CN109725169B - Liquid path system of urine analyzer and control method thereof - Google Patents

Liquid path system of urine analyzer and control method thereof Download PDF

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Publication number
CN109725169B
CN109725169B CN201811603521.0A CN201811603521A CN109725169B CN 109725169 B CN109725169 B CN 109725169B CN 201811603521 A CN201811603521 A CN 201811603521A CN 109725169 B CN109725169 B CN 109725169B
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pipeline
sample
valve
controlling
communicating valve
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CN109725169A (en
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张鹏
张建
张庆贺
张彦月
于国庆
刘西宝
朱文强
邓宝
苏照洋
姜永水
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Dirui Medical Technology Co Ltd
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Dirui Medical Technology Co Ltd
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Abstract

The invention provides a liquid path system of a urine analyzer and an implementation method thereof, wherein the system comprises a sample sucking liquid path and a sample dripping liquid path, wherein the sample sucking liquid path comprises a sample sucking needle, a first communicating valve connected with the sample sucking needle through a first pipeline and a liquid sucking injector connected with the first communicating valve through a second pipeline; the sample dropping liquid path comprises a sample dropping needle, a second communicating valve connected with the sample dropping needle through a third pipeline and a dropping injector connected with the third pipeline through a fourth pipeline; and a fifth pipeline is connected between the first communicating valve and the second communicating valve. The liquid path system comprises a sample sucking liquid path and a sample dripping liquid path, can completely separate a sample sucking process and a sample dripping process in a test, and greatly improves the test speed because the sample sucking process and the sample dripping process are parallel.

Description

Liquid path system of urine analyzer and control method thereof
Technical Field
The invention relates to the field of urine analyzers, in particular to a liquid path system of a urine analyzer and a control method thereof.
Background
The urine analyzer is an instrument for measuring certain chemical components in urine, is an important tool for detecting urine samples in a medical laboratory, is subjected to multiple stages of manual operation, semi-automatic instruments and full-automatic instruments, and is increasingly popularized along with the high-speed development of the technology.
In large hospitals, urine tests are routine tests, with large daily sample volumes, typically in excess of 500 per day. The collection of such a large amount of samples needs to consume a large amount of time, and the collection needs to be carried out on a computer for detection after the completion, if the instrument testing speed is too slow, the time period from the collection to the detection of the samples often exceeds 3 hours, and some of the samples even exceed 4 hours, and the optimal testing time of the samples is generally within 2 hours after the samples are collected, at this time, the hospital often needs to improve the detection speed by increasing the number of the full-automatic urine instruments.
The current urine analyzer generally adopts a single-needle scheme, namely, one sample suction needle finishes sample suction, sample adding and cleaning, and the single-needle scheme is used for completing the test of a single sample and needs to perform the following steps: the sample suction needle moves to the sample suction position → the sample suction needle sucks the sample → the sample suction needle moves to the sample dripping position → the sample suction needle drips the sample → the sample suction needle moves to the cleaning position → the sample suction needle cleans the inner wall → the sample suction needle cleans the outer wall.
Accordingly, the prior art is yet to be improved and developed.
Disclosure of Invention
In view of the above-mentioned deficiencies of the prior art, the present invention aims to provide a liquid path system of a urine analyzer and a control method thereof, which aim to solve the technical problems that the existing urine analyzer is slow in testing speed, low in efficiency and incapable of meeting the requirement of high-speed testing.
The technical scheme of the invention is as follows:
a liquid path system of a urine analyzer comprises a sample sucking liquid path and a sample dropping liquid path, wherein the sample sucking liquid path comprises a sample sucking needle, a first communicating valve connected with the sample sucking needle through a first pipeline and a liquid suction injector connected with the first communicating valve through a second pipeline; the sample dripping liquid path comprises a sample dripping needle, a second communicating valve connected with the sample dripping needle through a third pipeline and a liquid dripping injector connected with the third pipeline through a fourth pipeline; and a fifth pipeline is connected between the first communicating valve and the second communicating valve.
The liquid path system, wherein, still include the washing liquid way, the washing liquid way is including wasing the pond, wash the pond through sixth pipeline with the second intercommunication valve links to each other, it has the washing syringe to wash the pond through seventh pipe connection, be provided with the third intercommunication valve on the seventh pipeline, the dropping liquid syringe pass through the eighth pipeline with the third intercommunication valve links to each other.
