CN207007802U - A kind of liquid-way system for analyzing liquid sample - Google Patents
A kind of liquid-way system for analyzing liquid sample Download PDFInfo
- Publication number
- CN207007802U CN207007802U CN201720875554.5U CN201720875554U CN207007802U CN 207007802 U CN207007802 U CN 207007802U CN 201720875554 U CN201720875554 U CN 201720875554U CN 207007802 U CN207007802 U CN 207007802U
- Authority
- CN
- China
- Prior art keywords
- liquid
- sample
- solenoid valve
- state
- way solenoid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model provides a kind of liquid-way system for analyzing liquid sample, including the first four way solenoid valve, the second four way solenoid valve, first liquid pump, second liquid pump, and first sample operating unit, the second sample operations unit, first four way solenoid valve connects the first liquid pump and first sample operating unit respectively, second four way solenoid valve connects second liquid pump and the second sample operations unit respectively, and the first four way solenoid valve is connected with the second four way solenoid valve using two pipelines.The utility model can make the partial function of liquid-way system realize two-way parallel processing, improve the running efficiency of system of sample analysis.
Description
Technical field
The present invention relates to fluid specimen sample analysis instrument field, more particularly to the liquid-way system in analytical instrument.
Background technology
Fluid specimen sample analysis is analysis means important in analysis field., it is necessary to do water to water source sample in environmental monitoring
Matter is analyzed, it is necessary to analyze body fluid sample, it is necessary to analyze oil product sample in chemical industry in medical field.
The instrument of liquid sample is analyzed, the instrument of especially continuous quick analysis different liquids sample, can be related to sucking
Sample liquid, sample liquid mix with reaction solution, mixing liquid reacts under catalyst action, sample liquid dyes, sample
The problem of heating of this liquid, the detection of sample liquid constant temperature, sample liquid and detergent line, what different instruments was faced asks
Topic is not quite similar.Traditional mode is serial process, after finishing a step, into next step.But this mode speed
Degree is slower, and efficiency is low.
The content of the invention
To solve the above problems, the present invention provides a kind of sample analysis liquid-way system based on four way solenoid valve, it is intended to carries
Rise the liquid-way system operational efficiency of analytical instrument.
A kind of sample analysis liquid-way system based on four way solenoid valve, including the first four way solenoid valve, the second four-way electromagnetic
Valve, the first liquid pump, second liquid pump, and first sample operating unit, the second sample operations unit, the described 1st is powered
Magnet valve connects first liquid pump and first sample operating unit respectively, and second four way solenoid valve connects described respectively
Two liquid pumps and the second sample operations unit, first pipeline connect the described 1st with second pipeline with parallel form
Three-way electromagnetic valve and second four way solenoid valve;First liquid pump passes through first four way solenoid valve, first pipe
Road, second four way solenoid valve connect the second liquid pump;The first sample operating unit passes through first four-way
Magnetic valve, second pipeline, second four way solenoid valve connect the second sample operations unit.
First four way solenoid valve is two position four-way solenoid valves, including interface A, interface B, interface C, interface D, what it was not powered on
State 0 for interface A is connected with interface B, interface C is connected with interface D, the state 1 of energization be interface A be connected with interface C, interface B
It is connected with interface D.
Second four way solenoid valve is two position four-way solenoid valves, including interface A, interface B, interface C, interface D, what it was not powered on
State 0 for interface A is connected with interface B, interface C is connected with interface D, the state 1 of energization be interface A be connected with interface C, interface B
It is connected with interface D.
First four way solenoid valve replaces switching unpowered and powered state with second four way solenoid valve, and combination forms four
Kind liquid-way system state, it is respectively { 0,0 }, { 1,0 }, { 0,1 }, { 1,1 }.
Preferably, state { 1,0 } is alternately present with state { 0,1 }.
Preferably, liquid-way system of the invention also includes the 3rd liquid pump, the 3rd liquid pump and the second sample operations list
Member is connected.
Preferably, state { 1,0 }, state { 0,0 }, state { 0,1 }, state { 1,1 } sequentially occur.
Preferably, the internal capacity of the internal capacity of the first pipeline and the second pipeline is equal.
Beneficial effects of the present invention:The function of liquid-way system is realized two-way parallel processing, improve the operation of analytical instrument
Efficiency.
Brief description of the drawings
Accompanying drawing 1 is the sample analysis liquid-way system structural representation based on four way solenoid valve of the invention.
Accompanying drawing 2 is sample analysis liquid-way system state { 1,0 } schematic diagram based on four way solenoid valve of the invention.
Accompanying drawing 3 is sample analysis liquid-way system state { 0,1 } schematic diagram based on four way solenoid valve of the invention.
Accompanying drawing 4 is sample analysis liquid-way system state { 1,1 } schematic diagram based on four way solenoid valve of the invention.
Accompanying drawing 5 is the first embodiment schematic diagram of the sample analysis liquid-way system based on four way solenoid valve of the present invention.
Accompanying drawing 6 is the second embodiment schematic diagram of the sample analysis liquid-way system based on four way solenoid valve of the present invention.
Accompanying drawing 7 is the 3rd embodiment schematic diagram of the sample analysis liquid-way system based on four way solenoid valve of the present invention.
Accompanying drawing 8 adds the 3rd pump configuration schematic diagram for the sample analysis liquid-way system based on four way solenoid valve of the present invention.
Accompanying drawing 9 is the pump configuration state of addition the 3rd of the sample analysis liquid-way system based on four way solenoid valve of the present invention
{ 1,0 } schematic diagram.
Accompanying drawing 10 is the pump configuration state of addition the 3rd of the sample analysis liquid-way system based on four way solenoid valve of the present invention
{ 0,1 } schematic diagram.
Accompanying drawing 11 is the pump configuration state of addition the 3rd of the sample analysis liquid-way system based on four way solenoid valve of the present invention
{ 1,1 } schematic diagram.
