CN211825879U - Liquid path structure of glycosylated hemoglobin - Google Patents
Liquid path structure of glycosylated hemoglobin Download PDFInfo
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- CN211825879U CN211825879U CN201922161220.3U CN201922161220U CN211825879U CN 211825879 U CN211825879 U CN 211825879U CN 201922161220 U CN201922161220 U CN 201922161220U CN 211825879 U CN211825879 U CN 211825879U
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Abstract
The utility model discloses a liquid way structure of glycated haemoglobin, include: the device comprises a motor, an injector, a first reagent bottle, a second reagent bottle, a vacuum chamber, a waste liquid collecting bottle, a dilution bottle, a cleaning sleeve and a sample reaction cup, wherein the injector is respectively connected with the cleaning sleeve, the first reagent bottle, the second reagent bottle and the dilution bottle through pipelines, the cleaning sleeve, the sample reaction cup and the waste liquid collecting bottle are respectively connected with the vacuum chamber through pipelines, the motor is movably connected with the injector, and a waste liquid discharge port is formed in the lower part of the vacuum chamber. When the sample is prepared, the motor drives the injector to move downwards, negative pressure is formed in the injector, and the sample is sucked into the sample needle. During the application of sample, the motor drives the syringe and up moves, pushes out the sample, and when accomplishing application of sample preparation reagent, the syringe moved down, and three-way valve V2, V3 UNICOM reagent bottle because negative pressure effect reagent enters into in the reagent buffer pool. The utility model discloses can accomplish the addition of reagent automatically, dilute, reaction and waste liquid treatment.
Description
Technical Field
The utility model relates to a glycated hemoglobin and blood sugar detect technical field, in particular to glycated hemoglobin's liquid way structure.
Background
At present, a glycosylated hemoglobin detection instrument based on a boric acid affinity chromatography mainly adopts semi-automation, is complex to operate, is easy to make mistakes and has low test flux. Full-automatic detection equipment is required in larger hospitals and central laboratories, and high-throughput automatic detection equipment is required.
Therefore, further improvement of the full-automatic glycosylated hemoglobin detection circuit of the existing boric acid affinity chromatography methodology is needed.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a can accomplish the liquid way structure of adding, diluting, reaction and waste liquid treatment glycated hemoglobin of reagent automatically.
In order to solve the technical problem, the utility model discloses a technical scheme does:
a fluid path structure of glycated hemoglobin, comprising: the device comprises a motor, an injector, a first reagent bottle, a second reagent bottle, a vacuum chamber, a waste liquid collecting bottle, a dilution bottle, a cleaning sleeve and a sample reaction cup, wherein the injector is respectively connected with the cleaning sleeve, the first reagent bottle, the second reagent bottle and the dilution bottle through pipelines, the cleaning sleeve, the sample reaction cup and the waste liquid collecting bottle are respectively connected with the vacuum chamber through pipelines, the motor is movably connected with the injector, and a waste liquid discharge port is formed in the lower part of the vacuum chamber.
Preferably, the syringe includes first sample needle, second sample needle, third sample needle, fourth sample needle, the tip of first sample needle is equipped with first transfusion tube way, first sample needle with wash the cover and pass through first transfusion tube way is connected and is communicated with each other, the tip of second sample needle is equipped with second transfusion tube way, second sample needle with the dilution bottle passes through second transfusion tube way is connected and is communicated with each other, be equipped with first three solenoid valve, fifth three solenoid valve on the second pipeline respectively.
Preferably, still include third three way solenoid valve, third three way solenoid valve includes a first inlet and two first liquid outlets, the both ends of third three way solenoid valve are equipped with third transfusion pipeline, fourth transfusion pipeline, first drainage pipeline respectively, the third sample needle passes through third transfusion pipeline with first inlet is connected and is communicated with each other, one of third three way solenoid valve first liquid outlet passes through fourth transfusion pipeline with second reagent bottle is connected and is communicated with each other, another of third three way solenoid valve first liquid outlet with first drainage pipeline connects.
Preferably, the device further comprises a second three-way electromagnetic valve, wherein a fifth infusion pipeline, a sixth infusion pipeline and a second liquid discharge pipeline are arranged at two ends of the second three-way electromagnetic valve respectively, the fourth sample needle is communicated with the second three-way electromagnetic valve through the fifth infusion pipeline, and the second three-way electromagnetic valve is communicated with the first reagent bottle through the sixth infusion pipeline.
Preferably, the top and the bottom of the cleaning sleeve are respectively provided with a second liquid inlet and a second liquid outlet, the side part of the cleaning sleeve is provided with a first pipeline interface and a second pipeline interface, and the first pipeline interface is connected with the first infusion pipeline.
