CN109820772A - Antibiotic skin-care wet tissue and preparation method thereof - Google Patents
Antibiotic skin-care wet tissue and preparation method thereof Download PDFInfo
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- CN109820772A CN109820772A CN201811503581.5A CN201811503581A CN109820772A CN 109820772 A CN109820772 A CN 109820772A CN 201811503581 A CN201811503581 A CN 201811503581A CN 109820772 A CN109820772 A CN 109820772A
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- camphor tree
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- 230000003115 biocidal effect Effects 0.000 title claims abstract description 41
- 238000002360 preparation method Methods 0.000 title claims abstract description 26
- 241000723346 Cinnamomum camphora Species 0.000 claims abstract description 164
- 238000007654 immersion Methods 0.000 claims abstract description 77
- 239000000284 extract Substances 0.000 claims abstract description 72
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 47
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- 239000000341 volatile oil Substances 0.000 claims abstract description 47
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- MKYBYDHXWVHEJW-UHFFFAOYSA-N N-[1-oxo-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propan-2-yl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(C(C)NC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 MKYBYDHXWVHEJW-UHFFFAOYSA-N 0.000 description 2
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- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 description 1
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of antibiotic skin-care wet tissues and preparation method thereof, the antibiotic skin-care wet tissue includes wet tissue substrate and wet paper immersion, and the wet paper immersion includes the component of following mass parts: 60-70 parts of camphor tree leaf hydrosol of 0.2-1 parts of 0.2-1 parts of camphor tree leaf essential oil, the borneol extract of big vast eucalyptus camphor tree and big vast eucalyptus camphor tree.Proportion relation in above-mentioned antibiotic skin-care wet tissue comprising natural plant extracts each component is reasonable, does not stimulate skin mildly.Above-mentioned antibiotic skin-care wet tissue is in addition to having conventional antibiotic skin-care function, the effect of red swelling of the skin after can also alleviating bite by mosquitos, skin itch.
Description
Technical field
The present invention relates to wet tissue technical fields, more particularly to a kind of antibiotic skin-care wet tissue and preparation method thereof.
Background technique
Wet tissue is to select high osmosis substrate, and disposable cleaning amenities is made through folding, humidification, packaging, is had clear
Clean, moisturizing skin basic function and it is easy to carry the features such as, become essential Clean- in people's daily life
Product.Wet tissue is usually to be made of substrate and medical fluid two parts.Although there are some wet tissues with antibacterial effect in the market,
Its raw material is complicated, and preparation, extraction process are cumbersome, and higher cost limits its use scope, it is even more important that these wet tissues
In usually using methylisothiazolinone, the chemical bactericides such as methylchloroisothiazandnone, such chemical bactericide medium poison
Property, it is irritant, exist using security risk.In addition, being usually added into wet tissue highly concentrated to improve the antibiotic property of wet tissue
The ethyl alcohol of degree, but concentration of alcohol is more than 60%, it may appear that and skin surface sebum dissolves excessive phenomenon, causes to have dry skin,
Allergic reaction is even resulted in, for sensitive skin, usually causes the allergic reactions such as fash, erythema.
Summary of the invention
Based on this, a kind of antibiotic skin-care wet tissue and preparation method thereof containing natural extract component is provided.
A kind of antibiotic skin-care wet tissue, the antibiotic skin-care wet tissue include: wet tissue substrate and wet paper immersion, the wet tissue leaching
Liquid includes the component of following mass parts:
0.2-1 parts of the camphor tree leaf essential oil of big vast eucalyptus camphor tree
0.2-1 parts of borneol extract and
60-70 parts of the camphor tree leaf hydrosol of big vast eucalyptus camphor tree.