The liquid path system is characterized in that a fourth communicating valve is arranged on the second pipeline, the fourth communicating valve is connected with a fifth communicating valve through a ninth pipeline, the fifth communicating valve is connected with the fifth pipeline through a tenth pipeline, a sixth communicating valve is arranged on the seventh pipeline, the cleaning liquid path further comprises a cleaning agent groove, and the cleaning agent groove is connected with the fifth communicating valve and the sixth communicating valve through an eleventh pipeline and a twelfth pipeline respectively.
In the liquid path system, the first communicating valve, the second communicating valve, the third communicating valve, the fourth communicating valve, the fifth communicating valve and the sixth communicating valve are all three-way electromagnetic valves.
The liquid path system, wherein, imbibition syringe, dropping liquid syringe and washing syringe all drive through driving motor.
The liquid path system, wherein, wash the pond and have waste liquid groove through thirteenth pipe connection, be provided with the waste liquid pump on the thirteenth pipe connection.
The liquid path system, wherein, be provided with the filter on the first pipeline.
A control method of a liquid path system of a urine analyzer comprises the following steps:
and (3) a sample sucking process: controlling the sample sucking needle to move to a sample sucking position, controlling the first communicating valve and the fourth communicating valve to communicate the first pipeline and the second pipeline, controlling the piston of the liquid suction injector to descend for sample sucking, and sucking the sample to the second pipeline;
a sample separation process: controlling the first communicating valve to disconnect the first pipeline, controlling the first communicating valve and the second communicating valve to connect the second pipeline, the fifth pipeline and the third pipeline, and controlling the piston of the imbibition injector to ascend to transfer the sample in the second pipeline to the third pipeline and the fourth pipeline;
dropping the sample: and controlling the sample dripping needle to move above the detection test paper and controlling the second communication valve to disconnect the fifth pipeline, and controlling the piston of the sample dripping injector to ascend to drip the samples in the third pipeline and the fourth pipeline onto the detection test paper through the sample dripping needle.
The control method further comprises:
and (3) cleaning a sample sucking liquid path: controlling the first communicating valve and the fourth communicating valve to communicate the first pipeline and the second pipeline, controlling the third communicating valve and the fourth communicating valve to communicate the seventh pipeline, and controlling the piston of the imbibition syringe and the piston of the cleaning syringe to ascend to complete cleaning of the imbibition liquid channel;
and controlling the first connecting valve to break the first pipeline, controlling the second connecting valve to conduct the fifth pipeline and the sixth pipeline, controlling the fourth connecting valve and the fifth connecting valve to conduct the second pipeline, the ninth pipeline and the tenth pipeline, and controlling the piston of the imbibition syringe and the piston of the cleaning syringe to ascend to complete cleaning of the fifth pipeline.
The control method further comprises:
and (3) cleaning a sample dripping liquid path: and controlling the second communicating valve to conduct the third pipeline and the fifth pipeline, controlling the fourth communicating valve and the fifth communicating valve to conduct the second pipeline, the ninth pipeline and the tenth pipeline, controlling the third communicating valve and the sixth communicating valve to conduct the seventh pipeline and the eighth pipeline, controlling the piston of the imbibition syringe and the piston of the cleaning syringe to ascend, and completing cleaning of the sample dropping path.
Has the beneficial effects that: the invention provides a liquid path system of a urine analyzer and an implementation method thereof, wherein the system comprises a sample sucking liquid path and a sample dripping liquid path, wherein the sample sucking liquid path comprises a sample sucking needle, a first communicating valve connected with the sample sucking needle through a first pipeline and a liquid suction injector connected with the first communicating valve through a second pipeline; the sample dropping liquid path comprises a sample dropping needle, a second communicating valve connected with the sample dropping needle through a third pipeline and a dropping injector connected with the third pipeline through a fourth pipeline; and a fifth pipeline is connected between the first communicating valve and the second communicating valve. The liquid path system comprises the sample sucking liquid path and the sample dripping liquid path, can completely separate the sample sucking process and the sample dripping process in the test, and greatly improves the test speed because the sample sucking process and the sample dripping process are parallel.