Preferably, the system further comprises a fourth three-way electromagnetic valve, a first connecting pipe, a second connecting pipe and a third connecting pipe are respectively arranged at two ends of the fourth three-way electromagnetic valve, the first connecting pipe is respectively communicated with the first pipeline interface and the fourth three-way electromagnetic valve, and the fourth three-way electromagnetic valve is communicated with the fifth three-way electromagnetic valve through the third connecting pipe.
Preferably, the device further comprises a sixth three-way electromagnetic valve, wherein a fourth connecting pipe, a fifth connecting pipe and a sixth connecting pipe are respectively arranged at two ends of the sixth three-way electromagnetic valve, the sixth three-way electromagnetic valve is communicated with the cleaning sleeve through the fourth connecting pipe, and the sixth three-way electromagnetic valve is communicated with the sample reaction cup through the fifth connecting pipe.
Preferably, the vacuum chamber further comprises a seventh electromagnetic valve, one end of the seventh electromagnetic valve is provided with a seventh connecting pipe, one end of the seventh electromagnetic valve is communicated with the vacuum chamber through the seventh connecting pipe, and the seventh electromagnetic valve is communicated with the other end of the sixth three-way electromagnetic valve through the sixth connecting pipe.
The utility model has the advantages that:
the utility model adopts the above technical scheme, can accomplish the addition of reagent, dilute, reaction and waste liquid treatment automatically. When the sample is prepared, the motor drives the injector to move downwards, negative pressure is formed in the injector, and the sample is sucked into the sample needle. During the application of sample, the motor drives the syringe and up moves, pushes out the sample, and when accomplishing application of sample preparation reagent, the syringe moved down, and three-way valve V2, V3 UNICOM reagent bottle because negative pressure effect reagent enters into in the syringe reagent buffer pool. When adding the reagent, the injector moves upwards, the three-way valves V2 and V3 are communicated with the reagent outlet, and the reagent is pushed out. During waste liquid treatment, the vacuum chamber moves upwards, the V7 is in a closed state, and the V6 is guided to the reaction tank. When V7 is opened, the negative pressure in the vacuum chamber makes the liquid in the reaction pool enter the vacuum chamber. V7 is then closed, the collection bottle is opened, the vacuum chamber moves downward, and the waste liquid is drained to a waste bottle.
Drawings
Fig. 1 is a schematic structural diagram of an embodiment of a liquid path structure of glycated hemoglobin according to the present invention.
In the figure, 1-syringe, 11-first sample needle, 12-second sample needle, 13-third sample needle, 14-fourth sample needle,
2-vacuum chamber, 3-waste liquid collecting bottle, 4-diluting bottle, 5-cleaning sleeve, 6-sample reaction cup, 7-reagent buffer pool, 8-air valve,
r1-first reagent bottle, R2-second reagent bottle,
v1-a first three-way solenoid valve, V2-a second three-way solenoid valve, V3-a third three-way solenoid valve, V4-a fourth three-way solenoid valve, V5-a fifth three-way solenoid valve, V6-a sixth three-way solenoid valve, and V7-a seventh solenoid valve.
Detailed Description
The following describes the present invention with reference to the accompanying drawings. It should be noted that the description of the embodiments is provided to help understanding of the present invention, but the present invention is not limited thereto. In addition, the technical features related to the embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
As shown in fig. 1, a fluid path structure of glycated hemoglobin includes: the utility model discloses a vacuum chamber 2, the vacuum chamber 2 is equipped with the waste liquid discharge port, motor, syringe 1, first reagent bottle R1, second reagent bottle R2, vacuum chamber 2, waste liquid receiving flask 3, dilution bottle 4, wash cover 5 and sample reaction cup 6, syringe 1 respectively with wash cover 5, first reagent bottle R1, second reagent bottle R2, 4 tube coupling of dilution bottle, wash cover 5, sample reaction cup 6, waste liquid receiving flask 7 respectively with vacuum chamber 2 tube coupling, motor and syringe 1 swing joint, the lower part of vacuum chamber 2.
Specifically, in this embodiment, the syringe 1 is disposed in the reagent buffer 8.
The utility model discloses in the preferred embodiment, syringe 1 includes first sample needle 11, second sample needle 12, third sample needle 13, fourth sample needle 14, the tip of first sample needle 11 is equipped with first transfusion tube way, first sample needle 11 communicates with each other through first transfusion tube way connection with washing cover 5, the tip of second sample needle 12 is equipped with second transfusion tube way, second sample needle 12 communicates with each other through second transfusion tube way connection with dilution bottle 4, be equipped with first three way solenoid valve V1, fifth three way solenoid valve V5 on the second pipeline respectively.