Proportion relation in above-mentioned antibiotic skin-care wet tissue comprising natural plant extracts each component is reasonable, does not stimulate mildly
Skin.Above-mentioned antibiotic skin-care wet tissue is in addition to having conventional skin-protecting function, also with the skin after antibacterial and alleviation bite by mosquitos
The effect of redness, skin itch.Specifically, the d-Bomeol in borneol extract has antibacterial, inducing resuscitation of having one's ideas straightened out, it is refrigerant to stop
Bitterly.Cineole in the camphor tree leaf essential oil of big vast eucalyptus camphor tree has the function of warding off foul, antipruritic, swelling and pain relieving, especially sting to mosquito
There are obvious detumescence, itching-relieving efficacies in affected part after stinging.And camphor tree leaf essential oil inhibits to by the Gram-negative bacteria of representative of Escherichia coli
Effect is good.In the camphor tree leaf hydrosol of big vast eucalyptus camphor tree be rich in mineral ion, big vast eucalyptus camphor tree camphor tree leaf hydrosol provide rich in minerals from
Under the microenvironment of son, transported in keratoderma by way of transdermal delivery conducive to cineole and d-Bomeol, in turn
Go deep into affected part and carries out antibacterial, anti-inflammatory.In addition, cineole or natural preservative, can prevent wet tissue substrate due to length
Phase impregnates and breeds bacterium.
The quality of d-Bomeol accounts for the borneol extract in the borneol extract in one of the embodiments,
Quality is 70% or more.
The cineole quality in the camphor tree leaf essential oil accounts for the camphor tree leaf essential oil quality and is in one of the embodiments,
45%-50%.
The wet paper immersion further includes Pseudobulbus Bletillae (Rhizoma Bletillae) extract and tuckahoe extracts in one of the embodiments,.
In one of the embodiments, in parts by mass, described Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1-3 parts, the tuckahoe extracts 0.2-
1 part.
The mass ratio of the wet tissue substrate and the wet paper immersion is greater than 1.8:1 in one of the embodiments,.
The wet paper immersion further includes one of moisturizer and surfactant or two in one of the embodiments,
Kind.
The wet paper immersion includes moisturizer and surfactant, in parts by mass, institute in one of the embodiments,
State that moisturizer is 2-10 parts, the surfactant is 1-6 parts.
The present invention also provides a kind of preparation methods of antibiotic skin-care wet tissue.
A kind of preparation method of antibiotic skin-care wet tissue comprising following steps: first by the camphor tree leaf essential oil 0.2-1 of big vast eucalyptus camphor tree
The camphor tree leaf hydrosol 60-70 mass parts of mass parts, borneol extract 0.2-1 mass parts and Hong An camphor tree are uniformly mixed so as to obtain wet paper immersion,
Then wet tissue substrate is immersed in the wet paper immersion.
The preparation method of above-mentioned antibiotic skin-care wet tissue is simple, does not add chemically synthesized antibacterial agent, the wet tissue being prepared
In addition to having conventional antibacterial functions, the effect of red swelling of the skin after bite by mosquitos can also be alleviated, skin itch.
The preparation of the wet paper immersion includes the following steps: the first camphor tree leaf essence by big vast eucalyptus camphor tree in one of the embodiments,
Oily 0.2-1 mass parts, borneol extract 0.2-1 mass parts, the camphor tree leaf hydrosol 60-70 mass parts and surfactant of big vast eucalyptus camphor tree
1-6 mass parts are uniformly mixed so as to obtain mixture, and Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1-3 mass parts are added under stirring in the mixture, Poria cocos mentions
Object 0.2-1 mass parts, moisturizer 2-10 mass parts are taken, wet paper immersion is uniformly mixing to obtain.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, below to specific reality of the invention
The mode of applying is described in detail.In the following description, numerous specific details are set forth in order to facilitate a full understanding of the present invention.But
The invention can be embodied in many other ways as described herein, and those skilled in the art can be without prejudice to originally
Similar improvement is done in the case where invention intension, therefore the present invention is not limited by the specific embodiments disclosed below.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention
The normally understood meaning of technical staff it is identical.Term as used herein in the specification of the present invention is intended merely to retouch
State the purpose of specific embodiment, it is not intended that in the limitation present invention.Term " and or " used herein include one or
Any and all combinations of multiple relevant listed items.
A kind of antibiotic skin-care wet tissue is provided in one embodiment of the invention comprising: wet tissue substrate and wet paper immersion, institute
State the component that wet paper immersion includes following mass parts:
0.2-1 parts of the camphor tree leaf essential oil of big vast eucalyptus camphor tree
0.2-1 parts of borneol extract and
60-70 parts of the camphor tree leaf hydrosol of big vast eucalyptus camphor tree.
