CN109832625A - A kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity - Google Patents
A kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity Download PDFInfo
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- CN109832625A CN109832625A CN201810946956.9A CN201810946956A CN109832625A CN 109832625 A CN109832625 A CN 109832625A CN 201810946956 A CN201810946956 A CN 201810946956A CN 109832625 A CN109832625 A CN 109832625A
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- oyster
- powder
- rhizoma polygonati
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- 241000219780 Pueraria Species 0.000 claims abstract description 30
- 238000000034 method Methods 0.000 claims abstract description 22
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/50—Molluscs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/65—Addition of, or treatment with, microorganisms or enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/70—Comminuted, e.g. emulsified, fish products; Processed products therefrom such as pastes, reformed or compressed products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention discloses a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, according to parts by weight includes 20~60 parts of pueraria root powder, 10~40 parts of D-sorbite, 5~40 parts of maltodextrin, 5~30 parts of rhizoma polygonati powder, 5~20 parts of ostreae testa pulverata, 0.1~3 part of magnesium stearate.Product is crushed through feedstock processing, cryogenic high pressure extruding, ostreae testa pulverata preparation, mixing, and the techniques such as tabletting obtain.The present invention uses low temperature expanding technology, keeps nutritional ingredient to greatest extent, promotes breaking-wall cell, active principle is made to be easier to absorb.This product experiments verify that, have and alleviate physical fatigue, the effect of strengthen immunity.
Description
Technical field
The present invention relates to technical field of health care food, and in particular to a kind of composition for alleviating physical fatigue strengthen immunity
And preparation method thereof.
Background technique
Fatigue is a kind of early warning reaction of physiological of human body, is looked like that is fatigue occur is exactly to remind people in time
It rests.Because the short time is tired, physical strength can be enable to restore by the rest of short time.But adhere to super negative for a long time
Work to lotus, in addition often staying up late, diet not timing will make the accumulation of fatigue, occur last -- overwork.With modern society
It can compete more and more fierce, pressure is increasing, and rhythm of life is constantly accelerated, and operating pressure leads to greatly over fatigue.Fatigue is led
Viscera, qi and blood dysequilibrium are caused, essence, gas, mind are impaired.In addition abnormal life and eating habit, cause immunity by
It gradually reduces, people's body is often in sub-health state.Allegro life makes people have no time the unsound body for scrupling oneself
Body.Meanwhile disease symptom of overworking is low fever, cold, swollen lymph node, throat swelling and pain, courbature, arthralgia etc..Appear as trouble
The same merging symptom of flu.
Summary of the invention
An object of the present invention is to provide a kind of composition for alleviating physical fatigue strengthen immunity.
The second object of the present invention is to provide a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity.
These and other objects of the invention will be come further elucidated above by the following detailed description and explanation.
A kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, specifically includes that according to parts by weight
20~60 parts of pueraria root powder, 10~40 parts of D-sorbite
5~40 parts of maltodextrin, 5~30 parts of rhizoma polygonati powder
5~20 parts of ostreae testa pulverata, 0.1~3 part of magnesium stearate
Further, a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, leads according to parts by weight
Include:
30~50 parts of pueraria root powder, 15~30 parts of D-sorbite
10~30 parts of maltodextrin, 10~20 parts of rhizoma polygonati powder
8~15 parts of ostreae testa pulverata, 1~2.5 part of magnesium stearate
It is preferred that a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, according to parts by weight mainly
Include:
40 parts of pueraria root powder, 20 parts of D-sorbite
15 parts of maltodextrin, 13 parts of rhizoma polygonati powder
10 parts of ostreae testa pulverata, 2 parts of magnesium stearate
A kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, oyster powder preparation technique are as follows:
(1) it is crushed: fresh oyster being put into crusher and is crushed；
(2) it cleans: broken oyster being put into service sink, is carried out clearly with 0.1mol/L~0.5mol/L NaOH solution
12~18h is washed and impregnated, is then washed till neutrality with clear water；
(3) it crushes mashing: broken oyster being put into colloid mill and is further crushed, purified water is added, is configured to expect
Liquor ratio is 1: 1~1: 3, makes oyster at slurry condition；
(4) it digests: being digested using composite hydrolytic enzyme, composite hydrolytic enzyme is acid protease, and papain is neutral
Protease, one or more of bromelain, additive amount are 0.5 ‰~the 1.0 ‰ of oyster quality, and hydrolysis temperature control exists
45 DEG C~60 DEG C, enzymolysis time is controlled in 1h~4h, solution ph 4.0~7.0；
(5) enzyme deactivation: after enzymatic hydrolysis, the temperature of enzymatic vessel is increased to 70 DEG C~90 DEG C, maintains 30min~60min；
(6) separation and purification: the feed liquid after enzyme deactivation is released from enzymatic vessel, is once filtered by plate filter,
It is filtered using film and carries out secondary filter, by nanofiltration membrane desalination, obtain purification oyster hydrolyzate；
(7) be concentrated: oyster hydrolyzate controls vacuum degree in 0.5Mpa~1.0Mpa, when quality is dense by negative pressure inspissator
Degree stops concentration 40%~50%；
(8) it sterilizes: using high-temperature short-time sterilization, temperature is controlled at 110 DEG C~130 DEG C, is maintained 5s~10s, is turned after sterilizing
Enter intermediate storage tank；
(9) it is spray-dried: oyster hydrolyzate in intermediate storage tank being squeezed into spray drying tower through pump and is spray-dried, into
At 160 DEG C~200 DEG C, outlet temperature carries out receipts powder at 90 DEG C~100 DEG C for mouth temperature control.
A kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, which is characterized in that pueraria root powder, rhizoma polygonati
Powder uses cryogenic high pressure bulking process, the specific process is as follows:
(1) maca, rhizoma polygonati are respectively washed completely, clean, dry, crush；
(2) it is packed into Bulking tank, air-flow is blown by compressor, temperature, which is stepped up, in tank reaches 85~105 DEG C, in tank
Formation certain pressure be 0.8~1.5Mpa, the time be 20~40s after release stress；
A kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, specific preparation process are as follows:
(1) feedstock processing: maca, rhizoma polygonati cleaning clean, dry, crush,
(2) low temperature expanding: it is packed into Bulking tank, air-flow is blown by compressor, temperature, which is stepped up, in tank reaches 85~105
DEG C, in tank formed certain pressure be 0.8~1.5Mpa, the time be 20~40s after release stress；
(3) it crushes: pueraria root powder, the rhizoma polygonati powder after extruding is crushed again, and cross 60 meshes；
(4) ostreae testa pulverata prepare: fresh oyster meat is cleaned, be crushed, crush mashing, enzymatic hydrolysis, enzyme deactivation, separation and purification, concentration,
The techniques such as sterilizing, spray drying are made；
(5) it mixes: weighing ostreae testa pulverata, D-sorbite, maltodextrin, magnesium stearate etc. in three-dimensional mixer according to formula ratio
In mixed, incorporation time 30min~60min；
(6) tabletting: after mixing, tabletting is carried out with tablet press machine.
Design principle of the present invention
Maca: for Cruciferae Lepidium plant, originating in 3500~4500 meters of height above sea level of South America andes region, existing
In the ecotope Puno and Peru the southeastern city of Puno being mainly distributed in the middle part of Peru.Maca South America edible history
Have more than 5800 years, be conventionally used to strengthening body, improve fertility, improves sexual function, antidepression, anti-anemia action etc..From 20th century
Some tradition at the initial stage sixties to the eighties, the research gradually systematization about maca botany and medical value, maca are made
With the scientific validation of Germany and North American Plant researcher is obtained, especially after the eighties, FAO (Food and Agriculture Organization of the United Nation) (FAO) is built
Plantation of the countries in the world popularization to maca is discussed, chemical component identification, active constituent separation and its pharmacological action of maca etc. obtain
Further discussion, wherein maca improves fertility, improves sexual function, anticancer, anti-leukocythemia, treatment climacteric syndrome etc.
Effect becomes current research hotspot.Iron of the maca containing higher amount, the ingredients such as protein, amino acid, minerals zinc, taurine,
Can be obviously to antifatigue, enhancing muscular endurance, resistance exercise induced fatigue helps firm immune system, promotes body's resistance to disease, can
To regain one's strength of body rapidly, fatigue is eliminated, is regained one's vigor.In addition, the Ministry of Public Health's No. 13 bulletin macas in 2011 are approved for new food
Raw material carry out using.
Rhizoma polygonati: for HUANGJING ZANYU CAPSULE, rhizome it is horizontal walk, cylindric, tubercle expands.Impeller generator, stockless.Medicinal plant, it is mild-natured,
It is sweet in flavor, returns spleen, lung, kidney channel, with tonifying spleen, the effect of moistening lung and producing body fluid.Meanwhile rhizoma polygonati has resisting pathogenic microbes effect, to kidney
Excessively high blood glucose caused by upper parathyrine is in significant inhibiting effect, and antifatigue effect, anti-aging, anastalsis, resists antioxidation
The effects of viral.
