CN109923102B - 普利多匹定用于治疗功能下降的用途 - Google Patents

普利多匹定用于治疗功能下降的用途 Download PDF

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Publication number
CN109923102B
CN109923102B CN201780066778.4A CN201780066778A CN109923102B CN 109923102 B CN109923102 B CN 109923102B CN 201780066778 A CN201780066778 A CN 201780066778A CN 109923102 B CN109923102 B CN 109923102B
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twice
pridopidine
day
patient
baseline
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CN109923102A (zh
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迈克尔·海登
史派瑞顿·帕帕佩特罗普洛斯
尤哈-马蒂·萨福拉
伊莱·埃亚勒
贝丝·博罗夫斯基
伊戈尔·D·格拉切夫
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Prenia Medical Development Co ltd
Prenia Neurotherapy Co ltd
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Prenia Medical Development Co ltd
Prenia Neurotherapy Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201780066778.4A 2016-08-24 2017-08-24 普利多匹定用于治疗功能下降的用途 Active CN109923102B (zh)

Priority Applications (1)

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CN202211419342.8A CN115671103A (zh) 2016-08-24 2017-08-24 普利多匹定用于治疗功能下降的用途

Applications Claiming Priority (9)

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US201662379175P 2016-08-24 2016-08-24
US62/379,175 2016-08-24
US201662395263P 2016-09-15 2016-09-15
US62/395,263 2016-09-15
US201662411511P 2016-10-21 2016-10-21
US62/411,511 2016-10-21
US201662416685P 2016-11-02 2016-11-02
US62/416,685 2016-11-02
PCT/US2017/048461 WO2018039477A1 (en) 2016-08-24 2017-08-24 Use of pridopidine for treating functional decline

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CN109923102B true CN109923102B (zh) 2022-11-15

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EP (2) EP3504187B8 (https=)
JP (2) JP6912574B2 (https=)
CN (2) CN109923102B (https=)
AU (2) AU2017315783C1 (https=)
BR (1) BR112019003732A2 (https=)
CA (2) CA3151507C (https=)
CL (2) CL2019000485A1 (https=)
DK (1) DK3504187T3 (https=)
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FI (1) FI3504187T3 (https=)
HU (1) HUE071008T2 (https=)
IL (1) IL311081A (https=)
MX (2) MX390627B (https=)
PL (1) PL3504187T3 (https=)
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JP7436524B2 (ja) * 2019-06-12 2024-02-21 プリレニア ニューロセラピューティクス リミテッド ハンチントン病及びその症状を治療するためのプリドピジン及びその類似体を含む組成物
CN115551505B (zh) * 2020-05-04 2026-03-17 普瑞尼亚神经治疗有限公司 使用选择性s1r激动剂治疗病毒性感染、疾病或病症
WO2022219637A1 (en) * 2021-04-14 2022-10-20 Prilenia Neurotherapeutics Ltd. Treatment of prodromal huntington disease
WO2025164698A1 (ja) * 2024-01-31 2025-08-07 株式会社ケイファーマ ハンチントン病治療剤及び治療用組成物

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EP4516356A3 (en) 2025-05-14
AU2017315783B2 (en) 2020-05-28
EP3504187A4 (en) 2020-05-06
EP3504187A1 (en) 2019-07-03
CN115671103A (zh) 2023-02-03
WO2018039477A1 (en) 2018-03-01
CL2019000485A1 (es) 2019-07-12
PT3504187T (pt) 2025-05-09
JP2019524898A (ja) 2019-09-05
EP4516356A2 (en) 2025-03-05
IL311081A (en) 2024-04-01
AU2017315783C1 (en) 2020-12-24
US11207310B2 (en) 2021-12-28
AU2017315783A1 (en) 2019-04-11
MX2019002265A (es) 2019-10-30
AU2020223736A1 (en) 2020-09-17
CA3151507A1 (en) 2018-03-01
ES3025836T3 (en) 2025-06-09
CN109923102A (zh) 2019-06-21
JP6912574B2 (ja) 2021-08-04
HUE071008T2 (hu) 2025-07-28
EP3504187B1 (en) 2025-02-19
DK3504187T3 (da) 2025-04-14
US20180055832A1 (en) 2018-03-01
CL2019003924A1 (es) 2020-05-29
BR112019003732A2 (pt) 2020-02-18
CA3151507C (en) 2024-05-28
PL3504187T3 (pl) 2025-06-09
EP3504187B8 (en) 2025-03-26
CA3035092A1 (en) 2018-03-01
NZ751156A (en) 2021-01-29
JP2021119186A (ja) 2021-08-12
AU2020223736B2 (en) 2022-04-07
MX2022003072A (es) 2022-06-17
CA3035092C (en) 2022-05-31
MX390627B (es) 2025-03-21
FI3504187T3 (fi) 2025-04-05

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