CN109718245A - A kind of collyrium and preparation method thereof for asthenopia of releiving - Google Patents
A kind of collyrium and preparation method thereof for asthenopia of releiving Download PDFInfo
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- CN109718245A CN109718245A CN201910212382.7A CN201910212382A CN109718245A CN 109718245 A CN109718245 A CN 109718245A CN 201910212382 A CN201910212382 A CN 201910212382A CN 109718245 A CN109718245 A CN 109718245A
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- collyrium
- sodium
- asthenopia
- releiving
- distilled water
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Abstract
The invention discloses a kind of collyrium of asthenopia of releiving, the component including following weight percentage: 6 0.05-5.0% of water-soluble (vitamin) B；Sodium chondroitin sulfate 0.05-0.15%；Sodium hyaluronate 1.0-5.0%；EDETATE SODIUM 0.1-0.35%；Sodium chloride 0.7-0.9%；Taurine 0.2-0.4%；Boric acid 0.1-0.3%；Borax 0.1-0.3%；Tween 80 0.25-1.0%；Freshener 1.0-2.0%；Sterilization antiseptic 0.02-0.35%；Surplus is distilled water.A kind of collyrium for asthenopia of releiving of the present invention, using sodium hyaluronate as lubrication humectant, viscosity with higher and lubricity, assign the good mobility of collyrium, there is good biocompatibility with eyeball surface, enhance comfort and lubrication sense, moisture retention is good, the senses of discomfort such as eye is dry and astringent can be alleviated for a long time, refrigerant effect can be played using freshener, alleviate eye distending pain problem, collyrium of the invention, visual fatigue can be effectively relieved, accelerate metabolism, enhancing eye resistance, antibacterial and other effects.
Description
[technical field]
The present invention relates to the technical field of medicine, in particular to a kind of collyriums and preparation method thereof for asthenopia of releiving.
[background technique]
With the continuous development of present society and electronics technology, study and work pressure is also increasing, most direct table
It is now exactly gradually to increase time of contact of people and electronic product, so that eyes are for a long time and mobile phone screen, computer screen, projection
Equipment contact, keeps eyes dog-tired, the problems such as dry and astringent, pain, eyeball inflammation often occurs.People would generally select collyrium or
Eye drops alleviates the fatigue problem of eye, and collyrium on the market mainly plays wetting action to eyes, and subsidiary some anti-inflammatory,
The functions such as refrigerant.But collyrium moistening effect at present on the market is lower, usually washes after eye or eye drip, in the short time
Interior eyeball again can be dry and astringent.Collyrium or eye drops with functions such as anti-inflammatory, antiallergy or vessel retractions, generally use antibiotic
Equal drugs, side effect is strong, normal people can be led to the problem of it is uncomfortable, it is stronger to the irritation of eyeball.Therefore, it is necessary to
It is proposed the good collyrium of a kind of strong applicability, lubrication moisture retention.
[summary of the invention]
It is an object of the invention to overcome above-mentioned the deficiencies in the prior art, a kind of collyrium of asthenopia of releiving is provided,
Aim to solve the problem that collyrium applicability in the prior art is low, irritation is strong, the technical problem of lubrication moisturizing difference.
To achieve the above object, the invention proposes a kind of collyriums of asthenopia of releiving, including following weight percent to contain
The component of amount:
Preferably, including the component of following weight percentage:
Preferably, including the component of following weight percentage:
The invention also provides a kind of collyrium preparation methods of asthenopia of releiving, and include the following steps:
S1, suitable distilled water is taken, sodium hyaluronate is added in distilled water, it is appropriate to dissolve by heating, it is uniformly mixed, to solution
It is spare after cooling；
S2, suitable distilled water is separately taken, sodium chondroitin sulfate, EDETATE SODIUM, sodium chloride, taurine, boric acid, boron is added
Sand, Tween 80 and sterilization antiseptic, it is appropriate to dissolve by heating, it is uniformly mixed, when solution is cooled to 38 DEG C or less, adds water-soluble
Spare sodium hyaluronate solution is added after mixing evenly in property vitamin B6 and freshener, and is uniformly mixed, and adds distilled water extremely
Full dose；
S3, the solution aseptic filtration that will be prepared through S2, filtrate packing.
Preferably, the freshener is one or both of menthol, propylene glycol.
Preferably, the freshener includes menthol and propylene glycol, the amount ratio of menthol and propylene glycol is 1:1.