Oyster: also known as raw oyster, it is bivalve, is distributed in each ocean stretch of coastal water in temperate zone and the torrid zone.Cold nature,
Taste is at returning liver, gallbladder, kidney channel.Oyster glycogen rich in, protein, amino acid, microelement and vitamin etc..Oyster tool
There is the effects of strengthen immunity, anti-oxidant, antifatigue, antiviral, hypoglycemic, protect liver, is antibacterial, antitumor.Contain in oyster meat
There are many amino acid.In addition, contain taurine in oyster meat, polysaccharide isoreactivity substance.
Maca is new resource food, there is the function of nourishing and fit keeping function to human body, can be tonified Qi of the kidney, hard bone salubrity, antifatigue,
Enhance physical strength, improves immune function.Rhizoma polygonati has tonifying Qi kidney-nourishing, and the functions such as invigorating the spleen moistening lung can be used for treating weakness of the spleen and the stomach, dry
Deficiency of food, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, the diseases such as Heat Diabetes.In addition, rhizoma polygonati also has the effects of antifatigue, strengthen immunity.It is male
Oyster has the effects that strengthen immunity, anti-oxidant, antifatigue, antiviral, hypoglycemic, protects liver, is antibacterial, antitumor.Oyster is cold
Property neutralized the warm nature of maca, this product integrally belongs to levelling product, and people takes for a long time to be unlikely to get angry while help.
In the prior art, pueraria root powder, rhizoma polygonati powder, ostreae testa pulverata, it is single or any two are respectively combined with other products
To product have a sale, but the present invention measures combination using this three according to the ratio, and by low temperature expanding technology progress raw material at
Reason, compared with traditional raw material processing, whole curative effect is obviously improved.
The beneficial effects of the present invention are: the present invention is a kind of composition for alleviating physical fatigue strengthen immunity, through low temperature
Puffing technique keeps raw material cell wall broken, and raw material is promoted more preferably to absorb, product experiments verify that, have and alleviate physical fatigue, increase
The effect of strong immunity, and compared with similar products, better effect.
Situation is embodied
Present invention will be further explained below with reference to specific examples.These embodiments are interpreted as being merely to illustrate this hair
It is bright rather than limit the scope of the invention.After having read the content of the invention recorded, those skilled in the art can
To make various changes or modifications to the present invention, these equivalence changes and modification equally fall into model defined by the claims in the present invention
It encloses.
Embodiment 1: anti-fatigue effect experiment
1. materials and methods
1.1 experimental animals: SPF grades of healthy kunming mices, male.By Beijing Vital River Experimental Animals Technology Co., Ltd.
It provides, experimental animal production licence: SCXK (capital) 2006-0009.Feeding environment be barrier grade, 23 DEG C of experimental situation temperature~
24 DEG C, humidity 54%~58%.
1.2 experimental methods: being divided into 5 groups for male Kunming strain mice, every group 10, respectively low dose group, middle dose group,
High dose group, blank control group and positive controls.Low dose group, middle dose group, high dose group tested material be 0.4,0.8,
Sample prepared by 1.2g/kg embodiment 4, positive controls tested material are the red ox drinks of 1.2g/kg, and blank group is consubstantiality
Product physiological saline, every 10g weight give tested material 0.2mL, after taking administration by gavage, continuous gavage that 30d is administered, measure the power of mouse
Exhaust the variation of the indexs such as swimming time, blood urea nitrogen, hepatic glycogen content.
Swimming with a load attached to the body experiment: by 5% galvanized wire of mouse tail weight bearing mouse weight, it is placed in 40cm × 60cm × pond 36cm
Went swimming, depth of water 30cm, 30 DEG C ± 0.5 DEG C of water temperature, 10, every pond mouse exhausts (mouse to power since swimming with stopwatch record
10s cannot still emerge after sinking) time as the mouse exhausted swimming time.Hepatic glycogen, the inspection of serum urea nitrogen content
It surveys experiment: successive administration 30 days, after last gives tested material 30min, mouse being put in depth of water 30cm, 30 DEG C ± 0.5 DEG C of water temperature
Water went swimming, pond 40cm × 60cm × 36cm, pluck eyeball after mouse not swimming with a load attached to the body 90min, rest 60min by every group 10
Blood is taken, with kit measurement serum urea nitrogen content.Meanwhile mouse liver is taken out, 200mg is accurately weighed, is surveyed using anthrone method
Determine mouse hepatic glycogen content.
