CN112295107B - Control method of bioelectric waveform for stimulating tongue nerve - Google Patents
Control method of bioelectric waveform for stimulating tongue nerve Download PDFInfo
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- CN112295107B CN112295107B CN202011194733.5A CN202011194733A CN112295107B CN 112295107 B CN112295107 B CN 112295107B CN 202011194733 A CN202011194733 A CN 202011194733A CN 112295107 B CN112295107 B CN 112295107B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
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Abstract
The invention discloses a control method of bioelectric waveforms for stimulating the tongue nerves, which is used for stimulating the tongue nerves, and comprises the steps of measuring the internal humidity of an oral cavity and generating the bioelectric waveforms; the biological current controller is used for measuring and calculating the humidity inside the oral cavity, the biological electric waveform suitable for a patient is generated to stimulate the inside of the oral cavity of the patient in a stimulation mode corresponding to the humidity value according to the humidity parameter obtained by measuring the flexible interdigital electrode and the humidity value obtained by calculating the main controller according to a calculation formula, and the effects of measuring the humidity inside the oral cavity and forming the biological electric waveform are achieved.
Description
Technical Field
The invention relates to the technical field of bioelectric current generation, in particular to a control method of bioelectric waveforms for stimulating tongue nerves.
Background
The bioelectric current is a source for realizing the stimulation of the tongue nerve, and the design of bioelectric modes, intensity and frequency suitable for patients is realized, namely the design of bioelectric waveforms for stimulating the tongue nerve is undoubtedly the key factor for realizing the nerve stimulation device on the tongue.
Various medical electrical stimulation devices are available at home and abroad, such as cardiac pacemakers, artificial cochlea, cranial nerve stimulators, muscle nerve stimulators, acupuncture point stimulators and the like; the devices stimulate different nervous systems in a voltage or current mode and in different voltage or current waveforms through different installation positions so as to realize a stimulation function; but different from the stimulation of the tongue nerve, the optimal stimulation point of the tongue nerve is positioned at the mucosa in the oral cavity, the moving position of the tongue nerve is shallow, and the difference from the installation electricity of the medical electrical stimulation equipment is large; the characteristics of the lingual nerve are different from those of the muscular nerve, the auditory nerve, the tibial nerve and the like, and thus, it is not appropriate to directly use the bioelectric waveform of other medical electrical stimulation apparatuses for the lingual nerve stimulation apparatus. Moreover, the other medical electrical stimulation devices also have unique bioelectric waveforms.
The design of the bioelectric waveform of the nerve stimulation device is a long-period work, and the essential basic condition is to be capable of measuring the humidity in the oral cavity of a patient; at present, common temperature and humidity detection is difficult to use in the oral cavity of a patient; the prior art is a method for measuring oral cavity humidity by using an air blowing pipe and a humidity sensor, as shown in figure 2, but the use mode is slightly complicated and the real-time performance is insufficient.
Disclosure of Invention
Aiming at the technical problems of difficulty in oral humidity measurement and bioelectrical waveform generation, the invention provides a control method of a bioelectrical waveform for stimulating the tongue nerve.
In order to achieve the purpose, the invention is realized by the following technical scheme:
a method of controlling a bioelectric waveform for stimulating a tongue nerve, comprising: a master controller, a device for stimulating the tongue nerve,
the method for controlling the bioelectrical waveform comprises the following steps: the method comprises the following steps: parameter acquisition, including: the output current I and the voltage U of the programmable constant current source and the time t for fully charging the capacitor are obtained;
step two: the main controller calculates according to a first preset formula to obtain a first capacitance value;
step three: the main controller calculates the size of the first capacitance value and the size of a preset capacitance value according to a preset algorithm to obtain a capacitance difference value;
step four: the main controller brings the capacitance difference value into a second preset formula to calculate to obtain a humidity difference value;
step five: at least one stimulation mode is arranged in the main controller, and the main controller selects the stimulation mode matched with the humidity difference value according to the humidity difference value;
step six: the main controller is connected with a programmable constant current source in a control mode, and the programmable constant current source outputs bioelectric waveforms according to a preset stimulation mode.
Further, the parameter acquisition is to carry out charging detection on a capacitor formed by the pair of flexible interdigital electrodes through a programmable constant current source, and the parameter acquisition comprises the following specific steps:
one end of the flexible interdigital electrode is in contact with the measuring point, the main controller controls the programmable constant current source to output current and voltage, the current output by the programmable constant current source is I, the voltage output by the programmable constant current source is U, and the main controller measures the time t for the programmable constant current source to fully charge the capacitor.
