CN109937051A - 治疗tim-3升高的方法 - Google Patents

治疗tim-3升高的方法 Download PDF

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Publication number
CN109937051A
CN109937051A CN201780069200.4A CN201780069200A CN109937051A CN 109937051 A CN109937051 A CN 109937051A CN 201780069200 A CN201780069200 A CN 201780069200A CN 109937051 A CN109937051 A CN 109937051A
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cancer
cells
administered
antibody
therapy
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CN201780069200.4A
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Chinese (zh)
Inventor
E·阿圭勒-科多瓦
B·古兹克
L·K·阿圭勒
A·E·基奥卡
S·劳勒
M·C·斯佩兰扎
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Advantage Cos
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Advantage Cos
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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  • Molecular Biology (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN201780069200.4A 2016-09-26 2017-09-26 治疗tim-3升高的方法 Pending CN109937051A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662399976P 2016-09-26 2016-09-26
US62/399,976 2016-09-26
PCT/US2017/053496 WO2018058123A1 (en) 2016-09-26 2017-09-26 Methods of treating tim-3 elevation

Publications (1)

Publication Number Publication Date
CN109937051A true CN109937051A (zh) 2019-06-25

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Application Number Title Priority Date Filing Date
CN201780069200.4A Pending CN109937051A (zh) 2016-09-26 2017-09-26 治疗tim-3升高的方法

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US (1) US20210369837A1 (https=)
EP (1) EP3515486A4 (https=)
JP (1) JP2019534322A (https=)
KR (1) KR20190059304A (https=)
CN (1) CN109937051A (https=)
CA (1) CA3037253A1 (https=)
IL (1) IL265568A (https=)
MX (1) MX2019003314A (https=)
WO (1) WO2018058123A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109757103B (zh) 2016-07-14 2024-01-02 百时美施贵宝公司 针对tim3的抗体及其用途
AU2020224164A1 (en) * 2019-02-22 2022-02-10 Candel Therapeutics, Inc. GMCI and DDRI combination therapy for treating cancer
EP4037705A4 (en) * 2019-09-30 2024-02-21 Candel Therapeutics, Inc. Combination gmci and atri cancer treatment

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030100527A1 (en) * 1994-07-15 2003-05-29 The University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules for activating dendritic cells
US20060120995A1 (en) * 2004-12-02 2006-06-08 Shah Maulik R Neoadjuvant genetic compositions and methods
CN105828834A (zh) * 2013-11-05 2016-08-03 同源生物服务股份有限公司 检查点抑制剂和治疗剂的组合以治疗癌症
US20160250322A1 (en) * 2015-02-06 2016-09-01 Heat Biologics, Inc. Vector co-expressing vaccine and costimulatory molecules
US20160272707A1 (en) * 2013-09-11 2016-09-22 Compugen Ltd. Vstm5 antibodies, and uses thereof for treatment of cancer, infectious diseases and immune related diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY36391A (es) * 2014-11-05 2016-06-01 Flexus Biosciences Inc Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido1), sus métodos de síntesis y composiciones farmacèuticas que las contienen

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030100527A1 (en) * 1994-07-15 2003-05-29 The University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules for activating dendritic cells
US20060120995A1 (en) * 2004-12-02 2006-06-08 Shah Maulik R Neoadjuvant genetic compositions and methods
US20160272707A1 (en) * 2013-09-11 2016-09-22 Compugen Ltd. Vstm5 antibodies, and uses thereof for treatment of cancer, infectious diseases and immune related diseases
CN105828834A (zh) * 2013-11-05 2016-08-03 同源生物服务股份有限公司 检查点抑制剂和治疗剂的组合以治疗癌症
US20160250322A1 (en) * 2015-02-06 2016-09-01 Heat Biologics, Inc. Vector co-expressing vaccine and costimulatory molecules

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KR20190059304A (ko) 2019-05-30
MX2019003314A (es) 2020-01-30
CA3037253A1 (en) 2018-03-29
EP3515486A4 (en) 2020-05-20
WO2018058123A1 (en) 2018-03-29
EP3515486A1 (en) 2019-07-31
US20210369837A1 (en) 2021-12-02
JP2019534322A (ja) 2019-11-28
IL265568A (en) 2019-05-30

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