CN109832298A - A kind of medical sterilization formulation - Google Patents

A kind of medical sterilization formulation Download PDF

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Publication number
CN109832298A
CN109832298A CN201711221688.6A CN201711221688A CN109832298A CN 109832298 A CN109832298 A CN 109832298A CN 201711221688 A CN201711221688 A CN 201711221688A CN 109832298 A CN109832298 A CN 109832298A
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CN
China
Prior art keywords
fungicide
parts
activin
biguanides
medical sterilization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711221688.6A
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Chinese (zh)
Inventor
张�焕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JIANGSU SHUANGSHENG MEDICAL EQUIPMENT CO Ltd
Original Assignee
JIANGSU SHUANGSHENG MEDICAL EQUIPMENT CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JIANGSU SHUANGSHENG MEDICAL EQUIPMENT CO Ltd filed Critical JIANGSU SHUANGSHENG MEDICAL EQUIPMENT CO Ltd
Priority to CN201711221688.6A priority Critical patent/CN109832298A/en
Publication of CN109832298A publication Critical patent/CN109832298A/en
Pending legal-status Critical Current

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  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention discloses a kind of medical sterilization formulations comprising alkyl biguanides fungicide, povidone iodine, activin, carbamate and deionized water.The beneficial effects of the present invention are: component proportion is scientific and reasonable, alkyl biguanides fungicide is combined with activin and carbamate, and stability is high, have sterilizing power strong simultaneously, bactericidal range is wide, and irritation is minimum, easy cleaning, without allergic reaction, it is quick and easy and safe.

Description

A kind of medical sterilization formulation
Technical field
The present invention relates to a kind of fungicide more particularly to a kind of medical sterilization formulations.
Background technique
Disinfectant can be divided into bactericidal agent, high effect disinfectants, middle effect disinfectants and low effect disinfectants according to the level of its effect. Bactericidal agent can kill all microorganisms and reach sterilizing requirement, including formaldehyde, glutaraldehyde, ethylene oxide, Peracetic acid, peroxide Change hydrogen, chlorine dioxide and hypochlorous acid etc..High effect disinfectants are to all bacterial propagule (including mycobacteria), virus, fungies etc. Killing rate up to 99.9999% or more, also have certain killing effect to bacterial spore.Middle effect disinfectants are only to bacterial reproduction The rates of killing such as body, virus, fungi go out 99.9999%, to bacterial spore then without killing effect.This kind of fungicide includes disappearing containing iodine Toxic agent, disinfectant phenolic etc..Low effect disinfectants, which can only kill bacterial propagule, virus, fungi etc., can 99.9% killing rate.This Class disinfectant has the quaternary ammonium salts such as benzalkonium bromide, benzethonium chloride;The biguanides such as Chlorhexidine, A Xi halt, poly- hexyl biguanides;Mercury, The metal ions class such as silver, copper;And Chinese herbal disinfectant.
Bactericidal agent, high effect disinfectants and middle effect disinfectants generally by strong oxidizing property fungicide, strong reducing property fungicide or It is made of phenol compounds fungicide, bactericidal effect is very strong, but also has extremely strong corrosivity, irritation, toxicity and to people The nocuity of body.If skin can be burnt into black immediately by o-phthalaldehyde and skin contact, peracetic acid etc. can immediately burn skin It has a severe pain at white unbearably, the respiratory tract of the fungicide of class containing chlorine meeting intense stimulus people.Disinfectant phenolic can be through the skin of baby It is absorbed with damaged wound and generates virulent property, damage the nervous system of baby, therefore be not suitable as medical article sterilizing, it is more uncomfortable Close skin antiseptic.The metal ions class disinfectant such as mercury, silver, copper is not degradable, can pollute the environment.
On the other hand, even to efficient and middle effect disinfectants, germ is also just generating increasingly stronger drug resistance.Such as penta 2 Aldehyde has drug resistance to mycobacterium, such as Mycobacterium chelonei, people tulase, and it is contour that o-phthalaldehyde does not kill bacterial spore again Drug resistance venereal bacteria.Disinfectant phenolic becomes the potential cause of skin infection to the comprehensive drug resistance of Gram-negative bacteria.Metal ion disappears Toxic agent is to Pseudomonas aeruginosa, enterococcus, golden staphylococcus, pseudomonad drug resistance.Therefore market, which needs, more effectively, more easily disappears Toxic agent comes out.
The advantages of low effect disinfectants quaternary ammonium salt and biguanides fungicide be the corrosivity to object, the pollution to environment, Human body irritation and toxicity are smaller, but its bactericidal effect is also very low, and no matter being single use or mix to use cannot kill Dead many strains, it is difficult to deal with the extensive popular virus occurred again and again since 21st century, such as SARS, bird flu, swine flu Deng.
Therefore, to solve the above problems, providing a kind of new technical solution.
Summary of the invention
The present invention provides a kind of medical sterilization formulation.
The technical solution adopted by the present invention is that:
A kind of medical sterilization formulation comprising alkyl biguanides fungicide, povidone iodine, activin, carbamate and go Ionized water.
Further, said components are respectively as follows: by weight
20-30 parts of alkyl biguanides fungicide;
5-10 parts of povidone iodine;
8-15 parts of activin;
4-7 parts of carbamate;
30-40 parts of deionized water.
Further, the alkyl biguanides fungicide is poly- hexyl methyl biguanides or alexidine.
Further, the pH value of the fungicide is 11~13.
The beneficial effects of the present invention are: component proportion is scientific and reasonable, alkyl biguanides fungicide and activin and amino first Acid esters combines, and stability is high, while having sterilizing power strong, and bactericidal range is wide, and irritation is minimum, easy cleaning, without allergic reaction, It is quick and easy and safe.
Specific embodiment
In order to deepen the understanding of the present invention, the present invention will be described in further detail with reference to the examples below, the embodiment For explaining only the invention, it does not restrict the protection scope of the present invention.
Embodiment 1
A kind of medical sterilization formulation comprising alkyl biguanides fungicide, povidone iodine, activin, carbamate and go Ionized water, said components are respectively as follows: by weight
20 parts of poly- hexyl methyl biguanides;
5 parts of povidone iodine;
8 parts of activin;
4 parts of carbamate;
30 parts of deionized water.
The pH value of fungicide is 11.
The beneficial effects of the present invention are: component proportion is scientific and reasonable, alkyl biguanides fungicide and activin and amino first Acid esters combines, and stability is high, while having sterilizing power strong, and bactericidal range is wide, and irritation is minimum, easy cleaning, without allergic reaction, It is quick and easy and safe.
Embodiment 2
A kind of medical sterilization formulation comprising alkyl biguanides fungicide, povidone iodine, activin, carbamate and go Ionized water, said components are respectively as follows: by weight
25 parts of alexidine;
7 parts of povidone iodine;
12 parts of activin;
5 parts of carbamate;
35 parts of deionized water.
The pH value of fungicide is 11~12.
The beneficial effects of the present invention are: component proportion is scientific and reasonable, alkyl biguanides fungicide and activin and amino first Acid esters combines, and stability is high, while having sterilizing power strong, and bactericidal range is wide, and irritation is minimum, easy cleaning, without allergic reaction, It is quick and easy and safe.
Embodiment 3
A kind of medical sterilization formulation comprising alkyl biguanides fungicide, povidone iodine, activin, carbamate and go Ionized water, said components are respectively as follows: by weight
30 parts of poly- hexyl methyl biguanides;
10 parts of povidone iodine;
15 parts of activin;
7 parts of carbamate;
40 parts of deionized water.
The pH value of fungicide is 13.
The beneficial effects of the present invention are: component proportion is scientific and reasonable, alkyl biguanides fungicide and activin and amino first Acid esters combines, and stability is high, while having sterilizing power strong, and bactericidal range is wide, and irritation is minimum, easy cleaning, without allergic reaction, It is quick and easy and safe.
The above described is only a preferred embodiment of the present invention, being not the limit for making any other form to the present invention System, and made any modification or equivalent variations according to the technical essence of the invention, still fall within present invention model claimed It encloses.