Further, the first predetermined formula is
The main controller brings the parameters into a first preset formula to calculate to obtain a first capacitance value; c is a first capacitance value, I is the current output by the programmable constant current source, U is the voltage output by the programmable constant current source, and t is the time when the main controller detects that the capacitor is fully charged by the programmable constant current source;
further, the main controller performs subtraction operation on the first capacitance value and a preset capacitance value to obtain a capacitance difference value.
Further, the second preset formula is Δ M = K × Δ C, and the master controller brings the capacitance difference value into the second preset formula to calculate to obtain a humidity difference value; in the formula, Δ M is a humidity difference value, K is a humidity coefficient, and Δ C is a capacitance difference value.
Further, the main controller is provided with a strong stimulation mode, a middle stimulation mode and a weak stimulation mode; a first humidity difference value, a second humidity difference value and a third humidity difference value are preset in the main controller; different humidity difference values preset in the main controller correspond to different stimulation modes; when the humidity difference value in the oral cavity is a first humidity difference value, the main controller controls the programmable constant current source to execute a strong stimulation mode; when the humidity difference value in the oral cavity is a second humidity difference value, the main controller controls the programmable constant current source to execute a middle stimulation mode; and when the humidity difference value in the oral cavity is a third humidity difference value, the main controller controls the programmable constant current source to execute a weak stimulation mode.
Further, the strong stimulation pattern includes 30 pulse groups, each pulse group includes 25 pulses, each pulse has a stimulation time of 5 seconds, and a time interval between adjacent pulse groups is 2 seconds.
Further, the middle stimulation mode includes 20 pulse groups, each pulse group includes 25 pulses, each pulse has a stimulation time of 5 seconds, and a time interval between adjacent pulse groups is 15 seconds.
Further, the weak stimulation pattern includes a set of 15 pulses, each pulse having a stimulation time of 3 seconds and a time interval of 60 seconds between adjacent pulse sets.
Compared with the prior art, the invention has the following advantages:
the invention can measure the humidity in the oral cavity, and generate the stimulation electric waveform suitable for a patient through the processing of the controller so as to achieve the purpose of self-adaptive stimulation.
Drawings
FIG. 1 is a schematic diagram of the operation of the present embodiment;
fig. 2 is a schematic structural diagram of the prior art.
Reference numerals: 1-a master controller; 2-a programmable constant current source; 3-stimulation electrode.
Detailed Description
The present invention is described in further detail below with reference to fig. 1-2.
A method of controlling a bioelectric waveform for stimulating a tongue nerve, comprising: a master controller, a device for stimulating the tongue nerve,
the method for controlling the bioelectrical waveform comprises the following steps:
the method comprises the following steps: parameter acquisition, including: the output current I and the voltage U of the programmable constant current source and the time t for fully charging the capacitor are obtained;
step two: the main controller calculates a first capacitance value according to a first preset formula;
step three: the main controller calculates the size of the first capacitance value and the size of a preset capacitance value according to a preset algorithm to obtain a capacitance difference value;
step four: the main controller brings the capacitance difference value into a second preset formula to calculate to obtain a humidity difference value;
step five: at least one stimulation mode is arranged in the main controller, and the main controller selects the stimulation mode matched with the humidity difference value according to the humidity difference value;
step six: the main controller is connected with a programmable constant current source in a control mode, and the programmable constant current source outputs bioelectric waveforms according to a preset stimulation mode.
Optionally, the parameter acquisition is to perform charging detection on a capacitor formed by a pair of flexible interdigital electrodes through a programmable constant current source, and the parameter acquisition specifically includes the following steps:
one end of the flexible interdigital electrode is in contact with the measuring point, the main controller controls the programmable constant current source to output current and voltage, the current output by the programmable constant current source is I, the voltage output by the programmable constant current source is U, and the main controller measures the time t for the programmable constant current source to fully charge the capacitor.
The device for stimulating the tongue nerve comprises a flexible interdigital electrode 3 and a biological current controller, wherein the biological current controller comprises a main controller and a programmable constant current source; the main controller 1 runs a control program and a preset algorithm, and the flexible interdigital electrode 3 is matched with the main controller to acquire humidity data in the oral cavity; the programmable constant current source 2 is connected with the flexible interdigital electrode 3; the flexible interdigital electrode 3 measures the humidity inside the oral cavity; one end of each flexible interdigital electrode 3 is in contact with a measuring point, a layer of humidity-sensitive material is covered on the surfaces of the flexible interdigital electrodes 3 to serve as a dielectric medium, capacitance is generated by transverse electromagnetic coupling between the coplanar electrodes, and the capacitance value of the capacitance formed by the flexible interdigital electrodes 3 can be changed due to the change of humidity inside the oral cavity.
