Summary of the invention
Based on this, it is necessary to which the technical issues of structure is complicated for traditional lingual nerve stimulator provides a kind of lingual nerve
Electrical stimulation device.
A kind of electrical stimulation device of lingual nerve, comprising: electrod-array, wireless communication module, controller, pulse generation electricity
Road, first medium substrate, second medium substrate and third dielectric substrate;Wherein, first medium substrate second medium substrate and
Three dielectric substrates it is in the same size, and first medium substrate, second medium substrate and third dielectric substrate all have specific shape;
Controller passes through pulse generating circuit connection electrode array;Controller connects wireless communication module;Electrod-array collection
At being arranged on first medium substrate, controller and pulse generating circuit are integrally disposed on second medium substrate, wireless communication
Module is integrally disposed on third dielectric substrate;First medium substrate, second medium substrate and third dielectric substrate are successively bonded.
Module receives the Slope Parameters that terminal is sent, foundation to controller by wireless communication in one of the embodiments,
The pulse parameter of Slope Parameters adjusting pulse generating circuit;Wherein, Slope Parameters characterize the first user in each of monitoring period of time
The duration variation tendency of particular state is in statistical time range;Monitoring period of time is that the lingual nerve of the first user receives electro photoluminescence process
In period.
As one embodiment, controller is negative value recognizing Slope Parameters, and the absolute value of Slope Parameters is greater than the
When one adjusting threshold value, pulse parameter is turned down;It is positive value recognizing Slope Parameters, and the absolute value of Slope Parameters is greater than second and adjusts
When saving threshold value, pulse parameter is tuned up.
As one embodiment, pulse parameter includes impulse amplitude and pulse duty factor;
Controller turns impulse amplitude down first setting ratio;And/or turn pulse duty factor down second setting ratio,
To turn the pulse parameter down;
Impulse amplitude is tuned up the first setting ratio by controller;And/or pulse duty factor is tuned up into the second setting ratio,
To tune up pulse parameter.
As one embodiment, controller is recognizing Slope Parameters less than or equal to the second adjusting threshold value, and is greater than
Or when adjusting the opposite number of threshold value equal to first, keep pulse parameter constant.
Terminal obtains the statistics that the first user is in particular state in multiple statistical time ranges in one of the embodiments,
Duration determines Slope Parameters according to the statistics duration of each statistical time range.Above-mentioned monitoring period of time includes multiple statistical time ranges.
The electrical stimulation device of above-mentioned lingual nerve further includes power supply module, power supply module difference in one of the embodiments,
Connect wireless communication module, controller and pulse generating circuit;Power supply module is arranged on second medium substrate.
As one embodiment, above-mentioned power supply module is rechargeable battery;
The electrical stimulation device of lingual nerve further includes charge coil;Charge coil connects rechargeable battery;Charge coil setting
On third dielectric substrate.
The electrical stimulation device of above-mentioned lingual nerve further includes remote controler in one of the embodiments,;Remote controler passes through wireless
Communication module is communicated with controller;
Remote controler is used to read the control instruction of user, and by control instruction, module is sent to controller by wireless communication;
Controller controls pulse generating circuit according to control instruction and issues pulse signal.
Each electrode of electrod-array is uniformly arranged on first medium substrate in one of the embodiments,.
Electrod-array can be integrally disposed on first medium substrate, controller by the electrical stimulation device of above-mentioned lingual nerve
It being integrally disposed on second medium substrate with pulse generating circuit, wireless communication module is integrally disposed on third dielectric substrate,
The structure of electrical stimulation device made of first medium substrate, second medium substrate and third dielectric substrate are successively bonded in this way obtains
Effectively simplify, can directly be affixed on relative users tongue, make controller therein by wireless communication module receive it is external
The control instruction control pulse generating circuit of equipment generates pulse signal, so that it is corresponding so that electrod-array is issued stimulation behavior stimulation
The lingual nerve of user can be improved relative users and receive the comfort level in lingual nerve stimulating course.
