CN109922853B - 用于cpap装置的鼻接口 - Google Patents

用于cpap装置的鼻接口 Download PDF

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Publication number
CN109922853B
CN109922853B CN201780055191.3A CN201780055191A CN109922853B CN 109922853 B CN109922853 B CN 109922853B CN 201780055191 A CN201780055191 A CN 201780055191A CN 109922853 B CN109922853 B CN 109922853B
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China
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nasal
bud
interface
bellows
sidewall
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CN201780055191.3A
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CN109922853A (zh
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S.A.马什
J.M.奥蒙德
B.R.霍塔林
J.A.麦克内尔
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Encite LLC
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Encite LLC
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Abstract

描述了一种用于被附接到使用者鼻子的装置的鼻接口。所述鼻接口特别适用于CPAP装置,并且包括装置主体以及支撑在该主体上的鼻接口,所述装置主体具有穿过主体的空气通路,该空气通路终止于一对端部部分,每个端部部分在该端部部分的第一表面中具有至少一个出口,所述鼻接口包括一对鼻芽,所述鼻芽在其端部部分处具有扩口配件。

Description

用于CPAP装置的鼻接口
背景技术
本说明书涉及用于治疗呼吸障碍的CPAP装置。
持续气道正压(continuous positive airway pressure)装置(CPAP)装置是一种通过向使用者提供微量气压以保持使用者气道打开来治疗呼吸障碍的装置。CPAP装置通常由具有呼吸障碍、例如睡眠呼吸暂停的人使用。传统上,CPAP机器被使用,并且其包括面罩或装配在使用者的鼻子和/或鼻子和嘴上的其他装置、在被使用者佩戴时将面罩保持在位的带子,和将面罩连接到机器的管道,该机器将空气吹入管道中。
发明内容
根据一个方面,气道压力呼吸装置包括主体,该主体具有穿过主体的一对空气通路,该一对空气通路终止于一对端部部分,每个端部部分在该端部的第一表面中具有至少一个出口;由主体支撑的微型泵,所述微型泵构造成将环境空气通过主体中的空气通路泵送到端部部分;和支撑在主体上的鼻接口,所述鼻接口包括一对鼻芽,所述一对鼻芽在其端部部分处具有扩口配件。
根据一个方面,一种可附接到使用者鼻子的装置包括主体,该主体具有穿过主体的一对空气通路,该一对空气通路终止于一对端部部分,每个端部部分在该端部部分的第一表面中具有至少一个出口;和附接到主体的鼻接口,所述鼻接口包括一对鼻芽,每个鼻芽具有外部台面形侧壁,该侧壁在第一端部处终止于扩口部分并且在第二端部处终止于主体的所述一对空气通路的相应一个。