Preferably, the sterilization antiseptic uses the mixture of ethyl hydroxy benzoate sodium and methyl hydroxybenzoate sodium.
Preferably, the amount ratio of the ethyl hydroxy benzoate sodium and methyl hydroxybenzoate sodium is 1:1.
Beneficial effects of the present invention: compared with prior art, a kind of collyrium for asthenopia of releiving provided by the invention is adopted
It uses sodium hyaluronate as lubrication humectant, viscosity with higher and lubricity, the good mobility of collyrium is assigned, with eyeball
Surface has good biocompatibility, enhancing comfort and lubrication sense, and moisture retention is good, can alleviate for a long time eye it is dry and astringent it is equal not
Suitable sense, refrigerant effect can be played using freshener, alleviated eye distending pain, be added to sodium chondroitin sulfate, can protect cornea,
Antiseptic content is few, reduces the stimulation to eyeball, and visual fatigue can be effectively relieved in collyrium of the invention, accelerates metabolism, increases
Strong eye resistance, antibacterial and other effects.
Feature and advantage of the invention will be described in detail by embodiment.
[specific embodiment]
In order to make the objectives, technical solutions and advantages of the present invention clearer, below by embodiment, to the present invention into
Row is further described.However, it should be understood that the specific embodiments described herein are merely illustrative of the present invention, and do not have to
In limiting the scope of the invention.In addition, in the following description, descriptions of well-known structures and technologies are omitted, to avoid need not
Obscure idea of the invention in strategic point.
Embodiment one,
A kind of collyrium for asthenopia of releiving, the component including following weight percentage:
The collyrium is prepared by following steps:
S1, suitable distilled water is taken, sodium hyaluronate is added in distilled water, it is appropriate to dissolve by heating, it is uniformly mixed, to solution
It is spare after cooling.
S2, suitable distilled water is separately taken, sodium chondroitin sulfate, EDETATE SODIUM, sodium chloride, taurine, boric acid, boron is added
Sand, Tween 80, ethyl hydroxy benzoate sodium and methyl hydroxybenzoate sodium, it is appropriate to dissolve by heating, it is uniformly mixed, is cooled to 38 DEG C or less to solution
When, water-soluble (vitamin) B 6 and menthol are added, after mixing evenly, spare sodium hyaluronate solution is added, and be uniformly mixed,
Distilled water is added to full dose.
S3, the solution aseptic filtration that will be prepared through S2, filtrate packing.
Embodiment two,
A kind of collyrium for asthenopia of releiving, the component including following weight percentage:
The collyrium preparation method, includes the following steps:
S1, suitable distilled water is taken, sodium hyaluronate is added in distilled water, it is appropriate to dissolve by heating, it is uniformly mixed, to solution
It is spare after cooling.
S2, suitable distilled water is separately taken, sodium chondroitin sulfate, EDETATE SODIUM, sodium chloride, taurine, boric acid, boron is added
Sand, Tween 80, ethyl hydroxy benzoate sodium and methyl hydroxybenzoate sodium, it is appropriate to dissolve by heating, it is uniformly mixed, is cooled to 38 DEG C or less to solution
When, water-soluble (vitamin) B 6, menthol, propylene glycol are added, after mixing evenly, spare sodium hyaluronate solution is added, and mix
It closes uniformly, adds distilled water to full dose.
S3, the solution aseptic filtration that will be prepared through S2, filtrate packing.
Embodiment three,
A kind of collyrium for asthenopia of releiving, the component including following weight percentage:
The collyrium preparation method, includes the following steps:
S1, suitable distilled water is taken, sodium hyaluronate is added in distilled water, it is appropriate to dissolve by heating, it is uniformly mixed, to solution
It is spare after cooling.
S2, suitable distilled water is separately taken, sodium chondroitin sulfate, EDETATE SODIUM, sodium chloride, taurine, boric acid, boron is added
Sand, Tween 80, ethyl hydroxy benzoate sodium and methyl hydroxybenzoate sodium, it is appropriate to dissolve by heating, it is uniformly mixed, is cooled to 38 DEG C or less to solution
When, water-soluble (vitamin) B 6, menthol, propylene glycol are added, after mixing evenly, spare sodium hyaluronate solution is added, and mix
It closes uniformly, adds distilled water to full dose.
S3, the solution aseptic filtration that will be prepared through S2, filtrate packing.