1.3 Testing index: swimming time, blood urea nitrogen, hepatic glycogen content.
1.4 data statistics: data statistic analysis is carried out to testing result using SPSS software.
2. experimental result
Influence of 2.1 samples to swimming time, blood urea nitrogen, hepatic glycogen content.
Influence of 1 sample of table to mouse swimming time, serum urea nitrogen, hepatic glycogen content
" * " indicates that p < 0.05 compared with the control group, " * * " indicate p < 0.01 compared with the control group.
As can be seen from Table 1, compared with blank group, the low, middle and high dose groups mouse exhausted swimming time significantly extends (p
< 0.05), positive controls are almost unchanged；Hepatic glycogen content obviously increases (p < 0.01), and positive controls are almost without change
Change；Urea nitrogen content is significantly lower than blank group (p < 0.01), and positive controls are almost unchanged.As can be seen from the above results,
Maca instant tea of the present invention can generate positive shadow to mouse swimming time, hepatic glycogen, serum urea nitrogen content etc. in movement
It rings, and effect is substantially better than control sample.
3. conclusion
Experimental result as it can be seen that low, middle and high dose groups compared to the blank group compared with mouse swimming time is obviously prolonged, and is mentioned
High liver glycogen reserves amount, hence it is evident that reduce serum urea nitrogen content, illustrate of the present invention with anti-fatigue effect.
Embodiment 2: immunity function experiment is improved
1. materials and methods
1.1 experimental animal
SPF grades of healthy kunming mices, male.It is provided by Beijing Vital River Experimental Animals Technology Co., Ltd., experiment is dynamic
Object production licence: SCXK (capital) 2006-0009.Feeding environment be barrier grade, 23 DEG C~24 DEG C of experimental situation temperature, humidity
54%~58%.
1.2 experimental method
1.2.1 animal packet
Male Kunming strain mice is divided into 5 groups, every group 10, respectively low dose group, middle dose group, high dose group, sky
White control group and positive controls.Low dose group, middle dose group, high dose group tested material are 0.4,0.8,1.2g/kg embodiment 4
The sample of preparation, positive controls tested material are that the Amway Echinacea purpurea of 1.2g/kg is healthy and strong piece, and blank group is same volume physiology salt
Water, every 10g weight give tested material 0.2mL, after taking administration by gavage, continuous gavage that 30d is administered.
1.2.2 experimental method
According to the Ministry of Public Health " health food is examined and assessment technique specification " (2003 editions), lymphopoiesis ability OD is carried out
(phagocytic index a) carries out functional evaluation, test for difference, swelling degree of the paw, half hemolytic value (HC50) and mouse carbonic clearance test
It the results are shown in Table 2.
Influence overall assessment table of the health food of the present invention of table 2 to immune function of mice
" * " indicates that p < 0.05 compared with the control group, " * * " indicate p < 0.01 compared with the control group.
The results showed that the health care product of the present invention of each dosage of orally administration mouse 30 days, middle dose group can significantly improve
Ability (p < 0.01), mouse swelling degree of the paw (p < 0.05) and the lymphopoiesis of one macrophage carbonic clearance of mouse monokaryon
Ability (p < 0.05)；The ability (p < 0.01) of one macrophage carbonic clearance of mouse monokaryon, mouse can be remarkably reinforced in high dose group
Swelling degree of the paw (p < 0.01) and lymphopoiesis ability (p < 0.01) and half hemolytic value (the p < for improving mouse
0.01), compared with positive controls, no conspicuousness (p > 0.05).Experiment shows that health care product of the present invention has strengthen immunity
Healthcare function.
3. conclusion
Experimental result as it can be seen that middle and high dosage group compared to the blank group compared with, mouse phagocytic index (a), swelling degree of the paw, leaching
Bar ability of cell proliferation, half hemolytic value etc. all have significant change, and illustrate of the present invention there is strengthen immunity.
