipruritic;Antibacterial action, astriction;For dissolving phlegm, eliminating dampness, antidiarrheal, only
Blood, removing toxic substances, desinsection;Epilepsy, sore throat are controlled, remorse saliva is stopped up very, and hepatitis, jaundice, Huang is swollen, taste-blindness rate, and uterine prolapse is white
The effect of band, dysentery, bleeding from five sense organs or subcutaneous tissue, aphthae, sore hemorrhoid scabies, the symptoms such as water, fire, insect bite;
The Chinese prickly ash: having warming spleen and stomach for dispelling cold, dehumidifies, analgesic, desinsection, solution fish raw meat poison;It controls having indigestion to stop drinking, trusted subordinate's crymodynia, vomit,
Oh, the effect of symptoms such as gas of coughing;
The realgar: there is removing toxic substances desinsection, removing dampness and eliminating phlegm, preventing malaria.For carbuncle swells furunculosis, snakebite and bugbite, abdominal pain due to enterositosis is shied
The effect of epilepsy, the symptoms such as malaria;
The Fructus meliae toosendan: there is liver promoting qi circulation and relieving pain of relaxing, expelling parasite;For chest side of body, abdominal distention, colic, abdominal pain due to enterositosis symptom
Effect;
The frutus cnidii: there is warming kidney and enhancing body, eliminating dampness, wind-dispelling, desinsection;For impotence, palace cold, morbid leucorrhoea duye, arthritis with fixed pain caused by dampness pain in the loins;
The effect of controlling eczema of vulva, married woman's pruritus vulvae, trichomonas vaginitis symptom outside;
Big maple: having and dispel pathogenic wind and remove dampness, detoxicating and destroying parasites;Plum sore is cured mainly, the effect of scabies, the symptoms such as the back of the hand chap;
The radix aconiti agrestis: there is dispelling wind and eliminating dampness, antalgic;It is used for treating arthralgia due to cold and dampness, arthralgia, trusted subordinate's crymodynia, cold hernia is had a pain
And the effect of narcotic analgesic symptom;
The schizonepeta: there is wind-dispelling;Inducing diaphoresis;Promoting eruption;Hemostasis;Main cold, fever;Headache;Eye itching;Cough;Abscess of throat;Fiber crops
Rash;Carbuncle swells;Sore scabies;Bleeding from five sense organs or subcutaneous tissue;It spits blood;Hematochezia;Metrorrhagia and metrostaxis;Postpartum anemic fainting.For catching a cold, have a headache, morbilli, rubeola, sore from the beginning of.It fries
Charcoal treating hematochezia, metrorrhagia and metrostaxis, postpartum anemic fainting.Inducing diaphoresis relieve heat, promoting eruption, disappear sore, hemostasis.For catching a cold, measles without adequate eruption, hematochezia collapses
The effect of leakage, nosebleed epistaxis symptom;
The life tuber of stemona kuh-seng traditional Chinese medicine powder be by raw 60 grams of the tuber of stemona, 30 grams of kuh-seng, 30 grams of alum, 15 grams of Chinese prickly ash, 30 grams of realgar,
The 10 taste Chinese medicines such as 30 grams of Fructus meliae toosendan, 30 grams of frutus cnidii, 30 grams of big maple, 10 grams of radix aconiti agrestis, 10 grams of schizonepeta are cleaned respectively, clean, are dried
Dry, flour mill milling must give birth to tuber of stemona kuh-seng traditional Chinese medicine powder after mixing;Have effects that heat-clearing and damp-drying drug, dispelling wind and arresting itching.
The borneol, which has, leads to all keys, dissipates stagnated fire, goes screen improving eyesight, swelling and pain relieving, and heat-clearing dissipates poison dissipates fire removing toxic substances.Control cream
Gland agglomeration, apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm confusing heart, deafness with qi stagnation, sore throat, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen
The effect of film, pinworm disease symptoms.
The CO2 content: NaHCO3 7.5mg/mL amount of water.
As adhesive, this solution usage is about 75% ethanol solution of the selection containing 10 %PVP of the adhesive
0.12 mL/g ingredient.
The selection has lubricity good, and resistance to bond is good, profit of the Macrogol 6000 of good water solubility as effervescent tablet
Lubrication prescription mixes before tabletting with particle, and additive amount is 2%~3%.
The effervescent tablet monolithic agent weighs about 3. 52g, and after being dissolved in 200mL warm water, CO2 is sufficient, has and is easy to transport, protect
Deposit the feature that the phase is long, production is simple, easy to use;And good water solubility, i.e. punching wash, are significant in efficacy, having no toxic side effect, price is low
It is honest and clean.
The present invention gives birth to tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet, if suffering from the patient for the treatment of rheumatic ostealgia, effervescent tablet monolithic is dissolved in
After 200mL warm water 1 time a day, it washes every time 10 minutes, 51 courses for the treatment of, with the apparent clearing heat and detoxicating, desinsection of a course for the treatment of, antipruritic;
The present invention is that have effects that dispelling wind and eliminating dampness, antalgic, dispelling wind and arresting itching, removing toxic substances desinsection and ice using raw tuber of stemona kuh-seng traditional Chinese medicine powder
Piece has swelling and pain relieving, clearing heat and detoxicating Chinese medicinal ingredients;Pharmacological property is reasonably combined, can complement each other, promote drug effect;Especially pair
The symptoms such as scabies and pruitus have extraordinary therapeutic effect.
