CN109820772B - Antibacterial skin-care wet tissue and preparation method thereof - Google Patents

Antibacterial skin-care wet tissue and preparation method thereof Download PDF

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CN109820772B
CN109820772B CN201811503581.5A CN201811503581A CN109820772B CN 109820772 B CN109820772 B CN 109820772B CN 201811503581 A CN201811503581 A CN 201811503581A CN 109820772 B CN109820772 B CN 109820772B
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wet tissue
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camphor
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extract
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CN109820772A (en
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郑钦方
汪冶
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Beijing Tiancheng Huipu Information Technology Co ltd
Zhejiang Shini Nursing Products Technology Co.,Ltd.
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Huaihua Wulingsan Dong Pharmaceutical Technology Development Co ltd
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Abstract

The invention relates to an antibacterial skin-care wet tissue and a preparation method thereof, wherein the antibacterial skin-care wet tissue comprises a wet tissue base material and a wet tissue immersion liquid, and the wet tissue immersion liquid comprises the following components in parts by mass: 0.2-1 part of camphor leaf essential oil of Hongya camphor, 0.2-1 part of borneol extract and 60-70 parts of camphor leaf hydrolat of Hongya camphor. The antibacterial skin care wet tissue contains the components of the natural plant extract, and is reasonable in proportioning relation, mild and free of skin irritation. The antibacterial skin-care wet tissue not only has the conventional antibacterial skin-care function, but also has the effects of relieving red and swollen skin, itchy skin and pain after being bitten by mosquitoes.

Description

Antibacterial skin-care wet tissue and preparation method thereof
Technical Field
The invention relates to the technical field of wet tissues, in particular to an antibacterial skin-care wet tissue and a preparation method thereof.
Background
The wet tissue is a disposable cleaning sanitary product prepared by selecting a high-permeability base material, folding, humidifying and packaging, has the characteristics of basic functions of cleaning and moisturizing skin, convenience in carrying and the like, and becomes an essential cleaning product in daily life of people. The wet tissue generally consists of a base material and liquid medicine. Although some wet tissues with antibacterial effect exist in the market, the raw materials are complex, the preparation and extraction processes are complicated, the cost is high, the application range is limited, and more importantly, chemical bactericides such as methylisothiazolinone and methylchloroisothiazolinone are usually used in the wet tissues, and the chemical bactericides have moderate toxicity, irritation and potential safety hazard in use. In addition, in order to improve the antibacterial property of the wet tissue, high-concentration ethanol is usually added into the wet tissue, the concentration of the ethanol can exceed 60 percent, the phenomenon of excessive dissolution of sebum on the surface layer of the skin can occur, the skin is dried, even allergic reaction can be caused, and particularly for sensitive skin, the allergic reaction such as rash, erythema and the like is often caused.
Disclosure of Invention
Based on the antibacterial skin-care wet tissue containing the natural extraction components and the preparation method thereof are provided.
An antibacterial skin care wet wipe, comprising: the wet tissue base material and the wet tissue immersion liquid comprise the following components in parts by mass:
0.2-1 part of camphor leaf essential oil of cinnamomum hongeucalypti camphor
0.2-1 part of borneol extract and
60-70 parts of camphor leaf hydrolat of cinnamomum hongeucalypti camphor.
The antibacterial skin care wet tissue contains the components of the natural plant extract, and is reasonable in proportioning relation, mild and free of skin irritation. The antibacterial skin-care wet tissue not only has the conventional skin-care function, but also has the effects of resisting bacteria and relieving red and swollen skin and itchy and painful skin after being bitten by mosquitoes. Specifically, the D-borneol in the borneol extract has the effects of resisting bacteria, inducing resuscitation, refreshing mind, cooling and relieving pain. The cineole oil in the camphor leaf essential oil of the cinnamomum japonicum champ has the functions of avoiding dirty, relieving itching, reducing swelling and relieving pain, and particularly has the obvious effects of reducing swelling and relieving itching on the affected part bitten by mosquitoes. And the camphor leaf essential oil has good inhibition effect on gram-negative bacteria represented by escherichia coli. The camphor leaf pure dew of the cinnamomum japonicum camphora is rich in mineral ions, and under the microenvironment rich in mineral ions provided by the camphor leaf pure dew of the cinnamomum japonicum camphora, eucalyptol and d-borneol are transported to the cuticle of the skin in a transmembrane transportation mode, and then the eucalyptol and d-borneol go deep into the affected part to perform antibiosis and antiphlogosis. In addition, eucalyptol is a natural preservative, which can prevent the wet tissue base material from breeding bacteria due to long-term soaking.