The dielectric medium on the flexible interdigital electrode 3 can change the dielectric constant due to the adsorption or desorption of water molecules, so that the capacitance on the flexible interdigital electrode 3 is changed; the programmable constant current source 2 charges a capacitor of the flexible interdigital electrode 3, the output voltage, the capacitor charging time and the output current are used as feedback parameters to be sent to the main controller 1, and the main controller 1 calculates the feedback parameters according to a formula to obtain humidity data in the oral cavity; the main controller 1 is used for programming and controlling the programmable constant current source 2 to generate tongue nerve stimulation bioelectricity waveforms adapting to the patient, and the main controller 1 is used for controlling the output current of the programmable constant current source 2 to be controllable.
Optionally, the first predetermined formula is
In the formula, delta M is a humidity difference value, K is a humidity coefficient, and delta C is a capacitance difference value; the main controller brings the parameters into a first preset formula to calculate to obtain a first capacitance value.
Optionally, the main controller performs subtraction on the first capacitance value and a preset capacitance value to obtain a capacitance difference value.
Optionally, the second preset formula is Δ M = K × Δ C, the master controller brings the capacitance difference value into the second preset formula to calculate to obtain a humidity difference value, where Δ M is the humidity difference value, K is the humidity coefficient, and Δ C is the capacitance difference value.
The main controller 1 calculates the collected humidity data; the capacitor formed by the flexible interdigital electrode 3 is charged through a programmable constant current source, and the current output by the programmable constant current source 2 is I; the voltage output by the programmable constant current source 2 is U; the main controller 1 measures the time t for the programmable constant current source 2 to fill the capacitor in a timing mode; substituting the parameters into a first preset formula to calculate to obtain a first capacitance value, wherein the first preset formula is
C is a first capacitance value, I is the current output by the programmable constant current source, U is the voltage output by the programmable constant current source, and t is the time when the main controller detects that the capacitor is fully charged by the programmable constant current source; then, subtracting the first preset capacitance value from the preset capacitance value to obtain a capacitance difference value delta C, wherein delta C is the capacitance difference value; the capacitance difference value deltaC is substituted into a second preset formula to obtain a humidity difference value, wherein the second preset formula is that deltaM = K deltaC, K is a humidity coefficient, and deltaC is the capacitance difference value, the main controller 1 further calculates a humidity integral value of each period, and the calculation formula of the humidity integral value is K sigma deltaC; where Δ C is the capacitance difference and K is the humidity coefficient.
Optionally, the main controller is provided with a strong stimulation mode, a medium stimulation mode and a weak stimulation mode; a first humidity difference value, a second humidity difference value and a third humidity difference value are preset in the main controller; different humidity difference values preset in the main controller correspond to different stimulation modes; the first humidity difference corresponds to a strong stimulation mode, the second humidity difference corresponds to a medium stimulation mode, and the third humidity difference corresponds to a weak stimulation mode.
Optionally, the strong stimulation mode includes 30 pulse groups, each pulse group includes 25 pulses, the stimulation time of each pulse is 5 seconds, and the time interval between adjacent pulse groups is 2 seconds.
Optionally, the middle stimulation mode includes 20 pulse groups, each pulse group includes 25 pulses, the stimulation time of each pulse is 5 seconds, and the time interval between adjacent pulse groups is 15 seconds.
Optionally, the weak stimulation pattern comprises a set of 15 pulses, each pulse having a stimulation time of 3 seconds and a time interval of 60 seconds between adjacent pulse sets.
The method for generating the bioelectrical waveform comprises the following steps: 3 stimulation modes are preset in the main controller 1, and three stimulation modes matched with the humidity difference delta M are preset in the main controller 1; the main controller 1 controls the programmable constant current source 2 to send out pulses; wherein, when the humidity difference is 1-4, the strong stimulation mode is selected, and when the humidity difference is 4-7, the medium stimulation mode is selected; the weak stimulation mode is selected when the humidity difference is 7-10. Wherein the strong stimulation mode comprises 30 pulse groups, each pulse group comprises 25 pulses, and the stimulation time of each pulse is 5 seconds; the middle stimulation mode comprises 20 pulse groups, each pulse group comprises 25 pulses, the stimulation time of each pulse is 5 seconds, and the time interval between every two adjacent pulse groups is 15 seconds; the stimulation mode comprises a continuous pulse group, the pulse group of the weak stimulation mode consists of 15 pulses, the stimulation time of pulse current is 3 seconds, the interval time between the pulse groups is 60 seconds, and the interval time between the pulse groups is 2 seconds; the programmable constant current source 2 has a pulse current intensity of 10 microamperes in an initial state, a pulse width of 1 millisecond and a pulse period of 200 milliseconds.
The present embodiment is only for explaining the invention, and it is not limited to the present invention, and those skilled in the art can make modifications to the present embodiment as necessary without inventive contribution after reading the present specification, but all of them are protected by patent law within the scope of the present invention.