Claims (4)

1. a kind of medical sterilization formulation, it is characterised in that: it includes alkyl biguanides fungicide, povidone iodine, activin, ammonia Carbamate and deionized water.
2. a kind of medical sterilization formulation according to claim 1, it is characterised in that: said components are distinguished by weight Are as follows:
20-30 parts of alkyl biguanides fungicide;
5-10 parts of povidone iodine;
8-15 parts of activin;
4-7 parts of carbamate;
30-40 parts of deionized water.
3. a kind of medical sterilization formulation according to claim 1 or 2, it is characterised in that: the alkyl biguanides sterilization Agent is poly- hexyl methyl biguanides or alexidine.
4. a kind of medical sterilization formulation according to claim 1, it is characterised in that: the pH value of the fungicide be 11~ 13。
CN201711221688.6A 2017-11-29 2017-11-29 A kind of medical sterilization formulation Pending CN109832298A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711221688.6A CN109832298A (en) 2017-11-29 2017-11-29 A kind of medical sterilization formulation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711221688.6A CN109832298A (en) 2017-11-29 2017-11-29 A kind of medical sterilization formulation

Publications (1)

Publication Number Publication Date
CN109832298A true CN109832298A (en) 2019-06-04

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CN201711221688.6A Pending CN109832298A (en) 2017-11-29 2017-11-29 A kind of medical sterilization formulation

Country Status (1)

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CN (1) CN109832298A (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102669141A (en) * 2005-07-08 2012-09-19 Isp投资有限公司 Microbicidal composition
CN103735568A (en) * 2013-12-19 2014-04-23 江西草珊瑚消毒用品有限公司 Compound guanidine complex iodine skin mucosa disinfectant and preparation method thereof
CN104644667A (en) * 2015-02-12 2015-05-27 天津大学 Compound disinfectant and preparation method thereof
CN105126107A (en) * 2015-09-21 2015-12-09 山东威高药业股份有限公司 Liquid wound dressing
WO2016094084A1 (en) * 2014-12-09 2016-06-16 The Trustees Of Columbia University In The City Of New York Bio-film resistant surfaces

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102669141A (en) * 2005-07-08 2012-09-19 Isp投资有限公司 Microbicidal composition
CN103735568A (en) * 2013-12-19 2014-04-23 江西草珊瑚消毒用品有限公司 Compound guanidine complex iodine skin mucosa disinfectant and preparation method thereof
WO2016094084A1 (en) * 2014-12-09 2016-06-16 The Trustees Of Columbia University In The City Of New York Bio-film resistant surfaces
CN104644667A (en) * 2015-02-12 2015-05-27 天津大学 Compound disinfectant and preparation method thereof
CN105126107A (en) * 2015-09-21 2015-12-09 山东威高药业股份有限公司 Liquid wound dressing

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
叶伟胜 等: "《骨质疏松内固定》", 30 September 2007, 天津科学技术出版社 *
张流波 等: "《医学消毒学最新进展》", 31 December 2015, 人民军医出版社 *

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Application publication date: 20190604

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