CN109718286A - For treating external application type Traditional Chinese medicine composition patch, preparation and its application of fever - Google Patents
For treating external application type Traditional Chinese medicine composition patch, preparation and its application of fever Download PDFInfo
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Abstract
The invention proposes a kind of for treating external application type Traditional Chinese medicine composition patch, preparation and its application of fever, and wherein the component of the Chinese medicine composition includes: radix bupleuri, cape jasmine, gypsum and sweet wormwood.The present invention passes through medicine irritation acupuncture points on the human body, adjust internal organs, qi and blood, yin-yang, with the unexistent response to treatment for the treatment of methods such as intravenous infusion, intramuscular injection, oral, it is unique, significant in efficacy thus to act on, especially to infusion, intramuscular injection or the cureless fever of oral medication, one patch takes effect, and often receives unexpected effect.Fever to just treating in intravenous infusion or intramuscular injection can effectively shorten the course of disease with present invention treatment, reduce intravenous infusion or intramuscular injection number, improve cure rate, reduce recurrence rate.Utilization of the invention, reducing using antibiotic and solve the problems, such as antibody-resistant bacterium and have the certain significance in terms of avoiding hormone abuse problem.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, particularly relate to a kind of for treating the external application type Chinese traditional medicine composition of fever
Object patch, preparation and its application.
Background technique
Fever refers to that pyrogen directly acts on caused by heat-regulating centers, heat center dysfunction or a variety of causes
Heat production is excessive, heat dissipation is reduced, and causing body temperature to increase is more than the situation of normal range (NR).Everyone normal body temperature is slightly different, and
And it is influenced by factors such as time, season, environment, menstruations.It is generally acknowledged that axillary temperature is higher than when oral temperature is higher than 37.5 DEG C
Body temperature difference is as generated heat at 1 DEG C or more between 37 DEG C or one day.Fever is the clinically most common symptom, is progression of disease
Important clinical performance in the process, it is seen that in multi-infection disease and noninfectious disease.Cause the disease of fever very much, such as
Infectious diseases caused by bacterium, virus, fungi, mycoplasma etc.；Leukaemia, malignant histiocytosis, malignant lymphoma, colon
Cancer, primary hepatoma etc.；Drug fever, rheumatic fever etc..Systemic loupus erythematosus (SIE), dermatomyositis, the more arteries of nodositas
Scorching, mixed connective tissue disease (MCTD, hyperthyroidism, thyroid crisis etc.；Serious dehydration or bleeding, thermoplegia,
Heatstroke, fracture, large-area burns, cerebral hemorrhage, craniocerebral trauma, status epilepticus, heart failure, visceral vessel infraction, tissue
Necrosis etc..As long-term, frequently fever not only influences work, rest or even threat to life.With the worsening of air environment,
The clinical incidence generated heat in recent years has the tendency that constantly rising.Currently, there are many kinds for the drug for the treatment of fever, such as use needle
Agent, Western medicine, Chinese medicine, Chinese patent drug etc., these drugs play certain effect in terms for the treatment of fever, but there is also certain
Deficiency, first is that since prolonged use antibiotic can generate side effect；Second is that increasing patient suffering using injection, it was easy
Quick, side effect is big, and patient is not easily accepted by；Third is that most people, which does not like, takes or refuse medication object, thus give treatment heating tape
Difficulty.The externally applied plaster of many kinds for the treatment of fevers is also disclosed in the prior art, disadvantage is that: first is that general only single
One ground is effective to the fever of a certain seed type, and invalid to other types of fever；Second is that cure rate is lower.
Summary of the invention
The invention proposes a kind of external application type Traditional Chinese medicine composition patch, the method generated heat by particular acupoint application treatment.
The technical scheme of the present invention is realized as follows:
It is a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, the component of the Chinese medicine composition includes:
Radix bupleuri, cape jasmine, gypsum and sweet wormwood.