In one embodiment, the weight of the d-borneol in the borneol extract accounts for more than 70% of the weight of the borneol extract.
In one embodiment, the mass of the cineole in the camphor leaf essential oil accounts for 45% -50% of the mass of the camphor leaf essential oil.
In one embodiment, the wet tissue immersion liquid further comprises bletilla striata extract and poria cocos extract.
In one embodiment, the rhizoma bletillae extract and the poria cocos extract are 1-3 parts and 0.2-1 part by mass respectively.
In one embodiment, the mass ratio of the wet tissue base material to the wet tissue immersion liquid is greater than 1.8: 1.
In one embodiment, the wet tissue immersion fluid further comprises one or two of a humectant and a surfactant.
In one embodiment, the wet tissue immersion liquid comprises a humectant and a surfactant, wherein the humectant is 2-10 parts by mass, and the surfactant is 1-6 parts by mass.
The invention also provides a preparation method of the antibacterial skin-care wet tissue.
A preparation method of an antibacterial skin-care wet tissue comprises the following steps: uniformly mixing 0.2-1 part by mass of camphor leaf essential oil of Hongya camphor, 0.2-1 part by mass of borneol extract and 60-70 parts by mass of camphor leaf hydrolat of Hongya camphor to obtain wet tissue immersion liquid, and immersing a wet tissue base material into the wet tissue immersion liquid.
The preparation method of the antibacterial skin-care wet tissue is simple, and the chemically synthesized antibacterial agent is not added, so that the prepared wet tissue has the conventional antibacterial function, and also has the effects of relieving red and swollen skin and itchy and painful skin after being bitten by mosquitoes.
In one embodiment, the preparation of the wet tissue immersion liquid comprises the following steps: the wet tissue immersion liquid is prepared by uniformly mixing 0.2-1 part by mass of camphor leaf essential oil of Hongya camphor, 0.2-1 part by mass of borneol extract, 60-70 parts by mass of camphor leaf hydrolat of Hongya camphor and 1-6 parts by mass of surfactant to obtain a mixture, adding 1-3 parts by mass of white and extract, 0.2-1 part by mass of poria extract and 2-10 parts by mass of humectant into the mixture under stirring, and uniformly stirring.
Detailed Description
The present invention will be described in detail with reference to the following embodiments in order to make the aforementioned objects, features and advantages of the invention more comprehensible. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention can be embodied in many different forms than those herein described and one skilled in the art can make similar modifications without departing from the spirit of the invention and it is therefore not limited to the specific embodiments disclosed below.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
An embodiment of the present invention provides an antibacterial skin-care wet tissue, which includes: the wet tissue comprises a wet tissue base material and a wet tissue immersion liquid, wherein the wet tissue immersion liquid comprises the following components in parts by mass:
0.2-1 part of camphor leaf essential oil of cinnamomum hongeucalypti camphor
0.2-1 part of borneol extract and
60-70 parts of camphor leaf hydrolat of cinnamomum hongeucalypti camphor.
The material of the wet towel base material can be selected from, but not limited to, nonwoven fabric, fiber paper or high-permeability polyethylene film. The fiber paper can be bamboo fiber paper or wood fiber paper, and can also be a composite wet tissue base material prepared by mixing bamboo fiber paper and wood fiber paper according to a certain proportion for pulping, preferably, the mass ratio of the bamboo fiber paper to the wood fiber paper is 1:1-1:2, and it can be understood that the mass ratio of the bamboo fiber paper to the wood fiber paper can be 1:1, the mass ratio of the bamboo fiber paper to the wood fiber paper can also be 1:2, and most preferably, the mass ratio of the bamboo fiber paper to the wood fiber paper is 1: 1.5. When the hypertonic polyethylene film is selected for use as the wet tissue base material, the holes penetrating through the polyethylene film can be better formed in the wet tissue immersion liquid, compared with the traditional non-woven fabric, the wet tissue immersion liquid can absorb more liquid medicine, when the affected parts with red swelling and itching pain after being bitten by mosquitoes need to be treated or relieved, the affected parts can be flapped gently, and the back surface of the wet tissue can be extruded out of the affected parts quickly to treat the mosquito bite. Preferably, a high-permeability polyethylene film with the porosity of 70% -80% is selected as the wet tissue base material.