A kind of collyrium of asthenopia of releiving proposed by the invention, lubrication moisture retention is strong, and visual fatigue can be effectively relieved, delay
Xie Gan itches the problems such as sour and astringent, accelerates metabolism, enhancing eye resistance, antibacterial effect.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modification, equivalent replacement or improvement etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (8)
1. a kind of collyrium for asthenopia of releiving, it is characterised in that: the component including following weight percentage:
2. a kind of collyrium for asthenopia of releiving as described in claim 1, it is characterised in that: including following weight percentage
Component:
3. a kind of collyrium for asthenopia of releiving as described in claim 1, it is characterised in that: including following weight percentage
Component:
4. a kind of collyrium of asthenopia of releiving as described in claims 1 to 3 any one, it is characterised in that: the collyrium
Preparation method include the following steps:
S1, suitable distilled water is taken, sodium hyaluronate is added in distilled water, it is appropriate to dissolve by heating, it is uniformly mixed, it is cooling to solution
It is spare afterwards；
S2, suitable distilled water is separately taken, sodium chondroitin sulfate is added, EDETATE SODIUM, sodium chloride, taurine, boric acid, borax, spits
Temperature 80 and sterilization antiseptic, it is appropriate to dissolve by heating, it is uniformly mixed, when solution is cooled to 38 DEG C or less, adds water soluble vitamin
Raw element B6 and freshener are added spare sodium hyaluronate solution, and be uniformly mixed, add distilled water to full dose after mixing evenly；
S3, the solution aseptic filtration that will be prepared through S2, filtrate packing.
5. a kind of collyrium of asthenopia of releiving as described in claims 1 to 3 any one, it is characterised in that: described is clear
Cool dose is one or both of menthol, propylene glycol.
6. a kind of collyrium for asthenopia of releiving as claimed in claim 5, it is characterised in that: the freshener includes peppermint
The amount ratio of brain and propylene glycol, menthol and propylene glycol is 1:1.
7. a kind of collyrium of asthenopia of releiving as described in claims 1 to 3 any one, it is characterised in that: described kills
Bacterium preservative uses the mixture of ethyl hydroxy benzoate sodium and methyl hydroxybenzoate sodium.
8. a kind of collyrium for asthenopia of releiving as claimed in claim 7, it is characterised in that: the ethyl hydroxy benzoate sodium and hydroxyl
The amount ratio of benzene methyl sodium is 1:1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910212382.7A CN109718245A (en) | 2019-03-20 | 2019-03-20 | A kind of collyrium and preparation method thereof for asthenopia of releiving |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910212382.7A CN109718245A (en) | 2019-03-20 | 2019-03-20 | A kind of collyrium and preparation method thereof for asthenopia of releiving |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973554A (en) * | 2020-09-03 | 2020-11-24 | 浙江目中明生物科技有限公司 | Eye-protecting liquid |
| CN112206240A (en) * | 2020-10-15 | 2021-01-12 | 郑州市新视明科技工程有限公司 | Eyewash for relieving visual fatigue |
| CN114177280A (en) * | 2021-12-17 | 2022-03-15 | 上海卫康光学眼镜有限公司 | Eye lotion containing stable antioxidant enzyme and preparation method thereof |
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| CN1628695A (en) * | 2004-09-01 | 2005-06-22 | 凌沛学 | Eye lotion containing hyaluronic acid and hyaluronic salt and method for making same |
| CN1839834A (en) * | 2006-01-26 | 2006-10-04 | 崔彬 | Eye medicine for preventing and treating asthenopia and allergy |
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2019
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| CN1628695A (en) * | 2004-09-01 | 2005-06-22 | 凌沛学 | Eye lotion containing hyaluronic acid and hyaluronic salt and method for making same |
| CN1839834A (en) * | 2006-01-26 | 2006-10-04 | 崔彬 | Eye medicine for preventing and treating asthenopia and allergy |
| CN101129698A (en) * | 2007-09-18 | 2008-02-27 | 陈苏莉 | Eye drops containing turmeric extractive and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973554A (en) * | 2020-09-03 | 2020-11-24 | 浙江目中明生物科技有限公司 | Eye-protecting liquid |
| CN112206240A (en) * | 2020-10-15 | 2021-01-12 | 郑州市新视明科技工程有限公司 | Eyewash for relieving visual fatigue |
| CN114177280A (en) * | 2021-12-17 | 2022-03-15 | 上海卫康光学眼镜有限公司 | Eye lotion containing stable antioxidant enzyme and preparation method thereof |
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Application publication date: 20190507 |