CN109954061A - Rhinitis and nasosinusitis formula and production method - Google Patents
Rhinitis and nasosinusitis formula and production method Download PDFInfo
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- CN109954061A CN109954061A CN201711426717.2A CN201711426717A CN109954061A CN 109954061 A CN109954061 A CN 109954061A CN 201711426717 A CN201711426717 A CN 201711426717A CN 109954061 A CN109954061 A CN 109954061A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention belongs to technical field of traditional Chinese medicine preparation, especially a kind of to treat rhinitis, the pharmaceutical formulation of nasosinusitis and production method.The raw material for making the treatment liquid all uses Chinese herbal medicine, comprising: goose fails to see grass, lemon, Ilex Latifolia Thunb, the tuber of pinellia, mandarin duck tangerine, pawpaw, throatroot；The Chinese herbal medicine for decocting extracting solution is extracted, they include: goose not only grass, Ilex Latifolia Thunb, throatroot, the tuber of pinellia；The Chinese herbal medicine of fresh juice extracting solution is extracted, they include: pawpaw, mandarin duck tangerine, lemon.The production method of the treatment liquid is: by 1~1.5 part of 2~3 parts of the decoction extracting solution that is extracted from the Chinese herbal medicine formed according to the ratio and fresh juice extracting solution after mixing rhinitis and nasosinusitis treat liquid finished product.By rhinitis and nasosinusitis treatment drop intranasal when treatment.The treatment liquid is significant in efficacy, and Small side effects, curative effect is fast, is not required to take orally.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, especially a kind of formula and production for treating rhinitis and nasosinusitis
Method.
Background technique
Rhinitis and nasosinusitis are a kind of common infection of the upper respiratory tract diseases, very big pain are brought to patient, although at present
Rhinitis is treated in the market and the drug of nasosinusitis is numerous, but there is no the specific drug for the treatment of rhinitis and nasosinusitis up to now, it is used
Drug whether all there is many shortcomings, Western medicine can only alleviate rhinitis and nasosinusitis symptom for Chinese medicine or Western medicine, it is secondary
Effect is big, and more senses are dizzy, drowsiness etc. after patient's clothes, and there are also GI irritations for some, or even damage liver, kidney, to old man, small
Child is especially unsuitable；And Chinese medicine works slowly, dosage is big, and curative effect is generally bad, and also has certain side effect.In short, at present still
Without side-effects small, expenses for medicine is low, and treatment, prevention are easy, is not required to the Chinese and Western medicine for the treatment of rhinitis and nasosinusitis for oral administration.
Summary of the invention
The purpose of the present invention is big for side effect present in the existing Western medicine for treating rhinitis and nasosinusitis, Chinese medicine is risen
Effect is slow, dosage is big, curative effect is universal bad and shortcoming that is also having certain side effect, provides a kind of Small side effects, and curative effect is fast,
Expenses for medicine is low, and treatment, prevention are easy, the production method for being not required to the treatment liquid and the treatment liquid for the treatment of rhinitis and nasosinusitis for oral administration.
The technical solution adopted by the present invention is that complete in the following way: the raw material of production rhinitis and nasosinusitis dropping liquid is whole
Using Chinese herbal medicine, they include: that goose fails to see grass, lemon, Ilex Latifolia Thunb, the tuber of pinellia, mandarin duck tangerine, pawpaw, throatroot.It wherein presses from medium-height grass
The substance extracted in medicine is different, and said herbal medicine is divided into two classes, they are respectively:
1, the Chinese herbal medicine for decocting extracting solution is extracted, they include: goose not only grass, Ilex Latifolia Thunb, throatroot, the tuber of pinellia.It is matched (by weight
Meter) goose not only grass: Ilex Latifolia Thunb: throatroot: the tuber of pinellia=4:1~2:0.5~l:0.5~l
2, the Chinese herbal medicine of fresh juice extracting solution is extracted, they include: pawpaw, mandarin duck tangerine, lemon.It matches (by weight): pawpaw:
Mandarin duck tangerine: lemon=l:0.5~1:0.5~1
The production method of invention rhinitis and nasosinusitis treatment liquid is:
L, it is extracted from the Chinese herbal medicine formed according to the ratio and decocts extracting solution: will weighed goose not only grass, Ilex Latifolia Thunb, bigcatkin willow according to the ratio
Plum, the tuber of pinellia are cleaned, after chopping, and 5~15 times of water is added and is decocted 6~12 hours using 100~180 ~ C temperature, after decoction often
Temperature is 2~8 hours cooling, and decoction liquor is centrifuged, and the decoction liquor being centrifuged is concentrated i.e. through high temperature and pressure
The decoction extracting solution from the Chinese herbal medicine formed by said ratio is obtained, wherein cocnentration factor is 5:1.5~2.5.