The selection of wet tissue substrate can without limitation, such as selected from non-woven fabrics, fibrous paper or hypertonic polyethylene film.It is fine
Tieing up paper can be bamboo fibre paper or wood-fibred paper, or bamboo fibre paper and wood-fibred paper mixed pulp according to a certain percentage
Obtained compound wet tissue substrate, it is preferable that the mass ratio of bamboo fibre paper and wood-fibred paper is 1:1-1:2, it will be understood that bamboo is fine
The mass ratio for tieing up paper and wood-fibred paper can be 1:1, and bamboo fibre paper and the mass ratio of wood-fibred paper may be 1:2, most preferably
, the mass ratio of bamboo fibre paper and wood-fibred paper is 1:1.5.When selecting hypertonic polyethylene film such as wet tissue substrate, wet paper immersion
The hole that polyethylene film can preferably be penetrated is entered inside it, for traditional non-woven fabrics, absorbs medical fluid more
It is more, it when needing to treat or alleviate the affected part of the redness after bite by mosquitos, pain of itching, can gently pat, the wet tissue back side, absorb
Wet paper immersion can be fast extruded in affected part, treated.Preferably, selecting porosity is the height of 70%-80%
Polyethylene film is seeped as wet tissue substrate.
The mass ratio of the wet tissue substrate and the wet paper immersion is greater than 1.7:1 in one of the embodiments,.
The mass ratio of the wet tissue substrate and the wet paper immersion is 2:1-3:1 in one of the embodiments,.It is preferred that
The mass ratio of ground, the hypertonic polyethylene film and the wet paper immersion is 2.5:1.
Big vast eucalyptus camphor tree is Lauraceae Cinnamomum aiphyllium tree species, is rich in camphor tree leaf essential oil in big vast eucalyptus camphor tree leaf piece, is extracted by cultivation
Essential oil is widely used in the industries such as medicine, flavors and fragrances and cosmetics, has a vast market foreground.The camphor tree leaf essence of big vast eucalyptus camphor tree
Oily main active is cineole, and cineole has the function of warding off foul, antipruritic, swelling and pain relieving, especially to mosquito
There are obvious detumescence, itching-relieving efficacies in affected part after biting.Present inventor has found that cineole can be representative to Escherichia coli
Gram-negative bacteria have good inhibiting effect.In addition, also containing days such as amphene, firpenes in the camphor tree leaf essential oil of big vast eucalyptus camphor tree
Right fragrance component can bring natural herbal medicine fragrance for wet tissue, pleasant feeling is brought while refreshing the mind.
The cineole quality in the camphor tree leaf essential oil of the big vast eucalyptus camphor tree accounts for the big vast eucalyptus camphor tree in one of the embodiments,
Camphor tree leaf essential oil quality be 45%-50%.The fungistatic effect of antibiotic skin-care wet tissue can be further enhanced.Preferably, the flood
The quality that the quality of cineole in the camphor tree leaf essential oil of eucalyptus camphor tree accounts for the camphor tree leaf essential oil of the big vast eucalyptus camphor tree is 48%.
Wherein, effective component is mainly d-Bomeol in borneol extract, and d-Bomeol has antibacterial, inducing resuscitation of having one's ideas straightened out, clear
Cool analgesic, the effect of mosquito repellent.
The quality of the d-Bomeol in the borneol extract accounts for the borneol extract in one of the embodiments,
Quality be 70% or more.The fungistatic effect of antibiotic skin-care wet tissue can be further enhanced.Preferably, the borneol extract
In d-Bomeol quality account for the borneol extract quality be 75% or more, further, in the borneol extract
The quality that the quality of d-Bomeol accounts for the borneol extract is 75%-95%.
Wherein, it is rich in mineral ion in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree of the invention, is provided in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree
The microenvironment rich in mineral ion under, skin is transported by way of transdermal delivery conducive to cineole and d-Bomeol
In skin cuticula, and then gos deep into affected part and carry out antibacterial, anti-inflammatory.That is, the camphor tree leaf hydrosol of big vast eucalyptus camphor tree provides and is conducive to effectively
Substance enters the microenvironment channel in skin affected part.