Accompanying drawing 12 is the fourth embodiment schematic diagram of the sample analysis liquid-way system based on four way solenoid valve of the present invention.
Accompanying drawing 13 is the 5th embodiment schematic diagram of the sample analysis liquid-way system based on four way solenoid valve of the present invention.
Accompanying drawing 14 is the sixth embodiment schematic diagram of the sample analysis liquid-way system based on four way solenoid valve of the present invention.
Accompanying drawing 15 is the 7th embodiment schematic diagram of the sample analysis liquid-way system based on four way solenoid valve of the present invention.
Embodiment
The present invention is described in further detail below in conjunction with the accompanying drawings, to make those skilled in the art with reference to specification text
Word can be implemented according to this.
Referring to the drawings 1, the sample analysis liquid-way system of the invention based on four way solenoid valve, including the first four way solenoid valve
101st, the second four way solenoid valve 102, the first liquid pump 201, second liquid pump 202, and first sample operating unit 301,
Two sample operations units 302, and the first pipeline 401, the second pipeline 402.First four way solenoid valve 101 connects the first liquid respectively
Pump 201 and first sample operating unit 301, the second four way solenoid valve 102 connect the sample of second liquid pump 202 and second behaviour respectively
Make unit 302, the first four way solenoid valve 101 passes through the first pipeline 401 and the phase of the second pipeline 402 with the second four way solenoid valve 102
Connection.
First four way solenoid valve 101 is under the state 0 being not powered on, and its interface is connected for interface A with interface B, interface C is with connecing
Mouth D is connected;Under the state 1 of energization, its interface is interface A is connected with interface C, interface B is connected with interface D;Two or four is powered
Magnet valve 102 is under the state 0 being not powered on, and its interface is interface A is connected with interface B, interface C is connected with interface D;In the shape of energization
Under state 1, its interface is interface A is connected with interface C, interface B is connected with interface D.First pipeline 401 connects the first four way solenoid valve
The A end interfaces of 101 B end interfaces and the second four way solenoid valve 102;Second pipeline 402 connects the C of the first four way solenoid valve 101
The D end interfaces of end interface and the second four way solenoid valve 102.First liquid pump 201 connects the A terminations of the first four way solenoid valve 101
Mouthful;First sample operating unit 301 connects the D end interfaces of the first four way solenoid valve 101;The connection of second liquid pump 202 the two or four
The B end interfaces of three-way electromagnetic valve 102;Second sample operations unit 302 connects the C-terminal interface of the second four way solenoid valve 102.
There is following four state in the liquid-way system of the present invention:
(1)Referring to the drawings 1, when the first four way solenoid valve 101 and the second four way solenoid valve 102 are in the state 0 being not powered on
When lower, i.e., state { 0,0 } when, the first liquid pump 201 is communicated to second liquid pump 202 by the first pipeline 401;First sample is grasped
Make unit 301 and second sample operations unit 302 is communicated to by the second pipeline 402.Under this state, none of liquid
Pump is attached to any one sample operations unit, and liquid-way system is without practical operation meaning.
(2)Referring to the drawings 2, when the first four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in
During the state 0 being not powered on, i.e., state { 1,0 } when, the first liquid pump 201 is communicated to the second sample operations by the second pipeline 402
Unit 302;Second liquid pump 202 is communicated to first sample operating unit 301 by the first pipeline 401.Under this state, first
Liquid pump 201 can carry out transport operation to the liquid in the second pipeline 402 and the second sample operations unit 302;At the same time
Second liquid pump 202 can carry out transport operation to the liquid in the first pipeline 401 and first sample operating unit 301.
(3)Referring to the drawings 3, when the first four way solenoid valve 101 is in unpowered state 0, and at the second four way solenoid valve 102
In the state 1 of energization, i.e., state { 0,1 } when, the first liquid pump 201 is communicated to the second sample operations by the first pipeline 401
Unit 302;Second liquid pump 202 is communicated to first sample operating unit 301 by the second pipeline 402.Under this state, first
Liquid pump 201 can carry out transport operation to the liquid in the first pipeline 401 and the second sample operations unit 302;At the same time
Second liquid pump 202 can carry out transport operation to the liquid in the second pipeline 402 and first sample operating unit 301.
(4)Referring to the drawings 4, when the first four way solenoid valve 101 and the second four way solenoid valve 102 are under the state 1 of energization
When, i.e., state { 1,1 } when, the first liquid pump 201 is communicated to second liquid pump 202 by the second pipeline 402;First sample operates
Unit 301 is communicated to the second sample operations unit 302 by the first pipeline 401.Under this state, none of liquid pump
Any one sample operations unit is attached, liquid-way system is without practical operation meaning.
In actual use, referring to the drawings shown in 5, the first embodiment of the present invention can be using sampling probe 301a as first
Sample operations unit 301, also there is detection using detection cell 302a as the second sample operations unit 302, detection cell 302a sides
Device 302b.Liquid in first liquid pump 201 is buffer solution, and the liquid in second liquid pump 202 is identical buffer solution.Liquid
Road system can have following occupation mode:
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 0 being not powered on,
I.e. state { 1,0 } when, now the first liquid pump 201 is communicated to by the second pipeline 402 is used as the second sample operations unit 302
Detection cell 302a;Second liquid pump 202 is communicated to the sampling spy for being used as first sample operating unit 301 by the first pipeline 401
Pin 301a.Under this state, the first liquid pump 201 can be will be present in the second pipeline 402 by discharging the action of liquid
Liquid is pushed in the detection cell 302a as the second sample operations unit 302, it is detected by detection means 302b;With this
Second liquid pump 202 can be by drawing the action of liquid by the sample liquid of outside from being used as first sample operating unit simultaneously
It is drawn at 301 sampling probe 301a in the first pipeline 401, to prepare to detect in next step.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state 1 of energization,
I.e. state { 0,1 } when, now the first liquid pump 201 is communicated to by the first pipeline 401 is used as the second sample operations unit 302
Detection cell 302a;Second liquid pump 202 is communicated to the sampling spy for being used as first sample operating unit 301 by the second pipeline 402
Pin 301a.Under this state, the first liquid pump 201 can be will be present in the first pipeline 401 by discharging the action of liquid
Liquid is pushed in the detection cell 302a as the second sample operations unit 302, it is detected by detection means 302b;With this
Second liquid pump 202 can be by drawing the action of liquid by the sample liquid of outside from being used as first sample operating unit simultaneously
It is drawn at 301 sampling probe in the second pipeline 402, to prepare to detect in next step.