Specific embodiment
To make the objectives, technical solutions, and advantages of the present invention more comprehensible, with reference to the accompanying drawings and embodiments, to this
Invention is described in further detail.It should be appreciated that the specific embodiments described herein are only used to explain the present invention,
And the scope of protection of the present invention is not limited.
It should be noted that term involved in the embodiment of the present invention " first second third " be only distinguish it is similar
Object does not represent the particular sorted for object, it is possible to understand that ground, " first second third " can be mutual in the case where permission
Change specific sequence or precedence.It should be understood that the object that " first second third " is distinguished in the appropriate case can be mutual
It changes, so that the embodiment of the present invention described herein can be real with the sequence other than those of illustrating or describing herein
It applies.
The term " includes " of the embodiment of the present invention and " having " and their any deformations, it is intended that cover non-exclusive
Include.Such as contain series of steps or module process, method, system, product or equipment be not limited to it is listed
Step or module, but optionally further comprising the step of not listing or module, or optionally further comprising for these processes, side
Method, product or equipment intrinsic other steps or module.
Referenced herein " embodiment " is it is meant that a particular feature, structure, or characteristic described can wrap in conjunction with the embodiments
It is contained at least one embodiment of the application.Each position in the description occur the phrase might not each mean it is identical
Embodiment, nor the independent or alternative embodiment with other embodiments mutual exclusion.Those skilled in the art explicitly and
Implicitly understand, embodiment described herein can be combined with other embodiments.
Referenced herein " multiple " refer to two or more."and/or", the association for describing affiliated partner are closed
System indicates may exist three kinds of relationships, for example, A and/or B, can indicate: individualism A exists simultaneously A and B, individualism
These three situations of B.Character "/" typicallys represent the relationship that forward-backward correlation object is a kind of "or".
The electrical stimulation device structural schematic diagram of the lingual nerve of one embodiment, above-mentioned lingual nerve are shown with reference to Fig. 3, Fig. 3
Electrical stimulation device include: electrod-array 11, wireless communication module 13, controller 15, pulse generating circuit 17, first medium base
Piece (being not shown in Fig. 3), second medium substrate (being not shown in Fig. 3) and third dielectric substrate (being not shown in Fig. 3);Wherein,
One dielectric substrate, second medium substrate and third dielectric substrate it is in the same size, and first medium substrate, second medium substrate and
Third dielectric substrate all has specific shape;
Controller 15 passes through 17 connection electrode array 11 of pulse generating circuit;Controller 15 connects wireless communication module 13;
Electrod-array 11 is integrally disposed on first medium substrate, and controller 15 and pulse generating circuit 17 are integrally disposed in second medium
On substrate, wireless communication module 13 is integrally disposed on third dielectric substrate;First medium substrate, second medium substrate and third
Dielectric substrate is successively bonded.
First medium substrate, second medium substrate and third dielectric substrate can be respectively printed circuit board (PCB route
Plate).Specifically, it is successively bonded in above-mentioned first medium substrate, second medium substrate and third dielectric substrate, it is integrated to obtain device
After structure, part in addition to an electrode in the insulating materials coating unit integrated morphology such as silica gel or plastic film can be used,
First medium substrate, the part of second medium substrate and third dielectric substrate surface in addition to an electrode i.e. after cladding fitting,
The safety and on the basis of comfort level in this way in guaranteeing user's use process, is exposed to the electrode for issuing stimulation movement outer,
So that electrode and tongue directly contact, more effective electro photoluminescence is provided for lingual nerve.
Above-mentioned specific shape can be the shape similar to tongue, such as ellipse or sharp circle shape.First medium
The size of substrate, second medium substrate and third dielectric substrate can be determined according to the size of human body tongue, such as be slightly less than tongue
The size of size, first medium substrate, second medium substrate and third dielectric substrate is just the same.By first medium substrate,
Second medium substrate and third dielectric substrate are successively bonded, and obtained electrical stimulation device is the flat sheet with specific shape,
When in use, it can be affixed to tongue when (where first medium substrate while) by be arranged electrod-array 11, makes electro photoluminescence
The electrod-array 11 of device issues stimulation behavior, carries out electro photoluminescence to lingual nerve.