Radix bupleuri: mild-natured, bitter enters liver, gallbladder channel.Clearind deficient heat Chinese medicine.Function: saturating table purges heat.It is past for cold, fever, fever and chills
Come.Modern pharmacological research proves: radix bupleuri includes 1, antipyretic, antipyretic effect.Main component: saikoside, sapogenin A, volatilization
Oil.Volatile oil acts on strong, small toxicity.Mechanism: act on hypothalamus heat-regulating centers → inhibition cAMP generation or release →
Body temperature set point is inhibited to move up → temperature decline；2, calm, analgesia, antibacterial action；3, antivirus action, infected by influenza have by force
Strong inhibiting effect；4. promoting immune function.Bupleurum chinense polysaccharide → increase Kupffer Cell phagocytic function, enhances natural killer cells
Function improves virus-specific antibodies titre, improves lymphocyte transformation rate and cutaneous delayed-type hypersensitivity.
Cape jasmine: cold in nature, bitter, return heart, lung, tri-jiao channel.Function: purging intense heat relieving restlessness, removing pattogenic heat from the blood and toxic material from the body.The heart is disturbed suitable for 1, heat
Mind: fever caused by exogenous pathogenic factors, the evil strongly fragrant part of the body cavity above the diaphragm housing the heart and lungs, ambition unhappiness egersis.2, fire toxin is flourishing, high fever agitation or even delirious speech.Modern pharmacological research card
Bright: the alcohol extract of cape jasmine and different processed products has antipyretic effect, stronger with antipyretic effect of raw cape jasmine, and ursolic acid is cape jasmine drop
Warm calm one of effective component.Ursolic acid content is substantially reduced after frying charcoal, therefore the refrigeration function of stir-baked FRUCTUS GARDENIAE obviously weakens, burnt Cape jasmine
It is sub then do not have.
Gypsum: it is cold in nature, it is acrid flavour, sweet, enter lung, stomach meridian.Function: expelling pathogenic factors from muscles for clearing heat, relieving restlessness quenches the thirst, is clearing heat and detoxicating, purging intense heat.It is modern
Pharmacological research proves: gypsum have the function of it is antipyretic, quench one's thirst, play the role of adjust immune system；It can inhibit caused by vigorous interior heat
Hypophysis, adrenal gland, salivary gland, prostate, pancreas, testicular function are hyperfunction；Keep spleen and thymus function hyperfunction.
Sweet wormwood: it is cold in nature, it is bitter, pungent, return liver, gallbladder channel.For fever due to yin deficiency key medicine.Function: clear abnormal heat, cool blood are solved except steaming
Heat, preventing malaria.It generates heat for summer-heat evil, fever due to yin deficiency, night fever abating at dawn, hectic fever due to yin labor heat, malaria fever and chills.The product bitter-cold herbs expelling heat, Xin Xiangtou
It dissipates, it is kind to make yin that latent heat be divided to reach outer dissipate thoroughly.Modern pharmacological research proves: sweet wormwood includes 1, refrigeration function；2, Immunie-Modulating: can
The conversion ratio for improving lymphocyte, promotes the immunization of body cell；3, resisting pathogenic microbes acts on: sweet wormwood water decoction is to more
Kind bacterium has inhibiting effect.
Above all medicine compatibilities, medication is simplified, prescription is rigorous, is complemented each other, is brought out the best in each other.Clearing heat-fire detoxication is strong,
It gets instant result, has no toxic side effect to body, it being capable for the treatment of both manifestation and root cause of disease.
Parts by weight are as follows in the component and component of the Chinese medicine composition as a preferred technical solution:
Radix bupleuri 8-12；Cape jasmine 8-12；Gypsum 8-12；Sweet wormwood 8-12.
Parts by weight are as follows in the component and component of the Chinese medicine composition as a preferred technical solution:
Radix bupleuri 9-11；Cape jasmine 9-11；Gypsum 9-11；Sweet wormwood 9-11.
Parts by weight are as follows in the component and component of the Chinese medicine composition as a preferred technical solution:
Radix bupleuri 8；Cape jasmine 9；Gypsum 11；Sweet wormwood 12.