First four way solenoid valve 101 is engaged switching state with the second four way solenoid valve 102, makes state { 1,0 } and state
{ 0,1 } alternately occurs, and sample and detection sample are acquired while can replacing the first pipeline 401 and the second pipeline 402
This action, actuation time is saved, improve liquid-way system operational efficiency.To ensure the uniformity of testing result, the first pipeline 401
Internal volume and the internal volume of the second pipeline 402 should be equal.Preferably, the first pipeline 401 and the second pipeline 402 are from identical
Material, same size caliber, the pipe of equal length.
In actual use, referring to the drawings shown in 6, the second embodiment of the present invention can be using mixing pit 301b as the first sample
This operating unit 301, dyeing storehouse 302c will be heated as the second sample operations unit 302, heating dyeing storehouse 302c, which also has, to be added
Hot device 302d and dyestuff 302e.Liquid in first liquid pump 201 is buffer solution, and the liquid in second liquid pump 202 is identical
Buffer solution.Liquid-way system can have following occupation mode:
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 0 being not powered on,
I.e. state { 1,0 } when, now the first liquid pump 201 is communicated to by the second pipeline 402 is used as the second sample operations unit 302
Heating dyeing storehouse 302c;Second liquid pump 202 is communicated to by the first pipeline 401 is used as the mixed of first sample operating unit 301
Close pond 301b.Under this state, the first liquid pump 201 can be will be present in the second pipeline 402 by discharging the action of liquid
Liquid be pushed to as the second sample operations unit 302 heating dyeing storehouse 302c in, it is added by heater 302d
Heat is simultaneously dyed by dyestuff 302e;At the same time second liquid pump 202 can be by drawing the action of liquid by mixed sample
This liquid is drawn at the mixing pit 301b as first sample operating unit 301 in first pipeline 401, to prepare in next step
Heating dyeing.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state 1 of energization,
I.e. state { 0,1 } when, now the first liquid pump 201 is communicated to by the first pipeline 401 is used as the second sample operations unit 302
Heating dyeing storehouse 302c;Second liquid pump 202 is communicated to by the second pipeline 402 is used as the mixed of first sample operating unit 301
Close pond 301b.Under this state, the first liquid pump 201 can be will be present in the first pipeline 401 by discharging the action of liquid
Liquid be pushed to as the second sample operations unit 302 heating dyeing storehouse 302c in, it is added by heater 302d
Heat is simultaneously dyed by dyestuff 302e;At the same time second liquid pump 202 can be by drawing the action of liquid by mixed sample
This liquid is drawn at the mixing pit 301b as first sample operating unit 301 in second pipeline 402, to prepare in next step
Heating dyeing.
First four way solenoid valve 101 is engaged switching state with the second four way solenoid valve 102, makes state { 1,0 } and state
{ 0,1 } alternately occurs, and mixing liquid is collected while can replacing the first pipeline 401 and the second pipeline 402 and is added
The action of heat tinting color, actuation time is saved, improve liquid-way system operational efficiency.To ensure liquid mixing and heating Color
Uniformity, the internal volume of the internal volume of the first pipeline 401 and the second pipeline 402 should be equal.Preferably, the first pipeline 401
Phase same material, same size caliber, the pipe of equal length are selected with the second pipeline 402.
In actual use, referring to the drawings shown in 7, the third embodiment of the present invention can be using mixing pit 301b as the first sample
This operating unit 301, reaction is built-in with using catalytic reaction pond 302f as the second sample operations unit 302, reaction tank 302f
Catalyst 302g, side have constant temperature heating device 302i, its outside detection means 302h with detection catalytic reaction state.
Liquid in first liquid pump 201 is buffer solution, and the liquid in second liquid pump 202 is identical buffer solution.Liquid-way system can
To there is following occupation mode:
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 0 being not powered on,
I.e. state { 1,0 } when, now the first liquid pump 201 is communicated to by the second pipeline 402 is used as the second sample operations unit 302
Catalytic reaction pond 302f;Second liquid pump 202 is communicated to by the first pipeline 401 is used as the mixed of first sample operating unit 301
Close pond 301b.Under this state, the first liquid pump 201 can be will be present in the second pipeline 402 by discharging the action of liquid
Completed mixing sample liquid be pushed in the catalytic reaction pond 302f as the second sample operations unit 302, make its
Reacted after contacting catalyst 302g under suitable temperature, its response situation is detected by detection means 302h;At the same time
Two liquid pumps 202 can be by drawing the action of liquid by mixed sample liquid from being used as first sample operating unit 301
Mixing pit 301b at be drawn in the first pipeline 401, to prepare to react.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state 1 of energization,
I.e. state { 0,1 } when, now the first liquid pump 201 is communicated to by the first pipeline 401 is used as the second sample operations unit 302
Catalytic reaction pond 302f;Second liquid pump 202 is communicated to by the second pipeline 402 is used as the mixed of first sample operating unit 301
Close pond 301b.Under this state, the first liquid pump 201 can be will be present in the first pipeline 401 by discharging the action of liquid
Completed mixing sample liquid be pushed in the catalytic reaction pond 302f as the second sample operations unit 302, make its
Reacted after contacting catalyst 302g under suitable temperature, its response situation is detected by detection means 302h;At the same time
Two liquid pumps 202 can be by drawing the action of liquid by mixed sample liquid from being used as first sample operating unit 301
Mixing pit 301b at be drawn in the second pipeline 402, to prepare to react.