Above-mentioned wireless communication module 13 may include that bluetooth communication, and/or wifi module etc. can receive and dispatch control number
According to the communication module with control instruction.Specifically, controller 15 module 13 can receive other intelligent terminals by wireless communication
The control instruction of transmission controls 17 pulsing signal of pulse generating circuit according to control instruction, by pulse signal transmission to electricity
Pole array 11 makes electrod-array 11 issue stimulation behavior.
Electrod-array 11 can be integrally disposed in first medium base by the electrical stimulation device of lingual nerve provided in this embodiment
On piece, controller 15 and pulse generating circuit 17 are integrally disposed on second medium substrate, and wireless communication module 13 is integrally disposed
On third dielectric substrate, electricity made of such first medium substrate, second medium substrate and third dielectric substrate are successively bonded
The structure of stimulating apparatus has obtained effectively simplifying, and can directly be affixed on relative users tongue, passes through controller 15 therein
The control instruction control pulse generating circuit 17 that wireless communication module 13 receives external equipment generates pulse signal, to make electrode
Array 11 issues the lingual nerve of stimulation behavior stimulation relative users, and relative users can be improved in receiving lingual nerve stimulating course
Comfort level.
In one embodiment, the schematic diagram on the electrical stimulation device two sides of above-mentioned lingual nerve can be refering to what is shown in Fig. 4, electrode
Each electrode of array can be uniformly distributed electrical stimulation device when (when first medium substrate is corresponding), electrical stimulation device
Another side (the corresponding one side of third dielectric substrate) component parts such as wireless communication module can be set.Specific worked
Cheng Zhong, controller module can receive the control instruction that the control equipment such as remote controler or control terminal is sent by wireless communication,
Pulse signal transmission to electrod-array is made into electrod-array according to control instruction control pulse generating circuit pulsing signal
Issuing stimulation behavior stimulates the lingual nerve of the first user.Above-mentioned first user is the user for needing to receive lingual nerve stimulation.
In one embodiment, module receives the Slope Parameters that terminal is sent to controller by wireless communication, according to slope
The pulse parameter of parameter regulation pulse generating circuit;Wherein, Slope Parameters characterize the first user in each statistics of monitoring period of time
The duration variation tendency of particular state is in period;Monitoring period of time receives for the lingual nerve of the first user during electro photoluminescence
Period.
Above-mentioned first user receive for PD patient etc. the user of lingual nerve electro photoluminescence.Above-mentioned particular state
State in which when can characterize the first user movement paresthesia epilepsy for OFF state etc..Above-mentioned OFF state is the movement of PD patient
Paresthesia epilepsy state.Under normal conditions, the first user, which issues, trembles and/or bradykinesia etc. can characterize it and be in particular state
When motor symptoms, it is possible to determine that above-mentioned first user is in particular state.Terminal can pass through correlated condition parameter acquisition devices
It acquires the first user and is in the state parameters such as the duration of particular state in each statistical time range of monitoring period of time, obtain characterization monitoring
The first user is in the Slope Parameters of the duration variation tendency of particular state in period each statistical time range.