根据一个方面,用于将装置附接到使用者鼻子的鼻接口包括一对鼻芽,每个鼻芽具有包围通道的侧壁,侧壁的外部形状是台面形的,所述侧壁在一个端部处终止于扩口配件,并且每个所述鼻芽在所述侧壁的第二相对远端端部处具有接收所述装置的容纳部。
根据一个方面,用于将装置附接到使用者鼻子的鼻接口包括鼻芽,鼻芽具有包围通道的侧壁,侧壁的外部形状稍微呈台面形状,侧壁在一个端部处终止于扩口配件。
以上方面中的一个或多个可包括以下特征中的一个或多个。
所述接口的鼻芽具有鼻芽外侧壁,所述扩口配件一体地设置在所述鼻芽侧壁上,并且所述扩口配件的尺寸设计成允许使用者将所述鼻芽容易地插入到所述使用者的鼻子中。所述接口的鼻芽在气道压力呼吸装置和使用者的鼻子之间提供密封。所述扩口配件具有至少一个孔,所述孔连接到所述气道压力呼吸装置中的空气路径。所述接口的鼻芽具有外侧壁,所述外侧壁具有外部台面形状,所述扩口配件是所述鼻芽侧壁的延伸部。所述鼻芽具有外侧壁,所述外侧壁具有外部台面形状,所述扩口配件是所述鼻芽侧壁的延伸部,并且所述扩口配件具有在其端部部分之间的呈圆锥形的内部通路,在扩口部分处的第一端部部分具有比终止于气道压力呼吸装置的第二远端端部部分更大的开口。鼻芽的材料是柔软的顺应性的硬度软的(soft durometer)材料。所述鼻芽具有约110至150度的估计的鼻芽中心线角范围、30至50度的估计的鼻芽面角范围,并且所述鼻芽形状大体为矩圆形。所述鼻芽具有矩圆形且面积可在约30-90mm2的范围内的开口。鼻芽的材料是橡胶材料。
接口的每个鼻芽侧壁和每个相应的扩口配件整体地设置有鼻芽侧壁,且所述扩口配件的尺寸设计成允许使用者将所述鼻芽容易地插入到所述使用者的鼻子中。所述接口的所述鼻芽在装置和使用者的鼻子之间提供密封。所述鼻芽的材料是柔软的顺应性的硬度软的材料,并且所述接口具有约110至150度的估计的鼻芽中心线角范围、30-50度的估计的鼻芽面角范围,并且鼻芽外侧壁和扩口配件具有大体为台面形状的形状。所述鼻芽具有穿过其中的开口,所述开口是大体矩圆形的并且面积在约30-90mm2的范围内。
所述接口的每个鼻芽在所述扩口配件和所述第二相对远端端部之间具有由内部圆锥形侧壁设置的内部通路。所述鼻芽在接口所附接的装置和使用者鼻子的鼻孔之间提供密封。所述鼻芽的材料是柔软的顺应性的硬度软的材料,并且所述接口具有约110至150度的鼻芽中心线角范围和30-50度的鼻芽面角范围。每个鼻芽的扩口配件具有通向相应通道的开口,该开口是矩圆形的并且面积在30-90mm2的范围内。
接口的鼻芽在所述侧壁的第二相对远端端部处具有容纳部以接收装置。所述鼻芽的材料是柔软的顺应性的硬度软的材料,并且所述接口具有约110至150度的估计的鼻芽中心线角范围、30-50度的估计的鼻芽面角范围,并且鼻芽具有稍微呈漏斗形状的通路方式。所述接口包括附接到装置的两个鼻芽,并且每个鼻芽具有通向所述通道的开口,所述开口是矩圆形的并且表面面积在约30-90mm2的范围内。
一个或多个方面可包括以下优点中的一个或多个。
本申请涉及用于气道压力呼吸装置的鼻子到装置的接口的细节,如在转让给本发明受让人的美国公开专利申请US-2015-0267695-A1中大体描述的,该专利申请通过引用结合在此。接口保持使用者的鼻孔张开,并且可以有助于保持空气通路打开。铰接的鼻芽具有空气通道或孔,并由大体呈橡胶状的材料制成,当插入到使用者的鼻孔中时形成紧密配合。鼻芽可提供插入到鼻孔中的容易度,以及对鼻孔的严密密封。扩口/凸缘配件允许在鼻孔腔内的容易插入和舒适定位,以为使用者的鼻孔提供密封接口。通道的内部形状提供从宽(在插入到鼻孔中的部分)到窄(在固定到主体的部分处)的空气路径,其可以减少呼气期间的气流阻碍。也就是说,开口在通道的端部处的横截面积以及因此空间的容积提供渐变锥度以使呼气期间的阻力最小化。此外,该漏斗形表面可以是光滑表面以进一步最小化阻力。
在附图和下文描述中阐述了本发明的一个或多个实施方式的细节。根据说明书和附图以及权利要求,本发明的其他特征、目的和优点得以显现。
附图说明
图1-8是具有铰接的鼻接口的气道压力呼吸装置的各种视图;