Embodiment 3: bulking process influences to study on product
It is yellow to pueraria root powder, rhizoma polygonati powder, ostreae testa pulverata, maca+rhizoma polygonati+ostreae testa pulverata, extruding maca+extruding by 1 method of embodiment
The groups such as essence+ostreae testa pulverata are tested, and test result is as follows:
Influence of the 3 different process various combination product of table to mouse anti-reflecting fatigue
As shown in Table 3, single raw material pueraria root powder, rhizoma polygonati powder, ostreae testa pulverata is all improved mouse swimming time, and glycogen is original
It is promoted；Serum urea nitrogen content decreases.Illustrate that pueraria root powder, rhizoma polygonati powder, ostreae testa pulverata all have the function of relieving fatigue.This
Outside, pueraria root powder+rhizoma polygonati powder+oyster compound powder overall effect is better than single raw material.Meanwhile pueraria root powder+Huang of after the swelling
Fine powder+oyster compound powder overall effect is better than non-extruding pueraria root powder+rhizoma polygonati powder+oyster compound powder.Through experiments, it was found that adjusting
Pueraria root powder+rhizoma polygonati powder+ostreae testa pulverata adding proportion after whole extruding, will affect and directly affect product overall effect.
Embodiment 4
Product formula amount: 42 parts of pueraria root powder, 18 parts of D-sorbite, 15 parts of maltodextrin, 14 parts of rhizoma polygonati powder, 8 parts of ostreae testa pulverata,
3 parts of magnesium stearate.
The preparation method of ostreae testa pulverata:
(1) it is crushed: fresh oyster being put into crusher and is crushed；
(2) it cleans: broken oyster being put into service sink, 12h is cleaned and impregnated with 0.2mol/L NaOH solution,
Then neutrality is washed till with clear water；
(3) it crushes mashing: broken oyster being put into colloid mill and is further crushed, purified water is added, is configured to expect
Liquor ratio is 1: 1, makes oyster at slurry condition；
(4) it digests: being digested using composite hydrolytic enzyme, acid protease, neutral proteinase, one in bromelain
Kind is several, and additive amount is the 0.5 ‰ of oyster quality, and hydrolysis temperature is controlled at 45 DEG C, and enzymolysis time is in 1.5h, solution ph control
System is 4.0；
(5) enzyme deactivation: after enzymatic hydrolysis, the temperature of enzymatic vessel is increased to 80 DEG C, maintains 30min；
(6) separation and purification: the feed liquid after enzyme deactivation is released from enzymatic vessel, is once filtered by plate filter,
It is filtered using film and carries out secondary filter, by nanofiltration membrane desalination, obtain purification oyster hydrolyzate；
(7) be concentrated: oyster hydrolyzate is by negative pressure inspissator, and control vacuum degree is in 0.5Mpa, when mass concentration is 40%,
Stop concentration；
(8) it sterilizes: using high-temperature short-time sterilization, temperature controls at 110 DEG C, maintains 5s, be transferred to intermediate storage tank after sterilizing；
(9) it is spray-dried: oyster hydrolyzate in intermediate storage tank being squeezed into spray drying tower through pump and is spray-dried, into
At 170 DEG C, outlet temperature carries out receipts powder at 90 DEG C for mouth temperature control.
Product preparation method:
(1) feedstock processing: maca, rhizoma polygonati cleaning clean, dry, crush, cross 20 meshes；
(2) low temperature expanding: maca, rhizoma polygonati are respectively charged into Bulking tank, are blown into air-flow by compressor, temperature gradually rises in tank
Up to 100 DEG C, in tank formed certain pressure be 0.8Mpa, the time be 20s after release stress；
(3) it crushes: pueraria root powder, the rhizoma polygonati powder after extruding is crushed again, and cross 60 meshes；
(4) ostreae testa pulverata prepare: fresh oyster meat is cleaned, be crushed, crush mashing, enzymatic hydrolysis, enzyme deactivation, separation and purification, concentration,
The techniques such as sterilizing, spray drying are made；
(5) it mixes: weighing ostreae testa pulverata, D-sorbite, maltodextrin, magnesium stearate etc. in three-dimensional mixer according to formula ratio
In mixed, incorporation time 30min；
(6) tabletting: after mixing, tabletting is carried out with tablet press machine.
Embodiment 5
Product formula amount: 45 parts of pueraria root powder, 20 parts of D-sorbite, 15 parts of maltodextrin, 11 parts of rhizoma polygonati powder, 7 parts of ostreae testa pulverata,
2 parts of magnesium stearate.