The utility model discloses in the preferred embodiment, still include third three way solenoid valve V3, third three way solenoid valve V3 includes a first inlet and two first liquid outlets, third three way solenoid valve V3's both ends are equipped with the third infusion pipeline respectively, the fourth infusion pipeline, first drainage pipeline, third sample needle 13 is connected with first inlet through the third infusion pipeline and is communicated with each other, a first liquid outlet of third three way solenoid valve V3 is connected with second reagent bottle R2 through the fourth infusion pipeline and is communicated with each other, another first liquid outlet and the first drainage pipeline of third three way solenoid valve V3 are connected.
The utility model discloses in the preferred embodiment, still include second three way solenoid valve V2, second three way solenoid valve V2 both ends are equipped with fifth infusion pipeline, sixth infusion pipeline, second drainage pipeline respectively, and fourth sample needle 14 communicates with each other through being connected of fifth infusion pipeline and second three way solenoid valve V2, and second three way solenoid valve V2 is connected with first reagent bottle R1 through sixth infusion pipeline and communicates with each other.
In the preferred embodiment of the present invention, the top and the bottom of the cleaning sleeve 5 are respectively provided with a second inlet and a second outlet, the side portion of the cleaning sleeve 5 is provided with a first pipeline interface and a second pipeline interface, and the first pipeline interface is connected with a first infusion pipeline.
The utility model discloses in the preferred embodiment, still include fourth three way solenoid valve V4, fourth three way solenoid valve V4's both ends are equipped with first connecting pipe, second connecting pipe, third connecting pipe respectively, and first connecting pipe is connected with first pipeline interface, fourth three way solenoid valve V4 respectively and is communicated with each other, and fourth three way solenoid valve V4 is connected through the third connecting pipe switch-on with fifth three way solenoid valve V4.
The utility model discloses in the preferred embodiment, still include sixth three way solenoid valve V6, the both ends of sixth three way solenoid valve V6 are equipped with fourth connecting pipe, fifth connecting pipe, sixth connecting pipe respectively, and sixth three way solenoid valve V6 communicates with each other through the fourth connecting pipe connection with washing cover 5, and sixth three way solenoid valve V6 communicates with each other through the fifth connecting pipe connection with sample reaction cup 6.
The utility model discloses in the preferred embodiment, still include seventh solenoid valve V7, seventh solenoid valve V7's one end is equipped with the seventh connecting pipe, and seventh solenoid valve V7's one end communicates with each other through the seventh connecting pipe connection with vacuum chamber 2, and seventh solenoid valve V7 communicates with each other through the sixth connecting pipe connection with the other end of sixth three way solenoid valve V6.
Specifically, in this embodiment, an exhaust port is provided at the upper part of the vacuum chamber 2, and an air valve 9 is provided at the exhaust port.
Specifically, in this embodiment, the utility model discloses a theory of operation as follows:
the utility model discloses can accomplish the addition of reagent automatically, dilute, reaction and waste liquid treatment.
When preparing a sample, the motor drives the injector 1 to move downwards, and the sample is sucked into the sample needle when negative pressure is formed in the injector 1.
When the sample is added, the motor drives the injector 1 to move upwards to push out the sample, and the sample adding is completed
When preparing the reagent, the injector 1 moves downwards, the second three-way electromagnetic valve V2 and the third three-way electromagnetic valve V3 are communicated with the reagent bottle, and the reagent enters the reagent buffer pool 8 under the action of negative pressure.
When adding the reagent, the injector 1 moves upwards, the second three-way electromagnetic valve V2 and the third three-way electromagnetic valve V3 are communicated with the reagent outlet, and the reagent is pushed out.
During waste liquid treatment, the vacuum chamber 2 moves upwards, the seventh electromagnetic valve V7 is in a closed state, and the sixth three-way electromagnetic valve V6 is guided to the sample reaction cup. When the seventh electromagnetic valve is opened at V7, the negative pressure in the vacuum chamber 2 acts to make the liquid in the sample reaction cup 6 enter the vacuum chamber 2. Then, the seventh electromagnetic valve V7 is closed, and the vacuum chamber 2 is moved downward to discharge the waste liquid into the waste liquid collecting bottle 3.
The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the described embodiments. It will be apparent to those skilled in the art that various changes, modifications, substitutions and alterations can be made in the embodiments without departing from the principles and spirit of the invention, and the scope of the invention is to be accorded the full scope of the claims.