图1A是图1的示意性横截面图,示出了细节。
具体实施方式
概述
本申请涉及用于气道压力呼吸装置的鼻子到装置的接口的细节,如在美国公开专利申请US-2015-0267695-A1中大致地描述的,该专利申请被转让给本发明的受让人并通过引用结合在此。在上述申请中描述了一种新颖的微型泵,其包括多个被划分的泵室的堆叠结构,并且使用较少的材料,承受较小的应力,并且使用比传统泵更少的功率来驱动。微型泵具有微米至毫米级的尺寸,并且可以提供宽范围的流速和压力,并且是上述申请中提到的所述CPAP装置的一部分。
现在参考图1-7,示出了用于治疗呼吸障碍的自主装置10(装置10)。在一些实施方式中,装置10是CPAP型(持续气道正压)呼吸装置10。然而,与CPAP机器不同,如在上述专利申请中讨论过的,装置10是鼻子局部的自主装置,其以所需压力提供所需量的气流以治疗各种呼吸障碍,例如阻塞性睡眠呼吸暂停(“OSA”)。在其他实施方式中,在没有微型泵和CPAP呼吸装置10的其他部件的情况下,这种装置10的套装可用于保持鼻孔打开并且可以有助于保持空气通路打开。
当用作CPAP装置10时,装置10包括容纳微型泵(未示出)部件的主体12、呼气阀(未示出)和鼻接口14,该鼻接口包括带衬垫的铰接鼻芽14a、14b,所述鼻芽具有穿过鼻芽14a、14b的空气通路或孔15a、15b。带衬垫的鼻芽由大体呈橡胶状的材料制成,当插入到使用者的鼻孔中时可形成紧密配合。
鼻芽14a、14b通过可以改变特性的容纳部附接到呼吸装置主体12,并提供至使用者鼻孔的接口。同时鼻芽执行将呼吸装置10保持在用于治疗的适当位置的主要功能。鼻芽14a、14b提供插入鼻孔的容易性以及对鼻孔的严密密封。容纳部的例子包括由主体接收的端口或仅仅是主体中的孔,并且接口固定到主体。
现在参考图1,示出了鼻芽14a、14b及其至呼吸装置主体12的附接。如图所示,鼻芽14a、14b在其端部部分17a、17b处具有扩口/凸缘配件16a、16b。扩口/凸缘配件16a、16b构造成易于插入在鼻孔腔内并舒适地定位,以提供至使用者鼻孔的密封接口。与鼻孔腔的密封接口允许呼吸畅通无阻。扩口/凸缘配件16a、16b一体地设置(例如,形成)在鼻芽侧壁上,并且其尺寸设计成允许使用者将鼻芽容易地插入到使用者的鼻子中,优选地用一只手,而不需要过度的调节运动。鼻芽在装置10和使用者的鼻子之间提供密封。在扩口/凸缘配件16a、16b内是至少一个孔,其连接到装置10中的空气路径(未示出)。
如图1A所示,鼻芽14a、14b在端部部分处具有扩口/凸缘配件16a、16b,并且外侧壁19a、19b具有大致台面状外部形状以牢固配合并固定到使用者的鼻孔,而鼻芽的内侧壁20a、20b稍微呈锥形或漏斗状,形成鼻芽通道21a、21b。还示意性地示出了CPAP装置的主体12,其将包括微型泵(未示出)并且具有联接到鼻芽通道21a、21b的一对通路12a、12b。
内侧壁20a、20b在固定到CPAP主体12的一个端部处具有一个末端,其具有进入到CPAP主体12中的相对窄的开口,并且该内侧壁20a、20b在内侧壁的第二远端端部处具有末端,其具有相对较宽的开口。通道21a、21b的内部形状提供从宽(在插入到鼻孔中的部分处)到窄(在固定到CPAP主体12的部分处)的空气路径,其可以减少呼气期间的气流阻碍。也就是说,通道21a、21b的端部处的开口的横截面积以及因此空间的容积提供渐变锥度以使呼气期间的阻力最小化。此外,该漏斗形状表面可以是光滑表面以进一步最小化阻力。
密封允许装置10在一容积中建立压力,该容积是装置主体12的内部工作容积和使用者的气道路径容积的组合。密封可以在高于CPAP(持续气道正压)治疗水平(小于20cmH2O)的压力极限以上也是有效的,以提供足够的压力裕度。可以设想,密封可以对至少34cmH2O是有效的。
鼻芽14a、14b的形状和尺寸是足够舒适的,以允许使用者入睡。突伸到鼻子中的材料量很少。鼻芽的材料是一种非常软的和顺应的材料,以舒适地放在人的鼻子里。在睡眠期的正常持续时间内任何偶然的摩擦、转动或对其作用的任何其他力期间,鼻芽14a、14b允许呼吸装置10在鼻子中保持在位。