Specific embodiment
Embodiment 1
(1) main material component: raw tuber of stemona kuh-seng traditional Chinese medicine powder 49%, NaH2CO3 42%, borneol 7%.
Auxiliary material: 0.12 mL/g ingredient of ethanol solution, Macrogol 6000 2%.
(2) technique preparation step:
1) it extracts: the raw tuber of stemona, kuh-seng, alum, Chinese prickly ash, realgar, Fructus meliae toosendan, frutus cnidii, big maple, radix aconiti agrestis, schizonepeta is removed respectively
Miscellaneous, cleaning, drying, extraction obtain raw tuber of stemona kuh-seng traditional Chinese medicine powder;
2) it pelletizes: using 70% ethanol solution and life tuber of stemona kuh-seng traditional Chinese medicine powder, ice containing 10% polyvinylpyrrolidone (PVP)
Piece, NaHCO3 are mixed into graininess, with 20 and 30 mesh sieves, take between two sieves particle at 50 DEG C forced air drying to water content <
3%;
3) it tabletting: takes the particle of above-mentioned drying to be uniformly mixed with Macrogol 6000, enters tabletting machine.
Embodiment 2
(1) main material component: raw tuber of stemona kuh-seng traditional Chinese medicine powder 50%, NaH2CO3 41%, borneol 6%.
Auxiliary material: 0.12 mL/g ingredient of ethanol solution, Macrogol 6000 3%.
(2) technique preparation step:
1) it extracts: the raw tuber of stemona, kuh-seng, alum, Chinese prickly ash, realgar, Fructus meliae toosendan, frutus cnidii, big maple, radix aconiti agrestis, schizonepeta is removed respectively
Miscellaneous, cleaning, drying, extraction obtain raw tuber of stemona kuh-seng traditional Chinese medicine powder;
2) it pelletizes: using 70% ethanol solution and life tuber of stemona kuh-seng traditional Chinese medicine powder, ice containing 10% polyvinylpyrrolidone (PVP)
Piece, NaHCO3 are mixed into graininess, with 20 and 30 mesh sieves, take between two sieves particle at 50 DEG C forced air drying to water content <
3%;
3) it tabletting: takes the particle of above-mentioned drying to be uniformly mixed with Macrogol 6000, enters tabletting machine.
Embodiment 3
(1) main material component: raw tuber of stemona kuh-seng traditional Chinese medicine powder 51%, NaH2CO3 40%, borneol 5%.
Auxiliary material: 0.12 mL/g ingredient of ethanol solution, Macrogol 6000 4%.
(2) technique preparation step:
1) it extracts: the raw tuber of stemona, kuh-seng, alum, Chinese prickly ash, realgar, Fructus meliae toosendan, frutus cnidii, big maple, radix aconiti agrestis, schizonepeta is removed respectively
Miscellaneous, cleaning, drying, extraction obtain raw tuber of stemona kuh-seng traditional Chinese medicine powder;
2) it pelletizes: using 70% ethanol solution and life tuber of stemona kuh-seng traditional Chinese medicine powder, ice containing 10% polyvinylpyrrolidone (PVP)
Piece, NaHCO3 are mixed into graininess, with 20 and 30 mesh sieves, take between two sieves particle at 50 DEG C forced air drying to water content <
3%;
3) it tabletting: takes the particle of above-mentioned drying to be uniformly mixed with Macrogol 6000, enters tabletting machine.
The above, embodiment is only that preferred embodiments of the present invention will be described, not to of the invention
Range is defined, and under the premise of not departing from the spirit of the technology of the present invention, this field engineers and technicians are to skill of the invention
The various changes and improvements that art scheme is made, should fall within the scope of protection determined by the claims of the present invention.
Claims (2)
1. a kind of raw tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet, it is characterized in that: the life tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet
Main material component: raw tuber of stemona kuh-seng traditional Chinese medicine powder 49%~51%, NaH2CO3 40%~42%, borneol 5%~7%;
Auxiliary material component: 0.12 mL/ g ingredient of ethanol solution, Macrogol 6000 2%~4%.
2. a kind of raw tuber of stemona kuh-seng dispelling wind and arresting itching effervescent tablet, it is characterized in that: the life tuber of stemona kuh-seng traditional Chinese medicine powder be by
Raw 60 grams of the tuber of stemona, 30 grams of kuh-seng, 30 grams of alum, 15 grams of Chinese prickly ash, 30 grams of realgar, 30 grams of Fructus meliae toosendan, 30 grams of frutus cnidii, big maple 30
Gram, 10 grams of radix aconiti agrestis, the 10 taste Chinese medicines such as 10 grams of schizonepeta clean, clean, dry respectively, it is bitter must to give birth to the tuber of stemona for flour mill milling after mixing
Join traditional Chinese medicine powder.
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CN116763883A (en) * | 2023-07-26 | 2023-09-19 | 黑龙江中医药大学 | Effervescent tablet lotion containing traditional Chinese medicine extract and preparation method thereof |
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CN116763883A (en) * | 2023-07-26 | 2023-09-19 | 黑龙江中医药大学 | Effervescent tablet lotion containing traditional Chinese medicine extract and preparation method thereof |
CN116763883B (en) * | 2023-07-26 | 2024-04-09 | 黑龙江中医药大学 | Effervescent tablet lotion containing traditional Chinese medicine extract and preparation method thereof |
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Application publication date: 20190709 |