Drawings
FIG. 1 is a schematic diagram of a fluid path system of a urine analyzer according to the present invention;
FIG. 2 is a schematic structural diagram of a sample aspirating path according to the present invention;
FIG. 3 is a schematic structural diagram of a sample dropping path according to the present invention;
FIG. 4 is a schematic diagram of a structure of a liquid path for cleaning a sample aspirating needle according to the present invention;
fig. 5 is a schematic structural diagram of a liquid path for cleaning a sample dropping needle according to the present invention.
Detailed Description
The invention provides a liquid path system of a urine analyzer and a control method thereof, and the invention is further explained in detail below in order to make the purpose, technical scheme and effect of the invention clearer and clearer. It should be understood that the specific embodiments described herein are merely illustrative of the invention and do not limit the invention.
Referring to fig. 1, the liquid path system of the urine analyzer provided by the present invention includes a sample sucking path and a sample dropping path, wherein the sample sucking path includes a sample sucking needle 10, a first communicating valve 30 connected to the sample sucking needle 10 through a first pipeline 20, and a liquid sucking syringe 50 connected to the first communicating valve 30 through a second pipeline 40; the sample dropping path includes a sample dropping needle 60, a second communicating valve 80 connected to the sample dropping needle 60 through a third pipe line 70, and a dropping syringe 100 connected to the third pipe line 70 through a fourth pipe line 90; a fifth pipeline 110 is connected between the first communicating valve 30 and the second communicating valve 80.
The liquid path system of the urine analyzer comprises a sample sucking path and a sample dropping path, wherein when the urine analyzer works, a sample sucking needle is moved to a sample sucking position, a first communication valve is controlled to conduct a first pipeline and a second pipeline, then a piston of a liquid sucking injector is controlled to descend, the sample sucking needle sucks a urine sample and transmits the urine sample to the second pipeline, the first communication valve is controlled to disconnect the first pipeline, meanwhile, the first communication valve is opened to connect the fifth pipeline and a second communication valve is opened to connect the third pipeline, the fourth pipeline, the fifth pipeline and the second pipeline are communicated with each other, then the piston of the liquid sucking injector is controlled to ascend, the sample in the second pipeline is transferred to the third pipeline and the fourth pipeline, then, the second communication valve is disconnected, the sample dropping needle is moved to the lower part of a detection test paper, the piston of the sample dropping injector is controlled to ascend, the third pipeline and the fourth pipeline work independently to perform sample dropping, and the sample sucking needle repeatedly sucks the sample in the second pipeline and the sample dropping path, so that the urine analyzer can work and the sample sucking efficiency is improved.
Referring to fig. 1, in a preferred embodiment, the fluid path system further includes a cleaning fluid path, the cleaning fluid path includes a cleaning pool 120, the cleaning pool is connected to the second communication valve 80 through a sixth pipeline 130, the cleaning pool is connected to a cleaning syringe 150 through a seventh pipeline 140, a third communication valve 160 is disposed on the seventh pipeline, and the dropping syringe 150 is connected to the third communication valve 160 through an eighth pipeline 170.
The liquid path system of the invention also has the function of cleaning after absorbing samples, thereby realizing the absorbing samples of different samples, namely in the process of dropping samples on the dropping sample liquid path, the absorbing sample liquid path can be cleaned simultaneously, and the absorbing sample is carried out after cleaning, the specific process is as follows: the second communicating valve is disconnected, the third pipeline and the fourth pipeline run independently, at the moment, the sample sucking needle moves into the cleaning pool, the first communicating valve is controlled to be communicated with the first pipeline and the second pipeline, the third communicating valve is controlled to be communicated with the seventh pipeline, then the piston of the cleaning injector and the piston of the liquid suction injector are controlled to rise simultaneously (the cleaning injector and the liquid suction injector are both connected with an external water pipe, and water is injected into the cleaning injector and the liquid suction injector through the external water pipe before cleaning), and the sample sucking needle is cleaned.
And then controlling the first communicating valve to be disconnected with the first pipeline, simultaneously opening the first communicating valve to be connected with the fifth pipeline and opening the second communicating valve to be connected with the sixth pipeline, continuously lifting the piston of the cleaning injector and the piston of the imbibing injector to clean the fifth pipeline, and after the cleaning is finished, executing the action of sucking the sample into the second pipeline.