It is a kind of for treat fever external application type Traditional Chinese medicine composition patch preparation method, including,
Radix bupleuri, cape jasmine, gypsum, sweet wormwood are ground, mixture of powders is obtained；
Using above-mentioned mixture of powders as dressing, patch is made to obtain the final product.
Pharmaceutically acceptable auxiliary material is added in the mixture of powders as a preferred technical solution, then patch is made
Agent.
Above-mentioned patch is attached to SHENQUE acupoint (navel) or vola Yongquan acupoint, that is, can reach the effect for the treatment of fever.
The present invention is according to the principle of motherland's medicine inner disease outer treat, using the pure Chinese medicine with clearing heat and detoxicating the effect of bringing down a fever,
It spreads on specific acupuncture point, by medicine irritation acupuncture points on the human body absorbing transmission from skin, for treating bacterium, virus, fungi, mycoplasma etc.
Caused fever caused by infection；Drug fever, rheumatic fever；Systemic loupus erythematosus (SIE), dermatomyositis, nodular polyarteritis, mixing
Property connective tissue disease (MCTD, hyperthyroidism, thyroid crisis, serious dehydration or bleeding, thermoplegia, heatstroke, bone
Folding, large-area burns, cerebral hemorrhage, craniocerebral trauma, status epilepticus, heart failure, visceral vessel infraction, tissue necrosis etc. draw
The fever risen.It clearing heat and detoxicating can bring down a fever, improve symptom rapidly to achieve the purpose that cure fever, and without any side effects.
It is a kind of Novel external patch that tcm therapy is combined with modern high technology, has and " has no toxic side effect, is safe and efficient, is square
Just, simultaneous treatment of principal and subordinate symptoms, build up health " the features such as.Compared with prior art, it has the advantage that
1. the present invention adjusts internal organs, qi and blood, yin-yang by medicine irritation acupuncture points on the human body, there is the treatment such as intravenous infusion, intramuscular injection, oral
The unexistent response to treatment of method, thus effect is unique, significant in efficacy, especially to infusion, intramuscular injection or oral medication obstinate
Fever, one patch take effect, often receive unexpected effect.
2. the fever pair just treated in intravenous infusion or intramuscular injection, the course of disease can be effectively shortened with present invention treatment, reduces intravenous infusion or flesh
Number is infused, cure rate is improved, reduces recurrence rate.Utilization of the invention is reducing using antibiotic and is solving the problems, such as antibody-resistant bacterium
And it avoids having the certain significance in terms of hormone abuse problem.
3. inventive formulation is exquisite, the etiology and pathogenesis of physiological and pathological feature and fever disease to human body is with strong points, effect
Fruit is unique.
4. stimulation and its toxic side effect of the oral medicine to internal organs such as stomach, intestines, liver, kidneys can be reduced or avoided in the present invention；It reduces
Or intravenous infusion and intramuscular injection is avoided to treat bring risk, damaging and painful property, have the advantages that not destroy human normal tissue.
5. the fear needle occurred when the oral medicine feed of the changeable children of the present invention or infusion, intramuscular injection refuses to take medicine, cries and screams, compliance is poor,
The status for enabling parent's worries is very suitable to the patient of paediatrics.
6, the present invention is easy to use, easy to carry to treatment fever short treating period, quick, is suitble to crowd extensive.
Specific embodiment
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common
Technical staff's every other embodiment obtained without creative efforts belongs to the model that the present invention protects
It encloses.
Embodiment 1
It is a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, which is made of the following raw material:
Radix bupleuri 11g；Cape jasmine 8g；Gypsum 12g；Sweet wormwood 10g.
Preparation method, comprising:
After taking radix bupleuri, cape jasmine, gypsum and sweet wormwood to pulverize, vaseline is added, is then placed in non-woven fabrics patch and patch is made
Agent.
Embodiment 2
It is a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, which is made of the following raw material:
Radix bupleuri 8g；Cape jasmine 9g；Gypsum 11g；Sweet wormwood 12g.
Preparation method, comprising:
After taking radix bupleuri, cape jasmine, gypsum and sweet wormwood to pulverize, vaseline is added, is then placed in non-woven fabrics patch and patch is made
Agent.