First four way solenoid valve 101 is engaged switching state with the second four way solenoid valve 102, makes state { 1,0 } and state
{ 0,1 } alternately occurs, be collected while can replacing the first pipeline 401 and the second pipeline 402 mixing liquid and
The action of catalytic reaction, actuation time is saved, improve liquid-way system operational efficiency.The length of first pipeline 401 and the second pipeline 402
Degree and diameter should correspondent equal so that its internal volume is equal, so as to ensure the uniformity of sample liquid amount, so that it is guaranteed that reaction
The uniformity of testing result.
In actual use, the sample analysis liquid-way system of the invention based on four way solenoid valve, in addition to it is directly connected to
3rd liquid pump 203 of two sample operations units 302.3rd liquid pump 203 can be used for the pump of the second sample operations unit 302
Enter liquid, such as buffer solution, cleaning fluid, reaction solution.
Referring to the drawings 8, the sample analysis liquid-way system of the invention based on four way solenoid valve, in addition to be directly connected to second
3rd liquid pump 203 of sample operations unit 302, the 3rd liquid pump 203 have two kinds of effects:One is with the first liquid pump
201 coordinate, while to the pumping liquid of the second sample operations unit 302, make to come from the first pipeline 401 or the second pipeline 402
Liquid mixes or reacted in the second sample operations unit 302 with the liquid from the 3rd liquid pump 203;The second is can be with
Power is directly provided liquid in the second sample operations unit 302 is pushed to first by the first pipeline 401 or the second pipeline 402
Sample operations unit 301.
There is following four state after comprising the 3rd liquid pump 203 in the liquid-way system of the present invention:
(1)Referring to the drawings 8, when the first four way solenoid valve 101 and the second four way solenoid valve 102 are in the state 0 being not powered on
When, i.e., state { 0,0 } when, the first liquid pump 201 is communicated to second liquid pump 202 by the first pipeline 401;First sample operates
Unit 301 is communicated to the second sample operations unit 302 and the 3rd liquid pump 203 by the second pipeline 402.Under this state, the
Three liquid pumps 203 can be to the liquid in first sample operating unit 301, the second pipeline 402 and the second sample operations unit 302
Carry out transport operation.
(2)Referring to the drawings 9, when the first four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in
During the state 0 being not powered on, i.e., state { 1,0 } when, the first liquid pump 201 is communicated to the second sample operations by the second pipeline 402
Unit 302;Second liquid pump 202 is communicated to first sample operating unit 301 by the first pipeline 401.Under this state, first
Liquid pump 201 can carry out transport operation, while the 3rd to the liquid in the second pipeline 402 and the second sample operations unit 302
Liquid pump carries out transport operation to the liquid in the second sample operations unit 302;At the same time second liquid pump 202 can be to
Liquid in one pipeline 401 and first sample operating unit 301 carries out transport operation.
(3)Referring to the drawings 10, when the first four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102
When being in the state 1 of energization, i.e., state { 0,1 } when, the first liquid pump 201 by the first pipeline 401 be communicated to the second sample grasp
Make unit 302;Second liquid pump 202 is communicated to first sample operating unit 301 by the second pipeline 402.Under this state, the
One liquid pump 201 can carry out transport operation, while the to the liquid in the first pipeline 401 and the second sample operations unit 302
Three liquid pumps carry out transport operation to the liquid in the second sample operations unit 302;At the same time second liquid pump 202 can be right
Liquid in second pipeline 402 and first sample operating unit 301 carries out transport operation.
(4)Referring to the drawings 11, when the first four way solenoid valve 101 and the second four way solenoid valve 102 are under the state 1 of energization
When, i.e., state { 1,1 } when, the first liquid pump 201 is communicated to second liquid pump 202 by the second pipeline 402;First sample operates
Unit 301 is communicated to the second sample operations unit 302 and the 3rd liquid pump 203 by the first pipeline 401.Under this state, the
Three liquid pumps 203 can be to the liquid in first sample operating unit 301, the first pipeline 401 and the second sample operations unit 302
Carry out transport operation.
In actual use, referring to the drawings shown in 12, the fourth embodiment of the present invention can regard sampling probe 301a as the
One sample operating unit 301, also there is inspection using detection cell 302a as the second sample operations unit 302, detection cell 302a sides
Survey device 302b.Liquid in first liquid pump 201 is buffer solution, and the liquid in second liquid pump 202 is identical buffer solution,
And the 3rd liquid in liquid pump 203 is also identical buffer solution.Liquid-way system can have following occupation mode:
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 0 being not powered on,
I.e. state { 1,0 } when, now the first liquid pump 201 is communicated to by the second pipeline 402 is used as the second sample operations unit 302
Detection cell 302a, the detection cell 302a as the second sample operations unit 302 are also connected with the 3rd liquid pump 203;Second liquid
Body pump 202 is communicated to the sampling probe 301a for being used as first sample operating unit 301 by the first pipeline 401.Under this state,
The liquid that first liquid pump 201 can be will be present in the second pipeline 402 by discharging the action of liquid, which is pushed to, is used as second
In the detection cell 302a of sample operations unit 302, the 3rd 203 action simultaneously by discharging liquid of liquid pump pushes buffer solution
Into the detection cell 302a as the second sample operations unit 302, the sample liquid for making to be stored in the second pipeline 402 is buffering
Detected under pendular ring border by detection means 302b;At the same time second liquid pump 202 can be by drawing the action of liquid by outside
The sample liquid in portion is drawn at the sampling probe 301a as first sample operating unit 301 in first pipeline 401, with standard
It is standby to detect in next step.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state being not powered on
0, i.e., state { 0,0 } when, now the first liquid pump 201 is communicated to second liquid pump 202 by the first pipeline 401;As first
The sampling probe 301a of sample operations unit 301 is communicated to the inspection for being used as the second sample operations unit 302 by the second pipeline 402
Survey pond 302a and the 3rd liquid pump 203.Under this state, the 3rd liquid pump 203 by discharge the action of liquid by buffer solution according to
Secondary detection cell 302a and the second pipeline 402 by as the second sample operations unit 302, and it is single from being operated as first sample
The sampling probe 301a discharges of member 301, so as to complete to the detection cell 302a as the second sample operations unit 302, the second pipe
Road 402 and the cleaning of sampling probe 301a as first sample operating unit 301.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state 1 of energization,
I.e. state { 0,1 } when, now the first liquid pump 201 is communicated to by the first pipeline 401 is used as the second sample operations unit 302
Detection cell 302a, the detection cell 302a as the second sample operations unit 302 are also connected with the 3rd liquid pump 203;Second liquid
Body pump 202 is communicated to the sampling probe 301a for being used as first sample operating unit 301 by the second pipeline 402.Under this state,
The liquid that first liquid pump 201 can be will be present in the first pipeline 401 by discharging the action of liquid, which is pushed to, is used as second
In the detection cell 302a of sample operations unit 302, the 3rd 203 action simultaneously by discharging liquid of liquid pump pushes buffer solution
Into the detection cell 302a as the second sample operations unit 302, the sample liquid for making to be stored in the first pipeline 401 is buffering
Detected under pendular ring border by detection means 302b;At the same time second liquid pump 202 can be by drawing the action of liquid by outside
The sample liquid in portion is drawn at the sampling probe 301a as first sample operating unit 301 in second pipeline 402, with standard
Standby postorder detects.
