CN109893593A - A kind of Chinese medicine composition and preparation method thereof for treating tumour - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating tumour Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 239000002994 raw material Substances 0.000 claims abstract description 43
- 235000002639 sodium chloride Nutrition 0.000 claims abstract description 34
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Abstract
The invention discloses a kind of Chinese medicine compositions and preparation method thereof for treating tumour, belong to modern Chinese traditional medicine field.A kind of Chinese medicine composition for treating tumour, active constituent are prepared from the following raw materials in parts by weight: 1600 parts of Prunella vulgaris, 200 parts of fritillaria thunbergii, 200 parts of seaweed, 200 parts of radix ampelopsis, 200 parts of radices trichosanthis, 200 parts of Fructus Forsythiae, 200 parts of prepared RADIX ET RHIZOMA RHEI, 200 parts of the compound of glauber-salt and liquorice, 200 parts of clam shell (forging), 200 parts of halite, 200 parts of Fructus Aurantii, 200 parts of campanulaceae, 1 part of menthol, 200 parts of glutinous rehmannia, 200 parts of Radix Angelicae Sinensis, 1000 parts of radix scrophulariae, 200 parts of Radix Glycyrrhizae.The features of the present invention: according to the result of study of each flavour of a drug ingredient physicochemical property and pharmacological action, the preparation method of the active constituent of reasonably stability is obtained.The drug quality prepared using technical solution of the present invention is stably and controllable, and curative effect is significantly increased than existing sale dosage form, and taking dose is reduced, and has significant economic and social benefit.
Description
Technical field
The present invention relates to a kind of Chinese medicine compositions and preparation method thereof for treating tumour, belong to modern Chinese traditional medicine field.
Background technique
Scrofula subcutaneous nodule refers to the limitation mass of body surface.The disease is not transported because spleen is weak mostly, and damp phlegm knot gathers to be formed in subcutaneously.Disease
See intradermal raw core, more or less, and mass is not not red warm, and bitterly not hard, what is pushed away is removable, is mainly in neck, lower chin, four limbs and back
Etc..Control preferably with clear phlegm it is gentle based on.The person that is born in upper body part holds wind-heat under the arm more, be born in lower part person then hold under the arm it is damp and hot.It is bright that " careful vegetarian is lost
Book " volume nine.Have: " subcutaneous nodule, i.e. scrofula, shaoyang channel stagnated fire are tied." Neixiao Luoli Pian is that current market sales of one kind is controlled
Treat the Chinese medicine of tumour.For scrofula subcutaneous nodule or swollen or pain.
The prescription and preparation method of Neixiao Luoli Pian are as follows: Prunella vulgaris 400g, fritillaria thunbergii 50g, seaweed 50g, radix ampelopsis 50g, radices trichosanthis
50g, Fructus Forsythiae 50g, prepared RADIX ET RHIZOMA RHEI 50g, compound of glauber-salt and liquorice 50g, clam shell (forge) 50g, halite 50g, Fructus Aurantii 50g, campanulaceae 50g, menthol
0.25g, glutinous rehmannia 50g, Radix Angelicae Sinensis 50g, radix scrophulariae 250g, Radix Glycyrrhizae 50g.Halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, smallpox
Powder is ground into fine powder, and menthol is dissolved with ethanol in proper amount；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add water to cook it is secondary,
Prunella vulgaris adds water to cook 5 hours, merges the above decocting liquid, is condensed into thick paste；Radix Angelicae Sinensis is respectively heated back with 95% ethyl alcohol and 60% ethyl alcohol
Stream extracts primary；Campanulaceae, 60% ethyl alcohol heating and refluxing extraction of Fructus Aurantii.Merge the above ethanol extract, recycles ethyl alcohol, be condensed into
Thick paste.Above-mentioned condensed cream is merged, powder and the auxiliary materials such as halite is added, mixes, particle is made, it is dry, menthol second is added
Alcoholic solution, mix, it is tabletted to get.