In one embodiment, the mass ratio of the wet tissue base material to the wet tissue immersion liquid is greater than 1.7: 1.
In one embodiment, the mass ratio of the wet tissue base material to the wet tissue immersion liquid is 2:1-3: 1. Preferably, the mass ratio of the high-permeability polyethylene film to the wet tissue immersion liquid is 2.5: 1.
The cinnamomum japonicum camphora is a tree species of evergreen trees in cinnamomum of Lauraceae, the cinnamomum japonicum camphora leaves are rich in camphora leaf essential oil, the essential oil extracted by cultivation is widely applied to industries such as medicine, essence, spice, cosmetics and the like, and the cinnamomum japonicum camphora has wide market prospect. The main active component of the camphor leaf essential oil of the cinnamomum hongeudesmum is cineole which has the functions of avoiding dirty, relieving itching, reducing swelling and relieving pain, and especially has obvious effects of reducing swelling and relieving itching on the affected part bitten by mosquitoes. The inventor finds that eucalyptol has good inhibiting effect on gram-negative bacteria represented by escherichia coli. In addition, the camphor leaf essential oil of the cinnamomum hongeuense also contains natural spice components such as camphene, pinene and the like, so that natural herbal fragrance can be brought to the wet tissue, and the pleasure feeling can be brought while the refreshing effect is achieved.
In one embodiment, the mass of the cineole in the camphor leaf essential oil of the cinnamomum japonicum camphora accounts for 45% -50% of the mass of the camphor leaf essential oil of the cinnamomum japonicum camphora. The bacteriostatic effect of the antibacterial skin-care wet tissue can be further enhanced. Preferably, the mass of the cineole in the camphor leaf essential oil of the cinnamomum japonicum camphora accounts for 48% of the mass of the camphor leaf essential oil of the cinnamomum japonicum camphora.
Wherein the effective component of Borneolum Syntheticum extract is mainly d-borneol which has antibacterial, resuscitation inducing, refreshing, analgesic, and mosquito repelling effects.
In one embodiment, the mass of the d-borneol in the borneol extract accounts for more than 70% of the mass of the borneol extract. The bacteriostatic effect of the antibacterial skin-care wet tissue can be further enhanced. Preferably, the mass of the d-borneol in the borneol extract accounts for more than 75% of the mass of the borneol extract, and further, the mass of the d-borneol in the borneol extract accounts for 75% -95% of the mass of the borneol extract.
The camphor leaf pure dew of the Hongya camphor disclosed by the invention is rich in mineral ions, and under the microenvironment rich in mineral ions provided by the camphor leaf pure dew of the Hongya camphor, eucalyptol and d-borneol are favorably transported into the cuticle of skin in a transmembrane transport mode, and then the eucalyptol and the d-borneol penetrate into the affected part to perform antibiosis and antiphlogosis. That is, the camphor leaf hydrolat of the cinnamomum hongkongense camphor provides a microenvironment pathway for the effective substances to enter the affected part of the skin.
In one embodiment, the wet tissue immersion liquid further comprises bletilla striata extract and poria cocos extract.
The bletilla striata extract mainly has the effects of detumescence, granulation promotion and convergence, and particularly has good inhibition effect on gram-negative bacteria such as bacillus subtilis, staphylococcus aureus and candida albicans. In addition, the bletilla striata extract contains natural bletilla striata gum components, and is compounded with a large amount of components for nourishing the skin, such as vitamins, amino acids and the like, so that the elasticity and the firmness of the skin can be enhanced after long-term use. Is a natural skin care agent.
The poria cocos extract mainly has the effects of improving skin injury, particularly has a good repairing effect on skin tissues scratched and damaged by qi oxygen, does not leave scars, and regulates the balance of the internal environment of the skin.
In one embodiment, the rhizoma bletillae extract and the poria cocos extract are 1-3 parts and 0.2-1 part by mass respectively.