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 1 of energization, i.e.,
During state { 1,1 }, now the first liquid pump 201 is communicated to second liquid pump 202 by the second pipeline 402;As first sample
The sampling probe 301a of operating unit 301 is communicated to the second sample operations unit 302 and the 3rd liquid pump by the first pipeline 401
203.Under this state, action of the 3rd liquid pump 203 by discharging liquid grasps buffer solution by being used as the second sample successively
Make the detection cell 302a and the first pipeline 401 of unit 302, and from the sampling probe 301a as first sample operating unit 301
Discharge, so as to complete to the detection cell 302a as the second sample operations unit 302, the first pipeline 401 and as first sample
The sampling probe 301a of operating unit 301 cleaning.
First four way solenoid valve 101 is engaged switching state with the second four way solenoid valve 102, is sequentially combined into as described above four
Kind state, i.e. state { 1,0 }, { 0,0 }, { 0,1 }, { 1,1 }, while the first pipeline 401 and the second pipeline 402 alternating can be made
It is acquired sample and detects the action of sample, and interspersed cleaning action, actuation time is saved, improves liquid-way system operation effect
Rate.For the uniformity of guarantee testing result, the internal volume of the internal volume of the first pipeline 401 and the second pipeline 402 should be equal.It is excellent
Choosing, the first pipeline 401 and the second pipeline 402 select phase same material, same size caliber, the pipe of equal length.
In actual use, referring to the drawings shown in 13, the fifth embodiment of the present invention can be by the diluting tank with leakage fluid dram
301c is as first sample operating unit 301, using catalytic reaction pond 302f as the second sample operations unit 302, the reaction tank
302f is built-in with catalysts 302g, and side has constant temperature heating device 302i, and it is outside with detection catalytic reaction state
Detection means 302h.Liquid in first liquid pump 201 is reactant solution, and the liquid in second liquid pump 202 is buffering
Liquid, and the liquid in the 3rd liquid pump 203 is cleaning fluid.Liquid-way system can have following occupation mode:
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 0 being not powered on,
I.e. state { 1,0 } when, now the first liquid pump 201 is communicated to by the second pipeline 402 is used as the second sample operations unit 302
Catalytic reaction pond 302f;Second liquid pump 202 is communicated to the band for being used as first sample operating unit 301 by the first pipeline 401
There is the diluting tank 301c of leakage fluid dram.Under this state, the first liquid pump 201 can will be present in by discharging the action of liquid
The reactant solution in sample liquid and the first liquid pump 201 in two pipelines 402 is pushed to as the second sample operations list
In the catalytic reaction pond 302f of member 302, the sample liquid for making to be stored in the second pipeline 402 is with reactant solution in suitable temperature
Reacted after lower contact catalyst 302g, its response situation is detected by detection means 302h;At the same time second liquid pump
202 can by draw the action of liquid by the sample liquid after dilution from be used as first sample operating unit 301 with row
It is drawn at the diluting tank 301c of liquid mouth in the first pipeline 401, to prepare postorder reaction.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state being not powered on
0, i.e., state { 0,0 } when, now the first liquid pump 201 is communicated to second liquid pump 202 by the first pipeline 401;As first
The diluting tank 301c with leakage fluid dram of sample operations unit 301 is communicated to by the second pipeline 402 is used as the second sample operations
The catalytic reaction pond 302f and the 3rd liquid pump 203 of unit 302.Under this state, the 3rd liquid pump 203 is by discharging liquid
Action makes cleaning fluid flow successively through catalytic reaction pond 302f, the second pipeline 402 and conduct as the second sample operations unit 302
The diluting tank 301c with leakage fluid dram of first sample operating unit 301, make leakage fluid dram discharge of the waste liquid through diluting tank 301c, from
And complete to being operated as the catalytic reaction pond 302f of the second sample operations unit 302, the second pipeline 402 and as first sample
The diluting tank 301c with leakage fluid dram of unit 301 cleaning.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state 1 of energization,
I.e. state { 0,1 } when, now the first liquid pump 201 is communicated to by the first pipeline 401 is used as the second sample operations unit 302
Catalytic reaction pond 302f;Second liquid pump 202 is communicated to the band for being used as first sample operating unit 301 by the second pipeline 402
There is the diluting tank 301c of leakage fluid dram.Under this state, the first liquid pump 201 can will be present in by discharging the action of liquid
The reactant solution in sample liquid and the first liquid pump 201 in one pipeline 401 is pushed to as the second sample operations list
In the catalytic reaction pond 302f of member 302, the sample liquid for making to be stored in the first pipeline 401 is with reactant solution in suitable temperature
Reacted after lower contact catalyst 302g, its response situation is detected by detection means 302h;At the same time second liquid pump
202 can by draw the action of liquid by the sample liquid after dilution from be used as first sample operating unit 301 with row
It is drawn at the diluting tank 301c of liquid mouth in the second pipeline 402, to prepare postorder reaction.