Summary of the invention
The invention solves first technical problem be to provide a kind of Chinese medicine composition for treating tumour.
The invention solves another technical problem be to provide the preparation method of above-mentioned Chinese medicine composition.
To achieve the above object, the present invention uses following technical scheme；
A kind of Chinese medicine composition for treating tumour, active constituent are prepared from the following raw materials in parts by weight: Prunella vulgaris
1600 parts, it is 200 parts of fritillaria thunbergii, 200 parts of seaweed, 200 parts of radix ampelopsis, 200 parts of radices trichosanthis, 200 parts of Fructus Forsythiae, 200 parts of prepared RADIX ET RHIZOMA RHEI, profound bright
200 parts of powder, 200 parts of clam shell (forging), 200 parts of halite, 200 parts of Fructus Aurantii, 200 parts of campanulaceae, 1 part of menthol, 200 parts of glutinous rehmannia, when
Return 200 parts, 1000 parts of radix scrophulariae, 200 parts of Radix Glycyrrhizae.
The active constituent is prepared using following methods:
1, each raw material is weighed by raw material proportioning；Halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, radices trichosanthis are ground into
Fine powder, menthol are dissolved with ethanol in proper amount；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add water to cook secondary, and Prunella vulgaris adds
Water decocts 5 hours, merges the above decocting liquid, is condensed into thick paste；95% ethyl alcohol of Radix Angelicae Sinensis and each heating and refluxing extraction one of 60% ethyl alcohol
It is secondary；Campanulaceae, 60% ethyl alcohol heating and refluxing extraction of Fructus Aurantii.Merge the above ethanol extract, recycles ethyl alcohol, be condensed into thick paste.It will
Above-mentioned condensed cream merges, and powder and the auxiliary materials such as halite is added, and mixes, particle is made, dry, and menthol ethanol solution is added,
It mixes, obtains dried object A.
2, each raw material is weighed by raw material proportioning；Halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, radices trichosanthis are ground into
Fine powder, menthol are dissolved with ethanol in proper amount；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add water to cook secondary, press for the first time
The extraordinarily water of the 10 of raw material weight, heating are boiled to boiling, are kept for 3 hours；Second by raw material weight 8 extraordinarily water, heating boil to
Boiling is kept for 2 hours.Extracting solution is filtered through 100 mesh filters, is placed in receiver, stands 1 hour.Prunella vulgaris adds water to cook
It is secondary, it is boiled to boiling, is kept for 3 hours by 10 extraordinarily water, heating of raw material weight for the first time；8 times for pressing raw material weight for the second time
Add water, heating is boiled to boiling, kept for 2 hours.Extracting solution is filtered through 100 mesh filters, is placed in receiver, stands 1 hour.It closes
And the above decocting liquid, it is condensed into thick paste.Radix Angelicae Sinensis is secondary with ethyl alcohol heating and refluxing extraction, presses the 3 extraordinarily 95% of raw material weight for the first time
Ethyl alcohol, heating and refluxing extraction are kept for 3 hours；Second of 3 extraordinarily 60% ethyl alcohol by raw material weight, heating and refluxing extraction are kept
3 hours.Extracting solution is filtered through 100 mesh filters, is placed in receiver, stands 1 hour.Campanulaceae, Fructus Aurantii are heated to reflux with ethyl alcohol
It extracts secondary.3.5 extraordinarily 60% ethyl alcohol of raw material weight are pressed for the first time, and heating and refluxing extraction is kept for 3 hours.Second by use
Extraordinarily 60% ethyl alcohol of the 2.5 of raw material weight, heating and refluxing extraction are kept for 2 hours, press extraordinarily 60% second of raw material weight 2 for the third time
Alcohol, heating and refluxing extraction are kept for 1 hour.Extracting solution is filtered through 100 mesh filters, is placed in receiver, stands 1 hour.Merge
The above ethanol extract recycles ethyl alcohol, is condensed into thick paste.Above-mentioned condensed cream is merged, halite, fritillaria thunbergii, clam shell is added, it is ripe
Rheum officinale, the compound of glauber-salt and liquorice, the powder such as radices trichosanthis and auxiliary material mix, particle are made, dry, and menthol ethanol solution is added, and mix, obtain
To dried object A.