Claims (5)
1. A method of controlling a bioelectric waveform for stimulating a tongue nerve, comprising: a master controller, a device for stimulating the tongue nerve, characterized by:
the bioelectrical waveform control method comprises the following steps:
the method comprises the following steps: acquiring parameters: the method comprises the following steps of (1) carrying out charging detection on a capacitor formed by a pair of flexible interdigital electrodes through a programmable constant current source, wherein the parameters comprise: the output current I and the voltage U of the programmable constant current source and the time t for fully charging the capacitor are obtained;
step two: the main controller brings the parameters into a first preset formula to calculate to obtain a first capacitance value;
step three: the main controller performs subtraction operation on the first capacitance value and a preset capacitance value to obtain a capacitance difference value delta C;
step four: the main controller brings the capacitance difference value into a second preset formula to calculate to obtain a humidity difference value;
step five: at least one stimulation mode is arranged in the main controller, and the main controller selects the stimulation mode matched with the humidity difference value according to the humidity difference value;
step six: the main controller is connected with a programmable constant current source in a control mode, and the programmable constant current source outputs a bioelectric waveform according to a preset stimulation mode;
the specific steps of parameter acquisition are as follows: one end of the flexible interdigital electrode is in contact with a measuring point, and the main controller controls the programmable constant current source to output current and voltage;
the first preset formula is as follows:
c is a first capacitance value, I is the current output by the programmable constant current source, U is the voltage output by the programmable constant current source, and t is the time when the main controller detects that the capacitor is fully charged by the programmable constant current source;
the second preset formula is as follows:
ΔM＝K*ΔC
in the formula, Δ M is a humidity difference value, K is a humidity coefficient, and Δ C is a capacitance difference value.
2. The control method of bioelectrical waveforms for stimulating the tongue nerve according to claim 1, characterized in that: the main controller is provided with a strong stimulation mode, a middle stimulation mode and a weak stimulation mode; a first humidity difference value, a second humidity difference value and a third humidity difference value are preset in the main controller; different humidity difference values preset in the main controller correspond to different stimulation modes; when the humidity difference value in the oral cavity is a first humidity difference value, the main controller controls the programmable constant current source to execute a strong stimulation mode; when the humidity difference value in the oral cavity is a second humidity difference value, the main controller controls the programmable constant current source to execute a middle stimulation mode; and when the humidity difference value in the oral cavity is a third humidity difference value, the main controller controls the programmable constant current source to execute a weak stimulation mode.
3. The control method of bioelectrical waveforms for stimulating the tongue nerve according to claim 2, characterized in that: the strong stimulation pattern comprises 30 pulse groups, each pulse group comprises 25 pulses, the stimulation time of each pulse is 5 seconds, and the time interval between adjacent pulse groups is 2 seconds.
4. The control method of bioelectrical waveforms for stimulating the tongue nerve according to claim 2, characterized in that: the medium stimulation mode includes 20 pulse groups, each pulse group includes 25 pulses, the stimulation time of each pulse is 5 seconds, and the time interval between the adjacent pulse groups is 15 seconds.
5. The control method of bioelectrical waveforms for stimulating the tongue nerve according to claim 2, characterized in that: the weak stimulation pattern included a set of 15 pulses with a stimulation time of 3 seconds per pulse and a time interval of 60 seconds between adjacent pulse sets.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2015047363A (en) * | 2013-09-02 | 2015-03-16 | テルモ株式会社 | Electrostimulator |
| CN107019495A (en) * | 2017-03-13 | 2017-08-08 | 北京航空航天大学 | Apnea detection and prior-warning device and method based on smart mobile phone and the mounted respiration transducer of nose |
| CN109865194A (en) * | 2019-01-28 | 2019-06-11 | 廖旺才 | The electrical stimulation device of lingual nerve |
| CN209269665U (en) * | 2018-07-23 | 2019-08-20 | 西南医科大学附属医院 | A kind of oral cavity humidity detector |
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- 2020-10-30 CN CN202011194733.5A patent/CN112295107B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015047363A (en) * | 2013-09-02 | 2015-03-16 | テルモ株式会社 | Electrostimulator |
| CN107019495A (en) * | 2017-03-13 | 2017-08-08 | 北京航空航天大学 | Apnea detection and prior-warning device and method based on smart mobile phone and the mounted respiration transducer of nose |
| CN209269665U (en) * | 2018-07-23 | 2019-08-20 | 西南医科大学附属医院 | A kind of oral cavity humidity detector |
| CN109865194A (en) * | 2019-01-28 | 2019-06-11 | 廖旺才 | The electrical stimulation device of lingual nerve |
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| Translational Research in Anatomy;Sanaa Aljamani;《Translational Research in Anatomy》;20200619;全文 * |
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