Above-mentioned terminal is the statistics duration for acquiring the first user and being in particular state in each statistical time range, according to above-mentioned
Count the smart machine that duration determines the Slope Parameters of characterization duration variation tendency.When above-mentioned monitoring period of time includes multiple statistics
Section.Above-mentioned monitoring period of time can receive according to the first user electro photoluminescence duration characteristics setting, such as can be by above-mentioned monitoring when
Section is set as the periods such as one week or January.Above-mentioned statistical time range can be arranged according to the total duration feature of monitoring period of time, such as
If monitoring period of time is one week, each statistical time range that monitoring period of time includes can be each day in one week, i.e., the 1st day is the 1st
A statistical time range, the 2nd day are the 2nd statistical time range ... ..., and the 7th day is the 7th statistical time range;If monitoring period of time is one
A month, each statistical time range that monitoring period of time includes can be the middle of the month each week, i.e., the 1st week be the 1st statistical time range, the 2nd
2 statistical time ranges ... ... of Zhou Wei, the 4th week is the 4th statistical time range.Specifically, in monitoring period of time, two neighboring statistics
Period be in time it is continuous, i.e., the initial time of each statistical time range respectively previous statistics with corresponding statistical time range when
The end time of section is continuous time, is conducive to carry out continual monitoring to the particular state of the first user, advantageously ensure that
The validity of acquired statistics duration.
As one embodiment, the electrical stimulation device of above-mentioned lingual nerve be can be applied in application environment as shown in Figure 5.
In the application environment, terminal can be the mobile device (MD, Mobil Device) of intelligence, and the side of MD is for acquiring first
The state parameter acquisition device of user, the other side of MD are the electrical stimulation device of lingual nerve.Above-mentioned state parameter acquisition device can
To be worn on the first user, all kinds of state parameters that the first user generates in monitoring period of time are acquired;Electrical stimulation device is placed in
On the tongue of first user, to issue electro photoluminescence behavior to the lingual nerve of the first user.MD respectively with state parameter acquisition device
It is communicatively coupled with electrical stimulation device.The microcontroller of state parameter acquisition device passes through communication module and MD (mobile device)
It is communicated, the components such as 3-D acceleration transducer, heart rate sensor and microphone in state parameter acquisition device can integrate
It is arranged on the bracelet of the first user wearing, the pressure sensor in state parameter acquisition device can be set in the first user foot
On the foot pad at bottom;Above-mentioned 3-D acceleration transducer, heart rate sensor, microphone and/or pressure sensor can acquire first
User is in the state parameter of particular state, and it is digital signal that state parameter, which is sent to analog-digital converter to carry out analog-to-digital conversion,
Afterwards, it is sent to microcontroller, above-mentioned state parameter is sent to MD by communication module, allows MD according to above-mentioned by microcontroller
State parameter determines required Slope Parameters.The communication module (wireless communication module) that Slope Parameters are passed through electrical stimulation device by MD
It is sent to the microcontroller (controller) of electrical stimulation device, produces microcontroller according to the control constant-current source pulse of above-mentioned Slope Parameters
Raw circuit (pulse generating circuit) generates pulse signal, issues electro photoluminescence behavior to the tongue mind of the first user with coordination electrode array
Through carrying out electro photoluminescence.Wherein MD can be held by second user, and second user may include the doctor of the first user and the first user
The user for needing to know the first User Status such as raw, the first user can need to receive the use of lingual nerve electro photoluminescence for PD patient etc.
Family.MD can be, but not limited to be various laptops, smart phone, tablet computer and portable wearable device.
As one embodiment, controller is negative value (value less than 0) recognizing Slope Parameters, and Slope Parameters is exhausted
When being greater than the first adjusting threshold value to value, pulse parameter is turned down;Slope Parameters are being recognized as positive value (value greater than 0), and slope
When the absolute value of parameter is greater than the second adjusting threshold value, pulse parameter is tuned up.
Above-mentioned pulse parameter may include the parameters such as impulse amplitude and/or pulse duty factor.Controller can be by turning down
The mode of impulse amplitude and/or pulse duty factor turns pulse parameter down, by the side for tuning up impulse amplitude and/or pulse duty factor
Formula tunes up pulse parameter.
Above-mentioned first adjusting threshold value and the second adjusting threshold value are respectively positive value.Above-mentioned first, which adjusts threshold value and second, adjusts threshold
Value respectively can be according to the duration characteristics of monitoring period of time and the particular state setting of the first user, for example, if monitoring period of time is 4
Week it can set the first adjusting threshold value to 6 hours, set the second adjusting threshold value to 4 hours.