Similarly, when a sample sucking path in the liquid path system sucks a sample, the sample dropping path can be cleaned simultaneously, the second communication valve is disconnected from the fifth pipeline during specific operation, the third pipeline and the fourth pipeline run independently, the third communication valve is controlled to conduct the seventh pipeline and open the connection with the eighth pipeline, and then the piston of the cleaning injector is controlled to ascend to clean the sample dropping path.
Referring to fig. 2, fig. 3, fig. 4 and fig. 5, in the technical scheme of the invention, the communication between the pipelines is controlled by reasonably applying the communication valve, so that mutual independence between the sample sucking path and the sample dripping path in the test process can be realized, the sample dripping path can be cleaned simultaneously when the sample sucking path executes the sample sucking process, or the sample dripping path can simultaneously drip samples when the sample sucking path executes the cleaning process, and the processes of sample sucking, liquid separating and cleaning executed by the sample sucking path and the processes of sample dripping and cleaning executed by the sample dripping path can be realized without mutual interference.
Referring to fig. 1, in a preferred embodiment, a fourth communication valve 180 is disposed on the second pipeline, a fifth communication valve 200 is connected to the fourth communication valve 180 through a ninth pipeline 190, the fifth communication valve 200 is connected to the fifth pipeline 110 through a tenth pipeline 210, a sixth communication valve 220 is disposed on the seventh pipeline 140, the cleaning liquid pipeline further includes a cleaning agent tank 230, and the cleaning agent tank 230 is connected to the fifth communication valve 200 and the sixth communication valve 220 through an eleventh pipeline 240 and a twelfth pipeline 250, respectively. In this kind of embodiment, before the pipeline is washd, inject the cleaner in the syringe through opening corresponding communicating valve in the abluent in-process of liquid way, wash the pipeline through the cleaner can make the abluent cleaner of pipeline.
In a preferred embodiment, the first communication valve, the second communication valve, the third communication valve, the fourth communication valve, the fifth communication valve and the sixth communication valve are all three-way solenoid valves.
Referring to fig. 1, in a preferred embodiment, the pipette syringe 50, the drip syringe 100, and the wash syringe 150 are driven by a drive motor 260. The injector and the driving motor in the invention form an injection pump.
Referring to fig. 1, in a preferred embodiment, the cleaning tank 120 is connected to a waste liquid tank 280 through a thirteenth line 270, which is provided with a waste liquid pump 290.
Referring to fig. 1, in a preferred embodiment, a filter 300 is disposed on the first conduit 20.
In addition, the invention also provides a control method of the liquid path system of the urine analyzer, the control method corresponds to the liquid path system and refers to fig. 1, and the control method specifically comprises the following steps:
and (3) a sample sucking process: controlling the sample sucking needle 10 to move to a sample sucking position, controlling the first communicating valve 30 and the fourth communicating valve 180 to communicate the first pipeline 20 and the second pipeline 40, controlling the piston of the imbibing injector 50 to descend for sample sucking, and sucking the sample to the second pipeline 40;
a sample separation process: controlling the first communicating valve 30 to cut off the first pipeline 20, controlling the first communicating valve 30 and the second communicating valve 80 to conduct the second pipeline 40, the fifth pipeline 110 and the third pipeline 70, and controlling the piston of the imbibing injector 50 to ascend to transfer the sample in the second pipeline 40 to the third pipeline 70 and the fourth pipeline 90;
dropping the sample: and controlling the sample dropping needle 60 to move above the detection test paper and controlling the second communication valve 80 to disconnect the fifth pipeline 110, and controlling the piston of the sample dropping injector 100 to ascend so as to drop the samples in the third pipeline 70 and the fourth pipeline 80 onto the detection test paper through the sample dropping needle.
In a preferred embodiment, the control method further includes:
and (3) cleaning a sample sucking liquid path: controlling the first communication valve 30 and the fourth communication valve 180 to communicate the first pipeline 20 and the second pipeline 40, controlling the third communication valve 160 and the fourth communication valve 170 to communicate the seventh pipeline 140, controlling the piston of the pipette syringe 50 and the piston of the wash syringe 150 to ascend, and completing the washing of the pipette paths;
the first communicating valve 30 is controlled to cut off the first pipe line 20, the second communicating valve 80 is controlled to conduct the fifth pipe line 110 and the sixth pipe line 130, the fourth communicating valve 180 and the fifth communicating valve 200 are controlled to conduct the second pipe line 40, the ninth pipe line 190 and the tenth pipe line 210, the piston of the pipette syringe 50 and the piston of the cleaning syringe 150 are controlled to ascend, and the cleaning of the fifth pipe line 110 is completed.