Claims (8)
1. A liquid path structure of glycated hemoglobin, comprising: the device comprises a motor, an injector, a first reagent bottle, a second reagent bottle, a vacuum chamber, a waste liquid collecting bottle, a dilution bottle, a cleaning sleeve and a sample reaction cup, wherein the injector is respectively connected with the cleaning sleeve, the first reagent bottle, the second reagent bottle and the dilution bottle through pipelines, the cleaning sleeve, the sample reaction cup and the waste liquid collecting bottle are respectively connected with the vacuum chamber through pipelines, the motor is movably connected with the injector, and a waste liquid discharge port is formed in the lower part of the vacuum chamber.
2. The fluid path structure of glycated hemoglobin of claim 1, wherein the injector comprises a first sample needle, a second sample needle, a third sample needle, and a fourth sample needle, wherein a first fluid infusion line is disposed at an end of the first sample needle, the first sample needle is connected to the cleaning sleeve via the first fluid infusion line, a second fluid infusion line is disposed at an end of the second sample needle, the second sample needle is connected to the dilution bottle via the second fluid infusion line, and the second fluid infusion line is respectively provided with a first three-way solenoid valve and a fifth three-way solenoid valve.
3. The liquid path structure of glycated hemoglobin according to claim 2, further comprising a third three-way solenoid valve, wherein said third three-way solenoid valve comprises a first liquid inlet and two first liquid outlets, a third liquid delivery line, a fourth liquid delivery line, and a first liquid discharge line are disposed at two ends of said third three-way solenoid valve, respectively, said third sample needle is connected to and communicated with said first liquid inlet through said third liquid delivery line, one of said first liquid outlets of said third three-way solenoid valve is connected to and communicated with said second reagent bottle through said fourth liquid delivery line, and another of said first liquid outlets of said third three-way solenoid valve is connected to said first liquid discharge line.
4. The fluid path structure of glycated hemoglobin according to claim 2, further comprising a second three-way solenoid valve, wherein a fifth fluid infusion line, a sixth fluid infusion line, and a second fluid drainage line are respectively disposed at two ends of the second three-way solenoid valve, the fourth sample needle is connected to the second three-way solenoid valve through the fifth fluid infusion line, and the second three-way solenoid valve is connected to the first reagent bottle through the sixth fluid infusion line.
5. The liquid path structure of glycated hemoglobin according to claim 2, wherein the top and the bottom of the washing sleeve are respectively provided with a second liquid inlet and a second liquid outlet, and the side of the washing sleeve is provided with a first pipe interface and a second pipe interface, and the first pipe interface is connected to the first liquid conveying pipe.
6. The structure of claim 5, further comprising a fourth three-way solenoid valve, wherein a first connection pipe, a second connection pipe, and a third connection pipe are respectively disposed at two ends of the fourth three-way solenoid valve, the first connection pipe is respectively connected to the first pipeline interface and the fourth three-way solenoid valve, and the fourth three-way solenoid valve is connected to the fifth three-way solenoid valve through the third connection pipe.
7. The fluid path structure of glycated hemoglobin of claim 1, further comprising a sixth three-way solenoid valve, wherein a fourth connection tube, a fifth connection tube, and a sixth connection tube are respectively disposed at two ends of said sixth three-way solenoid valve, said sixth three-way solenoid valve is connected to and communicated with said washing sleeve via said fourth connection tube, and said sixth three-way solenoid valve is connected to and communicated with said sample reaction cup via said fifth connection tube.
8. The fluid path structure of glycated hemoglobin of claim 7, further comprising a seventh electromagnetic valve, wherein a seventh connection tube is disposed at one end of said seventh electromagnetic valve, one end of said seventh electromagnetic valve is connected to and communicates with said vacuum chamber through said seventh connection tube, and said seventh electromagnetic valve is connected to and communicates with the other end of said sixth three-way electromagnetic valve through said sixth connection tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922161220.3U CN211825879U (en) | 2019-12-05 | 2019-12-05 | Liquid path structure of glycosylated hemoglobin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922161220.3U CN211825879U (en) | 2019-12-05 | 2019-12-05 | Liquid path structure of glycosylated hemoglobin |
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| Publication Number | Publication Date |
|---|---|
| CN211825879U true CN211825879U (en) | 2020-10-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201922161220.3U Active CN211825879U (en) | 2019-12-05 | 2019-12-05 | Liquid path structure of glycosylated hemoglobin |
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| CN (1) | CN211825879U (en) |
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Effective date of registration: 20210902 Granted publication date: 20201030 |