In one embodiment, the wet tissue immersion liquid comprises the following components in parts by mass:
Figure BDA0001898846920000061
in one embodiment, the wet tissue immersion liquid further comprises one or both of a humectant and a surfactant, and preferably, the wet tissue immersion liquid comprises a combination of both a humectant and a surfactant. The humectant is 2-10 parts by mass and the surfactant is 1-6 parts by mass.
In one embodiment, the surfactant is mainly used for removing dirt and grease and cleaning, and the surfactant is also used for increasing the solubility of the camphor leaf essential oil of the cinnamomum japonicum, for example, before the surfactant is not used, a certain amount of camphor leaf essential oil is dissolved in camphor leaf pure dew of the cinnamomum japonicum, the solubility of the camphor leaf essential oil in the camphor leaf pure dew of the cinnamomum japonicum is 0.3mg/mL, and after the surfactant is added, the solubility of the camphor leaf essential oil in the camphor leaf pure dew of the cinnamomum japonicum is increased to 0.5 mg/mL. Moreover, the surfactant can also adjust the compatibility of oil phase components and water phase components in the wet tissue immersion liquid, reduce the surface tension of the interface, improve the stability of the wet tissue immersion liquid, and prevent the precipitation of active ingredients, namely camphor leaf essential oil and borneol extract.
In one embodiment, the surfactant is selected from one or more of polyoxyethylene hydrogenated castor oil, polyoxyethylene lauryl ether, and polysorbate, for example: the surfactant is selected from polyoxyethylene hydrogenated castor oil, polyoxyethylene hydrogenated castor oil and polyoxyethylene lauryl ether.
In one embodiment, the humectant is selected from one or both of glycerin or propylene glycol.
It is understood that the wet wipe impregnation fluid of the present invention may further include a preservative selected from one of benzoic acid or phenoxyethanol to increase the shelf life of the wet wipe.
In one embodiment, the wet tissue immersion liquid comprises the following components in parts by mass:
Figure BDA0001898846920000071
the antibacterial skin care wet tissue contains the components of the natural plant extract, and is reasonable in proportioning relation, mild and free of skin irritation. The antibacterial skin-care wet tissue not only has the conventional skin-care function, but also has the effects of resisting bacteria and relieving red and swollen skin and itchy and painful skin after being bitten by mosquitoes. Specifically, the D-borneol in the borneol extract has the effects of resisting bacteria, inducing resuscitation, refreshing mind, cooling and relieving pain. The cineole oil in the camphor leaf essential oil of the cinnamomum japonicum champ has the functions of avoiding dirty, relieving itching, reducing swelling and relieving pain, and particularly has the obvious effects of reducing swelling and relieving itching on the affected part bitten by mosquitoes. And the camphor leaf essential oil has good inhibition effect on gram-negative bacteria represented by escherichia coli. The camphor leaf pure dew of the cinnamomum japonicum camphora is rich in mineral ions, and under the microenvironment rich in mineral ions provided by the camphor leaf pure dew of the cinnamomum japonicum camphora, eucalyptol and d-borneol are transported to the cuticle of the skin in a transmembrane transportation mode, and then the eucalyptol and d-borneol go deep into the affected part to perform antibiosis and antiphlogosis. In addition, eucalyptol is a natural preservative, which can prevent the wet tissue base material from breeding bacteria due to long-term soaking.
The invention also provides a preparation method of the antibacterial skin-care wet tissue,
a preparation method of an antibacterial skin-care wet tissue comprises the following steps: uniformly mixing 0.2-1 part by mass of camphor leaf essential oil of Hongya camphor, 0.2-1 part by mass of borneol extract and 60-70 parts by mass of camphor leaf hydrolat of Hongya camphor to obtain wet tissue immersion liquid, and immersing a wet tissue base material into the wet tissue immersion liquid.
In one embodiment, the wet tissue substrate is immersed in the wet tissue immersion liquid for 30min-60min, so that the wet tissue substrate can fully absorb the swelling of the wet tissue immersion liquid.
In one embodiment, the preparation of the wet tissue immersion liquid comprises the following steps: firstly, 0.2-1 part by mass of camphor leaf essential oil of Hongya camphor, 0.2-1 part by mass of borneol extract, 60-70 parts by mass of camphor leaf hydrolat of Hongya camphor and 1-6 parts by mass of surfactant are uniformly mixed to obtain a mixture, and 1-3 parts by mass of white and extract, 0.2-1 part by mass of poria extract and 2-10 parts by mass of humectant are added into the mixture under the stirring state and are uniformly stirred to obtain the wet tissue immersion liquid.