The preparation method of ostreae testa pulverata:
(1) it is crushed: fresh oyster being put into crusher and is crushed；
(2) it cleans: broken oyster being put into service sink, is cleaned and is impregnated with 0.3mol/L NaOH solution
Then 13h is washed till neutrality with clear water:
(3) it crushes mashing: broken oyster being put into colloid mill and is further crushed, purified water is added, is configured to expect
Liquor ratio is 1: 2, makes oyster at slurry condition；
(4) it digests: being digested using composite hydrolytic enzyme, acid protease, papain, neutral proteinase, added
Amount is the 0.7 ‰ of oyster quality, and at 50 DEG C, enzymolysis time is controlled in 2h, solution ph 4.5 for hydrolysis temperature control；
(5) enzyme deactivation: after enzymatic hydrolysis, the temperature of enzymatic vessel is increased to 85 DEG C, maintains 35min；
(6) separation and purification: the feed liquid after enzyme deactivation is released from enzymatic vessel, is once filtered by plate filter,
It is filtered using film and carries out secondary filter, by nanofiltration membrane desalination, obtain purification oyster hydrolyzate；
(7) be concentrated: oyster hydrolyzate is by negative pressure inspissator, and control vacuum degree is in 0.6Mpa, when mass concentration is 42%,
Stop concentration；
(8) it sterilizes: using high-temperature short-time sterilization, temperature controls at 120 DEG C, maintains 5s, be transferred to intermediate storage tank after sterilizing；
(9) it is spray-dried: oyster hydrolyzate in intermediate storage tank being squeezed into spray drying tower through pump and is spray-dried, into
At 180 DEG C, outlet temperature carries out receipts powder at 92 DEG C for mouth temperature control.
Product preparation method:
(1) feedstock processing: maca, rhizoma polygonati cleaning clean, dry, crush, cross 20 meshes；
(2) low temperature expanding: maca, rhizoma polygonati are respectively charged into Bulking tank, are blown into air-flow by compressor, temperature gradually rises in tank
Up to 105 DEG C, in tank formed certain pressure be 1.0Mpa, the time be 30s after release stress；
(3) it crushes: pueraria root powder, the rhizoma polygonati powder after extruding is crushed again, and cross 60 meshes；
(4) ostreae testa pulverata prepare: fresh oyster meat is cleaned, be crushed, crush mashing, enzymatic hydrolysis, enzyme deactivation, separation and purification, concentration,
The techniques such as sterilizing, spray drying are made；
(5) mix: according to formula ratio weigh extruding pueraria root powder, extruding rhizoma polygonati powder, ostreae testa pulverata, D-sorbite, maltodextrin,
Magnesium stearate etc. is mixed in three-dimensional mixer, incorporation time 40min；
(6) tabletting: after mixing, tabletting is carried out with tablet press machine.
Embodiment 6
Product formula amount: 54.5 parts of pueraria root powder, 15 parts of D-sorbite, 13 parts of maltodextrin, 10 parts of rhizoma polygonati powder, ostreae testa pulverata 6
Part, 1.5 parts of magnesium stearate
The preparation method of ostreae testa pulverata:
(1) it is crushed: fresh oyster being put into crusher and is crushed；
(2) it cleans: broken oyster being put into service sink, is cleaned and is impregnated with 0.4mol/L NaOH solution
Then 14h is washed till neutrality with clear water；
(3) it crushes mashing: broken oyster being put into colloid mill and is further crushed, purified water is added, is configured to expect
Liquor ratio is 1: 2, makes oyster at slurry condition；
(4) it digests: being digested using composite hydrolytic enzyme, papain, neutral proteinase, bromelain, added
Amount is the 0.8 ‰ of oyster quality, and at 55 DEG C, enzymolysis time is controlled in 2.5h, solution ph 5.0 for hydrolysis temperature control；
(5) enzyme deactivation: after enzymatic hydrolysis, the temperature of enzymatic vessel is increased to 90 DEG C, maintains 40min；
(6) separation and purification: the feed liquid after enzyme deactivation is released from enzymatic vessel, is once filtered by plate filter,
It is filtered using film and carries out secondary filter, by nanofiltration membrane desalination, obtain purification oyster hydrolyzate；
(7) be concentrated: oyster hydrolyzate is by negative pressure inspissator, and control vacuum degree is in 0.7Mpa, when mass concentration is 45%,
Stop concentration；
(8) it sterilizes: using high-temperature short-time sterilization, temperature controls at 125 DEG C, maintains 8s, be transferred to intermediate storage tank after sterilizing；
(9) it is spray-dried: oyster hydrolyzate in intermediate storage tank being squeezed into spray drying tower through pump and is spray-dried, into
At 190 DEG C, outlet temperature carries out receipts powder at 95 DEG C for mouth temperature control.