现在参照图2,示出了将呼吸装置10安装到使用者的鼻子30中的插入过程。鼻芽(图示为14a)插入到使用者的鼻子30中。如图所示,凸缘配件(图示为16a)枢转到鼻孔中,以向鼻腔32提供气道密封。在一种实施方式中,每个鼻芽上的凸缘配件借助枢转通过向上运动而被插入,鼻芽朝向鼻腔进入到鼻子中,以在鼻腔和鼻接口之间提供合理的严密密封。
现在参考图3,示出了鼻芽(未标记)如何适配到人的鼻子30中。鼻芽的扩口/凸缘配件16a、16b与鼻子30的鼻孔突出部31a和隔膜隆起部31b形成密封。当使用者呼气时,鼻芽的形状允许鼻芽形成更严密的密封。呼气有助于使抵靠鼻孔部分的底部周边的密封更严密,并且有助于防止诸如CPAP的装置12在使用者呼气时被分离或吹出。一旦插入,装置10由带凸缘的配件16a、16b自支撑,因为这些带凸缘的配件抵靠鼻孔突出部31a和隔膜隆起部31b搁置。
现在参考图4,示出了估计的鼻芽中心线角范围。该估计的中心线角范围约为110度至150度。该范围可以根据个人的鼻子进行调节以获得更好的配合,或可以存在可适合大多数鼻子的多个主流角度。该估计的中心线角范围是每个鼻芽的中心线之间形成的角的范围。例如,可以通过允许主体12绕其中心线12'弯曲、例如经由铰链(未示出)或借助主体12的材料的特性,来进行调节,这将允许主体12在一定角范围上弯曲并保持弯曲形状。可以使用其他调节技术。
现在参考图5,示出了估计的鼻芽面角范围为30-50度。这可以根据个人的鼻子进行调节以获得更好的配合,或可以存在可适合大多数鼻子的多个主流角度。该估计的面角范围是在接触每个鼻芽的外端部表面的平面(或线)之间形成的角的范围。例如,可以通过借助鼻芽14a、14b的材料特性允许鼻芽绕其中心线(未示出)弯曲,或通过使鼻芽14a、14b壁如手风琴那样稍微可折叠并可重新定位而进行调节,这将允许鼻芽14a、14b在该角范围内定位并保持该位置。可以使用其他调节技术。
现在参考图6,示出了鼻芽形状在一些实施例中为大体矩圆形,以便逼近常见的鼻孔形状。这可以根据个人的鼻子进行调节以获得更好的配合,或可以存在可适合大多数鼻子的多个主流形状。鼻芽材料是顺应性的(compliant),但它被设计用于实现和保持一定的横截面气流面积。该材料是顺应性的硬度软的材料,允许配件顺应鼻孔形状。开口可以是矩圆形的,并且开口的敞开面积、例如敞开表面可以范围例如为约30-90mm2
用于鼻芽的材料可以是天然和合成橡胶或具有柔软但顺应性特性的任何其他材料。这样的材料的特征包括ASTM D2240肖氏A标尺硬度为10-70或ASTM D2240-00肖氏OO标尺硬度为50-100(ASTM国际标准组织,美国宾夕法尼亚州(ASTM International,PA.US))。可以使用其他标尺和范围。可以使用其他范围,例如肖氏A标尺硬度范围可以是10-90,或者ASTM D2240-00肖氏OO标尺硬度范围可以是30-100。材料应该是低过敏性的,等。一种合适的材料是硅树脂。
现在参考图7,示出了鼻芽在空气路径内的轮廓,其被设计用于使呼气期间的流动限制最小化。通道21a、21b的平滑的内扩口表面在呼气时使空气限制(对气流的阻碍)最小化。还示出了空气路径的直径,例如约4-7mm,以及在呼气期间最小化流动限制的长度。该长度可以被认为是包括两部分。一部分是鼻接口的长度,其主要基于鼻子形状,并且鼻接口的实际应用可以具有各种尺寸。另一部分是穿过鼻接口所附接到的装置10的主体12的长度,所述主体在该示例中是CPAP主体12。
现在参考图8,示出了控制适当的鼻芽插入深度的鼻芽相隔尺寸38。相隔尺寸38的范围约为0.15至0.25英寸。还示出了装置主体12的顶部表面12a,其提供抵靠鼻子30的止动件,以帮助定位鼻芽并防止过度插入。以虚线示出的是微型泵39,其容纳在装置主体12内。微型泵39以及CPAP装置10的其他部件在美国公布的专利申请US-2015-0267695-A1中公开,该专利申请通过引用结合在此。在公开的专利中,具有微型泵的CPAP装置具有替代的鼻接口。该公开的申请中所披露的替代鼻接口与本文所述的鼻接口的不同之处在于将在权利要求中阐述的若干方面。