In one embodiment, the preparation method of the antibacterial skin-care wet tissue comprises the following steps: 0.2-1 part by mass of camphor leaf essential oil of the cinnamomum hongkongense, 0.2-1 part by mass of borneol extract, 60-70 parts by mass of camphor leaf hydrolat of the cinnamomum hongkongense and 1-6 parts by mass of surfactant are uniformly mixed so as to fully dissolve the camphor leaf essential oil and the borneol extract of the cinnamomum hongkongense in the camphor leaf hydrolat of the cinnamomum hongkongense to obtain a mixture, wherein the surfactant is favorable for dissolving the camphor leaf essential oil and the borneol extract of the cinnamomum hongkongense in the camphor leaf hydrolat of the cinnamomum hongkongense. Then adding 1-3 parts by mass of the white fungus extract, 0.2-1 part by mass of the poria cocos extract and 2-10 parts by mass of the humectant into the mixture under stirring, uniformly stirring to obtain a wet tissue immersion liquid, and immersing a wet tissue base material into the wet tissue immersion liquid, wherein the mass ratio of the wet tissue base material to the wet tissue immersion liquid is more than 1.8: 1.
In one embodiment, the preparation method of the antibacterial skin-care wet tissue comprises the following steps: 0.4 part by mass of camphor leaf essential oil of the cinnamomum hongeucalypti camphor, 0.4 part by mass of borneol extract, 45 parts by mass of camphor leaf hydrolat of the cinnamomum hongcinerea camphor and 3 parts by mass of surfactant are uniformly mixed, so that the camphor leaf essential oil and the borneol extract of the cinnamomum hongcinerea camphor are fully dissolved in the camphor leaf hydrolat of the cinnamomum hongcinerea camphor to obtain a mixture, wherein the surfactant is favorable for dissolving the camphor leaf essential oil and the borneol extract of the cinnamomum hongcinerea camphor in the camphor leaf hydrolat of the cinnamomum hongcinerea camphor. Then adding 2 parts by mass of rhizoma bletillae extract, 0.5 part by mass of poria cocos extract and 4 parts by mass of humectant into the mixture under stirring, uniformly stirring to obtain a wet tissue immersion liquid, and immersing a wet tissue base material into the wet tissue immersion liquid, wherein the mass ratio of the wet tissue base material to the wet tissue immersion liquid is 2.5: 1.
The preparation method of the antibacterial skin-care wet tissue is simple, and the chemically synthesized antibacterial agent is not added, so that the prepared wet tissue has the conventional antibacterial function, and also has the effects of relieving red and swollen skin and itchy and painful skin after being bitten by mosquitoes.
In order that the objects and advantages of the invention will be more clearly understood, the invention is further described in detail below with reference to examples. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1
A preparation method of wet tissue comprises the following steps:
0.4 part by mass of camphor leaf essential oil (eucalyptol accounts for 43%) of Hongya camphor, 0.5 part by mass of borneol extract (D-borneol accounts for 70%) and 60 parts by mass of camphor leaf pure dew of Hongya camphor are uniformly mixed to obtain wet tissue immersion liquid, so that the camphor leaf essential oil and the borneol extract of Hongya camphor are fully dissolved in the camphor leaf pure dew of Hongya camphor, and then the non-woven fabric is immersed in the wet tissue immersion liquid, wherein the mass ratio of the non-woven fabric to the wet tissue immersion liquid is 2: 1.
Example 2
A preparation method of wet tissue comprises the following steps:
0.4 part by mass of camphor leaf essential oil (eucalyptol accounts for 48%) of Hongya camphor, 0.5 part by mass of borneol extract (dextroborneol accounts for 75%), 60 parts by mass of camphor leaf pure dew of Hongya camphor and 3 parts by mass of polyoxyethylene hydrogenated castor oil are mixed uniformly to obtain a mixture, so that the camphor leaf essential oil and the borneol extract of the Hongya camphor are fully dissolved in the camphor leaf pure dew of the Hongya camphor, then the mixture is added with 1 part by mass of rhizoma bletillae extract, 0.4 part by mass of poria cocos extract and 2 parts by mass of glycerol under the stirring state to obtain wet tissue immersion liquid, and then the non-woven fabric is immersed in the wet tissue immersion liquid, wherein the mass ratio of the non-woven fabric to the wet tissue immersion liquid is 2: 1.