In the present embodiment, controller can obtain the first user in the corresponding slope of monitoring period of time its particular state from terminal
Parameter, the slope according to duration variation tendency of the first user of characterization in each statistical time range of monitoring period of time in particular state
The electrical stimulation device that parameter carries out electro photoluminescence to the lingual nerve for the first user carries out automatic adjusument, makes the electro photoluminescence of lingual nerve
The stimulation behavior that device issues can be adjusted according to the first user in the particular state feature of monitoring period of time, make to pierce accordingly
Sharp behavior has more specific aim, can simplify the pulse parameter adjustment process of electrical stimulation device, improves and adjusts the real-time of pulse parameter
Property.
As one embodiment, pulse parameter includes impulse amplitude and pulse duty factor;
Controller turns impulse amplitude down first setting ratio;And/or turn pulse duty factor down second setting ratio,
To turn the pulse parameter down;
Impulse amplitude is tuned up the first setting ratio by controller;And/or pulse duty factor is tuned up into the second setting ratio,
To tune up pulse parameter.
Above-mentioned first setting ratio and the second setting ratio respectively can be according to the configuration spies of the electrical stimulation device of lingual nerve
The value of sign setting, the first setting ratio and the second setting ratio may be the same or different, if than only by piercing electricity
The impulse amplitude of excitation device turns the first setting ratio down or turns the pulse duty factor of electrical stimulation device down second setting ratio
It realizes turning down for corresponding pulses parameter, then can set 5% for the first setting ratio and the second setting ratio respectively.
As one embodiment, controller is recognizing Slope Parameters less than or equal to the second adjusting threshold value, and is greater than
Or when adjusting the opposite number of threshold value equal to first, keep pulse parameter constant.
If Slope Parameters, which are less than or equal to second, adjusts threshold value, and is more than or equal to first and adjusts the opposite of threshold value
Number shows that the current pulse parameter of electrical stimulation device is that pulse needed for the lingual nerve of the first user receives corresponding electro photoluminescence is joined
Number, can remain unchanged, without carrying out associated adjustment.
As one embodiment, if setting 5%, b for the first setting ratio and the second setting ratio respectivelyOFFIndicate oblique
Rate parameter, A1 expression the first adjusting threshold value, A2 expression the second adjusting threshold value, symbol " | | " indicate absolute value;Above-mentioned pulse parameter
Adjustment process can be refering to what is shown in Fig. 6, including:
If bOFF< 0 and | bOFF| impulse amplitude is reduced by 5% or pulse duty factor reduction 5% by > A1;
If bOFF> 0 and | bOFF| impulse amplitude is increased by 5% or pulse duty factor increase by 5% by > A2;
If above-mentioned condition is all unsatisfactory for (i.e. bOFF< 0 and | bOFF| > A1 and bOFF> 0 and | bOFF| > A2 both not at
It is vertical), keep pulse parameter constant.
In one embodiment, when terminal obtains statistics of first user in multiple statistical time ranges in particular state
It is long, Slope Parameters are determined according to the statistics duration of each statistical time range.Above-mentioned monitoring period of time includes multiple statistical time ranges.
Specifically, available first user is in the unit duration of particular state at each statistical time range each time, will unite
The sum of each unit duration of timing section is determined as the first user in the statistics duration of corresponding statistical time range.
The present embodiment can draw curve according to the statistics duration of each statistical time range, to determine the first user according to curve
The corresponding Slope Parameters of particular state are in monitoring period of time.Specifically, the corresponding trend parameter of curve in rising trend is big
In 0, for the corresponding trend parameter of curve on a declining curve less than 0, the corresponding trend parameter of fair curve is equal to 0.
As one embodiment, if particular state is OFF state, monitoring period of time is one month, each statistical time range difference
For each week in one month, the curve drawn according to the statistics duration of each statistical time range can be with reference to shown in Fig. 7.
As one embodiment, terminal determines that the process of Slope Parameters can wrap according to the statistics duration of each statistical time range
It includes:
The statistics duration of each statistical time range and period serial number are substituted into slope and determine that formula calculates the first user and monitoring
Period is in the Slope Parameters of particular state;Slope determines that formula includes:
In formula, b indicates Slope Parameters, XiIndicate the period serial number of i-th of statistical time range, YiIndicate i-th of statistical time range
Duration is counted, N indicates the statistical time range number that monitoring period of time includes;Such as coordinate (Xi, Yi) indicate statistical time range XiStatistics duration
For Yi。
The present embodiment can more accurately determine Slope Parameters.
In one embodiment, it refering to what is shown in Fig. 8, the electrical stimulation device of above-mentioned lingual nerve further includes power supply module 18, supplies
Electric module 18 is separately connected wireless communication module 13, controller 15 and pulse generating circuit 17;Power supply module 18 is arranged second
On dielectric substrate.
Above-mentioned power supply module 18 is respectively that wireless communication module 13, controller 15 and pulse generating circuit 17 are powered, and is guaranteed
The work well of the electrical stimulation device of corresponding lingual nerve.
As one embodiment, above-mentioned power supply module is rechargeable battery;
The electrical stimulation device of lingual nerve further includes charge coil;Charge coil connects rechargeable battery;Charge coil setting
On third dielectric substrate.
Above-mentioned power supply module is rechargeable battery, and rechargeable battery connects corresponding charge coil, makes the electricity thorn of lingual nerve
Excitation device can be directly placed on the corresponding recharging base of charge coil and charge, and further ensure the electricity thorn of lingual nerve
Excitation device reuse during convenience.
In one embodiment, the electrical stimulation device of above-mentioned lingual nerve further includes remote controler;Remote controler is by wireless communication
Module is communicated with controller;
Remote controler is used to read the control instruction of user, and by control instruction, module is sent to controller by wireless communication;
Controller controls pulse generating circuit according to control instruction and issues pulse signal.
Above-mentioned control instruction may include pulse generation instruction, and controller can control after receiving above-mentioned control instruction
Pulse generating circuit issues pulse signal.Above-mentioned control instruction can also include pulse parameter, make controller according to above-mentioned pulse
State modulator pulse generating circuit issues corresponding pulse signal.
The present embodiment can be instructed by remote controler input control and be controlled pulse parameter, further improve control
The convenience of the electrical stimulation device of corresponding lingual nerve.
In one embodiment, each electrode of electrod-array is uniformly arranged on first medium substrate.
Specifically, multirow electrode can be set on first medium substrate, the distance between each adjacent rows electrode is equal,
In each row electrode, the interval between each two neighboring electrode is equal, so that each electrode of electrod-array is uniformly arranged on first
On dielectric substrate, guarantee the uniformity of the stimulation issued to lingual nerve movement, and then guarantee corresponding effect of stimulation.
In one embodiment, each dielectric substrate (first medium substrate, second medium substrate and third dielectric substrate)
Schematic diagram can be with refering to what is shown in Fig. 9, in Fig. 9, electrode layer can indicate first medium substrate, and electrode array can be set thereon
Column;Layer of electronic components can indicate second medium substrate, and rechargeable battery, controller and pulse generating circuit can be set thereon
Equal integrated circuit related with same;Communication and charging cable ring layer can indicate third dielectric substrate, and charge coil, wireless can be set thereon
The components such as communication module and communication antenna.Above-mentioned first medium substrate, second medium substrate and third dielectric substrate are successively pasted
It closes, the electrical stimulation device of lingual nerve can be obtained.It, can be by electrode array in the use process of the electrical stimulation device of lingual nerve
Be affixed on the tongue of the first user on one side where column carries out corresponding electro photoluminescence with the tongue to the first user.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.