2, fresh juice extracting solution is extracted from the Chinese herbal medicine formed according to the ratio: will weighed pawpaw, mandarin duck tangerine and lemon according to the ratio
After lemon is cleaned, cuts thigh, squeeze the juice；0.1~3% vinegar is added in the juice squeezed and 0.2~2% carbohydrase is sent out
Ferment is catalyzed 8~72 hours；Juice after fermented catalysis is centrifuged；To the juice being centrifuged, through height
The fresh juice extracting solution from the Chinese herbal medicine formed by said ratio has been obtained after warm sterilization treatment.
3, by 2~3 parts of decoction extracting solution obtained above and fresh juice extracting solution l~1.5 part after mixing rhinitis
Nasosinusitis therapy liquid finished product.
Method using above-mentioned rhinitis and nasosinusitis treatment liquid treatment rhinitis or nasosinusitis is as follows: rhinitis and nasosinusitis is treated liquid
Drop is intranasal, and each dosage control is within 0.02cc.
The present invention has Small side effects compared with the Chinese and Western medicine of existing treatment rhinitis and nasosinusitis, small to human toxicity；
Curative effect is fast, and l~5 minute tell on after general medication: medication saves, and a drug amount is within 0.02cc, treatment, prevention letter
Just, it is not required to feature for oral administration.According to clinical statistics, the effective percentage of rhinitis and nasosinusitis treatment liquid treatment rhinitis and nasosinusitis of the present invention reaches
98%, cure rate is up to 85%.
Specific embodiment
Rhinitis and nasosinusitis dropping liquid of the present invention is described further below by embodiment.
Production rhinitis and nasosinusitis treatment liquid raw material using goose fail to see grass, lemon, Ilex Latifolia Thunb, the tuber of pinellia, mandarin duck tangerine, pawpaw,
Throatroot Chinese herbal medicine.
Wherein different by the substance extracted from Chinese herbal medicine, said herbal medicine is divided into two classes, they are respectively:
1, the Chinese herbal medicine for decocting extracting solution is extracted, they include: goose not only grass, Ilex Latifolia Thunb, throatroot, the tuber of pinellia.It is matched (by weight
Meter) goose not only grass: Ilex Latifolia Thunb: throatroot: the tuber of pinellia=4:1.5:0.5:l
2, the Chinese herbal medicine of fresh juice extracting solution is extracted, they include: pawpaw, mandarin duck tangerine, lemon.It matches (by weight): pawpaw:
Mandarin duck tangerine: lemon=l:0.5:1
The manufacturing process of rhinitis and nasosinusitis treatment liquid is:
L, it is extracted from the Chinese herbal medicine formed according to the ratio and decocts extracting solution: will weighed goose not only grass, Ilex Latifolia Thunb, bigcatkin willow according to the ratio
Plum, the tuber of pinellia are cleaned, after chopping, and 12 times of water is added and is decocted 8 hours using 110 DEG C of temperature, room temperature cooling 4 hours after decoction,
Decoction liquor is centrifuged, the decoction liquor being centrifuged has been obtained matching from by above-mentioned through high temperature and pressure concentration
Than the decoction extracting solution in the Chinese herbal medicine of composition, wherein cocnentration factor is 5:2.