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 1 of energization, i.e.,
During state { 1,1 }, now the first liquid pump 201 is communicated to second liquid pump 202 by the second pipeline 402;As first sample
The diluting tank 301c with leakage fluid dram of operating unit 301 is communicated to by the first pipeline 401 is used as the second sample operations unit
302 catalytic reaction pond 302f and the 3rd liquid pump 203.Under this state, the 3rd liquid pump 203 is by discharging the action of liquid
Cleaning fluid liquid is set to flow successively through the catalytic reaction pond 302f as the second sample operations unit 302, the first pipeline 401 and as
The diluting tank 301c with leakage fluid dram of one sample operating unit 301, make leakage fluid dram discharge of the waste liquid through diluting tank 301c, so as to
Complete to as the catalytic reaction pond 302f of the second sample operations unit 302, the first pipeline 401 and single as first sample operation
The diluting tank 301c with leakage fluid dram of member 301 cleaning.
First four way solenoid valve 101 is engaged switching state with the second four way solenoid valve 102, is sequentially combined into as described above four
Kind state, i.e. state { 1,0 }, { 0,0 }, { 0,1 }, { 1,1 }, while the first pipeline 401 and the second pipeline 402 alternating can be made
The action of diluted sample liquid and catalytic reaction, and interspersed cleaning action are collected, actuation time is saved, improves liquid-way system
Operational efficiency.For the uniformity of guarantee reaction result, the internal volume of the internal volume of the first pipeline 401 and the second pipeline 402 should
It is equal.Preferably, the first pipeline 401 and the second pipeline 402 select phase same material, same size caliber, the pipe of equal length.
In actual use, referring to the drawings shown in 14, the sixth embodiment of the present invention can regard sampling probe 301a as the
One sample operating unit 301, using reaction tank 302m as the second sample operations unit 302.Liquid in first liquid pump 201 is
Buffer solution, the liquid in second liquid pump 202 is buffer solution, and the liquid in the 3rd liquid pump 203 is reaction reagent.Fluid path system
System can have following occupation mode:
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 0 being not powered on,
I.e. state { 1,0 } when, now the first liquid pump 201 is communicated to by the second pipeline 402 is used as the second sample operations unit 302
Reaction tank 302m, the reaction tank 302m as the second sample operations unit 302 are also connected with the 3rd liquid pump 203;Second liquid
Body pump 202 is communicated to the sampling probe 301a for being used as first sample operating unit 301 by the first pipeline 401.Under this state,
The sample liquid that first liquid pump 201 can be will be present in the second pipeline 402 by discharging the action of liquid, which is pushed to, is used as
In the reaction tank 302m of second sample operations unit 302, action of the 3rd liquid pump 203 simultaneously by discharging liquid, which will react, to be tried
Agent is pushed in the reaction tank 302m as the second sample operations unit 302, makes the sample liquid being stored in the second pipeline 402
Reacted with reaction reagent, after reaction terminates, the first liquid pump 201 can continue to release buffer solution, using to being used as the
The reaction tank 302m of two sample operations units 302 is cleaned;During reaction is carried out herein, second liquid pump 202 can be with
The action of discharge liquid is first passed through using the first pipeline 401 and as being filled in the sampling probe 301a of first sample operating unit 301
Full buffer solution, to prepare as sample introduction, the then action again by drawing liquid operates sample liquid from first sample is used as
It is drawn at the sampling probe 301a of unit 301 in first pipeline 401, to prepare postorder reaction.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state 1 of energization,
I.e. state { 0,1 } when, now the first liquid pump 201 is communicated to by the first pipeline 401 is used as the second sample operations unit 302
Reaction tank 302m, the reaction tank 302m as the second sample operations unit 302 are also connected with the 3rd liquid pump 203;Second liquid
Body pump 202 is communicated to the sampling probe 301a for being used as first sample operating unit 301 by the second pipeline 402.Under this state,
The sample liquid that first liquid pump 201 can be will be present in the first pipeline 401 by discharging the action of liquid, which is pushed to, is used as
In the reaction tank 302m of second sample operations unit 302, action of the 3rd liquid pump 203 simultaneously by discharging liquid, which will react, to be tried
Agent is pushed in the reaction tank 302m as the second sample operations unit 302, makes the sample liquid being stored in the first pipeline 401
Reacted with reaction reagent, after reaction terminates, the first liquid pump 201 can continue to release buffer solution, using to being used as the
The reaction tank 302m of two sample operations units 302 is cleaned;During reaction is carried out herein, second liquid pump 202 can be with
By first passing through the action of discharge liquid by the second pipeline 402 and being used as the sampling probe 301a of first sample operating unit 301
It is interior to be full of buffer solution, to prepare as sample introduction, then again by drawing the action of liquid by sample liquid from being used as first sample
It is drawn at the sampling probe 301a of operating unit 301 in second pipeline 402, to prepare postorder reaction.
First four way solenoid valve 101 is engaged switching state with the second four way solenoid valve 102, is sequentially combined into as described above two
Kind state, i.e. state { 1,0 }, { 0,1 }, absorption sample is carried out while can replacing the first pipeline 401 and the second pipeline 402
With the action of reaction, and cleaning action is contained, save actuation time, improve liquid-way system operational efficiency.To ensure reaction knot
The internal volume of the uniformity of fruit, the internal volume of the first pipeline 401 and the second pipeline 402 should be equal.Preferably, the first pipeline
401 and second pipeline 402 select phase same material, same size caliber, the pipe of equal length.