Embodiment 3
It is a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, which is made of the following raw material:
Radix bupleuri 9g；Cape jasmine 10g；Gypsum 10g；Sweet wormwood 11g.
Preparation method, comprising:
After taking radix bupleuri, cape jasmine, gypsum and sweet wormwood to pulverize, vaseline is added, is then placed in non-woven fabrics patch and patch is made
Agent.
Embodiment 4
It is a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, which is made of the following raw material:
Radix bupleuri 10g；Cape jasmine 12g；Gypsum 9g；Sweet wormwood 9g.
Preparation method, comprising:
After taking radix bupleuri, cape jasmine, gypsum and sweet wormwood to pulverize, vaseline is added, is then placed in non-woven fabrics patch and patch is made
Agent.
Embodiment 5
The observation of curative effect of Chinese medicine composition of the present invention.
300 fever patients are randomly divided into experimental group and control group, every group 150, respectively prepared by Application Example
It the patch of Chinese medicine composition and takes ibuprofen suspension and is treated.
Treatment method: the patch is attached to SHENQUE acupoint (navel) from experimental group daily morning, is removed before sleeping；It will be described before sleeping
Patch is attached to biped bottom Yongquan acupoint, removes from morning, twice a day pastes.Stop other western medicines in treatment during treatment.Control group: body
Temperature just eats ibuprofen suspension more than 38.5 DEG C, is at least spaced 4-6 hours or more between, is no more than within 24 hours
4 times, stop other western medicines in treatment during treatment.
Observation of curative effect: the present invention clinically achieves preferable curative effect, in 150 fever patients, the external application present invention
Described in embodiment 2 after patch 3 days, 140 are cured, cure rate accounts for 93.3%, improves 8, obvious effective rate accounts for 0.05%, total effective rate
It is 98.7%, invalid 2, inefficiency accounts for 1.7%.Control group cure rate is 75%, and two groups of cure rates relatively have significant difference.
Embodiment 6
The clinical observation on the therapeutic effect of patch of the present invention:
1, Zhao, male, 1 years old, first visit on June 6 in 2018.Fever, cough 2 days, diagnosis: acute bronchitis takes orally head
Spore gram oxime particle, ambroxol hydrochloride oral liquid and ibuprofen suspension generate heat persistent, use 1 patch of the embodiment of the present invention
The patch is attached to SHENQUE acupoint (navel) from daily morning, removed before sleeping by treatment；The patch is attached to biped ground swell spring before sleeping
Cave is removed from morning, is twice a day pasted.When quotidian fever moves back, mitigation of coughing, continuation after treatment according to the above method is fullyed recover from an illness after 3 days
More.
2, Sun, female, 5 years old, the first visit on the 21st of August in 2018.Fever is repeatedly more than half a month, and diagnosis: summer is hot, dead point cephalo gram
Oxime injection, vitamin C injection, oral traditional Chinese medicine treatment, still lasting low-heat, based on afternoon, evening, spirit is poor, has no appetite.
It is treated using 2 patch of the embodiment of the present invention, the patch is attached to SHENQUE acupoint (navel) from daily morning, is removed before sleeping；Sleep preceding incite somebody to action
The patch is attached to biped bottom Yongquan acupoint, removes from morning, twice a day pastes.When quotidian fever moves back, spirit improves；Continue by above-mentioned side
Method after treatment is fully recovered after 3 days, is not recurred again.
3, Qian, male, 33 years old, the first visit on the 28th of August in 2018.Pharyngalgia, pharynx itch, generate heat 2~3 days, diagnose: acute sore throat
Inflammation, takes Pudilan anti-inflammatory oral solution, Qingkailing granule certainly, and remission is unobvious.It is treated using 3 patch of the embodiment of the present invention,
The patch is attached to SHENQUE acupoint (navel) from daily morning, is removed before sleeping；The patch is attached to biped bottom Yongquan acupoint, morning before sleeping
It rises and removes, twice a day paste.Fever in second day is moved back, and pharyngalgia swallows improvement of itching, and is continued after treatment according to the above method, is fullyed recover from an illness after 3 days
More.