Example 3
A preparation method of wet tissue comprises the following steps:
0.5 part by mass of camphor leaf essential oil (eucalyptol accounts for 50%) of Hongya camphor, 0.5 part by mass of borneol extract (dextroborneol accounts for 75%), 65 parts by mass of camphor leaf hydrosol of Hongya camphor and 4 parts by mass of polyoxyethylene hydrogenated castor oil are mixed uniformly to obtain a mixture, so that the camphor leaf essential oil and the borneol extract of the Hongya camphor are fully dissolved in the camphor leaf hydrosol of the Hongya camphor, then 2 parts by mass of rhizoma bletillae extract, 0.4 part by mass of poria cocos extract and 2 parts by mass of glycerol are added into the mixture under stirring to obtain wet tissue immersion liquid, and then the non-woven fabric is immersed into the wet tissue immersion liquid, wherein the mass ratio of the non-woven fabric to the wet tissue immersion liquid is 2: 1.
Example 4
A preparation method of wet tissue comprises the following steps:
0.5 part by mass of camphor leaf essential oil (eucalyptol accounts for 50%) of Hongya camphor, 0.5 part by mass of borneol extract (dextroborneol accounts for 75%), 45 parts by mass of camphor leaf pure dew of Hongya camphor and 6 parts by mass of polyoxyethylene hydrogenated castor oil are mixed uniformly to obtain a mixture, so that the camphor leaf essential oil and the borneol extract of the Hongya camphor are fully dissolved in the camphor leaf pure dew of the Hongya camphor, then 2 parts by mass of rhizoma bletillae extract, 0.4 part by mass of poria cocos extract and 2 parts by mass of glycerol are added into the mixture under the stirring state to be stirred uniformly to obtain wet tissue immersion liquid, and then a high-permeability polyethylene film (porosity is 75%) is immersed into the wet tissue immersion liquid, wherein the mass ratio of the high-permeability polyethylene film to the wet tissue immersion liquid is 2: 1.
Comparative example 1
A preparation method of wet tissue comprises the following steps:
uniformly mixing 0.5 part by mass of borneol extract (70% of D-borneol) and 60 parts by mass of camphor leaf pure dew of Hongya camphor to obtain wet tissue immersion liquid, and immersing non-woven fabrics into the wet tissue immersion liquid, wherein the mass ratio of the non-woven fabrics to the wet tissue immersion liquid is 2: 1.
Comparative example 2
A preparation method of wet tissue comprises the following steps:
0.4 part by mass of camphor leaf essential oil (eucalyptol accounts for 48%) of cinnamomum camphora and 60 parts by mass of camphor leaf pure dew of cinnamomum camphora to obtain wet tissue immersion liquid, and immersing non-woven fabric into the wet tissue immersion liquid, wherein the mass ratio of the non-woven fabric to the wet tissue immersion liquid is 2: 1.
Comparative example 3
A preparation method of wet tissue comprises the following steps:
0.4 part by mass of camphor leaf essential oil (eucalyptol accounts for 48%) of cinnamomum camphora, 0.5 part by mass of borneol extract (dextroborneol accounts for 70%) and 60 parts by mass of water are mixed uniformly to obtain wet tissue immersion liquid, and then non-woven fabrics are immersed into the wet tissue immersion liquid, wherein the mass ratio of the non-woven fabrics to the wet tissue immersion liquid is 2: 1.
Comparative example 4
A preparation method of wet tissue comprises the following steps:
0.1 part by mass of camphor leaf essential oil (eucalyptol accounts for 48%) of Hongya camphor, 3 parts by mass of borneol extract (D-borneol accounts for 70%) and 60 parts by mass of camphor leaf pure dew of Hongya camphor are uniformly mixed to obtain wet tissue immersion liquid, and then nonwoven fabric is immersed into the wet tissue immersion liquid, wherein the mass ratio of the nonwoven fabric to the wet tissue immersion liquid is 2: 1.
Performance test 1:
the wet tissues of examples 1-4 and comparative examples 1-4 were tested for antibacterial rate with action time of 5 minutes according to appendix C of product bactericidal performance, bacteriostatic performance and stability test method of GB15979-2002 hygienic disposable hygienic products hygienic Standard. The results are shown in Table 1.
TABLE 1
Figure BDA0001898846920000121
As can be seen from table 1, the wet towel of example 4 has the best antibacterial effect, and the wet towel base material used in example 4 is a high-permeability polyethylene film, which can release more wet towel immersion liquid than the wet towel base material used in example 3. The comparative example 1 has a poor antibacterial effect compared with the wet tissue of example 1, mainly because the essential oil of camphor leaves of cinnamomum camphora, which is an important component in the immersion fluid of the wet tissue, is lost, the antibacterial effect is poor, and particularly, the antibacterial rate of gram-negative bacteria such as escherichia coli is only 81.7%, so that the antibacterial requirement can not be met. Compared with the wet tissue in the example 1, the wet tissue in the comparative example 2 has poor antibacterial effect mainly because the important component borneol extract in the wet tissue immersion liquid is absent, and the antibacterial effect is poor, particularly the antibacterial rate to gram-positive bacteria such as bacillus subtilis and staphylococcus aureus is very low, so that the antibacterial requirement can not be met. Comparative example 3 is inferior to the wet tissue of example 1 in antibacterial effect, mainly because it lacks the camphor leaves hydrolat of the cinnamomum japonicum contained in the wet tissue immersion liquid, and uses water as a substitute, but does not contain minerals in the natural hydrolat, and cannot provide an internal environment for trans-membrane transportation of eucalyptol and d-borneol, and the antibacterial effect is greatly reduced. Comparative example 4 although the camphor leaf essence oil of cinnamomum japonicum and the camphor leaf of cinnamomum japonicum contained the borneol extract, the camphor leaf essence oil of cinnamomum japonicum and the camphor leaf of cinnamomum japonicum were contained, the ratio relationship of the three components was not in the range of the component ratio of the present invention, and the antibacterial effect was inferior to that of example 1.
Performance test 2:
mosquito bite detumescence test
(1) Test grouping
Subjects whose arms were bitten by aedes albopictus were grouped according to examples 1-4 and comparative examples 1-4, 10 persons each.
(2) Test method
The antibacterial skin-care wet tissues prepared in the examples and the comparative examples are used for wiping the affected part bitten by aedes albopictus, then the antibacterial skin-care wet tissues are applied to the affected part for about 120s, and the antibacterial skin-care wet tissues are continuously and lightly tapped to enable the wet tissue immersion liquid to fully permeate into the affected part. Comprehensive scoring is carried out by adopting a civil survey scoring method, and a trial scoring table is filled immediately after 120s (each group of subjects is averaged). The using effect of each item in the scoring table is divided into 5 points in total, 5 points are the highest points, which shows that the product is very satisfactory, the red and swollen wound is obviously relieved after the product is used, no itch and pain exist, and no other adverse skin reactions occur; 3, the medicine is better and relatively satisfactory, after the medicine is used, the red swelling is partially resolved, the skin feels slightly itchy and painful, other skin adverse reactions are not caused, but the medicine can be tolerated, and other skin adverse reactions are not caused; the content of 3 points below is unacceptable, and the wound is not red and swollen and feels itchy and painful. The average score of each use effect is shown in table 2:
TABLE 2
Figure BDA0001898846920000131
Figure BDA0001898846920000141
As can be seen from table 2, each example group had very good detumescence and antipruritic effects on wounds after mosquito bites, compared to each comparative group, wherein 9 subjects in example 4 scored up to 5 points. Scores below grade 3 were found in all of the groups of comparative examples 2-4. In addition, the subjects in the groups of examples 2-4, who were applied three consecutive times, had a significant healing effect on scratch-infected wounds.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. An antibacterial skin-care wet tissue, which is characterized by comprising: the wet tissue base material and the wet tissue immersion liquid comprise the following components in parts by mass:
0.2-1 part of camphor leaf essential oil of cinnamomum hongeuense camphor;
0.2-1 part of borneol extract;
60-70 parts of camphor leaf hydrolat of cinnamomum hongeucalypti camphor;
1-3 parts of bletilla striata extract;
0.2-1 part of tuckahoe extract;
2-10 parts of a humectant;
1-6 parts of a surfactant;
the mass of the D-borneol in the borneol extract accounts for 75 percent of the mass of the borneol extract;
the mass of the cineole in the camphor leaf essential oil accounts for 45-50% of the mass of the camphor leaf essential oil;
the mass ratio of the wet tissue base material to the wet tissue immersion liquid is more than 1.8: 1.
2. The antiseptic skin care wet wipe as set forth in claim 1, wherein the surfactant is selected from one or more of polyoxyethylene hydrogenated castor oil, polyoxyethylene lauryl ether, and polysorbate.
3. The antiseptic skin care wet wipe as set forth in claim 1, wherein the humectant is selected from one or both of glycerin and propylene glycol.
4. The antibacterial skin-care wet tissue as claimed in claim 1, wherein the mass ratio of the wet tissue base material to the wet tissue immersion liquid is 2:1-3: 1.
5. The antibacterial skin-care wet tissue as claimed in claim 1, wherein the wet tissue substrate is selected from non-woven fabric, fiber paper or a high-permeability polyethylene film.
6. The antibacterial skin-care wet tissue as claimed in claim 5, wherein the mass ratio of the high-permeability polyethylene film to the wet tissue immersion liquid is 2.5: 1.
7. The antibacterial skin-care wet tissue as claimed in claim 1, which is characterized by being prepared from a wet tissue base material and a wet tissue immersion liquid in a mass ratio of 2:1, wherein the wet tissue base material is non-woven fabric, and the wet tissue immersion liquid is composed of the following components in parts by mass:
0.4 part of camphor leaf essential oil of cinnamomum hongeucalypti camphor;
0.5 part of borneol extract;
60 parts of camphor leaf hydrolat of cinnamomum hongeucalypti camphor;
1 part of bletilla striata extract;
0.4 part of tuckahoe extract;
2 parts of glycerol;
3 parts of polyoxyethylene hydrogenated castor oil;
the mass of the D-borneol in the borneol extract accounts for 75 percent of the mass of the borneol extract;
the mass of the cineole in the camphor leaf essential oil accounts for 48 percent of the mass of the camphor leaf essential oil.
8. The antibacterial skin-care wet tissue as claimed in claim 1, which is characterized by being prepared from a wet tissue base material and a wet tissue immersion liquid in a mass ratio of 2:1, wherein the wet tissue base material is non-woven fabric, and the wet tissue immersion liquid is composed of the following components in parts by mass:
0.5 part of camphor leaf essential oil of cinnamomum hongeucalypti camphor;
0.5 part of borneol extract;
65 parts of camphor leaf hydrolat of cinnamomum hongeucalypti camphor;
2 parts of bletilla striata extract;
0.4 part of tuckahoe extract;
2 parts of glycerol;
4 parts of polyoxyethylene hydrogenated castor oil;
the mass of the D-borneol in the borneol extract accounts for 75 percent of the mass of the borneol extract;
the mass of the cineole in the camphor leaf essential oil accounts for 48 percent of the mass of the camphor leaf essential oil.
9. A method for preparing an antibacterial skin-care wet wipe as claimed in any one of claims 1 to 8, which comprises the steps of: uniformly mixing 0.2-1 part by mass of camphor leaf essential oil of Hongya camphor, 0.2-1 part by mass of borneol extract and 40-50 parts by mass of camphor leaf hydrosol of Hongya camphor to obtain wet tissue immersion liquid, and immersing a wet tissue base material into the wet tissue immersion liquid.
10. The method for preparing the antibacterial skin-care wet tissue as claimed in claim 9, wherein the preparation of the wet tissue immersion liquid comprises the following steps: firstly, 0.2-1 part by mass of camphor leaf essential oil of Hongya camphor, 0.2-1 part by mass of borneol extract, 60-70 parts by mass of camphor leaf hydrolat of Hongya camphor and 1-6 parts by mass of surfactant are uniformly mixed to obtain a mixture, 1-3 parts by mass of bletilla extract, 0.2-1 part by mass of poria extract and 2-10 parts by mass of humectant are added into the mixture under the stirring state, and the mixture is uniformly stirred to obtain wet tissue immersion liquid.
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