Naturally, the step of injecting the cleaning agent into the cleaning injector and the imbibing injector is included before cleaning, the process of injecting the cleaning agent into the imbibing injector is to control the fourth communicating valve and the fifth communicating pipe valve to conduct the eleventh pipeline, the ninth pipeline and the second pipeline, control the piston of the imbibing injector to move downwards and suck the cleaning agent, and the process of injecting the cleaning agent into the cleaning injector is to control the sixth communicating valve to conduct the twelfth pipeline and the seventh pipeline, control the piston of the cleaning injector to move downwards and suck the cleaning agent.
In a preferred embodiment, the control method further includes:
and (3) cleaning a sample dripping path: the second communicating valve 80 is controlled to conduct the third line 70 and the fifth line 110, the fourth communicating valve 180 and the fifth communicating valve 200 are controlled to conduct the second line 40, the ninth line 190 and the tenth line 210, the third communicating valve 160 and the sixth communicating valve 220 are controlled to conduct the seventh line 140 and the eighth line 170, the piston of the pipette syringe 50 and the piston of the wash syringe 150 are controlled to ascend, and the washing of the dropping sample path is completed.
In summary, the present invention provides a liquid path system of a urine analyzer and a method for implementing the same, wherein the system includes a sample sucking path and a sample dropping path, the sample sucking path includes a sample sucking needle, a first communicating valve connected to the sample sucking needle through a first pipeline, and a liquid sucking injector connected to the first communicating valve through a second pipeline; the sample dropping liquid path comprises a sample dropping needle, a second communicating valve connected with the sample dropping needle through a third pipeline and a dropping injector connected with the third pipeline through a fourth pipeline; and a fifth pipeline is connected between the first communicating valve and the second communicating valve. The liquid path system comprises a sample sucking liquid path and a sample dripping liquid path, can completely separate a sample sucking process and a sample dripping process in a test, and greatly improves the test speed because the sample sucking process and the sample dripping process are parallel.
It is to be understood that the invention is not limited to the examples described above, but that modifications and variations may be effected thereto by those of ordinary skill in the art in light of the foregoing description, and that all such modifications and variations are intended to be within the scope of the invention as defined by the appended claims.

Claims (8)

1. A liquid path system of a urine analyzer is characterized by comprising a sample sucking liquid path and a sample dripping liquid path, wherein the sample sucking liquid path comprises a sample sucking needle, a first communicating valve connected with the sample sucking needle through a first pipeline and a liquid suction injector connected with the first communicating valve through a second pipeline; the sample dropping liquid path comprises a sample dropping needle, a second communicating valve connected with the sample dropping needle through a third pipeline and a dropping injector connected with the third pipeline through a fourth pipeline; a fifth pipeline is connected between the first communicating valve and the second communicating valve; still include the cleaning solution way, the cleaning solution way is including wasing the pond, wash the pond through the sixth pipeline with the second intercommunication valve links to each other, it has the washing syringe to wash the pond through seventh pipe connection, be provided with the third intercommunication valve on the seventh pipeline, the dropping liquid syringe through the eighth pipeline with the third intercommunication valve links to each other, it has the waste liquid groove through the thirteenth pipe connection to wash the pond, be provided with the waste liquid pump on the thirteenth pipe.
2. The fluid path system according to claim 1, wherein a fourth communication valve is arranged on the second pipeline, the fourth communication valve is connected with a fifth communication valve through a ninth pipeline, the fifth communication valve is connected with the fifth pipeline through a tenth pipeline, a sixth communication valve is arranged on the seventh pipeline, the cleaning fluid path further comprises a cleaning agent tank, and the cleaning agent tank is respectively connected with the fifth communication valve and the sixth communication valve through an eleventh pipeline and a twelfth pipeline.
3. The fluid path system of claim 2, wherein the first, second, third, fourth, fifth, and sixth communication valves are three-way solenoid valves.