4, Zhang, female, nine months, the first visit on the 2nd of September in 2018.Fever, asthma, gurgling with sputum 5 days, diagnosis are as follows: bronchus
Pneumonia was generated heat still lasting, gurgling with sputum is obvious, slightly pants in Yiwu City central hospital hospitalization 5 days.In hospitalization
It is treated simultaneously using 4 patch of the embodiment of the present invention, the patch is attached to SHENQUE acupoint (navel) from daily morning, is removed before sleeping；It sleeps
It is preceding that the patch is attached to biped bottom Yongquan acupoint, it removes from morning, twice a day pastes.That night fever is moved back, and asthma, gurgling with sputum subtract
Gently；Continue to use after treatment of the present invention according to the above method, discharge of fully recovering after hospitalization 3 days.
5, certain is thanked, male, 16 years old, the first visit on the 3rd of September in 2018.Fever, cough 3 days, diagnosis are as follows: bronchitis, in Yiwu City
Certain clinic dead point Piperacillin sulbactam injection after ambroxol hydrochloride injection 2 days, generates heat persistent.Family members withdraw the previous remark
It takes traditional Chinese medicine, and uses 1 patch of the embodiment of the present invention, the patch is attached to SHENQUE acupoint (navel) from daily morning, is removed before sleeping；It sleeps
It is preceding that the patch is attached to biped bottom Yongquan acupoint, it removes from morning, twice a day pastes.That night makes according to the above method without fever, continuation
It is disappeared with symptom behind the present invention and oral traditional Chinese medicine 3 days.
6, Xiong, male, 9 years old, the first visit on the 5th of September in 2018.Having a stuffy nose, recurrent exerbation April is remaining, generates heat 2 days, diagnosis are as follows: allergy
Property rhinitis, acute upper respiratory infection, give oral traditional Chinese medicine, antiallergic, ibuprofen suspension intermittent treatment, fever do not move back, nose
Plug is obvious.It is treated using 1 patch of the embodiment of the present invention, the patch is attached to SHENQUE acupoint (navel) from daily morning, is removed before sleeping；
The patch is attached to biped bottom Yongquan acupoint before sleeping, removes from morning, twice a day pastes.That night fever is moved back, further consultation after 3 days, hair
Heat is not repeatedly.
7, it is blue certain, female, 29 years old, the first visit on the 19th of September in 2018.Fever 7 days, diagnosis are as follows: lower-left pneumonia, in Yiwu City Chinese medicine
Institute's hospitalization is given intravenous drip, atomization and oral traditional Chinese medicine treatment, fever and is not moved back repeatedly, and for highest body temperature up to 40 DEG C, phlegm Huang is thick not
Easy expectoration.Add 2 patch of the embodiment of the present invention on the basis of original treatment: the patch being attached to SHENQUE acupoint (tripe from daily morning
Navel), it is removed before sleeping；The patch is attached to biped bottom Yongquan acupoint before sleeping, removes from morning, twice a day pastes.Second quotidian fever is
It moves back, continues to give the present invention and after former treatment 3 days, fever is without repeatedly.
8, Zhu, female, 2 years old, first visit on October 11 in 2018.Fever 5 days, diagnosis are as follows: acute suppurative tonsillitis,
Yiwu City healthcare hospital for women & children intravenous drip amoxicillin and clavulanate potassium injection 5 days, persistent, pharyngalgia of generating heat are received less, essence
Angel is treated using 3 patch of the embodiment of the present invention: the patch being attached to SHENQUE acupoint (navel) from daily morning, is removed before sleeping；It sleeps
It is preceding that the patch is attached to biped bottom Yongquan acupoint, it removes from morning, twice a day pastes.That night fever is moved back, and Gong of the present invention is continued to use
Admittedly treatment 2 days, no fever.