Product preparation method:
(1) feedstock processing: maca, rhizoma polygonati cleaning clean, dry, crush, cross 20 meshes；
(2) low temperature expanding: maca, rhizoma polygonati are respectively charged into Bulking tank, are blown into air-flow by compressor, temperature gradually rises in tank
Up to 100 DEG C, in tank formed certain pressure be 0.5Mpa, the time be 25s after release stress；
(3) it crushes: pueraria root powder, the rhizoma polygonati powder after extruding is crushed again, and cross 60 meshes；
(4) ostreae testa pulverata prepare: fresh oyster meat is cleaned, be crushed, crush mashing, enzymatic hydrolysis, enzyme deactivation, separation and purification, concentration,
The techniques such as sterilizing, spray drying are made；
(5) mix: according to formula ratio weigh extruding pueraria root powder, extruding rhizoma polygonati powder, ostreae testa pulverata, D-sorbite, maltodextrin,
Magnesium stearate etc. is mixed in three-dimensional mixer, incorporation time 45min；
(6) tabletting: after mixing, tabletting is carried out with tablet press machine.
Embodiment 7
Product formula amount: 60 parts of pueraria root powder, 11 parts of D-sorbite, 11 parts of maltodextrin, 11 parts of rhizoma polygonati powder, 6 parts of ostreae testa pulverata,
1 part of magnesium stearate.
The preparation method of ostreae testa pulverata:
(1) it is crushed: fresh oyster being put into crusher and is crushed；
(2) it cleans: broken oyster being put into service sink, is cleaned and is impregnated with 0.5mol/L NaOH solution
Then 15h is washed till neutrality with clear water；
(3) it crushes mashing: broken oyster being put into colloid mill and is further crushed, purified water is added, is configured to expect
Liquor ratio is 1: 3, makes oyster at slurry condition；
(4) it digests: being digested using composite hydrolytic enzyme, acid protease, papain, bromelain, added
Amount is the 1.0 ‰ of oyster quality, and at 60 DEG C, enzymolysis time is controlled in 3h, solution ph 6.0 for hydrolysis temperature control；
(5) enzyme deactivation: after enzymatic hydrolysis, the temperature of enzymatic vessel is increased to 70 DEG C, maintains 50min；
(6) separation and purification: the feed liquid after enzyme deactivation is released from enzymatic vessel, is once filtered by plate filter,
It is filtered using film and carries out secondary filter, by nanofiltration membrane desalination, obtain purification oyster hydrolyzate；
(7) be concentrated: oyster hydrolyzate is by negative pressure inspissator, and control vacuum degree is in 0.6Mpa, when mass concentration is 50%,
Stop concentration；
(8) it sterilizes: using high-temperature short-time sterilization, temperature controls at 130 DEG C, maintains 8s, be transferred to intermediate storage tank after sterilizing；
(9) it is spray-dried: oyster hydrolyzate in intermediate storage tank being squeezed into spray drying tower through pump and is spray-dried, into
At 195 DEG C, outlet temperature carries out receipts powder at 98 DEG C for mouth temperature control.
Product preparation method:
(1) feedstock processing: maca, rhizoma polygonati cleaning clean, dry, crush, cross 20 meshes；
(2) low temperature expanding: maca, rhizoma polygonati are respectively charged into Bulking tank, are blown into air-flow by compressor, temperature gradually rises in tank
Up to 110 DEG C, in tank formed certain pressure be 0.8Mpa, the time be 40s after release stress；
(3) it crushes: pueraria root powder, the rhizoma polygonati powder after extruding is crushed again, and cross 60 meshes；
(4) ostreae testa pulverata prepare: fresh oyster meat is cleaned, be crushed, crush mashing, enzymatic hydrolysis, enzyme deactivation, separation and purification, concentration,
The techniques such as sterilizing, spray drying are made；
(5) mix: according to formula ratio weigh extruding pueraria root powder, extruding rhizoma polygonati powder, ostreae testa pulverata, D-sorbite, maltodextrin,
Magnesium stearate etc. is mixed in three-dimensional mixer, incorporation time 50min；
(6) tabletting: after mixing, tabletting is carried out with tablet press machine.
Claims (6)
1. a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, which is characterized in that according to parts by weight
It specifically includes that
20~60 parts of pueraria root powder, 10~40 parts of D-sorbite
5~40 parts of maltodextrin, 5~30 parts of rhizoma polygonati powder
5~20 parts of ostreae testa pulverata, 0.1~3 part of magnesium stearate.
2. a kind of according to claim 1, composition and preparation method thereof for alleviating physical fatigue strengthen immunity, feature exists
In specifically including that according to parts by weight
30~50 parts of pueraria root powder, 15~30 parts of D-sorbite
10~30 parts of maltodextrin, 10~20 parts of rhizoma polygonati powder
8~15 parts of ostreae testa pulverata, 1~2.5 part of magnesium stearate.