In actual use, referring to the drawings shown in 15, the seventh embodiment of the present invention can regard sampling probe 301a as the
One sample operating unit 301, using counting chamber 302j as the second sample operations unit 302, counting chamber 302j is interior to have aperture, should
Counting chamber 302j is divided into former and later two cavitys by aperture, and two inside cavities are respectively provided with an electrode 302k.First liquid pump
Liquid in 201 is buffer solution, and the liquid in second liquid pump 202 is identical buffer solution, and the liquid in the 3rd liquid pump 203
Body is cleaning fluid.Liquid-way system can have following occupation mode:
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 0 being not powered on,
I.e. state { 1,0 } when, now the first liquid pump 201 is communicated to by the second pipeline 402 is used as the second sample operations unit 302
Counting chamber 302j;Second liquid pump 202 is communicated to the sampling spy for being used as first sample operating unit 301 by the first pipeline 401
Pin 301a.Under this state, the first liquid pump 201 can be will be present in the second pipeline 402 by discharging the action of liquid
Sample liquid with particle is pushed in the counting chamber 302j as the second sample operations unit 302, makes to be stored in the second pipe
The sample liquid with particle in road 402 flows through the aperture in counting chamber 302j, and contained particle passes through in sample liquid
Change the resistance of aperture during aperture, detected by electrode 302k;At the same time second liquid pump 202 can be by drawing liquid
Sample liquid with particle is drawn to the first pipe by action at the sampling probe 301a as first sample operating unit 301
In road 401, to prepare postorder counting.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state being not powered on
0, i.e., state { 0,0 } when, now the first liquid pump 201 is communicated to second liquid pump 202 by the first pipeline 401;As first
The sampling probe 301a of sample operations unit 301 is communicated to the meter for being used as the second sample operations unit 302 by the second pipeline 402
Number pond 302j and the 3rd liquid pump 203.Under this state, action of the 3rd liquid pump 203 by discharging liquid make cleaning fluid according to
It is secondary to flow through the counting chamber 302j as the second sample operations unit 302, the second pipeline 402 and be used as first sample operating unit
301 sampling probe 301a, so as to complete to the counting chamber 302j as the second sample operations unit 302, the and of the second pipeline 402
Cleaning as the sampling probe 301a of first sample operating unit 301.
First four way solenoid valve 101 is in unpowered state 0, and the second four way solenoid valve 102 is in the state 1 of energization,
I.e. state { 0,1 } when, now the first liquid pump 201 is communicated to by the first pipeline 401 is used as the second sample operations unit 302
Counting chamber 302j;Second liquid pump 202 is communicated to the sampling spy for being used as first sample operating unit 301 by the second pipeline 402
Pin 301a.Under this state, the first liquid pump 201 can be will be present in the first pipeline 401 by discharging the action of liquid
Sample liquid with particle is pushed in the counting chamber 302j as the second sample operations unit 302, makes to be stored in the first pipe
The sample liquid with particle in road 401 flows through the aperture in counting chamber 302j, and contained particle passes through in sample liquid
Change the resistance of aperture during aperture, detected by electrode 302k;At the same time second liquid pump 202 can be by drawing liquid
Sample liquid with particle is drawn to the second pipe by action at the sampling probe 301a as first sample operating unit 301
In road 402, to prepare postorder counting.
First four way solenoid valve 101 is in "on" position 1, and the second four way solenoid valve 102 is in the state 1 of energization, i.e.,
During state { 1,1 }, now the first liquid pump 201 is communicated to second liquid pump 202 by the second pipeline 402;As first sample
The sampling probe 301a of operating unit 301 is communicated to the counting chamber for being used as the second sample operations unit 302 by the first pipeline 401
302j and the 3rd liquid pump 203.Under this state, action of the 3rd liquid pump 203 by discharging liquid makes cleaning fluid liquid successively
Flow through the counting chamber 302j as the second sample operations unit 302, the first pipeline 401 and as first sample operating unit 301
Sampling probe 301a, so as to complete to the counting chamber 302j as the second sample operations unit 302, the first pipeline 401 and make
For the sampling probe 301a of first sample operating unit 301 cleaning.
First four way solenoid valve 101 is engaged switching state with the second four way solenoid valve 102, is sequentially combined into as described above four
Kind state, i.e. state { 1,0 }, { 0,0 }, { 0,1 }, { 1,1 }, while the first pipeline 401 and the second pipeline 402 alternating can be made
The action of sample liquid and particle counting with particle, and interspersed cleaning action are collected, actuation time is saved, improves liquid
Road running efficiency of system.To ensure the content of the uniformity of reaction result, the internal volume of the first pipeline 401 and the second pipeline 402
Product should be equal.Preferably, the first pipeline 401 and the second pipeline 402 select phase same material, same size caliber, equal length
Pipe.
Claims (8)
1. a kind of liquid-way system for analyzing liquid sample, including the first four way solenoid valve, the second four way solenoid valve, the first liquid
Pump, second liquid pump, and first sample operating unit, the second sample operations unit, first four way solenoid valve connect respectively
Connect first liquid pump and first sample operating unit, second four way solenoid valve connect respectively the second liquid pump and
Second sample operations unit, the first pipeline and the second pipeline connect first four way solenoid valve and described second with parallel form
Four way solenoid valve;First liquid pump passes through first four way solenoid valve, first pipeline, second four-way electromagnetic
Valve connects the second liquid pump;The first sample operating unit by first four way solenoid valve, second pipeline,
Second four way solenoid valve connects the second sample operations unit.
2. the liquid-way system of analysis liquid sample as claimed in claim 1, it is characterised in that first four way solenoid valve is
Two position four-way solenoid valves, including interface A, interface B, interface C, interface D, its unpowered state are that interface A is connected with interface B, connect
Mouth C is connected with interface D, and "on" position is interface A is connected with interface C, interface B is connected with interface D.