Described pharmaceutical composition also contains pharmaceutically acceptable auxiliary material.
The pharmaceutically acceptable auxiliary material is selected from starch, microcrystalline cellulose, sucrose, Aspartame, dextrin, lactose, sugar
Powder, glucose, sodium chloride, sodium cellulose glycolate, crosslinked polyvinylpyrrolidone, magnesium stearate, superfine silica gel powder, vitamin C,
Any one or a few in cysteine, citric acid and sodium sulfite.
The dosage form of the Chinese medicine composition is peroral dosage form, including but not limited to pill, tablet, capsule or oral solution.Agent
The selection of type and the dosage of auxiliary material belong to the prior art.
A kind of preparation method of Chinese medicine composition that treating tumour:
Weigh 1600 parts of Prunella vulgaris, 200 parts of fritillaria thunbergii, 200 parts of seaweed, 200 parts of radix ampelopsis, 200 parts of radices trichosanthis, Fructus Forsythiae 200
Part, 200 parts of prepared RADIX ET RHIZOMA RHEI, 200 parts of the compound of glauber-salt and liquorice, 200 parts of clam shell (forging), 200 parts of halite, 200 parts of Fructus Aurantii, 200 parts of campanulaceae, peppermint
1 part of brain, 200 parts of glutinous rehmannia, 200 parts of Radix Angelicae Sinensis, 1000 parts of radix scrophulariae, 200 parts of Radix Glycyrrhizae.Halite, fritillaria thunbergii, clam shell, it is prepared RADIX ET RHIZOMA RHEI, profound bright
Powder, radices trichosanthis are ground into fine powder, and menthol is dissolved with ethanol in proper amount；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add decocting
Boil secondary, Prunella vulgaris adds water to cook 5 hours, merges the above decocting liquid, is condensed into thick paste；95% ethyl alcohol of Radix Angelicae Sinensis and 60% ethyl alcohol are each
Heating and refluxing extraction is primary；Campanulaceae, 60% ethyl alcohol heating and refluxing extraction of Fructus Aurantii.Merge the above ethanol extract, recycle ethyl alcohol,
It is condensed into thick paste.Above-mentioned condensed cream is merged, powder and the auxiliary materials such as halite is added, mixes, particle is made, it is dry, it is added thin
Lotus brain ethanol solution mixes, obtains dried object A.
Preferably the preparation method comprises the following steps: 1600 parts of Prunella vulgaris, 200 parts of fritillaria thunbergii, 200 parts of seaweed, 200 parts of radix ampelopsis, radices trichosanthis
200 parts, 200 parts of Fructus Forsythiae, 200 parts of prepared RADIX ET RHIZOMA RHEI, 200 parts of the compound of glauber-salt and liquorice, 200 parts of clam shell (forging), 200 parts of halite, 200 parts of Fructus Aurantii,
200 parts of campanulaceae, 1 part of menthol, 200 parts of glutinous rehmannia, 200 parts of Radix Angelicae Sinensis, 1000 parts of radix scrophulariae, 200 parts of Radix Glycyrrhizae.Halite, fritillaria thunbergii, clam
Shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, radices trichosanthis are ground into fine powder, and menthol is dissolved with ethanol in proper amount；It is Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, sweet
Grass, radix scrophulariae add water to cook secondary, and for the first time by 10 extraordinarily water of raw material weight, heating is boiled to boiling, is kept for 3 hours；Second
It is boiled to boiling, is kept for 2 hours by 8 extraordinarily water, heating of raw material weight.Extracting solution is filtered through 100 mesh filters, is placed in receiver
In, stand 1 hour.Prunella vulgaris adds water to cook secondary, and for the first time by 10 extraordinarily water of raw material weight, heating is boiled to boiling, keeps 3
Hour；Second of 8 extraordinarily water, heating for pressing raw material weight is boiled to boiling, is kept for 2 hours.Extracting solution is through 100 mesh filter mistakes
Filter, is placed in receiver, stands 1 hour.Merge the above decocting liquid, is condensed into thick paste.Radix Angelicae Sinensis is secondary with ethyl alcohol heating and refluxing extraction,
3 extraordinarily 95% ethyl alcohol of raw material weight are pressed for the first time, and heating and refluxing extraction is kept for 3 hours；3 times for pressing raw material weight for the second time
Add 60% ethyl alcohol, heating and refluxing extraction is kept for 3 hours.Extracting solution is filtered through 100 mesh filters, is placed in receiver, stands 1
Hour.Campanulaceae, Fructus Aurantii are secondary with ethyl alcohol heating and refluxing extraction.3.5 extraordinarily 60% ethyl alcohol for pressing raw material weight for the first time, are heated back
Stream extracts, and is kept for 3 hours.Second of 2.5 extraordinarily 60% ethyl alcohol pressed with raw material weight, heating and refluxing extraction are kept for 2 hours,
Third time presses extraordinarily 60% ethyl alcohol of raw material weight 2, and heating and refluxing extraction is kept for 1 hour.Extracting solution is filtered through 100 mesh filters,
It is placed in receiver, stands 1 hour.Merge the above ethanol extract, recycles ethyl alcohol, be condensed into thick paste.Above-mentioned condensed cream is closed
And halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, the powder such as radices trichosanthis and auxiliary material is added, it mixes, particle is made, do
It is dry, menthol ethanol solution is added, mixes, obtains dried object A.
A kind of preparation of Chinese medicine composition that treating tumour, said preparation are added pharmacy with above-mentioned active pharmaceutical ingredient and can connect
Pharmaceutically acceptable dosage form is made in the auxiliary material received.Needed for prepared by the active constituent of the Chinese medicine composition obtained using the present invention
When the various dosage forms of drug, it can be prepared according to the conventional production process of art of pharmacy.Such as by the active constituent and it is a kind of or
Variety carrier mixing, is then made corresponding dosage form.
The invention has the advantages that the present invention analyzes composition with theory of traditional Chinese medical science, according to the reason of each flavour of a drug ingredient
Change property and pharmacological action, research has obtained the preparation method of reasonable, stable active constituent.Using technical side of the invention
Case, stable and controllable for quality, curative effect significantly improves compared with existing commercial dosage forms, the pharmaceutical preparation of patient's taking dose reduction, tool
There is significant economic and social benefit.
Technical solution that the present invention will be described in detail by the following examples, does not limit practical range of the invention with this.
Specific embodiment
Embodiment 1: Chinese medical extract is prepared
One, prescription: Prunella vulgaris 400g, fritillaria thunbergii 50g, seaweed 50g, radix ampelopsis 50g, radices trichosanthis 50g, Fructus Forsythiae 50g, prepared RADIX ET RHIZOMA RHEI
50g, compound of glauber-salt and liquorice 50g, clam shell (forge) 50g, halite 50g, Fructus Aurantii 50g, campanulaceae 50g, menthol 0.25g, glutinous rehmannia 50g, Radix Angelicae Sinensis
50g, radix scrophulariae 250g, Radix Glycyrrhizae 50g
Two, preparation method:
Halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, radices trichosanthis are ground into fine powder, and menthol ethanol in proper amount is molten
Solution；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add water to cook secondary, and Prunella vulgaris adds water to cook 5 hours, merge above decoct
Liquid is condensed into thick paste；95% ethyl alcohol of Radix Angelicae Sinensis and each heating and refluxing extraction of 60% ethyl alcohol are primary；Campanulaceae, 60% ethyl alcohol of Fructus Aurantii
Heating and refluxing extraction.Merge the above ethanol extract, recycles ethyl alcohol, be condensed into thick paste.Above-mentioned condensed cream is merged, smalt is added
The powder such as salt and auxiliary material mix, particle are made, dry, and menthol ethanol solution is added, and mix, should go out granule number 853g.
Embodiment 2: Chinese medical extract is prepared
One, prescription: Prunella vulgaris 400kg, fritillaria thunbergii 50kg, seaweed 50kg, radix ampelopsis 50kg, radices trichosanthis 50kg, Fructus Forsythiae 50kg,
Prepared RADIX ET RHIZOMA RHEI 50kg, compound of glauber-salt and liquorice 50kg, clam shell (forge) 50kg, halite 50kg, Fructus Aurantii 50kg, campanulaceae 50kg, menthol 0.25kg,
Glutinous rehmannia 50kg, Radix Angelicae Sinensis 50kg, radix scrophulariae 250kg, Radix Glycyrrhizae 50kg.
Two, preparation method:
Halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, radices trichosanthis are ground into fine powder, and menthol ethanol in proper amount is molten
Solution；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add water to cook secondary, and Prunella vulgaris adds water to cook 5 hours, merge above decoct
Liquid is condensed into thick paste；95% ethyl alcohol of Radix Angelicae Sinensis and each heating and refluxing extraction of 60% ethyl alcohol are primary；Campanulaceae, 60% ethyl alcohol of Fructus Aurantii
Heating and refluxing extraction.Merge the above ethanol extract, recycles ethyl alcohol, be condensed into thick paste.Above-mentioned condensed cream is merged, smalt is added
The powder such as salt and auxiliary material mix, particle are made, dry, and menthol ethanol solution is added, and mix, should go out granule number 853kg.
Embodiment 3: tablet is prepared
The active constituent 100g that embodiment 1 obtains, adds microcrystalline cellulose 40g, cross-linked pvp 7g, tabletting, obtains tablet, and every
Weight 0.60g.
Embodiment 4: capsule is prepared
The active constituent 1000g that embodiment 2 obtains, adds starch 250g, and encapsulating capsule obtains capsule, every weight 0.50g.
Claims (8)
1. a kind of Chinese medicine composition for treating tumour, active constituent are prepared from the following raw materials in parts by weight: Prunella vulgaris 1600
Part, 200 parts of fritillaria thunbergii, 200 parts of seaweed, 200 parts of radix ampelopsis, 200 parts of radices trichosanthis, 200 parts of Fructus Forsythiae, 200 parts of prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice
200 parts, 200 parts of clam shell (forging), 200 parts of halite, 200 parts of Fructus Aurantii, 200 parts of campanulaceae, 1 part of menthol, 200 parts of glutinous rehmannia, Radix Angelicae Sinensis
200 parts, 1000 parts of radix scrophulariae, 200 parts of Radix Glycyrrhizae.
2. a kind of Chinese medicine composition for treating tumour according to claim 1, it is characterised in that the active constituent uses
Following methods are prepared: halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, and radices trichosanthis is ground into fine powder, and menthol is used suitable
Measure ethyl alcohol dissolution；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add water to cook secondary, and Prunella vulgaris adds water to cook 5 hours, merge
The above decocting liquid, is condensed into thick paste；95% ethyl alcohol of Radix Angelicae Sinensis and each heating and refluxing extraction of 60% ethyl alcohol are primary；Campanulaceae, Fructus Aurantii are used
60% ethyl alcohol heating and refluxing extraction merges the above ethanol extract, recycles ethyl alcohol, is condensed into thick paste, above-mentioned condensed cream is merged,
Powder and the auxiliary materials such as halite is added, mixes, particle is made, it is dry, menthol ethanol solution is added, mixes, obtains dried object
A。
3. a kind of Chinese medicine composition for treating tumour according to claim 2, it is characterised in that: halite, fritillaria thunbergii, clam
Shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, radices trichosanthis are ground into fine powder, and menthol is dissolved with ethanol in proper amount；It is Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, sweet
Grass, radix scrophulariae add water to cook secondary, and for the first time by 10 extraordinarily water of raw material weight, heating is boiled to boiling, is kept for 3 hours；Second
It is boiled to boiling, is kept for 2 hours, extracting solution is filtered through 100 mesh filters, is placed in receiver by 8 extraordinarily water, heating of raw material weight
In, 1 hour is stood, Prunella vulgaris adds water to cook secondary, and for the first time by 10 extraordinarily water of raw material weight, heating is boiled to boiling, keeps 3
Hour；Second of 8 extraordinarily water, heating for pressing raw material weight is boiled to boiling, is kept for 2 hours, extracting solution is through 100 mesh filter mistakes
Filter, is placed in receiver, stands 1 hour, merges the above decocting liquid, be condensed into thick paste, and Radix Angelicae Sinensis is secondary with ethyl alcohol heating and refluxing extraction,
3 extraordinarily 95% ethyl alcohol of raw material weight are pressed for the first time, and heating and refluxing extraction is kept for 3 hours；3 times for pressing raw material weight for the second time
Add 60% ethyl alcohol, heating and refluxing extraction is kept for 3 hours, and extracting solution is filtered through 100 mesh filters, is placed in receiver, stands 1
Hour, campanulaceae, Fructus Aurantii are secondary with ethyl alcohol heating and refluxing extraction, press 3.5 extraordinarily 60% ethyl alcohol of raw material weight for the first time, heat back
Stream extracts, and is kept for 3 hours, and second of 2.5 extraordinarily 60% ethyl alcohol pressed with raw material weight, heating and refluxing extraction is kept for 2 hours,
Third time presses extraordinarily 60% ethyl alcohol of raw material weight 2, and heating and refluxing extraction is kept for 1 hour, and extracting solution is filtered through 100 mesh filters,
It is placed in receiver, stands 1 hour, merge the above ethanol extract, recycle ethyl alcohol, be condensed into thick paste, above-mentioned condensed cream is closed
And halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, the powder such as radices trichosanthis and auxiliary material is added, it mixes, particle is made, do
It is dry, menthol ethanol solution is added, mixes, obtains dried object A.
4. according to claim 1 to a kind of Chinese medicine composition for treating tumour described in any one of 3, it is characterised in that: institute
Belong to drug and also contains pharmaceutically acceptable auxiliary material.
5. a kind of Chinese medicine composition for treating tumour according to claim 4, it is characterised in that: the pharmacy is acceptable
Auxiliary material to be selected from starch, microcrystalline cellulose, sucrose, Aspartame, dextrin, lactose, Icing Sugar, glucose, sodium chloride, methylol fine
Tie up plain sodium, crosslinked polyvinylpyrrolidone, magnesium stearate, superfine silica gel powder, vitamin C, cysteine, citric acid and sodium sulfite
In any one or a few.
6. a kind of Chinese medicine composition of enriching yin and nourishing kidney according to claim 4, it is characterised in that: the Chinese medicine composition
Dosage form is peroral dosage form, including pill, tablet, capsule or oral solution.
7. a kind of preparation method for the Chinese medicine composition for treating tumour, it is characterised in that: 1600 parts of Prunella vulgaris, 200 parts of fritillaria thunbergii,
200 parts of seaweed, 200 parts of radix ampelopsis, 200 parts of radices trichosanthis, 200 parts of Fructus Forsythiae, 200 parts of prepared RADIX ET RHIZOMA RHEI, 200 parts of the compound of glauber-salt and liquorice, clam shell (forging) 200
Part, 200 parts of halite, 200 parts of Fructus Aurantii, 200 parts of campanulaceae, 1 part of menthol, 200 parts of glutinous rehmannia, 200 parts of Radix Angelicae Sinensis, 1000 parts of radix scrophulariae,
200 parts of Radix Glycyrrhizae, halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, radices trichosanthis is ground into fine powder, menthol ethanol in proper amount
Dissolution；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add water to cook secondary, and Prunella vulgaris adds water to cook 5 hours, merge above decoct
Liquid is condensed into thick paste；95% ethyl alcohol of Radix Angelicae Sinensis and each heating and refluxing extraction of 60% ethyl alcohol are primary；Campanulaceae, 60% ethyl alcohol of Fructus Aurantii
Heating and refluxing extraction merges the above ethanol extract, recycles ethyl alcohol, is condensed into thick paste, above-mentioned condensed cream is merged, and smalt is added
The powder such as salt and auxiliary material mix, particle are made, dry, and menthol ethanol solution is added, and mix, obtain dried object A.