The wet paper immersion further includes Pseudobulbus Bletillae (Rhizoma Bletillae) extract and tuckahoe extracts in one of the embodiments,.
Pseudobulbus Bletillae (Rhizoma Bletillae) extract mainly has effects that detumescence and promoting granulation, convergence, especially with bacillus subtilis, golden yellow Portugal
These Gram-negative bacterias of grape coccus, Candida albicans have good inhibiting effect.In addition, containing natural in Pseudobulbus Bletillae (Rhizoma Bletillae) extract
Bletilla glue ingredient, the ingredient of the nourishes rough skins such as compound a large amount of vitamins, amino acid, long-time service can enhance skin elasticity and
It is compact.It is natural skin conditioner.
Tuckahoe extracts main function is to improve skin injury, is had particularly with because of the damaged skin histology of odd oxygen scratching
Good repair, and preventing from scar adjust the balance of environment in skin.
In one of the embodiments, in parts by mass, described Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1-3 parts, the tuckahoe extracts 0.2-
1 part.
The wet paper immersion includes the component of following mass parts in one of the embodiments:
The wet paper immersion further includes one of moisturizer and surfactant or two in one of the embodiments,
Preferably, the wet paper immersion includes the combination of both moisturizer and surfactant.In parts by mass, the moisturizer is
2-10 parts, surfactant be 1-6 parts.
Surfactant main function is dirt and grease in one of the embodiments, plays cleaning action, this
Outside, surfactant additionally aids the solubility for increasing the camphor tree leaf essential oil of big vast eucalyptus camphor tree, as taken before surfactant is not used
A certain amount of camphor tree leaf essential oil is dissolved in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree, solubility of the camphor tree leaf essential oil in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree
For 0.3mg/mL, after surfactant is added, solubility of the camphor tree leaf essential oil in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree is increased to 0.5mg/
mL.Furthermore surfactant can also adjust oil-phase component and water-phase component compatibility in wet paper immersion, interface surface is reduced
Tension, improve the stability of wet paper immersion, prevent the precipitation of effective component camphor tree leaf essential oil, borneol extract.
Surfactant is selected from Crodaret, lauryl alcohol polyethylene glycol oxide in one of the embodiments,
One of ether, polysorbate are a variety of, such as: surfactant is selected from Crodaret, polyethylene glycol hydrogenated
Castor oil and ethoxylated dodecyl alcohol.
Moisturizer is selected from one or both of glycerol or propylene glycol in one of the embodiments,.
It is appreciated that the wet paper immersion in the present invention can also include preservative, it is described to extend the storage life of wet tissue
Preservative is selected from one of benzoic acid or Phenoxyethanol.
The wet paper immersion includes the component of following mass parts in one of the embodiments:
Proportion relation in above-mentioned antibiotic skin-care wet tissue comprising natural plant extracts each component is reasonable, does not stimulate mildly
Skin.Above-mentioned antibiotic skin-care wet tissue is in addition to having conventional skin-protecting function, also with the skin after antibacterial and alleviation bite by mosquitos
The effect of redness, skin itch.Specifically, the d-Bomeol in borneol extract has antibacterial, inducing resuscitation of having one's ideas straightened out, it is refrigerant to stop
Bitterly.Cineole in the camphor tree leaf essential oil of big vast eucalyptus camphor tree has the function of warding off foul, antipruritic, swelling and pain relieving, especially sting to mosquito
There are obvious detumescence, itching-relieving efficacies in affected part after stinging.And camphor tree leaf essential oil inhibits to by the Gram-negative bacteria of representative of Escherichia coli
Effect is good.In the camphor tree leaf hydrosol of big vast eucalyptus camphor tree be rich in mineral ion, big vast eucalyptus camphor tree camphor tree leaf hydrosol provide rich in minerals from
Under the microenvironment of son, transported in keratoderma by way of transdermal delivery conducive to cineole and d-Bomeol, in turn
Go deep into affected part and carries out antibacterial, anti-inflammatory.In addition, cineole or natural preservative, can prevent wet tissue substrate due to length
Phase impregnates and breeds bacterium.
The present invention also provides a kind of preparation method of antibiotic skin-care wet tissue,
A kind of preparation method of antibiotic skin-care wet tissue comprising following steps: first by the camphor tree leaf essential oil 0.2-1 of big vast eucalyptus camphor tree
The camphor tree leaf hydrosol 60-70 mass parts of mass parts, borneol extract 0.2-1 mass parts and Hong An camphor tree are uniformly mixed so as to obtain wet paper immersion,
Then wet tissue substrate is immersed in the wet paper immersion.
The time that wet tissue substrate immerses wet paper immersion in one of the embodiments, is 30min-60min, so that wet tissue
Substrate fully absorbs wet paper immersion swelling.
The preparation of the wet paper immersion includes the following steps: the first camphor tree leaf essence by big vast eucalyptus camphor tree in one of the embodiments,
Oily 0.2-1 mass parts, borneol extract 0.2-1 mass parts, the camphor tree leaf hydrosol 60-70 mass parts and surfactant of big vast eucalyptus camphor tree
1-6 mass parts are uniformly mixed so as to obtain mixture, and Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1-3 mass parts are added under stirring in the mixture, Poria cocos mentions
Object 0.2-1 mass parts, moisturizer 2-10 mass parts are taken to be uniformly mixing to obtain wet paper immersion.
The preparation method of antibiotic skin-care wet tissue includes the following steps: the camphor tree leaf of big vast eucalyptus camphor tree in one of the embodiments,
Essential oil 0.2-1 mass parts, borneol extract 0.2-1 mass parts, the camphor tree leaf hydrosol 60-70 mass parts and surface-active of big vast eucalyptus camphor tree
Agent 1-6 mass parts mix, so that camphor tree leaf essential oil, the borneol extract of big vast eucalyptus camphor tree are substantially soluble in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree and obtain
To mixture, wherein the camphor tree leaf that camphor tree leaf essential oil, the borneol extract that surfactant is conducive to big vast eucalyptus camphor tree are dissolved in big vast eucalyptus camphor tree is pure
In dew.Then Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1-3 mass parts are added under stirring, tuckahoe extracts 0.2-1 mass parts, protect for mixture
Humectant 2-10 mass parts are uniformly mixing to obtain wet paper immersion, then wet tissue substrate are immersed in the wet paper immersion, the wet tissue base
The mass ratio of material and the wet paper immersion is greater than 1.8:1.
The preparation method of antibiotic skin-care wet tissue includes the following steps: the camphor tree leaf of big vast eucalyptus camphor tree in one of the embodiments,
0.4 mass parts of essential oil, 0.4 mass parts of borneol extract, 3 mass of 45 mass parts of camphor tree leaf hydrosol and surfactant of big vast eucalyptus camphor tree
Part mixes, so that camphor tree leaf essential oil, the borneol extract of big vast eucalyptus camphor tree are substantially soluble in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree and obtain mixture,
Wherein, camphor tree leaf essential oil, the borneol extract that surfactant is conducive to big vast eucalyptus camphor tree are dissolved in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree.Then
2 mass parts of Pseudobulbus Bletillae (Rhizoma Bletillae) extract, 0.5 mass parts of tuckahoe extracts, 4 mass parts of moisturizer are added under stirring and stir for mixture
It mixes and uniformly obtains wet paper immersion, then wet tissue substrate is immersed in the wet paper immersion, the wet tissue substrate and the wet paper immersion
Mass ratio be 2.5:1.
The preparation method of above-mentioned antibiotic skin-care wet tissue is simple, does not add chemically synthesized antibacterial agent, the wet tissue being prepared
In addition to having conventional antibacterial functions, the effect of red swelling of the skin after bite by mosquitos can also be alleviated, skin itch.
In order to which objects and advantages of the present invention are more clearly understood, the present invention is carried out into one with reference to embodiments
Step is described in detail.It should be appreciated that described herein, specific examples are only used to explain the present invention, is not used to limit this hair
It is bright.
Embodiment 1
A kind of preparation method of wet tissue, includes the following steps:
By 0.4 mass parts of camphor tree leaf essential oil (cineole accounts for 43%) of big vast eucalyptus camphor tree, the 0.5 mass parts (dextrorotation of borneol extract
Borneol account for 70%), 60 mass parts of camphor tree leaf hydrosol of big vast eucalyptus camphor tree be uniformly mixed so as to obtain wet paper immersion so that the camphor tree leaf essential oil of big vast eucalyptus camphor tree, dragon
Brain extract is substantially soluble in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree, then non-woven fabrics is immersed in wet paper immersion, non-woven fabrics and wet paper immersion
Mass ratio be 2:1.
Embodiment 2
A kind of preparation method of wet tissue, includes the following steps:
By 0.4 mass parts of camphor tree leaf essential oil (cineole accounts for 48%) of big vast eucalyptus camphor tree, the 0.5 mass parts (dextrorotation of borneol extract
Borneol account for 75%), 60 mass parts of camphor tree leaf hydrosol of big vast eucalyptus camphor tree are uniformly mixed so as to obtain with 3 mass parts of Crodaret and mix
Object, so that camphor tree leaf essential oil, the borneol extract of big vast eucalyptus camphor tree are substantially soluble in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree, then mixture is being stirred
Mix and 1 mass parts of Pseudobulbus Bletillae (Rhizoma Bletillae) extract be added under state, 0.4 mass parts of tuckahoe extracts, 2 mass parts of glycerol be uniformly mixing to obtain it is wet
Towel immersion liquid, then non-woven fabrics is immersed in wet paper immersion, the mass ratio of non-woven fabrics and wet paper immersion is 2:1.
Embodiment 3
A kind of preparation method of wet tissue, includes the following steps:
By 0.5 mass parts of camphor tree leaf essential oil (cineole accounts for 50%) of big vast eucalyptus camphor tree, the 0.5 mass parts (dextrorotation of borneol extract
Borneol account for 75%), 65 mass parts of camphor tree leaf hydrosol of big vast eucalyptus camphor tree are uniformly mixed so as to obtain with 4 mass parts of Crodaret and mix
Object, so that camphor tree leaf essential oil, the borneol extract of big vast eucalyptus camphor tree are substantially soluble in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree, then mixture is being stirred
Mix and 2 mass parts of Pseudobulbus Bletillae (Rhizoma Bletillae) extract be added under state, 0.4 mass parts of tuckahoe extracts, 2 mass parts of glycerol be uniformly mixing to obtain it is wet
Towel immersion liquid, then non-woven fabrics is immersed in wet paper immersion, the mass ratio of non-woven fabrics and wet paper immersion is 2:1.
Embodiment 4
A kind of preparation method of wet tissue, includes the following steps:
By 0.5 mass parts of camphor tree leaf essential oil (cineole accounts for 50%) of big vast eucalyptus camphor tree, the 0.5 mass parts (dextrorotation of borneol extract
Borneol account for 75%), 45 mass parts of camphor tree leaf hydrosol of big vast eucalyptus camphor tree are uniformly mixed so as to obtain with 6 mass parts of Crodaret and mix
Object, so that camphor tree leaf essential oil, the borneol extract of big vast eucalyptus camphor tree are substantially soluble in the camphor tree leaf hydrosol of big vast eucalyptus camphor tree, then mixture is being stirred
Addition 2 mass parts of Pseudobulbus Bletillae (Rhizoma Bletillae) extract, 0.4 mass parts of tuckahoe extracts, 2 mass parts mass parts of glycerol under state are mixed to stir evenly
Obtain wet paper immersion, then hypertonic polyethylene film (porosity 75%) immersed in wet paper immersion, hypertonic polyethylene film with it is wet
The mass ratio of towel immersion liquid is 2:1.
Comparative example 1
A kind of preparation method of wet tissue, includes the following steps:
60 mass parts of camphor tree leaf hydrosol of 0.5 mass parts of borneol extract (d-Bomeol accounts for 70%), big vast eucalyptus camphor tree are mixed
It is immersed in wet paper immersion to wet paper immersion, then by non-woven fabrics, the mass ratio of non-woven fabrics and wet paper immersion is 2:1.
Comparative example 2
A kind of preparation method of wet tissue, includes the following steps:
By 60 mass of camphor tree leaf hydrosol of 0.4 mass parts of camphor tree leaf essential oil (cineole accounts for 48%) of big vast eucalyptus camphor tree and Hong An camphor tree
Part is uniformly mixed so as to obtain wet paper immersion, then non-woven fabrics is immersed in wet paper immersion, and the mass ratio of non-woven fabrics and wet paper immersion is 2:1.
Comparative example 3
A kind of preparation method of wet tissue, includes the following steps:
By 0.4 mass parts of camphor tree leaf essential oil (cineole accounts for 48%) of big vast eucalyptus camphor tree, the 0.5 mass parts (dextrorotation of borneol extract
Borneol account for 70%), 60 mass parts of water are uniformly mixed so as to obtain wet paper immersion, then non-woven fabrics are immersed in wet paper immersion, non-woven fabrics and wet tissue
The mass ratio of immersion liquid is 2:1.
Comparative example 4
A kind of preparation method of wet tissue, includes the following steps:
By 0.1 mass parts of camphor tree leaf essential oil (cineole accounts for 48%) of big vast eucalyptus camphor tree, 3 mass parts of borneol extract (dextrorotation dragon
Brain account for 70%), 60 mass parts of camphor tree leaf hydrosol of big vast eucalyptus camphor tree be uniformly mixed so as to obtain wet paper immersion, then non-woven fabrics immersed in wet paper immersion,
The mass ratio of non-woven fabrics and wet paper immersion is 2:1.
Performance test 1:
Referring to " GB15979-2002 disposable sanitary articles sanitary standard " appendix C " product bactericidal property, bacteriostasis property
With stability test method " antibiotic rate test is carried out to the wet tissue of embodiment 1-4 and comparative example 1-4, action time is 5 minutes.
It the results are shown in Table 1.
Table 1
As shown in Table 1, the wet tissue antibacterial effect of embodiment 4 is best, the wet tissue base that embodiment 4 is used relative to embodiment 3
Material is hypertonic polyethylene film, can discharge more wet paper immersions.Wet tissue antibacterial effect of the comparative example 1 relative to embodiment 1
Difference, mainly because of the camphor tree leaf essential oil that it lacks the important component flood eucalyptus camphor tree in wet paper immersion, fungistatic effect is poor, especially to big
The bacteriostasis rate of this kind of Gram-negative bacteria of enterobacteria is only 81.7%, is far from satisfying antibacterial demand.Comparative example 2 relative to
The wet tissue antibacterial effect of embodiment 1 is poor, mainly because it lacks the important component borneol extract in wet paper immersion, antibacterial effect
Fruit is poor, especially very low to the bacteriostasis rate of bacillus subtilis, this kind of gram-positive bacteria of staphylococcus aureus, much
It is not able to satisfy antibacterial demand.Comparative example 3 is poor relative to the wet tissue antibacterial effect of embodiment 1, and mainly it lacks wet paper immersion
In big vast eucalyptus camphor tree camphor tree leaf hydrosol, and with water alternatively, can not be eucalyptus still in water without the minerals in natural hydrosol
Leaf oil element and d-Bomeol provide the interior environment of transdermal delivery, and antibacterial effect is had a greatly reduced quality.Although comparative example 4 is mentioned containing borneol
The camphor tree leaf hydrosol of object, the camphor tree leaf essential oil of big vast eucalyptus camphor tree and Hong An camphor tree is taken, but proportions' relationship is not in component proportion of the invention
In range, antibacterial effect is poor relative to embodiment 1.
Performance test 2:
Bite by mosquitos detumescence test
(1) test grouping
The subject that arm is bitten by aedes albopictus is grouped according to embodiment 1-4, comparative example 1-4, every group 10
People.