3. the liquid-way system of analysis liquid sample as claimed in claim 1, it is characterised in that second four way solenoid valve is
Two position four-way solenoid valves, including interface A, interface B, interface C, interface D, its unpowered state are that interface A is connected with interface B, connect
Mouth C is connected with interface D, and "on" position is interface A is connected with interface C, interface B is connected with interface D.
4. as claimed in claim 1 analysis liquid sample liquid-way system, it is characterised in that first four way solenoid valve with
Alternately switching unpowered and powered state, combination form four kinds of liquid-way system states to second four way solenoid valve, be respectively 0,
0 }, { 1,0 }, { 0,1 }, { 1,1 };The liquid-way system state { 0,0 } refers to first four way solenoid valve and the described 2nd 4
Three-way electromagnetic valve is in unpowered state simultaneously;It is logical that the liquid-way system state { 1,0 } refers to that first four way solenoid valve is in
Electricity condition and second four way solenoid valve is in unpowered state;The liquid-way system state { 0,1 } refers to the described 1st
Three-way electromagnetic valve is in unpowered state and second four way solenoid valve is in "on" position;The liquid-way system state { 1,1 }
Refer to first four way solenoid valve and second four way solenoid valve while be in "on" position.
5. the liquid-way system of analysis liquid sample as claimed in claim 4, it is characterised in that the state { 1,0 } and state
{ 0,1 } it is alternately present.
6. the liquid-way system of analysis liquid sample as claimed in claim 4, it is characterised in that also including the 3rd liquid pump, institute
The 3rd liquid pump is stated with the second sample operations unit to be connected.
7. the liquid-way system of analysis liquid sample as claimed in claim 6, it is characterised in that the state { 1,0 }, state
{ 0,0 }, state { 0,1 }, state { 1,1 } sequentially occur.
8. the liquid-way system of the analysis liquid sample as described in claim 1 to 7 is any, it is characterised in that first pipeline
Internal capacity and second pipeline internal capacity it is equal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720875554.5U CN207007802U (en) | 2017-07-19 | 2017-07-19 | A kind of liquid-way system for analyzing liquid sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720875554.5U CN207007802U (en) | 2017-07-19 | 2017-07-19 | A kind of liquid-way system for analyzing liquid sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207007802U true CN207007802U (en) | 2018-02-13 |
Family
ID=61454168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720875554.5U Expired - Fee Related CN207007802U (en) | 2017-07-19 | 2017-07-19 | A kind of liquid-way system for analyzing liquid sample |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207007802U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107388039A (en) * | 2017-07-18 | 2017-11-24 | 深圳小孚医疗科技有限公司 | A kind of sample analysis liquid-way system based on four way solenoid valve |
| CN109725169A (en) * | 2018-12-26 | 2019-05-07 | 迪瑞医疗科技股份有限公司 | A kind of liquid channel system and its control method of Urine Analyzer |
-
2017
- 2017-07-19 CN CN201720875554.5U patent/CN207007802U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107388039A (en) * | 2017-07-18 | 2017-11-24 | 深圳小孚医疗科技有限公司 | A kind of sample analysis liquid-way system based on four way solenoid valve |
| CN107388039B (en) * | 2017-07-18 | 2019-01-25 | 深圳小孚医疗科技有限公司 | A kind of sample analysis liquid channel system based on four way solenoid valve |
| CN109725169A (en) * | 2018-12-26 | 2019-05-07 | 迪瑞医疗科技股份有限公司 | A kind of liquid channel system and its control method of Urine Analyzer |
| CN109725169B (en) * | 2018-12-26 | 2023-03-14 | 迪瑞医疗科技股份有限公司 | Liquid path system of urine analyzer and control method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN204044056U (en) | For the device of online water quality detection | |
| CN104155422B (en) | Water quality detection pipeline system and method | |
| CN103454439B (en) | A kind of micro-fluidic chip integral type sampling system | |
| CN108362865A (en) | A kind of method and liquid channel system of test secretion | |
| CN105388309A (en) | Automatic and rapid detection method and system for trace iron ions in power plant water vapor and application | |
| CN115932301A (en) | Sample detection method and sample analyzer | |
| CN112161978A (en) | Nutrient salt water quality analyzer | |
| CN109856352A (en) | A kind of water analysis outfit | |
| CN111007010B (en) | Flow path control system and method for soil biological available nitrogen and phosphorus | |
| CN201210146Y (en) | Water quality on-line monitoring system | |
| CN2935123Y (en) | Eight-port valve and eight-port valve conversion sample-handling system | |
| CN206046598U (en) | A kind of breast milk composition analyser pipeline washing device | |
| CN107388039B (en) | A kind of sample analysis liquid channel system based on four way solenoid valve | |
| CN209841668U (en) | Multi-parameter water quality detector | |
| CN111174098A (en) | Water quality analyzer flow path system and method for accurate quantification | |
| CN203265144U (en) | Washing device | |
| CN216594777U (en) | A detection device for the determination of trace iron in water vapor system by forward osmosis concentration method | |
| CN109060930A (en) | A kind of double sample loop sampling systems based on the design of novel eight ways valve | |
| CN211905091U (en) | Detection channel and sampling system of SPR chip | |
| CN205580928U (en) | In -line viscometer | |
| CN208902751U (en) | Quantitative sample injection and cleaning system | |
| CN212083345U (en) | Automatic analysis device for measuring COD in water | |
| CN219533107U (en) | Water quality detection device and system based on micro-fluidic chip | |
| CN211118782U (en) | Flow path system of water quality analyzer | |
| CN207866565U (en) | A kind of integrated quantitative sampling mix reagent device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20211216 Address after: 361000 unit 6, 607, floor 6, Chuangye building, 1302 Jimei Avenue, Jimei District, Xiamen City, Fujian Province Patentee after: Xiamen Xuwu Membrane Technology Co.,Ltd. Address before: 518100 Room 401, block B, building 2, Tianan digital new town, Huangge North Road, Longcheng street, Longgang District, Shenzhen City, Guangdong Province Patentee before: SHENZHEN XIAOFU MEDICAL TECHNOLOGY Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180213 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |