CN109692262A - A kind of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal Chinese medicine composition - Google Patents

A kind of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal Chinese medicine composition Download PDF

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CN109692262A
CN109692262A CN201910084508.7A CN201910084508A CN109692262A CN 109692262 A CN109692262 A CN 109692262A CN 201910084508 A CN201910084508 A CN 201910084508A CN 109692262 A CN109692262 A CN 109692262A
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powder
parts
chinese medicine
medicine composition
root
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陈碧强
曹伟
李玉洁
郭宗碧
潘峰超
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FUJIAN HUITIAN BIOLOGICAL PHARMACEUTICAL Co Ltd
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FUJIAN HUITIAN BIOLOGICAL PHARMACEUTICAL Co Ltd
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

The present invention provides the Chinese medicine composition of a kind of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal, belongs to technical field of traditional Chinese medicines.The Chinese medicine composition includes the component of following parts by weight: 10~400 parts of Paris polyphylla powder drapes over one's shoulders 2~50 parts of numb grass meal, 1~20 part of white clouds pollen, 10~200 parts of radix aconiti agrestis powder, 2~50 parts of tuniclike psammosilene root powder, 0.5~15 part of red tuber of pinellia powder, 3~80 parts of yam flour, 2~50 parts of root of kirilow rhodiola powder and 0.05~5 part of borneol.It cooperates between each drug of Chinese medicine composition of the invention, has the function of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal.

Description

A kind of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal Chinese medicine composition
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal Chinese medicine composition.
Background technique
Chinese medicine refers to the drug applied under the guidance of Han Nationality's traditional medical skill.Chinese medicine is divided into Chinese patent drug, Chinese medicine by processing technology Material.Further include other than botanical medicine animal class (such as snake gall, bear gall, long-noded pit viper, pilose antler, deer horn etc.), shell class (such as pearl, Concha meretricis seu cylinae), mineral substance (such as keel, magnetite etc.) etc..
Bruise bruise, wound hemorrhage, hemorrhage of gastrointestinal tract, acute tonsillitis etc. belong to often disease, frequently-occurring disease, therapeutic agent It is more, but also respectively there are advantage and disadvantage.Western medicine curative effect is high, but toxic side effect is big, and Chinese medicine toxic side effect is small, but drug dose is big, makes With inconvenience, and drug effect is low.
Summary of the invention
In view of this, can effectively stop blooding the present invention provides a kind of hemostasis and pain-relieving, the Chinese medicine composition of activating microcirculation and removing stasis medicinal Analgesic, activating microcirculation and removing stasis medicinal.
To solve the above-mentioned problems, the present invention provides following technical schemes:
The present invention provides a kind of hemostasis and pain-relieving, the Chinese medicine composition of activating microcirculation and removing stasis medicinal, the component including following parts by weight: weight 10~400 parts of building powder drapes over one's shoulders 2~50 parts of numb grass meal, 1~20 part of white clouds pollen, 10~200 parts of radix aconiti agrestis powder, tuniclike psammosilene root powder 2~50 Part, 0.5~15 part of red tuber of pinellia powder, 3~80 parts of yam flour, 2~50 parts of root of kirilow rhodiola powder and 0.05~5 part of borneol.
Preferably, the component including following parts by weight: 70~120 parts of Paris polyphylla powder drapes over one's shoulders 10~20 parts of numb grass meal, white clouds pollen 3~7 parts, 20~60 parts of radix aconiti agrestis powder, 5~15 parts of tuniclike psammosilene root powder, 1.5~4 parts of red tuber of pinellia powder, 10~25 parts of yam flour, root of kirilow rhodiola 5~15 parts and 0.1~0.5 part of borneol of powder.
Preferably, the component including following parts by weight: 94.1 parts of Paris polyphylla powder drapes over one's shoulders 14.5 parts of numb grass meal, white clouds pollen 5.0 Part, 44.3 parts of radix aconiti agrestis powder, 11.5 parts of tuniclike psammosilene root powder, 2.7 parts of red tuber of pinellia powder, 16.3 parts of yam flour, 11.3 parts of root of kirilow rhodiola powder and ice 0.3 part of piece.
Preferably, the dosage form of the Chinese medicine composition includes oral agents and external preparation.
Preferably, the oral agents include capsule, tablet, mouth containing agent, pill, sublimed preparation, granule and powder.
Preferably, the external preparation includes aerosol, spray, suppository, ointment, emplastrum, creme and patch.
It preferably, further include pharmaceutically acceptable carrier in the Chinese medicine composition.
Preferably, the pharmaceutically acceptable carrier include: mannitol, sorbierite, sorbic acid, sylvite, sodium pyrosulfite, Sodium hydrogensulfite, sodium thiosulfate, cysteine hydrochloride, thioacetic acid, methionine, vitamin A, vitamin C, vitamin E, dimension Raw element D, azone, EDETATE SODIUM, Ethylenediaminetetraacetic Acid Calcium Salt, the carbonate of monovalence alkali metal, acetate, phosphate, phosphate aqueous solution, salt Acid, acetic acid, sulfuric acid, phosphoric acid, amino acid, sodium chloride, potassium chloride, sodium lactate, xylitol, maltose, glucose, fructose, dextrorotation Glucosides, glycine, starch, sucrose, lactose, mannitol, silicon derivative, cellulose, vitamin derivative, alginates, gelatin, Polyvinylpyrrolidone, glycerol, propylene glycol, ethyl alcohol, polysorbate60-80, Span-80, beeswax, lanolin, atoleine, 16 Alcohol, gallate ester, agar, triethanolamine, basic amino acid, urea, allantoin, calcium carbonate, calcium bicarbonate, surface-active One in agent, polyethylene glycol, cyclodextrin, beta-cyclodextrin, phospholipid material, kaolin, talcum powder, calcium stearate and magnesium stearate Kind is a variety of.
Compared with prior art, technical solution provided by the invention has the advantage that
The present invention provides a kind of hemostasis and pain-relieving, the Chinese medicine composition of activating microcirculation and removing stasis medicinal, the component including following parts by weight: weight 10~400 parts of building powder drapes over one's shoulders 2~50 parts of numb grass meal, 1~20 part of white clouds pollen, 10~200 parts of radix aconiti agrestis powder, tuniclike psammosilene root powder 2~50 Part, 0.5~15 part of red tuber of pinellia powder, 3~80 parts of yam flour, 2~50 parts of root of kirilow rhodiola powder and 0.05~5 part of borneol, the present invention in, weight Building is monarch drug in a prescription, has the effect of swelling and pain relieving, removing blood stasis and hemostasis, radix aconiti agrestis is ministerial drug, it is intended to assist monarch drug in a prescription Paris polyphylla, improve its scattered stasis of blood and stop The effect of pain hemostasis.Above two medicine, a cold heat, is still used in combination like " Xiexin Tang " coptis rhizoma zingiberis of treatise on Febrile Diseases, its department of each row, tool There is swelling and pain relieving, clearing heat and detoxicating, expelling wind and eliminating dampness, broken product dissipating bind, tremble with fear without hot and cold without dry effect.Tuniclike psammosilene root, red scape in side It, yunna cowparsnip, the red tuber of pinellia, drape over one's shoulders numb grass, 6 taste medicinal material of Chinese yam is adjutant altogether.Tuniclike psammosilene root is Caryophyllaceae gold genus plant tuniclike psammosilene root The root of Psammosilene tunicoides W.C.Wu et C.Y.Wu. has hemostasis, dissolving stasis, analgesia, detoxicating functions.It is red Red-spotted stonecrop is the herb of the full valve root of kirilow rhodiola Rhodiola sacra of crassulaceae plants (Prain ex Hamet) Fu, there is promoting blood circulation to stop Blood effect.Yunna cowparsnip, be umbelliferae yunna cowparsnip HeracleumrapulaFranch. dry root, have dispelling wind and eliminating dampness, Active pain relieving effect.The red tuber of pinellia, also known as be aroid packing sow tuber of pinellia Arisaema as headdress flower, the packing sow tuber of pinellia Dry tuber after franchetianum Engl. peeling has the good scattered stasis of blood, removing toxic substances analgesic efficacy.Numb grass is draped over one's shoulders, is lily The dry root of section plant Veratrum Mengtzeanum Loes Veratrum mengtzeanum Loes.f., has effects that eliminating stasis to subdue swelling, pain easing and hemostasis. Chinese yam tonifying spleen nourishing the stomach, engender liquid and benefic lung can mitigate injury of all medicines to spleen and stomach function to consolidate, and reach eliminating evil and do not hurt just.Borneol tool Have inducing resuscitation of having one's ideas straightened out, the function of clearing away heat to and alleviating pain, and gas faint scent, be added in side this product a little also can flavoring, to make medicine in side.
Embodiment the result shows that: Chinese medicine composition provided by the invention being capable of effectively hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal.
Specific embodiment
The present invention provides a kind of hemostasis and pain-relieving, the Chinese medicine composition of activating microcirculation and removing stasis medicinal, the component including following parts by weight: weight 10~400 parts of building powder drapes over one's shoulders 2~50 parts of numb grass meal, 1~20 part of white clouds pollen, 10~200 parts of radix aconiti agrestis powder, tuniclike psammosilene root powder 2~50 Part, 0.5~15 part of red tuber of pinellia powder, 3~80 parts of yam flour, 2~50 parts of root of kirilow rhodiola powder and 0.05~5 part of borneol.
Hemostasis and pain-relieving provided by the invention, activating microcirculation and removing stasis medicinal Chinese medicine composition in, preferably include Paris polyphylla Paris polyphylla powder 70~120 Part drapes over one's shoulders 10~20 parts of numb grass meal, 3~7 parts of white clouds pollen, 20~60 parts of radix aconiti agrestis powder, 5~15 parts of tuniclike psammosilene root powder, red tuber of pinellia powder 1.5 ~4 parts, 10~25 parts of yam flour, 5~15 parts of root of kirilow rhodiola powder and 0.1~0.5 part of borneol, more preferably 94.1 parts of Paris polyphylla powder drape over one's shoulders 14.5 parts of numb grass meal, 5.0 parts of white clouds pollen, 44.3 parts of radix aconiti agrestis powder, 11.5 parts of tuniclike psammosilene root powder, 2.7 parts of red tuber of pinellia powder, yam flour 16.3 parts, 11.3 parts of root of kirilow rhodiola powder and 0.3 part of borneol.
In the present invention, the Paris polyphylla is monarch drug in a prescription.Paris polyphylla also known as paris polyphylla.Bitter, cold nature enter Liver Channel blood system, have and disappear The effect of swollen analgesic, removing blood stasis and hemostasis, the wild aconite root, it is intended to assist monarch drug in a prescription Paris polyphylla, improve the effect of its removing blood stasis and acesodyne hemostasis, together When have good analgesic effect.Wild aconite root is pungent, big heat, with Paris polyphylla compatibility, above two medicine, a cold heat, still like " typhoid fever By " " Xiexin Tang " coptis rhizoma zingiberis be used in combination, its department of each row has swelling and pain relieving, clearing heat and detoxicating, expelling wind and eliminating dampness, broken product dissipating bind, cold Without hot and cold without dry effect.Meanwhile assistant is with tuniclike psammosilene root hemostasis, dissolving stasis, analgesia, removing toxic substances, root of kirilow rhodiola hemostasis promoting blood circulation, white clouds Flower dispelling wind and eliminating dampness, active pain relieving, the red tuber of pinellia dissipates the stasis of blood, removing toxic substances relieves pain, effect more writes, and drapes over one's shoulders numb careless eliminating stasis to subdue swelling, pain easing and hemostasis, Chinese yam Tonifying spleen nourishing the stomach, engender liquid and benefic lung reach eliminating evil and do not hurt just to consolidate, and a little flavoring of borneol is to make.
In the present invention, it is also preferable to include pharmaceutically acceptable carriers in the Chinese medicine composition.
In the present invention, the pharmaceutically acceptable carrier preferably includes: mannitol, sorbierite, sorbic acid, sylvite, coke Sodium sulfite, sodium hydrogensulfite, sodium thiosulfate, cysteine hydrochloride, thioacetic acid, methionine, vitamin A, vitamin C, Vitamin E, vitamin D, azone, EDETATE SODIUM, Ethylenediaminetetraacetic Acid Calcium Salt, the carbonate of monovalence alkali metal, acetate, phosphate, phosphoric acid Saline solution, hydrochloric acid, acetic acid, sulfuric acid, phosphoric acid, amino acid, sodium chloride, potassium chloride, sodium lactate, xylitol, maltose, grape Sugar, fructose, dextran, glycine, starch, sucrose, lactose, mannitol, silicon derivative, cellulose, vitamin derivative, Alginates, gelatin, polyvinylpyrrolidone, glycerol, propylene glycol, ethyl alcohol, polysorbate60-80, Span-80, beeswax, lanolin, liquid Body paraffin, hexadecanol, gallate ester, agar, triethanolamine, basic amino acid, urea, allantoin, calcium carbonate, bicarbonate Calcium, surfactant, polyethylene glycol, cyclodextrin, beta-cyclodextrin, phospholipid material, kaolin, talcum powder, calcium stearate and hard One of fatty acid magnesium is a variety of.
In the present invention, the hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal the preparation method of Chinese medicine composition preferably include to walk as follows It is rapid:
1) Paris polyphylla is infiltrated, slice, then infiltrated through saturated limewater through saturated limewater, is dried after being floated with water to neutrality, It obtains processing Paris polyphylla, the processing Paris polyphylla is crushed, cross 90~110 meshes, obtain Paris polyphylla powder;
2) radix aconiti agrestis is handled to 5~15min at 95~100 DEG C, obtains processing radix aconiti agrestis, by the processing radix aconiti agrestis 95~ It is dried again after steaming 2~3h at 105 DEG C, obtains processing radix aconiti agrestis (i.e. wild aconite root), the processing radix aconiti agrestis is crushed, cross 90~110 mesh Sieve, obtains radix aconiti agrestis powder;
3) red tuber of pinellia slice will be removed the peel, then with drying, crushing after 2~4d of water infiltration, crosses 90~110 meshes, obtains red half Xia Fen;
4) by Chinese yam, drape over one's shoulders numb grass, tuniclike psammosilene root, root of kirilow rhodiola and yunna cowparsnip and be respectively dried, crush, cross 90~110 meshes, incite somebody to action To yam flour, drape over one's shoulders numb grass meal, tuniclike psammosilene root powder, root of kirilow rhodiola powder and white clouds pollen mixing after obtain mixed powder;
5) borneol is crushed, crosses 90~110 meshes, obtains borneol powder;
6) by step 1) the Paris polyphylla powder, step 2) radix aconiti agrestis powder, the red tuber of pinellia powder of step 3), step 4) mixed powder and step 5) The mixing of borneol powder, obtains Chinese medicine composition.
Step 1)~5) it is limited without time sequencing.
The present invention preferably infiltrates Paris polyphylla through saturated limewater infiltration, slice, then through saturated limewater, is floated with water to neutrality After dry, obtain process Paris polyphylla, by the processings Paris polyphylla crush, mistake 90~110 meshes, obtain Paris polyphylla powder.
The specification that the present invention is sliced the Paris polyphylla is not particularly limited, using the specification of conventional cutting Paris polyphylla.
In the present invention, the time that the Paris polyphylla is infiltrated through saturated limewater every time is preferably 24~36h, and more preferably 28 ~32h, most preferably 30h.
It is in the present invention, described that float the drying time to neutral Paris polyphylla with water be preferably 5~10h, more preferably 6~ 9h, most preferably 7~8h;The temperature of the drying is preferably 55~65 DEG C, more preferably 58~62 DEG C, most preferably 60 DEG C.
The condition that the present invention crushes the processing Paris polyphylla is not particularly limited, and is using the conventional condition for crushing drug It can.
In the present invention, preferred 90~110 mesh of mistake after the processing Paris polyphylla crushes, more preferably sieves with 100 mesh sieve.
Radix aconiti agrestis is preferably handled 5~15min by the present invention at 95~100 DEG C, processing radix aconiti agrestis is obtained, by the processing radix aconiti agrestis It is dried again after steaming 2~3h at 95~105 DEG C, obtains processing radix aconiti agrestis, the processing radix aconiti agrestis is crushed, cross 90~110 meshes, obtain To radix aconiti agrestis powder.
In the present invention, the radix aconiti agrestis is reprocessed after being preferably sliced, and the specification after the present invention is sliced the radix aconiti agrestis does not have Particular determination, using the specification of conventional cutting radix aconiti agrestis.
In the present invention, the radix aconiti agrestis handles 8~12min preferably at 100 DEG C, and the processing is particularly preferred as: by institute It states radix aconiti agrestis and is placed in water and handled.
In the present invention, dry blowing again after the processing radix aconiti agrestis preferably drains away the water, the processing radix aconiti agrestis is preferably at 100 DEG C Dry blowing 2.5h.
In the present invention, the time that the processing radix aconiti agrestis is dried again after steaming is preferably 6~10h, more preferably 7~9h, most Preferably 8h;The temperature of the drying is preferably 80~90 DEG C, and more preferably 85 DEG C.
In the present invention, preferred 90~110 mesh of mistake after the processing radix aconiti agrestis crushes, more preferably sieves with 100 mesh sieve.
The present invention will preferably remove the peel red tuber of pinellia slice, then with drying, crushing after 2~4d of water infiltration, cross 90~110 meshes, Obtain red tuber of pinellia powder.
The present invention is not particularly limited the condition of the red tuber of pinellia slice of the peeling, using the condition of the red tuber of pinellia of conventional cutting ?.
The present invention will preferably remove the peel red tuber of pinellia slice again with drying after 2~4d of water infiltration, dry after preferably infiltration 3d, described Water is preferably replaced 2 times daily.
The present invention is dried again after preferably the red tuber of pinellia after water infiltration drains away the water, and the time of the drying is preferably 6 ~10h, more preferably 7~9h, most preferably 8h;The temperature of the drying is preferably 80~90 DEG C, and more preferably 85 DEG C.
The present invention preferably by Chinese yam, drape over one's shoulders numb grass, tuniclike psammosilene root, root of kirilow rhodiola and yunna cowparsnip and be respectively dried, crush, mistake 90~110 Mesh by obtained yam flour, drapes over one's shoulders numb grass meal, obtains mixed powder after tuniclike psammosilene root powder, root of kirilow rhodiola powder and white clouds pollen mix.
The present invention is not special to the Chinese yam, the condition draping over one's shoulders numb grass, tuniclike psammosilene root, root of kirilow rhodiola and yunna cowparsnip drying, crushing It limits, using the conventional condition dried and crush drug.
In the present invention, by the Chinese yam, drape over one's shoulders preferred mistake 90 after numb grass, tuniclike psammosilene root, root of kirilow rhodiola and yunna cowparsnip crush respectively ~110 meshes, more preferably sieve with 100 mesh sieve.
The present invention preferably crushes borneol, preferably sieves with 100 mesh sieve, and obtains borneol powder.
Paris polyphylla powder, radix aconiti agrestis powder, red tuber of pinellia powder, mixed powder and the mixing of borneol powder that the present invention obtains above-mentioned technical proposal, Obtain the Chinese medicine composition of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal.
In the present invention, the hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal the dosage form of Chinese medicine composition preferably include oral agents and outer Use preparation.The dosage form of the oral agents preferably includes capsule, tablet, mouth containing agent, pill, sublimed preparation, granule and powder, more excellent It is selected as capsule and powder.In the present invention, the tablet preferably includes sugar coated tablet, film coated tablet and enteric coated tablet. In the present invention, the external preparation preferably includes aerosol, spray, suppository, ointment, emplastrum, creme and patch.
In the present invention, the application method of the capsule (specification: 0.2g) preferably includes: 1. take orally: once a grain, one It is 3 times;2. external application: taking capsule 's content appropriate, directly spread affected part or dress affected part with 70%~75% ethyl alcohol.In the present invention In, the application method of the powder are as follows: 1. take orally: three times a day, a 0.2g;2. external application: taking medicinal powder appropriate, directly spread affected part Or affected part is dressed with 70%~75% ethyl alcohol.In the present invention, (often pressing average the amount of injection for every bottle must not be less than the spray Application method 50mg) are as follows: the agent is sprayed against wound, under once spraying 1~2,3~5 times on the one.
In order to further illustrate the present invention, technical solution provided by the invention is retouched in detail below with reference to embodiment It states, but they cannot be interpreted as limiting the scope of the present invention.
Embodiment 1 (capsule)
1) Paris polyphylla saturated limewater is infiltrated for 24 hours, is drained, is sliced, then infiltrated 24 hours with saturated limewater, then used Water is floated to neutrality, is drained, and is put into drying box at 55 DEG C and is dried 5 hours, obtains Paris polyphylla medicinal material processing product.By the Paris polyphylla after processing Medicinal material smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder I), spare.
2) Radix Aconiti Kusnezoffii is sliced, puts into boiling water and rob water 5 minutes, pulls out, drain.It is put into cooker again at 100 DEG C Dry blowing 2 hours.Medicinal material is released, is dried, is put into drying box and is dried 6 hours at 85 DEG C, obtain Radix Aconiti Kusnezoffii processed product.It will process Radix Aconiti Kusnezoffii afterwards smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder II), spare.
3) the red tuber of pinellia, slice will be removed the peel, with water infiltration 3 days (changing water daily 2 times), drains, is put into drying box at 80 DEG C Drying smashes after 6-10 hours, sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder III), spare.
4) by Chinese yam, draping over one's shoulders numb grass, turniplike cowparsnip root, tuniclike psammosilene root and root of kirilow rhodiola, to dry 6 at 80-90 DEG C in drying box respectively small When after smash, sieve with 100 mesh sieve, by obtained yam flour, drape over one's shoulders numb grass meal, turniplike cowparsnip root powder, tuniclike psammosilene root powder and root of kirilow rhodiola powder with matter For amount than being after 16.3:14.5:5:11.5:11.3 is mixed, to be placed in the container of clean dried, labelling (medicinal material dry powder IV) is standby With.
5) borneol is smashed, is sieved with 100 mesh sieve, is placed in the container of clean dried, labelled (medicinal powder V).
6) successively 94.1g, 44.3g, 2.7g and 58.6g and V 0.3g of medicinal powder are sufficiently mixed weighing medicinal material dry powder I-IV It is even, obtain Chinese medicine composition.
7) the Chinese medicine composition powder is distributed into 1000 No. 1 capsules.
Usage: it 1. takes orally: once a grain, three times a day;2. external application: taking capsule 's content appropriate, directly spread affected part or use 70%~75% ethyl alcohol dresses affected part.
Embodiment 2 (capsule)
1) Paris polyphylla saturated limewater is infiltrated into 36h, drained, is sliced, then infiltrated 24 hours with saturated limewater, then used Water is floated to neutrality, is drained, and is put into drying box at 55 DEG C and is dried 5 hours, obtains Paris polyphylla medicinal material processing product.By the Paris polyphylla after processing Medicinal material smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder I), spare.
2) Radix Aconiti Kusnezoffii is sliced, puts into boiling water and rob water 10 minutes, pulls out, drain.It is put into cooker again at 100 DEG C Dry blowing 2 hours.Medicinal material is released, is dried, is put into drying box and is dried 6 hours at 90 DEG C, obtain Radix Aconiti Kusnezoffii processed product.It will process Radix Aconiti Kusnezoffii afterwards smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder II), spare.
3) the red tuber of pinellia, slice will be removed the peel, with water infiltration 2 days (changing water daily 2 times), drains, is put into drying box at 80 DEG C Drying smashes after 6-10 hours, sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder III), spare.
4) by Chinese yam, drape over one's shoulders numb grass, turniplike cowparsnip root, tuniclike psammosilene root and root of kirilow rhodiola and dried 6 hours at 90 DEG C in drying box respectively After smash, sieve with 100 mesh sieve, by obtained yam flour, drape over one's shoulders numb grass meal, turniplike cowparsnip root powder, tuniclike psammosilene root powder and root of kirilow rhodiola powder with quality It after for 20:10:3.8:15:9 mixing, is placed in the container of clean dried, labels (medicinal material dry powder IV), it is spare.
5) borneol is smashed, is sieved with 100 mesh sieve, is placed in the container of clean dried, labelled (medicinal powder V).
6) successively 110g, 30g, 2g and 57.8g and V 0.2g of medicinal powder are sufficiently mixed uniformly weighing medicinal material dry powder I-IV, are obtained Chinese medicine composition.
7) the Chinese medicine composition powder is distributed into 1000 No. 1 capsules.
Usage: it 1. takes orally: once a grain, three times a day;2. external application: taking capsule 's content appropriate, directly spread affected part or use 70%~75% ethyl alcohol dresses affected part.
Embodiment 3 (capsule)
1) Paris polyphylla saturated limewater is infiltrated for 24 hours, is drained, is sliced, then infiltrated 30 hours with saturated limewater, then used Water is floated to neutrality, is drained, and is put into drying box at 65 DEG C and is dried 8 hours, obtains Paris polyphylla medicinal material processing product.By the Paris polyphylla after processing Medicinal material smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder I), spare.
2) Radix Aconiti Kusnezoffii is sliced, puts into boiling water and rob water 12 minutes, pulls out, drain.It is put into cooker again at 100 DEG C Dry blowing 3 hours.Medicinal material is released, is dried, is put into drying box and is dried 6 hours at 85 DEG C, obtain Radix Aconiti Kusnezoffii processed product.It will process Radix Aconiti Kusnezoffii afterwards smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder II), spare.
3) the red tuber of pinellia, slice will be removed the peel, with water infiltration 4 days (changing water daily 2 times), drains, is put into drying box at 90 DEG C Drying smashes after 6-10 hours, sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material dry powder III), spare.
4) by Chinese yam, drape over one's shoulders numb grass, turniplike cowparsnip root, tuniclike psammosilene root and root of kirilow rhodiola and dried 6 hours at 80 DEG C in drying box respectively After smash, sieve with 100 mesh sieve, by obtained yam flour, drape over one's shoulders numb grass meal, turniplike cowparsnip root powder, tuniclike psammosilene root powder and root of kirilow rhodiola powder with quality It after for 23:18:7:8:5 mixing, is placed in the container of clean dried, labels (medicinal material dry powder IV), it is spare.
5) borneol is smashed, is sieved with 100 mesh sieve, is placed in the container of clean dried, labelled (medicinal powder V).
6) successively 85g, 50g, 3.6g and 61g and V 0.4g of medicinal powder are sufficiently mixed uniformly weighing medicinal material dry powder I-IV, are obtained Chinese medicine composition.
7) the Chinese medicine composition powder is distributed into 1000 No. 1 capsules.
Usage: it 1. takes orally: once a grain, three times a day;2. external application: taking capsule 's content appropriate, directly spread affected part or use 70%~75% ethyl alcohol dresses affected part.
Embodiment 4 (powder)
1) Paris polyphylla saturated limewater is infiltrated into 36h, drained, is sliced, then infiltrate 36h with saturated limewater, then use water Drift drains to neutrality, is put into drying box and dries 10h at 65 DEG C, obtain Paris polyphylla medicinal material processing product.By the Paris polyphylla medicinal material after processing It smashes, sieves with 100 mesh sieve, be placed in the container of clean dried, label (medicinal material dry powder I), it is spare.
2) Radix Aconiti Kusnezoffii is sliced, puts into boiling water and rob water 5min, pulls out, drain.It puts into cooker and is done at 100 DEG C again Steam 3h.Medicinal material is released, is dried, is put into drying box in 85 DEG C of drying 10h, obtains Radix Aconiti Kusnezoffii processed product.By the grass after processing Root of three-nerved spicebush material smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material does II), spare.
3) the red tuber of pinellia, slice will be removed the peel, with water infiltration 3 days (changing water daily 2 times), drains, is put into drying box at 90 DEG C It is smashed after drying 10h, sieves with 100 mesh sieve, be placed in the container of clean dried, labelled (medicinal material dry powder III), it is spare.
4) by Chinese yam, drape over one's shoulders numb grass, turniplike cowparsnip root, tuniclike psammosilene root and the root of kirilow rhodiola powder after drying 6h at 90 DEG C in drying box respectively Essence sieves with 100 mesh sieve, and by obtained yam flour, drapes over one's shoulders numb grass meal, turniplike cowparsnip root powder, tuniclike psammosilene root powder and root of kirilow rhodiola powder with mass ratio and is 16.3:14.5:5:11.5:11.3 being placed in the container of clean dried after mixing, label (medicinal material dry powder IV), it is spare.
5) borneol is smashed, is sieved with 100 mesh sieve, is placed in the container of clean dried, labelled (medicinal powder V).
6) by above-mentioned medicinal material dry powder I-IV, successively 94.1g, 44.3g, 2.7g and 58.6g and medicinal powder V 0.3g are sufficiently mixed It is even, obtain Chinese medicine composition.
7) the Chinese medicine composition powder is distributed into porcelain vase, per bottled 3g.
Usage: it 1. takes orally: three times a day, a 0.2g;2. external application: take medicinal powder appropriate, directly spread affected part or with 70%~ 75% ethyl alcohol dresses affected part.
Embodiment 5 (powder)
1) Paris polyphylla saturated limewater is infiltrated into 36h, drained, is sliced, then for 24 hours with saturated limewater infiltration, then use water Drift drains to neutrality, is put into drying box and dries 5h at 65 DEG C, obtain Paris polyphylla medicinal material processing product.By the Paris polyphylla medicinal material after processing It smashes, sieves with 100 mesh sieve, be placed in the container of clean dried, label (medicinal material dry powder I), it is spare.
2) Radix Aconiti Kusnezoffii is sliced, puts into boiling water and rob water 15min, pulls out, drain.It is put into cooker again at 100 DEG C Dry blowing 3h.Medicinal material is released, is dried, is put into drying box in 85 DEG C of drying 6h, obtains Radix Aconiti Kusnezoffii processed product.By the grass after processing Root of three-nerved spicebush material smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material does II), spare.
3) the red tuber of pinellia, slice will be removed the peel, with water infiltration 3 days (changing water daily 2 times), drains, is put into drying box at 80 DEG C It is smashed after drying 10h, sieves with 100 mesh sieve, be placed in the container of clean dried, labelled (medicinal material dry powder III), it is spare.
4) by Chinese yam, drape over one's shoulders numb grass, turniplike cowparsnip root, tuniclike psammosilene root and the root of kirilow rhodiola powder after drying 6h at 90 DEG C in drying box respectively Essence sieves with 100 mesh sieve, and by obtained yam flour, drapes over one's shoulders numb grass meal, turniplike cowparsnip root powder, tuniclike psammosilene root powder and root of kirilow rhodiola powder with mass ratio and is It after 20:10:3.8:15:9 mixing, is placed in the container of clean dried, labels (medicinal material dry powder IV), it is spare.
5) borneol is smashed, is sieved with 100 mesh sieve, is placed in the container of clean dried, labelled (medicinal powder V).
6) by above-mentioned medicinal material dry powder I-IV, successively 110g, 30g, 2g and 57.8g and V 0.2g of medicinal powder are sufficiently mixed uniformly, are obtained To Chinese medicine composition.
7) the Chinese medicine composition powder is distributed into porcelain vase, per bottled 3g.
Usage: it 1. takes orally: three times a day, a 0.2g;2. external application: take medicinal powder appropriate, directly spread affected part or with 70%~ 75% ethyl alcohol dresses affected part.
Embodiment 6 (powder)
1) Paris polyphylla saturated limewater is infiltrated into 36h, drained, is sliced, then for 24 hours with saturated limewater infiltration, then use water Drift drains to neutrality, is put into drying box and dries 5h at 60 DEG C, obtain Paris polyphylla medicinal material processing product.By the Paris polyphylla medicinal material after processing It smashes, sieves with 100 mesh sieve, be placed in the container of clean dried, label (medicinal material dry powder I), it is spare.
2) Radix Aconiti Kusnezoffii is sliced, puts into boiling water and rob water 10min, pulls out, drain.It is put into cooker again at 100 DEG C Dry blowing 3h.Medicinal material is released, is dried, is put into drying box in 85 DEG C of drying 6h, obtains Radix Aconiti Kusnezoffii processed product.By the grass after processing Root of three-nerved spicebush material smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material does II), spare.
3) the red tuber of pinellia, slice will be removed the peel, with water infiltration 3 days (changing water daily 2 times), drains, is put into drying box at 80 DEG C It is smashed after drying 10h, sieves with 100 mesh sieve, be placed in the container of clean dried, labelled (medicinal material dry powder III), it is spare.
4) by Chinese yam, drape over one's shoulders numb grass, turniplike cowparsnip root, tuniclike psammosilene root and the root of kirilow rhodiola powder after drying 6h at 90 DEG C in drying box respectively Essence sieves with 100 mesh sieve, and by obtained yam flour, drapes over one's shoulders numb grass meal, turniplike cowparsnip root powder, tuniclike psammosilene root powder and root of kirilow rhodiola powder with mass ratio and is It after 23:18:7:8:5 mixing, is placed in the container of clean dried, labels (medicinal material dry powder IV), it is spare.
5) borneol is smashed, is sieved with 100 mesh sieve, is placed in the container of clean dried, labelled (medicinal powder V).
6) by above-mentioned medicinal material dry powder I-IV, successively 85g, 50g, 3.6g and 61g and V 0.4g of medicinal powder are sufficiently mixed uniformly, are obtained To Chinese medicine composition.
7) the Chinese medicine composition powder is distributed into porcelain vase, per bottled 3g.
Usage: it 1. takes orally: three times a day, a 0.2g;2. external application: take medicinal powder appropriate, directly spread affected part or with 70%~ 75% ethyl alcohol dresses affected part.
Embodiment 7 (spray)
1) Paris polyphylla saturated limewater is infiltrated into 30h, drained, is sliced, then infiltrate 28h with saturated limewater, then use water Drift drains to neutrality, is put into drying box and dries 8h at 60 DEG C, obtain Paris polyphylla medicinal material processing product.By the Paris polyphylla medicinal material after processing It smashes, sieves with 100 mesh sieve, be placed in the container of clean dried, label (medicinal material dry powder I), it is spare.
2) Radix Aconiti Kusnezoffii is sliced, puts into boiling water and rob water 10min, pulls out, drain.It is put into cooker again at 100 DEG C Dry blowing 2.5h.Medicinal material is released, is dried, is put into drying box in 85 DEG C of drying 8h, obtains Radix Aconiti Kusnezoffii processed product.After processing Radix Aconiti Kusnezoffii smashes, and sieves with 100 mesh sieve, is placed in the container of clean dried, labels (medicinal material does II), spare.
3) the red tuber of pinellia, slice will be removed the peel, with water infiltration 3 days (changing water daily 2 times), drains, is put into drying box at 85 DEG C It is smashed after drying 8h, sieves with 100 mesh sieve, be placed in the container of clean dried, labelled (medicinal material dry powder III), it is spare.
4) by Chinese yam, drape over one's shoulders numb grass, turniplike cowparsnip root, tuniclike psammosilene root and the root of kirilow rhodiola powder after drying 6h at 85 DEG C in drying box respectively Essence sieves with 100 mesh sieve, and by obtained yam flour, drapes over one's shoulders numb grass meal, turniplike cowparsnip root powder, tuniclike psammosilene root powder and root of kirilow rhodiola powder with mass ratio and is 16.3:14.5:5:11.5:11.3 being placed in the container of clean dried after mixing, label (medicinal material dry powder IV), it is spare.
5) borneol is smashed, is sieved with 100 mesh sieve, is placed in the container of clean dried, labelled (medicinal powder V).
6) by above-mentioned medicinal material dry powder I-IV, successively 94.1g, 44.3g, 2.7g and 58.6g and medicinal powder V 0.3g are sufficiently mixed It is even, obtain Chinese medicine composition.
7) 50% alcohol reflux of Chinese medicine composition medicinal powder is extracted.Extracting solution adds 50% ethyl alcohol adjustment total amount extremely 1000ml is mixed, filtration, spray of bottling to obtain.
Usage: alignment wound sprays the agent.
Embodiment 8
The Chinese traditional medicine composition composition powders that embodiment 4 is prepared carry out animal experiment study, the results are shown in Table 1.
1 Results of Animal of table
By table 1, it can be concluded that, Chinese medicine composition provided by the invention has the function of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (8)

1. the Chinese medicine composition of a kind of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal, which is characterized in that the component including following parts by weight: Paris polyphylla 10~400 parts of powder, drape over one's shoulders 2~50 parts of numb grass meal, 1~20 part of white clouds pollen, 10~200 parts of radix aconiti agrestis powder, 2~50 parts of tuniclike psammosilene root powder, 0.5~15 part of red tuber of pinellia powder, 3~80 parts of yam flour, 2~50 parts of root of kirilow rhodiola powder and 0.05~5 part of borneol.
2. Chinese medicine composition according to claim 1, which is characterized in that the component including following parts by weight: Paris polyphylla powder 70 ~120 parts, drape over one's shoulders 10~20 parts of numb grass meal, 3~7 parts of white clouds pollen, 20~60 parts of radix aconiti agrestis powder, 5~15 parts of tuniclike psammosilene root powder, the red tuber of pinellia 1.5~4 parts of powder, 10~25 parts of yam flour, 5~15 parts of root of kirilow rhodiola powder and 0.1~0.5 part of borneol.
3. Chinese medicine composition according to claim 2, which is characterized in that the component including following parts by weight: Paris polyphylla powder 94.1 parts, drape over one's shoulders 14.5 parts of numb grass meal, 5.0 parts of white clouds pollen, 44.3 parts of radix aconiti agrestis powder, 11.5 parts of tuniclike psammosilene root powder, red tuber of pinellia powder 2.7 Part, 16.3 parts of yam flour, 11.3 parts of root of kirilow rhodiola powder and 0.3 part of borneol.
4. Chinese medicine composition according to any one of claims 1 to 3, which is characterized in that the agent of the Chinese medicine composition Type includes oral agents and external preparation.
5. Chinese medicine composition according to claim 4, which is characterized in that the oral agents include capsule, tablet, mouth containing Agent, pill, sublimed preparation and powder.
6. Chinese medicine composition according to claim 4, which is characterized in that the external preparation include aerosol, spray, Suppository, ointment, emplastrum, creme and patch.
7. Chinese medicine composition according to any one of claims 1 to 3, which is characterized in that in the Chinese medicine composition also Including pharmaceutically acceptable carrier.
8. Chinese medicine composition according to claim 7, which is characterized in that the pharmaceutically acceptable carrier includes: sweet dew Alcohol, sorbierite, sorbic acid, sylvite, sodium pyrosulfite, sodium hydrogensulfite, sodium thiosulfate, cysteine hydrochloride, thioacetic acid, Methionine, vitamin A, vitamin C, vitamin E, vitamin D, azone, EDETATE SODIUM, Ethylenediaminetetraacetic Acid Calcium Salt, monovalence alkali metal carbon Hydrochlorate, acetate, phosphate, phosphate aqueous solution, hydrochloric acid, acetic acid, sulfuric acid, phosphoric acid, amino acid, sodium chloride, potassium chloride, lactic acid Sodium, xylitol, maltose, glucose, fructose, dextran, glycine, starch, sucrose, lactose, mannitol, silicon are derivative Object, cellulose, vitamin derivative, alginates, gelatin, polyvinylpyrrolidone, glycerol, propylene glycol, ethyl alcohol, polysorbate60-80, Span-80, beeswax, lanolin, atoleine, hexadecanol, gallate ester, agar, triethanolamine, basic amino acid, urine Element, allantoin, calcium carbonate, calcium bicarbonate, surfactant, polyethylene glycol, cyclodextrin, beta-cyclodextrin, phospholipid material, kaolinite One of soil, talcum powder, calcium stearate and magnesium stearate are a variety of.
CN201910084508.7A 2019-01-29 2019-01-29 A kind of hemostasis and pain-relieving, activating microcirculation and removing stasis medicinal Chinese medicine composition Withdrawn CN109692262A (en)

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Application publication date: 20190430