可以组合这里描述的不同实施方式的元件以形成上面没有具体阐述的其他实施例。在本文所述的结构的元件可以被省略而不会对其操作产生不利影响。此外,各种单独的元件可以组合成一个或多个单独的元件以执行本文所述的功能。
其他实施例在以下权利要求的范围内。例如,装置主体12可以具有各种形状并且可以仅具有允许使用者通过鼻芽通道21a、21b呼吸环境空气的气道通路。在该实施方式中,装置10将不包括CPAP装置的特征部,例如微型泵等,其允许具有鼻芽的装置主体减轻使用者的打鼾。在一些实施方式中,该装置可主要包括固定到主体的鼻芽14a、14b。

Claims (29)

1.一种气道压力呼吸装置,包括:
主体,其具有穿过所述主体的一对空气通路,所述一对空气通路终止于一对端部部分,每个端部部分具有至少一个出口;
由主体支撑的微型泵,所述微型泵构造成将环境空气通过主体中的空气通路泵送到端部部分;和
直接地支撑在主体上的固定长度的鼻接口,所述鼻接口包括一对鼻芽,每个鼻芽具有固定长度的非波纹管侧壁,该非波纹管侧壁的内部部分提供穿过鼻接口的空气通路,鼻芽在第一端部处终止于非波纹管侧壁上的扩口配件,鼻芽在第二端部处终止于主体的端部部分的相应一个端部部分处,且扩口配件处的非波纹管侧壁的直径大于非波纹管侧壁的中心部分处的直径。
2.根据权利要求1所述的气道压力呼吸装置,其中,每个非波纹管侧壁具有一体地设置在非波纹管侧壁上的扩口配件,每个鼻芽的扩口配件具有延伸超出非波纹管侧壁的中心部分的外边缘,并且所述扩口配件的尺寸设计成与使用者的鼻子的鼻孔突出部和隔膜隆起部形成密封。
3.根据权利要求1所述的气道压力呼吸装置,其中,所述主体和鼻芽是可调节的,以在一对范围内分别提供中心线角度和面角度,以在所述气道压力呼吸装置和使用者的鼻子之间提供密封。
4.根据权利要求1所述的气道压力呼吸装置,其中,所述扩口配件具有至少一个孔。
5.根据权利要求1所述的气道压力呼吸装置,其中,所述扩口配件是鼻芽侧壁的延伸部。
6.根据权利要求1所述的气道压力呼吸装置,其中,所述鼻芽中的每个具有在其端部部分之间的呈圆锥形的内部通路,其中端部部分的第一端部具有比端部部分的远端的第二端部处更大的开口。
7.根据权利要求1所述的气道压力呼吸装置,其中,所述鼻芽的材料是柔软的顺应性的硬度软的材料。
8.根据权利要求1所述的气道压力呼吸装置,其中,所述鼻芽具有110至150度的估计的鼻芽中心线角范围、30至50度的估计的鼻芽面角范围,并且所述鼻芽形状为大体矩圆形。
9.根据权利要求1所述的气道压力呼吸装置,其中,所述鼻芽具有开口,所述开口为矩圆形的并且面积可在30-90mm2的范围内。
10.根据权利要求1所述的气道压力呼吸装置,其中,所述鼻芽的材料是橡胶状材料。
11.根据权利要求1所述的气道压力呼吸装置,其中,与所述鼻芽的高度相对应的相隔尺寸在0.15英寸至0.25英寸的范围内。
12.根据权利要求1所述的气道压力呼吸装置,其中,穿过每个鼻芽的空气通道由非波纹管侧壁的光滑内部部分限定,该通道具有穿过其的大体为矩圆形的在30-90mm2的面积范围内的开口,并且扩口配件处的第一开口的面积大于第二端部处的开口的面积。
13.一种能附接到使用者鼻子的装置,该装置包括:
主体,其具有穿过所述主体的一对空气通路,所述一对空气通路终止于一对端部部分,每个端部部分在该端部部分的第一表面中具有至少一个出口;和
直接地附接到主体的固定长度的鼻接口,所述鼻接口包括一对鼻芽,每个鼻芽具有固定长度的非波纹管侧壁,该非波纹管侧壁在第一端部处终止于悬在鼻芽的非波纹管侧壁上的扩口配件并在第二端部处终止于主体的所述一对空气通路的相应一个,该非波纹管侧壁的内部部分使空气通路延伸穿过鼻芽,扩口配件处的非波纹管侧壁的直径大于非波纹管侧壁的中心部分处的直径。
14.如权利要求13所述的装置,其中,每个鼻芽侧壁的扩口配件具有外边缘,该外边缘延伸超出非波纹管侧壁的中心部分,以与使用者的鼻子的鼻孔突出部和隔膜隆起部形成密封。
15.如权利要求13所述的装置,其中,每个非波纹管侧壁具有连续的弯曲外表面。
16.如权利要求13所述的装置,其中,所述鼻芽的材料是柔软的顺应性的硬度软的材料,并且所述鼻接口具有110至150度的估计的鼻芽中心线角范围、30-50度的估计的鼻芽面角范围。
17.根据权利要求13所述的装置,其中,所述鼻芽具有穿过其中的开口,所述开口是大体矩圆形的并且面积在30-90mm2的范围内。
18.根据权利要求13所述的装置,其中,与所述鼻芽的高度相对应的相隔尺寸在0.15英寸至0.25英寸的范围内。
19.根据权利要求13所述的装置,其中,穿过每个鼻芽的空气通道由非波纹管侧壁的光滑内部部分限定,该通道具有穿过其的大体为矩圆形的在30-90mm2的面积范围内的开口,并且扩口配件处的第一开口的面积大于第二端部处的开口的面积。
20.根据权利要求15所述的装置,其中,每个鼻芽的扩口配件具有外边缘,该外边缘延伸超过所述非波纹管侧壁的中心部分,其尺寸被设计为以与使用者的鼻子的鼻孔突出部和隔膜隆起部形成密封。
21.如权利要求17所述的装置,其中,所述鼻芽的材料是柔软的顺应性的硬度软的材料,并且所述鼻接口具有110至150度的估计的鼻芽中心线角范围、30-50度的估计的鼻芽面角范围,并且鼻芽具有稍微呈漏斗形状的通道。
22.根据权利要求17所述的装置,其中,鼻接口包括两个鼻芽,并且每个鼻芽具有通向内部通道的开口,所述开口是矩圆形的并且表面面积在30-90mm2的范围内。
23.一种用于将装置附接到使用者鼻子的鼻接口,所述接口包括:
一对鼻芽,每个鼻芽具有非波纹管侧壁,非波纹管侧壁的内表面包围内部通道,并在第一端部处具有非波纹管侧壁的外部部分,该外部部分悬在非波纹管侧壁上,并通过将所述鼻接口直接附接到一装置的主体的容纳部而终止于非波纹管侧壁的相对远端的第二端部处,该非波纹管侧壁的内部部分提供穿过鼻芽的空气通路,并且在非波纹管侧壁上的扩口配件处的非波纹管侧壁的直径大于非波纹管侧壁的中心部分处的直径。
24.根据权利要求23所述的接口,其中,所述鼻芽每个在所述扩口配件和相对远端的第二端部之间具有内部通路,所述内部通路由内部圆锥形的非波纹管侧壁提供。
25.根据权利要求23所述的接口,其中,每个非波纹管侧壁具有从第一端到第二端的单个连续的外部弯曲表面,以提供非波纹管侧壁,并且鼻芽在接口所附接到的装置和使用者的鼻子的鼻孔之间提供密封。
26.根据权利要求23所述的接口,其中,所述鼻芽的材料是柔软的顺应性的硬度软的材料,并且所述接口具有110至150度的鼻芽中心线角范围和30-50度的鼻芽面角范围。
27.如权利要求23所述的接口,其中,每个鼻芽的扩口配件具有通向相应通道的开口,该开口是矩圆形的并且面积在30-90mm2的范围内。
28.根据权利要求23所述的接口,其中,与所述鼻芽的高度相对应的相隔尺寸在0.15至0.25英寸的范围内。
29.根据权利要求23所述的接口,其中,穿过每个鼻芽的空气通道由非波纹管侧壁的光滑内部部分限定,该通道具有穿过其的大体为矩圆形的在30-90mm2的面积范围内的开口,并且扩口配件处的第一开口的面积大于第二端部处的开口的面积。
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AU2017295876A1 (en) 2019-02-14
EP3484564A4 (en) 2020-03-18
US20180015247A1 (en) 2018-01-18
CN109922853A (zh) 2019-06-21
WO2018013893A1 (en) 2018-01-18
JP2019521821A (ja) 2019-08-08

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