9, leaf, male, 12 years old, first visit on November 11 in 2018.There are more than 10 years of allergic asthma history, is induced after catching a cold recently
Hospital outpatient intravenous drip antibiotic, hormone and nebulae inhalation, mouth are recovered in Yiwu City in asthma, fever, asthma 3 days when going to a doctor
Bronchial spasmolytic agent is taken, symptom slightly improves, and still generates heat, pants, discomfort uncomfortable in chest.It is treated using 3 patch of the embodiment of the present invention: daily
The patch is attached to SHENQUE acupoint (navel) from morning, is removed before sleeping；The patch is attached to biped bottom Yongquan acupoint before sleeping, is taken from morning
Under, twice a day paste.That night fever is moved back, and still has slight asthma, without uncomfortable in chest, stopped within second day intravenous drip antibiotic and is swashed
Element is continued after being cooperated nebulae inhalation 3 days using the present invention according to the above method, and all symptoms disappear.
10, Lee, female, 9 months, first visit on November 16 in 2018.More than 10 day of gurgling with sputum, fever 2 days, diagnosis are as follows: asthma
Breath property bronchitis, after Yiwu City healthcare hospital for women & children hospitalization 10 days, because of intravenous drip difficulty, family members go to our hospital and ask
It examines, is treated using 4 patch of the embodiment of the present invention: the patch being attached to SHENQUE acupoint (navel) from daily morning, is removed before sleeping；Before sleeping
The patch is attached to biped bottom Yongquan acupoint, removes from morning, twice a day pastes.That night fever is moved back, and gurgling with sputum is unobvious, after
It is continuous to be sticked 3 days by this method, cooperate symptom after nebulae inhalation to disappear, continues to strengthen treatment 2 days, symptom does not recur again.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (7)
1. a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, which is characterized in that the group subpackage of the Chinese medicine composition
It includes:
Radix bupleuri, cape jasmine, gypsum and sweet wormwood.
2. according to claim 1 a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, which is characterized in that institute
It is as follows to state parts by weight in the component and component of Chinese medicine composition:
Radix bupleuri 8-12；Cape jasmine 8-12；Gypsum 8-12；Sweet wormwood 8-12.
3. according to claim 1 or 2 a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, feature exists
In parts by weight are as follows in the component and component of the Chinese medicine composition:
Radix bupleuri 9-11；Cape jasmine 9-11；Gypsum 9-11；Sweet wormwood 9-11.
4. according to claim 1 or 2 a kind of for treating the external application type Traditional Chinese medicine composition patch of fever, feature exists
In parts by weight are as follows in the component and component of the Chinese medicine composition:
Radix bupleuri 8；Cape jasmine 9；Gypsum 11；Sweet wormwood 12.
5. a kind of for treating the preparation method of the external application type Traditional Chinese medicine composition patch of fever characterized by comprising
Radix bupleuri, cape jasmine, gypsum, sweet wormwood are ground, mixture of powders is obtained；
Using above-mentioned mixture of powders as dressing, patch is made.
6. it is according to claim 5 a kind of for treating the preparation method of the external application type Traditional Chinese medicine composition patch of fever,
It is characterized in that, pharmaceutically acceptable auxiliary material is added in the mixture of powders, then patch is made.
7. a kind of external application type Chinese medicine composition patch for treating fever according to any claim from 1 to 6
Agent, which is characterized in that the patch is attached to umbilical region or vola Yongquan acupoint.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110755544A (en) * | 2019-05-17 | 2020-02-07 | 罗开堂 | Fever-reducing patch for children |
| CN110898176A (en) * | 2019-12-06 | 2020-03-24 | 冼启福 | Traditional Chinese medicine composition for treating cold |
| CN111671807A (en) * | 2020-07-20 | 2020-09-18 | 玉林师范学院 | External traditional Chinese medicine composition for children defervescence, gel plaster and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110755544A (en) * | 2019-05-17 | 2020-02-07 | 罗开堂 | Fever-reducing patch for children |
| CN110898176A (en) * | 2019-12-06 | 2020-03-24 | 冼启福 | Traditional Chinese medicine composition for treating cold |
| CN111671807A (en) * | 2020-07-20 | 2020-09-18 | 玉林师范学院 | External traditional Chinese medicine composition for children defervescence, gel plaster and preparation method thereof |
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