3. a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity, feature exists according to claim 2
In specifically including that according to parts by weight
40 parts of pueraria root powder, 20 parts of D-sorbite
15 parts of maltodextrin, 13 parts of rhizoma polygonati powder
10 parts of ostreae testa pulverata, 2 parts of magnesium stearate.
4. according to claim 1,2 or 3, a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity is special
Sign is that oyster powder preparation technique is as follows:
(1) it is crushed: fresh oyster being put into crusher and is crushed；
(2) it cleans: broken oyster being put into service sink, is cleaned simultaneously with 0.1mol/L~0.5mol/L NaOH solution
12~18h is impregnated, is then washed till neutrality with clear water；
(3) it crushes mashing: broken oyster being put into colloid mill and is further crushed, purified water is added, is configured to solid-liquid ratio
It is 1: 1~1: 3, makes oyster at slurry condition；
(4) it digests: being digested using composite hydrolytic enzyme, composite hydrolytic enzyme is acid protease, papain, neutral protein
Enzyme, one or more of bromelain, additive amount are 0.5 ‰~the 1.0 ‰ of oyster quality, and hydrolysis temperature is controlled at 45 DEG C
~60 DEG C, enzymolysis time is controlled in 1h~4h, solution ph 4.0~7.0；
(5) enzyme deactivation: after enzymatic hydrolysis, the temperature of enzymatic vessel is increased to 70 DEG C~90 DEG C, maintains 30min~60min；
(6) separation and purification: the feed liquid after enzyme deactivation is released from enzymatic vessel, is once filtered by plate filter, then pass through
It crosses film filtering and carries out secondary filter, by nanofiltration membrane desalination, obtain purification oyster hydrolyzate；
(7) be concentrated: oyster hydrolyzate controls vacuum degree in 0.5Mpa~1.0Mpa, when mass concentration exists by negative pressure inspissator
40%~50%, stop concentration；
(8) it sterilizes: using high-temperature short-time sterilization, temperature controls at 110 DEG C~130 DEG C, maintains 5s~10s, be transferred to after sterilizing
Between storage tank；
(9) it is spray-dried: oyster hydrolyzate in intermediate storage tank being squeezed into spray drying tower through pump and is spray-dried, import temperature
At 160 DEG C~200 DEG C, outlet temperature carries out receipts powder at 90 DEG C~100 DEG C for degree control.
5. according to claim 1,2 or 3, a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity is special
Sign is that pueraria root powder, rhizoma polygonati powder uses cryogenic high pressure bulking process, the specific process is as follows:
(1) maca, rhizoma polygonati are respectively washed completely, clean, dry, crush, and cross 20 meshes；
(2) maca, rhizoma polygonati are respectively charged into Bulking tank, are blown into air-flow by compressor, temperature, which is stepped up, in tank reaches 85~105
DEG C, in tank formed certain pressure be 0.8~1.5Mpa, the time be 20~40s after release stress.
6. according to claim requirement 1,2 or 3, a kind of composition and preparation method thereof for alleviating physical fatigue strengthen immunity,
It is characterized in that, specific preparation process is as follows:
(1) feedstock processing: maca, rhizoma polygonati cleaning clean, dry, crush, cross 20 meshes；
(2) low temperature expanding: maca, rhizoma polygonati are respectively charged into Bulking tank, are blown into air-flow by compressor, temperature, which is stepped up, in tank reaches
To 85~105 DEG C, in tank formed certain pressure be 0.8~1.5Mpa, the time be 20~40s after release stress；
(3) it crushes: pueraria root powder, the rhizoma polygonati powder after extruding is crushed again, and cross 60 meshes；
(4) prepared by ostreae testa pulverata: fresh oyster meat is cleaned, is crushed, crushes mashing, enzymatic hydrolysis, enzyme deactivation, separation and purification, be concentrated, go out
The techniques such as bacterium, spray drying are made；
(5) mix: according to formula ratio weigh ostreae testa pulverata, D-sorbite, maltodextrin, magnesium stearate etc. in three-dimensional mixer into
Row mixing, incorporation time 30min~60min；
(6) tabletting: after mixing, tabletting is carried out with tablet press machine.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2011019210A2 (en) * | 2009-08-11 | 2011-02-17 | Kim Younjin | Dietary supplement, feed and pharmaceutical composition containing chia seed and maca, and preparation method thereof |
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