8. a kind of Chinese medicine composition for treating tumour according to claim 1 according to claim 7, feature exist
In: 1600 parts of Prunella vulgaris, 200 parts of fritillaria thunbergii, 200 parts of seaweed, 200 parts of radix ampelopsis, 200 parts of radices trichosanthis, 200 parts of Fructus Forsythiae, prepared RADIX ET RHIZOMA RHEI
200 parts, 200 parts of the compound of glauber-salt and liquorice, 200 parts of clam shell (forging), 200 parts of halite, 200 parts of Fructus Aurantii, 200 parts of campanulaceae, 1 part of menthol,
Yellow 200 parts, 200 parts of Radix Angelicae Sinensis, 1000 parts of radix scrophulariae, 200 parts of Radix Glycyrrhizae, halite, fritillaria thunbergii, clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, smallpox
Powder is ground into fine powder, and menthol is dissolved with ethanol in proper amount；Fructus Forsythiae, seaweed, radix ampelopsis, glutinous rehmannia, Radix Glycyrrhizae, radix scrophulariae add water to cook it is secondary,
It is boiled to boiling, is kept for 3 hours by 10 extraordinarily water, heating of raw material weight for the first time；Second by raw material weight 8 extraordinarily water,
Heating is boiled to boiling, is kept for 2 hours, and extracting solution is filtered through 100 mesh filters, is placed in receiver, stands 1 hour, Prunella vulgaris
Add water to cook secondary, for the first time by 10 extraordinarily water of raw material weight, heating is boiled to boiling, is kept for 3 hours；Second by raw material weight
The extraordinarily water of the 8 of amount, heating are boiled to boiling, are kept for 2 hours, and extracting solution is filtered through 100 mesh filters, is placed in receiver, stand 1
Hour, merge the above decocting liquid, be condensed into thick paste, Radix Angelicae Sinensis is secondary with ethyl alcohol heating and refluxing extraction, 3 times for pressing raw material weight for the first time
Add 95% ethyl alcohol, heating and refluxing extraction is kept for 3 hours；Second of 3 extraordinarily 60% ethyl alcohol by raw material weight is heated to reflux and mentions
It takes, is kept for 3 hours, extracting solution is filtered through 100 mesh filters, is placed in receiver, stands 1 hour, campanulaceae, Fructus Aurantii are added with ethyl alcohol
Circumfluence distillation is secondary, for the first time press raw material weight 3.5 extraordinarily 60% ethyl alcohol, heating and refluxing extraction, keep 3 hours, second
Secondary 2.5 extraordinarily 60% ethyl alcohol by with raw material weight, heating and refluxing extraction are kept for 2 hours, press raw material weight 2 extraordinarily for the third time
60% ethyl alcohol, heating and refluxing extraction are kept for 1 hour, and extracting solution is filtered through 100 mesh filters, are placed in receiver, and it is small to stand 1
When, merge the above ethanol extract, recycle ethyl alcohol, be condensed into thick paste, above-mentioned condensed cream is merged, be added halite, fritillaria thunbergii,
Clam shell, prepared RADIX ET RHIZOMA RHEI, the compound of glauber-salt and liquorice, the powder such as radices trichosanthis and auxiliary material mix, particle are made, dry, and menthol ethanol solution is added,
It mixes, obtains dried object A.
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