2, fresh juice extracting solution is extracted from the Chinese herbal medicine formed according to the ratio: will weighed pawpaw, mandarin duck tangerine and lemon according to the ratio
Lemon is cleaned, after chopping, is squeezed the juice；1.6% vinegar is added in the juice squeezed and 0.8% carbohydrase carries out fermentation catalysis
8~72 hours；Juice after fermented catalysis is centrifuged；To the juice being centrifuged, through high-temperature sterilization
The fresh juice extracting solution from the Chinese herbal medicine formed by said ratio has been obtained after processing.
3, by 1.2 parts of 2.5 parts of decoction extracting solution obtained above and fresh juice extracting solution after mixing rhinitis nasal sinus
Inflammation treatment liquid finished product.
Claims (2)
1. a kind of rhinitis and nasosinusitis treats liquid, it is characterised in that: the raw material for making rhinitis and nasosinusitis treatment liquid includes: that goose is failed to see
Grass, lemon, Ilex Latifolia Thunb, the tuber of pinellia, mandarin duck tangerine, pawpaw, throatroot, wherein it is different by the substance extracted from Chinese herbal medicine, among the above
Herbal medicine is divided into two classes, they are respectively:
A, the Chinese herbal medicine for decocting extracting solution is extracted, they include: goose not only grass, Ilex Latifolia Thunb, throatroot, the tuber of pinellia;It is matched (by weight
Meter) goose not only grass: Ilex Latifolia Thunb: throatroot: the tuber of pinellia=4:1~2:0.5~l:0.5~l；
B, the Chinese herbal medicine of fresh juice extracting solution is extracted, they include: pawpaw, mandarin duck tangerine, lemon;It matches (by weight): pawpaw:
Mandarin duck tangerine: lemon=l:0.5~1:0.5~1.
2. the production method of rhinitis and nasosinusitis according to claim 1 treatment liquid, it is characterised in that: the production method includes
Following steps:
A, it is extracted from the Chinese herbal medicine formed according to the ratio and decocts extracting solution: will weighed goose not only grass, Ilex Latifolia Thunb, bigcatkin willow according to the ratio
Plum, the tuber of pinellia are cleaned, after chopping, and 5~15 times of water is added and is decocted 6~12 hours using 100~180 ~ C temperature, after decoction often
Temperature is 2~8 hours cooling, and decoction liquor is centrifuged, and the decoction liquor being centrifuged is concentrated i.e. through high temperature and pressure
The decoction extracting solution from the Chinese herbal medicine formed by said ratio is obtained, wherein cocnentration factor is 5:1.5~2.5；
B, fresh juice extracting solution is extracted from the Chinese herbal medicine formed according to the ratio: weighed pawpaw, mandarin duck tangerine and lemon will be passed through according to the ratio
After cleaning, cutting thigh, squeeze the juice；0.1~3% vinegar is added in the juice squeezed and 0.2~2% carbohydrase carries out fermentation and urges
Change 8~72 hours；Juice after fermented catalysis is centrifuged；To the juice being centrifuged, go out through high temperature
The fresh juice extracting solution from the Chinese herbal medicine formed by said ratio has been obtained after bacterium processing；
C, by 2~3 parts of decoction extracting solution obtained above and fresh juice extracting solution l~1.5 part after mixing rhinitis nasal sinus
Inflammation treatment liquid finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711426717.2A CN109954061A (en) | 2017-12-26 | 2017-12-26 | Rhinitis and nasosinusitis formula and production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711426717.2A CN109954061A (en) | 2017-12-26 | 2017-12-26 | Rhinitis and nasosinusitis formula and production method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109954061A true CN109954061A (en) | 2019-07-02 |
Family
ID=67021550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711426717.2A Withdrawn CN109954061A (en) | 2017-12-26 | 2017-12-26 | Rhinitis and nasosinusitis formula and production method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109954061A (en) |
-
2017
- 2017-12-26 CN CN201711426717.2A patent/CN109954061A/en not_active Withdrawn
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| Date | Code | Title | Description |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20190702 |
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| WW01 | Invention patent application withdrawn after publication |