4. The fluid path system of claim 1, wherein the aspiration syringe, the drip syringe, and the purge syringe are driven by a drive motor.
5. The fluid path system of claim 1, wherein a filter is disposed on the first conduit.
6. A control method of a liquid path system of a urine analyzer is characterized by comprising the following steps:
and (3) a sample sucking process: controlling the sample sucking needle to move to a sample sucking position, controlling the first communicating valve and the fourth communicating valve to communicate the first pipeline and the second pipeline, controlling the piston of the liquid suction injector to descend for sample sucking, and sucking the sample to the second pipeline;
a sample separation process: controlling the first communicating valve to disconnect the first pipeline, controlling the first communicating valve and the second communicating valve to connect the second pipeline, the fifth pipeline and the third pipeline, and controlling the piston of the imbibition injector to ascend to transfer the sample in the second pipeline to the third pipeline and the fourth pipeline;
dropping the sample: and controlling the sample dripping needle to move above the detection test paper and controlling the second communication valve to disconnect the fifth pipeline, and controlling the piston of the sample dripping injector to ascend to drip the samples in the third pipeline and the fourth pipeline onto the detection test paper through the sample dripping needle.
7. The control method according to claim 6, characterized by further comprising:
and (3) cleaning a sample sucking liquid path: controlling the first communicating valve and the fourth communicating valve to communicate the first pipeline and the second pipeline, controlling the third communicating valve and the fourth communicating valve to communicate the seventh pipeline, and controlling the piston of the imbibition syringe and the piston of the cleaning syringe to ascend to complete cleaning of the imbibition liquid channel;
and controlling the first connecting valve to break the first pipeline, controlling the second connecting valve to conduct the fifth pipeline and the sixth pipeline, controlling the fourth connecting valve and the fifth connecting valve to conduct the second pipeline, the ninth pipeline and the tenth pipeline, and controlling the piston of the imbibition syringe and the piston of the cleaning syringe to ascend to complete cleaning of the fifth pipeline.
8. The control method according to claim 6, characterized by further comprising:
and (3) cleaning a sample dripping path: and controlling the second communicating valve to conduct the third pipeline and the fifth pipeline, controlling the fourth communicating valve and the fifth communicating valve to conduct the second pipeline, the ninth pipeline and the tenth pipeline, controlling the third communicating valve and the sixth communicating valve to conduct the seventh pipeline and the eighth pipeline, controlling the piston of the imbibition syringe and the piston of the cleaning syringe to ascend, and completing cleaning of the sample dropping path.
CN201811603521.0A 2018-12-26 2018-12-26 Liquid path system of urine analyzer and control method thereof Active CN109725169B (en)

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EP0513789A2 (en) * 1991-05-16 1992-11-19 Nec Corporation Method and apparatus for detecting and determining components of body fluids
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CN102221627A (en) * 2011-05-24 2011-10-19 长春迪瑞医疗科技股份有限公司 Automatic reagent dropping system of urine analysis meter
CN102305870A (en) * 2011-07-25 2012-01-04 长春迪瑞医疗科技股份有限公司 Two-channel liquid path system of urinary sediment analyzer
CN206096165U (en) * 2016-08-26 2017-04-12 山东宝威生物科技有限公司 Arena analysis appearance four -channel unites test system
CN207007802U (en) * 2017-07-19 2018-02-13 深圳小孚医疗科技有限公司 A kind of liquid-way system for analyzing liquid sample
CN108362865A (en) * 2017-12-29 2018-08-03 迪瑞医疗科技股份有限公司 A kind of method and liquid channel system of test secretion

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0513789A2 (en) * 1991-05-16 1992-11-19 Nec Corporation Method and apparatus for detecting and determining components of body fluids
CN202002928U (en) * 2011-02-17 2011-10-05 杭州龙鑫科技有限公司 Integrated full-automatic urine analysis system integrating dry chemistry and urinary sediment analysis
CN102221627A (en) * 2011-05-24 2011-10-19 长春迪瑞医疗科技股份有限公司 Automatic reagent dropping system of urine analysis meter
CN102305870A (en) * 2011-07-25 2012-01-04 长春迪瑞医疗科技股份有限公司 Two-channel liquid path system of urinary sediment analyzer
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