(2) test method
The affected part bitten by aedes albopictus is wiped using the antibiotic skin-care wet tissue prepared in each embodiment, comparative example group, so
After spread on affected part 120s or so, and constantly gently pat antibiotic skin-care wet tissue so that wet paper immersion is fully infiltrated into affected part.Using the people
Meaning investigation point system carries out comprehensive score, fills in grade form on probation immediately after 120s (every group of subject makes even respectively).Grade form
Middle items using effect total score is 5 points, and 5 points are best result, indicates very satisfied, is subsided using rear wound redness is obvious, nothing is itched
Bitterly, do not occur other skin adverse reactions；3 points be it is preferable, relatively satisfied, redness has partial remission, slightly sense to itch after use
Bitterly, do not occur other skin adverse reactions, but can endure, do not occur other skin adverse reactions；3 points the following are can not connect
The range received, wound redness feel pain of itching without recession.Every using effect average situation is as shown in table 2:
Table 2
As shown in Table 2, each embodiment group relative to each comparative example group to the wound after bite by mosquitos have well detumescence,
Antipruritic effect, wherein the subject in embodiment 4 has up to 5 points of 9 people scoring.Occur in comparative example 2-4 group 3 grades with
Under scoring.In addition, the subject in embodiment 2-4 group continuously smears three times, there is apparent healing to the wound of scratching infection
Effect.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention
Protect range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (10)
1. a kind of antibiotic skin-care wet tissue, which is characterized in that the antibiotic skin-care wet tissue includes: wet tissue substrate and wet paper immersion, institute
State the component that wet paper immersion includes following mass parts:
0.2-1 parts of the camphor tree leaf essential oil of big vast eucalyptus camphor tree
0.2-1 parts of borneol extract and
60-70 parts of the camphor tree leaf hydrosol of big vast eucalyptus camphor tree.
2. antibiotic skin-care wet tissue according to claim 1, which is characterized in that the matter of d-Bomeol in the borneol extract
The quality that amount accounts for the borneol extract is 75% or more.
3. antibiotic skin-care wet tissue according to claim 1, which is characterized in that the cineole quality in the camphor tree leaf essential oil
Accounting for the camphor tree leaf essential oil quality is 45%-50%.
4. antibiotic skin-care wet tissue according to any one of claim 1 to 3, which is characterized in that the wet paper immersion also wraps
Include Pseudobulbus Bletillae (Rhizoma Bletillae) extract and tuckahoe extracts.
5. antibiotic skin-care wet tissue according to claim 4, which is characterized in that in parts by mass, the Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1-3
Part, it is tuckahoe extracts 0.2-1 parts described.
6. antibiotic skin-care wet tissue according to any one of claim 1 to 3, which is characterized in that the wet tissue substrate and institute
The mass ratio for stating wet paper immersion is greater than 1.8:1.
7. antibiotic skin-care wet tissue according to any one of claim 1 to 3, which is characterized in that the wet paper immersion also wraps
Include one or both of moisturizer and surfactant.
8. antibiotic skin-care wet tissue according to claim 7, which is characterized in that the wet paper immersion includes moisturizer and surface
Activating agent, in parts by mass, the moisturizer is 2-10 parts, surfactant is 1-6 parts.
9. a kind of preparation method of antibiotic skin-care wet tissue, which comprises the steps of: by the camphor tree leaf essential oil of big vast eucalyptus camphor tree
The camphor tree leaf hydrosol 40-50 mass parts of 0.2-1 mass parts, borneol extract 0.2-1 mass parts and Hong An camphor tree are uniformly mixed so as to obtain wet tissue
Immersion liquid, then wet tissue substrate is immersed in the wet paper immersion.
10. the preparation method of antibiotic skin-care wet tissue according to claim 9, which is characterized in that the system of the wet paper immersion
It is standby to include the following steps: the camphor tree leaf essential oil 0.2-1 mass parts of big vast eucalyptus camphor tree, borneol extract 0.2-1 mass parts, big vast eucalyptus camphor tree first
Camphor tree leaf hydrosol 60-70 mass parts and surfactant 1-6 mass parts are uniformly mixed so as to obtain mixture, and the mixture is under stirring
Pseudobulbus Bletillae (Rhizoma Bletillae) extract 1-3 mass parts, tuckahoe extracts 0.2-1 mass parts, moisturizer 2-10 mass parts are added, are uniformly mixing to obtain wet
Towel immersion liquid.
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